phenytoin and methotrexate

phenytoin has been researched along with methotrexate in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199025 (49.02)18.7374
1990's2 (3.92)18.2507
2000's11 (21.57)29.6817
2010's12 (23.53)24.3611
2020's1 (1.96)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Jolivette, LJ; Ward, KW1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Andricopulo, AD; Moda, TL; Montanari, CA1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blair, JA; Lei, FH; Lucas, ML; Mangkornthong, P; Swanston, SK1
Lippmann, M1
Aymard, B; Chabot, F; Cornette, A; Delorme, N; Gerard, H; Kheir, A; Lesur, O; Moreau, L; Polu, JM1
Gill, DS; Latham, J; Wickramasinghe, SN1
Weinblatt, ME1
Furst, DE1
Alexander, MS; Balis, FM; Jarosinski, PF; Lesko, LJ; Moscow, JA; Poplack, DG1
Landon, MJ; Morgan, DM; Toothill, VJ1
Whitcomb, ME1
Miller, RW1
Robenberg, IH1
Cain, GD; Rahman, F1
Heischkeil, R1
Roberts, PJ1
Brettner, A; Heitzman, ER; Woodin, WG1
Das, KC; Hoffbrand, AV1
Corcino, JJ; Herbert, V; Waxman, S1
Hepner, GW1
Beckman, DA; Brent, RL1
Scott, JM; Weir, DG1
Haeckel, R; Haindl, H; Oellerich, M1
Albani, F; Baruzzi, A; Bollini, C; Bollini, P; Cacciari, L; Ida, N; Riva, R1
Evans, MA1
Barnes, HM; Prchal, JT; Scott, CW1
Blair, JA; Lucas, ML; Swanston-Flatt, SK1
RAWSON, AJ; YANOFF, M1
Hart, C; Kinney, MO; McCarron, MO1
Davis, K; Fabian, E; Greenhaw, J; Groeters, S; Herold, M; Kamp, H; Looser, R; Marxfeld, H; Mattes, W; Mellert, W; Moeller, N; Montoya-Parra, G; Prokoudine, A; Strauss, V; van Ravenzwaay, B; Walk, T1
Abudunia, AM; Akachar, J; Alaoui, K; Guerrab, W; Ibrahimi, A; Jemli, ME; Ouaabou, R; Ramli, Y1

Reviews

7 review(s) available for phenytoin and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pulmonary reactions to drugs.
    The Medical clinics of North America, 1977, Volume: 61, Issue:6

    Topics: Adrenal Cortex Hormones; Aged; Aminoglycosides; Bleomycin; Busulfan; Contraceptives, Oral; Female; Foreign Bodies; Humans; Hypertension, Pulmonary; Lung; Lung Diseases; Mercury; Methotrexate; Nitrofurantoin; Paraquat; Phenytoin; Pneumonia; Polymyxins; Radiation Injuries; Sulfonamides

1977
Clinically important interactions of nonsteroidal antiinflammatory drugs with other medications.
    The Journal of rheumatology. Supplement, 1988, Volume: 17

    Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Diuretics; Drug Interactions; Humans; Hypoglycemic Agents; Lithium; Methotrexate; Phenytoin; Probenecid; Salicylates; Triamterene

1988
Drug-induced lung disease.
    Chest, 1973, Volume: 63, Issue:3

    Topics: Anti-Bacterial Agents; Anticoagulants; Antihypertensive Agents; Bleomycin; Busulfan; Chlorpropamide; Cyclophosphamide; Hemorrhage; Heroin; Humans; Hydrochlorothiazide; Hypertension, Pulmonary; Inhalation; Leukemia, Lymphoid; Lipids; Lung; Lung Diseases; Methotrexate; Methysergide; Nitrofurantoin; Phenytoin; Pulmonary Edema

1973
Current concepts in therapy: drug-induced malabsorption--a review.
    Southern medical journal, 1973, Volume: 66, Issue:6

    Topics: Aminosalicylic Acids; Calcium Carbonate; Cholestyramine Resin; Clofibrate; Colchicine; Contraceptives, Oral; Diuretics; Ethanol; Humans; Intestinal Absorption; Malabsorption Syndromes; Mannitol; Methotrexate; Phenytoin

1973
Mechanisms of teratogenesis.
    Annual review of pharmacology and toxicology, 1984, Volume: 24

    Topics: Aminopterin; Androgens; Animals; Antithyroid Agents; Chromosome Aberrations; Coumarins; Diethylstilbestrol; Embryo, Mammalian; Ethanol; Female; Fetus; Humans; Methotrexate; Methylmercury Compounds; Mutagens; Nucleic Acids; Oxazoles; Phenytoin; Polychlorinated Biphenyls; Pregnancy; Progestins; Teratogens; Tetracycline; Thalidomide; Thyroid Hormones

1984
Drug-induced megaloblastic change.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim

1980

Other Studies

44 other study(ies) available for phenytoin and methotrexate

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effect of ethanol, diphenylhydantoin, methotrexate and low sodium ion concentration on jejunal surface pH and folic acid transfer in the rat [proceedings].
    Biochemical Society transactions, 1978, Volume: 6, Issue:1

    Topics: Animals; Biological Transport; Ethanol; Folic Acid; Hydrogen-Ion Concentration; Intestinal Mucosa; Jejunum; Methotrexate; Phenytoin; Rats; Sodium

1978
[Drug-induced pulmonary diseases: diagnostic, therapeutic and prognostic aspects. Apropos of 10 personal case reports].
    Revue des maladies respiratoires, 1992, Volume: 9, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Amiodarone; Ampicillin; Antihypertensive Agents; Benzothiadiazines; Bleomycin; Bronchoalveolar Lavage Fluid; Cyclophosphamide; Diuretics; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lung Diseases; Male; Methotrexate; Middle Aged; Phenytoin; Prognosis; Sodium Chloride Symporter Inhibitors; Sulindac; Thiamphenicol

1992
Effects of phenytoin sodium on doubling time, deoxyuridine suppression, 3H-methotrexate uptake and 57Co-cyanocobalamin uptake in HL60 cells.
    Clinical and laboratory haematology, 1990, Volume: 12, Issue:1

    Topics: Cell Division; Cell Survival; Cobalt Radioisotopes; Deoxyuridine; Folic Acid; Humans; Methotrexate; Phenytoin; Tritium; Tumor Cells, Cultured; Vitamin B 12

1990
Drug interactions with non steroidal anti-inflammatory drugs (NSAIDs).
    Scandinavian journal of rheumatology. Supplement, 1989, Volume: 83

    Topics: Administration, Oral; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Drug Interactions; Histamine H2 Antagonists; Humans; Hypoglycemic Agents; Lithium; Methotrexate; Phenytoin; Probenecid

1989
Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia.
    The Journal of pediatrics, 1988, Volume: 112, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Epilepsy; Humans; Leukemia, Lymphoid; Male; Mercaptopurine; Metabolic Clearance Rate; Methotrexate; Phenytoin; Prednisone; Vincristine

1988
The effects of ethanol methotrexate and diphenylhydantoin on [14C] leucine incorporation by human trophoblast cells cultured in vitro.
    British journal of obstetrics and gynaecology, 1987, Volume: 94, Issue:3

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Humans; In Vitro Techniques; Leucine; Methotrexate; Phenytoin; Protein Biosynthesis; Trophoblasts

1987
Transplacental chemical carcinogenesis in man.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:6

    Topics: Abnormalities, Drug-Induced; Aminopterin; Animals; Chloramphenicol; Diethylstilbestrol; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Maternal-Fetal Exchange; Methotrexate; Mice; Neoplasms; Neoplasms, Muscle Tissue; Phenytoin; Pregnancy; Uterine Cervical Neoplasms; Vaginal Neoplasms

1971
Drugs and folic acid absorption.
    Gastroenterology, 1972, Volume: 63, Issue:2

    Topics: Animals; Contraceptives, Oral; Folic Acid; Folic Acid Deficiency; Intestinal Absorption; Methotrexate; Phenytoin; Pyrimethamine; Sulfasalazine; Trimethoprim

1972
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
    Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24, Issue:4

    Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene

1973
Inhibition of high-affinity glial uptake of 14C-glutamate by folate.
    Nature, 1974, Aug-02, Volume: 250, Issue:465

    Topics: Animals; Carbon Radioisotopes; Epilepsy; Extracellular Space; Folic Acid; Ganglia, Spinal; Glutamates; Kinetics; Methotrexate; Neuroglia; Phenytoin; Pteridines; Rats

1974
Pulmonary complications of drug therapy.
    Radiology, 1970, Volume: 96, Issue:1

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Busulfan; Child; Drug-Related Side Effects and Adverse Reactions; Female; Hexamethonium Compounds; Humans; Hydrochlorothiazide; Lung Diseases; Male; Mecamylamine; Methotrexate; Methysergide; Middle Aged; Nitrofurantoin; Penicillins; Phenytoin; Pleural Effusion; Pneumonia, Pneumocystis; Procainamide; Pulmonary Edema; Pulmonary Fibrosis; Radiography; Sulfadimethoxine

1970
Studies of folate uptake by phytohaemagglutinin-stimulated lymphocytes.
    British journal of haematology, 1970, Volume: 19, Issue:2

    Topics: Adult; Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Biological Transport, Active; Carbon Isotopes; Cell Division; Culture Techniques; Dactinomycin; Folic Acid; Humans; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Methotrexate; Phenytoin; RNA; Stimulation, Chemical; Temperature; Tritium

1970
Uptake of tritiated folates by human bone marrow cells in vitro.
    British journal of haematology, 1971, Volume: 20, Issue:5

    Topics: Bone Marrow; Bone Marrow Cells; Chloromercuribenzoates; Folic Acid; Hematocrit; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Methotrexate; Phenytoin; Reticulocytes; Sulfhydryl Compounds; Tritium

1971
The absorption of pteroylglutamic (folic) acid in rats.
    British journal of haematology, 1969, Volume: 16, Issue:3

    Topics: Animals; Folic Acid; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Methotrexate; Phenytoin; Rats; Tritium; Xylose

1969
Evaluation of EMIT adapted to the (Cobas) Bio centrifugal analyzer.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1982, Volume: 20, Issue:10

    Topics: Centrifugation; Digoxin; Disopyramide; Humans; Immunoenzyme Techniques; Methotrexate; Phenytoin; Radioimmunoassay; Thyroxine

1982
Decreased phenytoin level during antineoplastic therapy: a case report.
    Epilepsia, 1983, Volume: 24, Issue:1

    Topics: Antineoplastic Agents; Brain Neoplasms; Carmustine; Drug Interactions; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Aged; Phenobarbital; Phenytoin; Seizures; Vinblastine

1983
Effects of anticonvulsants and methotrexate on calcium disposition.
    Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 315, Issue:1

    Topics: Animals; Anticonvulsants; Calcium; Calcium Radioisotopes; Folic Acid; Intestinal Absorption; Male; Methotrexate; Mice; Phenobarbital; Phenytoin

1980
Extramedullary blast transformation in the central nervous system in idiopathic myelofibrosis.
    American journal of hematology, 1981, Volume: 11, Issue:3

    Topics: Central Nervous System Diseases; Cerebrospinal Fluid; Dexamethasone; Humans; Male; Methotrexate; Middle Aged; Myeloproliferative Disorders; Phenytoin; Primary Myelofibrosis; Tomography, X-Ray Computed; X-Rays

1981
Intestinal folic acid absorption and the acid microclimate. The effects of compounds relevant to folate malabsorption.
    Pflugers Archiv : European journal of physiology, 1981, Volume: 392, Issue:1

    Topics: Animals; Ethanol; Folic Acid; Folic Acid Deficiency; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Jejunum; Leucine; Malabsorption Syndromes; Methotrexate; Phenytoin; Rats

1981
PELIOSIS HEPATIS. AN ANATOMIC STUDY WITH DEMONSTRATION OF TWO VARIETIES.
    Archives of pathology, 1964, Volume: 77

    Topics: Anatomy; Chlorambucil; Classification; Cyclophosphamide; Dactinomycin; Femoral Fractures; Geriatrics; Liver Diseases; Mediastinal Neoplasms; Methotrexate; Neoplasm Metastasis; Norethandrolone; Parkinsonian Disorders; Pathology; Peliosis Hepatis; Phenytoin; Prostheses and Implants; Psychosurgery; Teratoma; Testosterone; Wound Healing

1964
Posterior reversible encephalopathy syndrome and oral methotrexate.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:6

    Topics: Aged; Anticonvulsants; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Cell Count; Brain; Female; Humans; Magnetic Resonance Imaging; Methotrexate; Phenytoin; Posterior Leukoencephalopathy Syndrome; Tomography, X-Ray Computed; Treatment Outcome

2012
Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma.
    Toxicology letters, 2014, Nov-04, Volume: 230, Issue:3

    Topics: Animals; Atropine; Captopril; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Flutamide; Lamivudine; Liver; Male; Mannitol; Metabolomics; Methotrexate; Neomycin; Oxidative Stress; Phenytoin; Piperazines; Propylthiouracil; Rats; Rats, Wistar; Streptomycin; Triazoles; Valproic Acid; Vancomycin; Zidovudine

2014
Synthesis, molecular docking, ADMET evaluation and
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Methotrexate; Molecular Docking Simulation; Molecular Structure; Phenytoin; Rhabdomyosarcoma; Structure-Activity Relationship; Vero Cells

2023