phenytoin and oxcarbazepine

phenytoin has been researched along with oxcarbazepine in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (18.18)18.2507
2000's15 (22.73)29.6817
2010's28 (42.42)24.3611
2020's11 (16.67)2.80

Authors

AuthorsStudies
Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Aikiä, M; Halonen, T; Kälviäinen, R; Riekkinen, PJ; Sivenius, J1
Patsalos, PN; Zakrzewska, JM1
Breckenridge, AM; Chadwick, D; Graham, A; Park, BK; Pirmohamed, M; Roberts, P; Smith, D1
Eadie, MJ1
Elyas, AA; Patsalos, PN; Zakrzewska, JM1
Blacklaw, J; Brodie, MJ; Connelly, D; Forrest, G; Gillham, RA; McKee, PJ; Walker, SM1
Avanzini, G; Battino, D; Estienne, M1
Gram, L; Rogvi-Hansen, B1
Bill, PA; Guerreiro, CA; Kochen, S; Moore, A; Pohlmann, H; Saffer, D; Vigonius, U1
Antoniuk, SA; de Manreza, ML; Fejerman, N; Guerreiro, MM; Moore, A; Pohlmann, H; Vigonius, U1
Brodie, MJ1
Tecoma, ES1
Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D1
Kalhorn, TF; Lakehal, F; Levy, RH; Wurden, CJ1
Rekling, JC1
Bergin, AM; Connolly, M1
Kalita, J; Misra, UK; Rathore, C1
Bang, LM; Goa, KL1
Yatham, LN1
Oken, BS; Salinsky, MC; Spencer, DC; Storzbach, D1
Marson, AG; Muller, M; Williamson, PR1
Bóné, B; Janszky, J1
Edelbroek, PM; Vermeij, TA1
Abou-Khalil, BW; Azar, NJ; Song, Y; Wang, L1
Abou-Khalil, BW; Azar, NJ; Song, Y; Wang, L; Wright, AT1
Kan, L; Levy, AS; Maytal, J; Shinnar, S; Sogawa, Y1
Chen, CH; Chen, YT; Chu, CY; Chung, WH; Hsih, MS; Hui, RC; Hung, SI; Liu, ZS1
Arif, H; Bazil, CW; Buchsbaum, R; Hirsch, LJ; Pierro, J; Resor, SR; Sims, J; Whalen, M1
Akiyama, T; Otsubo, H1
Kim, SE; Kim, SH; Kwon, OY; No, SK; Park, KM1
Dahlin, MG; Ohman, I; Wide, K1
Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F1
Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M1
Malik, AK; Rani, S; Singh, B1
Malik, AK; Rani, S1
Marson, AG; Muller, M; Nolan, SJ; Tudur Smith, C1
Lang, LM; Linnet, K1
Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM1
Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Francisco, J; Oliveira, P; Rodrigues, M; Rosado, L; Rosado, P1
Abou-Khalil, BW1
Bae, EK; Jang, IJ; Kim, TJ; Lee, J; Lee, KJ; Lee, SK; Moon, J; Shin, D; Shin, JW; Shin, YW1
Bártfai, G; Devosa, I; Szok, D; Vanya, M1
Hsieh, CY; Huang, CW; Lai, EC; Lin, SJ; Setoguchi, S; Su, CC; Yang, YK1
Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J2
Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C1
Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F1
Marson, AG; Nevitt, SJ; Tudur Smith, C1
Abbott, J; Bendtsen, L; Braschinsky, M; Cruccu, G; Di Stefano, G; Donnet, A; Eide, PK; Jensen, TS; Leal, PRL; Maarbjerg, S; May, A; Nurmikko, T; Obermann, M; Zakrzewska, JM1
Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ1
Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Meirinho, S; Rodrigues, M1
A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV1
Bien, CG; Brandt, C; Hagemann, A; Klimpel, D; May, TW1
Bridgewater, B; Feng, S; McIntire, G; Strickland, EC1
Bingaman, W; Ferguson, L; Ghosh, A; Ghosh, C; Hossain, M; Najm, IM; Williams, S1
Ahn, KM; Chung, SJ; Oh, JH; Park, HW; Shim, JS1
Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R1
Agrawal, M; Dhurandhar, Y; Panda, SP1
Allegaert, K; Yalcin, N1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1
Bettinotti, M; Boldt, ABW; de Paola, L; Glehn, CQCV; Silvado, CES; Spina Tensini, T1

Reviews

23 review(s) available for phenytoin and oxcarbazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drugs used in the management of trigeminal neuralgia.
    Oral surgery, oral medicine, and oral pathology, 1992, Volume: 74, Issue:4

    Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia; Valproic Acid

1992
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
    Clinical pharmacokinetics, 1991, Volume: 21, Issue:1

    Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid

1991
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate.
    Clinical pharmacokinetics, 1995, Volume: 29, Issue:5

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenytoin; Thiazines; Triazines; Vigabatrin

1995
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
    Pharmacology & therapeutics, 1995, Volume: 68, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Nervous System Diseases; Oxcarbazepine; Phenobarbital; Phenytoin; Sleep Stages; Vigabatrin

1995
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin

1999
Oxcarbazepine.
    Epilepsia, 1999, Volume: 40 Suppl 5

    Topics: Adult; Animals; Anticonvulsants; Biological Availability; Biotransformation; Carbamazepine; Controlled Clinical Trials as Topic; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Epilepsy; Humans; Oxcarbazepine; Phenytoin; Treatment Outcome

1999
New antiepileptic drug therapies.
    Neurologic clinics, 2002, Volume: 20, Issue:4

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide

2002
Phenytoin and carbamazepine cross reactivity: report of a case and review of literature.
    Postgraduate medical journal, 2003, Volume: 79, Issue:938

    Topics: Anticonvulsants; Carbamazepine; Child; Drug Eruptions; Drug Interactions; Humans; Male; Oral Ulcer; Oxcarbazepine; Phenytoin; Seizures

2003
Newer anticonvulsants in the treatment of bipolar disorder.
    The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10

    Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2004
Oxcarbazepine versus phenytoin monotherapy for epilepsy.
    The Cochrane database of systematic reviews, 2006, Apr-19, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Oxcarbazepine; Phenytoin; Randomized Controlled Trials as Topic; Remission Induction

2006
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].
    Ideggyogyaszati szemle, 2006, May-20, Volume: 59, Issue:5-6

    Topics: Androgens; Anticonvulsants; Bromocriptine; Carbamazepine; Cognition; Enzyme Induction; Epilepsy; Gonadal Steroid Hormones; Humans; Lamotrigine; Liver; Male; Oxcarbazepine; Phenytoin; Sexual Dysfunctions, Psychological; Testosterone; Triazines; Valproic Acid

2006
[Antiepileptic drugs in North America].
    Brain and nerve = Shinkei kenkyu no shinpo, 2010, Volume: 62, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Drug Approval; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Lorazepam; North America; Phenytoin; Piracetam; Topiramate; Triazines

2010
Oxcarbazepine versus phenytoin monotherapy for epilepsy.
    The Cochrane database of systematic reviews, 2013, May-31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Induction Chemotherapy; Oxcarbazepine; Phenytoin; Randomized Controlled Trials as Topic

2013
Antiepileptic Drugs.
    Continuum (Minneapolis, Minn.), 2016, Volume: 22, Issue:1 Epilepsy

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Seizures; Triazines

2016
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
    Orvosi hetilap, 2016, Apr-10, Volume: 157, Issue:15

    Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid

2016
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide

2017
Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2018, 10-23, Volume: 10

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Induction Chemotherapy; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Randomized Controlled Trials as Topic; Treatment Failure

2018
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:9

    Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid

2022
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
    Mitochondrion, 2022, Volume: 66

    Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid

2022
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:10

    Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid

2022
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022

Trials

6 trial(s) available for phenytoin and oxcarbazepine

ArticleYear
Cognitive effects of oxcarbazepine and phenytoin monotherapy in newly diagnosed epilepsy: one year follow-up.
    Epilepsy research, 1992, Volume: 11, Issue:3

    Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Cognition; Double-Blind Method; Epilepsy; Female; Humans; Male; Memory; Oxcarbazepine; Phenytoin; Psychomotor Performance

1992
A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin; Valproic Acid

1994
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy.
    Epilepsy research, 1997, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin

1997
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy.
    Epilepsy research, 1997, Volume: 27, Issue:3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Double-Blind Method; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Oxcarbazepine; Phenytoin

1997
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 7

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin

2000
Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteers.
    Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Affect; Anticonvulsants; Carbamazepine; Cognition; Double-Blind Method; Electroencephalography; Humans; Middle Aged; Neuropsychological Tests; Oxcarbazepine; Phenytoin; Psychomotor Performance; Reaction Time; Regression Analysis

2004

Other Studies

37 other study(ies) available for phenytoin and oxcarbazepine

ArticleYear
Inhibition of aquaporin 4 by antiepileptic drugs.
    Bioorganic & medicinal chemistry, 2009, Jan-01, Volume: 17, Issue:1

    Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cell Death; Drug Hypersensitivity; Female; Humans; Male; Microsomes, Liver; Middle Aged; Oxcarbazepine; Phenytoin

1991
Dose dependent enzyme induction by oxcarbazepine?
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:2

    Topics: Aged; Anticonvulsants; Antipyrine; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Liver; Male; Middle Aged; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia

1990
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19.
    Epilepsy research, 2002, Volume: 52, Issue:2

    Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chlorophyll; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Mephenytoin; Microsomes; Mixed Function Oxygenases; Oxcarbazepine; Phenytoin; Recombinant Proteins

2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid

2003
Spotlight on oxcarbazepine in epilepsy.
    CNS drugs, 2004, Volume: 18, Issue:1

    Topics: Adolescent; Anticonvulsants; Area Under Curve; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cytochromes; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Male; Oxcarbazepine; Phenytoin

2004
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Sep-15, Volume: 857, Issue:1

    Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide

2007
Temporal pattern of oxcarbazepine and phenytoin withdrawal seizures during epilepsy monitoring.
    Epilepsy research, 2008, Volume: 79, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Electroencephalography; Epilepsy; Female; Humans; Male; Monitoring, Physiologic; Oxcarbazepine; Phenytoin; Poisson Distribution; Retrospective Studies; Seizures; Substance Withdrawal Syndrome

2008
Generalized tonic-clonic seizures after acute oxcarbazepine withdrawal.
    Neurology, 2008, May-27, Volume: 70, Issue:22 Pt 2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin; Seizures; Substance Withdrawal Syndrome

2008
The use of antiepileptic drugs in pediatric brain tumor patients.
    Pediatric neurology, 2009, Volume: 41, Issue:3

    Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Child; Drug Interactions; Follow-Up Studies; Glioma; Humans; Levetiracetam; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Seizures; Supratentorial Neoplasms; Treatment Outcome

2009
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
    Pharmacogenomics, 2010, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; HLA Antigens; HLA-B Antigens; HLA-B15 Antigen; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacogenetics; Phenytoin; Risk Factors; Stevens-Johnson Syndrome; Taiwan; Triazines; Young Adult

2010
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
    Archives of neurology, 2010, Volume: 67, Issue:4

    Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines

2010
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult

2010
Age and comedications influence levetiracetam pharmacokinetics in children.
    Pediatric neurology, 2010, Volume: 43, Issue:4

    Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Triazines; Valproic Acid

2010
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
    Seizure, 2010, Volume: 19, Issue:9

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult

2010
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
    Epilepsy research, 2011, Volume: 96, Issue:3

    Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids

2011
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
    Journal of separation science, 2012, Volume: 35, Issue:3

    Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet

2012
A novel microextraction by packed sorbent-gas chromatography procedure for the simultaneous analysis of antiepileptic drugs in human plasma and urine.
    Journal of separation science, 2012, Volume: 35, Issue:21

    Topics: Alprazolam; Anticonvulsants; Carbamazepine; Epilepsy; Gas Chromatography-Mass Spectrometry; Humans; Oxcarbazepine; Phenytoin; Solid Phase Microextraction

2012
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
    Journal of forensic sciences, 2014, Volume: 59, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Female; Forensic Toxicology; Humans; Hydrocortisone; Liver Cirrhosis; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Young Adult

2014
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid

2014
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Nov-15, Volume: 971

    Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines

2014
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
    Seizure, 2016, Volume: 37

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult

2016
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
    Medicine, 2016, Volume: 95, Issue:35

    Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult

2016
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
    Epilepsy & behavior : E&B, 2018, Volume: 81

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult

2018
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
    The Lancet. Neurology, 2018, Volume: 17, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult

2018
European Academy of Neurology guideline on trigeminal neuralgia.
    European journal of neurology, 2019, Volume: 26, Issue:6

    Topics: Analgesics; Carbamazepine; Decompression, Surgical; Europe; Gabapentin; Humans; Neurology; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia

2019
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
    JAMA neurology, 2019, 07-01, Volume: 76, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsies, Partial; Epilepsy, Generalized; Female; Headache Disorders; Humans; Lamotrigine; Levetiracetam; Mental Disorders; Migraine Disorders; Mood Disorders; Oxcarbazepine; Phenytoin; Retrospective Studies; Risk; Teratogens; Topiramate; Valproic Acid; Young Adult

2019
Silymarin as a flavonoid-type P-glycoprotein inhibitor with impact on the pharmacokinetics of carbamazepine, oxcarbazepine and phenytoin in rats.
    Drug and chemical toxicology, 2021, Volume: 44, Issue:5

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Drug Interactions; Male; Oxcarbazepine; Phenytoin; Rats; Rats, Wistar; Silymarin; Tissue Distribution; Verapamil

2021
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
    Epilepsy research, 2020, Volume: 159

    Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid

2020
Influence of dose and antiepileptic comedication on brivaracetam serum concentrations in patients with epilepsy.
    Epilepsia, 2020, Volume: 61, Issue:5

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Pyrrolidinones; Retrospective Studies; Young Adult

2020
A Rapid LC-MS-MS Method for the Quantitation of Antiepileptic Drugs in Urine.
    Journal of analytical toxicology, 2020, Oct-12, Volume: 44, Issue:7

    Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Drug Monitoring; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Tandem Mass Spectrometry; Topiramate

2020
Heat Shock Proteins Accelerate the Maturation of Brain Endothelial Cell Glucocorticoid Receptor in Focal Human Drug-Resistant Epilepsy.
    Molecular neurobiology, 2020, Volume: 57, Issue:11

    Topics: Adenosine Triphosphatases; Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Blood-Brain Barrier; Brain; Cell Nucleus; Child; Cytochrome P-450 Enzyme System; Drug Resistant Epilepsy; Endothelial Cells; Female; Gene Silencing; Heat-Shock Proteins; Humans; Male; Middle Aged; Oxcarbazepine; Permeability; Phenytoin; Protein Transport; Receptors, Glucocorticoid; Young Adult

2020
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
    Epilepsia, 2021, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity Syndrome; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Republic of Korea; Severity of Illness Index; Stevens-Johnson Syndrome; Topiramate; Young Adult; Zonisamide

2021
HLA alleles and antiseizure medication-induced cutaneous reactions in Brazil: A case-control study.
    HLA, 2023, Volume: 102, Issue:3

    Topics: Alleles; Brazil; Carbamazepine; Case-Control Studies; HLA-A Antigens; HLA-B Antigens; Humans; Oxcarbazepine; Phenobarbital; Phenytoin

2023