phenytoin has been researched along with nimodipine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 11 (34.38) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
| Anderson, RE; Meyer, FB; Sharbrough, FW; Sundt, TM; Tally, PW; Yaksh, TL | 1 |
| Anderson, RE; Ots, ME; Sundt, TM; Yaksh, TL | 1 |
| Brown, CM; Calder, C; Kenny, BA; Linton, C; Patmore, L; Small, C; Spedding, M | 1 |
| Balakrishnan, S; Bhargava, VK; Pandhi, P | 1 |
| Balakrishnan, S; Pandhi, P | 1 |
| Horga, JF; Javaloy, J; Román, JF; Vidal, MT; Zapater, P | 1 |
| Khosla, P; Pandhi, P | 1 |
| Gidal, BE; Koch, S | 1 |
| Poon, WS; Wong, GK | 1 |
| Auzmendi, J; Bramuglia, GF; Girardi, E; Gonzalez, NN; Höcht, C; Lazarowski, A; Opezzo, JA; Taira, CA | 1 |
| Lanier, WL; Pasternak, JJ | 1 |
| Bharal, N; Jain, S; Mediratta, PK; Sharma, KK | 1 |
| Fogleman, CD | 1 |
| Chen, Y; Liang, M; Liu, Q; Liu, Y; Ma, L; Tan, D; Wang, Y; Zhang, P | 1 |
2 review(s) available for phenytoin and nimodipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Neuroanesthesiology update.
Topics: Anesthesia; Anesthesiology; Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Electroencephalography; Humans; Intracranial Hemorrhages; Ischemic Preconditioning; Monitoring, Physiologic; Nervous System; Neuroprotective Agents; Neurosurgery; Neurosurgical Procedures; Neurotoxicity Syndromes; Nimodipine; Phenytoin; Spine; Subarachnoid Hemorrhage; Treatment Outcome; Vasospasm, Intracranial | 2010 |
30 other study(ies) available for phenytoin and nimodipine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Inhibition of electrically induced seizures by a dihydropyridine calcium channel blocker.
Topics: Animals; Catheterization; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Injections, Intra-Arterial; Ion Channels; Nimodipine; Phenytoin; Rabbits; Seizures; Verapamil | 1986 |
Effect of dihydropyridines and diphenylalkylamines on pentylenetetrazol-induced seizures and cerebral blood flow in cats.
Topics: Animals; Anticonvulsants; Brain; Calcium Channel Blockers; Cats; Cerebrovascular Circulation; Clonazepam; Electroencephalography; Female; Male; Nimodipine; Pentylenetetrazole; Phenytoin; Seizures; Verapamil | 1987 |
Neuroprotective properties of lifarizine compared with those of other agents in a mouse model of focal cerebral ischaemia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraperitoneal; Ischemic Attack, Transient; Isoquinolines; Mice; Neuroprotective Agents; Nimodipine; Phenytoin; Piperazines; Pregnatrienes; Sodium Channels | 1995 |
Effect of nimodipine on the efficacy of commonly used antiepileptic drugs in rats.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Drug Synergism; Electroshock; Female; Male; Nimodipine; Phenytoin; Rats; Seizures; Valproic Acid | 1998 |
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats.
Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, Psychology; Valproic Acid | 1997 |
Anticonvulsant effects of nimodipine and two novel dihydropyridines (PCA 50922 and PCA 50941) against seizures elicited by pentylenetetrazole and electroconvulsive shock in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Clonazepam; Dihydropyridines; Electroshock; Female; Male; Mice; Mice, Inbred Strains; Nimodipine; Pentylenetetrazole; Phenytoin; Seizures; Thiazoles | 1998 |
Anticonvulsant effect of nimodipine alone and in combination with diazepam and phenytoin in a mouse model of status epilepticus.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diazepam; Disease Models, Animal; Drug Therapy, Combination; Female; Male; Mice; Nimodipine; Phenytoin; Psychomotor Performance; Status Epilepticus | 2000 |
Phenytoin and cognitive decline.
Topics: Anticonvulsants; Area Under Curve; Calcium Channel Blockers; Cognition Disorders; Cytochrome P-450 Enzyme System; Humans; Nimodipine; Phenytoin; Seizures; Time Factors; Treatment Outcome | 2005 |
Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage.
Topics: Cognition Disorders; Drug Interactions; Humans; Intracranial Aneurysm; Nimodipine; Phenytoin; Seizures; Subarachnoid Hemorrhage; Valproic Acid | 2005 |
Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Convulsants; Disease Models, Animal; Drug Resistance; Epilepsy; Extracellular Fluid; Hippocampus; Male; Microdialysis; Nimodipine; Phenytoin; Rats; Rats, Wistar | 2007 |
Trimetazidine exerts protection against increasing current electroshock seizure test in mice.
Topics: Animals; Anticonvulsants; Calcium Channels; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nimodipine; Phenytoin; Seizures; Trimetazidine; Vasodilator Agents | 2010 |
Magnesium sulfate and other anticonvulsants for women with preeclampsia.
Topics: Anticonvulsants; Clinical Trials as Topic; Evidence-Based Medicine; Female; Humans; Magnesium Sulfate; Nimodipine; Phenytoin; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
The Prevention and Reversal of a Phenytoin-Resistant Model by N-acetylcysteine Therapy Involves the Nrf2/P-Glycoprotein Pathway at the Blood-Brain Barrier.
Topics: Acetylcysteine; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Drug Resistant Epilepsy; Mice; NF-E2-Related Factor 2; Nimodipine; Phenytoin | 2022 |