phenytoin has been researched along with nortriptyline in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (61.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 9 (29.03) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bissada, NK; Finkbeiner, AE; Welch, LT | 1 |
| Birkett, DJ; Graham, GG; Pond, SM; Wade, DN | 1 |
| Houghton, GW; Richens, A | 1 |
| Davis, CM; Fenimore, DC; Meyer, CJ | 1 |
| Inaba, T; Kalow, W | 1 |
| Bergman, U; Collste, P | 1 |
| Callaham, M; Pentel, P; Schumaker, H | 1 |
| Passananti, GT; Vessell, ES | 1 |
| Evans, DA | 1 |
| Brittain, RT | 1 |
| Rane, A; Sjöqvist, F | 1 |
| Sjöqvist, F | 2 |
| Kanzler, M; Malitz, S | 1 |
| Borgå, O; Lunde, KM | 1 |
| Azarnoff, DL; Borgå, O; Forshell, GP; Sjöqvist, F | 1 |
| Hrbek, J; Komenda, S; Macáková, J; Siroká, A | 1 |
| Duggan, C; Ferriter, M; Huband, N; Khalifa, N; Lieb, K; Stoffers, J; Völlm, BA | 1 |
| Cheung, NH; Gibbon, S; Khalifa, NR; McCarthy, L; Völlm, BA | 1 |
7 review(s) available for phenytoin and nortriptyline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Uropharmacology: X. Central nervous system stimulants and depressants.
Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract | 1979 |
Genetic factors in hepatic drug oxidation.
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Humans; Liver; Lymphocytes; Male; Mammals; Mixed Function Oxygenases; Models, Biological; Nortriptyline; Oxidation-Reduction; Pharmaceutical Preparations; Phenytoin; Rats | 1976 |
Utility of clinical chemical determinations of drug concentrations in biological fluids.
Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays | 1971 |
Drug metabolism in the human fetus and newborn infant.
Topics: Aminobenzoates; Anti-Bacterial Agents; Bilirubin; Diazepam; Electron Transport; Endoplasmic Reticulum; Ethers, Cyclic; Female; Fetus; Half-Life; Humans; Infant, Newborn; Liver; Maternal-Fetal Exchange; Microsomes, Liver; NADP; Nortriptyline; Pharmaceutical Preparations; Phenytoin; Pregnancy; Sulfobromophthalein; Testosterone | 1972 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; Bromocriptine; Desipramine; Female; Humans; Male; Nortriptyline; Phenytoin; Psychotropic Drugs; Randomized Controlled Trials as Topic | 2010 |
Pharmacological interventions for antisocial personality disorder.
Topics: Adult; Aggression; Alcohol-Related Disorders; Amantadine; Antisocial Personality Disorder; Anxiety; Bromocriptine; Desipramine; Female; Humans; Male; Middle Aged; Nortriptyline; Phenytoin; Placebos; Psychotropic Drugs; Randomized Controlled Trials as Topic | 2020 |
2 trial(s) available for phenytoin and nortriptyline
| Article | Year |
|---|---|
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as Topic; Depression; Dextroamphetamine; Diazepam; Dibenzocycloheptenes; Fatigue; Female; Humans; Male; Middle Aged; Nortriptyline; Perphenazine; Phenytoin; Placebos; Propylamines; Sleep; Xerostomia | 1971 |
On the acute effect of drugs on artificial conditioned verbal associations.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Ascorbic Acid; Association; Chlordiazepoxide; Conditioning, Psychological; Diazepam; Female; Humans; Male; Meprobamate; Nortriptyline; Phenytoin; Placebos; Pyridoxine; Riboflavin; Statistics as Topic; Thiamine; Verbal Behavior | 1970 |
22 other study(ies) available for phenytoin and nortriptyline
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Effects of tricyclic antidepressants on drug metabolism.
Topics: Adult; Amitriptyline; Dicumarol; Half-Life; Humans; Kinetics; Male; Nortriptyline; Pharmaceutical Preparations; Phenytoin; Time Factors; Tolbutamide; Warfarin | 1975 |
Inhibition of phenytoin metabolism by other drugs used in epilepsy.
Topics: Adult; Aged; Chloramphenicol; Chlorpromazine; Depression, Chemical; Drug Interactions; Epilepsy; Half-Life; Humans; Kinetics; Male; Nortriptyline; Phenylbutyrates; Phenytoin; Thiazines; Urea | 1975 |
Determination of drugs in plasma by high-performance thin-layer chromatography.
Topics: Amitriptyline; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Desipramine; Humans; Imipramine; Nortriptyline; Phenobarbital; Phenytoin; Psychotropic Drugs; Spectrophotometry, Ultraviolet | 1978 |
Proceedings: Significance of drug plasma levels based on the plasma level monitoring service of a department of clinical pharmacology.
Topics: Aged; Digoxin; Humans; Middle Aged; Nortriptyline; Phenytoin | 1976 |
Phenytoin prophylaxis of cardiotoxicity in experimental amitriptyline poisoning.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Dogs; Electrocardiography; Heart; Hypotension; Nortriptyline; Phenytoin; Tachycardia | 1988 |
Editorial: Drug metabolism in disease.
Topics: Alanine Transaminase; Anti-Bacterial Agents; Antipyrine; Half-Life; Humans; Kidney; Kidney Diseases; Liver; Liver Diseases; Nortriptyline; Pharmaceutical Preparations; Phenytoin | 1974 |
The hydroxylation of drugs- a pharmacogenetic problem?
Topics: Antipyrine; Dicumarol; Endoplasmic Reticulum; Liver; Mixed Function Oxygenases; Nortriptyline; Pharmacogenetics; Phenylbutazone; Phenytoin | 1970 |
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Nervous System; Chlordiazepoxide; Chlorpheniramine; Chlorpromazine; Diazepam; Drug Antagonism; Haloperidol; Histamine H1 Antagonists; Imipramine; Male; Mice; Norepinephrine; Nortriptyline; Pentobarbital; Phenytoin; Piperazines; Trihexyphenidyl | 1966 |
[Differences between individuals in human pharmacokinetics. Clinical significance].
Topics: Binding Sites; Desipramine; Epilepsy; Female; Humans; Male; Nortriptyline; Pharmacogenetics; Phenytoin | 1972 |
[Inter-individual differences in pharmacokinetics in humans: clinical importance].
Topics: Aged; Biotransformation; Female; Humans; Kinetics; Male; Middle Aged; Nortriptyline; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenytoin; Time Factors | 1973 |
Protein binding nortriptyline and diphenylhydantoin in man.
Topics: Animals; Humans; Norepinephrine; Nortriptyline; Phenytoin; Protein Binding; Rats | 1970 |
Plasma protein binding of tricyclic anti-depressants in man.
Topics: Amitriptyline; Antidepressive Agents; Blood Proteins; Carbon Isotopes; Desipramine; Humans; Imipramine; Nortriptyline; Phenytoin; Protein Binding; Temperature; Tritium | 1969 |