phenytoin and niacin

phenytoin has been researched along with niacin in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's2 (14.29)18.2507
2000's0 (0.00)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Glueck, CJ1
Balazs, T; Ehrreich, SJ; el-Hage, AN; Johnson, GL1
Iwaki, M; Muraoka, O; Ogiso, T; Tanabe, G; Tanino, T1
FAGER, CA1
Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J1
Grimm, U; Schlenzka, K1

Reviews

1 review(s) available for phenytoin and niacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for phenytoin and niacin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Nonpharmacologic and pharmacologic alteration of high-density lipoprotein cholesterol: therapeutic approaches to prevention of atherosclerosis.
    American heart journal, 1985, Volume: 110, Issue:5

    Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Arteriosclerosis; Body Weight; Cholesterol, HDL; Estrogens; Ethanol; Gemfibrozil; Niacin; Pentanoic Acids; Phenytoin; Physical Fitness; Pyrimidines; Risk; Smoking; Terbutaline; Vasodilator Agents

1985
Effects of antiarrhythmic agents on isoproterenol-induced ventricular fibrillation in heavy rats: a possible model of sudden cardiac death.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 51, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Body Weight; Bretylium Tosylate; Death, Sudden; Disease Models, Animal; Electrocardiography; Isoproterenol; Male; Niacin; Phenytoin; Procainamide; Propranolol; Quaternary Ammonium Compounds; Quinidine; Rats; Ventricular Fibrillation; Verapamil

1986
Physicochemical and hydrolytic characteristics of phenytoin derivatives.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:10

    Topics: Animals; Blood Proteins; Brain; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Intestine, Small; Linear Models; Liver; Niacin; Phenytoin; Protein Binding; Rats; Serum Albumin, Bovine

1994
TRIGEMINAL NEURALGIA.
    Geriatrics, 1965, Volume: 20

    Topics: Atropa belladonna; Diagnosis; Drug Therapy; Geriatrics; Neurosurgery; Neurosurgical Procedures; Niacin; Nicotinic Acids; Parasympatholytics; Phenobarbital; Phenytoin; Thiamine; Trichloroethylene; Trigeminal Neuralgia

1965
[Pellagra in anticonvulsive therapy].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1990, Volume: 138, Issue:12

    Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellectual Disability; Pellagra; Phenytoin; Photosensitivity Disorders; Valproic Acid; Vitamins

1990
[Studies on tryptophan metabolism in pellagra with special reference to drug-induced pellagra following INH and anticonvulsants].
    Dermatologische Monatschrift, 1974, Volume: 160, Issue:10

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Female; Humans; Isoniazid; Male; Middle Aged; Nutrition Disorders; Pellagra; Phenytoin; Tryptophan

1974