phenytoin and ketamine

phenytoin has been researched along with ketamine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's4 (13.33)18.2507
2000's6 (20.00)29.6817
2010's8 (26.67)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Brown, ML; Cafiso, DS; Cechova, S; Choudhury-Mukherjee, I; Ellena, J; Kapur, J; Pajewski, TN; Schenck, HA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Evans, DE1
Zierer, R1
Gilbert, ME1
De Prins, E; Marrannes, R; Wauquier, A; Willems, R1
Clinton, ME; Dettbarn, WD; Misulis, KE1
Anderson, RJ; Raines, A2
Aldrete, JA; Cubillos, P1
Nemmer, J; Nemoto, EM; Shiu, GK1
Kayama, Y1
Callaghan, DA; Schwark, WS1
Galley, HF; Webster, NR1
Cooper, RM; Krenz, NR1
Baumbarger, DO; Jones, M; Meyer, RE; Stoskopf, MK1
Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA1
Brody, SA; Geyer, MA; Large, CH; Ong, JC1
Adams, AC; Saunders, GW; Smith, MD; White, HS; Wilcox, KS1
Cunha, AO; dos Santos, WF; Liberato, JL; Mortari, MR1
Gulati, S; Lodha, R; Raj, D1
Degirmenci, E; Erdur, B; Ergin, A; Kortunay, S; Seyit, M; Yuksel, A1
Açikkol, M; Anilanmert, B; Çavuş, F; Cengiz, S; Narin, I; Özdemir, AA; Sertler, Ş1
Keppel Hesselink, JM; Kopsky, DJ1
García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V1
Anilanmert, B; Caglar-Andac, S; Narin, I1

Reviews

2 review(s) available for phenytoin and ketamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Paediatric status epilepticus].
    Revista de neurologia, 2022, 10-16, Volume: 75, Issue:8

    Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid

2022

Other Studies

28 other study(ies) available for phenytoin and ketamine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Design, synthesis, and evaluation of analogues of 3,3,3-trifluoro-2-hydroxy-2-phenyl-propionamide as orally available general anesthetics.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Administration, Oral; Amides; Anesthetics, General; Animals; Anticonvulsants; Blood Pressure; Cells, Cultured; Drug Design; Heart Rate; Hippocampus; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoflurane; Liposomes; Magnetic Resonance Spectroscopy; Male; Mice; Propionates; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism; Structure-Activity Relationship; Xenopus

2003
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Anaesthesia and the epileptic pateint. A review.
    Anaesthesia, 1975, Volume: 30, Issue:1

    Topics: Adult; Anesthesia, General; Anticonvulsants; Barbiturates; Central Nervous System; Child, Preschool; Drug Interactions; Electroencephalography; Enzyme Induction; Epilepsy; Female; Halothane; Humans; Inactivation, Metabolic; Ketamine; Male; Methohexital; Nitrous Oxide; Phenobarbital; Phenytoin; Protein Binding

1975
Impact of ether anesthesia on the hypophyseal content of oxytocin neurophysin I and II: a comparative study with ketamine in the rat.
    Life sciences, 1991, Volume: 49, Issue:19

    Topics: Analysis of Variance; Anesthesia; Animals; Arginine Vasopressin; Atropine; Chromatography, High Pressure Liquid; Ether; Ketamine; Male; Neurophysins; Oxytocin; Phenytoin; Pituitary Gland, Posterior; Random Allocation; Rats; Rats, Inbred Strains

1991
The NMDA-receptor antagonist, MK-801, suppresses limbic kindling and kindled seizures.
    Brain research, 1988, Oct-25, Volume: 463, Issue:1

    Topics: Amygdala; Animals; Anticonvulsants; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Ketamine; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1988
Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat.
    Brain research, 1988, Aug-09, Volume: 457, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Cortical Spreading Depression; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Ketamine; Male; N-Methylaspartate; Phencyclidine; Phenytoin; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter

1988
Effects of phenytoin, ketamine, and atropine methyl nitrate in preventing neuromuscular toxicity of acetylcholinesterase inhibitors soman and diisopropylphosphorofluoridate.
    Journal of toxicology and environmental health, 1988, Volume: 24, Issue:4

    Topics: Animals; Atropine Derivatives; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate; Ketamine; Male; Muscle Contraction; Muscle Denervation; Muscles; Neuromuscular Junction; Phenytoin; Rats; Rats, Inbred Strains; Soman

1988
Suppression by diphenylhydantoin of afferent discharges arising in muscle spindles of the triceps surae of the cat.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:2

    Topics: Anesthesia; Animals; Cats; Chloralose; Depression, Chemical; Electrodes, Implanted; Hindlimb; In Vitro Techniques; Ketamine; Kinetics; Muscle Spindles; Nerve Endings; Neural Conduction; Neurons, Afferent; Phenytoin; Time Factors

1974
Selective diphenylhydantoin suppression of auditory evoked potentials in the cat cerebellar cortex.
    Neuropharmacology, 1974, Volume: 13, Issue:8

    Topics: Acoustic Stimulation; Anesthesia; Animals; Cats; Cerebellar Cortex; Chloralose; Evoked Potentials; Ketamine; Peripheral Nerves; Phenytoin; Radial Nerve

1974
Phenytoin improves hemodynamic tolerance and survival after severe hypoxia.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:11

    Topics: Anesthesia, General; Animals; Blood Pressure; Heart Rate; Hemodynamics; Hypoxia; Ketamine; Phenytoin; Rabbits; Thiopental

1984
Dose of thiopental, pentobarbital, and phenytoin for maximal therapeutic effects in cerebral ischemic anoxia.
    Critical care medicine, 1983, Volume: 11, Issue:6

    Topics: Animals; Brain Chemistry; Brain Ischemia; Fatty Acids, Nonesterified; Female; Hypoxia, Brain; Ketamine; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiopental

1983
Ketamine and e.e.g. seizure waves: interaction with anti-epileptic drugs.
    British journal of anaesthesia, 1982, Volume: 54, Issue:8

    Topics: Anesthesia, Intravenous; Animals; Cats; Drug Interactions; Electroencephalography; Evoked Potentials, Visual; Ketamine; Phenytoin; Time Factors; Trimethadione; Visual Cortex

1982
Pharmacological modification of amygdaloid-kindled seizures.
    Neuropharmacology, 1980, Volume: 19, Issue:11

    Topics: Amygdala; Animals; Diazepam; Electric Stimulation; Electrodes, Implanted; Ketamine; Male; Phenobarbital; Phenytoin; Rats; Seizures; Trimethadione

1980
Brain nitric oxide synthase activity is decreased by intravenous anesthetics.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:3

    Topics: Anesthetics, Intravenous; Animals; Anticonvulsants; Brain; Etomidate; In Vitro Techniques; Ketamine; Midazolam; Nitric Oxide Synthase; Phenytoin; Rats; Thiopental

1996
A combined cobalt and C-14 2-deoxyglucose approach to antiepileptic drug assessment.
    The International journal of neuroscience, 1996, Volume: 86, Issue:1-2

    Topics: Animals; Anticonvulsants; Antimetabolites; Autoradiography; Brain Chemistry; Cobalt; Deoxyglucose; Drug Implants; Epilepsy; Ethosuximide; Ketamine; Male; Phenytoin; Rats; Thalamus; Visual Cortex

1996
Field immobilization and euthanasia of American opossum.
    Journal of wildlife diseases, 1999, Volume: 35, Issue:1

    Topics: Analgesics; Anesthetics; Animal Welfare; Animals; Butorphanol; Drug Combinations; Euthanasia; Female; Hypnotics and Sedatives; Imidazoles; Immobilization; Ketamine; Male; Medetomidine; Muscle Relaxants, Central; Opossums; Pentobarbital; Phenytoin; Tiletamine; Zolazepam

1999
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:1

    Topics: Adult; Anticonvulsants; Atrophy; Brain; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Ketamine; Lorazepam; Magnetic Resonance Imaging; Male; Neurotoxicity Syndromes; Phenytoin; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Status Epilepticus; Valproic Acid

2003
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:3

    Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid

2005
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Count; Dose-Response Relationship, Drug; Drug Resistance; Electrophysiology; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Male; Nerve Net; Phenylenediamines; Phenytoin; Rats; Rats, Sprague-Dawley

2007
Neuroprotective effects of diazepam, carbamazepine, phenytoin and ketamine after pilocarpine-induced status epilepticus.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 104, Issue:6

    Topics: Animals; Anticonvulsants; Carbamazepine; Dentate Gyrus; Diazepam; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Hippocampus; Ketamine; Male; Maze Learning; Neuroprotective Agents; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus

2009
Status epilepticus.
    Indian journal of pediatrics, 2011, Volume: 78, Issue:2

    Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid

2011
Effects of pretreatment with etomidate, ketamine, phenytoin, and phenytoin/midazolam on acute, lethal cocaine toxicity.
    Neurological research, 2012, Volume: 34, Issue:10

    Topics: Animals; Cocaine; Disease Models, Animal; Etomidate; Ketamine; Mice; Midazolam; Phenytoin; Random Allocation; Rats; Seizures; Treatment Outcome

2012
Simultaneous analysis method for GHB, ketamine, norketamine, phenobarbital, thiopental, zolpidem, zopiclone and phenytoin in urine, using C18 poroshell column.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Jun-01, Volume: 1022

    Topics: Azabicyclo Compounds; Barbiturates; Chromatography, High Pressure Liquid; Forensic Sciences; Humans; Hypnotics and Sedatives; Ketamine; Limit of Detection; Linear Models; Liquid-Liquid Extraction; Phenytoin; Piperazines; Pyridines; Rape; Reproducibility of Results; Sodium Oxybate; Zolpidem

2016
Phenytoin in topical formulations augments pain reduction of other topically applied analgesics in the treatment of trigeminal neuralgia.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Administration, Cutaneous; Aged; Analgesics; Baclofen; Drug Synergism; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Nociceptors; Pain Management; Phenytoin; Skin Cream; Time Factors; Touch; Trigeminal Neuralgia

2017
Urgent first-step screening method for ketamine, phenobarbital, zopiclone, zolpidem, phenytoin and thiopental in adulterated soft drink.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:5

    Topics: Caffeine; Carbonated Beverages; Female; Humans; Ketamine; Phenobarbital; Phenytoin; Reproducibility of Results; Thiopental; Zolpidem

2023