phenytoin and pentobarbital

phenytoin has been researched along with pentobarbital in 129 studies

Research

Studies (129)

TimeframeStudies, this research(%)All Research%
pre-199098 (75.97)18.7374
1990's9 (6.98)18.2507
2000's6 (4.65)29.6817
2010's15 (11.63)24.3611
2020's1 (0.78)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Caron, G; Ermondi, G1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Berl, S; Nicklas, WJ; Weinberger, J1
Cooper, BS; Hawk, HW1
Grille, W; Johnsen, K; Kolenda, KD1
Leung, I; Miller, JC1
Fenner, WR; Powers, JD; Sanders, JE; Yeary, RA1
Boisse, NR; Okamoto, M; Rosenberg, HC1
Hoffer, BJ; Oliver, AP; Wyatt, RJ1
Lomas, TE; Smith, RD1
Afshar, F; Koeze, TH; Wylie, IG1
Ehrnebo, M; Odar-Cederlöf, I2
Haacke, H; Johnsen, K; Kolenda, KD2
Butler, CM; Hill, RM; Horning, MG; Lertratanangkoon, K; Nowlin, J; Sommer, K1
Barker, JL2
Gigon, PL1
Corcia, RM; Gay, PE; Lamon, S; Leaf, RC; Wnek, DJ1
Grossman, Y; Schleifstein-Attias, D; Silberstein, E1
Dupuis, RE; Miranda-Massari, J1
Kulkarni, SK; Ticku, MK1
Bock, KW; Bock-Hennig, BS1
Getova, D; Markovska, V1
Imaizumi, S; Kinouchi, H; Suzuki, J; Yoshimoto, T1
Addae, JI; Stone, TW1
Abe, K; Kogure, K1
Rock, DM; Taylor, CP1
Crawley, JN; Martin, JV; Mendelson, WB; Stivers, JA1
Devine, JE1
Bixler, TJ; Hollins, B; Mosteller, RC; Rudman, D1
Deitrich, RA; Erwin, VG1
Breese, GR; Mueller, RA; Smith, RD1
Lux, HD1
Cramer, JW; Whyatt, PL1
Greengard, P; Quinn, GP; Reid, MB1
Dauby, J; Evraerd, A; Giurgea, C; Moyersoons, F1
Kraft, D; Schaefer, K; von Herrath, D1
Brittain, RT1
Laycock, GM; Shulman, A1
Downes, H; Williams, JK1
Buchanan, AS; Laycock, GM; Shulman, A1
Mandel, HG; Riis, M1
Elison, C; Golden, M; Hussain, M; Lien, EJ; Tong, GL; Zinger, AP1
Carroll, D; Dzidic, I; Hill, RM; Horning, EC; Horning, MG; Lertratanangkoon, K; Nowlin, J; Stillwell, RN; Stillwell, WG1
Kamei, C; Shimomura, K; Ueki, S1
Kirsten, EB; Schoener, EP1
Henry, KR; Willott, J1
Morgan, WW; Reiter, RJ; Talbot, JA1
Somjen, GG; Strittmatter, WJ1
Gehres, LD; Randall, CL; Riccio, DC; Vardaris, RM1
Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A1
Kuenzel, WJ; Rubenstein, JB1
Neuvonen, PJ; Penttilä, O1
Somjen, GG1
Levy, SK; Schwartz, T1
Brendel, K; Bressler, R; Kizer, JS; Vargas-Gordon, M1
Remmer, H1
Halliday, J; Moir, AT1
Asahi, K; Iizuka, H; Okabe, Y; Yanagida, T1
von Albert, HH1
Smith, DE; Wesson, DR1
Clark, LD; Weinreich, D1
Downes, H; Karler, R; Ostlund, RE; Perry, RS1
Crawhall, JC; Itiaba, K; Sin, CM1
Keyl, AC; Nishie, K; Waiss, AC1
McCarty, LP; Standaert, FG; Zager, RF1
Glasson, B1
Dang, HC; Visek, WJ1
Blaustein, MP1
Bender, AD; Greene, L; Macko, E; Tedeschi, RE; Wilfon, G1
Sanders, HD1
Fromm, GH; Killian, JM1
Fathi, MM1
Nicoll, RA; Wojtowicz, JM1
Connors, BW1
Crosland, MB; Nosek, TM1
Greer, NL; Schechter, MD1
Hino, T; Ito, Y; Kunieda, T; Ohashi, H; Sakata, K; Tsuchiya, J1
Hillbom, ME; Hjelm-Jäger, M1
Al-Turk, W; Heinicke, RJ; Lemon, HM; Stohs, SJ1
Nemmer, J; Nemoto, EM; Shiu, GK1
Macdonald, RL; McLean, MJ1
Artru, AA; Michenfelder, JD2
Ikeda, H1
duSouich, P; Lalka, D; Ludden, TM; McLean, AJ; Vicuna, A; Vicuna, N1
Abe, J; Asada, A; Fujimori, M; Kaji, A; Nishi, S; Oda, Y; Yoshida, N1
Balster, RL; Evans, EB1
Mitchell, WG1
George, B; Kulkarni, SK1
Boothe, DM1
Boucher, BA; Hanes, SD1
Baumbarger, DO; Jones, M; Meyer, RE; Stoskopf, MK1
Brückner, C; Heinemann, U1
Akamatsu, N; Tsuji, S1
ASTON, R; DOMINO, EF1
NUTTER, DJ; STAPLE, PH1
HOAKEN, PC; KANE, FJ1
ABIKO, Y1
BOHNER, B; BRATTON, AC; CHEN, G1
ARENA, JM1
CORRIOL, J; FONDARAI, J; JOANNY, P1
GRANT, WM; PECZON, JD1
KUEHN, A; SCHALLEK, W; ZABRANSKY, F1
BHARGAVA, KP; BHATTACHARYA, SS; KISHOR, K; SAXENA, PN1
DUBOIS, KP; HIETBRINK, BE; YAM, KM1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1
FASMAN, GD; FOSTER, RJ; VAN HARREVELD, A1
Green, SL; McClure, DE; Torreilles, SL1
Gulati, S; Lodha, R; Raj, D1
Al-Khamees, WA; Algren, AD; Alrashdi, S; Morgan, BW; Schwartz, MD1
Bischoff, K; Ebel, JG; Jaeger, R1
Alvarez-Coca, J; Cantarín-Extremera, V; Castaño-De La Mota, C; Duat-Rodríguez, A; García Peñas, JJ; Gutierrez-Solana, LG; López-Marín, L; Losada-Del Pozo, R; Martínez-Pérez, J; Rojas, MR1
Alldredge, B; Bell, R; Bleck, TP; Brophy, GM; Claassen, J; Glauser, T; LaRoche, SM; Riviello, JJ; Shutter, L; Sperling, MR; Treiman, DM; Vespa, PM1
Hamlin, BC; McClure, PJ; Viner, TC; Yates, BC1
Forrester, MB1
Brice, AK; de Souza Dyer, C; Marx, JO1
Barletta, M; Hofmeister, EH; Peroni, JF; Quandt, JE; Scharf, AM; Thoresen, M1
Boivin, GP; Dudley, ES1
Bullock, JM; Lanaux, TM; Shmalberg, JW1
Allegaert, K; Yalcin, N1

Reviews

9 review(s) available for phenytoin and pentobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Conditions for the occurrence of drug interactions during biotransformation].
    Medizinische Klinik, 1979, Jan-19, Volume: 74, Issue:3

    Topics: Biotransformation; Dicumarol; Digitoxin; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Ethanol; Glucuronosyltransferase; Half-Life; Humans; Oxygenases; Pentobarbital; Phenytoin; Salicylates

1979
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
    AACN clinical issues in critical care nursing, 1991, Volume: 2, Issue:4

    Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Epilepsy; Humans; Pentobarbital; Phenobarbital; Phenytoin; Postoperative Complications; Seizures; Substance Withdrawal Syndrome

1991
Status epilepticus and acute repetitive seizures in children, adolescents, and young adults: etiology, outcome, and treatment.
    Epilepsia, 1996, Volume: 37 Suppl 1

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Benzodiazepines; Central Nervous System Diseases; Child; Diazepam; Epilepsia Partialis Continua; Epilepsy; Humans; Lorazepam; Midazolam; Middle Aged; Pentobarbital; Phenytoin; Recurrence; Seizures; Status Epilepticus; Treatment Outcome

1996
Anticonvulsant therapy in small animals.
    The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2

    Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid

1998
Pharmacokinetic alterations after severe head injury. Clinical relevance.
    Clinical pharmacokinetics, 1998, Volume: 35, Issue:3

    Topics: Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Blood-Brain Barrier; Craniocerebral Trauma; Drug Interactions; Humans; Hypnotics and Sedatives; Lorazepam; Pentobarbital; Phenytoin; Thiopental

1998
[Treatment of status epilepticus].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:12

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Electric Stimulation Therapy; Humans; Magnetics; Midazolam; Pentobarbital; Pentylenetetrazole; Phenytoin; Rats; Status Epilepticus

2001
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1964, Volume: 72

    Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents

1964
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:10

    Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid

2022

Trials

1 trial(s) available for phenytoin and pentobarbital

ArticleYear
Influence of sedation on onset and quality of euthanasia in sheep.
    Research in veterinary science, 2018, Volume: 117

    Topics: Animals; Anticonvulsants; Dexmedetomidine; Euthanasia, Animal; Female; Heart Rate; Hypnotics and Sedatives; Male; Pentobarbital; Phenytoin; Sheep

2018

Other Studies

119 other study(ies) available for phenytoin and pentobarbital

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
Mechanism of action of anticonvulsants. Role of the differential effects on the active uptake of putative neurotransmitters.
    Neurology, 1976, Volume: 26, Issue:2

    Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Hypnotics and Sedatives; In Vitro Techniques; Neurotransmitter Agents; Norepinephrine; Pentobarbital; Phenytoin; Rats

1976
Effect of liver microsome enzyme-inducing drugs on blood serum pentobarbital clearance and sleep time in sheep and rabbits.
    American journal of veterinary research, 1978, Volume: 39, Issue:4

    Topics: Animals; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenylbutazone; Phenytoin; Piperazines; Rabbits; Sheep; Sleep; Time Factors

1978
The effects of barbiturates on the metabolism of phosphatidic acid and phosphatidylinositol in rat brain synaptosomes.
    The Biochemical journal, 1979, Jan-15, Volume: 178, Issue:1

    Topics: Animals; Barbiturates; Brain; Calcium; Carbachol; Pentobarbital; Phenytoin; Phosphatidic Acids; Phosphatidylinositols; Phosphorus; Rats; Synaptosomes

1979
Interaction of phenytoin with chloramphenicol or pentobarbital in the dog.
    Journal of the American Veterinary Medical Association, 1979, Jul-15, Volume: 175, Issue:2

    Topics: Administration, Oral; Animals; Cerebellar Diseases; Chloramphenicol; Dog Diseases; Dogs; Drug Interactions; Female; Injections, Intravenous; Male; Pentobarbital; Phenytoin

1979
Evaluation of anticonvulsants in barbiturate withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Cats; Dimethadione; Female; Humans; Male; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Substance Withdrawal Syndrome; Time Factors; Trimethadione

1977
The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs.
    Epilepsia, 1977, Volume: 18, Issue:4

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Penicillin G; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Succinimides

1977
Modification of cardiovascular responses to intravenous phenytoin by dopamine in dogs: evidence against an adverse interaction.
    Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3

    Topics: Anesthesia; Animals; Blood Pressure; Dogs; Dopamine; Drug Interactions; Emetics; Female; Heart Rate; Hemodynamics; Male; Pentobarbital; Phenytoin; Time Factors

1978
Results of the use of a new water-soluble contrast medium (metrizamide) in the posterior fossa of the baboon.
    The British journal of radiology, 1975, Volume: 48, Issue:576

    Topics: Animals; Electrocardiography; Electroencephalography; Haplorhini; Injections, Intraventricular; Iodobenzoates; Metrizamide; Papio; Pentobarbital; Phenytoin; Seizures; Skull; Tomography, X-Ray

1975
Distribution of pentobarbital and diphenylhydantoin between plasma and cells in blood: effect of salicylic acid, temperature and total drug concentration.
    European journal of clinical pharmacology, 1977, Volume: 11, Issue:1

    Topics: Blood Cells; Blood Proteins; Drug Interactions; Humans; In Vitro Techniques; Osmolar Concentration; Pentobarbital; Phenytoin; Plasma; Protein Binding; Salicylates; Temperature

1977
Interaction of pentobarbital, diphenylhydantoin and digitoxin with ethanol in the isolated perfused guinea-pig liver.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:5

    Topics: Animals; Digitoxin; Drug Interactions; Ethanol; Guinea Pigs; In Vitro Techniques; Kinetics; Liver; Pentobarbital; Perfusion; Phenytoin

1976
Clinical applications of gas chromatograph/mass spectrometer/computer systems.
    Clinical chemistry, 1975, Volume: 21, Issue:9

    Topics: Autoanalysis; Caffeine; Chromatography, Gas; Computers; Diazepam; Evaluation Studies as Topic; Female; Humans; Imides; Indicators and Reagents; Mass Spectrometry; Methods; Milk, Human; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Theobromine; Time Factors

1975
CNS depressants: effects on post-synaptic pharmacology.
    Brain research, 1975, Jul-04, Volume: 92, Issue:1

    Topics: Acetylcholine; Animals; Astacoidea; Chloralose; Chlorides; Chloroform; Dopamine; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Glutamates; Membrane Potentials; Nephropidae; Neuromuscular Junction; Pentobarbital; Phenytoin; Potassium; Serotonin; Snails; Sodium; Synapses; Urethane; Vasopressins

1975
Biotransformation and biliary excretion of imipramine in rats under various experimental conditions.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 216, Issue:2

    Topics: Animals; Bile; Biliary Fistula; Biotransformation; Brain; Female; Imipramine; Injections, Intraperitoneal; Liver; Lung; Male; Pentobarbital; Phenytoin; Rats; Sex Factors; Subcellular Fractions; Time Factors

1975
Binding of amobarbital, pentobarbital and diphenylhydantoin to blood cells and plasma proteins in healthy volunteers and uraemic patients.
    European journal of clinical pharmacology, 1975, Aug-14, Volume: 8, Issue:6

    Topics: Adult; Aged; Amobarbital; Blood Proteins; Creatinine; Erythrocytes; Humans; In Vitro Techniques; Middle Aged; Pentobarbital; Phenytoin; Protein Binding; Serum Albumin; Uremia

1975
Chlordiazepoxide and diazepam induced mouse killing by rats.
    Psychopharmacologia, 1975, Oct-14, Volume: 44, Issue:1

    Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Mice; Parasympatholytics; Pentobarbital; Phenytoin; Pilocarpine; Predatory Behavior; Rats

1975
Effects of anticonvulsant drugs on axonal conduction in mammalian corpus callosum.
    Brain research, 1992, Jul-24, Volume: 586, Issue:2

    Topics: Action Potentials; Animals; Anticonvulsants; Axons; Corpus Callosum; Female; Guinea Pigs; In Vitro Techniques; Male; Neural Conduction; Pentobarbital; Phenobarbital; Phenytoin; Rats

1992
Interaction between GABAergic anticonvulsants and the NMDA receptor antagonist MK 801 against MES- and picrotoxin-induced convulsions in rats.
    Life sciences, 1989, Volume: 44, Issue:18

    Topics: Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Electroshock; Ethanol; Male; Motor Activity; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Stereotyped Behavior

1989
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers.
    Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23

    Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Induction; Female; Glucuronosyltransferase; Humans; Hydroquinones; Hymecromone; Isoenzymes; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Middle Aged; Naphthols; Pentobarbital; Phenytoin; Tumor Cells, Cultured

1987
Study of the participation of the dopaminergic transmission system in the effects of two newly synthesized barbiturates.
    Acta physiologica et pharmacologica Bulgarica, 1988, Volume: 14, Issue:2

    Topics: Animals; Apomorphine; Barbiturates; Catalepsy; Haloperidol; Male; Pentobarbital; Phenytoin; Rats; Receptors, Dopamine; Stereotyped Behavior; Synaptic Transmission

1988
[Superior protective activity of phenytoin against hypoxia in pharmacological screening test].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:2

    Topics: Animals; Atmosphere Exposure Chambers; Cerebral Infarction; Drug Evaluation, Preclinical; Hypoxia; Male; Mice; Pentobarbital; Phenytoin; Suloctidil; Vitamin E

1986
Effects of anticonvulsants on responses to excitatory amino acids applied topically to rat cerebral cortex.
    General pharmacology, 1988, Volume: 19, Issue:3

    Topics: Administration, Topical; Amino Acids; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Chlormethiazole; Diazepam; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains

1988
Prevention of an increase in susceptibility to calcium in a neuroblastoma cell line.
    Neuroscience letters, 1987, Oct-05, Volume: 80, Issue:3

    Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Cold Temperature; Flunarizine; Humans; Neuroblastoma; Pentobarbital; Phenytoin; Tumor Cells, Cultured

1987
Effects of diazepam, pentobarbital, phenytoin and pentylenetetrazol on hippocampal paired-pulse inhibition in vivo.
    Neuroscience letters, 1986, Apr-24, Volume: 65, Issue:3

    Topics: Action Potentials; Animals; Behavior, Animal; Diazepam; Electroshock; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraperitoneal; Male; Neural Inhibition; Pentobarbital; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains; Seizures

1986
Cholinergic induction of seizures in the rat prefrontal cortex.
    Life sciences, 1986, Jun-23, Volume: 38, Issue:25

    Topics: Animals; Carbachol; Cerebral Cortex; Clonazepam; Diazepam; Electroencephalography; Male; Microinjections; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior

1986
Assessment of the Corvac blood collection tube for drug specimen processing.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:2

    Topics: Blood Specimen Collection; Humans; Lidocaine; Pentobarbital; Pharmaceutical Preparations; Phenytoin; Quinidine; Theophylline; Time Factors

1986
Transport of drugs, hormones and fatty acids in lipemic serum.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:3

    Topics: Adult; Aldosterone; Animals; Biological Transport; Caprylates; Centrifugation; Chickens; Cholesterol; Dicumarol; Digitoxin; Digoxin; Estradiol; Fatty Acids; Hormones; Humans; Hydrocortisone; Hyperlipidemias; Male; Pentobarbital; Pharmaceutical Preparations; Phenytoin; Protein Binding; Rabbits; Salicylates; Testosterone

1972
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione

1973
Potentiation of drug-initiated adrenal tyrosine hydroxylase induction by diazepam.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 284, Issue:2

    Topics: Adrenal Glands; Animals; Biogenic Amines; Blood-Brain Barrier; Diazepam; Drug Synergism; Enzyme Induction; Hydroxydopamines; Insulin; Isoproterenol; Male; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Rats; Reserpine; Serotonin; Tyrosine 3-Monooxygenase

1974
Fast recording ion specific microelectrodes: their use in pharmacological studies in the CNS.
    Neuropharmacology, 1974, Volume: 13, Issue:6

    Topics: Acetylcholine; Animals; Bucladesine; Cats; Central Nervous System; Cerebral Cortex; Chlorides; Electric Conductivity; Electric Stimulation; Extracellular Space; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamates; Ion Exchange; Iontophoresis; Microelectrodes; Neurons; Norepinephrine; Pentobarbital; Phenytoin; Potassium; Potassium Chloride; Quaternary Ammonium Compounds; Tracheotomy

1974
Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells.
    Biochemical pharmacology, 1973, Jan-15, Volume: 22, Issue:2

    Topics: Animals; Barbiturates; Cell Line; Clone Cells; DNA, Neoplasm; Leucine; Leukemia, Experimental; Mast-Cell Sarcoma; Mice; Mitosis; Neoplasm Proteins; Pentobarbital; Phenytoin; RNA, Neoplasm; Sarcoma, Experimental; Structure-Activity Relationship; Succinimides; Thymidine; Tritium; Uridine

1973
Proceedings: Studies on the interference of 14C-pentobarbital, 14C-diphenylhydantoin and 3H-digitoxin with ethanol in the isolated perfused guinea-pig liver.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Bile; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Digitoxin; Ethanol; Guinea Pigs; Hydroxylation; Kinetics; Liver; Oxidation-Reduction; Pentobarbital; Phenytoin; Tritium

1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
A particular pharmacological effect on the propagation of experimental strychnine and penicillin epilepsy.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2

    Topics: Acetates; Animals; Anticonvulsants; Cerebral Cortex; Chlorpromazine; Electroencephalography; Electroshock; Female; Male; Penicillins; Pentobarbital; Phenobarbital; Phenytoin; Rabbits; Seizures; Sound; Strychnine; Synaptic Transmission

1969
Retarded growth of rats by anticonvulsant drugs.
    Epilepsia, 1974, Volume: 15, Issue:1

    Topics: Animals; Body Weight; Cholecalciferol; Dwarfism; Female; Growth; Maternal-Fetal Exchange; Pentobarbital; Phenytoin; Pregnancy; Rats; Time Factors

1974
Activity of CNS depressants related to hydrophobicity.
    Nature, 1974, Nov-01, Volume: 252, Issue:5478

    Topics: Action Potentials; Anesthesia, General; Anesthetics; Animals; Anticonvulsants; Axons; Chemical Phenomena; Chemistry; Chloralose; Chloroform; Depression, Chemical; Ethanol; Neural Conduction; Neurons; Pentobarbital; Phenytoin; Snails; Synapses; Synaptic Transmission; Urethane; Water

1974
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl

1966
Action of central nervous system stimulant and depressant drugs in the intact animal. 3. Dual action of 5-ethyl-5-(1,3-dimethylbutyl)barbiturate, dilantin and beta-methyl-beta-eta-propylglutarimide.
    European journal of pharmacology, 1967, Volume: 2, Issue:1

    Topics: Animals; Anticonvulsants; Barbiturates; Bemegride; Central Nervous System; Central Nervous System Stimulants; Depression, Chemical; Drug Antagonism; Hypnotics and Sedatives; Mice; Pentobarbital; Pentylenetetrazole; Phenytoin; Piperidines; Sensory Receptor Cells; Stimulation, Chemical; Trimethadione

1967
Effects of a convulsant barbiturate on the spinal monosynaptic pathway.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:2

    Topics: Animals; Barbiturates; Blood Pressure; Cats; Central Nervous System Stimulants; Lumbosacral Region; Pentobarbital; Phenytoin; Reflex; Reflex, Monosynaptic; Spinal Cord; Synapses; Trimethadione

1969
Action of central nervous system stimulant and depressant drugs in the intact animal. 4. Surface activity of drugs with central stimulant depressant, or dual stimulant-depressant action.
    European journal of pharmacology, 1969, Volume: 7, Issue:1

    Topics: Air; Amobarbital; Barbiturates; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Depression, Chemical; Glutarates; Hypnotics and Sedatives; Oxazines; Pentobarbital; Pentylenetetrazole; Phenytoin; Picrotoxin; Pregnanediones; Solutions; Stimulation, Chemical; Surface Properties; Surface Tension; Trimethadione

1969
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
CNS activities of lactam derivatives.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:7

    Topics: Amides; Animals; Anticonvulsants; Azocines; Butyrates; Central Nervous System; Central Nervous System Stimulants; Drug Interactions; Electroencephalography; Female; Heterocyclic Compounds; Ketones; Lactams; Lethal Dose 50; Male; Mice; Pentobarbital; Phenytoin; Respiration; Sleep; Structure-Activity Relationship; Time Factors

1971
The use of stable isotopes in gas chromatography-mass spectrometric studies of drug metabolism.
    Journal of chromatography, 1974, Apr-24, Volume: 91

    Topics: Amobarbital; Animals; Barbiturates; Body Fluids; Carbon Isotopes; Chromatography, Gas; Colostrum; Computers; Diazepam; Isotope Labeling; Mass Spectrometry; Microchemistry; Milk; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pressure; Secobarbital

1974
Significance of withdrawal jumping response in predicting physical dependence in mice.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:3

    Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imipramine; Male; Mephenesin; Methamphetamine; Mice; Morphine Dependence; Naloxone; Pentobarbital; Perphenazine; Phenytoin; Reserpine; Substance Withdrawal Syndrome

1973
Antagonism of pentylenetetrazol excitation by anticonvulsants on single brain stem neurons.
    Neuropharmacology, 1972, Volume: 11, Issue:4

    Topics: Animals; Anticonvulsants; Brain Stem; Cats; Decerebrate State; Diazepam; Drug Antagonism; In Vitro Techniques; Microelectrodes; Neurons; Pentobarbital; Pentylenetetrazole; Phenytoin; Stereotaxic Techniques; Time Factors; Trimethadione

1972
Effects of pharmacological agents on acoustic priming of audiogenic seizures.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2

    Topics: Acetates; Aminobutyrates; Animals; Brain Chemistry; Chlorpromazine; Hearing Loss, Noise-Induced; Mice; Mice, Inbred C57BL; Pentobarbital; Phenytoin; Seizures

1972
Seizures in rats induced by pinealectomy: influence of diazepam, chlordiazepoxide, diphenylhydantoin and pineal substances.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 202, Issue:2

    Topics: Animals; Calcium; Chlordiazepoxide; Diazepam; Gluconates; Indoles; Male; Melatonin; Parathyroid Glands; Pentobarbital; Phenytoin; Pineal Gland; Pyridines; Rats; Seizures; Time Factors; Tissue Extracts

1973
Depression of sustained evoked potentials and glial depolarization in the spinal cord by barbiturates and by diphenylhydantoin.
    Brain research, 1973, Jun-15, Volume: 55, Issue:2

    Topics: Animals; Cats; Electric Stimulation; Evoked Potentials; Extracellular Space; Membrane Potentials; Neuroglia; Pentobarbital; Phenytoin; Purkinje Cells; Spinal Cord; Thiopental

1973
Attenuation of hypothermic retrograde amnesia produced by pharmacologic blockage of brain seizures.
    Physiology & behavior, 1973, Volume: 10, Issue:6

    Topics: Amnesia; Amygdala; Animals; Avoidance Learning; Body Temperature; Cold Temperature; Electroencephalography; Hippocampus; Humans; Hypothermia; Immersion; Memory; Pentobarbital; Phenytoin; Rats; Seizures; Sodium Chloride; Solutions; Thiamylal

1973
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:12

    Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine

1973
Behavioral and physiological studies of a convulsing mutant chicken (Gallus domesticus).
    The Journal of experimental zoology, 1974, Volume: 187, Issue:1

    Topics: Acoustic Stimulation; Age Factors; Animals; Behavior, Animal; Body Temperature; Body Weight; Chickens; Electric Stimulation; Electroencephalography; Female; Genes, Lethal; Genes, Recessive; Mutation; Pentobarbital; Phenytoin; Photic Stimulation; Poultry Diseases; Rectum; Seizures; Sex Chromosomes

1974
Interaction between doxycycline and barbiturates.
    British medical journal, 1974, Mar-23, Volume: 1, Issue:5907

    Topics: Adult; Aged; Amobarbital; Barbiturates; Carbamazepine; Doxycycline; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Male; Middle Aged; Pentobarbital; Phenobarbital; Phenytoin

1974
Dynamic patterns of brain cell assemblies. IV. Mixed systems. Steady states and their shifts. Spinal cord studies.
    Neurosciences Research Program bulletin, 1974, Volume: 12, Issue:1

    Topics: Animals; Electric Stimulation; Electrophysiology; Neuroglia; Neurons; Pentobarbital; Phenytoin; Spinal Cord; Thiopental

1974
New mixed bed column for rapid gas-liquid chromatographic determination of sedatives and Dilantin in serum.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Jul-15, Volume: 54, Issue:1

    Topics: Amobarbital; Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Humans; Methods; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital; Time Factors

1974
The in vitro inhibition of insulin secretion by diphenylhydantoin.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:10

    Topics: Animals; Anticonvulsants; Buffers; Glucose; Hydantoins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methacholine Compounds; Ouabain; Pancreas; Pentobarbital; Phenytoin; Potassium; Rats; Tolbutamide

1970
[Changes of drug effects caused by their metabolism in the liver].
    Monatsschrift fur Kinderheilkunde, 1971, Volume: 119, Issue:7

    Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental

1971
Effect of drugs used in status-epilepticus on the potassium fluxes of cerebrospinal fluid in the conscious dog.
    British journal of pharmacology, 1971, Volume: 43, Issue:2

    Topics: Animals; Anticonvulsants; Diazepam; Dogs; Inulin; Paraldehyde; Pentobarbital; Phenytoin; Potassium; Potassium Isotopes; Thiopental

1971
[Influence of food deprivation on efficacy and toxicity of drugs in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, Mar-20, Volume: 65, Issue:2

    Topics: Acetates; Aminopyrine; Analgesics; Animals; Anticonvulsants; Blood Glucose; Blood Proteins; Body Weight; Carrageenan; Cholesterol; Citrates; Female; Male; Methylcellulose; Mice; Oxyphenbutazone; Pectins; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Starvation; Time Factors; Toxicology

1969
[Detection of sedative effect by electronystagmography].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:9

    Topics: Amphetamine; Antihypertensive Agents; Caffeine; Chlorpromazine; Dibenzazepines; Electric Stimulation; Humans; Hypnotics and Sedatives; Imidazoles; Methods; Pentobarbital; Phenmetrazine; Phenothiazines; Phenytoin; Promethazine; Thiethylperazine; Vestibular Function Tests

1969
A new method for treatment of barbiturate dependence.
    JAMA, 1970, Jul-13, Volume: 213, Issue:2

    Topics: Barbiturates; Chlordiazepoxide; Diazepam; Heroin; Humans; Meprobamate; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders

1970
Anticonvulsant drugs and self-stimulation rates in rats.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 185, Issue:2

    Topics: Acetazolamide; Animals; Chlordiazepoxide; Electrodes; Male; Meprobamate; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Placebos; Rats; Seizures; Self Stimulation

1970
A study of the excitatory effects of barbiturates.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:3

    Topics: Animals; Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Injections, Intravenous; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Trimethadione

1970
A rapid high resolution chromatographic method for serum barbiturates: instant thin-layer chromatography.
    Clinical biochemistry, 1970, Volume: 3, Issue:4

    Topics: Amobarbital; Ascitic Fluid; Barbiturates; Chromatography, Thin Layer; Humans; Mathematics; Methods; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital

1970
Toxicity of methylimidazoles.
    Toxicology and applied pharmacology, 1969, Volume: 14, Issue:2

    Topics: Animals; Anticonvulsants; Chickens; Chlordiazepoxide; Electroencephalography; Heart Rate; Imidazoles; Mice; Motor Activity; Pentobarbital; Pentylenetetrazole; Phenytoin; Pyrazines; Rabbits; Respiration; Respiratory Paralysis; Seizures

1969
The pharmacology of 2-aziridinyl ethanol.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:2

    Topics: Action Potentials; Animals; Atropine; Axons; Azirines; Cats; Chemical Phenomena; Chemistry; Ethanol; Ethyl Ethers; In Vitro Techniques; Muscle Contraction; Muscle Denervation; Muscles; Pentobarbital; Peripheral Nerves; Phenytoin; Rats; Tubocurarine

1969
[Services and perspectives of metabolic research on certain exogenous substances endowed with pharmacological activity].
    Bulletin de la Societe de chimie biologique, 1965, Volume: 47, Issue:5

    Topics: Animals; Carbon Tetrachloride Poisoning; Humans; Microsomes; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Proadifen; Rats; Substance-Related Disorders

1965
Antagonism of urease toxicity by chemical agents and antisera.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:2

    Topics: Alloxan; Animals; Anticonvulsants; Arginine; Barbiturates; Glutamates; Immune Sera; Injections, Intraperitoneal; Male; Mice; Pentobarbital; Phenobarbital; Phenytoin; Rats; Trimethadione; Urease

1966
Phospholipids as ion exchangers: implications for a possible role in biological membrane excitability and anesthesia.
    Biochimica et biophysica acta, 1967, Sep-09, Volume: 135, Issue:4

    Topics: Anesthesia; Binding Sites; Calcium; Chloroform; Hydrogen-Ion Concentration; Ion Exchange; Membranes, Artificial; Metals; Methanol; Models, Biological; Pentobarbital; Phenobarbital; Phenytoin; Phosphatidylethanolamines; Phospholipids; Procaine; Sulfhydryl Compounds

1967
Pharmacological properties of the isopropyl ester of o-sulfamoyl-benzoic acid.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Animals; Behavior, Animal; Benzoates; Carbamates; Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Dogs; Drug Antagonism; Electroshock; Male; Mephenesin; Meprobamate; Methocarbamol; Mice; Muscles; Pentobarbital; Phenethylamines; Phenobarbital; Phenytoin; Rats; Reflex; Seizures; Sleep; Strychnine; Trimethadione; Zoxazolamine

1967
A comparison of the convulsant activity of procaine and pentylenetetrazol.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 170, Issue:1

    Topics: Animals; Anticonvulsants; Chlorpromazine; Dibenzylchlorethamine; Female; Hydroxybutyrates; Mice; Pentobarbital; Pentylenetetrazole; Phenobarbital; Phenytoin; Procaine; Reflex; Reserpine; Seizures

1967
Effect of some anticonvulsant drugs on the spinal trigeminal nucleus.
    Neurology, 1967, Volume: 17, Issue:3

    Topics: Animals; Anticonvulsants; Blood Pressure; Body Temperature; Cats; Chloralose; Electric Stimulation; Electrophysiology; Imipramine; Maxillary Nerve; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Spinal Cord; Trigeminal Nerve

1967
Effect of drugs on brain acetylcholine level in Gerbillus pyramidum.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 74, Issue:1

    Topics: Acetylcholine; Animals; Behavior, Animal; Brain; Female; Gerbillinae; Male; Meprobamate; Methamphetamine; Morphine; Pentobarbital; Phenobarbital; Phenytoin; Reserpine

1983
The effects of pentobarbital and related compounds on frog motoneurons.
    Brain research, 1980, Jun-02, Volume: 191, Issue:1

    Topics: Amino Acids; Animals; Anura; Bicuculline; Chloralose; Chlordiazepoxide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Motor Neurons; Muscimol; Pentobarbital; Phenobarbital; Phenytoin; Picrotoxin; Spinal Cord; Strychnine; Synaptic Transmission

1980
A comparison of the effects of pentobarbital and diphenylhydantoin on the GABA sensitivity and excitability of adult sensory ganglion cells.
    Brain research, 1981, Mar-02, Volume: 207, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Pentobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Tetrodotoxin; Veratridine

1981
Calcium-dependent proteolysis in neural tissue is activated at physiologic intracellular Ca2+ levels and inhibited by some anticonvulsants.
    Journal of neurobiology, 1983, Volume: 14, Issue:1

    Topics: Animals; Anticonvulsants; Astacoidea; Brain; Calcium; Calpain; Caprylates; Endopeptidases; Pentobarbital; Phenytoin; Protease Inhibitors; Spinal Cord; Valproic Acid

1983
Phenytoin: similarity to tricyclic antidepressants.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:3

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chlordiazepoxide; Conditioning, Operant; Cues; Desipramine; Discrimination Learning; Imipramine; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains

1983
Stress ulcer accompanying subarachnoid hemorrhage--a new rat model.
    The Japanese journal of surgery, 1983, Volume: 13, Issue:4

    Topics: Animals; Cimetidine; Diazepam; Disease Models, Animal; Gastric Mucosa; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Subarachnoid Hemorrhage

1983
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:1

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazole; Female; Humans; Male; Middle Aged; Oxazepam; Pentobarbital; Phenytoin; Psychoses, Alcoholic; Seizures; Substance Withdrawal Syndrome

1984
Chronic phenytoin administration and the hepatic mixed function oxidase system in female rats.
    General pharmacology, 1984, Volume: 15, Issue:2

    Topics: Animals; Enzyme Induction; Female; Intestines; Lung; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Sleep; Time Factors

1984
Dose of thiopental, pentobarbital, and phenytoin for maximal therapeutic effects in cerebral ischemic anoxia.
    Critical care medicine, 1983, Volume: 11, Issue:6

    Topics: Animals; Brain Chemistry; Brain Ischemia; Fatty Acids, Nonesterified; Female; Hypoxia, Brain; Ketamine; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiopental

1983
Cellular bases of barbiturate and phenytoin anticonvulsant drug action.
    Epilepsia, 1982, Volume: 23 Suppl 1

    Topics: Animals; Barbiturates; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Neurons; Pentobarbital; Phenobarbital; Phenytoin; Synapses

1982
Anoxic cerebral potassium accumulation reduced by phenytoin: mechanism of cerebral protection?
    Anesthesia and analgesia, 1981, Volume: 60, Issue:1

    Topics: Animals; Cisterna Magna; Dose-Response Relationship, Drug; Heart Arrest; Hypothermia, Induced; Hypoxia, Brain; Pentobarbital; Phenytoin; Potassium; Rabbits

1981
Influence of hypothermia or hyperthermia alone or in combination with pentobarbital or phenytoin on survival time in hypoxic mice.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:12

    Topics: Animals; Body Temperature; Brain; Energy Metabolism; Hypothermia, Induced; Hypoxia; Lactates; Lactic Acid; Male; Mice; Mice, Inbred ICR; Oxygen Consumption; Pentobarbital; Phenytoin; Phosphocreatine; Time Factors

1981
[Pharmacological studies on the functional development of the central nervous system in first generation rats born to phenytoin-treated mothers (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:1

    Topics: Animals; Animals, Newborn; Ataxia; Birth Rate; Brain; Catalepsy; Diazepam; Eye; Feeding Behavior; Female; Haloperidol; Humans; Male; Pentobarbital; Phenytoin; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Sleep

1982
Dose-dependence of the apparent half-life of phenytoin in the rat.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:1

    Topics: Anesthesia; Animals; Biotransformation; Dose-Response Relationship, Drug; Half-Life; Kinetics; Pentobarbital; Phencyclidine; Phenytoin; Rats

1980
Effect of barbiturate therapy on phenytoin pharmacokinetics.
    Critical care medicine, 1993, Volume: 21, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Epilepsy; Female; Humans; Intracranial Pressure; Male; Middle Aged; Pentobarbital; Phenytoin; Prospective Studies

1993
Inhaled 1,1,1-trichloroethane-produced physical dependence in mice: effects of drugs and vapors on withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Administration, Inhalation; Animals; Chlorpromazine; Ethanol; Male; Mice; Midazolam; Pentobarbital; Phenytoin; Substance Withdrawal Syndrome; Substance-Related Disorders; Toluene; Trichloroethanes; Volatilization

1993
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid

1996
Field immobilization and euthanasia of American opossum.
    Journal of wildlife diseases, 1999, Volume: 35, Issue:1

    Topics: Analgesics; Anesthetics; Animal Welfare; Animals; Butorphanol; Drug Combinations; Euthanasia; Female; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Muscle Relaxants, Central; Opossums; Pentobarbital; Phenytoin; Tiletamine; Zolazepam

1999
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
    Brain research, 2000, Mar-17, Volume: 859, Issue:1

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid

2000
Differential effects of phenobarbital, pentobarbital and diphenylhydantoin on motor cortical and reticular thresholds in the rhesus monkey.
    Psychopharmacologia, 1961, Volume: 2

    Topics: Animals; Cerebral Cortex; Humans; Hydantoins; Macaca mulatta; Mesencephalon; Pentobarbital; Phenobarbital; Phenytoin

1961
Antagonism of pentobarbitone anaesthesia in hamsters by 5,5-diphenylhydantoin modified by salicylate.
    Nature, 1962, Jun-09, Volume: 194

    Topics: Anesthesia; Anesthesiology; Hydantoins; Pentobarbital; Phenytoin; Salicylates

1962
Unusual brain syndrome seen with diphenylhydantoin and pentobarbital.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Brain; Brain Diseases; Humans; Pentobarbital; Phenytoin

1963
[Effect of diphenylhydantoin on the toxicity and heart action of strospeside in cats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1962, Jul-20, Volume: 58

    Topics: Anesthetics, General; Animals; Bradycardia; Cardiac Glycosides; Cats; Ethers; Heart; Pentobarbital; Phenytoin

1962
The influence of certain central depressants on fighting behavior of mice.
    Archives internationales de pharmacodynamie et de therapie, 1963, Mar-01, Volume: 142

    Topics: Animals; Behavior; Central Nervous System Agents; Chloral Hydrate; Chlorpromazine; Hypnotics and Sedatives; Meprobamate; Mice; Pentobarbital; Phenobarbital; Phenytoin; Reserpine

1963
TREATMENT OF CONVULSIONS.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Amobarbital; Anticonvulsants; Ethanol; Humans; Paraldehyde; Pentobarbital; Phenytoin; Seizures; Succinylcholine; Thiopental

1964
[ACTION OF VARIOUS UREIDES ON K GRADIENTS OF MAMMALIAN CEREBRAL TISSUE ELECTRICALLY STIMULATED IN VITRO].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1963, Volume: 157

    Topics: Anticonvulsants; Barbiturates; Brain; Electrophysiological Phenomena; Electrophysiology; Guinea Pigs; Hydantoins; Hypnotics and Sedatives; In Vitro Techniques; Metabolism; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Potassium; Research; Urea

1963
EFFECTS OF BENZODIAZEPINES ON CENTRAL NERVOUS SYSTEM OF CAT.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Anticonvulsants; Benzodiazepines; Brain; Carbamates; Carisoprodol; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Decerebrate State; Hypothalamus; Limbic System; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Research; Thalamus; Tranquilizing Agents

1964
A NEUROPHARMACOLOGICAL STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA).
    Archives internationales de pharmacodynamie et de therapie, 1964, Aug-01, Volume: 150

    Topics: Aminobutyrates; Anesthesia; Anesthesia, Intravenous; Behavior, Animal; Brain Chemistry; Cats; Chlorpromazine; Electroencephalography; Electroshock; gamma-Aminobutyric Acid; Hydroxylamines; Metabolism; Neuropharmacology; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Research; Reserpine; Seizures; Strychnine; Toxicology

1964
PHARMACOLOGICAL AND TOXICOLOGICAL COMPOUNDS AS PROTECTIVE OR THERAPEUTIC AGENTS AGAINST RADIATION INJURY IN EXPERIMENTAL ANIMALS. 3. STUDIES ON THE TOXICITY AND MECHANISM OF ACTION OF MERCAPTOETHYLAMINE (MEA). QUART PROGR REP NO. 53.
    Quarterly progress report. United States. Air Force. Radiation Laboratory, University of Chicago, 1964, Oct-15, Volume: 53

    Topics: Animals; Animals, Laboratory; Cysteamine; Cysteine; Diphenhydramine; Glutathione; Guinea Pigs; Mercaptoethylamines; Pentobarbital; Pharmacology; Phenytoin; Radiation Effects; Radiation Injuries; Radiation-Protective Agents; Rats; Research; Reserpine; Toxicology; Tripelennamine

1964
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine

1965
Effect of diphenyl hydantoin (Dilantin) on ether and pentobarbital (Nembutal) narcosis.
    The American journal of physiology, 1951, Volume: 166, Issue:3

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Biphenyl Compounds; Ether; Humans; Hydantoins; Pentobarbital; Phenytoin; Stupor

1951
Evaluation and refinement of euthanasia methods for Xenopus laevis.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2009, Volume: 48, Issue:5

    Topics: Aminobenzoates; Animals; Benzocaine; Euthanasia, Animal; Pentobarbital; Phenytoin; Time Factors; Unconsciousness; Xenopus laevis

2009
Status epilepticus.
    Indian journal of pediatrics, 2011, Volume: 78, Issue:2

    Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid

2011
Status epilepticus associated with borage oil ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:2

    Topics: Acyclovir; Adult; Anticonvulsants; Borago; Diethylcarbamazine; Drug Therapy, Combination; Female; gamma-Linolenic Acid; Humans; Lorazepam; Pentobarbital; Phenytoin; Plant Oils; Seizures; Status Epilepticus; Treatment Outcome

2011
An unusual case of relay pentobarbital toxicosis in a dog.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:3

    Topics: Adipose Tissue; Animals; Anticonvulsants; Coma; Dog Diseases; Dogs; Female; Gas Chromatography-Mass Spectrometry; Hypnotics and Sedatives; Oxygen Inhalation Therapy; Pentobarbital; Phenytoin; Whales

2011
Procalcitonin, a high acute phase reactant in antiepileptic hypersentivity syndrome in pediatric age.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2012, Volume: 16, Issue:2

    Topics: Adolescent; Anticonvulsants; Calcitonin; Calcitonin Gene-Related Peptide; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Epilepsy, Frontal Lobe; Epstein-Barr Virus Infections; Female; Humans; Male; Pentobarbital; Phenytoin; Protein Precursors; Transaminases

2012
Treatment of status epilepticus: an international survey of experts.
    Neurocritical care, 2013, Volume: 18, Issue:2

    Topics: Administration, Intravenous; Adult; Anticonvulsants; Child; Consensus; Expert Testimony; Humans; Hypnotics and Sedatives; Levetiracetam; Lorazepam; Midazolam; Pentobarbital; Phenytoin; Piracetam; Propofol; Societies, Medical; Status Epilepticus; Surveys and Questionnaires; Valproic Acid

2013
Integrating the Forensic Sciences in Wildlife Case Investigations: A Case Report of Pentobarbital and Phenytoin Toxicosis in a Bald Eagle (Haliaeetus leucocephalus).
    Veterinary pathology, 2016, Volume: 53, Issue:5

    Topics: Animals; Animals, Wild; Cats; Eagles; Fatal Outcome; Forensic Pathology; Pathology, Veterinary; Pentobarbital; Phenytoin

2016
Human exposures to pentobarbital-phenytoin combination veterinary drugs.
    Human & experimental toxicology, 2017, Volume: 36, Issue:7

    Topics: Adolescent; Adult; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Pentobarbital; Phenytoin; Poison Control Centers; Texas; Veterinary Drugs; Young Adult

2017
Intraperitoneal Administration of Ethanol as a Means of Euthanasia for Neonatal Mice (
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2017, May-01, Volume: 56, Issue:3

    Topics: Animal Welfare; Animals; Animals, Newborn; Ethanol; Euthanasia, Animal; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Pentobarbital; Phenytoin; Unconsciousness

2017
Evaluation of a Commercially Available Euthanasia Solution as a Voluntarily Ingested Euthanasia Agent in Laboratory Mice.
    Journal of the American Association for Laboratory Animal Science : JAALAS, 2018, 01-01, Volume: 57, Issue:1

    Topics: Administration, Oral; Animals; Euthanasia, Animal; Female; Laboratory Animal Science; Male; Mice; Pain; Pentobarbital; Phenytoin

2018
Comparison of pentobarbital-phenytoin alone vs propofol prior to pentobarbital-phenytoin for euthanasia in 436 client-owned dogs.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2019, Volume: 29, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Dogs; Drug Therapy, Combination; Euthanasia, Animal; Female; Incidence; Male; Pentobarbital; Phenytoin; Propofol; Prospective Studies; Spasm; Texas

2019