phenytoin and n-vinyl-2-pyrrolidinone

phenytoin has been researched along with n-vinyl-2-pyrrolidinone in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's4 (26.67)29.6817
2010's8 (53.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arita, T; Fujiwara, J; Naganuma, T; Nakano, M; Sekikawa, H1
Coovadia, HM; Seager, J; Soothill, JF1
Nagai, T; Sonobe, T; Sugihara, M; Yakou, S; Yamazaki, S1
Kou, JH; Saha, P1
Biggio, G; Franco, M; Latrofa, A; Liso, G; Muggironi, M; Provenzano, MR; Serra, M; Trapani, G; Tullio, C1
Albano, S; Fusaro, F; Mazzotti, M; Meier, U; Muhrer, G1
Haslam, J; Kajiyama, A; McIntosh, MP; Rajewski, RA; Yasuji, T1
Danjo, K; Nakanishi, Y; Niwa, T; Sugimoto, S2
Higashi, K; Ishikawa, T; Kumamoto, T; Limwikrant, W; Moribe, K; Ogino, A; Yamamoto, K1
Danjo, K; Niwa, T1
Reineke, TM; Tale, S; Widanapathirana, L1
Higashi, K; Katakawa, K; Kumamoto, T; Moribe, K; Ohyagi, N; Otsuka, N; Shimizu, K; Ueda, K; Yamamoto, K1
Dumville, JC; Norman, G; Soares, MO; Stubbs, N; Westby, MJ1
Funahashi, I; Ito, Y; Kondo, K; Niwa, T; Yamada, M1

Reviews

1 review(s) available for phenytoin and n-vinyl-2-pyrrolidinone

ArticleYear
Dressings and topical agents for treating pressure ulcers.
    The Cochrane database of systematic reviews, 2017, 06-22, Volume: 6

    Topics: Alginates; Bandages; Bandages, Hydrocolloid; Collagenases; Dermatologic Agents; Egg White; Gels; Glucuronic Acid; Hexuronic Acids; Humans; Network Meta-Analysis; Ointments; Pharmaceutic Aids; Phenytoin; Povidone; Pressure Ulcer; Randomized Controlled Trials as Topic; Wound Healing; Zinc Oxide

2017

Other Studies

14 other study(ies) available for phenytoin and n-vinyl-2-pyrrolidinone

ArticleYear
Dissolution behaviors and gastrointestinal absorption of phenytoin in phenytoin-polyvinylpyrrolidone coprecipitate.
    Chemical & pharmaceutical bulletin, 1978, Volume: 26, Issue:10

    Topics: Animals; Biological Availability; Chemical Precipitation; Humans; Intestinal Absorption; Phenytoin; Povidone; Rabbits

1978
Reduced immunoglobulin concentration and impaired macrophage function in mice due to diphenylhydantoin.
    Clinical and experimental immunology, 1978, Volume: 33, Issue:3

    Topics: Animals; Immunoglobulin A; Immunoglobulin M; Macrophages; Male; Mice; Mice, Inbred CBA; Phenytoin; Povidone

1978
Dissolution and bioavailability of phenytoin in phenytoin-polyvinylpyrrolidone-sodium deoxycholate coprecipitate.
    Chemical & pharmaceutical bulletin, 1986, Volume: 34, Issue:8

    Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Deoxycholic Acid; Male; Phenytoin; Povidone; Rabbits; Solubility; X-Ray Diffraction

1986
Effect of solubilizing excipients on permeation of poorly water-soluble compounds across Caco-2 cell monolayers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 50, Issue:3

    Topics: Alkaloids; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cimetidine; Diltiazem; Excipients; Furans; Humans; Hydrogen-Ion Concentration; Imidazoles; Intestinal Absorption; Naphthalenes; Phenytoin; Piperidines; Poloxamer; Polyethylene Glycols; Povidone; Propranolol; Solubility; Triazoles

2000
Dissolution properties and anticonvulsant activity of phenytoin-polyethylene glycol 6000 and -polyvinylpyrrolidone K-30 solid dispersions.
    International journal of pharmaceutics, 2001, Aug-28, Volume: 225, Issue:1-2

    Topics: Animals; Anticonvulsants; Chemistry, Pharmaceutical; Drug Combinations; Male; Mice; Pharmaceutic Aids; Phenytoin; Povidone; Seizures; Solubility; Spectroscopy, Fourier Transform Infrared

2001
Use of compressed gas precipitation to enhance the dissolution behavior of a poorly water-soluble drug: generation of drug microparticles and drug-polymer solid dispersions.
    International journal of pharmaceutics, 2006, Feb-03, Volume: 308, Issue:1-2

    Topics: Chemical Precipitation; Crystallization; Gases; Microspheres; Phenytoin; Polymers; Povidone; Pressure; Solubility; Solvents; Surface Properties; Temperature; Time Factors

2006
Preliminary evaluation of polymer-based drug composite microparticle production by coacervate desolvation with supercritical carbon dioxide.
    Journal of pharmaceutical sciences, 2006, Volume: 95, Issue:3

    Topics: Carbon Dioxide; Drug Compounding; Ethanol; Hexanes; Microscopy, Electron, Scanning; Particle Size; Phenytoin; Povidone; X-Ray Diffraction

2006
Development of a novel ultra cryo-milling technique for a poorly water-soluble drug using dry ice beads and liquid nitrogen.
    International journal of pharmaceutics, 2012, Apr-15, Volume: 426, Issue:1-2

    Topics: Adhesiveness; Chemistry, Pharmaceutical; Cold Temperature; Crystallization; Drug Compounding; Dry Ice; Microscopy, Electron, Scanning; Nanotechnology; Nitrogen; Particle Size; Phase Transition; Phenytoin; Povidone; Solubility; Technology, Pharmaceutical; Transition Temperature; Zirconium

2012
Novel ultra-cryo milling and co-grinding technique in liquid nitrogen to produce dissolution-enhanced nanoparticles for poorly water-soluble drugs.
    Chemical & pharmaceutical bulletin, 2012, Volume: 60, Issue:3

    Topics: Cellulose; Drug Compounding; Hypromellose Derivatives; Methylcellulose; Nanoparticles; Nitrogen; Particle Size; Phenytoin; Povidone; Powders; Solubility; Water; X-Ray Diffraction

2012
Mechanism of nanoparticle formation from ternary coground phenytoin and its derivatives.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:9

    Topics: Chemistry, Pharmaceutical; Crystallization; Drug Stability; Magnetic Resonance Spectroscopy; Methylation; Microscopy, Atomic Force; Nanoparticles; Nanotechnology; Particle Size; Phenytoin; Povidone; Sodium Dodecyl Sulfate; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Water

2012
Design of self-dispersible dry nanosuspension through wet milling and spray freeze-drying for poorly water-soluble drugs.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Nov-20, Volume: 50, Issue:3-4

    Topics: Freeze Drying; Nanoparticles; Particle Size; Phenytoin; Povidone; Sodium Dodecyl Sulfate; Solubility; Suspensions; Technology, Pharmaceutical; Water

2013
Dissolution and Solubility Enhancement of the Highly Lipophilic Drug Phenytoin via Interaction with Poly(N-isopropylacrylamide-co-vinylpyrrolidone) Excipients.
    Molecular pharmaceutics, 2015, Jul-06, Volume: 12, Issue:7

    Topics: Acrylamides; Anticonvulsants; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Excipients; Hydrogen Bonding; Phenytoin; Polymers; Pyrrolidinones; Solubility; Solutions; Temperature; Water; X-Ray Diffraction

2015
An Insight into Different Stabilization Mechanisms of Phenytoin Derivatives Supersaturation by HPMC and PVP.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:8

    Topics: Anticonvulsants; Caco-2 Cells; Cell Membrane Permeability; Drug Compounding; Drug Stability; Enterocytes; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Intestinal Absorption; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Models, Chemical; Molecular Structure; Phenytoin; Povidone; Solubility; Solutions

2015
Novel contamination-free wet milling technique using ice beads for poorly water-soluble compounds.
    International journal of pharmaceutics, 2019, May-30, Volume: 563

    Topics: Desiccation; Drug Compounding; Drug Liberation; Ice; Phenytoin; Povidone; Sodium Dodecyl Sulfate; Solubility; Water; Zirconium

2019