phenytoin has been researched along with lamotrigine in 218 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.92) | 18.7374 |
| 1990's | 46 (21.10) | 18.2507 |
| 2000's | 68 (31.19) | 29.6817 |
| 2010's | 80 (36.70) | 24.3611 |
| 2020's | 22 (10.09) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Carter, RB; Gharagozloo, P; Hogenkamp, DJ; Ilyin, VI; Nguyen, P; Robledo, S; Woodward, RM; Yang, J; Yao, J | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Kavya, R; Nageswari, Y; Ragavendran, JV; Sreevatsan, N; Sriram, D; Stables, J; Vanitha, K; Yogeeswari, P | 1 |
| Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M | 1 |
| Kotapati, S; Ragavendran, JV; Sriram, D; Stables, J; Yogeeswari, P | 1 |
| Verkman, AS; Yang, B; Zhang, H | 1 |
| Baheti, AR; Cocconcelli, G; Fantini, M; Ghiron, C; Kalmar, CL; Merrick, EC; Patel, MK; Rivara, M; Singh, N; Zuliani, V | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Baheti, AR; Cocconcelli, G; Fantini, M; Ghiron, C; Kalmar, CL; Katari, RS; Merrick, EC; Patel, MK; Rivara, M; Silva, C; Singh, N; Vacondio, F; Zuliani, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Marona, H; Pękala, E; Szneler, E; Walczak, M; Waszkielewicz, AM | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Kubová, H; Mares, P; Stanková, L | 1 |
| Binnie, CD; de Vries, J; Meijer, JW; Peck, AW; van Wieringen, A | 1 |
| Ashby, L; Cohen, AF; Crowley, D; Land, G; Miller, AA; Peck, AW | 1 |
| Buchanan, N; Sharpe, C | 1 |
| Debarnot, F; Mary, V; Pratt, J; Rataud, J; Stutzmann, JM | 1 |
| Duncan, JS; Patsalos, PN; Reutens, DC | 1 |
| al-Zubaidy, ZA; Chapman, AG; Meldrum, BS; Smith, SE | 1 |
| Jones, SR; Ramachandran, S; Underhill, S | 1 |
| Cooper, BR; Lang, DG; Wang, CM | 1 |
| Avanzini, G; Battino, D; Estienne, M | 1 |
| Aguglia, U; De Sarro, A; De Sarro, G; Nava, F | 1 |
| Kelly, KM; Macdonald, RL | 1 |
| Hyun, B; Jaing, Q; Treiman, DM; Walton, NY | 1 |
| Jürgens, U; May, TW; Rambeck, B | 1 |
| Kapetanovic, IM; Kupferberg, HJ; McNeilly, PJ; Strong, JM; Torchin, CD | 1 |
| Mercadé Cerdá, JM | 1 |
| Chapman, DP; Giles, WH | 1 |
| Gidal, BE; Lensmeyer, GL; Wiebe, DA | 1 |
| Appel, G; Chhiap, V; Grossman, ME; Jones, D; Resor, S | 1 |
| Vossler, DG; Wyler, AR | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| Heal, DJ; Martin, KF; Phillips, I; Thompson, KS | 1 |
| Curry, WJ; Kulling, DL | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Luer, MS; Winkler, SR | 1 |
| Simonart, T; Tugendhaft, P | 1 |
| Berlinghieri, MC; David, E; De Sarro, GB; Dominijanni, A; Elia, M; Gulletta, E; Musumeci, SA | 1 |
| Anderson, GD | 1 |
| Dutton, J; Higgins, G; Hughes, A; Roberts, NB | 1 |
| Kuroda, S; Morimoto, K; Otsuki, K; Sato, K; Yamada, N | 1 |
| Kamali, F; Webb, J | 1 |
| Kuo, CC | 1 |
| Chang, GY; Gilliam, F; Messenheimer, J; Nyberg, J; Risner, ME; Rudd, GD; Sackellares, JC; Vazquez, B | 1 |
| Hagan, RM; Higgins, GA; Kirkby, D; Southam, E | 1 |
| Donnelly, A; Potter, JM | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Marfia, GA; Pisani, A | 1 |
| Chen, C; Cox, E; Fiedler-Kelly, J; Grasela, TH; Risner, ME; Womble, GP | 1 |
| Böttiger, Y; Ståhle, L; Svensson, JO | 1 |
| Abbott, R; Dellaportas, CI; Findley, LJ; Gibberd, FB; Gross, M; Park, DM; Perkin, GD; Steiner, TJ | 1 |
| Benham, CD; Caeser, M; Evans, ML | 1 |
| Brodie, MJ | 1 |
| Fariello, RG; Maj, R; McArthur, RA; Pevarello, P; Salvati, P; Varasi, M | 1 |
| Albani, F; Baruzzi, AA; Contin, M; Riva, R | 1 |
| Carwile, ST; Husain, AM; Miller, PP; Radtke, RA | 1 |
| Bukhari, AA; McLean, MJ; Wamil, AW | 1 |
| Ebert, U; Löscher, W; Reissmüller, E | 1 |
| Brodie, MJ; Sills, GJ; Stephen, LJ | 1 |
| Harden, CL | 1 |
| Janowsky, DS | 1 |
| Malkiewicz, IM; Neuman, MG; Shear, NH | 1 |
| Jagoda, A; Yoon, Y | 1 |
| Cater, HL; Clare, JJ; Dale, TJ; John, VH; Peakman, TC; Xie, X | 1 |
| Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D | 1 |
| Beach, RL; D'Cruz, O; Tennison, M; Zaatreh, M | 1 |
| Brodie, MJ; Santangeli, S; Sills, GJ; Thompson, GG | 1 |
| Carvalho, D; Lanças, FM; Queiroz, ME; Silva, SM | 1 |
| Albani, F; Avoni, P; Baruzzi, A; Contin, M; Riva, R | 1 |
| Covington, EC | 1 |
| Anderson, GD; Gidal, BE; Gilliam, FG; Messenheimer, JA | 1 |
| Farber, NB; Heinkel, C; Jiang, XP; Nemmers, B | 1 |
| Backonja, MM | 1 |
| Rekling, JC | 1 |
| Bergin, AM; Connolly, M | 1 |
| Annovazzi, PO; Colombo, B; Comi, G | 1 |
| Harman, KE; Higgins, EM; Morris, SD | 1 |
| Berlowitz, D; Charbonneau, A; Cramer, J; Kazis, L; Knoefel, J; Mandell, A; Pugh, MJ | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Meussen-Elholm, ET; Olsen, CM; Røste, LS; Taubøll, E | 1 |
| Bajaj, K; Kumar, A | 1 |
| Cramer, JA; Hammer, AE; Kustra, RP | 1 |
| Hahn, JS; Hsu, D; Sandborg, C | 1 |
| Bromfield, EB; Drislane, FW; Farina, EL; Frye, CA; Herzog, AG; Kelly, KM; Pennell, PB; Schomer, DL | 1 |
| Yatham, LN | 1 |
| Papp, Z; Török, L | 1 |
| Buchan, S; Kerr, MP; Morgan, CL | 1 |
| Mishchenko, AL; Morozov, GV; Semenova, NV; Slastenko, OA | 1 |
| Bebin, EM; Burneo, JG; Miller, S; Prasad, A | 1 |
| Watson, CP | 1 |
| Ahmad, S; Fowler, LJ; Whitton, PS | 1 |
| Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P | 1 |
| Bodhankar, SL; Patil, KM | 1 |
| Alvey, CW; Bockbrader, HN; Brodie, MJ; Bron, NJ; Gibson, GL; Hounslow, NJ; Posvar, EL; Randinitis, EJ; Wesche, DL; Wilson, EA | 1 |
| Bromfield, EB; Drislane, FW; Dworetzky, BA; Farina, EL; Frye, CA; Herzog, AG; Pennell, PB; Schomer, DL | 2 |
| Bóné, B; Janszky, J | 1 |
| Baker, GA; Finnell, RH; Kalayjian, LA; Liporace, JD; Loring, DW; Mawer, G; Meador, KJ; Pennell, PB; Smith, JC; Wolff, MC | 1 |
| Donnelly, DF; Faustino, EV | 1 |
| Gale, K; Katz, I; Kim, J; Kondratyev, A | 1 |
| Alvestad, S; Brodtkorb, E; Lydersen, S | 1 |
| Baum, L; Cheng, AS; Kwan, P; Lau, KM; Man, CB; Ng, MH; Yu, E | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Grunze, H | 1 |
| Delima, SI; Golomb, MR; Walsh, LE | 1 |
| Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K | 1 |
| McMahon, DJ; Morrell, MJ; Pack, AM; Randall, A; Shane, E | 1 |
| Crooks, DP; Crozier, H; Doak, MW; Nixon, AC; Waring, WS | 1 |
| Bernášková, K; Mareš, P | 1 |
| Baker, GA; Browning, N; Clayton-Smith, J; Cohen, M; Combs-Cantrell, DT; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M | 1 |
| Hsieh, JY; Kuo, CC; Yang, YC | 1 |
| Wang, X; Xi, Z; Yan, Y; Zeng, K | 1 |
| Footitt, D; Mahon, D; Pournaras, DJ; Welbourn, R | 1 |
| Chen, CH; Chen, YT; Chu, CY; Chung, WH; Hsih, MS; Hui, RC; Hung, SI; Liu, ZS | 1 |
| Arif, H; Bazil, CW; Buchsbaum, R; Hirsch, LJ; Pierro, J; Resor, SR; Sims, J; Whalen, M | 1 |
| Akiyama, T; Otsubo, H | 1 |
| Kim, SE; Kim, SH; Kwon, OY; No, SK; Park, KM | 1 |
| Dahlin, MG; Ohman, I; Wide, K | 1 |
| Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F | 1 |
| Arumugamn, K; Bhat, K; Devarakonda, R; Gurumadhavrao, P; Jain, T; Mallayasamy, SR; Rajakannan, T | 1 |
| Espinosa, AG; García, VF; González, YR; Machado, RA; Melendrez, D; Rodríguez, YQ | 1 |
| Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P | 1 |
| George, AL; Kahlig, KM; Thompson, CH | 1 |
| Forcelli, PA; Gale, K; Kondratyev, A | 1 |
| Andrade, DM; Dalmau, J; Tai, P; Wennberg, R | 1 |
| Feuerstein, TJ; Freiman, TM; Kammerer, M; Rassner, MP | 1 |
| de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE | 1 |
| Alonso, ME; Dorado, P; Jung-Cook, H; Llerena, A; López, M; Machín, E; Monroy, N; Peñas-Lledó, E | 1 |
| Alexander, S; Bullman, J; Fleck, R; Messenheimer, J; Miller, J; Nicholls, A; Van Landingham, K; Vuong, A | 1 |
| Curtis, B; Erickson, SC; Harada, AS; Le, L; Ramsey, SD; Solow, BK; Stockl, KM; Zakharyan, A | 1 |
| McMahon, DJ; Morrell, MJ; Pack, AM; Shane, E | 1 |
| Aldana, BI; Chiu, LM; Guarneros, A; Sanchez-Tafolla, BM; Sitges, M | 1 |
| Phinney, KW; Tai, SS; Yeh, CY | 1 |
| Kotov, AS; Rudakova, IG | 1 |
| Hantson, P; Wittebole, X | 1 |
| Chung, WH; Dao, RL; Hung, SI; Lee, TJ; Lu, CW; Yang, CH; Yang, CY | 1 |
| Cavalleri, GL; Chaila, E; Delanty, N; Depondt, C; Heinzen, EL; Kasperavičiūtė, D; McCormack, M; O'Conner, GD; Pandolfo, M; Radtke, RA; Shianna, KV; Sisodiya, SM; Urban, TJ; Walley, N | 1 |
| Alkhotani, A; McLachlan, RS | 1 |
| Daniels, MA; George, AL; Kahlig, KM; Porter, JC; Thompson, CH | 1 |
| Baker, GA; Bromley, RL; Browning, N; Clayton-Smith, J; Cohen, MJ; Kalayjian, LA; Kanner, A; Liporace, JD; Loring, DW; Meador, KJ; Pennell, PB; Privitera, M | 1 |
| Alexander, JM; Wilson, KL | 1 |
| Alves, G; Falcão, A; Fortuna, A; Rocha, M; Serralheiro, A | 1 |
| Bednarski, J; Mosiewicz, J; Mróz, T; Ognik, J; Styk, A; Tutka, P; Łuszczki, J | 1 |
| Tanaka, S; Tanaka, T | 1 |
| Clare, JJ; Qiao, X; Sun, G; Wadman, WJ; Werkman, TR | 1 |
| Chiarelli, F; Cofini, M; Scaparrotta, A; Tiboni, GM; Verrotti, A | 1 |
| Huo, J; Li, X; Mei, S; Wang, J; Yu, K; Zhao, Z; Zhu, Y | 1 |
| Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM | 1 |
| Hong, SB; Joo, EY; Kim, HJ; Kim, TE; Lee, SY; Seo, DW | 1 |
| Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Francisco, J; Oliveira, P; Rodrigues, M; Rosado, L; Rosado, P | 1 |
| Abbasi, B; Asadi, M; Dadfarnia, S; Haji Shabani, AM | 1 |
| Babapour, V; Gavzan, H; Sardari, S; Sayyah, M | 1 |
| Doğan, Z; Kamışlı, Ö; Soysal, H | 1 |
| Abou-Khalil, BW | 1 |
| Fuller, HR; Garton, M; Wilson, EL | 1 |
| Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H | 1 |
| Bártfai, G; Devosa, I; Szok, D; Vanya, M | 1 |
| Chervoneva, I; Miller, R; Mintzer, S; Nei, M; Shah, K; Skidmore, C; Sperling, MR | 1 |
| Alves, G; Falcão, A; Ferreira, A; Rodrigues, M | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Hsieh, CY; Huang, CW; Lai, EC; Lin, SJ; Setoguchi, S; Su, CC; Yang, YK | 1 |
| Berezny, A; Cohen-Wolkowiez, M; Gonzalez, D; Greenberg, RG; Guptill, JT; Hill, KD; Hornik, CP; Jiang, W; Ku, LC; Melloni, C; Wu, H; Zheng, N | 1 |
| Fekete, S; Karesova, I; Kremlacek, J; Malakova, J; Palicka, V; Simko, J; Valis, M; Zimcikova, E; Zivna, H | 1 |
| French, CR; O'Brien, TJ; Taing, KD; Williams, DA | 1 |
| Castagna, CE; Miller, AB; Poolos, NP; Story, TJ; Williams, S | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Brozmanova, H; Grundmann, M; Kacirova, I; Koristkova, B | 1 |
| Bassolé, IHN; Gnankiné, O | 1 |
| Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C | 1 |
| Bermejo, PE; Gibbs, AA; Huberfeld, G; Kälviäinen, R; Shorvon, SD | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F | 1 |
| Bagary, M; Coleman, J; D'Amico, M; Denny, E; Dodds, J; Eldridge, S; Greenhill, L; Hard, K; Kelso, A; Khan, KS; Marlin, N; McCorry, D; Middleton, L; Moss, N; Newton, S; Pirie, A; Pullen, A; Rikunenko, R; Roberts, T; Rogozińska, E; Thangaratinam, S; Weckesser, A | 1 |
| Baker, GA; Bromley, RL; Clayton-Smith, J; Cohen, MJ; Conrad, T; Kalayjian, LA; Kanner, A; Liporace, JD; Loblein, H; Loring, DW; May, R; Meador, KJ; Pennell, PB; Privitera, M | 1 |
| Fedorova, IM; Tikhonov, DB | 1 |
| Ahmed, SI; Laghari, AA; Qadeer, N; Shamim, MS | 1 |
| Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ | 1 |
| Beran, RG; Kwok, A; Mamun, A; Sharobeam, A; Zandiehvakili, M | 1 |
| Behdani, M; Ghezelayagh, Z; Ghorbanian, MT; Habibi-Anbouhi, M; Hajizadeh-Saffar, E; Kardoost, M; Pooshang Bagheri, K | 1 |
| A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV | 1 |
| Bridgewater, B; Feng, S; McIntire, G; Strickland, EC | 1 |
| Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H | 1 |
| Ahn, KM; Chung, SJ; Oh, JH; Park, HW; Shim, JS | 1 |
| Afkhami Ardakani, S; Eslahi, A; Farrokhi, S; Jarahi, L; Kiafar, B; Mojarad, M; Mortezaee, R; Sabourirad, S; Shahrokhi, Y | 1 |
| Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME | 1 |
| Czuczwar, SJ; Łukawski, K | 1 |
| Demir, O; Kaplan, YC | 1 |
| Amagai, M; Fukasawa, T; Takahashi, H; Takahashi, K; Tanemura, N; Urushihara, H | 1 |
| Catalano, C; Gupta, K; Kamitaki, BK; Minacapelli, CD; Rustgi, V; Wachuku, C; Zhang, P | 1 |
| Hira, D; Kakumoto, M; Okano, T; Shimokawa, K; Ueshima, S | 1 |
| Linnér, L; Loikas, D; Sundström, A; von Euler, M; Wettermark, B | 1 |
| Afshar Mogaddam, MR; Farajzadeh, MA; Jouyban, A; Khosrowshahi, EM; Nemati, M; Tuzen, M | 1 |
| Barnhart, H; Björnsson, E; Bonkovsky, HL; Chalasani, N; Fontana, RJ; Gu, J; Hoofnagle, JH; Jacobsen, E; Kleiner, DE; Stine, JG | 1 |
| Fong, SL; Hariraj, V; Ho, JH; Lai, PSM; Lee, SC; Lim, KS; Ng, WL; Ramli, A; Wo, WK | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Agrawal, M; Dhurandhar, Y; Panda, SP | 1 |
| Barnett, A; Bock, T; Buss, EW; Engeland, B; Isbrandt, D; Kasemir, J; Leroy, F; Merseburg, A; Moroni, A; Porro, A; Santoro, B; Siegelbaum, SA; Stockebrand, M; Tröder, SE | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Du, Y; Gong, J; Lin, J; Wang, X; Xia, N; Xu, H; Xu, Q; Zheng, R; Zhu, Z | 1 |
| Adab, N; Bluett-Duncan, M; Bromley, R; Christensen, J; Clayton-Smith, J; Edwards, K; Greenhalgh, J; Hill, RA; Jackson, CF; Khanom, S; Marson, AG; McGinty, RN; Pulman, J; Tudur Smith, C | 1 |
| Amengual-Gual, M; Barcia Aguilar, C; Douglass, LM; Gaínza-Lein, M; Jonas, R; Romeu, A; Sánchez Fernández, I; Torres, A | 1 |
45 review(s) available for phenytoin and lamotrigine
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenytoin; Thiazines; Triazines; Vigabatrin | 1995 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
[Antiepileptic drugs: mechanism of action].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenytoin; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Triazines; Vigabatrin | 1996 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Recent advancements in epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Neurosurgery; Phenylcarbamates; Phenytoin; Pia Mater; Propylene Glycols; Temporal Lobe; Topiramate; Triazines; Vigabatrin | 1997 |
Newer antiepileptic drugs: gabapentin, lamotrigine, felbamate, topiramate and fosphenytoin.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug review: part 2.
Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Drug Interactions; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
New treatments of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Olanzapine; Phenytoin; Pirenzepine; Topiramate; Treatment Outcome; Triazines | 1999 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Diazepam; Drug Overdose; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Topiramate; Triazines; Valproic Acid | 2000 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
Use of anticonvulsants for treatment of neuropathic pain.
Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nervous System Diseases; Pain; Phenytoin; Triazines; Zonisamide | 2002 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines | 2003 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
Management issues of neuropathic trigeminal pain from a medical perspective.
Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2004 |
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].
Topics: Androgens; Anticonvulsants; Bromocriptine; Carbamazepine; Cognition; Enzyme Induction; Epilepsy; Gonadal Steroid Hormones; Humans; Lamotrigine; Liver; Male; Oxcarbazepine; Phenytoin; Sexual Dysfunctions, Psychological; Testosterone; Triazines; Valproic Acid | 2006 |
[Anticonvulsants in the treatment of bipolar disorder].
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2007 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
[Antiepileptic drugs in North America].
Topics: Anticonvulsants; Carbamazepine; Drug Approval; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Lorazepam; North America; Phenytoin; Piracetam; Topiramate; Triazines | 2010 |
Pharmacogenetics of the antiepileptic drugs phenytoin and lamotrigine.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Epilepsy; Genotype; Glucuronosyltransferase; Humans; Lamotrigine; Pharmacogenetics; Phenytoin; Polymorphism, Single Nucleotide; Triazines | 2011 |
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure.
Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Heavy Metal Poisoning; Humans; Lamotrigine; Liver Failure; Liver, Artificial; Metals, Heavy; Mushroom Poisoning; Phenytoin; Poisoning; Sorption Detoxification; Triazines | 2011 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
HLA-B*1502 increases the risk of phenytoin or lamotrigine induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: evidence from a meta-analysis of nine case-control studies.
Topics: Anticonvulsants; Case-Control Studies; Epilepsy; Genetic Predisposition to Disease; HLA-B15 Antigen; Humans; Lamotrigine; Phenytoin; Stevens-Johnson Syndrome; Triazines | 2015 |
Effects of phenytoin and lamotrigine treatment on serum BDNF levels in offsprings of epileptic rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Folic Acid; Lamotrigine; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Triazines | 2016 |
Antiepileptic Drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Seizures; Triazines | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Essential Oils as an Alternative to Pyrethroids' Resistance against Anopheles Species Complex Giles (Diptera: Culicidae).
Topics: Animals; Anopheles; Caco-2 Cells; Carbamazepine; Diptera; Hep G2 Cells; Humans; Lamotrigine; Levetiracetam; Oils, Volatile; Phenytoin; Piracetam; Pyrethrins; Triazines; Valproic Acid | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug and Narcotic Control; Drug-Related Side Effects and Adverse Reactions; Humans; Lamotrigine; Levetiracetam; Nitriles; Phenytoin; Pyridones; Seizures; Topiramate; Treatment Outcome | 2018 |
Choice of therapeutic anti-seizure medication in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; Lamotrigine; Levetiracetam; Neoplasm Grading; Phenytoin; Survival Rate; Topiramate; Valproic Acid; Zonisamide | 2019 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child.
Topics: Child; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Male; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Topiramate | 2023 |
16 trial(s) available for phenytoin and lamotrigine
| Article | Year |
|---|---|
Lamotrigine (BW430C), a potential anticonvulsant. Effects on the central nervous system in comparison with phenytoin and diazepam.
Topics: Adult; Anticonvulsants; Brain; Diazepam; Eye Movements; Humans; Hypnotics and Sedatives; Lamotrigine; Male; Movement; Phenytoin; Psychomotor Performance; Saliva; Triazines | 1985 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Analgesic effects of lamotrigine and phenytoin on cold-induced pain: a crossover placebo-controlled study in healthy volunteers.
Topics: Adult; Anticonvulsants; Blood Pressure; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Heart Rate; Humans; Lamotrigine; Male; Pain; Pain Measurement; Phenytoin; Psychomotor Performance; Reaction Time; Triazines | 1998 |
An active-control trial of lamotrigine monotherapy for partial seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Exanthema; Female; Humans; Hydrogen Peroxide; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 1998 |
Lamotrigine monotherapy in newly diagnosed untreated epilepsy: a double-blind comparison with phenytoin.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Double-Blind Method; Drug Administration Schedule; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Treatment Outcome; Triazines | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Topiramate in refractory epilepsy: a prospective observational study.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Prospective Studies; Topiramate; Treatment Outcome; Triazines | 2000 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin | 2000 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Time course of lamotrigine de-induction: impact of step-wise withdrawal of carbamazepine or phenytoin.
Topics: Adolescent; Adult; Aged; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Retrospective Studies; Substance Withdrawal Syndrome; Triazines | 2002 |
Quality of life improvement with conversion to lamotrigine monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Satisfaction; Phenytoin; Quality of Life; Sick Role; Substance Withdrawal Syndrome; Triazines | 2004 |
Differential effects of antiepileptic drugs on sexual function and hormones in men with epilepsy.
Topics: Adolescent; Adult; Age Factors; Aging; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Down-Regulation; Epilepsy; Estradiol; Gonadal Steroid Hormones; Humans; Lamotrigine; Luteinizing Hormone; Male; Middle Aged; Phenytoin; Sex Hormone-Binding Globulin; Sexual Dysfunction, Physiological; Testosterone; Triazines | 2005 |
In utero antiepileptic drug exposure: fetal death and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death; Humans; Lamotrigine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Triazines; Uterus; Valproic Acid | 2006 |
Effects of lamotrigine and phenytoin on the pharmacokinetics of atorvastatin in healthy volunteers.
Topics: Adolescent; Adult; Anticonvulsants; Atorvastatin; Cross-Over Studies; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lamotrigine; Male; Middle Aged; Phenytoin; Pyrroles; Triazines | 2011 |
Fetal antiepileptic drug exposure and cognitive outcomes at age 6 years (NEAD study): a prospective observational study.
Topics: Adult; Anticonvulsants; Child; Child Development; Child, Preschool; Cognition; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Observation; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Triazines | 2013 |
AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Monitoring; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Quality of Life; Seizures; United Kingdom | 2018 |
157 other study(ies) available for phenytoin and lamotrigine
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
Topics: Analgesics; Animals; Cell Line; Humans; Male; Pain; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Structure-Activity Relationship | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Semicarbazones; Structure-Activity Relationship; Touch | 2007 |
Inhibition of aquaporin 4 by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus | 2009 |
Newer GABA derivatives for the treatment of epilepsy including febrile seizures: a bioisosteric approach.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Epilepsy; Fever; gamma-Aminobutyric Acid; Mice; Molecular Structure; Rats; Rats, Wistar; Seizures, Febrile | 2008 |
Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides.
Topics: Animals; Anticonvulsants; Aquaporin 4; Biological Transport, Active; Cell Line; Mice; Molecular Structure; Neuroglia; Permeability; Rats; Structure-Activity Relationship; Sulfonamides; Thyroid Gland; Water | 2008 |
2,4(5)-Diarylimidazoles: synthesis and biological evaluation of a new class of sodium channel blockers against hNa(v)1.2.
Topics: Chemistry, Pharmaceutical; Drug Design; Humans; Imidazoles; Ion Channel Gating; Models, Chemical; Molecular Structure; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Protein Isoforms; Sodium; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship | 2008 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
2,4(5)-diarylimidazoles as inhibitors of hNaV1.2 sodium channels: pharmacological evaluation and structure-property relationships.
Topics: Cell Line; Electrophysiology; Humans; Imidazoles; Inhibitory Concentration 50; Sodium Channel Blockers; Sodium Channels; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Synthesis and anticonvulsant activity of trans- and cis-2-(2,6-dimethylphenoxy)-N-(2- or 4-hydroxycyclohexyl)acetamides and their amine analogs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Mice; Rats; Seizures | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
What to do when the first anticonvulsant does not work.
Topics: Aminocaproates; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1992 |
Anticonvulsant action of lamotrigine during ontogenesis in rats.
Topics: Aging; Animals; Anticonvulsants; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Lamotrigine; Male; Motor Activity; Pentylenetetrazole; Phenytoin; Rats; Rats, Wistar; Seizures; Triazines | 1992 |
Comparison of the effects of lamotrigine and phenytoin on the EEG power spectrum and cortical and brainstem-evoked responses of normal human volunteers.
Topics: Adult; Anticonvulsants; Brain; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Visual; Humans; Lamotrigine; Male; Phenytoin; Time Factors; Triazines | 1989 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Life Style; Male; Middle Aged; Phenytoin; Prognosis; Sleep Deprivation; Stress, Physiological; Time Factors; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 1995 |
Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents.
Topics: Animals; Anticonvulsants; Brain Ischemia; Carbamazepine; Cerebral Arteries; Electrophysiology; Electroshock; Imidazoles; Lamotrigine; Male; Mice; Phenytoin; Piperazines; Rats; Rats, Inbred F344; Seizures; Sodium Channels; Thiazoles; Triazines | 1994 |
Disabling tremor after lamotrigine with sodium valproate.
Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Phenytoin; Tremor; Triazines; Valproic Acid | 1993 |
Excitatory amino acid antagonists, lamotrigine and BW 1003C87 as anticonvulsants in the genetically epilepsy-prone rat.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Amino Acids, Cyclic; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Female; Lamotrigine; Male; Motor Activity; Phenytoin; Pyrimidines; Quinoxalines; Rats; Rats, Sprague-Dawley; Time Factors; Triazines | 1993 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Lamotrigine; Mice; Neuroblastoma; Phenytoin; Sodium Channels; Triazines; Tumor Cells, Cultured | 1993 |
Lamotrigine potentiates the antiseizure activity of some anticonvulsants in DBA/2 mice.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Diazepam; Drug Synergism; Female; Lamotrigine; Male; Mice; Mice, Inbred DBA; Phenytoin; Seizures; Triazines; Valproic Acid | 1996 |
Lamotrigine vs. phenytoin for treatment of status epilepticus: comparison in an experimental model.
Topics: Animals; Anticonvulsants; Brain; Chromatography, High Pressure Liquid; Cobalt; Convulsants; Electrodes, Implanted; Electroencephalography; Homocystine; Lamotrigine; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Status Epilepticus; Triazines | 1996 |
Stereoselective metabolism of a new anticonvulsant drug candidate, losigamone, by human liver microsomes.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Furans; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Lamotrigine; Microsomes, Liver; Mixed Function Oxygenases; Phenytoin; Recombinant Proteins; Stereoisomerism; Triazines | 1996 |
Optimized high-performance liquid chromatographic method for determination of lamotrigine in serum with concomitant determination of phenytoin, carbamazepine, and carbamazepine epoxide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenytoin; Triazines | 1997 |
Phenytoin-like hypersensitivity associated with lamotrigine.
Topics: Adult; Anticonvulsants; Drug Eruptions; Humans; Lamotrigine; Male; Phenytoin; Triazines | 1997 |
Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; Lamotrigine; Male; Neurons; Neuroprotective Agents; Phenytoin; Rats; Rats, Wistar; Riluzole; Sodium; Thiazoles; Triazines | 1997 |
Weak blockade of AMPA receptor-mediated depolarisations in the rat cortical wedge by phenytoin but not lamotrigine or carbamazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Lamotrigine; Male; Phenytoin; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Triazines | 1997 |
Phenytoin-like hypersensitivity associated with lamotrigine.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Exanthema; Humans; Lamotrigine; Phenytoin; Risk Factors; Syndrome; Triazines | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Effects of lamotrigine and conventional antiepileptic drugs on amygdala- and hippocampal-kindled seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 1998 |
A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels.
Topics: Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Carbamazepine; Kinetics; Lamotrigine; Neurons; Phenytoin; Rats; Rats, Long-Evans; Sodium Channel Blockers; Sodium Channels; Triazines | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Carbamazepine-10,11-epoxide in therapeutic drug monitoring.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Humans; Lamotrigine; Phenytoin; Sodium Channels; Triazines; Valproic Acid | 1998 |
An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Cerebral Cortex; Corpus Striatum; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Lamotrigine; Male; Membrane Potentials; Neurons; Phenytoin; Rats; Rats, Wistar; Triazines | 1999 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus.
Topics: Animals; Anticonvulsants; Benzamides; Benzopyrans; Carbamazepine; Cells, Cultured; Embryo, Mammalian; Hippocampus; Lamotrigine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Rats; Sodium Channel Blockers; Sodium Channels; Triazines | 1999 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Triazines | 1999 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Effects of topiramate on sodium-dependent action-potential firing by mouse spinal cord neurons in cell culture.
Topics: Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Fructose; Lamotrigine; Membrane Potentials; Mice; Neurons; Phenytoin; Sodium Channels; Spinal Cord; Topiramate; Triazines | 2000 |
The new antiepileptic drugs lamotrigine and felbamate are effective in phenytoin-resistant kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Epilepsies, Partial; Felbamate; Female; Kindling, Neurologic; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Wistar; Triazines | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Electrophysiological and pharmacological properties of the human brain type IIA Na+ channel expressed in a stable mammalian cell line.
Topics: Animals; Brain Chemistry; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Electric Conductivity; Electrophysiology; Gene Expression; Humans; Lamotrigine; Patch-Clamp Techniques; Phenytoin; Rats; Recombinant Proteins; Sodium Channels; Tetrodotoxin; Transfection; Triazines | 2001 |
Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction?
Topics: Anticonvulsants; Child, Preschool; Chorea; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Syndrome; Triazines | 2001 |
Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Lamotrigine; Male; Phenethylamines; Phenytoin; Rats; Rats, Wistar; Sodium; Sodium Channels; Synaptosomes; Tetrodotoxin; Triazines; Veratridine | 2002 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ion Channel Gating; Lamotrigine; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines; Valproic Acid | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Persistent anticonvulsant hypersensitivity syndrome responding to ciclosporin.
Topics: Adult; Anticonvulsants; Biopsy; Cyclosporine; Dermatologic Agents; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Interleukin-5; Lamotrigine; Phenytoin; Pruritus; Triazines | 2003 |
Potentially inappropriate antiepileptic drugs for elderly patients with epilepsy.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Phenytoin; Retrospective Studies; Triazines | 2004 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.
Topics: Anticonvulsants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estrogens; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Protein Binding; Receptors, Estrogen; Triazines; Valproic Acid | 2004 |
Synthesis and pharmacological evaluation of newer substituted benzoxazepine derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Benzazepines; Dose-Response Relationship, Drug; Electroshock; Lamotrigine; Magnetic Resonance Spectroscopy; Phenytoin; Seizures; Structure-Activity Relationship; Triazines | 2004 |
Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection.
Topics: Acute Disease; Anti-Inflammatory Agents; Anticonvulsants; Brain; Carbamazepine; Child, Preschool; Electroencephalography; Erythema Infectiosum; Female; Frontal Lobe; Humans; Lamotrigine; Magnetic Resonance Imaging; Ophthalmic Solutions; Parvovirus B19, Human; Phenytoin; Polymerase Chain Reaction; Prednisone; Seizures; Triazines; Uveitis; Video Recording | 2004 |
Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Estradiol; Humans; Lamotrigine; Luteinizing Hormone; Male; Middle Aged; Phenytoin; Sex Hormone-Binding Globulin; Sexual Behavior; Surveys and Questionnaires; Testosterone; Triazines | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey.
Topics: Aged; Anticonvulsants; Carbamazepine; Child, Preschool; Clinical Competence; Epilepsy; Family Practice; Female; Humans; Lamotrigine; Male; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Reflex; Evoked Potentials; Female; Frontal Lobe; Humans; Lamotrigine; Male; Myoclonus; Phenytoin; Photic Stimulation; Sunlight; Triazines; Valproic Acid; Video Recording | 2004 |
Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Hippocampus; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Serotonin; Time Factors; Triazines | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Triazines | 2005 |
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Pregabalin; Triazines; Valproic Acid | 2005 |
Lamotrigine and phenytoin, but not amiodarone, impair peripheral chemoreceptor responses to hypoxia.
Topics: Action Potentials; Amiodarone; Animals; Anticonvulsants; Chemoreceptor Cells; Female; Hypercapnia; Hypoxia; Lamotrigine; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Triazines; Vasodilator Agents | 2006 |
Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy.
Topics: Adolescent; Adult; Androgens; Androstanes; Anticonvulsants; Biological Availability; Carbamazepine; Dehydroepiandrosterone; Enzyme Induction; Epilepsies, Partial; Estradiol; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Sexual Dysfunctions, Psychological; Steroids; Testosterone; Triazines | 2006 |
Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Female; Lamotrigine; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Sex Factors; Thalamus; Triazines | 2007 |
Rash from antiepileptic drugs: influence by gender, age, and learning disability.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Comorbidity; Drug Eruptions; Epilepsy; Female; Humans; Hygiene; Incidence; Lamotrigine; Learning Disabilities; Male; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Triazines | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Female; Genetic Predisposition to Disease; HLA-B Antigens; HLA-B15 Antigen; Hong Kong; Humans; Lamotrigine; Male; Middle Aged; Pharmacogenetics; Phenytoin; Polymorphism, Genetic; Stevens-Johnson Syndrome; Triazines | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Simultaneous toxicities in a child on multiple anticonvulsants.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Liver; Liver Diseases; Lorazepam; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phenytoin; Status Epilepticus; Triazines; Valproic Acid | 2008 |
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium, Dietary; Carbamazepine; Collagen Type I; Epilepsy; Female; Femur; Humans; Lamotrigine; Life Style; Lumbar Vertebrae; Minerals; Parathyroid Hormone; Peptides; Phenytoin; Surveys and Questionnaires; Triazines; Valproic Acid; Vitamin D | 2008 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Psychotic Disorders; Retrospective Studies; Sex Distribution; Suicide, Attempted; Triazines; Valproic Acid; Young Adult | 2009 |
Similar effects of lamotrigine and phenytoin against cortical epileptic foci in immature rats.
Topics: Age Factors; Animals; Animals, Newborn; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Partial; Lamotrigine; Male; Motor Cortex; Phenytoin; Rats; Rats, Wistar; Time Factors; Triazines | 2010 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Intelligence; Intelligence Tests; Lamotrigine; Neuropsychological Tests; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Triazines; Valproic Acid | 2009 |
The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel.
Topics: Animals; Anticonvulsants; Binding Sites; Carbamazepine; Female; Ion Channel Gating; Lamotrigine; Models, Biological; Phenytoin; Point Mutation; Protein Structure, Tertiary; Rats; Sodium Channel Blockers; Sodium Channels; Triazines; Xenopus laevis | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Intelligence; Lamotrigine; Language Development Disorders; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Psychomotor Disorders; Topiramate; Triazines; Valproic Acid | 2009 |
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Drug Eruptions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Acceptance of Health Care; Phenytoin; Survival Analysis; Treatment Failure; Triazines; Valproic Acid; Young Adult | 2010 |
Reduced phenytoin levels in an epileptic patient following Roux-En-Y gastric bypass for obesity.
Topics: Anticonvulsants; Body Mass Index; Epilepsy; Gastric Bypass; Humans; Lamotrigine; Male; Middle Aged; Obesity, Morbid; Phenytoin; Postoperative Period; Triazines | 2011 |
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; HLA Antigens; HLA-B Antigens; HLA-B15 Antigen; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacogenetics; Phenytoin; Risk Factors; Stevens-Johnson Syndrome; Taiwan; Triazines; Young Adult | 2010 |
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines | 2010 |
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2010 |
Age and comedications influence levetiracetam pharmacokinetics in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Triazines; Valproic Acid | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
A sensitive and selective HPLC method for estimation of lamotrigine in human plasma and saliva: application to plasma-saliva correlation in epileptic patients.
Topics: Anticonvulsants; Calibration; Chromatography, High Pressure Liquid; Epilepsy; Humans; Indicators and Reagents; Lamotrigine; Phenytoin; Reference Standards; Reproducibility of Results; Saliva; Spectrophotometry, Ultraviolet; Triazines | 2010 |
Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Comorbidity; Depressive Disorder; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Prohibitins; Risk Factors; Suicidal Ideation; Suicide; Suicide, Attempted; Triazines; Young Adult | 2011 |
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Fever; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Risk Factors; Syndrome; Triazines; Young Adult | 2011 |
SCN1A splice variants exhibit divergent sensitivity to commonly used antiepileptic drugs.
Topics: Alternative Splicing; Anticonvulsants; Epilepsy; Humans; Lamotrigine; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Phenytoin; Protein Isoforms; Sodium Channels; Triazines | 2011 |
Early postnatal exposure of rats to lamotrigine, but not phenytoin, reduces seizure threshold in adulthood.
Topics: Aging; Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Female; Lamotrigine; Male; Phenytoin; Pregnancy; Rats; Rats, Sprague-Dawley; Triazines | 2011 |
Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Encephalitis; Female; Humans; Intracellular Signaling Peptides and Proteins; Lamotrigine; Levetiracetam; Middle Aged; Phenytoin; Piracetam; Proteins; Seizures; Triazines | 2011 |
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Clinical and pharmacy utilization outcomes with brand to generic antiepileptic switches in patients with epilepsy.
Topics: Anticonvulsants; Drug Substitution; Drugs, Generic; Emergency Service, Hospital; Epilepsy; Female; Hospitalization; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Proportional Hazards Models; Regression Analysis; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid | 2011 |
Normal vitamin D and low free estradiol levels in women on enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Bone Density; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Lamotrigine; Phenytoin; Triazines; Vitamin D | 2011 |
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids | 2011 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Topiramate; Triazines | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Severe cutaneous adverse reactions to antiepileptic drugs in Asians.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Exanthema; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Risk Factors; Severity of Illness Index; Stevens-Johnson Syndrome; Taiwan; Triazines | 2011 |
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Topics: Biomarkers, Pharmacological; Carbamazepine; Drug Hypersensitivity; Genome-Wide Association Study; HLA-A Antigens; Humans; Lamotrigine; Phenytoin; Polymorphism, Single Nucleotide; Triazines | 2012 |
Levetiracetam induced angioedema in a patient with previous anticonvulsant hypersensitivity reaction to phenytoin and lamotrigine.
Topics: Adult; Angioedema; Anticonvulsants; Exanthema; Female; Humans; Lamotrigine; Levetiracetam; Phenytoin; Piracetam; Triazines | 2012 |
Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Anticonvulsants; Cell Membrane; Epilepsies, Myoclonic; Gene Expression Regulation; HEK293 Cells; Humans; Lamotrigine; Mutation, Missense; NAV1.1 Voltage-Gated Sodium Channel; Phenytoin; Piperazines; Quinazolines; Sequence Deletion; Triazines | 2012 |
First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Lamotrigine; Limit of Detection; Linear Models; Phenobarbital; Phenytoin; Reproducibility of Results; Triazines | 2013 |
Cytisine inhibits the anticonvulsant activity of phenytoin and lamotrigine in mice.
Topics: Alkaloids; Animals; Anticonvulsants; Azocines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Injections, Intraperitoneal; Lamotrigine; Male; Mice; Phenytoin; Quinolizines; Seizures; Smoking Cessation; Triazines | 2013 |
Levetiracetam add-on therapy in Japanese patients with refractory partial epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepines; Clobazam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Complex Partial; Female; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2013 |
Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigine.
Topics: Anticonvulsants; Brain; Carbamazepine; HEK293 Cells; Humans; Lamotrigine; Phenytoin; Protein Subunits; Sodium Channels; Triazines; Voltage-Gated Sodium Channel Blockers | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Effect of comedication on lamotrigine clearance in Korean epilepsy patients.
Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 2015 |
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines | 2014 |
Simultaneous extraction and quantification of lamotrigine, phenobarbital, and phenytoin in human plasma and urine samples using solidified floating organic drop microextraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Lamotrigine; Limit of Detection; Liquid Phase Microextraction; Organic Chemicals; Osmolar Concentration; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Microextraction; Solvents; Temperature; Triazines | 2015 |
Synergistic effect of docosahexaenoic acid on anticonvulsant activity of valproic acid and lamotrigine in animal seizure models.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Kindling, Neurologic; Lamotrigine; Male; Mice; Pentylenetetrazole; Phenytoin; Rats; Rats, Wistar; Seizures; Triazines; Valproic Acid | 2015 |
Anti-epileptic drugs and bone loss: Phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells.
Topics: Animals; Anticonvulsants; Blotting, Western; Bone and Bones; Carbamazepine; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Fructose; Gene Expression Profiling; Lamotrigine; Levetiracetam; Microscopy, Confocal; Osteoblasts; Osteonectin; Phenytoin; Piracetam; Procollagen; Real-Time Polymerase Chain Reaction; Topiramate; Triazines; Valproic Acid | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein.
Topics: Anticonvulsants; Biomarkers; C-Reactive Protein; Carbamazepine; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Lipids; Male; Middle Aged; Phenytoin; Piracetam; Time Factors; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2016 |
A Rapid and Sensitive HPLC-DAD Assay to Quantify Lamotrigine, Phenytoin and Its Main Metabolite in Samples of Cultured HepaRG Cells.
Topics: Cell Line; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Lamotrigine; Limit of Detection; Phenytoin; Reproducibility of Results; Triazines | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Use of Therapeutic Drug Monitoring, Electronic Health Record Data, and Pharmacokinetic Modeling to Determine the Therapeutic Index of Phenytoin and Lamotrigine.
Topics: Adult; Aged; Anticonvulsants; Drug Monitoring; Drugs, Generic; Electronic Health Records; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Therapeutic Index; Triazines | 2016 |
The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats.
Topics: Absorptiometry, Photon; Animals; Anticonvulsants; Biomarkers; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Remodeling; Lamotrigine; Longitudinal Studies; Male; Phenytoin; Prospective Studies; Rats, Wistar; Triazines | 2016 |
Anti-Epileptic Drug Combination Efficacy in an In Vitro Seizure Model - Phenytoin and Valproate, Lamotrigine and Valproate.
Topics: Animals; Anticonvulsants; Drug Combinations; Drug Interactions; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Models, Theoretical; Phenytoin; Rats; Rats, Wistar; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Association between antiepileptic drug dose and long-term response in patients with refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistant Epilepsy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |
Lamotrigine Drug Interactions in Combination Therapy and the Influence of Therapeutic Drug Monitoring on Clinical Outcomes of Adult Patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Piracetam; Seizures; Topiramate; Triazines; Valproic Acid | 2017 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memory; Memory Disorders; Mothers; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Valproic Acid | 2019 |
Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Carbamazepine; Diptera; Lamotrigine; Lidocaine; Phenytoin; Synaptic Transmission; Voltage-Gated Sodium Channel Blockers | 2019 |
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsies, Partial; Epilepsy, Generalized; Female; Headache Disorders; Humans; Lamotrigine; Levetiracetam; Mental Disorders; Migraine Disorders; Mood Disorders; Oxcarbazepine; Phenytoin; Retrospective Studies; Risk; Teratogens; Topiramate; Valproic Acid; Young Adult | 2019 |
Management and attitudes toward patients with epilepsy in general practice: How far have we come in three decades?
Topics: Adult; Anticonvulsants; Attitude of Health Personnel; Australia; Carbamazepine; Clinical Competence; Electroencephalography; Epilepsy; Female; Follow-Up Studies; General Practitioners; Humans; Lamotrigine; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neurology; Phenytoin; Referral and Consultation; Surveys and Questionnaires; Valproic Acid | 2019 |
Genotoxicity assessment of antiepileptic drugs (AEDs) in human embryonic stem cells.
Topics: Anticonvulsants; Carbamazepine; DNA Damage; Epilepsy; Female; Human Embryonic Stem Cells; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy | 2019 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid | 2020 |
A Rapid LC-MS-MS Method for the Quantitation of Antiepileptic Drugs in Urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Drug Monitoring; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Tandem Mass Spectrometry; Topiramate | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid | 2020 |
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity Syndrome; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Republic of Korea; Severity of Illness Index; Stevens-Johnson Syndrome; Topiramate; Young Adult; Zonisamide | 2021 |
Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population.
Topics: Adult; Alleles; Anticonvulsants; Case-Control Studies; Female; HLA-B15 Antigen; Humans; Iran; Lamotrigine; Male; Middle Aged; Phenytoin; Predictive Value of Tests; Risk Factors; Stevens-Johnson Syndrome; Young Adult | 2021 |
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide | 2021 |
Developing precision treatments for epilepsy using patient and animal models.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Humans; Lamotrigine; Phenytoin | 2021 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; Female; Humans; Incidence; Japan; Lamotrigine; Levetiracetam; Logistic Models; Male; Middle Aged; Odds Ratio; Phenytoin; Risk Factors; Stevens-Johnson Syndrome | 2021 |
Drug-induced liver injury associated with antiseizure medications from the FDA Adverse Event Reporting System (FAERS).
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Humans; Lamotrigine; Levetiracetam; Phenytoin; United States | 2021 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Humans; Lamotrigine; NAV1.1 Voltage-Gated Sodium Channel; Neuroblastoma; Neuronal Outgrowth; Neurons; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2021 |
Post-stroke epilepsy and antiepileptic drug use in men and women.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Medication Adherence; Middle Aged; Phenytoin; Stroke; Sweden; Valproic Acid | 2021 |
pH-induced homogeneous liquid-liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Lamotrigine; Liquid Phase Microextraction; Milk, Human; Phenobarbital; Phenytoin; Solvents | 2021 |
Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dyphylline; Gabapentin; Humans; Lamotrigine; Middle Aged; Phenytoin; Prospective Studies; Seizures; United States | 2022 |
Incidence of Antiseizure Medication-Induced Severe Cutaneous Adverse Reactions in Malaysia.
Topics: Anticonvulsants; Drug Eruptions; Epilepsy; HLA Antigens; Humans; Incidence; Lamotrigine; Malaysia; Phenytoin; Retrospective Studies | 2022 |
Seizures, behavioral deficits, and adverse drug responses in two new genetic mouse models of
Topics: Animals; Anticonvulsants; Brain Diseases; Child; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Lamotrigine; Ligand-Gated Ion Channels; Mice; Phenytoin; Potassium Channels; Seizures | 2022 |
External validation of the AntiEpileptic Drug Monitoring in PREgnancy (EMPiRE) model for predicting seizures in pregnant women with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy; Pregnant Women; Prospective Studies | 2023 |
Evolution of antiseizure medication use and cost in the United States of America 2006-2021.
Topics: Adult; Anticonvulsants; Child; Drugs, Generic; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Retrospective Studies | 2023 |