phenytoin and penicillin g

phenytoin has been researched along with penicillin g in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199022 (64.71)18.7374
1990's1 (2.94)18.2507
2000's4 (11.76)29.6817
2010's7 (20.59)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lothman, EW; Somjen, GG1
Asboe-Hansen, G2
Layzer, RB; Porter, RJ2
Gartside, IB1
Frigyesi, TL; Lombardini, JB1
Hoffer, BJ; Oliver, AP; Wyatt, RJ1
Höffler, D; Köhler, H; Krieglstein, J; Rieger, H; Voigt, R; Weihrauch, TR1
Bender, AD; Higson, JE; Meier, JP; Post, A; Reichard, G1
Höffler, D; Köhler, H; Krieglstein, J; Rieger, H; Weihrauch, TR1
Craig, WA; Evenson, MA; Sarver, KP; Wagnild, JP1
Abendroth, K; Müller, W1
Gerald, MC; Massey, J; Spadaro, DC1
Edmonds, HL; Hollinger, MA; Stark, LG1
Oldendorf, WH1
Schulz, KH1
Edmonds, HL; Keesling, P; Stark, LG1
Love, DW; Salter, FJ1
Agurell, S; Boréus, LO; Ehrnebo, M; Jalling, B1
Kutt, H; Louis, S; McDowell, F1
Bustamante, L; Goldensohn, ES; Lueders, H; Pippenger, C1
Almirante, B; Campos, L; Cortés, E; del Valle, O; Gasser, I; Pahissa, A; Pigrau, C1
Xu, H; Yu, Z1
Kleinjans, JC; Pennings, JL; Piersma, AH; Robinson, JF; Theunissen, PT; van Herwijnen, MH1

Reviews

1 review(s) available for phenytoin and penicillin g

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

33 other study(ies) available for phenytoin and penicillin g

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Motor and electrical signs of epileptiform activity induced by penicillin in the spinal cords of decapitate cats.
    Electroencephalography and clinical neurophysiology, 1976, Volume: 41, Issue:3

    Topics: Animals; Blood Pressure; Cats; Chloralose; Decerebrate State; Dose-Response Relationship, Drug; Penicillin G; Penicillinase; Peripheral Nerves; Phenobarbital; Phenytoin; Seizures; Spinal Cord; Spinal Nerve Roots

1976
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1979
Plasma albumin concentration and diphenylhydantoin binding in man.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Protein Electrophoresis; Blood-Brain Barrier; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Radioligand Assay; Serum Albumin; Ultrafiltration; Uremia

1975
The actions of diazepam and phenytoin on a low dose penicillin epileptiform focus in the anaesthetised rat.
    British journal of pharmacology, 1978, Volume: 62, Issue:2

    Topics: Animals; Diazepam; Electroencephalography; Epilepsies, Partial; Penicillin G; Phenytoin; Rats

1978
Augmentation of thalamo - motor cortico - cerebellar epileptogenesis by taurine and its antagonism by diphenylhydantoin.
    Life sciences, 1979, Apr-02, Volume: 24, Issue:14

    Topics: Animals; Cats; Cerebellum; Electric Stimulation; Motor Cortex; Penicillin G; Phenytoin; Purkinje Cells; Seizures; Taurine; Thalamus; Time Factors

1979
The hippocampal slice: a system for studying the pharmacology of seizures and for screening anticonvulsant drugs.
    Epilepsia, 1977, Volume: 18, Issue:4

    Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Penicillin G; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Succinimides

1977
[Influence of diazepam and phenytoin on penicillin-induced cerebral convulsions (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:3

    Topics: Animals; Diazepam; Electroencephalography; Penicillin G; Phenytoin; Rabbits; Seizures

1976
Plasma protein binding of drugs as a function of age in adult human subjects.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:10

    Topics: Adult; Aged; Aging; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Blood Proteins; Blood Urea Nitrogen; Humans; In Vitro Techniques; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Serum Globulins

1975
[Effect of diazepam and phenytoin on penicillin-induced convulsions].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1975, Volume: 81

    Topics: Animals; Diazepam; Penicillin G; Phenytoin; Rabbits; Seizures

1975
Correction of protein binding defect in uremic sera by charcoal treatment.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:4

    Topics: Blood Proteins; Charcoal; Dicloxacillin; Digitoxin; Fatty Acids, Nonesterified; Humans; In Vitro Techniques; Penicillin G; Phenytoin; Protein Binding; Renal Dialysis; Salicylates; Serum Albumin; Sulfamethoxazole; Uremia

1976
[Therapeutic conclusions from the immunologic events in agranulocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, Sep-01, Volume: 27, Issue:17

    Topics: Adult; Aged; Agranulocytosis; Ampicillin; Antifungal Agents; Barbiturates; Blood Transfusion; Bone Marrow Diseases; Colistin; Female; gamma-Globulins; Humans; Immunity, Active; Leukocyte Count; Male; Middle Aged; Neomycin; Oxytetracycline; Penicillin G; Pertussis Vaccine; Phenytoin; Prednisolone

1972
Comparative convulsant activity of various penicillins after intracerebral injection in mice.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:2

    Topics: Ampicillin; Animals; Cephaloridine; Drug Synergism; Hydrogen-Ion Concentration; Injections; Male; Methicillin; Mice; Penicillin G; Penicillin V; Penicillinase; Penicillins; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Seizures; Sodium

1973
The effects of diphenylhydantoin, phenobarbital, and diazepam on the penicillin-induced epileptogenic focus in the rat.
    Experimental neurology, 1974, Volume: 45, Issue:2

    Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsies, Partial; Male; Penicillin G; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Scintillation Counting; Seizures

1974
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
Plasma albumin concentration and binding of diphenylhydantoin in man.
    Transactions of the American Neurological Association, 1974, Volume: 99

    Topics: Adolescent; Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin

1974
[Lymphocyte transformation test in drug hypersensitivity].
    Archiv fur dermatologische Forschung, 1972, Volume: 244

    Topics: Ampicillin; Drug Hypersensitivity; Exanthema; Humans; Immunologic Techniques; Lymphocyte Activation; Penicillin G; Penicillins; Phenylbutazone; Phenytoin; Stevens-Johnson Syndrome; Sulfanilamides; Trimethoprim

1972
Penicillin-induced epileptogenic foci. I. Time course and the anticonvulsant effects of diphenylhydantoin and diazepam.
    Neuropharmacology, 1974, Volume: 13, Issue:4

    Topics: Animals; Anticonvulsants; Cats; Cerebral Cortex; Cerebral Ventricles; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrodes, Implanted; Electroencephalography; Epilepsy; Injections; Male; Penicillin G; Phenytoin; Stereotaxic Techniques; Time Factors

1974
Suspected neurotoxicity from intravenous penicillin: a patient case.
    American journal of hospital pharmacy, 1972, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Ampicillin; Blood Urea Nitrogen; Chronic Disease; Creatine; Diazepam; Gentamicins; Humans; Injections, Intravenous; Male; Methicillin; Middle Aged; Penicillin G; Phenytoin; Pneumonia; Seizures; Time Factors

1972
Age differences in drug binding by plasma proteins: studies on human foetuses, neonates and adults.
    European journal of clinical pharmacology, 1971, Volume: 3, Issue:4

    Topics: Adult; Age Factors; Aging; Ampicillin; Azides; Bilirubin; Blood Proteins; Dialysis; Female; Fetus; Freezing; Gestational Age; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Infant, Newborn; Maternal-Fetal Exchange; Penicillin G; Phenobarbital; Phenytoin; Pregnancy; Protein Binding; Sulfur Isotopes

1971
Intravenous diphenylhydantoin in experimental seizures. II. Effect on penicillin-induced seizures in the cat.
    Archives of neurology, 1968, Volume: 18, Issue:5

    Topics: Animals; Blood Pressure; Cats; Electroencephalography; Electrophysiology; Injections, Intravenous; Neurons; Penicillin G; Phenytoin; Seizures

1968
The effects of phenytoin on the penicillin-induced spike focus.
    Electroencephalography and clinical neurophysiology, 1980, Volume: 48, Issue:1

    Topics: Animals; Cats; Cerebral Cortex; Electroencephalography; Evoked Potentials; Penicillin G; Phenytoin; Seizures

1980
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1982
[Treatment and outcome of pneumococcal meningitis in adults. Study of a recent series of 70 episodes].
    Medicina clinica, 1995, Nov-25, Volume: 105, Issue:18

    Topics: Adult; Age Factors; Aged; Anticonvulsants; Cephalosporins; Dexamethasone; Diuretics, Osmotic; Female; Glucocorticoids; Humans; Male; Mannitol; Meningitis, Pneumococcal; Middle Aged; Penicillin G; Penicillins; Phenytoin; Time Factors

1995
[Establishment of embryonic stem cell for evaluation of development neurotoxicity and test the validation of embryonic stem cell].
    Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:6

    Topics: Animal Testing Alternatives; Animals; BALB 3T3 Cells; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Fluorouracil; Mice; Neurons; Penicillin G; Phenytoin; Reproducibility of Results; Toxicity Tests; Tretinoin

2010
Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).
    Toxicology and applied pharmacology, 2012, Aug-01, Volume: 262, Issue:3

    Topics: Acetaldehyde; Animals; Carbamazepine; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation; In Vitro Techniques; Mice; Neural Stem Cells; Neurites; Penicillin G; Phenytoin; Silanes; Toxicity Tests; Triazoles

2012