phenytoin and phencyclidine

phenytoin has been researched along with phencyclidine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's5 (31.25)18.2507
2000's5 (31.25)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Jolivette, LJ; Ward, KW1
Abraham, MH; Acree, WE; Ibrahim, A1
Andricopulo, AD; Moda, TL; Montanari, CA1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Sage, GP; Sethy, VH1
Davis, WM; Hackett, RB; Obrosky, KW; Waters, IW1
Boxer, PA; Cordon, JJ; Mann, ME; Marcoux, FW; Rock, DM; Rodolosi, LC; Taylor, CP; Vartanian, MG1
De Prins, E; Marrannes, R; Wauquier, A; Willems, R1
Goode, DJ; Meltzer, HY1
duSouich, P; Lalka, D; Ludden, TM; McLean, AJ; Vicuna, A; Vicuna, N1
Pèzzola, A; Popoli, P; Sagratella, S1
Kamei, H; Kameyama, T; Nabeshima, T1

Other Studies

16 other study(ies) available for phenytoin and phencyclidine

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Phencyclidine-a different hallucinogen.
    The Medical letter on drugs and therapeutics, 1977, Aug-26, Volume: 19, Issue:17

    Topics: Diazepam; Hallucinations; Humans; Phencyclidine; Phenytoin; Substance-Related Disorders

1977
Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, diazepam and phenytoin.
    Neuropharmacology, 1992, Volume: 31, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Anticonvulsants; Corpus Striatum; Diazepam; Dizocilpine Maleate; In Vitro Techniques; N-Methylaspartate; Phencyclidine; Phenytoin; Potassium; Pyrrolidines; Rats

1992
Factors in the lethality of i.v. phencyclidine in conscious dogs.
    General pharmacology, 1991, Volume: 22, Issue:4

    Topics: Animals; Dogs; Female; Heart; Infusions, Intravenous; Male; Pancuronium; Phencyclidine; Phenytoin; Respiration, Artificial; Seizures; Time Factors

1991
Comparison of phenytoin with noncompetitive N-methyl-D-aspartate antagonists in a model of focal brain ischemia in rat.
    Stroke, 1990, Volume: 21, Issue:11 Suppl

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred F344

1990
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
    Brain research, 1988, Aug-09, Volume: 457, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1988
Cytotoxic effects of imipramine on platelets.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Animals; Blood Cell Count; Blood Platelets; Calcium Chloride; Chlorpromazine; Creatine Kinase; Edetic Acid; Humans; Imipramine; L-Lactate Dehydrogenase; Magnesium; Male; Ouabain; Phencyclidine; Phenytoin; Rats; Temperature; Thrombin

1974
Dose-dependence of the apparent half-life of phenytoin in the rat.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:1

    Topics: Anesthesia; Animals; Biotransformation; Dose-Response Relationship, Drug; Half-Life; Kinetics; Pentobarbital; Phencyclidine; Phenytoin; Rats

1980
Diphenylhydantoin potentiates the EEG and behavioural effects induced by N-methyl-D-aspartate antagonists in rats.
    Psychopharmacology, 1994, Volume: 113, Issue:3-4

    Topics: Animals; Behavior, Animal; Cortical Synchronization; Dizocilpine Maleate; Drug Synergism; Electroencephalography; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Pipecolic Acids; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stereotyped Behavior

1994
(+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites.
    European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Phenazocine; Phencyclidine; Phenytoin; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stress, Physiological

1996