phenytoin and methoxsalen

phenytoin has been researched along with methoxsalen in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hueg, B; Staberg, B1
Gerber, N; Hilliard, JB; Mays, DC; Nawoot, S; Pacula, CM1
Florek-Luszczki, M; Glensk, M; Glowniak, K; Luszczki, JJ; Pyrka, D; Skalicka-Wozniak, K; Zagaja, M1
Del Priore, G; Gartrell, BA; Retter, A; Roach, M; Scher, HI; Sokol, GH1
Chung, V; Hartley, ML; Kim, DW; Kim, S; Noel, MS; Ocean, AJ; Philip, PA; Picozzi, VJ; Staszewski, H; Van Tornout, JM; Wang-Gillam, A; Wong, S1

Reviews

1 review(s) available for phenytoin and methoxsalen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for phenytoin and methoxsalen

ArticleYear
Phase II trial of SM-88, a cancer metabolism based therapy, in non-metastatic biochemical recurrent prostate cancer.
    Investigational new drugs, 2021, Volume: 39, Issue:2

    Topics: Aged; Aged, 80 and over; Androgen Antagonists; Humans; Kaplan-Meier Estimate; Male; Methoxsalen; Middle Aged; Neoplasm Recurrence, Local; Phenytoin; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Sirolimus; Tyrosine

2021
A randomized phase II study of SM-88 plus methoxsalen, phenytoin, and sirolimus in patients with metastatic pancreatic cancer treated in the second line and beyond.
    Cancer medicine, 2022, Volume: 11, Issue:22

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Humans; Methoxsalen; Pancreatic Neoplasms; Phenytoin; Quality of Life; Sirolimus

2022

Other Studies

5 other study(ies) available for phenytoin and methoxsalen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Interaction between 8-methoxypsoralen and phenytoin. Consequence for PUVA therapy.
    Acta dermato-venereologica, 1985, Volume: 65, Issue:6

    Topics: Drug Interactions; Epilepsy; Female; Humans; Methoxsalen; Middle Aged; Phenytoin; Psoriasis; PUVA Therapy

1985
Inhibition and induction of drug biotransformation in vivo by 8-methoxypsoralen: studies of caffeine, phenytoin and hexobarbital metabolism in the rat.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:1

    Topics: Animals; Biotransformation; Caffeine; Hexobarbital; Male; Methoxsalen; Phenytoin; Rats; Rats, Inbred Strains

1987
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Fitoterapia, 2015, Volume: 105

    Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid

2015