phenytoin has been researched along with metronidazole in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (37.93) | 18.7374 |
| 1990's | 2 (6.90) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 13 (44.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Jones, JH | 1 |
| Hawkins, DF | 1 |
| Dehne, M; el Abed, K; Hofmann, W; Kroh, U; Lennartz, H | 1 |
| Blyden, GT; Greenblatt, DJ; Scavone, JM | 1 |
| Gugler, R; Jensen, JC | 1 |
| Blume, S; Kaplan, R; Pitrelli, J; Rosenberg, S; Turner, WJ | 1 |
| Gajewska, M | 1 |
| Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A | 1 |
| Picard, EH | 1 |
| Ayres, J; Kinsella, H | 1 |
| Brøsen, K; Dalhoff, K; Flachs, H; Loft, S; Poulsen, HE; Ranek, L; Wantzin, P | 1 |
| Chosidow, O; Cribier, B | 1 |
| Matsumoto, H; Ugawa, Y | 1 |
| Adi, M; Schattner, A | 1 |
2 review(s) available for phenytoin and metronidazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Lichen].
Topics: Adrenal Cortex Hormones; Cyclosporine; Dapsone; Griseofulvin; Humans; Immunosuppressive Agents; Lichen Planus; Metronidazole; Phenytoin; PUVA Therapy; Retinoids | 1997 |
2 trial(s) available for phenytoin and metronidazole
| Article | Year |
|---|---|
Metronidazole impairs clearance of phenytoin but not of alprazolam or lorazepam.
Topics: Adult; Alprazolam; Drug Interactions; Female; Humans; Lorazepam; Male; Metronidazole; Phenytoin; Random Allocation | 1988 |
Phenytoin, Metronidazole and multivitamins in the treatment of alcoholism.
Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Follow-Up Studies; Hospitalization; Hospitals, Psychiatric; Humans; Male; Metronidazole; Middle Aged; Phenytoin; Prognosis; Psychological Tests; Vitamins | 1972 |
25 other study(ies) available for phenytoin and metronidazole
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk | 1977 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gingival Hypertrophy; Gingival Neoplasms; Gingivitis; Gingivitis, Necrotizing Ulcerative; Granuloma, Giant Cell; Herpesviridae Infections; Humans; Leukemia, Myeloid; Metronidazole; Oral Hygiene; Oral Manifestations; Penicillins; Periodontal Abscess; Periodontitis; Phenytoin; Toothbrushing | 1975 |
Teratogens in the human: current problems.
Topics: Abnormalities, Drug-Induced; Barbiturates; Contraceptives, Oral; Ethanol; Female; Fetal Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metronidazole; Phenytoin; Pregnancy; Smoking; Sulfonamides; Teratogens; Tranquilizing Agents | 1976 |
[Dosage adjustment of drugs during continuous hemofiltration. Results and practical consequences of a prospective clinical study].
Topics: Adult; Aged; Cefotaxime; Ceftazidime; Digitoxin; Digoxin; Hemofiltration; Humans; Imipenem; Kidney Failure, Chronic; Metronidazole; Middle Aged; Netilmicin; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Theophylline; Tobramycin; Vancomycin | 1989 |
Interaction between metronidazole and drugs eliminated by oxidative metabolism.
Topics: Administration, Oral; Adult; Antipyrine; Chromatography, Gas; Diazepam; Drug Interactions; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Male; Metronidazole; Phenytoin | 1985 |
Complexometric determination of various diazole derivatives with cupric picrate.
Topics: Aminopyrine; Antipyrine; Azoles; Copper; Histamine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Methods; Metronidazole; Phenylbutazone; Phenytoin; Picrates; Structure-Activity Relationship; Tolazoline | 1972 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
Side effects of metronidazole.
Topics: Humans; Metronidazole; Phenytoin | 1983 |
Multiple cerebral abscesses in an adult with cystic fibrosis.
Topics: Adult; Ampicillin; Brain Abscess; Cystic Fibrosis; Female; Floxacillin; Humans; Metronidazole; Phenytoin | 1982 |
Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis.
Topics: Adult; Aged; Antipyrine; Chemical and Drug Induced Liver Injury; Complement C3; Female; Halothane; HLA Antigens; Humans; Male; Mephenytoin; Metronidazole; Middle Aged; Phenotype; Phenytoin; Polymorphism, Genetic; Sparteine | 1993 |
[Drug induced peripheral neuropathy].
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-HIV Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Antiprotozoal Agents; Antirheumatic Agents; Antitubercular Agents; Colchicine; Gout Suppressants; Humans; Immunosuppressive Agents; Infliximab; Interferon-alpha; Metronidazole; Peripheral Nervous System Diseases; Phenytoin; Tacrolimus | 2012 |
All in his head: an unexpected space-occupying lesion.
Topics: Aged; Anti-Infective Agents; Anticonvulsants; Brain Abscess; Ceftriaxone; Craniotomy; Drainage; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Metronidazole; Paresis; Phenytoin; Streptococcal Infections; Tomography, X-Ray Computed; Viridans Streptococci | 2014 |