Compounds > phenytoin

phenytoin and levoleucovorin

phenytoin has been researched along with levoleucovorin in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (69.23)	18.7374
1990's	1 (7.69)	18.2507
2000's	3 (23.08)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
McElhatton, PR; Sullivan, FM	1
Saunders, J; Wickramasinghe, SN; Williams, G	1
Reynolds, EH	1
Spector, RG	2
Dresner, AJ; Fitzgerald, JE; Hentz, DL; Kurtz, SM; Petrere, JA; Schardein, JL	1
Jenkins, D; Spector, RG	1
Gallagher, BB; Glass, D; Mattson, RH; Reynolds, EH	1
Bertino, JR; Levitt, M; Nixon, PF; Pincus, JH	1
Cleary, JD; Tidwell, BH	1
Brodribb, TR; Gilbar, PJ	1
Boersma, HH; de Krom, MC; van Rijswijk, RE; Veldhorst-Janssen, NM	1
Ohdo, S; Ohtani, H; Sawada, Y; Tsujimoto, M; Yamasaki, D	1

Reviews

1 review(s) available for phenytoin and levoleucovorin

Article	Year
Anticonvulsants, folic acid, and epilepsy. Lancet (London, England), 1973, Jun-16, Volume: 1, Issue:7816 Topics: Anemia, Macrocytic; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; Epilepsies, Partial; Epilepsy; Folic Acid; Humans; Leucovorin; Mice; Phenobarbital; Phenytoin; Primidone; Rabbits; Rats; Seizures	1973

Trials

1 trial(s) available for phenytoin and levoleucovorin

Article	Year
Folate therapy in epilepsy. A controlled study. Archives of neurology, 1973, Volume: 29, Issue:2 Topics: Clinical Trials as Topic; Cognition; Epilepsy; Evaluation Studies as Topic; Folic Acid; Humans; Leucovorin; Personality; Phenobarbital; Phenytoin; Primidone; Psychological Tests	1973

Other Studies

11 other study(ies) available for phenytoin and levoleucovorin

Article	Year
Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice. Toxicology and applied pharmacology, 1975, Volume: 34, Issue:2 Topics: Animals; Cleft Palate; Drug Interactions; Female; Gestational Age; Leucovorin; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens	1975
Effects of anticonvulsant drugs on the synthesis of DNA and protein by human bone marrow cells in vitro. Scandinavian journal of haematology, 1976, Volume: 17, Issue:4 Topics: Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Humans; Leucine; Leucovorin; Phenobarbital; Phenytoin; Protein Biosynthesis; Thymidine	1976
The influence of anticonvulsant drugs on formyl tetrahydrofolic acid stimulation of rat brain respiration in vitro. Biochemical pharmacology, 1972, Dec-01, Volume: 21, Issue:23 Topics: Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; In Vitro Techniques; Leucovorin; Male; Microsomes; Norepinephrine; Oxygen Consumption; Phenobarbital; Phenytoin; Primidone; Rats; Scopolamine; Synaptosomes; Thiazines	1972
Influence of folic acid on excitable tissues. Nature: New biology, 1972, Dec-20, Volume: 240, Issue:103 Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Exploratory Behavior; Female; Folic Acid; Heart; Heart Rate; Ileum; In Vitro Techniques; Kidney; Leucovorin; Mice; Motor Activity; Muscle Contraction; Myocardium; Norepinephrine; Phenytoin; Pulse; Rats; Uterus	1972
The modifying effect of folinic acid on diphenylhydantoin-induced teratogenicity in mice. Toxicology and applied pharmacology, 1973, Volume: 24, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Fetal Death; Fetus; Leucovorin; Mice; Organ Size; Phenytoin; Pregnancy; Sex Factors; Time Factors	1973
The actions of folate and phenytoin on the rat heart in vivo and in vitro. Biochemical pharmacology, 1973, Jul-15, Volume: 22, Issue:14 Topics: Animals; Blood Pressure; Calcium Chloride; Folic Acid; Heart; Heart Rate; In Vitro Techniques; Leucovorin; Phenytoin; Rats; Time Factors	1973
Transport characteristics of folates in cerebrospinal fluid; a study utilizing doubly labeled 5-methyltetrahydrofolate and 5-formyltetrahydrofolate. The Journal of clinical investigation, 1971, Volume: 50, Issue:6 Topics: Anemia, Macrocytic; Animals; Biological Transport; Blood-Brain Barrier; Carbon Isotopes; Chromatography, Gel; Dogs; Female; Folic Acid; Kinetics; Leucovorin; Male; Phenytoin; Tritium	1971
Comment: leucovorin-phenytoin: a drug-drug interaction? The Annals of pharmacotherapy, 1995, Volume: 29, Issue:12 Topics: Anticonvulsants; Antitoxins; Drug Interactions; Humans; Leucovorin; Phenytoin	1995
Phenytoin and fluorouracil interaction. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:11 Topics: Aged; Anticonvulsants; Antidotes; Antimetabolites, Antineoplastic; Colonic Neoplasms; Drug Interactions; Fluorouracil; Humans; Leucovorin; Male; Phenytoin; Seizures	2001
Oral tegafur/folinic acid chemotherapy decreases phenytoin efficacy. British journal of cancer, 2004, Feb-09, Volume: 90, Issue:3 Topics: Administration, Oral; Anticonvulsants; Antimetabolites, Antineoplastic; Carcinoma; Drug Interactions; Epilepsy; Humans; Leucovorin; Male; Middle Aged; Phenytoin; Rectal Neoplasms; Tegafur	2004
Possible mechanisms for the pharmacokinetic interaction between phenytoin and folinate in rats. Therapeutic drug monitoring, 2007, Volume: 29, Issue:4 Topics: Analysis of Variance; Animals; Anticonvulsants; Drug Interactions; In Vitro Techniques; Leucovorin; Male; Metabolic Clearance Rate; Microsomes, Liver; Phenytoin; Protein Binding; Rats; Rats, Sprague-Dawley	2007