phenytoin and perphenazine

phenytoin has been researched along with perphenazine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Gralla, EJ; Hayden, DW; Mattsson, JL; Sabo, JP; Yochmowitz, MG1
Bahler, A; Pincus, J; Schneider, RR; Stimmel, B1
Kamei, C; Shimomura, K; Ueki, S1
Grinberg, KN; Shapiro, IuL; Vaĭntrub, MIa; Zhurkov, VS1
Kanzler, M; Malitz, S1

Reviews

2 review(s) available for phenytoin and perphenazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agents; Arm; Barbiturates; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Cricetinae; Drosophila; Female; Heart Defects, Congenital; Humans; Imipramine; Infant, Newborn; Jaundice, Neonatal; Mutagens; Perphenazine; Phenothiazines; Phenytoin; Pregnancy; Primidone; Rabbits; Thalidomide; Tranquilizing Agents; Trifluoperazine

1972

Trials

1 trial(s) available for phenytoin and perphenazine

ArticleYear
Are antidepressants better than placebo?
    The American journal of psychiatry, 1971, Volume: 127, Issue:12

    Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Dextroamphetamine; Diazepam; Dibenzocycloheptenes; Fatigue; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Phenytoin; Placebos; Propylamines; Sleep; Xerostomia

1971

Other Studies

11 other study(ies) available for phenytoin and perphenazine

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
The effect of selected drugs on first-stage radioemesis in beagle dogs.
    Radiation research, 1979, Volume: 78, Issue:2

    Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhydramine; Dogs; Drug Combinations; Perphenazine; Phenytoin; Radiation Injuries, Experimental; Scopolamine; Vomiting; X-Rays

1979
Asymptomatic idiopathic syndrome of prolonged Q-T interval in a 45-year-old woman. Ventricular tachyarrhythmias precipitated by hypokalemia and therapy with amitriptyline and prephenazine.
    Chest, 1977, Volume: 71, Issue:2

    Topics: Amitriptyline; Bretylium Tosylate; Electrocardiography; Female; Heart Ventricles; Humans; Hypokalemia; Middle Aged; Perphenazine; Phenytoin; Propranolol; Syncope; Syndrome; Tachycardia

1977
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome

1973