phenytoin has been researched along with lacosamide in 43 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (2.33) | 18.2507 |
2000's | 3 (6.98) | 29.6817 |
2010's | 27 (62.79) | 24.3611 |
2020's | 12 (27.91) | 2.80 |
Authors | Studies |
---|---|
Choi, D; Kohn, H; Stables, JP | 1 |
Kohn, H; LeTiran, A; Stables, JP | 1 |
Kohn, H; Morieux, P; Stables, JP | 1 |
Cotten, SW; Eyers, C; Gaskell, SJ; Kohn, H; Liu, R; Morieux, P; Park, KD; Reamtong, O; Salomé, C; Stables, JP | 1 |
DeMarco, E; Kohn, H; Morieux, P; Park, KD; Salomé, C; Salomé-Grosjean, E; Stables, JP; Swendiman, R | 1 |
Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP | 1 |
Kohn, H; Morieux, P; Park, KD; Salomé, C; Stables, JP | 1 |
De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Valade, A | 1 |
De Ryck, M; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP; Valade, A | 1 |
De Ryck, M; Kaminski, R; King, AM; Kohn, H; Stables, JP; Valade, A | 1 |
Chodkowski, A; Dawidowski, M; Herold, F; Kleps, J; Szulczyk, P; Wilczek, M | 1 |
Baruah, PK; De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Provins, L; Salomé, C | 1 |
Dustrude, ET; Khanna, R; Kohn, H; Lee, H; Park, KD; Wilson, SM; Yang, XF | 1 |
Chońska, J; Dawidowski, M; Mika, W; Turło, J | 1 |
Cummins, TR; Dustrude, ET; Khanna, R; Kohn, H; Torregrosa, R; Yang, XF | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM | 1 |
LaRoche, SM; Shivdat-Nanhoe, R | 1 |
Berning, S; Kellinghaus, C; Stögbauer, F | 1 |
Husain, AM | 2 |
Duncan, JS; Markoula, S; Patsalos, PN; Ratnaraj, N; Sander, JW; Teotonio, R | 1 |
Kagiava, A; Karlovasitou, A; Kimiskidis, VK; Kosmidis, EK; Krikonis, K; Spilioti, M; Zafeiridou, G | 1 |
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
Brawanski, A; Höhne, J; Lange, M; Ott, C; Schebesch, KM | 1 |
Tikhonov, DB; Zhorov, BS | 1 |
Redecker, J; Rösche, J; Wittstock, M | 1 |
Bergqvist, AC; Božović, IB; DeBrosse, SD; Goldberg, EM; Helbig, I; Helbig, KL; Maver, A; Medne, L; Peterlin, B; Wallis, K; Zaman, T; Zhang, X | 1 |
Bhapkar, M; Dombrowski, KE; Gallentine, WB; Gerard, EE; Gupta, PK; Hahn, CD; Halford, JJ; Herman, ST; Hirsch, LJ; Husain, AM; Jones, JM; Kolls, BJ; LaRoche, SM; Lee, JW; Lokhnygina, Y; Minazad, Y; Palade, A; Sinha, SR; Swisher, CB; Westover, MB | 1 |
Abdulhamid, M; Barletta, JF; Dzandu, JK; Hall, ST; Kwon, SJ; Mangram, AJ; Zach, V | 1 |
Gaínza-Lein, M; Lamb, N; Loddenkemper, T; Sánchez Fernández, I | 1 |
Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H | 1 |
Araki, Y; Fukushima, Y; Imai, K; Kagawa, Y; Takahashi, Y; Terada, K; Yamamoto, Y | 1 |
Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME | 1 |
Dawman, L; Panda, P; Panda, PK; Sharawat, IK | 1 |
Bagdure, DN; Gopalakrishnan, M; Kalaria, SN; Kishk, OA | 1 |
Al Omari, O; Jani, C; McCannon, J; Patel, D; Perrino, C; Rupal, A; Singh, H; Walker, A | 1 |
Campoy, S; Huerta-Villanueva, M; Muñoz-Vendrell, A; Sala-Padró, J; Teixidor, S | 1 |
Armahizer, M; Badjatia, N; Gobburu, JV; Gopalakrishnan, M; Kalaria, SN; McCarthy, P | 1 |
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V | 1 |
Anzellotti, F; Bernardo, D; Calabresi, P; Consoli, S; Della Marca, G; Dono, F; Paci, L; Ricciardi, L; Rollo, E; Romozzi, M; Sensi, SL; Servidei, S; Vollono, C | 1 |
Czabanka, M; Kieslich, M; Merker, M; Purwien, L; Ronellenfitsch, MW; Rosenow, F; Schubert-Bast, S; Strzelczyk, A; Willems, LM | 1 |
8 review(s) available for phenytoin and lacosamide
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Lacosamide in status epilepticus: Update on the TRENdS study.
Topics: Acetamides; Anticonvulsants; Critical Illness; Humans; Lacosamide; Phenytoin; Recurrence; Seizures; Status Epilepticus | 2015 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Decision Support Techniques; Humans; Lacosamide; Levetiracetam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Failure; Valproic Acid | 2019 |
Efficacy of lacosamide and phenytoin in status epilepticus: A systematic review.
Topics: Anticonvulsants; Humans; Lacosamide; Phenytoin; Seizures; Status Epilepticus; Treatment Outcome | 2021 |
Intravenous lacosamide and phenytoin for the treatment of acute exacerbations of trigeminal neuralgia: A retrospective analysis of 144 cases.
Topics: Female; Humans; Lacosamide; Male; Middle Aged; Pain; Phenytoin; Retrospective Studies; Treatment Outcome; Trigeminal Neuralgia | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
[Paediatric status epilepticus].
Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid | 2022 |
1 trial(s) available for phenytoin and lacosamide
Article | Year |
---|---|
Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Waves; Cross-Over Studies; Electroencephalography; Epilepsy, Generalized; Female; Glasgow Coma Scale; Humans; Lacosamide; Male; Middle Aged; Phenytoin; Prospective Studies; Single-Blind Method; Treatment Outcome | 2018 |
34 other study(ies) available for phenytoin and lacosamide
Article | Year |
---|---|
Synthesis and anticonvulsant activities of N-Benzyl-2-acetamidopropionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Benzylamines; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Design and evaluation of affinity labels of functionalized amino acid anticonvulsants.
Topics: Affinity Labels; Amino Acids; Animals; Anticonvulsants; Electroshock; Isothiocyanates; Mice; Radioligand Assay; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2002 |
Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.
Topics: Acetamides; Animals; Anticonvulsants; Binding Sites; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship | 2008 |
Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.
Topics: Acetamides; Animals; Anticonvulsants; Brain; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Lacosamide; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Proteome; Seizures; Serine; Stereoisomerism; Structure-Activity Relationship | 2009 |
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides.
Topics: Acetamides; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Hippocampus; Kindling, Neurologic; Male; Mice; Molecular Structure; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Serine; Structure-Activity Relationship | 2010 |
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, Preclinical; Lacosamide; Mice; Pain; Rats; Seizures; Structure-Activity Relationship; Treatment Outcome | 2010 |
The structure-activity relationship of the 3-oxy site in the anticonvulsant (R)-N-benzyl 2-acetamido-3-methoxypropionamide.
Topics: Acetamides; Animals; Anticonvulsants; Electroshock; Hydrophobic and Hydrophilic Interactions; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2010 |
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Convulsants; Electroshock; Formaldehyde; Male; Mice; Neuralgia; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain
Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Butyrates; Male; Mice; Neuralgia; Pain Measurement; Propionates; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2011 |
Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.
Topics: Aminobutyrates; Animals; Anticonvulsants; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Solubility; Stereoisomerism; Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 1: perhydropyrrole[1,2-a]pyrazines.
Topics: Animals; Anticonvulsants; Diketopiperazines; Electroshock; Epilepsy; Humans; Male; Mice; Models, Molecular; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Sodium Channel Blockers; Sodium Channels | 2011 |
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides.
Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuralgia; Seizures; Structure-Activity Relationship | 2012 |
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents.
Topics: Ammonium Compounds; Animals; Anticonvulsants; Biphenyl Compounds; Male; Methylamines; Mice; Rats; Rats, Sprague-Dawley; Sodium Channels | 2013 |
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2014 |
Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
Topics: Acetamides; Administration, Oral; Amides; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electroshock; HEK293 Cells; Humans; Injections, Intraperitoneal; Male; Mice; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels | 2015 |
Design, synthesis and anticonvulsant-analgesic activity of new
Topics: | 2017 |
Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus.
Topics: Acetamides; Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Brain Diseases; Confusion; Diffusion Magnetic Resonance Imaging; Electroencephalography; Female; Humans; Lacosamide; Lorazepam; Middle Aged; Neurologic Examination; Paresis; Patient Compliance; Phenytoin; Seizures; Status Epilepticus; Tomography, X-Ray Computed; Valproic Acid | 2011 |
Intravenous lacosamide or phenytoin for treatment of refractory status epilepticus.
Topics: Acetamides; Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Female; Humans; Lacosamide; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retreatment; Retrospective Studies; Status Epilepticus; Treatment Outcome; Young Adult | 2014 |
Treatment of Recurrent Electrographic Nonconvulsive Seizures (TRENdS) study.
Topics: Acetamides; Anticonvulsants; Electroencephalography; Humans; Lacosamide; Monitoring, Physiologic; Phenytoin; Retrospective Studies; Secondary Prevention; Status Epilepticus; Treatment Outcome | 2013 |
Lacosamide serum concentrations in adult patients with epilepsy: the influence of gender, age, dose, and concomitant antiepileptic drugs.
Topics: Acetamides; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 2014 |
Differential effects of lacosamide, phenytoin and topiramate on peripheral nerve excitability: An ex vivo electrophysiological study.
Topics: Acetamides; Action Potentials; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; Fructose; In Vitro Techniques; Lacosamide; Male; Phenytoin; Rats; Sciatic Nerve; Topiramate | 2016 |
The risk of hypotension and seizures in patients receiving prophylactic anti-epileptic drugs for supratentorial craniotomy.
Topics: Acetamides; Adult; Anticonvulsants; Blood Pressure; Craniotomy; Female; Humans; Hypotension; Lacosamide; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Pre-Exposure Prophylaxis; Retrospective Studies; Seizures; Supratentorial Neoplasms | 2018 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |
The efficacy of different kinds of intravenously applied antiepileptic drugs in the treatment of status epilepticus. How can it be determined?
Topics: Acetamides; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Anticonvulsants; Female; Health Behavior; Humans; Lacosamide; Levetiracetam; Male; Middle Aged; Phenytoin; Piracetam; Retrospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid | 2017 |
Mutations in SCN3A cause early infantile epileptic encephalopathy.
Topics: Adolescent; Adult; Analysis of Variance; Cell Line, Transformed; Child, Preschool; Cohort Studies; Electric Stimulation; Female; Humans; Lacosamide; Magnetic Resonance Imaging; Male; Membrane Potentials; Models, Molecular; Mutation; NAV1.3 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenytoin; Sodium Channels; Spasms, Infantile; Transfection; Voltage-Gated Sodium Channel Blockers | 2018 |
Lacosamide versus phenytoin for the prevention of early post traumatic seizures.
Topics: Adult; Aged; Anticonvulsants; Brain Injuries, Traumatic; Drug-Related Side Effects and Adverse Reactions; Epilepsy, Post-Traumatic; Female; Humans; Incidence; Lacosamide; Male; Middle Aged; Phenytoin; Retrospective Studies | 2019 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid | 2020 |
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers | 2020 |
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide | 2021 |
Evaluation of an
Topics: Albumins; Anticonvulsants; Extracorporeal Membrane Oxygenation; Humans; Infant, Newborn; Lacosamide; Levetiracetam; Oxygenators, Membrane; Phenytoin; Saline Solution | 2022 |
Longstanding Phenytoin Use as a Cause of Progressive Dyspnea.
Topics: Biopsy; COVID-19; Diagnosis, Differential; Drug Substitution; Dyspnea; Humans; Lacosamide; Lung; Lung Diseases, Interstitial; Male; Middle Aged; Phenytoin; SARS-CoV-2; Seizures; Tomography, X-Ray Computed; Treatment Outcome; Voltage-Gated Sodium Channel Blockers | 2022 |
Development and Use of an Ex-Vivo In-Vivo Correlation to Predict Antiepileptic Drug Clearance in Patients Undergoing Continuous Renal Replacement Therapy.
Topics: Albumins; Anticonvulsants; Continuous Renal Replacement Therapy; Critical Illness; Drug Elimination Routes; Humans; Lacosamide; Levetiracetam; Phenytoin | 2022 |
Treatment of benzodiazepine-refractory status epilepticus: A retrospective, cohort study.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Cohort Studies; Female; Humans; Lacosamide; Levetiracetam; Male; Phenytoin; Retrospective Studies; Status Epilepticus; Treatment Outcome | 2023 |
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Child; Female; Hospitals, University; Humans; Lacosamide; Levetiracetam; Male; Medical Records; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid | 2023 |