phenytoin has been researched along with leucine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Boquist, L | 1 |
| Saunders, J; Wickramasinghe, SN; Williams, G | 1 |
| MacKinney, AA; Vyas, R | 2 |
| Jones, GL; Woodbury, DM | 1 |
| Landon, MJ; Morgan, DM; Toothill, VJ | 1 |
| Iversen, LL; Minchin, MC | 1 |
| Cramer, JW; Whyatt, PL | 1 |
| Appel, SH; Autilio, L; Escueta, AV; Festoff, BW | 1 |
| MacKinney, AA; Vas, R | 1 |
| Marx, JV; Richert, DA; Ruegamer, WR; Westerfeld, WW | 1 |
| Freinkel, N; Knopp, RH; Scheinin, JC | 1 |
| Herbert, V; Momtazi, S | 1 |
| Stright, PL; Swaiman, KF | 1 |
| Beller, BM; Mongillo, S | 1 |
| Hamberger, A; Yanagihara, T | 2 |
| Colin, AA; Guttman, H; Hochberg, Z; Spindel, A | 1 |
| Kusek, JC | 1 |
| Blair, JA; Lucas, ML; Swanston-Flatt, SK | 1 |
| Chiba, K; Hosakawa, M; Kobayashi, K; Tainaka, H; Takanashi, K; Yasumori, T | 1 |
| Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA | 1 |
23 other study(ies) available for phenytoin and leucine
| Article | Year |
|---|---|
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Differences in the blood glucose response of mice to alloxan and alloxan-inhibiting compounds.
Topics: Acetazolamide; Alloxan; Animals; Bicarbonates; Blood Glucose; Deoxy Sugars; Diabetes Mellitus, Experimental; Eating; Hydroxymercuribenzoates; Lactates; Leucine; Mannoheptulose; Mice; Mice, Inbred C57BL; Phenytoin; Starvation; Tolbutamide | 1979 |
Effects of anticonvulsant drugs on the synthesis of DNA and protein by human bone marrow cells in vitro.
Topics: Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Humans; Leucine; Leucovorin; Phenobarbital; Phenytoin; Protein Biosynthesis; Thymidine | 1976 |
Effects of 5,5-diphenylhydantoin and related carbamates and hydroxylamines on nucleic acid and protein synthesis of proliferating human lymphocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Blood Proteins; Carbamates; DNA; Humans; Hydantoins; Hydroxyacetylaminofluorene; Hydroxylamines; In Vitro Techniques; Leucine; Lymphocytes; Phenytoin; Structure-Activity Relationship; Thymidine | 1975 |
Effects of diphenylhydantoin and phenobarbital on protein metabolism in the rat cerebral cortex.
Topics: Amino Acids; Animals; Cerebral Cortex; Kinetics; Leucine; Male; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats | 1976 |
The effects of ethanol methotrexate and diphenylhydantoin on [14C] leucine incorporation by human trophoblast cells cultured in vitro.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Humans; In Vitro Techniques; Leucine; Methotrexate; Phenytoin; Protein Biosynthesis; Trophoblasts | 1987 |
Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia.
Topics: Acetates; Alanine; Aminobutyrates; Animals; Calcium; Carbon Radioisotopes; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glycine; Hydroxylamines; Kinetics; L-Lactate Dehydrogenase; Lanthanum; Leucine; Magnesium; Neuroglia; Osmolar Concentration; Phenytoin; Potassium; Rats; Time Factors; Tritium | 1974 |
Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells.
Topics: Animals; Barbiturates; Cell Line; Clone Cells; DNA, Neoplasm; Leucine; Leukemia, Experimental; Mast-Cell Sarcoma; Mice; Mitosis; Neoplasm Proteins; Pentobarbital; Phenytoin; RNA, Neoplasm; Sarcoma, Experimental; Structure-Activity Relationship; Succinimides; Thymidine; Tritium; Uridine | 1973 |
Biochemical studies of synapses in vitro. 3. Ionic activation of protein synthesis.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Biological Transport, Active; Brain; Carbon Isotopes; Cyanides; Depression, Chemical; In Vitro Techniques; Leucine; Nerve Tissue Proteins; Ouabain; Oxygen Consumption; Phenytoin; Potassium; Rats; Sodium; Stimulation, Chemical; Synapses | 1969 |
The assay of diphenylhydantoin effects on growing human lymphocytes.
Topics: Adenosine Triphosphatases; Animals; Anticonvulsants; Carbon Isotopes; DNA; Folic Acid; Folic Acid Antagonists; Growth; Humans; Leucine; Leukocytes; Lymphocytes; Phenytoin; Phosphorus Isotopes; Potassium; Sodium; Thymidine; Tritium | 1973 |
Inhibition of the effects of thyroxine by 5,5-diphenyl-2-thiohydantoin.
Topics: Animals; Enzyme Induction; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Heart; Kidney; Leucine; Liver; Male; Mitochondria, Liver; Myocardium; Orotic Acid; Phenytoin; Protein Binding; Rats; Succinate Dehydrogenase; Sulfhydryl Compounds; Thyroxine | 1971 |
Diphenylhydantoin and an insulin-secreting islet adenoma.
Topics: Adenoma, Islet Cell; Adult; Blood Glucose; Epilepsy, Tonic-Clonic; Glucagon; Humans; Insulin; Insulin Secretion; Leucine; Male; Nitrogen; Pancreas; Phenytoin; Tolbutamide | 1972 |
Intestinal absorption using vibration-obtained individual small bowel epithelial cells of the rat: folate absorption.
Topics: Animals; Epithelial Cells; Epithelium; Folic Acid; Glucose; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Male; Methods; Phenytoin; Rats; Tritium; Vibration | 1973 |
The effects of anticonvulsants on in vitro protein synthesis in immature brain.
Topics: Animals; Brain; Carbon Isotopes; In Vitro Techniques; Leucine; Nerve Tissue Proteins; Phenobarbital; Phenytoin; Rats | 1973 |
Diphenylhydantoin-induced inhibition of nucleic acid synthesis in cultured human lymphocytes.
Topics: Blood Proteins; Cell Survival; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Humans; Kinetics; Lectins; Leucine; Lymphocyte Activation; Lymphocytes; Phenytoin; RNA; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Inhibition of incorporation of leucine into myocardial proteins of the rat by antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Antimetabolites; Heart; Heart Conduction System; Heart Rate; Leucine; Lidocaine; Muscle Proteins; Myocardium; Phenytoin; Procainamide; Propranolol; Quinidine; Rats; Tritium | 1969 |
Effect of diphenylhydantoin on protein metabolism in the central nervous system. Study of subcellular fractions.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Cerebral Cortex; Female; Heart; In Vitro Techniques; Leucine; Liver; Microsomes; Mitochondria; Myelin Sheath; Myocardium; Nerve Tissue Proteins; Phenytoin; Rats; Synaptic Vesicles; Tritium; Ultracentrifugation | 1971 |
Effect of diphenylhydantoin on protein metabolism in neuron and neuroglial fractions of central nervous tissue.
Topics: Animals; Cell Nucleus; Leucine; Microsomes; Nerve Endings; Nerve Tissue; Nerve Tissue Proteins; Neuroglia; Neurons; Phenytoin; Rats; Seizures; Tritium | 1971 |
Leucine-induced hypoglycemia in a family: effect of diphenylhydantoin, oxprenolol, and diazoxide.
Topics: Adult; Child; Child, Preschool; Diazoxide; Female; Genes, Dominant; Humans; Hypoglycemia; Infant; Leucine; Male; Oxprenolol; Pedigree; Phenytoin | 1984 |
The effects of phenytoin on in vitro protein synthesis in oral and non-oral tissues of the rat.
Topics: Animals; Cheek; Granuloma; In Vitro Techniques; Leucine; Male; Mouth Mucosa; Palate; Phenytoin; Protein Biosynthesis; Rats; Submandibular Gland | 1980 |
Intestinal folic acid absorption and the acid microclimate. The effects of compounds relevant to folate malabsorption.
Topics: Animals; Ethanol; Folic Acid; Folic Acid Deficiency; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Jejunum; Leucine; Malabsorption Syndromes; Methotrexate; Phenytoin; Rats | 1981 |
CYP2C9 Ile359 and Leu359 variants: enzyme kinetic study with seven substrates.
Topics: Aryl Hydrocarbon Hydroxylases; Base Sequence; Cytochrome c Group; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; DNA Primers; Humans; Isoleucine; Kinetics; Leucine; Microsomes; Mutagenesis, Site-Directed; Phenytoin; Recombinant Proteins; Schizosaccharomyces; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2000 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil | 2000 |