phenytoin and metyrapone

phenytoin has been researched along with metyrapone in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (78.57)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (21.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brooks, MH; Lawrence, AM; Paloyan, E; Prinz, RA	1
Marshall, JS; Tompkins, LS	1
Choi, Y; Sholiton, LJ; Thrasher, K; Werk, EE	1
Rinne, UK	1
Asfeldt, VH; Buhl, J	1
Jubiz, W; Matsukura, S; Meikle, AW; Tyler, FH; West, CD	1
Jubiz, W; Levinson, RA; Meikle, AW; Tyler, FH; West, CD	1
Jubiz, W; Meikle, AW; Tyler, FH; West, CD	1
Garattini, S; Szalay, KS; Szeberenyi, S	1
Garattini, S; Szeberenyi, S; Tacconi, MT	1
Elias, AN; Gwinup, G	1

Reviews

2 review(s) available for phenytoin and metyrapone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effects of some clinically encountered drugs on steroid synthesis and degradation. Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids	1980

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Effects of some clinically encountered drugs on steroid synthesis and degradation.

Metabolism: clinical and experimental, 1980, Volume: 29, Issue:6

Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Drug Interactions; Ethanol; Fetus; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hydroxycholecalciferols; Liver; Metyrapone; Mitotane; Phenobarbital; Phenytoin; Rifampin; Spironolactone; Steroids

1980

Other Studies

12 other study(ies) available for phenytoin and metyrapone

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
The continued importance of adrenalectomy in the treatment of Cushing's disease. Archives of surgery (Chicago, Ill. : 1960), 1979, Volume: 114, Issue:4 Topics: Adolescent; Adrenalectomy; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hypophysectomy; Male; Metyrapone; Middle Aged; Mitotane; Phenytoin; Radiotherapy	1979
Effect of o,p'-DDD and similar compounds on thyroxine binding globulin. The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:3 Topics: Alpha-Globulins; Autoradiography; Blood Protein Electrophoresis; Cellulose; Dichlorodiphenyldichloroethane; Humans; Metyrapone; Phenytoin; Pituitary-Adrenal Function Tests; Protein Binding; Thyroxine-Binding Proteins	1968
Failure of metyrapone to inhibit 11-hydroxylation of 11-deoxycortisol during drug therapy. The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:9 Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Chromatography, Paper; Chromatography, Thin Layer; Cushing Syndrome; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Metyrapone; Phenobarbital; Phenytoin; Pituitary Function Tests; Secretory Rate; Steroids	1967
Site of the inhibiting action of diphenylhydantoin on the release of corticotrophin in epileptic patients. Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:5 Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Epilepsy, Tonic-Clonic; Female; Humans; Hypothalamo-Hypophyseal System; Male; Metyrapone; Phenytoin; Pituitary Gland; Vasopressins	1967
Inhibitory effect of diphenylhydantoin on the feedback control of corticotrophin release. Acta endocrinologica, 1969, Volume: 61, Issue:3 Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Depression, Chemical; Dexamethasone; Epilepsy; Feedback; Female; Humans; Hypothalamo-Hypophyseal System; Male; Metyrapone; Middle Aged; Phenytoin; Pituitary-Adrenal System	1969
Effect of diphenylhydantoin on the metabolism of metyrapone and release of ACTH in man. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12 Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Depression, Chemical; Epilepsy; Humans; Hydrocortisone; Intestinal Absorption; Metyrapone; Mixed Function Oxygenases; Phenytoin; Pyrogens; Tritium	1969
Absorption and conjugation of metyrapone during diphenylhydantoin therapy: mechanism of the abnormal response to oral metyrapone. Endocrinology, 1970, Volume: 86, Issue:2 Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Animals; Biotransformation; Enzyme Induction; Intestinal Absorption; Liver; Male; Metyrapone; Microscopy, Electron; Microsomes; Mixed Function Oxygenases; Phenytoin; Portal Vein; Rats; Vena Cava, Superior	1970
Dilantin and metyrapone: a clinically significant example of enzyme induction. Transactions of the American Clinical and Climatological Association, 1970, Volume: 81 Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Animals; Depression, Chemical; Endoplasmic Reticulum; Enzyme Induction; Epilepsy; Estrogens; Glucuronates; Humans; Hyperplasia; Hypopituitarism; Liver; Metyrapone; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Pituitary Function Tests; Pyrogens; Rats	1970
Removal of plasma metyrapone in rats submitted to previous pharmacological treatment. The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:3 Topics: Animals; Diazepam; Female; Hydrocortisone; Liver; Meprobamate; Metyrapone; Nikethamide; Pentaerythritol Tetranitrate; Phenobarbital; Phenylbutazone; Phenytoin; Rats	1969
Increased metabolism of metyrapone in rats pretreated with diphenylhydantoin or phenobarbital. Endocrinology, 1969, Volume: 85, Issue:3 Topics: Adrenal Glands; Animals; Biotransformation; Chromatography, Thin Layer; Enzyme Induction; Epilepsy; Liver; Metyrapone; Microsomes; Phenobarbital; Phenytoin; Pituitary Function Tests; Rats; Stimulation, Chemical	1969