phenytoin and nifedipine

phenytoin has been researched along with nifedipine in 105 studies

Research

Studies (105)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (16.19)	18.7374
1990's	37 (35.24)	18.2507
2000's	24 (22.86)	29.6817
2010's	26 (24.76)	24.3611
2020's	1 (0.95)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Antkiewicz-Michaluk, L; Marona, H; Pekala, E; Szneler, E; Walczak, M	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Sen, S; Sinha, N	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Bharathi, K; Prasad, KV; Prasanthi, G	2
Brouillette, WJ; Brown, GB; Zha, C	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Hashiguchi, M; Hashiguchi, T; Kanazawa, M; Miyazaki, T; Sakai, S; Tosaka, T	1
Bernimoulin, JP; Hinz, N; Romanos, GE; Schröter-Kermani, C	1
Danielson, M; Danielsson, BR; Reiland, S; Rundqvist, E	1
Beaver, WT; Bottomley, WK; Brown, RS	1
Kano, M; Nakabayashi, Y; Satoh, R	1
Bosker, H; Jordan, RD; Koole, R; Sindet-Pedersen, S	1
Bahls, FH; Ozuna, J; Ritchie, DE	1
Breimer, DD; Hoevers, JW; Schellens, JH; Soons, PA; van der Wart, JH	1
Røed, A	1
Hahn, G; Menard, MR	1
Kano, M; Kudo, Y; Suzuki, N; Takagi, H; Tanakadate, A; Yoshioka, T	1
Oikarinen, AI; Oikarinen, KS; Salo, T	1
Carpenter, CL; Greenberg, DA; Messing, RO	1
Calixto, JB	1
Gerthoffer, WT; Shafer, PG; Taylor, S	1
Lundergan, WP	1
Dretchen, KL; Henderson, TR; Raines, A	1
Ferrés, E; López Colomés, JL; Moreno, A; Villena, J	1
Bruno, P; Bylund, DB; Harris, RA; Jones, SB	1
Bencini, L; Marini, D; Piferi, M; Sala, F; Silvestri, E; Veraldi, S	1
Yusof, WZ	1
Butler, RT; Kaldahl, WB; Kalkwarf, KL	1
Ciancio, SG	1
Howell, LP; Lucas, RM; Wall, BA	1
Carpenter, CL; Cooper, EC; Greenberg, DA	1
Connolly, SM	1
Ahmad, S	1
Lazarus, LH; Spracklen, FH	1
Levine, RA; Rees, TD	1
Ben-Chitrit, S; Bernheim, J; Korzets, Z	1
Bliesath, H; Hartmann, M; Huber, R; Radtke, HW; Steinijans, VW; Wurst, W; Zech, K	1
Ullal, GR	1
Akimoto, Y; Fujii, A; Matsumoto, H; Nakao, S; Teshigawara, H	1
Ikeda, M; Kamata, R; Kasamo, K; Kojima, T; Nogami, Y; Okuhata, Y; Satoh, R; Takahashi, S	1
Oda, Y; Okada, Y; Shikata, H; Shimojima, T; Utsumi, N	1
Bernimoulin, JP; Romanos, GE; Strub, JR	1
Pleuvry, BJ; Rodger, C	1
Knowles, GC; McCulloch, CA	1
Ishida, H; Morisaki, I; Nagata, T; Nishikawa, S; Oka, T	1
Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J	1
Iwakura, M; Mori, S; Saito, K; Sakamoto, S	1
Satishchandra, P; Shankar, SK; Ullal, GR	1
Inoue, K; Mimura, M; Nakamura, S; Oda, H; Ohmori, S; Shimada, T; Yamazaki, H	1
Slezák, R	1
Abu-el-Dahab, O; el-Sherbiny, MM; Fathy, LM; Shoieb, MA	1
Botha, PJ	1
Desai, P; Silver, JG	1
Hall, EE	1
Gopalakrishna, HN; Raju, SS; Venkatadri, N	1
Blaisdell, J; Dalton, JT; Goldstein, JA; Kidd, RS; Meyer, MC; Straughn, AB	1
Dokoumetzidis, A; Macheras, P; Valsami, G	1
Mori, S; Saito, K; Sakamoto, S; Tanda, N	2
Dongari-Bagtzoglou, AI; Morton, RS	1
Kokue, E; Saitoh, T; Shimoda, M	1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA	1
Firatli, E; Hong, HH; Kantarci, A; Sheff, MC; Trackman, PC; Uygur, C; Uzel, MI	1
Lowenthal, A; Lowenthal, MN	1
Akimoto, Y; Fujii, A; Matsumoto, H; Noji, I	1
Kantarci, A; Trackman, PC	1
Inoue, T; Kizawa, Y; Murakami, H; Ohuchi, N; Sano, M; Tachikawa, T; Tono, K	1
Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T	1
de Morais, SM; Fahmi, OA; Liras, JL; Maurer, TS; Mills, JB; Ripp, SL; Trevena, KA	1
Buduneli, E; Buduneli, N; Cinar, S; Kinane, DF; Lappin, D	1
Augustin, P; Firatli, E; Graves, DT; Hasturk, H; Kantarci, A; Sheff, MC; Trackman, PC	1
Castro, AL; Crivelini, MM; Garcia, JF; Kanno, CM; Oliveira, JA	1
Bhattacharyya, I; Cohen, D	1
Chou, D; Duley, L; Henderson-Smart, DJ	1
Kantarci, A; Kim, YS; Nseir, Z; Sume, SS; Trackman, PC	1
Ashrafi, SS; Nakib, N	1
De Gusmao, C; Echeverria, Y; Forteza, A; Gutierrez, J; Haussen, DC; Wiley, E	1
Nilsson, MF; Ritchie, H; Webster, WS	1
Bian, Z; Fang, YJ; Meng, LY; Tay, FR; Zhao, XH	1
Ervolino, E; Kanno, CM; Oliveira, JA; Soubhia, AMP	1
Song, J; Wang, X; Wu, J; Zhang, R; Zhu, J	1

Reviews

15 review(s) available for phenytoin and nifedipine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
On the mechanism of drug-induced gingival hyperplasia. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1991, Volume: 20, Issue:5 Topics: Dental Plaque; Diltiazem; Epidermal Growth Factor; Fibroblasts; Folic Acid; Gingival Hyperplasia; Glycosaminoglycans; Humans; Immunoglobulin Isotypes; Microbial Collagenase; Nifedipine; Phenytoin	1991
Scleroderma: therapeutic options. Cutis, 1984, Volume: 34, Issue:3 Topics: Alprostadil; Captopril; Colchicine; Griseofulvin; Humans; Immunosuppressive Agents; Nifedipine; Penicillamine; Phenytoin; Physical Therapy Modalities; Plasmapheresis; Prostaglandins E; Scleroderma, Systemic; Vasodilator Agents	1984
Systematic drugs as a risk factor for periodontal disease initiation and progression. Compendium (Newtown, Pa.), 1995, Volume: 16, Issue:1 Topics: Calcium Channel Blockers; Cyclosporine; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Gonadal Steroid Hormones; Humans; Male; Nifedipine; Phenytoin	1995
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model. Journal of periodontology, 1996, Volume: 67, Issue:5 Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Gingival Hyperplasia; Gingivitis; Humans; Immunosuppressive Agents; Male; Nifedipine; Phenytoin; Rats; Rats, Inbred F344; Sex Factors; Specific Pathogen-Free Organisms	1996
Gingival enlargement induced by drugs. Drug safety, 1996, Volume: 15, Issue:3 Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin	1996
Drug-induced gingival overgrowth after phenytoin and nifedipine therapy. A case report. The Journal of the Western Society of Periodontology/Periodontal abstracts, 1997, Volume: 45, Issue:4 Topics: Anticonvulsants; Calcium Channel Blockers; Drug Therapy, Combination; Female; Gingival Overgrowth; Humans; Middle Aged; Nifedipine; Periodontitis; Phenytoin; Tooth Extraction	1997
Drug-induced gingival hyperplasia and its management--a literature review. The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1997, Volume: 52, Issue:11 Topics: Anticonvulsants; Calcium Channel Blockers; Clinical Protocols; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin	1997
Drug-induced gingival enlargements. Journal (Canadian Dental Association), 1998, Volume: 64, Issue:4 Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin; Verapamil	1998
Prevention and treatment considerations in patients with drug-induced gingival enlargement. Current opinion in periodontology, 1997, Volume: 4 Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Prophylaxis; Gingival Overgrowth; Gingivectomy; Humans; Immunosuppressive Agents; Nifedipine; Oral Hygiene; Phenytoin	1997
Connective tissue metabolism and gingival overgrowth. Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists, 2004, Jun-04, Volume: 15, Issue:3 Topics: Animals; Anticonvulsants; Antihypertensive Agents; Connective Tissue; Connective Tissue Growth Factor; Cyclosporine; Extracellular Matrix; Fibroblasts; Gingival Overgrowth; Growth Substances; Humans; Immediate-Early Proteins; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Nifedipine; Phagocytosis; Phenytoin	2004
Magnesium sulphate versus phenytoin for eclampsia. The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10 Topics: Anticonvulsants; Clonazepam; Diazepam; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic	2010
Drug-induced gingival overgrowth. Disease-a-month : DM, 2011, Volume: 57, Issue:4 Topics: Adult; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin; Prevalence; Risk Factors	2011
Bibliometric analysis of research trends and characteristics of drug-induced gingival overgrowth. Frontiers in public health, 2022, Volume: 10 Topics: Amlodipine; Anticonvulsants; Bibliometrics; Calcium Channel Blockers; Cyclosporine; Gingival Overgrowth; Humans; Immunosuppressive Agents; Nifedipine; Phenytoin	2022

Trials

2 trial(s) available for phenytoin and nifedipine

Article	Year
Lack of pharmacokinetic interaction between nifedipine, sparteine and phenytoin in man. British journal of clinical pharmacology, 1991, Volume: 31, Issue:2 Topics: Administration, Oral; Adult; Drug Interactions; Female; Humans; Male; Nifedipine; Oxidation-Reduction; Phenytoin; Sparteine	1991
Lack of pantoprazole drug interactions in man. International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin	1994

Article

Year

Lack of pharmacokinetic interaction between nifedipine, sparteine and phenytoin in man.

British journal of clinical pharmacology, 1991, Volume: 31, Issue:2

Topics: Administration, Oral; Adult; Drug Interactions; Female; Humans; Male; Nifedipine; Oxidation-Reduction; Phenytoin; Sparteine

1991

Lack of pantoprazole drug interactions in man.

International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:8

Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Absorption; Antipyrine; Benzimidazoles; Contraceptives, Oral, Hormonal; Cross-Over Studies; Cytochrome P-450 Enzyme System; Diazepam; Digoxin; Drug Interactions; Female; Humans; Liver; Longitudinal Studies; Male; Nifedipine; Omeprazole; Pantoprazole; Phenytoin; Proton Pump Inhibitors; Sulfoxides; Theophylline; Tissue Distribution; Warfarin

1994

Other Studies

89 other study(ies) available for phenytoin and nifedipine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents. Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18 Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Anticonvulsant activity of some xanthone derivatives. Bioorganic & medicinal chemistry, 2008, Aug-01, Volume: 16, Issue:15 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Xanthones	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction. European journal of medicinal chemistry, 2013, Volume: 66 Topics: Absorption; Analgesics; Animals; Anticonvulsants; Antioxidants; Chemistry Techniques, Synthetic; Drug Design; Male; Mice; Pyridines; Rats	2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels	2014
Synthesis, anticonvulsant activity and molecular properties prediction of dialkyl 1-(di(ethoxycarbonyl)methyl)-2,6-dimethyl-4-substituted-1,4-dihydropyridine-3,5-dicarboxylates. European journal of medicinal chemistry, 2014, Feb-12, Volume: 73 Topics: Administration, Oral; Animals; Anticonvulsants; Dihydropyridines; Drug Design; Male; Mice; Molecular Structure; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Toxicity Tests, Acute	2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Phenytoin partially antagonized L-type Ca2+ current in glucagon-secreting tumor cells (ITC-1). Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1 Topics: Animals; Barium; Calcium; Calcium Channels; Cricetinae; Electrophysiology; Glucagon; Lanthanum; Membrane Potentials; Mesocricetus; Nifedipine; Phenytoin; Tumor Cells, Cultured	1992
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1992, Volume: 21, Issue:6 Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; Epithelium; Female; Fibronectins; Fluorescent Antibody Technique; Gingiva; Gingival Hemorrhage; Gingival Hyperplasia; Gingival Pocket; Gingivitis; Humans; Male; Middle Aged; Nifedipine; Phenytoin	1992
Identical phalangeal defects induced by phenytoin and nifedipine suggest fetal hypoxia and vascular disruption behind phenytoin teratogenicity. Teratology, 1992, Volume: 45, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Blood Vessels; Female; Fetal Hypoxia; Gestational Age; Heart Rate; Humans; Nifedipine; Phenytoin; Pregnancy; Rabbits; Toes	1992
Pharmacological properties of two types of calcium channel in embryonic chick skeletal muscle cells in culture. Neuroscience letters, 1991, Jan-28, Volume: 122, Issue:2 Topics: Action Potentials; Animals; Calcium Channels; Cations; Cells, Cultured; Chick Embryo; Gallopamil; Kinetics; Mollusk Venoms; Muscles; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Phenytoin	1991
The transmandibular implant: a 13-year survey of its use. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival Hyperplasia; Humans; Male; Mandibular Injuries; Middle Aged; Nifedipine; Pain; Phenytoin; Pipemidic Acid; Prognosis; Prosthesis Failure; Skin Transplantation; Surgical Wound Infection; Wounds, Nonpenetrating	1991
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin. Neurology, 1991, Volume: 41, Issue:5 Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Retrospective Studies; Seizures; Verapamil	1991
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation. General pharmacology, 1991, Volume: 22, Issue:2 Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Membranes; Muscle Contraction; Nifedipine; Phenytoin; Potassium; Quinine; Rats; Rats, Inbred Strains; Respiratory Muscles	1991
Acute and chronic hypothermia in a man with spinal cord injury: environmental and pharmacologic causes. Archives of physical medicine and rehabilitation, 1991, Volume: 72, Issue:6 Topics: Adult; Autonomic Nervous System; Body Temperature Regulation; Humans; Hypothermia; Male; Nifedipine; Phenytoin; Spinal Cord Injuries	1991
Participation of transient-type Ca2+ channels in the sustained increase of Ca2+ level in GH3 cells. Journal of cellular physiology, 1990, Volume: 144, Issue:1 Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Electric Conductivity; In Vitro Techniques; Membrane Potentials; Nickel; Nifedipine; omega-Conotoxin GVIA; Peptides, Cyclic; Phenytoin; Pituitary Gland; Rats; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured; Verapamil	1990
Effect of phenytoin and nifedipine on collagen gene expression in human gingival fibroblasts. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1990, Volume: 19, Issue:9 Topics: Adolescent; Blotting, Northern; Cell Division; Cells, Cultured; Child; Collagen; Fibroblasts; Gene Expression; Gingiva; Humans; Matrix Metalloproteinase 9; Microbial Collagenase; Nifedipine; Nucleic Acid Hybridization; Phenytoin; Protein Biosynthesis; RNA, Messenger	1990
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil	1985
Effect of diphenylhydantoin on drug and calcium induced contractions of isolated rat uterus: a comparative study with nifedipine. General pharmacology, 1987, Volume: 18, Issue:3 Topics: Acetylcholine; Animals; Calcium; Female; In Vitro Techniques; Ion Channels; Nifedipine; Oxytocin; Phenytoin; Rats; Time Factors; Uterine Contraction	1987
Selectivity of phenytoin and dihydropyridine calcium channel blockers for relaxation of the basilar artery. Journal of cardiovascular pharmacology, 1987, Volume: 10, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Dinoprost; Dogs; Dose-Response Relationship, Drug; Nifedipine; Phenytoin; Potassium; Prostaglandins F; Serotonin; Vasoconstriction; Vasodilation	1987
Drug-induced gingival enlargements. Journal of the California Dental Association, 1989, Volume: 17, Issue:6 Topics: Adult; Cyclosporins; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin	1989
Effects of calcium channel blocking agents on neostigmine-induced fasciculations. European journal of pharmacology, 1989, Nov-28, Volume: 173, Issue:1 Topics: Animals; Calcium Channel Blockers; Electric Stimulation; Facial Muscles; Fasciculation; Male; Neostigmine; Nerve Endings; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Verapamil	1989
[Gingival hyperplasia associated with nifedipine]. Revista clinica espanola, 1989, Volume: 184, Issue:6 Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin	1989
Effects of dihydropyridine derivatives and anticonvulsant drugs on [3H]nitrendipine binding and calcium and sodium fluxes in brain. Biochemical pharmacology, 1985, Jun-15, Volume: 34, Issue:12 Topics: Animals; Anticonvulsants; Barbiturates; Brain; Calcium; Ethanol; In Vitro Techniques; Kinetics; Male; Nifedipine; Nitrendipine; Phenytoin; Rats; Rats, Inbred Strains; Sodium; Tritium	1985
[Gingival hyperplasia due to diphenylhydantoin, cyclosporin A and nifedipine. A histopathological comparison]. Minerva stomatologica, 1988, Volume: 37, Issue:3 Topics: Biopsy; Connective Tissue; Cyclosporins; Gingiva; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin	1988
Gingival hyperplasia: an intra-oral side effect of phenytoin, nifedipine and cyclosporine therapies. Singapore medical journal, 1988, Volume: 29, Issue:5 Topics: Adult; Cyclosporins; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin	1988
Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine. Journal of the American Dental Association (1939), 1987, Volume: 114, Issue:1 Topics: Adult; Child; Cyclosporins; Female; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin	1987
Drugs in dentistry. Medications for gingival hyperplasia. Dental management, 1987, Volume: 27, Issue:11 Topics: Cyclosporins; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin	1987
Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. Journal of periodontology, 1985, Volume: 56, Issue:4 Topics: Acid Phosphatase; Adult; Aged; Alcian Blue; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin	1985
Phenytoin interacts with calcium channels in brain membranes. Annals of neurology, 1984, Volume: 16, Issue:5 Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid	1984
Nifedipine--phenytoin interaction. Journal of the American College of Cardiology, 1984, Volume: 3, Issue:6 Topics: Drug Interactions; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Nifedipine; Phenytoin	1984
Nifedipine for digitalis-induced arrhythmias. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jun-21, Volume: 57, Issue:25 Topics: Animals; Arrhythmias, Cardiac; Dogs; Nifedipine; Phenytoin; Pyridines; Strophanthins; Verapamil	1980
Bradycardia as a presenting feature of late postpartum eclampsia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:8 Topics: Adult; Bradycardia; Drug Therapy, Combination; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenobarbital; Phenytoin; Pregnancy; Puerperal Disorders; Time Factors	1994
Dihydropyridine group of calcium channel antagonist in epilepsy. Indian journal of physiology and pharmacology, 1994, Volume: 38, Issue:1 Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Electrodes, Implanted; Electroencephalography; Electroshock; Epilepsy; Hippocampus; Kindling, Neurologic; Male; Nifedipine; Phenytoin; Rats; Rats, Wistar	1994
Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders. Archives of oral biology, 1994, Volume: 39, Issue:2 Topics: Adult; Aged; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; Collagen; DNA; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin	1994
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report. European archives of psychiatry and clinical neuroscience, 1993, Volume: 243, Issue:2 Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted	1993
Increased expression of type VI collagen genes in drug-induced gingival enlargement. FEBS letters, 1993, Nov-08, Volume: 334, Issue:1 Topics: Animals; Blotting, Northern; Cells, Cultured; Collagen; Fibroblasts; Gene Expression; Gingival Diseases; Humans; Immunohistochemistry; Nifedipine; Phenytoin; Rabbits; Rats; RNA, Messenger	1993
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva. Journal of periodontology, 1993, Volume: 64, Issue:2 Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescent Antibody Technique; Gingiva; Gingival Hyperplasia; Gingivitis; Glycoproteins; Humans; Immunohistochemistry; Male; Microscopy, Fluorescence; Middle Aged; Nifedipine; Phenytoin	1993
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice. Neuropharmacology, 1993, Volume: 32, Issue:3 Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures	1993
Deficiencies in collagen phagocytosis by human fibroblasts in vitro: a mechanism for fibrosis? Journal of cellular physiology, 1993, Volume: 155, Issue:3 Topics: Adolescent; Adult; Cell Division; Cell Line; Collagen; Fibroblasts; Fibrosis; Flow Cytometry; Fluorescent Dyes; Gingiva; Humans; Microscopy, Electron, Scanning; Microspheres; Nifedipine; Phagocytosis; Phenytoin	1993
Immunohistochemical localization of transforming growth factor beta, basic fibroblast growth factor and heparan sulphate glycosaminoglycan in gingival hyperplasia induced by nifedipine and phenytoin. Journal of periodontal research, 1996, Volume: 31, Issue:8 Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Cell Count; Coloring Agents; Female; Fibroblast Growth Factor 2; Gingiva; Gingival Hyperplasia; Heparitin Sulfate; Humans; Immunohistochemistry; Male; Nifedipine; Phenytoin; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta	1996
Effect of antiepileptic drugs and calcium channel blocker on hyperthermic seizures in rats: animal model for hot water epilepsy. Indian journal of physiology and pharmacology, 1996, Volume: 40, Issue:4 Topics: Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Disease Models, Animal; Electroencephalography; Epilepsy; Hippocampus; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Nifedipine; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures	1996
Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. Archives of toxicology, 1997, Volume: 71, Issue:6 Topics: Adrenergic beta-Antagonists; Aniline Compounds; Animals; Antineoplastic Agents; Benzphetamine; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Dogs; Erythromycin; Ethanolamines; Ethylmorphine; Guinea Pigs; Humans; Macaca fascicularis; Mephenytoin; Microsomes, Liver; Nifedipine; Oxazines; Oxidation-Reduction; Phenacetin; Phenytoin; Rats; Species Specificity	1997
A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva. Egyptian dental journal, 1993, Volume: 39, Issue:4 Topics: Anticonvulsants; Biopsy; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin; Time Factors	1993
Effect of propranolol and nifedipine on maximal electroshock-induced seizures in mice: individually and in combination. Pharmacological research, 1998, Volume: 38, Issue:6 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Nifedipine; Phenytoin; Propranolol; Rats; Rats, Wistar; Seizures	1998
Pharmacokinetics of chlorpheniramine, phenytoin, glipizide and nifedipine in an individual homozygous for the CYP2C93 allele. Pharmacogenetics, 1999, Volume: 9, Issue:1* Topics: Adult; Alleles; Aryl Hydrocarbon Hydroxylases; Chlorpheniramine; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Genotype; Glipizide; Homozygote; Humans; Male; Nifedipine; Phenotype; Phenytoin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases	1999
Modeling of supersaturated dissolution data. International journal of pharmaceutics, 1999, Apr-30, Volume: 181, Issue:2 Topics: Chemistry, Pharmaceutical; Models, Chemical; Nifedipine; Phenytoin; Solutions	1999
Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. Journal of periodontology, 1999, Volume: 70, Issue:6 Topics: Adolescent; Adult; Anticonvulsants; Biomarkers, Tumor; Calcium Channel Blockers; Carcinoma, Squamous Cell; Cells, Cultured; Culture Techniques; DNA Damage; Female; Fibroblasts; Gingival Hyperplasia; Gingival Neoplasms; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Male; Middle Aged; Nifedipine; Phenytoin; Tumor Suppressor Protein p53	1999
Regulation of gingival fibroblast interleukin-6 secretion by cyclosporine A. Journal of periodontology, 1999, Volume: 70, Issue:12 Topics: Anticonvulsants; Bacteria; Calcium Channel Blockers; Cell Division; Cells, Cultured; Cyclosporine; Down-Regulation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gingiva; Gingival Overgrowth; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-6; Nifedipine; Phenytoin; Tumor Necrosis Factor-alpha; Up-Regulation	1999
Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin. Journal of periodontology, 2000, Volume: 71, Issue:1 Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Epithelial Cells; Epithelium; Female; Gene Expression Regulation; Gingiva; Gingival Hyperplasia; Homeostasis; Humans; Immunoenzyme Techniques; Immunohistochemistry; Male; Middle Aged; Morphogenesis; Nifedipine; Phenytoin; Proto-Oncogene Mas; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc	2000
The impact of acute phase response on the plasma clearance of antipyrine, theophylline, phenytoin and nifedipine in rabbits. Journal of veterinary pharmacology and therapeutics, 2000, Volume: 23, Issue:3 Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antipyrine; Area Under Curve; Chromatography, High Pressure Liquid; Escherichia coli; Female; Half-Life; Injections, Intramuscular; Interleukin-6; Lipopolysaccharides; Metabolic Clearance Rate; Nifedipine; Phenytoin; Protein Binding; Rabbits; Theophylline; Vasodilator Agents	2000
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. The Journal of endocrinology, 2000, Volume: 167, Issue:3 Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil	2000
Connective tissue growth factor in drug-induced gingival overgrowth. Journal of periodontology, 2001, Volume: 72, Issue:7 Topics: Adult; Antibodies; Anticonvulsants; Calcium Channel Blockers; Carrier Proteins; Coloring Agents; Connective Tissue; Connective Tissue Growth Factor; Cyclosporine; Endothelium, Vascular; Epithelium; Female; Fibroblasts; Fibrosis; Gingival Overgrowth; Growth Substances; Humans; Image Processing, Computer-Assisted; Immediate-Early Proteins; Immunoenzyme Techniques; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Male; Middle Aged; Mitogens; Neovascularization, Pathologic; Nifedipine; Phenytoin; Platelet Endothelial Cell Adhesion Molecule-1; Statistics, Nonparametric; Transforming Growth Factor beta; Transforming Growth Factor beta1	2001
Gingival hypertrophy due to drugs. The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:9 Topics: Adolescent; Anticonvulsants; Female; Gingival Hypertrophy; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Tocolytic Agents	2001
Comparative study of calcium-channel blockers on cell proliferation, DNA and collagen syntheses, and EGF receptors of cultured gingival fibroblasts derived from human nifedipine, nicardipine and nisoldipine responders. Journal of oral science, 2001, Volume: 43, Issue:4 Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Calcium Channel Blockers; Cell Culture Techniques; Cell Division; Collagen; Diltiazem; DNA; ErbB Receptors; Female; Fibroblasts; Flow Cytometry; Gingiva; Gingival Overgrowth; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Phenytoin; Radiopharmaceuticals; Statistics as Topic; Tritium; Verapamil	2001
Proliferative response to phenytoin and nifedipine in gingival fibroblasts cultured from humans with gingival fibromatosis. Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4 Topics: Anticonvulsants; Antihypertensive Agents; Calcium Channel Blockers; Cells, Cultured; Endothelin-1; Fibroblasts; Fibromatosis, Gingival; Humans; Nifedipine; Peptides, Cyclic; Phenytoin	2004
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. The AAPS journal, 2005, Mar-04, Volume: 7, Issue:1 Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin	2005
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:10 Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones	2006
Immunohistochemical evaluation of Ki-67 expression and apoptosis in cyclosporin A-induced gingival overgrowth. Journal of periodontology, 2007, Volume: 78, Issue:2 Topics: Adult; Analysis of Variance; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Cell Proliferation; Cyclosporine; Female; Gingival Overgrowth; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Ki-67 Antigen; Kidney Transplantation; Male; Mitosis; Nifedipine; Phenytoin; Statistics, Nonparametric	2007
Apoptosis in gingival overgrowth tissues. Journal of dental research, 2007, Volume: 86, Issue:9 Topics: Anticonvulsants; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Caspase 3; Cell Proliferation; Cyclosporine; Fibroblasts; Fibromatosis, Gingival; Forkhead Box Protein O1; Forkhead Transcription Factors; Gingival Overgrowth; Gingivitis; Humans; Immunosuppressive Agents; In Situ Nick-End Labeling; Nifedipine; Phenytoin; Proliferating Cell Nuclear Antigen	2007
Effects of cyclosporin, phenytoin, and nifedipine on the synthesis and degradation of gingival collagen in tufted capuchin monkeys (Cebus apella): histochemical and MMP-1 and -2 and collagen I gene expression analyses. Journal of periodontology, 2008, Volume: 79, Issue:1 Topics: Animals; Anticonvulsants; Azo Compounds; Biopsy; Calcium Channel Blockers; Cebus; Collagen; Collagen Type I; Collagen Type IV; Coloring Agents; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gingiva; Gingival Overgrowth; Gingivitis; Histocytochemistry; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Nifedipine; Phenytoin; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction	2008
Case of the month: drug-induced hyperplasia. Today's FDA : official monthly journal of the Florida Dental Association, 2008, Volume: 20, Issue:3 Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin	2008
Loss of basement membrane integrity in human gingival overgrowth. Journal of dental research, 2011, Volume: 90, Issue:7 Topics: Adult; Analysis of Variance; Basement Membrane; Case-Control Studies; Cell Adhesion Molecules; Collagen Type IV; Cyclosporine; Epithelial-Mesenchymal Transition; Female; Gene Expression; Gingival Overgrowth; Humans; Kalinin; Male; Nifedipine; Phenytoin; Statistics, Nonparametric; Young Adult	2011
Cerebral vasomotor reactivity monitoring in posterior reversible encephalopathy syndrome. BMJ case reports, 2010, Oct-12, Volume: 2010 Topics: Adrenergic beta-Antagonists; Adult; Anticonvulsants; Calcium Channel Blockers; Diagnosis, Differential; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenytoin; Posterior Leukoencephalopathy Syndrome; Ultrasonography, Doppler, Transcranial	2010
Oral pathology quiz # 75. Case number 4. Systemic medication. Journal of the New Jersey Dental Association, 2012,Spring, Volume: 83, Issue:2 Topics: Anticonvulsants; Cyclosporine; Diagnosis, Differential; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Phenytoin; Vasodilator Agents	2012
The effect on rat embryonic heart rate of Na+, K+, and Ca2+ channel blockers, and the human teratogen phenytoin, changes with gestational age. Birth defects research. Part B, Developmental and reproductive toxicology, 2013, Volume: 98, Issue:5 Topics: Animals; Calcium Channel Blockers; Female; Gestational Age; Heart Rate, Fetal; Lidocaine; Nifedipine; Phenethylamines; Phenytoin; Potassium Channel Blockers; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sulfonamides	2013
Topical application of phenytoin or nifedipine-loaded PLGA microspheres promotes periodontal regeneration in vivo. Archives of oral biology, 2019, Volume: 97 Topics: Administration, Topical; Alveolar Bone Loss; Animals; Biomarkers; Cyclosporine; Drug Carriers; Gingival Recession; Immunohistochemistry; Male; Microspheres; Nifedipine; Phenytoin; Polyesters; Random Allocation; Rats; Rats, Sprague-Dawley; Single-Blind Method; X-Ray Microtomography	2019
Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys. Journal of applied oral science : revista FOB, 2018, Nov-08, Volume: 27 Topics: Actins; Animals; Apoptosis; Biopsy; Cell Proliferation; Cell Transdifferentiation; Cyclosporine; Genes, bcl-2; Gingiva; Gingival Overgrowth; Haplorhini; Immunohistochemistry; Ki-67 Antigen; Longitudinal Studies; Male; Myofibroblasts; Nifedipine; Phenytoin; Random Allocation	2018