phenytoin and hydralazine

phenytoin has been researched along with hydralazine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199019 (65.52)18.7374
1990's2 (6.90)18.2507
2000's3 (10.34)29.6817
2010's5 (17.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gladkikh, SP; Piruzian, LA; Podymov, VK2
Asboe-Hansen, G2
Kinder, S; Lubischer, A; Strong, A; Wolff, H1
Jiang, M1
Barland, P; Epstein, A1
Harpey, JP1
Eldredge, NT; Jiller, JJ; van Robertson, WB1
Greengard, P; Quinn, GP; Reid, MB1
Tovi, D1
Galea, G; Geavlete, A1
Evans, DA1
Mattila, MJ1
Ahuja, GK; Schumacher, GA1
Lee, SL; Peress, NS; Siegel, M1
DeSwarte, RD1
Wollina, U1
Coker, ST; Davidson, PP; Grissette, DE; Stewart, SE; Williams, BB1
Belfort, MA; Johnson, D; Saade, GR; Suresh, M; Vedernikov, YP1
MEILMAN, E; RAPOPORT, C; URIVETSKY, M1
Ehtisham, S; Hashmi, HA1
Harmon, M; Krassioukov, AV; Phillips, AA; Squair, JW1

Reviews

3 review(s) available for phenytoin and hydralazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis

1974
Genetic factors in drug therapy.
    The Scientific basis of medicine annual reviews, 1969

    Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; Hydralazine; Isoniazid; Liver; Male; Myocardial Infarction; Pharmaceutical Preparations; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenytoin; Polymorphism, Genetic; Polyneuropathies; Streptomycin; Sulfamethazine; Tuberculosis, Pulmonary

1969

Other Studies

26 other study(ies) available for phenytoin and hydralazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[Molecular aspects of disorders in fibrillogenesis of connective tissue caused by medicinal ligands].
    Doklady Akademii nauk SSSR, 1979, Jun-11, Volume: 246, Issue:5

    Topics: Animals; Connective Tissue; Humans; Hydralazine; Isoniazid; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase

1979
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands].
    Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; Isoniazid; Ligands; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase

1979
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1979
Drug administration in relation to meals in the institutional setting.
    Heart & lung : the journal of critical care, 1991, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biological Availability; Captopril; Drug Administration Schedule; Eating; Humans; Hydralazine; Inpatients; Middle Aged; Phenytoin; Propranolol; Quinidine; Time Factors

1991
[Primary investigation of drug-induced lupus].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1988, Volume: 10, Issue:5

    Topics: Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Phenytoin

1988
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluorescent Antibody Technique; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged; Penicillamine; Phenytoin; Procainamide

1985
The interaction of lupus-inducing drugs with deoxyribonucleic acid.
    Clinical immunology and immunopathology, 1974, Volume: 3, Issue:2

    Topics: Adult; Animals; Cattle; Child; DNA; DNA, Single-Stranded; Hot Temperature; Humans; Hydralazine; Immunodiffusion; Isoniazid; Lupus Erythematosus, Systemic; Methyldopa; Nucleic Acid Conformation; Nucleic Acid Denaturation; Optical Rotation; Oxazoles; Phenytoin; Procainamide; Propylthiouracil; Thymus Gland; Trimethadione; Viscosity

1974
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
The use of antifibrinolytic drugs to prevent early recurrent aneurysmal subarachnoid haemorrhage.
    Acta neurologica Scandinavica, 1973, Volume: 49, Issue:2

    Topics: Adult; Aged; Antifibrinolytic Agents; Blood Cell Count; Cerebral Angiography; Cyclohexanecarboxylic Acids; Factor IX; Factor V; Factor VII; Factor X; Female; Fibrin; Fibrinogen; Fibrinolytic Agents; Humans; Hydralazine; Intracranial Aneurysm; Male; Methyldopa; Middle Aged; Phenytoin; Prothrombin; Recurrence; Subarachnoid Hemorrhage

1973
[Medicaments as iatrogenic factors in the onset of lupoid syndromes].
    Medicina interna, 1974, Volume: 26, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Humans; Hydralazine; Iatrogenic Disease; Isoniazid; Lupus Erythematosus, Systemic; Middle Aged; Phenytoin; Procainamide

1974
Phenelzine, hydralazine and diphenylhydantoin.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Biotransformation; Humans; Hydralazine; Mice; Phenelzine; Phenytoin; Polymorphism, Genetic; Rabbits; White People

1970
Drug-induced systemic lupus erythematosus. Primidone as a possible cause.
    JAMA, 1966, Nov-07, Volume: 198, Issue:6

    Topics: Electroencephalography; Epilepsy; Female; Humans; Hydralazine; Hydroxychloroquine; Lupus Erythematosus, Systemic; Middle Aged; Phenobarbital; Phenytoin; Primidone

1966
The epidemiology of drug-induced systemic lupus erythematosus.
    Arthritis and rheumatism, 1967, Volume: 10, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Heart Diseases; Humans; Hydralazine; Hypertension; Isoniazid; Lupus Erythematosus, Systemic; Male; Middle Aged; New York City; Phenytoin; Procainamide

1967
Drug allergy--problems and strategies.
    The Journal of allergy and clinical immunology, 1984, Volume: 74, Issue:3 Pt 1

    Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Response Relationship, Immunologic; Drug Hypersensitivity; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Encephalomyelitis, Acute Disseminated; Exanthema; Humans; Hydralazine; Immunity, Cellular; Isoniazid; Kidney Diseases; Liver Diseases; Lupus Erythematosus, Systemic; Lymphoid Tissue; Methyldopa; Nephritis, Interstitial; Penicillins; Phenytoin; Procainamide; Respiratory Hypersensitivity; Vasculitis, Leukocytoclastic, Cutaneous

1984
[Drug-induced lupus erythematosus syndrome. Pathogenesis and relation to systemic lupus erythematosus].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Mar-01, Volume: 39, Issue:5

    Topics: Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Hydralazine; Lupus Erythematosus, Systemic; Phenylbutazone; Phenytoin; Procainamide; Syndrome

1984
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1982
Biologic interaction of gamma radiation with phenylbutazone, phenytoin, or hydralazine.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:3

    Topics: Animals; Gamma Rays; Glutathione; Hydralazine; Leukocyte Count; Liver; Male; Mice; Phenylbutazone; Phenytoin; Radiation, Ionizing

1980
Human umbilical vessels: responses to agents frequently used in obstetric patients.
    American journal of obstetrics and gynecology, 1995, Volume: 172, Issue:5

    Topics: Analysis of Variance; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hydralazine; In Vitro Techniques; Magnesium Sulfate; Phenytoin; Pregnancy; Pregnancy Complications; Umbilical Arteries; Umbilical Veins; Vasodilation

1995
THE EFFECT OF HYDRALAZINE (APRESOLINE) ON COLLAGEN SYNTHESIS IN CARRAGEENIN GRANULOMAS.
    Arthritis and rheumatism, 1965, Volume: 8

    Topics: Carrageenan; Collagen; Granuloma; Guinea Pigs; Hydralazine; Isoniazid; Pharmacology; Phenytoin; Polysaccharides; Proteins; Research; Toxicology

1965
Posterior reversible encephalopathy syndrome.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:6

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Female; Humans; Hydralazine; Magnetic Resonance Imaging; Phenytoin; Posterior Leukoencephalopathy Syndrome; Prazosin; Puerperal Disorders

2012
Emergency management of autonomic dysreflexia with neurologic complications.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2016, Oct-18, Volume: 188, Issue:15

    Topics: Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Autonomic Dysreflexia; Brain; Consciousness Disorders; Diffusion Magnetic Resonance Imaging; Emergencies; Humans; Hydralazine; Hypertension; Hypnotics and Sedatives; Intubation, Intratracheal; Kidney Calculi; Magnetic Resonance Imaging; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Phenytoin; Posterior Leukoencephalopathy Syndrome; Propofol; Respiration, Artificial; Seizures; Spinal Cord Injuries; Staphylococcal Infections; Thoracic Vertebrae; Tomography, X-Ray Computed; Urinary Tract Infections

2016