phenytoin and morphine

phenytoin has been researched along with morphine in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (61.43)	18.7374
1990's	5 (7.14)	18.2507
2000's	10 (14.29)	29.6817
2010's	12 (17.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Jolivette, LJ; Ward, KW	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bissada, NK; Finkbeiner, AE; Welch, LT	1
Ratcliffe, FG	1
Katz, RJ; Schmaltz, K	1
Holtzman, JL; Leute, RK; Montgomery, MR	1
Clouet, DH; O'Callaghan, JP; Williams, N	1
Glogner, P	1
Brocco, MJ; Killam, KF; Robinson, CA	1
Bhattacharya, SK; Ghosal, S; Reddy, PK; Sharma, PV; Singh, AK	1
Bennett, WM; Olsen, GD; Porter, GA	1
Gibson, TC	1
Spiehler, V	1
Gregory, ER; Grossman, S; Sheidler, VR	1
Lucas, ML; McEwan, GT	1
Sayo, H	1
Kaneda, H; Kaneto, H; Kawatani, S	1
Passananti, GT; Vessell, ES	1
Cadden, JJ; Feigelson, EB	1
Ganshorn, A; Kurz, H	1
Greengard, P; Quinn, GP; Reid, MB	1
Oswald, I	1
Oldendorf, WH	1
Fertziger, AP; Lynch, JJ; Stein, EA	1
McBay, AJ	1
Andersen, PR; Gibbs, P; Kubinski, H	1
Vorherr, H	1
Chau-Wong, M; Moyyen, S; Seeman, P	1
Cimbura, G; Kofoed, J	1
Krsiak, M; Steinberg, H	1
Hatch, RC	1
Collins, VJ	1
Ball, JC; Urbaitis, JC	1
Koe, BK; Weissman, A	1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN	1
Mulé, SJ	1
de Carolis, AS; Longo, VG	1
Banfi, S; Consonni, P; Diena, A; Pifferi, G	1
Hamacher, J; Zipf, HF	1
Fathi, MM	1
Copeland, ES; Yang, GC	1
Foong, FW; Satoh, M; Takagi, H	1
Cookson, SL; Mann, JD	1
Gautieri, RF; Mahalik, MP; McDevitt, JM; Russell, JA	1
Goldbaum, L	1
Banks, D; Bloomfield, SM; Cline, S; Kaufman, HH; Sauter, K	1
Hirohashi, M; Kitano, Y; Nomura, M; Takasuna, K; Usui, C	1
Chivell, W; Fearnside, M; Kennedy, MC; Moran, JL; Morris, RG; Tobin, B; Upton, RN	1
HARVEY, P	1
Aykac, B; Koner, O; Mercan, A; Türe, H; Türe, U	1
Aykac, B; Bingol, CA; Karlikaya, G; Sayin, M; Türe, H; Türe, U	1
Gottschalk, A	1
Chou, D; Lee, HY; Pang, SM; Thirumoorthy, T	1
Betnér, I; Briem, S; Bueters, T; Dahlström, J; Kvalvågnaes, K	1
Moling, O; Perino, F; Piccin, A	1
Beukers, MW; Danhof, M; de Lange, ECM; Huntjens, DR; Kokki, H; Kokki, M; Krauwinkel, W; Proost, JH; Välitalo, PA; van Hasselt, JGC; Vermeulen, A; Wong, YC; Yamamoto, Y	1

Reviews

9 review(s) available for phenytoin and morphine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Uropharmacology: X. Central nervous system stimulants and depressants. Urology, 1979, Volume: 13, Issue:4 Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract	1979
Radioimmunoassay. Recent advances in clinical nuclear medicine, 1975, Volume: 1 Topics: Adrenocorticotropic Hormone; Aldosterone; alpha-Fetoproteins; Angiotensin II; Carcinoembryonic Antigen; Digoxin; Electronic Data Processing; Estradiol; Factor VIII; Ferritins; Hepatitis B Antigens; Humans; Immunoglobulins; Insulin; Intrinsic Factor; Isotope Labeling; Luteinizing Hormone; Morphine; Parathyroid Hormone; Phenytoin; Placental Lactogen; Quality Control; Radioimmunoassay; Thyrotropin	1975
The heart in myasthenia gravis. American heart journal, 1975, Volume: 90, Issue:3 Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography	1975
Utility of clinical chemical determinations of drug concentrations in biological fluids. Clinical chemistry, 1971, Volume: 17, Issue:9 Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays	1971
Drugs and sleep. Pharmacological reviews, 1968, Volume: 20, Issue:4 Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan	1968
Toxicological findings in fatal poisonings. Clinical chemistry, 1973, Volume: 19, Issue:4 Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordiazepoxide; Dextropropoxyphene; Diazepam; Ethchlorvynol; Glutethimide; Heroin; Humans; Meprobamate; Methadone; Methanol; Morphine; Orphenadrine; Paraldehyde; Pentazocine; Phenothiazines; Phenytoin; Poisoning; Quinine; Salicylates; Toxicology; Tranquilizing Agents	1973
Drug excretion in breast milk. Postgraduate medicine, 1974, Volume: 56, Issue:4 Topics: Anti-Bacterial Agents; Barbiturates; Biological Transport, Active; Breast; Breast Feeding; Caffeine; Chloramphenicol; Contraceptives, Oral; Coumarins; Female; Fluorine; Humans; Hydrogen-Ion Concentration; Infant; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Lactation; Meprobamate; Milk, Human; Models, Biological; Morphine; Nicotine; Pesticides; Pharmaceutical Preparations; Phenytoin; Potassium Iodide; Pregnancy; Salicylates; Sulfonamides; Time Factors	1974
Psychopharmacological aspects of aggression: a review of the literature and some new experiments. Journal of psychosomatic research, 1969, Volume: 13, Issue:3 Topics: Aggression; Amobarbital; Animals; Barbiturates; Bees; Behavior, Animal; Cats; Chlordiazepoxide; Chlorpromazine; Escape Reaction; Ethanol; Haplorhini; Humans; Lysergic Acid Diethylamide; Male; Mescaline; Mice; Morphine; Parasympatholytics; Peptides; Phenytoin; Territoriality; Venoms	1969

Trials

2 trial(s) available for phenytoin and morphine

Article	Year
Drugs and sleep. Pharmacological reviews, 1968, Volume: 20, Issue:4 Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan	1968
The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study. Anesthesia and analgesia, 2009, Volume: 109, Issue:5 Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Fatigue; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intubation, Intratracheal; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Piperidines; Preanesthetic Medication; Propofol; Prospective Studies; Remifentanil; Sleep; Supratentorial Neoplasms; Time Factors; Treatment Outcome	2009

Article

Year

Drugs and sleep.

Pharmacological reviews, 1968, Volume: 20, Issue:4

Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968

The analgesic effect of gabapentin as a prophylactic anticonvulsant drug on postcraniotomy pain: a prospective randomized study.

Anesthesia and analgesia, 2009, Volume: 109, Issue:5

Topics: Administration, Oral; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Fatigue; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Intubation, Intratracheal; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Piperidines; Preanesthetic Medication; Propofol; Prospective Studies; Remifentanil; Sleep; Supratentorial Neoplasms; Time Factors; Treatment Outcome

2009

Other Studies

60 other study(ies) available for phenytoin and morphine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Facilitation of opiate- and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine. Psychopharmacology, 1979, Volume: 65, Issue:1 Topics: Animals; Carbamazepine; Drug Synergism; Endorphins; Enkephalins; Habituation, Psychophysiologic; Male; Mice; Morphine; Motor Activity; Narcotics; Phenytoin; Time Factors	1979
Application of electron spin resonance to determination of serum drug concentrations. Clinical chemistry, 1975, Volume: 21, Issue:9 Topics: Antigen-Antibody Reactions; Autoanalysis; Chromatography, Gas; Chromatography, Thin Layer; Dialysis; Electron Spin Resonance Spectroscopy; Evaluation Studies as Topic; Humans; Immunoassay; Methods; Morphine; Phenytoin; Spin Labels; Ultrafiltration	1975
The effect of opiates on endogenous phosphorylation of proteins in the synaptic plasma membranes of rat striatum. Progress in clinical and biological research, 1979, Volume: 27 Topics: Animals; Corpus Striatum; Drug Tolerance; Illicit Drugs; Male; Methadone; Morphine; Naloxone; Narcotics; Nerve Tissue Proteins; Phenytoin; Phosphorylation; Protein Kinases; Rats; Synaptic Membranes	1979
[Radioimmunologic methods of drug analysis]. Der Internist, 1975, Volume: 16, Issue:3 Topics: Amphetamine; Animals; Antibody Formation; Barbiturates; Biguanides; Dexamethasone; Diazepam; Digitoxin; Digoxin; Gentamicins; Glyburide; Morphine; Pentazocine; Phenytoin; Prostaglandins; Protein Binding; Rabbits; Radioimmunoassay; Tubocurarine	1975
Evaluation of narcotic and narcotic antagonist interactions in primates. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration	1976
Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin. Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:10 Topics: Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Central Nervous System; Depression, Chemical; Drug Interactions; Glucosides; Glycosides; Hexobarbital; Iridoid Glucosides; Mice; Morphine; Motor Skills; Phenytoin; Plant Extracts; Plants, Medicinal; Pyrans; Pyrones; Rats; Sleep; Xanthenes; Xanthones	1976
Morphine and phenytoin binding to plasma proteins in renal and hepatic failure. Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:6 Topics: Bilirubin; Blood Proteins; Creatinine; Humans; Jaundice; Kidney Failure, Chronic; Kidney Transplantation; Liver Diseases; Morphine; Phenytoin; Protein Binding; Renal Dialysis; Serum Albumin; Uremia	1975
Drugs of abuse radioimmunoassay directory. Clinical toxicology, 1975, Volume: 8, Issue:2 Topics: Amphetamine; Atropine; Barbiturates; Cannabis; Humans; Lysergic Acid Diethylamide; Mescaline; Morphine; Nicotine; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Radioimmunoassay; Substance-Related Disorders	1975
Grand mal seizures associated with high-dose intravenous morphine infusions: incidence and possible etiology. Pain, 1992, Volume: 51, Issue:2 Topics: Adult; Aged; Epilepsy, Tonic-Clonic; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Morphine; Neoplasms; Pain, Intractable; Phenytoin; Retrospective Studies	1992
The effect of E. coli STa enterotoxin on the absorption of weakly dissociable drugs from rat proximal jejunum in vivo. British journal of pharmacology, 1990, Volume: 101, Issue:4 Topics: Amphetamine; Animals; Bacterial Toxins; Colforsin; Electrolytes; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Lidocaine; Male; Morphine; Perfusion; Phenytoin; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Theophylline	1990
[Spin immunoassay]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1987, Issue:31 Suppl Topics: Electron Spin Resonance Spectroscopy; Humans; Immunoassay; Morphine; Phenobarbital; Phenytoin; Testosterone	1987
Differentiation of alcohol and barbital physical dependence. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:2 Topics: Animals; Barbital; Barbiturates; Diazepam; Ethanol; Ethosuximide; Male; Mice; Morphine; Naloxone; Pentylenetetrazole; Phenytoin; Substance Withdrawal Syndrome	1986
Changing patterns of drug abuse in New York City. The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3 Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders	1974
[Differences between the protein binding of newborns and adults and their importance for pharmacological action]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental	1968
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism. Molecular pharmacology, 1966, Volume: 2, Issue:4 Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine	1966
Brain uptake of metabolites and drugs following carotid arterial injections. Transactions of the American Neurological Association, 1971, Volume: 96 Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats	1971
Letter: Suppression of morphine-induced mania in cats. Psychopharmacologia, 1974, Apr-08, Volume: 36, Issue:2 Topics: Animals; Behavior, Animal; Cats; Female; Locomotion; Male; Morphine; Phenytoin; Vocalization, Animal	1974
Effects of neuropharmacological agents on in vitro formation of complexes between nucleic acids and proteins. Neuropharmacology, 1974, Volume: 13, Issue:2 Topics: Animals; Benztropine; Cattle; Chlorpromazine; Codeine; Desipramine; DNA, Bacterial; Escherichia coli; Histones; Lysergic Acid Diethylamide; Morphine; Neostigmine; Nucleic Acids; Orphenadrine; Phenytoin; Protein Binding; Proteins; RNA, Bacterial; RNA, Ribosomal; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Trihexyphenidyl	1974
The membrane binding of morphine, diphenylhydantoin, and tetrahydrocannabinol. Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:12 Topics: Adenosine Triphosphate; Animals; Brain; Cannabis; Carbon Isotopes; Cell Membrane; Dinitrophenols; Dronabinol; Erythrocytes; Guinea Pigs; Humans; In Vitro Techniques; Membranes; Morphine; Nerve Endings; Neural Conduction; Ouabain; Phenytoin; Saponins; Synaptic Vesicles; Synaptosomes; Temperature; Time Factors	1972
A review of some GLD-FID derivitization techniques found useful in forensic toxicology. Journal of chromatographic science, 1974, Volume: 12, Issue:5 Topics: Acetylation; Amphetamine; Bromides; Chromatography, Gas; Forensic Medicine; Formaldehyde; Glycols; Humans; Methadone; Methylation; Morphine; Oxidation-Reduction; Phenytoin; Toxicology	1974
Effect of drugs on catnip (Nepeta cataria)-induced pleasure behavior in cats. American journal of veterinary research, 1972, Volume: 33, Issue:1 Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Cats; Chlorpheniramine; Chlorpromazine; Drug Synergism; Female; Hexamethonium Compounds; Histidine; Lactones; Magnoliopsida; Male; Mecamylamine; Methysergide; Morphine; Neostigmine; Phenytoin; Physostigmine; Pilocarpine; Plant Extracts; Propranolol; Pyrans; Salivation; Serotonin; Sexual Behavior, Animal	1972
Advances in pharmacology related to anesthesia and surgery. Industrial medicine & surgery, 1966, Volume: 35, Issue:6 Topics: Anesthesia; Cardiovascular System; Central Nervous System; Digestive System; Drug Therapy; General Surgery; Humans; Kidney; Meperidine; Morphine; Pharmacology; Phenytoin; Respiratory System	1966
Absence of major medical complications among chronic opiate addicts. The British journal of addiction to alcohol and other drugs, 1970, Volume: 65, Issue:2 Topics: Age Factors; Aged; Codeine; Heroin; Humans; Injections; Male; Methadone; Middle Aged; Morphine; Opium; Patient Readmission; Phenytoin; Substance-Related Disorders; Time Factors	1970
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea	1967
Aconitine-induced writhing: a method for assessment of analgesic activity. Japanese journal of pharmacology, 1969, Volume: 19, Issue:1 Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate	1969
Routine identification of drugs of abuse in human urine. I. Application of fluorometry, thin-layer and gas-liquid chromatography. Journal of chromatography, 1971, Mar-03, Volume: 55, Issue:2 Topics: Amphetamine; Analgesics; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Glutethimide; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Indicators and Reagents; Morphinans; Morphine; Phenothiazines; Phenytoin; Psychopharmacology; Quinine; Substance-Related Disorders; Tranquilizing Agents	1971
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam). Arzneimittel-Forschung, 1967, Volume: 17, Issue:12 Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine	1967
2,3-benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines. Journal of medicinal chemistry, 1969, Volume: 12, Issue:2 Topics: Analgesia; Animals; Aspirin; Ataxia; Barbiturates; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Exploratory Behavior; Male; Meprobamate; Mice; Morphine; Motor Activity; Muscles; Oxazines; Phenytoin; Pyridones; Rats; Reflex; Seizures	1969
[Combination effects. 2. Experimental conception and presentation of combination effects]. Arzneimittel-Forschung, 1966, Volume: 16, Issue:3 Topics: Drug Synergism; Models, Chemical; Morphine; Penicillins; Phenobarbital; Phenytoin; Streptomycin	1966
Effect of drugs on brain acetylcholine level in Gerbillus pyramidum. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 74, Issue:1 Topics: Acetylcholine; Animals; Behavior, Animal; Brain; Female; Gerbillinae; Male; Meprobamate; Methamphetamine; Morphine; Pentobarbital; Phenobarbital; Phenytoin; Reserpine	1983
Spin immunoassay. Methods in enzymology, 1981, Volume: 74 Pt C Topics: Blood Proteins; Cocaine; Dronabinol; Electron Spin Resonance Spectroscopy; Humans; Immunoassay; Morphine; Narcotics; Pharmaceutical Preparations; Phenytoin; Progesterone; Saliva; Spin Labels	1981
A newly devised reliable method for evaluating analgesic potencies of drugs on trigeminal pain. Journal of pharmacological methods, 1982, Volume: 7, Issue:4 Topics: Analgesics; Animals; Bradykinin; Carbamazepine; Dental Pulp; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Male; Morphine; Phenytoin; Rats; Rats, Inbred Strains; Time Factors; Trigeminal Neuralgia	1982
Phenytoin reversal and prevention of morphine-induced catalepsy in the rat. Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:5 Topics: Animals; Brain; Catalepsy; Humans; Morphine; Naloxone; Pharmaceutical Vehicles; Phenytoin; Rats	1980
Nonvariance of LD50 values of drugs in gravid and nongravid mice. Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:2 Topics: Animals; Cobalt; Female; Lethal Dose 50; Male; Mice; Morphine; Phenytoin; Pregnancy; Pregnancy, Animal; Toxicology	1980
Schematic procedure for the determination of drugs in body fluids. Clinical toxicology, 1980, Volume: 17, Issue:2 Topics: Amphetamine; Body Fluids; Chromatography, Gas; Fluorometry; Humans; Morphine; Pharmaceutical Preparations; Phenytoin; Spectrophotometry, Ultraviolet	1980
Treatment of high-dose intrathecal morphine overdose. Case report. Journal of neurosurgery, 1994, Volume: 81, Issue:1 Topics: Drug Overdose; Female; Humans; Infusion Pumps; Injections, Spinal; Middle Aged; Morphine; Naloxone; Nitroprusside; Phenytoin; Status Epilepticus	1994
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice. Journal of pharmacological and toxicological methods, 1996, Volume: 35, Issue:1 Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid	1996
Drugs and brain death. The Medical journal of Australia, 1996, Oct-07, Volume: 165, Issue:7 Topics: Adult; Australia; Brain Death; Brain Injuries; Cause of Death; Coroners and Medical Examiners; Epilepsy; Euthanasia, Passive; Humans; Illicit Drugs; Male; Morphine; Phenytoin	1996
DRUG REACTIONS INVOLVING THE ALIMENTARY TRACT. The Medical journal of Australia, 1964, Feb-15, Volume: 1 Topics: Anticoagulants; Bismuth; Chemical and Drug Induced Liver Injury; Chlorothiazide; Drug Therapy; Esophagus; Gastroenterology; Hepatitis; Intestinal Diseases; Mercury Poisoning; Morphine; Mouth; Pancreas; Phenylbutazone; Phenytoin; Reserpine; Salicylates; Steroids; Stomach; Tooth; Toxicology	1964
The effects of propofol infusion on hepatic and pancreatic function and acid-base status in children undergoing craniotomy and receiving phenytoin. Anesthesia and analgesia, 2009, Volume: 109, Issue:2 Topics: Acid-Base Equilibrium; Analgesics, Opioid; Anesthetics, Intravenous; Anticonvulsants; Bilirubin; Blood Gas Analysis; Blood Transfusion; Child; Child, Preschool; Craniotomy; Female; Humans; Injections, Intravenous; Kidney Function Tests; Liver; Liver Function Tests; Male; Morphine; Phenytoin; Propofol; Supratentorial Neoplasms; Triglycerides	2009
Craniotomy pain: trying to do better. Anesthesia and analgesia, 2009, Volume: 109, Issue:5 Topics: Administration, Oral; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anticonvulsants; Craniotomy; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; Pain Measurement; Pain, Postoperative; Phenytoin; Preanesthetic Medication; Supratentorial Neoplasms; Time Factors; Treatment Outcome	2009
Acute generalized exanthematous pustulosis: analysis of cases managed in a tertiary hospital in Singapore. International journal of dermatology, 2010, Volume: 49, Issue:5 Topics: Acute Generalized Exanthematous Pustulosis; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Eruptions; Female; Hospitals, Urban; Humans; Male; Middle Aged; Morphine; Phenytoin; Retrospective Studies; Singapore; Treatment Outcome	2010
High-throughput analysis of standardized pharmacokinetic studies in the rat using sample pooling and UPLC-MS/MS. Journal of pharmaceutical and biomedical analysis, 2011, Jul-15, Volume: 55, Issue:5 Topics: Administration, Oral; Animals; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Diclofenac; Ions; Lactones; Male; Mass Spectrometry; Morphine; Phenytoin; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Sulfones	2011
Acute generalized exanthematous pustulosis with overlap features of toxic epidermal necrolysis/Stevens-Johnson syndrome. International journal of dermatology, 2014, Volume: 53, Issue:1 Topics: Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Drug Eruptions; Female; Humans; Male; Morphine; Phenytoin	2014
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jan-15, Volume: 112 Topics: Acetaminophen; Animals; Biological Transport; Brain; Brain Injuries, Traumatic; Central Nervous System Agents; Epilepsy; Humans; Models, Biological; Morphine; Oxycodone; Phenytoin; Rats	2018