phenytoin and methadone

phenytoin has been researched along with methadone in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's2 (7.41)18.2507
2000's1 (3.70)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lion, JR1
Chernoff, GF; Jones, KL1
Clouet, DH; O'Callaghan, JP; Williams, N1
Brocco, MJ; Killam, KF; Robinson, CA1
Gibson, TC1
Beckner, TF; Idsvoog, P1
Fong, GR1
Finelli, PF1
Hawker, CS; Saxon, AJ; Whittaker, S1
Cadden, JJ; Feigelson, EB1
Affrime, M; Reidenberg, MM1
McBay, AJ1
Reidenberg, MM1
Cimbura, G; Kofoed, J1
Ball, JC; Urbaitis, JC1
Benowitz, NL; Jaffery, NF; Kreek, MJ; Pond, SM; Tong, TG1
Haefeli, WE; Knoll, B; Ladewig, D; Stohler, R1
Madras, JL; Poujade, F; Saulnier, JL; Schlatter, J1
Bartold, PM; Hughes, FJ1
Oleynick, C; Prosperi-Porta, G1

Reviews

7 review(s) available for phenytoin and methadone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Conceptual issues in the use of drugs for the treatment of aggression in man.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adolescent; Adult; Aggression; Alcoholic Intoxication; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Butyrophenones; Cannabis; Chlordiazepoxide; Disease Models, Animal; Epilepsy; Gonadal Steroid Hormones; Humans; Hyperkinesis; Impulsive Behavior; Lithium; Male; Methadone; Paranoid Disorders; Phenothiazines; Phenytoin; Psychopharmacology; Psychosurgery; Schizophrenia; Thiothixene; Violence

1975
Drugs and chemicals associated with intrauterine growth deficiency.
    The Journal of reproductive medicine, 1978, Volume: 21, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Aminopterin; Animals; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Fetal Growth Retardation; Heroin Dependence; Humans; Infant, Low Birth Weight; Infant, Newborn; Methadone; Mice; Phenytoin; Pregnancy; Rats; Smoking

1978
The heart in myasthenia gravis.
    American heart journal, 1975, Volume: 90, Issue:3

    Topics: Arrhythmias, Cardiac; Cholinesterase Inhibitors; Drug Synergism; Electrocardiography; Heart; Humans; Lidocaine; Meperidine; Methadone; Morphine; Myasthenia Gravis; Myocarditis; Myocardium; Neuromuscular Junction; Phenytoin; Procaine; Quinidine; Vectorcardiography

1975
Toxicological findings in fatal poisonings.
    Clinical chemistry, 1973, Volume: 19, Issue:4

    Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordiazepoxide; Dextropropoxyphene; Diazepam; Ethchlorvynol; Glutethimide; Heroin; Humans; Meprobamate; Methadone; Methanol; Morphine; Orphenadrine; Paraldehyde; Pentazocine; Phenothiazines; Phenytoin; Poisoning; Quinine; Salicylates; Toxicology; Tranquilizing Agents

1973
Effect of disease states on plasma protein binding of drugs.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Blood Proteins; Blood Urea Nitrogen; Creatinine; Dapsone; Digitoxin; Drug Interactions; Humans; Hypoproteinemia; Liver Cirrhosis; Methadone; Pharmaceutical Preparations; Phenytoin; Protein Binding; Quinidine; Serum Albumin; Triamterene; Uremia

1974
Periodontal complications of prescription and recreational drugs.
    Periodontology 2000, 2018, Volume: 78, Issue:1

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Calcium Channel Blockers; Cannabis; Contraceptives, Oral; Cyclosporine; Diphosphonates; Gingiva; Gingival Overgrowth; Hallucinogens; Hormone Replacement Therapy; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Illicit Drugs; Immunosuppressive Agents; Inflammation; Methadone; Periodontal Diseases; Periodontal Index; Periodontium; Phenytoin; Platelet Aggregation Inhibitors; Tropanes

2018

Other Studies

20 other study(ies) available for phenytoin and methadone

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
The effect of opiates on endogenous phosphorylation of proteins in the synaptic plasma membranes of rat striatum.
    Progress in clinical and biological research, 1979, Volume: 27

    Topics: Animals; Corpus Striatum; Drug Tolerance; Illicit Drugs; Male; Methadone; Morphine; Naloxone; Narcotics; Nerve Tissue Proteins; Phenytoin; Phosphorylation; Protein Kinases; Rats; Synaptic Membranes

1979
Evaluation of narcotic and narcotic antagonist interactions in primates.
    Annals of the New York Academy of Sciences, 1976, Volume: 281

    Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration

1976
Drug use and distribution in a pain rehabilitation center.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:3

    Topics: Adult; Amitriptyline; Barbiturates; Chronic Disease; Diet; Female; Formularies, Hospital as Topic; Humans; Male; Methadone; Pain; Pharmaceutical Preparations; Phenytoin; Snake Venoms

1975
Letter: Drug use in a pain rehabilitation center.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:11

    Topics: Amitriptyline; Chronic Disease; Drug Combinations; Humans; Methadone; Pain; Phenytoin; Snake Venoms

1975
Letter: Phenytoin and methadone tolerance.
    The New England journal of medicine, 1976, Jan-22, Volume: 294, Issue:4

    Topics: Drug Tolerance; Humans; Male; Methadone; Middle Aged; Phenytoin

1976
Valproic acid, unlike other anticonvulsants, has no effect on methadone metabolism: two cases.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:6

    Topics: Adult; Drug Therapy, Combination; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Phenytoin; Seizures; Substance Withdrawal Syndrome; Valproic Acid

1989
Changing patterns of drug abuse in New York City.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders

1974
Influence of disease on binding of drugs to plasma proteins.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Proteins; Blood Urea Nitrogen; Carbon Radioisotopes; Creatinine; Dapsone; Desipramine; Dialysis; Fluoresceins; Heart Failure; Humans; Hypoproteinemia; Liver Cirrhosis; Male; Methadone; Pharmaceutical Preparations; Phenytoin; Protein Binding; Quinidine; Triamterene; Ultrafiltration; Uremia

1973
A review of some GLD-FID derivitization techniques found useful in forensic toxicology.
    Journal of chromatographic science, 1974, Volume: 12, Issue:5

    Topics: Acetylation; Amphetamine; Bromides; Chromatography, Gas; Forensic Medicine; Formaldehyde; Glycols; Humans; Methadone; Methylation; Morphine; Oxidation-Reduction; Phenytoin; Toxicology

1974
Absence of major medical complications among chronic opiate addicts.
    The British journal of addiction to alcohol and other drugs, 1970, Volume: 65, Issue:2

    Topics: Age Factors; Aged; Codeine; Heroin; Humans; Injections; Male; Methadone; Middle Aged; Morphine; Opium; Patient Readmission; Phenytoin; Substance-Related Disorders; Time Factors

1970
Phenytoin-induced methadone withdrawal.
    Annals of internal medicine, 1981, Volume: 94, Issue:3

    Topics: Adult; Drug Administration Schedule; Drug Interactions; Humans; Male; Methadone; Phenytoin; Pyrrolidines; Substance Withdrawal Syndrome

1981
Early recurrence of withdrawal symptoms under phenytoin and chronic alcohol use.
    Pharmacopsychiatry, 1997, Volume: 30, Issue:2

    Topics: Adult; Alcoholism; Epilepsy, Generalized; Humans; Male; Methadone; Opioid-Related Disorders; Phenytoin; Substance Withdrawal Syndrome

1997
[Drug interactions with methadone].
    Presse medicale (Paris, France : 1983), 1999, Sep-04, Volume: 28, Issue:25

    Topics: Anticonvulsants; Antitubercular Agents; Antiviral Agents; Drug Interactions; Drug Therapy; Humans; Methadone; Phenytoin; Psychotropic Drugs; Rifampin

1999
Diffuse Deep T-Wave Inversions Following a Generalized Seizure.
    The American journal of case reports, 2019, Oct-26, Volume: 20

    Topics: Adult; Delayed Diagnosis; Diagnosis, Differential; Electrocardiography; Female; Humans; Methadone; Phenytoin; Seizures; Takotsubo Cardiomyopathy

2019