phenytoin and mephenytoin

phenytoin has been researched along with mephenytoin in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (53.57)	18.7374
1990's	14 (25.00)	18.2507
2000's	7 (12.50)	29.6817
2010's	5 (8.93)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Iqbal, MT; Kwon, CH; Wurpel, JN	1
Cortes, S; Kohn, H; Liao, ZK; Watson, D	1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bohlen, N; Hertl, M	1
Roger, J; Tassinari, CA	1
Canonne, MA; Hue, G; Landriau, N; Maitrot, B; Rocher, A	1
Buchthal, A	1
Lawrence, RC; Lovering, EG; Watson, JR	1
Weisner, B; Zangemeister, WH	1
Burk, PG; Nathanson, G; Pollack, MA	1
Rosenmund, H; Wad, N	1
Danda, J; Hamáková, K; Kraus, Z; Nozicková, M	1
Latham, AN; Sweeney, GD	1
Fishman, L; Hanson, V; Singsen, BH	1
Friel, P; Troupin, AS	1
Wehrhahn, L; Wiegrebe, W	1
Schlunegger, UP; Wehrhahn, L; Wiegrebe, W	1
Ojemann, LM; Troupin, AS	1
Pezeshk, A; Pezeshk, V	1
Acuff-Smith, KD; Minck, DR; Vorhees, CV	1
Altieri, LP; Kirshner, M; Perel, JM; Pollock, BG; Reynolds, CF; Yeager, AL	1
Eadie, MJ	1
Birkett, DJ; Doecke, CJ; McManus, ME; Miners, JO; Pond, SM; Sansom, LN; Veronese, ME	1
Breimer, DD; Schellens, JH; van der Wart, JH	1
Branch, RA; Guengerich, FP; Hall, SD; Wilkinson, GR	1
Lee, HS; Tan, SF; Wong, PT	1
Fujioka, H; Kishi, M; Masuda, Y; Miyazaki, H; Tan, T; Yokoyama, Y	1
Burke, JT; Thénot, JP	1
György, I; Ilyés, I; Kirilina, S; Tornai, A	1
Eichelbaum, M	2
Maas, D; Schubothe, H; Weber, S	1
Roeda, D; Westera, G	1
Burnham, WM; King, GA; Livingston, KE	1
Desiderio, C; Fanali, S; Küpfer, A; Thormann, W	1
Brøsen, K; Dalhoff, K; Flachs, H; Loft, S; Poulsen, HE; Ranek, L; Wantzin, P	1
Desager, JP; Horsmans, Y; Kanyinda, JM	1
Bajpai, M; Levy, RH; Roskos, LK; Shen, DD	1
Inoue, K; Mimura, M; Nakamura, S; Oda, H; Ohmori, S; Shimada, T; Yamazaki, H	1
Boothe, DM	1
Chang, YT; Loew, GH; Payne, VA	1
Buchwald, AL	1
Goldstein, JA	1
Kalhorn, TF; Lakehal, F; Levy, RH; Wurden, CJ	1
KOREY, SR	1
RUSKIN, DB	1
Jones, JP; Kneller, MB; Rettie, AE; Rock, DA; Suzuki, H; Trager, WF	1
BERNHARDT, H	1
Fuhr, U; Jaehde, U; Jetter, A; Kasel, D; Kirchheiner, J; Klaassen, T; Tomalik-Scharte, D	1
Bialer, M	1

Reviews

8 review(s) available for phenytoin and mephenytoin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Pharmacotherapy of epilepsy. II]. Die Medizinische Welt, 1978, Jun-02, Volume: 29, Issue:22 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid	1978
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid	1991
Determination of antiepileptic drugs. Journal of chromatography, 1985, May-10, Volume: 340 Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid	1985
[Genetic polymorphism of oxidative drug metabolism. Therapeutic and toxicologic implications]. Der Internist, 1983, Volume: 24, Issue:3 Topics: Adrenergic beta-Antagonists; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Mephenytoin; Oxidation-Reduction; Perhexiline; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenotype; Phenytoin; Polymorphism, Genetic; Receptors, Drug; Sparteine	1983
[Clinical significance and pathogenesis of drug- or microbe-induced autoimmune hemolytic anemias]. Immunitat und Infektion, 1983, Volume: 11, Issue:1 Topics: Adult; Anemia, Hemolytic, Autoimmune; Bacterial Infections; Female; Humans; Ibuprofen; Infections; Long-Term Care; Male; Mephenytoin; Methyldopa; Methysergide; Middle Aged; Phenytoin; Pneumonia, Mycoplasma; Virus Diseases	1983
Anticonvulsant therapy in small animals. The Veterinary clinics of North America. Small animal practice, 1998, Volume: 28, Issue:2 Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid	1998
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. British journal of clinical pharmacology, 2001, Volume: 52, Issue:4 Topics: Alleles; Anti-Ulcer Agents; Anticonvulsants; Cytochrome P-450 Enzyme System; Humans; Mephenytoin; Omeprazole; Pharmaceutical Preparations; Phenytoin; Polymorphism, Genetic	2001

Other Studies

48 other study(ies) available for phenytoin and mephenytoin

Article	Year
Synthesis and anticonvulsant activity of 2-iminohydantoins. Journal of medicinal chemistry, 1991, Volume: 34, Issue:6 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Hydantoins; Male; Mice; Structure-Activity Relationship	1991
Effect of structural modification of the hydantoin ring on anticonvulsant activity. Journal of medicinal chemistry, 1985, Volume: 28, Issue:5 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Male; Mice; Motor Activity; Pentylenetetrazole; Postural Balance; Structure-Activity Relationship	1985
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship	2003
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
[Adverse effects of anti-epileptic drugs]. Deutsche medizinische Wochenschrift (1946), 1975, Sep-19, Volume: 100, Issue:38 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid	1975
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs. Advances in neurology, 1975, Volume: 11 Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid	1975
[Determination of phenobarbital, mephenytoin and diphenylhydantoin in the surveillance of anticonvulsant treatment]. Annales de biologie clinique, 1976, Volume: 34, Issue:2 Topics: Barbiturates; Child; Chromatography, Gas; Epilepsy; Ether; Humans; Hydantoins; Mephenytoin; Methylation; Phenobarbital; Phenytoin; Solvents; Temperature	1976
Simple GLC analysis of anticonvulsant drugs in commercial dosage forms. Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:7 Topics: Anticonvulsants; Chromatography, Gas; Glutethimide; Hydantoins; Mephenytoin; Phenytoin; Primidone; Succinimides	1978
[A progressive systemic sclerosis like disease due to anticonvulsive therapy? (author's transl)]. Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1977, Volume: 45, Issue:9 Topics: Adolescent; Adult; Anticonvulsants; Dermatomyositis; Female; Humans; Lupus Erythematosus, Systemic; Male; Mephenytoin; Phenytoin; Scleroderma, Systemic	1977
Mucocutaneous eruptions due to antiepileptic drug therapy in children. Annals of neurology, 1979, Volume: 5, Issue:3 Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome	1979
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography. Journal of chromatography, 1978, Jul-01, Volume: 146, Issue:1 Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone	1978
[Toxic epidermal necrolosys -- Lyell's syndrome in a patient protractedly treated by anti-epileptic agents]. Ceskoslovenska dermatologie, 1976, Volume: 51, Issue:6 Topics: Adult; Anticonvulsants; Barbiturates; Epilepsy; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Stevens-Johnson Syndrome	1976
Binding of anticonvulsant drugs to cytochrome P-450: correlation with evidence of induction of hepatic microsomal enzymes. Canadian journal of physiology and pharmacology, 1976, Volume: 54, Issue:6 Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Glucaric Acid; Hexobarbital; In Vitro Techniques; Kinetics; Male; Mephenytoin; Microsomes, Liver; Phenobarbital; Phenylbutyrates; Phenytoin; Rats; Receptors, Drug; Urea	1976
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants. Pediatrics, 1976, Volume: 57, Issue:4 Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide; Female; Humans; Infant; Lupus Erythematosus, Systemic; Male; Mephenytoin; Phenobarbital; Phenytoin; Seizures; Succinimides; Trimethadione	1976
Flash-heater ethylation of some antiepileptic drugs. Clinical chemistry, 1975, Volume: 21, Issue:6 Topics: Alkylation; Anticonvulsants; Evaluation Studies as Topic; Hot Temperature; Humans; Mephenytoin; Mephobarbital; Methylation; Phenobarbital; Phenytoin; Primidone; Saliva	1975
Anticonvulsant osteomalacia. Archives of internal medicine, 1975, Volume: 135, Issue:7 Topics: Adolescent; Anticonvulsants; Bone and Bones; Humans; Male; Mephenytoin; Minerals; Osteomalacia; Phenobarbital; Phenytoin; Seizures; Vitamin D	1975
[Polarographic determination of some phenylsubstituted anticonvulsants]. Arzneimittel-Forschung, 1975, Volume: 25, Issue:4 Topics: Anticonvulsants; Chromatography, Thin Layer; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Polarography; Primidone	1975
[Nitration products of some phenyl-substituted anticonvulsants]. Pharmaceutica acta Helvetiae, 1975, Volume: 50, Issue:9 Topics: Anticonvulsants; Mephenytoin; Nitrogen; Phenobarbital; Phenytoin; Primidone	1975
Paradoxical intoxication--a complication of anticonvulsant administration. Epilepsia, 1975, Volume: 16, Issue:5 Topics: Carbamazepine; Drug Therapy, Combination; Humans; Hydantoins; Mephenytoin; Phenytoin; Seizures	1975
Drug-metal interactions: spectroscopic studies of copper hydantoin complexes. Journal of inorganic biochemistry, 1991, Volume: 42, Issue:4 Topics: Copper; Crystallization; Electron Spin Resonance Spectroscopy; Hydantoins; Mephenytoin; Molecular Structure; Phenytoin; Pyridines; Spectrophotometry, Infrared	1991
Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats. Teratology, 1991, Volume: 43, Issue:4 Topics: Animals; Behavior, Animal; Ear, Inner; Female; Hydantoins; Male; Mephenytoin; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains; Teratogens	1991
S-mephenytoin 4-hydroxylation in older Americans. European journal of clinical pharmacology, 1991, Volume: 40, Issue:6 Topics: Aged; Aging; Aryl Hydrocarbon Hydroxylases; Black People; Chromatography, High Pressure Liquid; Creatinine; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Mephenytoin; Mixed Function Oxygenases; Phenytoin; United States; White People	1991
Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes. British journal of clinical pharmacology, 1991, Volume: 31, Issue:2 Topics: Binding, Competitive; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Phenytoin; Sulfaphenazole; Tolbutamide	1991
Relationship between mephenytoin oxidation polymorphism and phenytoin, methylphenytoin and phenobarbitone hydroxylation assessed in a phenotyped panel of healthy subjects. British journal of clinical pharmacology, 1990, Volume: 29, Issue:6 Topics: Adult; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Oxidation-Reduction; Phenobarbital; Phenotype; Phenytoin	1990
Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:1 Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Hydantoins; Isoenzymes; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenytoin; Polymorphism, Genetic; Stereoisomerism; Warfarin	1987
N-demethylation of methyl and dimethyl derivatives of phenytoin and their anticonvulsant activities in mice. Japanese journal of pharmacology, 1988, Volume: 48, Issue:4 Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Electroshock; gamma-Aminobutyric Acid; Hydantoins; Injections, Intraperitoneal; Male; Mephenytoin; Mice; Mice, Inbred Strains; Phenytoin; Radioligand Assay	1988
Biopharmaceutical studies on hydantoin derivatives. V. Pharmacokinetics and pharmacodynamics of 5,5-diphenylhydantoin and 1-benzenesulfonyl-5,5-diphenylhydantoin. Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:3 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anticonvulsants; Brain; Dinoprostone; Injections, Intravenous; Injections, Intraventricular; Liver; Male; Mephenytoin; Mice; Phenytoin; Prostaglandins E; Protein Binding; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1986
Influence of anticonvulsant drugs on thyroid hormones in epileptic children. Acta paediatrica Hungarica, 1985, Volume: 26, Issue:4 Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Humans; Mephenytoin; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine	1985
Polymorphic drug oxidation in humans. Federation proceedings, 1984, May-15, Volume: 43, Issue:8 Topics: Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Debrisoquin; Humans; Mephenytoin; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenytoin; Polymorphism, Genetic; Sparteine; Tolbutamide	1984
The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: hydantoins and barbiturates. The International journal of applied radiation and isotopes, 1981, Volume: 32, Issue:11 Topics: Anticonvulsants; Barbital; Barbiturates; Carbon Radioisotopes; Hydantoins; Isotope Labeling; Mephenytoin; Phenobarbital; Phenytoin	1981
Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs. Epilepsia, 1980, Volume: 21, Issue:5 Topics: Acetazolamide; Animals; Dose-Response Relationship, Drug; Ethosuximide; Evoked Potentials; Male; Mephenytoin; Phenobarbital; Phenytoin; Photic Stimulation; Rats; Seizures; Trimethadione	1980
Analysis of mephenytoin, 4-hydroxymephenytoin and 4-hydroxyphenytoin enantiomers in human urine by cyclodextrin micellar electrokinetic capillary chromatography: simple determination of a hydroxylation polymorphism in man. Electrophoresis, 1994, Volume: 15, Issue:1 Topics: Buffers; Capillary Action; Chromatography; Cyclodextrins; Humans; Hydroxylation; Kinetics; Mephenytoin; Micelles; Phenytoin; Stereoisomerism	1994
Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis. Scandinavian journal of gastroenterology, 1993, Volume: 28, Issue:8 Topics: Adult; Aged; Antipyrine; Chemical and Drug Induced Liver Injury; Complement C3; Female; Halothane; HLA Antigens; Humans; Male; Mephenytoin; Metronidazole; Middle Aged; Phenotype; Phenytoin; Polymorphism, Genetic; Sparteine	1993
Relationship between mephenytoin, phenytoin and tolbutamide hydroxylations in healthy African subjects. Pharmacology & toxicology, 1996, Volume: 78, Issue:2 Topics: Adult; Democratic Republic of the Congo; Female; Humans; Hydroxylation; Male; Mephenytoin; Phenytoin; Tolbutamide	1996
Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite. Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:12 Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Phenytoin; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases	1996
Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. Archives of toxicology, 1997, Volume: 71, Issue:6 Topics: Adrenergic beta-Antagonists; Aniline Compounds; Animals; Antineoplastic Agents; Benzphetamine; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Dogs; Erythromycin; Ethanolamines; Ethylmorphine; Guinea Pigs; Humans; Macaca fascicularis; Mephenytoin; Microsomes, Liver; Nifedipine; Oxazines; Oxidation-Reduction; Phenacetin; Phenytoin; Rats; Species Specificity	1997
Homology modeling and substrate binding study of human CYP2C18 and CYP2C19 enzymes. Proteins, 1999, Nov-01, Volume: 37, Issue:2 Topics: Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Mephenytoin; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Phenytoin; Progesterone; Protein Conformation; Sequence Homology, Amino Acid	1999
Mephenytoin overdose--phenytoin poisoning incognito? Case report and mephenytoin/phenytoin comparison. Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:7 Topics: Adult; Drug Overdose; Female; Humans; Mephenytoin; Molecular Structure; Phenytoin	2000
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19. Epilepsy research, 2002, Volume: 52, Issue:2 Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chlorophyll; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Mephenytoin; Microsomes; Mixed Function Oxygenases; Oxcarbazepine; Phenytoin; Recombinant Proteins	2002
Effect of dilantin and mesantoin on the giant axon of the squid. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1951, Volume: 76, Issue:2 Topics: Animals; Axons; Decapodiformes; Hydantoins; Mephenytoin; Phenytoin; Shellfish	1951
Comparative results in seizure control using phenobarbital, dilantin, and mesantoin. The American journal of psychiatry, 1950, Volume: 107, Issue:6 Topics: Barbital; Epilepsy; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Seizures	1950
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors. Archives of biochemistry and biophysics, 2004, Sep-01, Volume: 429, Issue:1 Topics: Aryl Hydrocarbon Hydroxylases; Barbiturates; Binding Sites; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Design; Enzyme Activation; Hydantoins; Mephenytoin; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Phenobarbital; Phenytoin; Protein Binding	2004
Fatal granulocytopenia following hydantoins, mesantoin and dilantin; report of a case. Journal of the Medical Association of the State of Alabama, 1950, Volume: 19, Issue:7 Topics: Agranulocytosis; Hydantoins; Mephenytoin; Phenytoin	1950
Assessment of urinary mephenytoin metrics to phenotype for CYP2C19 and CYP2B6 activity. European journal of clinical pharmacology, 2008, Volume: 64, Issue:4 Topics: Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Data Interpretation, Statistical; Humans; Male; Mass Spectrometry; Mephenytoin; Middle Aged; Oxidoreductases, N-Demethylating; Phenotype; Phenytoin	2008
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)? Epilepsia, 2012, Volume: 53 Suppl 8 Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid	2012