phenytoin and nadp

phenytoin has been researched along with nadp in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199016 (84.21)18.7374
1990's1 (5.26)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butler, TC; Dudley, KH; Johnson, D; Mitchell, GN1
Branch, RA; Guengerich, FP; Hall, SD; Wilkinson, GR1
Billings, RE; Milton, SG1
Kitteringham, NR; Lambert, C; Maggs, JL; Park, BK; Riley, RJ1
Bronaugh, RL; Erwin, VG1
Deitrich, RA; Erwin, VG1
Bernstein, JD; Johnson, SL1
MacGee, J; Sholiton, LJ; Werk, EE1
Hagihara, B; Ichikawa, Y; Yamano, T1
Bruggeman, LL; Kupfer, D; Munsell, T1
Becker, BA; Eling, TE; Fouts, JR; Harbison, RD1
Kutt, H; Verebely, K1
Rane, A; Sjöqvist, F1
Gabler, WL; Hubbard, GL1
Abbruzzi, R; Arboix, M; Pantarotto, C; Sezzano, P1
Hanssen, BR; Lindstrom, TD; Wrighton, SA1
Kawaguchi, Y; Komatsu, T; Minami, Y; Nakajima, M; Saeki, M; Shimada, N; Takemoto, K; Yamazaki, H; Yokoi, T1
Fujimoto, S; Funakoshi, S; Inagaki, N; Kominato, R; Mukai, E; Nabe, K; Nishi, Y; Seino, Y; Shimodahira, M; Yamada, Y1

Reviews

2 review(s) available for phenytoin and nadp

ArticleYear
Join the microsomal bandwagon.
    Food and cosmetics toxicology, 1970, Volume: 8, Issue:5

    Topics: Age Factors; Animals; Anthracenes; Carbon Disulfide; Dichlorodiphenyldichloroethane; Endoplasmic Reticulum; Enzyme Induction; Female; Hepatomegaly; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Phospholipids; Protein Biosynthesis; Rats; Sex Factors; Steroids; Testosterone; Transferases

1970
Drug metabolism in the human fetus and newborn infant.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:1

    Topics: Aminobenzoates; Anti-Bacterial Agents; Bilirubin; Diazepam; Electron Transport; Endoplasmic Reticulum; Ethers, Cyclic; Female; Fetus; Half-Life; Humans; Infant, Newborn; Liver; Maternal-Fetal Exchange; Microsomes, Liver; NADP; Nortriptyline; Pharmaceutical Preparations; Phenytoin; Pregnancy; Sulfobromophthalein; Testosterone

1972

Other Studies

17 other study(ies) available for phenytoin and nadp

ArticleYear
Hydroxylation of 5,5-diphenylhydantoin (phenytoin) by dog liver microsomes.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 228, Issue:1

    Topics: Animals; Chromatography, Thin Layer; Dogs; Female; Hydroxylation; In Vitro Techniques; Microsomes, Liver; NADP; Phenytoin

1977
Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1

    Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Hydantoins; Isoenzymes; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenytoin; Polymorphism, Genetic; Stereoisomerism; Warfarin

1987
Conversion of phenytoin to reactive metabolites in rat liver microsomes.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Animals; Biotransformation; Carbon Radioisotopes; Hydroxylation; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenytoin; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase

1986
An in vitro study of the microsomal metabolism and cellular toxicity of phenytoin, sorbinil and mianserin.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:5

    Topics: Adult; Animals; Biotransformation; Cell Survival; Epoxide Hydrolases; Glutathione Transferase; Humans; Imidazoles; Imidazolidines; In Vitro Techniques; Leukocytes, Mononuclear; Male; Mianserin; Mice; Microsomes, Liver; NADP; Phenytoin

1988
Partial purification and characterization of NADPH-linked aldehyde reductase from monkey brain.
    Journal of neurochemistry, 1973, Volume: 21, Issue:4

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Aldehydes; Ammonium Sulfate; Animals; Barbiturates; Brain; Brain Stem; Calcium Phosphates; Catechols; Centrifugation, Density Gradient; Chemistry Techniques, Analytical; Chlorpromazine; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycols; Haplorhini; Hydroxyindoleacetic Acid; Kinetics; Medulla Oblongata; Mesencephalon; Molecular Weight; NADP; Phenytoin; Pons; Pyrazoles

1973
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
    Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20

    Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione

1973
Effects of diphenylhydantoin upon estrogen metabolism by liver microsomes of DDT-treated Japanese quail.
    Bulletin of environmental contamination and toxicology, 1973, Volume: 10, Issue:5

    Topics: Animals; Coturnix; DDT; Drug Interactions; Estrogens; Female; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; NADP; Organ Size; Phenytoin; Protein Biosynthesis

1973
Metabolism of cortisol-4-C-14 and cortisone-4-C-14 by rat brain homogenates.
    Metabolism: clinical and experimental, 1965, Volume: 14, Issue:10

    Topics: Animals; Brain; Chromatography, Paper; Cortisone; Hydrocortisone; In Vitro Techniques; NADP; Phenytoin; Rats; Subcellular Fractions

1965
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
    Archives of biochemistry and biophysics, 1967, Volume: 120, Issue:1

    Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry

1967
Studies on the occurrence of N-demethylase activity in adrenal and hepatic preparations from guinea pigs and rats. The effect of various substances on the magnitude of this activity.
    Archives of biochemistry and biophysics, 1969, Volume: 129, Issue:1

    Topics: Adrenal Glands; Animals; DDT; Dichlorodiphenyldichloroethane; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Liver; Male; NAD; NADP; Phenytoin; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Transferases

1969
Kinetic changes in microsomal drug metabolism with age and diphenylhydantoin treatment.
    European journal of pharmacology, 1970, Jul-01, Volume: 11, Issue:1

    Topics: Age Factors; Aniline Compounds; Animals; Benzphetamine; Cytochromes; Enzyme Induction; Female; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenytoin; Rats

1970
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature

1970
Metabolism in vitro of 5,5-diphenylhydantoin.
    Biochemical pharmacology, 1972, Nov-15, Volume: 21, Issue:22

    Topics: Animals; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; In Vitro Techniques; Liver; NAD; NADP; Phenytoin; Rats

1972
Studies on 5,5-diphenylhydantoin irreversible binding to rat liver microsomal proteins.
    Biochemical pharmacology, 1982, Apr-15, Volume: 31, Issue:8

    Topics: Animals; Chromatography, Gas; Epoxy Compounds; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenytoin; Protein Binding; Rats

1982
Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cytochrome P-450 Enzyme System; Dexamethasone; Erythromycin; Humans; In Vitro Techniques; Macrolides; Male; Microsomes, Liver; NADP; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Troleandomycin

1993
Decreases in phenytoin hydroxylation activities catalyzed by liver microsomal cytochrome P450 enzymes in phenytoin-treated rats.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:4 Pt 1

    Topics: Animals; Anticonvulsants; Baculoviridae; Benzene Derivatives; Catechols; Cytochrome P-450 Enzyme System; Drug Interactions; Fluoresceins; Hydroxylation; Male; Microsomes, Liver; NADP; Ouabain; Oxidants; Phenytoin; Rats; Rats, Wistar; Recombinant Proteins

2001
Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets.
    Endocrinology, 2006, Volume: 147, Issue:6

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Calcium; Diazoxide; Glucose; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potentials; NADP; Phenytoin; Potassium; Quaternary Ammonium Compounds; Rats; Rats, Wistar

2006