phenytoin and oxazepam

phenytoin has been researched along with oxazepam in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199011 (42.31)18.7374
1990's1 (3.85)18.2507
2000's7 (26.92)29.6817
2010's7 (26.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dano, P1
Gardner-Thorpe, C; Parsonage, MJ; Toothill, C1
Eeg-Olofsson, O1
Hegedic, Z; Pürgyi, P1
de Carolis, AS; Longo, VG1
Lou, HO; Sparrevohn, S1
Lou, HO1
Hawksworth, GM; Khir, AS; Petrie, JC; Scott, AK; Steele, WH1
Hillbom, ME; Hjelm-Jäger, M1
Solomon, JG1
Friedman, LS; Mayo-Smith, MF; Saitz, R1
Beerthuizen, G; de Jong, MC; Jonkman, MF; Kardaun, SH; Nieuwenhuis, P; Schuttelaar, ML; Toth, GG; van der Meer, JB1
KuKanich, B; Nauss, JL1

Reviews

1 review(s) available for phenytoin and oxazepam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for phenytoin and oxazepam

ArticleYear
[Oxazepam in the therapy of psychomotor epilepsy].
    Nordisk medicin, 1968, Jul-18, Volume: 80, Issue:29

    Topics: Adolescent; Adult; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Middle Aged; Oxazepam; Phenytoin; Placebos; Time Factors

1968
Oxazepam in the treatment of psychomotor epilepsy.
    Neurology, 1968, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Oxazepam; Phenytoin; Primidone; Seizures

1968

Other Studies

23 other study(ies) available for phenytoin and oxazepam

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
    IARC monographs on the evaluation of the carcinogenic risk of chemicals to man, 1977, Volume: 13

    Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk

1977
Connective tissue disease following anti-epileptic therapy.
    Epilepsia, 1969, Volume: 10, Issue:4

    Topics: Adult; Anticonvulsants; Child; Collagen Diseases; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Latex Fixation Tests; Neutrophils; Oxazepam; Phenytoin; Prednisolone; Primidone

1969
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 35, Issue:1

    Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines

1971
Experiences with Bivotril in treatment of epilepsy--particularly minor motor epilepsy--in mentally retarded children.
    Acta neurologica Scandinavica. Supplementum, 1973, Volume: 53

    Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Child; Child, Preschool; Chlorobenzenes; Drug Interactions; Epilepsy; Fatigue; Female; Humans; Intellectual Disability; Male; Nitro Compounds; Oxazepam; Phenytoin

1973
[Three acute diphenylhydantoin-intoxications (author's transl)].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1974, Volume: 114, Issue:1

    Topics: Adolescent; Adult; Alcoholic Intoxication; Diazepam; Drug Combinations; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Neurologic Manifestations; Oxazepam; Phenytoin; Poisoning; Propylamines; Suicide

1974
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:12

    Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine

1967
Oxazepam pharmacokinetics in patients with epilepsy treated long-term with phenytoin alone or in combination with phenobarbitone.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:4

    Topics: Adult; Bilirubin; Dialysis; Drug Interactions; Epilepsy; Female; Humans; Kinetics; Male; Middle Aged; Oxazepam; Phenobarbital; Phenytoin; Protein Binding

1983
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:1

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazole; Female; Humans; Male; Middle Aged; Oxazepam; Pentobarbital; Phenytoin; Psychoses, Alcoholic; Seizures; Substance Withdrawal Syndrome

1984
Drug interactions on an alcohol unit.
    Virginia medical, 1982, Volume: 109, Issue:4

    Topics: Adult; Alcoholism; Ataxia; Diagnosis, Differential; Drug Interactions; Epilepsy; Humans; Male; Oxazepam; Phenytoin

1982
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
    Journal of general internal medicine, 1995, Volume: 10, Issue:9

    Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine; Data Collection; Diazepam; Drug Administration Schedule; Hypnotics and Sedatives; Inpatients; Lorazepam; Oxazepam; Phenytoin; Substance Withdrawal Syndrome

1995
Successful dexamethasone pulse therapy in a toxic epidermal necrolysis (TEN) patient featuring recurrent TEN to oxazepam.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:8

    Topics: Anticonvulsants; Brain Neoplasms; Dexamethasone; Drug Therapy, Combination; Epidermis; Female; Glucocorticoids; Humans; Hypnotics and Sedatives; Lung Neoplasms; Middle Aged; Oxazepam; Phenytoin; Pulse Therapy, Drug; Stevens-Johnson Syndrome

2001
Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs.
    Journal of veterinary pharmacology and therapeutics, 2012, Volume: 35, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diazepam; Dogs; Female; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Injections, Intravenous; Male; Nordazepam; Oxazepam; Phenytoin; Theophylline

2012