phenytoin has been researched along with isoniazid in 123 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 93 (75.61) | 18.7374 |
| 1990's | 7 (5.69) | 18.2507 |
| 2000's | 9 (7.32) | 29.6817 |
| 2010's | 14 (11.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bloomer, WD; Papadopoulou, MV; Rosenzweig, HS | 1 |
| Gladkikh, SP; Piruzian, LA; Podymov, VK | 2 |
| Sinazadeh, M; Ziegler, HK | 1 |
| Kutt, H | 2 |
| Sobue, I | 1 |
| Costa, E; Guidotti, A; Mao, CC; Suria, A | 1 |
| Sotaniemi, S | 1 |
| Costa, E; Guidotti, A; Mao, CC | 1 |
| Greenblatt, DJ; Miller, RR; Porter, J | 1 |
| Destee, A; Gelez, P; Verrier, A; Warot, P | 1 |
| Draper, GJ; Sanders, BM | 1 |
| Addington, WW | 1 |
| Rapport, RL; Shaw, CM | 1 |
| Buttar, HS; Moffatt, JH; Wong, LT | 1 |
| Diukov, VA | 1 |
| Kupferberg, HJ; Sutton, G | 1 |
| Hashem, N; Shawki, R | 1 |
| Buttar, HS | 1 |
| Kirman, CS | 1 |
| Freeman, HL; Johnson, J | 1 |
| De Baere, H | 1 |
| Johnson, J | 1 |
| Lau, KS; Ling, MH; Yew, WW | 1 |
| Koide, H | 1 |
| Avasthi, R; Jain, AP | 1 |
| Jiang, M | 1 |
| Baciewicz, AM | 1 |
| Kumar, KL; Reuler, JB | 1 |
| Eto, S; Minemoto, M; Noda, A; Noda, H; Ohno, K | 1 |
| Baciewicz, AM; Self, TH | 1 |
| Delwiche, F | 1 |
| Hansen, JE; Kampmann, JP; Kay, L; Kristensen, M; Skovsted, L; Svendsen, TL; Vergman, B | 1 |
| Glogner, P | 1 |
| La Du, BN | 1 |
| Vesell, ES | 3 |
| Kutt, H; Penry, JK | 1 |
| Harpey, JP | 1 |
| Lucas, BG | 1 |
| Goedde, HW | 1 |
| Freshwater, DB; Jacques, S; Randle, RE; Shelden, CH | 1 |
| Eldredge, NT; Jiller, JJ; van Robertson, WB | 1 |
| Ganshorn, A; Kurz, H | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Lovelace, RE; Myers, SJ; Zablow, L | 1 |
| Kutt, H; Verebely, K | 1 |
| Grimm, U; Schlenzka, K | 1 |
| Dettli, L; Geering, JM; Ruch, W | 1 |
| Cohen, SN; Weber, WW | 1 |
| Fishbein, L; Flamm, WG | 1 |
| Pembrey, ME | 1 |
| Johannessen, SI; Strandfjord, RE | 1 |
| Beauvais, P; Brissaud, HE; Hanoteau, J; Mercier, D | 1 |
| Cohen, H; Langendorf, R; Pick, A | 1 |
| Goedde, W | 1 |
| Karlov, VA | 1 |
| Galea, G; Geavlete, A | 1 |
| Williams, MH | 1 |
| Du, BN | 1 |
| Evans, DA | 1 |
| el-Masry, AM; Saad, SF; Scott, PM | 1 |
| Deparis, M; Manigand, G; Thieblot, P | 1 |
| Jacobsen, CD | 1 |
| Brennan, R; Dehejia, H; Kutt, H; Verebely, K | 1 |
| Brennan, RW; Dehejia, H; Kutt, H; McDowell, F; Verebely, K | 1 |
| Glogner, P; Lange, H; Vogt, O | 1 |
| Burba, JV | 1 |
| Brennan, RW; Dehejia, H; Kutt, H; McDowell, F | 1 |
| Kutt, H; McDowell, F; Verebely, K | 1 |
| Schimke, RN | 1 |
| Dold, U; Reichenmiller, HE | 1 |
| Hynes, HE; Recker, RR | 1 |
| Kutt, H; McDowell, FH; Winters, W | 1 |
| Lee, SL; Peress, NS; Siegel, M | 1 |
| Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A | 1 |
| Perry, W; Stamp, TC | 1 |
| DeSwarte, RD | 1 |
| Kela, AK; Thulasimnay, M | 1 |
| Johansen, T; Jørgensen, L | 1 |
| Ritschel, WA; Witmer, DR | 1 |
| Desbordes, JM; Hamard, H | 1 |
| Perucca, E | 1 |
| Maddrey, WC | 1 |
| Sandyk, R | 1 |
| Linares Rodríguez, A; Recarte Alvarez, J; Rodrigo Sáez, L; Valerdiz Casasola, S | 1 |
| Dayton, PG; Olson, WA; Pruitt, AW | 1 |
| Czuczwar, SJ; Kleinrok, Z; Turski, L | 1 |
| Brouland, JP; Descotes, J; Patriarca, C; Verdier, F; Vial, T | 1 |
| Chandra, RS; Dalvi, SS; Karnad, PD; Kshirsagar, NA; Powar, HS | 1 |
| Aboo, A; Walubo, A | 1 |
| Delanty, N; French, JA; Vaughan, CJ | 1 |
| Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM | 1 |
| Fisch, P; Handgretinger, R; Schaefer, HE | 1 |
| Liebelt, EL; McElroy, EA; Shannon, M | 1 |
| JACOBZINER, H; RAYBIN, HW | 1 |
| HELFMAN, RJ | 1 |
| DAVIDSON, DS; MALLORY, GK; RODGERS, JB | 1 |
| MEILMAN, E; RAPOPORT, C; URIVETSKY, M | 1 |
| Gkiatas, K; Kararizos, G; Kararizou, E; Likomanos, D; Markou, I; Triantafyllou, N; Vassilopoulos, D; Zalonis, I; Zambelis, T | 1 |
| Fontana, RJ; Jinjuvadia, K; Kwan, W | 1 |
| Adole, PS; Kharbanda, PS; Sharma, S; Singh, A | 1 |
| Adithan, C; Subathra, A | 1 |
| Adole, PS; Kharbanda, PS; Sharma, S | 1 |
| Agrawal, M; Awasthi, R; Dahiya, R; Dua, K; Gupta, G; Mishra, A; Pathak, S; Sharma, RK | 1 |
22 review(s) available for phenytoin and isoniazid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Exogenous toxic neuropathy (author's transl)].
Topics: Acrylamides; Adolescent; Adult; Aged; Aldrin; Carbon Disulfide; Chloramphenicol; Clioquinol; DDT; Disulfiram; Endrin; Ethambutol; Female; Humans; Isoniazid; Male; Middle Aged; Nervous System Diseases; Phenytoin; Sulfonamides; Thalidomide; Thiamphenicol; Trichloroethylene; Vincristine | 1976 |
New concepts on the mechanism of action of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra | 1975 |
[Pharmacogenetic research in clinical psychiatry].
Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesterases; Drug Hypersensitivity; Enzyme Induction; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Liver; Mental Disorders; Microsomes, Liver; Monoamine Oxidase Inhibitors; Pharmacogenetics; Phenytoin; Polymorphism, Genetic; Porphyrias; Psychotropic Drugs | 1976 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Isoniazid interactions.
Topics: Animals; Antacids; Anticoagulants; Biological Availability; Carbamazepine; Drug Interactions; Food; Humans; Intestinal Absorption; Isoniazid; Phenytoin | 1985 |
Biochemical and genetic factors regulating dilantin metabolism in man.
Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines | 1971 |
Pharmacogenetics: defective enzymes in relation to reactions to drugs.
Topics: Acetylation; Cholinesterases; Coumarins; Dicumarol; Dose-Response Relationship, Drug; Female; Genetic Code; Genetic Diseases, Inborn; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Male; Metabolism, Inborn Errors; Pharmacogenetics; Phenacetin; Phenobarbital; Phenytoin; Succinylcholine | 1972 |
Advances in pharmacogenetics.
Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Environment; Female; Genetic Diseases, Inborn; Glaucoma; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant, Newborn; Intraocular Pressure; Isoniazid; Malignant Hyperthermia; Mutation; Pharmaceutical Preparations; Pharmacogenetics; Phenylthiourea; Phenytoin; Pregnancy; Protein Binding; Racial Groups; Warfarin | 1973 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Lupus-like syndromes induced by drugs.
Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis | 1974 |
Recent progress in pharmacogenetics.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin | 1969 |
Recent progress in pharmacogenetics.
Topics: Adult; Antipyrine; Cyanides; Dicumarol; Erythrocytes; Ethnicity; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Male; Middle Aged; Mutation; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Racial Groups; Taste; Twins | 1969 |
Pharmacogenetics.
Topics: Analgesics; Anemia, Hemolytic; Anesthetics; Apnea; Bone Marrow Diseases; Child; Child, Preschool; Chloramphenicol; Digitalis Glycosides; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Female; Fever; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Isoniazid; Lupus Erythematosus, Systemic; Pharmaceutical Preparations; Pharmacogenetics; Phenytoin; Pregnancy; Succinylcholine; Sulfonamides; Twins | 1972 |
Potential environmental chemical hazards. I. Drugs.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Hexachlorophene; Humans; Hydrazines; Isoniazid; Phenacetin; Phenylbutazone; Phenytoin; Procarbazine; Salicylates | 1972 |
Pharmacogenetics.
Topics: Acetyltransferases; Administration, Topical; Alleles; Analgesics; Anemia, Hemolytic; Anti-Inflammatory Agents; Antimalarials; Apnea; Base Sequence; DNA; Genes; Glucocorticoids; Glucosephosphate Dehydrogenase Deficiency; Heterozygote; Homozygote; Humans; Isoniazid; Malignant Hyperthermia; Metabolism, Inborn Errors; Mixed Function Oxygenases; Molecular Biology; Neuritis; Pharmacogenetics; Phenytoin; Succinylcholine; Sulfonamides; Sulfones | 1974 |
Pharmacogenetics.
Topics: Biotransformation; Cholinesterases; Coumarins; Genetic Variation; Genetics, Medical; Humans; Isoniazid; Liver; Metabolism, Inborn Errors; Methemoglobinemia; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenytoin; Succinylcholine | 1969 |
Genetic factors in drug therapy.
Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; Hydralazine; Isoniazid; Liver; Male; Myocardial Infarction; Pharmaceutical Preparations; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenytoin; Polymorphism, Genetic; Polyneuropathies; Streptomycin; Sulfamethazine; Tuberculosis, Pulmonary | 1969 |
[Iatrogenic pathology of the optic nerve].
Topics: Adrenal Cortex Hormones; Antiprotozoal Agents; Chloramphenicol; Contraceptives, Oral; Ethambutol; Female; Humans; Iatrogenic Disease; Isoniazid; Monoamine Oxidase Inhibitors; Optic Nerve Diseases; Phenytoin; Quinine; Radiotherapy; Surgical Procedures, Operative; Vitamins | 1982 |
Drug-related acute and chronic hepatitis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Fever; Halothane; Humans; Isoniazid; Liver; Male; Methyldopa; Middle Aged; Necrosis; Oxyphenisatin Acetate; Phenytoin | 1980 |
Medical causes of seizures.
Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Blood Pressure; Brain Diseases; Bronchodilator Agents; Coma; Confusion; Drug-Related Side Effects and Adverse Reactions; Electroencephalography; Ethanol; Humans; Isoniazid; Multiple Organ Failure; Phenytoin; Seizures; Status Epilepticus; Substance Withdrawal Syndrome; Theophylline; Water-Electrolyte Imbalance | 1998 |
Pure red cell aplasia.
Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Azathioprine; Bone Marrow Cells; Fanconi Anemia; Female; Humans; Immunosuppressive Agents; Infant; Isoniazid; Killer Cells, Natural; Leukemia, Lymphoid; Male; Parvovirus B19, Human; Phenytoin; Pregnancy; Pregnancy Complications, Hematologic; Red-Cell Aplasia, Pure; T-Lymphocytes | 2000 |
1 trial(s) available for phenytoin and isoniazid
| Article | Year |
|---|---|
Phenotypic interaction of simultaneously administered isoniazid and phenytoin in patients with tuberculous meningitis or tuberculoma having seizures.
Topics: Acetylation; Adult; Drug Interactions; Female; Humans; Isoniazid; Male; Phenotype; Phenytoin; Seizures; Time Factors; Tuberculoma; Tuberculosis, Meningeal | 2013 |
100 other study(ies) available for phenytoin and isoniazid
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
Topics: Animals; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Dose-Response Relationship, Drug; Humans; Imidazoles; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitro Compounds; Structure-Activity Relationship; Triazoles | 2017 |
[Molecular aspects of disorders in fibrillogenesis of connective tissue caused by medicinal ligands].
Topics: Animals; Connective Tissue; Humans; Hydralazine; Isoniazid; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase | 1979 |
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands].
Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; Isoniazid; Ligands; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase | 1979 |
[Anticonvulsant drugs and liver damage (Author's transl)].
Topics: Adult; Anticonvulsants; Antitubercular Agents; Autopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Epilepsy; Fatty Liver; Female; Hepatitis; Humans; Isoniazid; Liver; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Phenytoin; Tuberculosis; Tuberculosis, Miliary; Tuberculosis, Pulmonary | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
Effect of diphenylhydantoin on the apposition of dentin. An experimental study in the rat.
Topics: Alkaline Phosphatase; Animals; Body Weight; Calcium; Cholecalciferol; Connective Tissue; Dentinogenesis; Female; Isoniazid; Liver; Male; Microsomes, Liver; Odontogenesis; Organ Size; Phenobarbital; Phenytoin; Phosphates; Rats; Sex Factors | 1977 |
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam.
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine | 1975 |
Clinical importance of the interaction of phenytoin and isoniazid: a report from the Boston Collaborative Drug Surveillance Program.
Topics: Central Nervous System; Drug Interactions; Female; Humans; Isoniazid; Male; Middle Aged; Phenytoin | 1979 |
[Myoclonic encephalopathy caused by isoniazid-hydantoin combination].
Topics: Brain Diseases; Drug Therapy, Combination; Female; Humans; Isoniazid; Middle Aged; Myoclonus; Phenytoin | 1979 |
Childhood cancer and drugs in pregnancy.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Fetus; Humans; Infant; Infant, Newborn; Isoniazid; Maternal-Fetal Exchange; Neoplasms; Phenytoin; Pregnancy; Pregnancy Complications; Tuberculosis, Pulmonary | 1979 |
Medical Staff Conference. Drug-induced liver disease.
Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Drug Therapy; Female; Humans; Isoniazid; Middle Aged; Phenytoin | 1979 |
The side effects and interactions of antituberculosis drugs.
Topics: Adult; Aminosalicylic Acid; Antitubercular Agents; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Child; Drug Interactions; Ethambutol; Female; Humans; Immunosuppression Therapy; Isoniazid; Optic Neuritis; Phenytoin; Pregnancy; Rifampin; Streptomycin; Thrombocytopenia | 1979 |
Phenytoin-related cerebellar degeneration without seizures.
Topics: Cerebellum; Epilepsy; Female; Gliosis; Humans; Isoniazid; Middle Aged; Nerve Degeneration; Neuroglia; Phenytoin; Purkinje Cells; Tuberculosis, Meningeal | 1977 |
Effect of isoniazid on the metabolism of 14C-diphenylhydantoin in rats.
Topics: Animals; Body Fluids; Drug Interactions; Feces; Isoniazid; Liver; Male; Phenytoin; Rats; Time Factors; Tissue Distribution | 1978 |
Isoniazid as an inhibitor of primidone metabolism.
Topics: Depression, Chemical; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Isoniazid; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Pyridoxine; Tuberculosis, Miliary | 1975 |
Cultured peripheral lymphocytes: one biologic indicator of potential drug hazard.
Topics: Adolescent; Antimony; Antimony Potassium Tartrate; Child; Child, Preschool; Chromosomes, Human; Drug-Related Side Effects and Adverse Reactions; Epilepsy, Tonic-Clonic; Female; Humans; Isoniazid; Lymphocytes; Male; Mitosis; Niridazole; Peritonitis, Tuberculous; Phenytoin; Schistosomiasis; Tuberculosis, Pulmonary | 1976 |
Isoniazid-induced inhibition in the biotransformation of [14C] diphenylhydantoin in rat.
Topics: Animals; Bile; Biotransformation; Body Fluids; Chromatography, Paper; Depression, Chemical; Drug Interactions; Isoniazid; Liver; Male; Phenytoin; Rats; Time Factors | 1977 |
Letter: Cardiac effects of diphenylhydantoin, isoniazid, and propylene glycol.
Topics: Drug Interactions; Heart; Humans; Isoniazid; Phenytoin; Propylene Glycols | 1976 |
Death due to isoniazid (INH) and phenytoin.
Topics: Drug Interactions; Epilepsy; Female; Humans; Isoniazid; Middle Aged; Phenytoin; Tuberculosis, Lymph Node | 1976 |
[Alcohol and drugs].
Topics: Acetaldehyde; Acetyl Coenzyme A; Anesthetics; Barbiturates; Drug Interactions; Ethanol; Humans; Hypnotics and Sedatives; Intestinal Absorption; Isoniazid; Pharmaceutical Preparations; Phenytoin; Tolbutamide; Warfarin | 1976 |
Letter: Epanutin and isoniazid interaction.
Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin | 1975 |
Phenytoin toxicity in a patient with isoniazid-induced hepatitis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Interactions; Epilepsy; Female; Humans; Isoniazid; Phenytoin; Tuberculosis, Pulmonary | 1991 |
[Adverse effect of various drugs on electrolyte metabolism].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Deamino Arginine Vasopressin; Diuretics; Humans; Isoniazid; Lithium; Methoxyflurane; Phenytoin; Succinylcholine; Tetracycline; Water-Electrolyte Imbalance | 1991 |
Phenytoin--isoniazid interaction.
Topics: Adult; Cerebellar Ataxia; Drug Synergism; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Humans; Isoniazid; Male; Phenytoin; Tuberculosis, Pulmonary | 1989 |
[Primary investigation of drug-induced lupus].
Topics: Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Phenytoin | 1988 |
Drug fever.
Topics: Allopurinol; Anti-Bacterial Agents; Body Temperature Regulation; Drug Hypersensitivity; Fever; Humans; Interleukin-1; Isoniazid; Methyldopa; Phenytoin; Procainamide; Quinidine | 1986 |
Effects of isoniazid and its metabolites on phenytoin biotransformation in isolated rat hepatocytes.
Topics: Animals; Biotransformation; In Vitro Techniques; Isoniazid; Liver; Male; Phenytoin; Rats; Rats, Inbred Strains | 1987 |
[Iatrogenic coagulopathies].
Topics: Anti-Inflammatory Agents; Asparaginase; Blood Coagulation Disorders; Cephalosporins; Chlorpromazine; Hemophilia A; Humans; Isoniazid; Phenytoin; Sulfonamides | 1985 |
Influence of rifampicin and isoniazid on the kinetics of phenytoin.
Topics: Acetylation; Adult; Aged; Ethambutol; Female; Half-Life; Humans; Isoniazid; Kinetics; Male; Middle Aged; Phenotype; Phenytoin; Rifampin; Tuberculosis, Pulmonary | 1985 |
[Unfavorable and problematic drug combinations. IV].
Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Ephedrine; Humans; Hypertension; Hypotension; Isoniazid; Mercaptopurine; Methamphetamine; Microsomes, Liver; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Phenytoin; Reserpine; Stimulation, Chemical; Thiazines; Thiopental; Tyramine | 1970 |
Drugs and genes.
Topics: Acetyltransferases; Drug Antagonism; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Genes, Recessive; Humans; Isoniazid; Pharmaceutical Preparations; Phenytoin | 1973 |
"Dilantin" overdosage.
Topics: Aminosalicylic Acids; Anticonvulsants; Calcium; Dicumarol; Disulfiram; Drug Synergism; Drug Tolerance; Humans; Isoniazid; Lactose; Phenylbutazone; Phenytoin; Sulfaphenazole; Sulfates; Thiazines | 1968 |
[Pharmacogenetics: variability of drug effects and metabolic reactions].
Topics: Acetyltransferases; Anemia, Hemolytic, Congenital; Anesthesia; Animals; Biopharmaceutics; Cholinesterases; Coumarins; Dexamethasone; Dextrans; Drug Hypersensitivity; Drug Resistance; Drug Tolerance; Gene Frequency; Genetics, Population; Glucosephosphate Dehydrogenase Deficiency; Haplorhini; Hemoglobins, Abnormal; Humans; Intraocular Pressure; Isoniazid; Metabolism; Pharmacogenetics; Phenacetin; Phenytoin; Species Specificity; Succinylcholine | 1974 |
Supratentorial tuberculoma: a case report and review.
Topics: Adult; Brain Diseases; Cerebral Angiography; Dexamethasone; Diagnosis, Differential; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Isoniazid; Mycobacterium tuberculosis; Phenytoin; Rifampin; Streptomycin; Tuberculoma | 1974 |
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity | 1974 |
[Differences between the protein binding of newborns and adults and their importance for pharmacological action].
Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental | 1968 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
Sensory conduction in peroneal and posterior tibial nerves using averaging techniques.
Topics: Action Potentials; Adolescent; Adult; Aged; Computers, Analog; Diabetic Neuropathies; Electric Stimulation; Electrodes; Female; Friedreich Ataxia; Humans; Isoniazid; Male; Methods; Middle Aged; Muscular Atrophy; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; Phenytoin; Porphyrias; Tibial Nerve; Toes | 1973 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
[Studies on tryptophan metabolism in pellagra with special reference to drug-induced pellagra following INH and anticonvulsants].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Female; Humans; Isoniazid; Male; Middle Aged; Nutrition Disorders; Pellagra; Phenytoin; Tryptophan | 1974 |
[Diphenylhydantoin poisoning due to diphenylhydantoin-isoniazid interaction].
Topics: Adult; Cognition Disorders; Drug Interactions; Epilepsy; Fatigue; Humans; Isoniazid; Male; Middle Aged; Nystagmus, Pathologic; Phenytoin; Time Factors; Tuberculosis | 1974 |
[Phenytoin--blood levels and clinical aspects].
Topics: Administration, Oral; Drug Interactions; Epilepsy; Humans; Isoniazid; Phenytoin; Protein Binding; Time Factors | 1973 |
[Diphenylhydantoin poisoning induced by isoniazide. A further case].
Topics: Child; Drug Interactions; Electroencephalography; Epilepsy; Humans; Isoniazid; Male; Neurologic Manifestations; Phenytoin; Tuberculosis, Pulmonary | 1973 |
Intermittent parasystole--mechanism of protection.
Topics: Aged; Aminosalicylic Acids; Arrhythmias, Cardiac; Arteriosclerosis; Cerebrovascular Disorders; Coronary Disease; Digoxin; Electrocardiography; Furosemide; Heart Conduction System; Humans; Hypertension; Isoniazid; Kidney Failure, Chronic; Lung Diseases, Obstructive; Middle Aged; Myocardial Infarction; Phenytoin | 1973 |
[Pharmacologic basis of metabolic disturbances and drug incompatibilities].
Topics: Cholinesterases; Drug-Related Side Effects and Adverse Reactions; Isoniazid; Pharmacogenetics; Phenytoin | 1973 |
[Incompatibility of dilantin with isonicotinic acid hydrazides].
Topics: Adult; Drug Incompatibility; Epilepsy; Female; Humans; Isoniazid; Male; Middle Aged; Phenytoin; Trigeminal Neuralgia | 1973 |
[Medicaments as iatrogenic factors in the onset of lupoid syndromes].
Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Phenytoin; Procainamide | 1974 |
Special problems in respiratory diseases.
Topics: Adrenal Cortex Hormones; Aged; Aging; Anti-Bacterial Agents; Anticoagulants; Asthma; Bronchodilator Agents; Drug Interactions; Epinephrine; Humans; Hypnotics and Sedatives; Infections; Isoniazid; Lung; Lung Diseases, Obstructive; Lung Neoplasms; Phenytoin; Pulmonary Embolism; Respiratory Tract Diseases; Theophylline; Tranquilizing Agents; Tuberculosis, Pulmonary | 1974 |
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical | 1972 |
[Accidents of diphenylhydantoin induced by antituberculous treatments].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Antagonism; Ethambutol; Humans; Isoniazid; Male; Neurologic Manifestations; Phenytoin; Tuberculosis, Pleural | 1971 |
[Drug-induced anemias].
Topics: Adrenal Cortex Hormones; Anemia; Barbiturates; Bone Marrow; Chloramphenicol; Chlorpromazine; Dihydroxyphenylalanine; Gastrointestinal Hemorrhage; Gold; Humans; Hypoglycemic Agents; Indomethacin; Isoniazid; Nitrofurantoin; Phenacetin; Phenylbutazone; Phenytoin; Quinidine; Quinine; Salicylates; Sulfonamides | 1970 |
Diphenylhydantoin intoxication. A complication of isoniazid therapy.
Topics: Adolescent; Adult; Animals; Biotransformation; Cats; Epilepsy; Female; Humans; Isoniazid; Male; Middle Aged; Phenytoin; Tuberculosis | 1970 |
Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid.
Topics: Animals; Ataxia; Cats; Drug Tolerance; Epilepsy; Genetics, Medical; Humans; Isoniazid; Nystagmus, Pathologic; Phenytoin | 1970 |
[Dialysis in isoniazid poisoning].
Topics: Adolescent; Apnea; Female; Humans; Intubation, Intratracheal; Isoniazid; Middle Aged; Peritoneal Dialysis; Phenytoin; Poisoning; Renal Dialysis; Respiration, Artificial; Seizures; Shock, Septic; Thiopental | 1971 |
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione | 1968 |
Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid.
Topics: Animals; Cats; Drug Tolerance; Humans; Isoniazid; Phenytoin; Tuberculosis, Pulmonary | 1968 |
Inhibition of diphenylhydantoin metabolism in rats and in rat liver microsomes by antitubercular drugs.
Topics: Aminosalicylic Acids; Animals; Cycloserine; In Vitro Techniques; Isoniazid; Liver; Male; Microsomes; Phenytoin; Rats | 1968 |
Drugs and heredity. Pharmacogenetics--the study of heritable variations in drug response.
Topics: Drug Hypersensitivity; Genetics, Medical; Humans; Isoniazid; Metabolic Diseases; Metabolism, Inborn Errors; Pharmaceutical Preparations; Pharmacogenetics; Phenytoin; Succinylcholine | 1969 |
[Acute hepatic cell damage by simultaneous administration of isonicotinic acid hydrazide and antiepileptic agents in humans, (diphenylhydantoin or carbamazepin)].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Dibenzazepines; Drug Synergism; Female; Humans; Isoniazid; Male; Middle Aged; Phenytoin | 1969 |
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature.
Topics: Adolescent; Adult; Aminosalicylic Acids; Anemia, Aplastic; Aspirin; Barbiturates; Child; Child, Preschool; Chloramphenicol; Chlorpropamide; Colchicine; Female; Glutethimide; Heparin; Humans; Infant; Isoniazid; Male; Middle Aged; Phenytoin; Riboflavin | 1969 |
Depression of prahydroxylation of diphenylhydantoin by antituberculosis chemotherapy.
Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anticonvulsants; Ataxia; Cycloserine; Drug Incompatibility; Drug Tolerance; Epilepsy; Female; Folic Acid; Humans; Isoniazid; Male; Middle Aged; Nystagmus, Pathologic; Phenytoin; Tuberculosis | 1966 |
The epidemiology of drug-induced systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; New York City; Phenytoin; Procainamide | 1967 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
Urinary D-glucaric acid excretion during rifampicin/isoniazid and anticonvulsant enzyme induction.
Topics: Adolescent; Adult; Aged; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Glutethimide; Humans; Isoniazid; Liver; Male; Middle Aged; Phenytoin; Rifampin; Sugar Acids | 1984 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Encephalomyelitis, Acute Disseminated; Exanthema; Humans; Hydralazine; Immunity, Cellular; Isoniazid; Kidney Diseases; Liver Diseases; Lupus Erythematosus, Systemic; Lymphoid Tissue; Methyldopa; Nephritis, Interstitial; Penicillins; Phenytoin; Procainamide; Respiratory Hypersensitivity; Vasculitis, Leukocytoclastic, Cutaneous | 1984 |
Improvement of psychomotor epilepsy due to interaction of phenytoin-isoniazid.
Topics: Child; Drug Interactions; Epilepsy, Temporal Lobe; Female; Humans; Isoniazid; Phenytoin | 1984 |
Affinity of drugs for cytochrome P-450 determined by inhibition of p-nitrophenetole O-deethylation by rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme System; Disulfiram; Drug Interactions; Isoniazid; Kinetics; Male; Microsomes, Liver; Nitrobenzenes; Nitrophenols; Oxidation-Reduction; Phenytoin; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Phenytoin-isoniazid interaction: a kinetic approach to management.
Topics: Aged; Drug Interactions; Humans; Isoniazid; Kinetics; Male; Models, Biological; Phenytoin; Time Factors | 1984 |
Drug interactions in epilepsy.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Humans; Isoniazid; Phenytoin; Valproic Acid | 1980 |
Phenytoin toxicity induced by antituberculosis drugs.
Topics: Adult; Drug Interactions; Humans; Isoniazid; Male; Phenytoin; Pyrazinamide | 1982 |
[Hepatitis caused by drugs. 4].
Topics: Adult; Aminosalicylic Acid; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Halothane; Humans; Iproniazid; Isoniazid; Middle Aged; Nitrofurantoin; Phenytoin; Prognosis; Rifampin; Sulfonamides | 1982 |
Plasma concentrations of isoniazid in children with tuberculous infections.
Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Injections, Intramuscular; Isoniazid; Male; Phenytoin; Rifampin; Tuberculin Test; Tuberculosis, Meningeal; Tuberculosis, Pulmonary | 1981 |
Diphenylhydantoin potentiates the protective effect of diazepam against pentylenetetrazol but not against bicuculline and isoniazid-induced seizures in mice.
Topics: Animals; Bicuculline; Diazepam; Drug Synergism; Isoniazid; Male; Mice; Pentylenetetrazole; Phenytoin; Seizures | 1981 |
Comparison of popliteal lymph node responses in various strains of rats.
Topics: Animals; Barbital; Female; Hindlimb; Isoniazid; Lymph Nodes; Male; Phenytoin; Procainamide; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Streptozocin | 1994 |
Phenytoin toxicity due to rifampicin induced hepatic dysfunction.
Topics: Chemical and Drug Induced Liver Injury; Child; Drug Interactions; Epilepsy; Female; Humans; Isoniazid; Phenytoin; Rifampin; Tuberculosis | 1993 |
Phenytoin toxicity due to concomitant antituberculosis therapy.
Topics: Acetylation; Anticonvulsants; Antitubercular Agents; Drug Interactions; Humans; Isoniazid; Middle Aged; Phenytoin; Tuberculosis | 1995 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Toxic seizures in children: case scenarios and treatment strategies.
Topics: Adolescent; Camphor; Child, Preschool; Cocaine; Drug Interactions; Emergencies; Female; GABA Antagonists; Ginkgo biloba; Hexachlorocyclohexane; Humans; Infant; Insecticides; Isoniazid; Male; Phenytoin; Pyridines; Seeds; Seizures; Suicide, Attempted; Tachycardia | 2003 |
ISONIAZID INTOXICATIONS.
Topics: Amobarbital; Anti-Bacterial Agents; Caffeine; Child; Ions; Isoniazid; New York; Phenylephrine; Phenytoin; Protein Synthesis Inhibitors; Pyridoxine; Sodium; Sodium, Dietary; Tetracycline; Toxicology | 1964 |
TOXIC EPIDERMAL NECROLYSIS.
Topics: Amobarbital; Conjunctivitis; Drug Therapy; Humans; Isoniazid; Kanamycin; Phenytoin; Skin Diseases; Stevens-Johnson Syndrome; Toxicology | 1964 |
MASSIVE LIVER CELL NECROSIS; A RETROSPECTIVE STUDY.
Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Hepatitis A; Isoniazid; Massive Hepatic Necrosis; Pathology; Phenytoin; Postoperative Complications; Primidone; Retrospective Studies; Statistics as Topic; Sulfisoxazole; Toxicology | 1964 |
THE EFFECT OF HYDRALAZINE (APRESOLINE) ON COLLAGEN SYNTHESIS IN CARRAGEENIN GRANULOMAS.
Topics: Carrageenan; Collagen; Granuloma; Guinea Pigs; Hydralazine; Isoniazid; Pharmacology; Phenytoin; Polysaccharides; Proteins; Research; Toxicology | 1965 |
Paraneoplastic limbic encephalitis presenting as acute viral encephalitis.
Topics: Acute Disease; Acyclovir; Anti-Bacterial Agents; Anticonvulsants; Carcinoma, Renal Cell; Cerebrospinal Fluid; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Encephalitis, Viral; Enoxaparin; Ethambutol; Follow-Up Studies; Herpesvirus 1, Human; Humans; Isoniazid; Limbic Encephalitis; Limbic System; Magnetic Resonance Imaging; Male; Meningoencephalitis; Methylprednisolone; Middle Aged; Nephrectomy; Neuropsychological Tests; Paraneoplastic Syndromes, Nervous System; Phenytoin; Rifampin; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Vancomycin | 2005 |
Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.
Topics: Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; International Classification of Diseases; Isoniazid; Liver Diseases; Male; Medical Records Systems, Computerized; Michigan; Middle Aged; Phenytoin; Population Surveillance; Sensitivity and Specificity; United States; Valproic Acid | 2007 |
NAT2 gene polymorphism: covert drug interaction causing phenytoin toxicity.
Topics: Arylamine N-Acetyltransferase; Drug Interactions; Genotype; Humans; Inactivation, Metabolic; Isoniazid; Liver; Phenytoin; Polymorphism, Genetic | 2016 |
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Inactivation, Metabolic; Isoniazid; Male; Phenytoin; Pilot Projects; Polymorphism, Single Nucleotide; Seizures; Tuberculoma; Tuberculosis, Meningeal | 2016 |
Aqueous Extract of Wood Ear Mushroom, Auricularia polytricha (Agaricomycetes), Demonstrated Antiepileptic Activity against Seizure Induced by Maximal Electroshock and Isoniazid in Experimental Animals.
Topics: Agaricales; Animals; Anticonvulsants; Antitubercular Agents; Biological Products; Dose-Response Relationship, Drug; Electroshock; Isoniazid; Male; Mice; Phenytoin; Seizures; Water | 2019 |