phenytoin has been researched along with nadp in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (84.21) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butler, TC; Dudley, KH; Johnson, D; Mitchell, GN | 1 |
| Branch, RA; Guengerich, FP; Hall, SD; Wilkinson, GR | 1 |
| Billings, RE; Milton, SG | 1 |
| Kitteringham, NR; Lambert, C; Maggs, JL; Park, BK; Riley, RJ | 1 |
| Bronaugh, RL; Erwin, VG | 1 |
| Deitrich, RA; Erwin, VG | 1 |
| Bernstein, JD; Johnson, SL | 1 |
| MacGee, J; Sholiton, LJ; Werk, EE | 1 |
| Hagihara, B; Ichikawa, Y; Yamano, T | 1 |
| Bruggeman, LL; Kupfer, D; Munsell, T | 1 |
| Becker, BA; Eling, TE; Fouts, JR; Harbison, RD | 1 |
| Kutt, H; Verebely, K | 1 |
| Rane, A; Sjöqvist, F | 1 |
| Gabler, WL; Hubbard, GL | 1 |
| Abbruzzi, R; Arboix, M; Pantarotto, C; Sezzano, P | 1 |
| Hanssen, BR; Lindstrom, TD; Wrighton, SA | 1 |
| Kawaguchi, Y; Komatsu, T; Minami, Y; Nakajima, M; Saeki, M; Shimada, N; Takemoto, K; Yamazaki, H; Yokoi, T | 1 |
| Fujimoto, S; Funakoshi, S; Inagaki, N; Kominato, R; Mukai, E; Nabe, K; Nishi, Y; Seino, Y; Shimodahira, M; Yamada, Y | 1 |
2 review(s) available for phenytoin and nadp
| Article | Year |
|---|---|
Join the microsomal bandwagon.
Topics: Age Factors; Animals; Anthracenes; Carbon Disulfide; Dichlorodiphenyldichloroethane; Endoplasmic Reticulum; Enzyme Induction; Female; Hepatomegaly; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Phospholipids; Protein Biosynthesis; Rats; Sex Factors; Steroids; Testosterone; Transferases | 1970 |
Drug metabolism in the human fetus and newborn infant.
Topics: Aminobenzoates; Anti-Bacterial Agents; Bilirubin; Diazepam; Electron Transport; Endoplasmic Reticulum; Ethers, Cyclic; Female; Fetus; Half-Life; Humans; Infant, Newborn; Liver; Maternal-Fetal Exchange; Microsomes, Liver; NADP; Nortriptyline; Pharmaceutical Preparations; Phenytoin; Pregnancy; Sulfobromophthalein; Testosterone | 1972 |
17 other study(ies) available for phenytoin and nadp
| Article | Year |
|---|---|
Hydroxylation of 5,5-diphenylhydantoin (phenytoin) by dog liver microsomes.
Topics: Animals; Chromatography, Thin Layer; Dogs; Female; Hydroxylation; In Vitro Techniques; Microsomes, Liver; NADP; Phenytoin | 1977 |
Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Hydantoins; Isoenzymes; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenytoin; Polymorphism, Genetic; Stereoisomerism; Warfarin | 1987 |
Conversion of phenytoin to reactive metabolites in rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Radioisotopes; Hydroxylation; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenytoin; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase | 1986 |
An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.
Topics: Adult; Animals; Biotransformation; Cell Survival; Epoxide Hydrolases; Glutathione Transferase; Humans; Imidazoles; Imidazolidines; In Vitro Techniques; Leukocytes, Mononuclear; Male; Mianserin; Mice; Microsomes, Liver; NADP; Phenytoin | 1988 |
Partial purification and characterization of NADPH-linked aldehyde reductase from monkey brain.
Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Aldehydes; Ammonium Sulfate; Animals; Barbiturates; Brain; Brain Stem; Calcium Phosphates; Catechols; Centrifugation, Density Gradient; Chemistry Techniques, Analytical; Chlorpromazine; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycols; Haplorhini; Hydroxyindoleacetic Acid; Kinetics; Medulla Oblongata; Mesencephalon; Molecular Weight; NADP; Phenytoin; Pons; Pyrazoles | 1973 |
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione | 1973 |
Effects of diphenylhydantoin upon estrogen metabolism by liver microsomes of DDT-treated Japanese quail.
Topics: Animals; Coturnix; DDT; Drug Interactions; Estrogens; Female; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; NADP; Organ Size; Phenytoin; Protein Biosynthesis | 1973 |
Metabolism of cortisol-4-C-14 and cortisone-4-C-14 by rat brain homogenates.
Topics: Animals; Brain; Chromatography, Paper; Cortisone; Hydrocortisone; In Vitro Techniques; NADP; Phenytoin; Rats; Subcellular Fractions | 1965 |
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry | 1967 |
Studies on the occurrence of N-demethylase activity in adrenal and hepatic preparations from guinea pigs and rats. The effect of various substances on the magnitude of this activity.
Topics: Adrenal Glands; Animals; DDT; Dichlorodiphenyldichloroethane; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Liver; Male; NAD; NADP; Phenytoin; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Transferases | 1969 |
Kinetic changes in microsomal drug metabolism with age and diphenylhydantoin treatment.
Topics: Age Factors; Aniline Compounds; Animals; Benzphetamine; Cytochromes; Enzyme Induction; Female; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenytoin; Rats | 1970 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
Metabolism in vitro of 5,5-diphenylhydantoin.
Topics: Animals; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; In Vitro Techniques; Liver; NAD; NADP; Phenytoin; Rats | 1972 |
Studies on 5,5-diphenylhydantoin irreversible binding to rat liver microsomal proteins.
Topics: Animals; Chromatography, Gas; Epoxy Compounds; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenytoin; Protein Binding; Rats | 1982 |
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin | 1993 |
Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats.
Topics: Animals; Anticonvulsants; Baculoviridae; Benzene Derivatives; Catechols; Cytochrome P-450 Enzyme System; Drug Interactions; Fluoresceins; Hydroxylation; Male; Microsomes, Liver; NADP; Ouabain; Oxidants; Phenytoin; Rats; Rats, Wistar; Recombinant Proteins | 2001 |
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Calcium; Diazoxide; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potentials; NADP; Phenytoin; Potassium; Quaternary Ammonium Compounds; Rats; Rats, Wistar | 2006 |