phenytoin has been researched along with hydantoins in 320 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 300 (93.75) | 18.7374 |
| 1990's | 11 (3.44) | 18.2507 |
| 2000's | 5 (1.56) | 29.6817 |
| 2010's | 3 (0.94) | 24.3611 |
| 2020's | 1 (0.31) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Roger, J; Tassinari, CA | 1 |
| Canonne, MA; Hue, G; Landriau, N; Maitrot, B; Rocher, A | 1 |
| Baskin, SI; Cohn, EM; Leibman, AJ | 1 |
| Lawrence, RC; Lovering, EG; Watson, JR | 1 |
| Bedoya, V; Krueger, GR | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 1 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Glazko, AJ | 1 |
| Hayden, M | 1 |
| MacKinney, AA; Vyas, RS; Walker, D | 1 |
| Rosenmund, H; Wad, N | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Conard, GJ; Osborn, JC; Pekary, AD; Scholle, RH | 1 |
| Wörle, M | 1 |
| O'Dea, MH; Reinhard, JF; Samour, CM; Vida, JA | 1 |
| Ellis, RH; Leighton, M; Simpson, P; Tatham, P; Williams, J | 1 |
| MacKinney, AA; Vyas, R | 1 |
| Ojemann, LM; Troupin, AS | 1 |
| Brien, JF; Inaba, T; Kalow, W | 1 |
| Buswink, AA; Counsell, RE; Hong, BH; Kline, W; Ranade, VV | 1 |
| Eto, S; Noda, A; Noda, H | 1 |
| Ager, PL; Buehler, BA; Finnell, RH; Kerr, BM; Levy, RH | 1 |
| Pezeshk, A; Pezeshk, V | 1 |
| Acuff-Smith, KD; Minck, DR; Vorhees, CV | 1 |
| Berg, MJ; Olson, CH; Van Dyke, DC | 1 |
| Geiger, SA; Peuten, M | 1 |
| Breimer, DD; Schellens, JH; van der Wart, JH | 1 |
| Brown, LP; Flint, OP; Gibson, GG; Lewis, DF; Orton, TC | 1 |
| Janis, LJ; Miller, TD; Pinkerton, TC | 1 |
| Branch, RA; Guengerich, FP; Hall, SD; Wilkinson, GR | 1 |
| Higashi, A; Inotsume, N; Kinoshita, E; Matsuoka, T; Nakano, M | 1 |
| Tompkins, JE | 1 |
| Blouin, RA; Brazzell, RK; McNamara, PJ | 1 |
| Lee, HS; Tan, SF; Wong, PT | 1 |
| Bardy, A; Gaily, E; Granström, ML; Hiilesmaa, V | 1 |
| Goldman, AS; Gupta, C; Katsumata, M; Van Dyke, DC | 1 |
| Dyderski, S; Jankowiak, M; Masiakowski, J; Wierzchowiecki, M | 1 |
| Buniatian, IuA; Dzhagatspanian, SA | 1 |
| Davidson, S; Falconer, MA | 1 |
| Forrest, TP; Gilroy, ML; Vohra, MM; Yung, DK | 1 |
| Kyogoku, Y; Yu, NT | 1 |
| Deitrich, RA; Erwin, VG | 1 |
| Sibley, WA | 1 |
| Jones, GL; Kemp, JW | 1 |
| Afifi, AK; Van Allen, MW | 1 |
| Brock, JT; Cereghino, JJ; Ellenberg, J; Fisher, P; Penry, JK; Smith, LD; Van Meter, JC | 1 |
| Goodwin, BB; Siegel, GJ | 1 |
| Raines, A; Standaert, FG | 1 |
| Collard, M; Coquillat, G; Rohmer, F; Warter, JM | 1 |
| Elliott, TH; Natarajan, PN | 1 |
| Rümke, CL | 1 |
| Buttler, R; Goenechea, S; Paulus, W | 1 |
| Kutt, H; Verebely, K | 1 |
| Mandel, HG; Riis, M | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Toothill, C | 1 |
| Dressler, WE; Orzechowski, RF; Rossi, GV | 1 |
| Leibovitz, U | 1 |
| Grossmann, W; Jurna, I; Richter, D | 1 |
| Grossmann, W; Jurna, I | 1 |
| Becker, BA; Harbison, RD | 1 |
| Wildhack, R | 1 |
| Drizhal, I; Hrdinová, V | 1 |
| Beil, E; Prechtel, K | 1 |
| Rodgers, G; Roger, JC; Soo, A | 1 |
| Inglis, AS; Nicholls, PW | 1 |
| Bochner, F; Eadie, M; Hooper, W; Tyrer, J | 1 |
| Gillis, RA; Raines, A | 1 |
| Meyer, JG | 1 |
| Heischkeil, R | 1 |
| Buchanan, RA; Serrano, EE; Wilder, BJ | 1 |
| Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM | 1 |
| Inglis, AS; Nicholls, PW; Sparrow, LG | 1 |
| Grossmann, W; Jurna, I; Nehles, J | 1 |
| Gottwald, W | 1 |
| Brendel, K; Bressler, R; Kizer, JS; Vargas-Gordon, M | 1 |
| Ristić, J | 1 |
| Babcock, JR; Commiskey, LV; White, GO | 1 |
| Hyman, GA; Sommers, SC | 1 |
| Parrow, A | 1 |
| Millichap, JG; Ortiz, WR | 1 |
| Conrad, FG; Gams, RA; Neal, JA | 1 |
| Goldensohn, ES; Masland, W; Walsh, GO | 1 |
| el-Masry, AM; Saad, SF; Scott, PM | 1 |
| Grob, PJ; Herold, GE | 1 |
| Erdey, L; Káplár, L; Takács, J | 1 |
| Norski, T | 1 |
| Chang, T; Glazko, AJ | 1 |
| Bercel, NA; Henstell, HH | 1 |
| Chang, T; Glazko, AJ; Savory, A | 1 |
| Handley, AJ | 1 |
| Blackburn, WH; Napoli, MD; Wallin, RF | 1 |
| Kutt, H; Levitt, B; Raines, A; Sohn, YJ; Verebely, K | 1 |
| Jensen, ON; Olesen, OV | 1 |
| Hammer, RH; Mayersdorf, A; Streiff, RR; Wilder, BJ | 1 |
| De Santis, AM; Novelli, A | 1 |
| McGregor, JG; Schreiber, MM | 1 |
| Krimsley, V; Shaffer, JW; Steinberg, E; Winstead, WB | 1 |
| Jenny, E; Solberg, R | 1 |
| Gillen, HW; Pippenger, CE; Scott, JE | 1 |
| Gillen, HW; Pippenger, CE | 1 |
| Guggenheim, P; Regli, F | 1 |
| Fujimoto, K; Hirooka, T; Nakamura, K; Nakatsuji, K; O'Hashi, K; Ose, S | 1 |
| Bartels, E; Rosenberg, P | 1 |
| Allen, RW; Jung, AL | 1 |
| Kamińska, A; Rydzik, E; Szadowska, A | 1 |
| Meinardi, H | 1 |
| Kusowska, J; Ryczek, J | 1 |
| Daniels-McQueen, S; Ferrendelli, JA | 1 |
| Roeda, D; Westera, G | 1 |
| Avendaño, MC; Ballesteros, P; Cañadas, S; González, MP | 1 |
| Allen, RW; Bentley, FL; Jung, AL; Ogden, B | 1 |
| Karolak-Wojciechowska, J; Kiec-Kononowicz, K; Kwiatkowski, W | 1 |
| Belica, PS; Lubet, RA; Manchand, PS; McClain, RM; Mellini, DW; Nims, RW; Thomas, PE; Utermahlen, WE | 1 |
| Ishikawa, A; Misawa, S; Tanaka, E | 1 |
| Haimova, M; Marintchev, A; Mirtcheva, J; Sidjimov, A | 1 |
| Kohn, H; LeTiran, A; Stables, JP | 1 |
| KING, JD | 1 |
| COHEN, JD; MORRIS, GE | 1 |
| CHEN, G; ENSOR, CR | 2 |
| FROMMEL, E; GOLD, P; RADOUCO, C | 1 |
| KOHLHEPP, B | 1 |
| KLOSA, J | 1 |
| MASI, P | 2 |
| SAUTER, EK | 1 |
| TATERKA, JH; THOMPSON, CB | 1 |
| STAPLE, PH | 2 |
| DESTUNIS, G | 1 |
| BLAKE, FS; BLAKE, H | 1 |
| FROMMEL, E; RADOUCO-THOMAS, C | 1 |
| DE GOMES, JC | 1 |
| CHABRIER, P; SMARZEWSKA, K; THUILLIER, G | 1 |
| JENSEN, HP | 1 |
| PETERS, JJ; VONDERAHE, AR | 1 |
| MOSEY, L; TYLER, MD | 1 |
| SWENSON, HM | 1 |
| HAWKINS, CF; MEYNELL, MJ | 1 |
| RHIND, EG; VARADI, S | 1 |
| GRAVELEAU, J; LEVEAU, J; MORIN, M | 1 |
| BARME, M; MARTIN, R; SUREAU, B; VERON, M | 1 |
| ENDROCZI, E; LISSAK, K; SZEREDAY, Z | 1 |
| FINCH, E; LORBER, J | 1 |
| BERTRAND, I; GAYET-HALLION, T; QUIVY, D | 1 |
| MATHIS, H | 1 |
| ENDROCZI, E; LISSAK, K; SZEREDAI, Z | 1 |
| WINIKER-BLANCK, E | 1 |
| BOKS, LL; LIVINGSTON, S; PETERSEN, D | 1 |
| WOODBURY, DM | 1 |
| DRUCKMAN, R; MOORE, FJ | 1 |
| MURPHY, JT; SCHWAB, RS | 1 |
| MELIN, KA; WALLER, G | 1 |
| GROPPER, AL | 1 |
| VAN DER KWAST, WA | 1 |
| HUYCK, CL; WIEGAND, CF | 1 |
| GINSBERG, V; GOLD, JA; ISAACSON, S | 1 |
| HINE, CH; PLAA, GL | 1 |
| RAFFI, A | 1 |
| BERGIN, JT; FISCHER, E; MORRIS, JV | 1 |
| DILL, WA; GLAZKO, AJ; KAZENKO, A; WOLF, LM | 1 |
| BONNYCASTLE, DD; GIARMAN, NJ; PAASONEN, MK | 1 |
| LIVINGSTON, S | 2 |
| GOODMAN, LS; SWINYARD, EA; TEDESCHI, DH | 1 |
| VETTORI, D | 1 |
| GAILLARD, RA | 1 |
| GYDELL, K | 1 |
| VON KNORRE, G | 1 |
| BROWNLEE, G; GORVIN, JH | 1 |
| ENDE, M | 1 |
| BENIANS, RC; HUNTER, RA | 1 |
| ESPLIN, DW | 1 |
| CECIL, HC; FORSCHER, BK | 1 |
| BREG, WR; FALCETTI, JP | 1 |
| MOLING, JH; POSCH, JJ | 1 |
| BHANSALI, K; BLAUG, SM; LACH, JL | 1 |
| CARTER, CH | 1 |
| BAKER, AB; IANNONE, A; MORRELL, F | 1 |
| BRADLEY, W; MORRELL, F; PTASHNE, M | 1 |
| HOFMANN, WW | 1 |
| LEONARD, WA | 1 |
| CASPERS, H; WEHMEYER, H | 1 |
| SHAPIRO, M | 1 |
| CHITI, W; SELLERI, R | 2 |
| GOODMAN, LS; NOACH, EL; WOODBURY, DM | 1 |
| BEATTY, RE; DAVIS, WB; SHAFER, WG | 1 |
| BUCHTHAL, F; SCHILLER, PJ | 1 |
| GILSTER, JE; HOLOWACH, J; THURSTON, DL | 1 |
| FONTEIN, MT; VAN NISPEN TOT PANNERDEN, EB | 1 |
| KHUBAVENKOVA, A; ZAIMOVA, N | 1 |
| CHIARINI, P; CHITI, W | 1 |
| GOODMAN, LS; SWINYARD, EA; WEAVER, LC | 1 |
| STURMER, FC | 1 |
| BERGOUIGNAN, M | 1 |
| GRAY, WD; LIPCHUCK, LM; OSTERBERG, AC; RAUH, CE | 1 |
| KARLOVA, NP | 1 |
| KIVALO, E; MARJANEN, P; TYRKKO, J | 1 |
| McWILLIAM, PK | 1 |
| BRAY, PF | 1 |
| DUTTON, P | 1 |
| HOWARD, WL; INGLE, JI; ZWICK, HH | 1 |
| BOHNER, B; CHEN, G; ENSOR, CR | 1 |
| CHRISTY, NP; HOFMANN, AD | 1 |
| CARLEN, SA | 1 |
| MANLAPAZ, JS | 1 |
| AGUILERA MARURI, C | 1 |
| FLOYD, FW | 1 |
| GREEN, JB | 1 |
| HOUCK, JC; JACOB, RA; MAENGWYN-DAVIES, GD | 1 |
| EISSNER, H | 1 |
| ROSEMAN, E | 1 |
| MORRISON, AN; ROSENFELD, S; SHENOY, YM; SWILLER, AI | 1 |
| BLUMENFELD, S; SCHERF, D; TANER, D; YILDIZ, M | 1 |
| SHAFER, WG | 3 |
| KURTZKE, JF | 1 |
| LIVINGSTON, S; PAULI, LL; WHITEHOUSE, D | 1 |
| LOESER, EW | 1 |
| LOW, NL; YAHR, MD | 1 |
| DRESKIN, OH; GOLDMAN, D; LUSTBERG, A | 1 |
| LEFEVRE, AB; MANISSADJIAN, A; PENNA, HA | 1 |
| MAYNERT, EW | 1 |
| DOOLAN, PD; POWELL, MR; RICHTER, RW; THEIL, GB | 1 |
| NICKLAS, TO; WAITES, L | 1 |
| CAHEN, RL; GOODMAN, LS | 1 |
| CHRISTENSEN, K | 1 |
| BERTRAND, I; GAYET-HALLION, T | 1 |
| GAYET-HALLION, T | 1 |
| STILLE, G | 1 |
| BUCHTHAL, F; SCHILLER, PJ; SVENSMARK, O | 1 |
| TURNER, P | 1 |
| BUCHTHAL, F; SVENSMARK, O | 1 |
| BIEDEBACH, F; MANNS, G | 1 |
| ASTON, R; DOMINO, EF | 1 |
| BAJOGHLI, M | 1 |
| CHUNG, AC; HOUCK, JC | 1 |
| CARTER, WW; ESSIG, CF | 1 |
| FUKAI, H; NAKAI, S; SATO, S; WATANABE, S | 1 |
| BROUN, GO; SLAVIN, RG | 1 |
| CLARK, PG; STANDISH, SM | 1 |
| NUTTER, DJ; STAPLE, PH | 1 |
| FISHMAN, RA; TRIEDMAN, HM; YAHR, MD | 1 |
| VIUKARI, M | 1 |
| OPPENHEIMER, JH; TAVERNETTI, RR | 2 |
| HOUCK, JC | 2 |
| ALEXANDER, B; PECHET, L; WEINTRAUB, RM | 1 |
| BOND, WH; CHILDRESS, RH; LONG, MT | 1 |
| PANALAKS, T | 1 |
| CORRIOL, J; JOANNY, P; MILLET, Y | 1 |
| BONARD, EC | 1 |
| CORRIOL, J; FONDARAI, J; JOANNY, P | 1 |
| JONGMANS, JW | 1 |
| GRANT, WM; PECZON, JD | 1 |
| TOMPSETT, SL | 1 |
| BILLEN, JR; GRIFFIN, JW; WALDRON, CA | 1 |
| MACGEE, J; SHOLITON, LJ; WERK, EE | 1 |
| BASSASGRAU, M; DEMARTINGASSO, C; ORIOLMERCADALPEYRI, J | 1 |
| AOKI, Y; FUKUI, S; KISHI, Y; MANMARU, S | 1 |
| GOLD, P; RADOUCO-THOMAS, C; RADOUCO-THOMAS, S | 1 |
| MEGIRIAN, R; SWISS, ED; WHITE, CW | 1 |
| GOODMAN, LS; SWINYARD, EA; WEAVER, LC; WOODBURY, LA | 1 |
| BALIER, C; MARCHAND, L; TEULIE, G | 1 |
| BONNY-CASTLE, DD; COSTA, PJ; GLASER, GH | 1 |
| FORSHAW, JW; RYAN, GM | 1 |
| HANBERY, JW; HOFMANN, WW; KOENIG, G; SHUMWAY, NE | 1 |
| AGUILAR, A; BURNETT, WW; MARTIN, HL; MAVOR, H; MCNAUGHTON, F | 1 |
| OTTOSSON, JO | 1 |
| PYLKKO, OO; WOODBURY, DM | 1 |
| CHIARINI, P; CHITI, W; SUPERBI, C | 1 |
| KONRAD, JN | 1 |
| KRIEGER, DT | 1 |
| LINDBLOM, U | 1 |
| FINGER, KF; FUNDERBURK, WH; P'AN, SY | 1 |
| FURUHJELM, U; RANTAKALLIO, P | 1 |
| SWINYARD, EA; TOMAN, JE | 1 |
| SELIGER, H | 1 |
| HARRIS, AS; KOKERNOT, RH | 1 |
| KOREY, SR | 1 |
| UNIKER, TE | 1 |
| RUSKIN, DB | 1 |
| ARLOTTA, P | 1 |
| HUSTON, MJ; RIEDEL, BE | 1 |
| ENSELBERG, CD; TICHNER, JB | 1 |
| AIRD, RB; STRAIT, L | 1 |
| BORKOWSKI, W; HOLT, WL | 1 |
| FASMAN, GD; FOSTER, RJ; VAN HARREVELD, A | 1 |
| SANDBERG, F | 1 |
| HØYRUP, E; VINTEN JOHANSEN, E | 1 |
| Jones, JP; Kneller, MB; Rettie, AE; Rock, DA; Suzuki, H; Trager, WF | 1 |
| READER, ZA | 1 |
| BERNHARDT, H | 1 |
| SWEET, RD | 1 |
| ROWNTREE, LG; WAGGONER, RW | 1 |
| FRANK, ME; PRICE, WC | 1 |
| CHAIKEN, BH; GOLDBERG, BI; SEGAL, JP | 1 |
| HELLER, G; SLOANE, M | 1 |
| DUBOIS, EL | 1 |
| LIVINSTON, S; SWEET, AY | 1 |
| GELLER, W | 1 |
| HEJTMANCIK, MR; MIDDLETON, JW | 1 |
| WEINLAND, WL | 1 |
| Batts, TW; Brown, ML; Davis, GC; Hartmann, HA; Jones, PJ; Ko, SH; Lenkowski, PW; McCusker, AK; Patel, MK; Smith, MD; Taylor, CH; White, HS | 1 |
| Kang, HE; Kim, YC; Lee, MG | 1 |
| MARTIN, RE; McGOVERN, JP | 1 |
| BLAIR, D | 1 |
| GOODMAN, LS; SWINYARD, EA; TOMAN, JE | 1 |
| HANZLIK, PJ; LAQUEUR, GL | 1 |
| Filipek, B; Handzlik, J; Kieć-Kononowicz, K; Kubacka, M; Mogilski, S; Nędza, K; Siwek, A; Szymańska, E | 1 |
| Campagne, JM; Colacino, E; de Figueiredo, RM; Konnert, L; Lamaty, F; Martinez, J; Reneaud, B | 1 |
| Iwai, M; Kondo, F; Ogawa, T; Seno, H; Suzuki, T; Ueyama, J | 1 |
| Kato, K; Kawami, M; Kumamoto, T; Shintani, Y; Takano, M | 1 |
10 review(s) available for phenytoin and hydantoins
| Article | Year |
|---|---|
Possible functions of taurine in the central nervous system.
Topics: Aging; Animals; Anticonvulsants; Behavior, Animal; Biological Transport, Active; Brain; Cats; Denervation; Eye; Hydantoins; Lens, Crystalline; Mice; Neurotransmitter Agents; Organ Specificity; Phenytoin; Rats; Spinal Cord; Taurine | 1976 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
Differences in phenytoin biotransformation and susceptibility to congenital malformations: a review.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Disease Susceptibility; Epoxide Hydrolases; Female; Fetus; Glutathione Transferase; Humans; Hydantoins; Phenytoin; Polymorphism, Restriction Fragment Length; Pregnancy; Tetrahydrofolate Dehydrogenase | 1991 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Histamine H1 Antagonists; Humans; Hydantoins; Hypnotics and Sedatives; Infant, Newborn; Myoclonus; Phenobarbital; Phenytoin; Primidone; Sleep | 1974 |
Current drug therapy--antiepilepsy agents.
Topics: Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Drug Interactions; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Intestinal Absorption; Microsomes, Liver; Motor Cortex; Myoclonus; Oxyphenbutazone; Phenytoin; Skin Manifestations; Structure-Activity Relationship; Succinimides | 1974 |
[The action of hydantoinate in the organism during the therapy of epilepsy with special reference to the origin of gingival hyperplasia. Review II].
Topics: Animals; Culture Techniques; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin | 1972 |
[On the clinical features, histology and etiology of gingival hyperplasia and the hydantoins].
Topics: Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin | 1969 |
[General review of the present therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Succinimides | 1971 |
SEDATIVES, STIMULANTS, AND INTRAOCULAR PRESSURE IN GLAUCOMA.
Topics: Anticonvulsants; Barbiturates; Caffeine; Central Nervous System Stimulants; Dextroamphetamine; Glaucoma; Hydantoins; Hypnotics and Sedatives; Intraocular Pressure; Meperidine; Mephenesin; Meprobamate; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pharmacology; Phenytoin; Primidone; Promethazine; Reserpine; Tonometry, Ocular; Tranquilizing Agents | 1964 |
2 trial(s) available for phenytoin and hydantoins
| Article | Year |
|---|---|
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutics; Chromatography, Thin Layer; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Hydantoins; Male; Middle Aged; Nausea; Phenobarbital; Phenytoin; Placebos; Primidone; Spectrophotometry; Statistics as Topic; Thiohydantoins; Time Factors; Vomiting | 1974 |
Albutoin, a new thiohydantoin derivative for grand mal epilepsies. Comparison with diphenylhydantoin in a double-blind, controlled study.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Hydantoins; Infant; Male; Myoclonus; Phenytoin | 1967 |
308 other study(ies) available for phenytoin and hydantoins
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Prognosis; Succinimides; Thiazines; Valproic Acid | 1975 |
[Determination of phenobarbital, mephenytoin and diphenylhydantoin in the surveillance of anticonvulsant treatment].
Topics: Barbiturates; Child; Chromatography, Gas; Epilepsy; Ether; Humans; Hydantoins; Mephenytoin; Methylation; Phenobarbital; Phenytoin; Solvents; Temperature | 1976 |
Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.
Topics: Anticonvulsants; Chromatography, Gas; Glutethimide; Hydantoins; Mephenytoin; Phenytoin; Primidone; Succinimides | 1978 |
Ultrastructural studies on hydantoin induced lymphomas in mice.
Topics: Animals; Female; Hydantoins; Lymphoma; Mice; Phenytoin | 1978 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
Antiepileptic drugs: biotransformation, metabolism, and serum half-life.
Topics: Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biotransformation; Carbamazepine; Half-Life; Humans; Hydantoins; Oxazoles; Phenylurea Compounds; Phenytoin; Primidone; Succinimides; Sulfonamides | 1975 |
The fetal hydantoin syndrome. A case report.
Topics: Abnormalities, Drug-Induced; Adult; Epilepsy; Female; Fetus; Humans; Hydantoins; Infant; Male; Phenytoin; Pregnancy; Pregnancy Complications | 1978 |
Hydantoin drugs inhibit polymerization of pure microtubular protein.
Topics: Animals; Centrifugation; Depression, Chemical; Glycoproteins; Hydantoins; In Vitro Techniques; Microscopy, Electron; Microtubules; Phenytoin; Polymers; Protein Binding; Ribonucleotides; Swine; Tubulin; Viscosity | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Relationship of drug metabolism and inflammation to the gingival response of rats treated with diphenylhydantoin.
Topics: Alveolar Process; Animals; Diet, Cariogenic; Disease Models, Animal; Female; Gingival Hyperplasia; Gingivitis; Hydantoins; Ligation; Phenytoin; Rats; Tooth | 1975 |
[Prospects of surgical treatment in hydantoin-induced gingival hyperplasia].
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Hydantoins; Male; Phenytoin; Recurrence | 1976 |
Anticonvulsants. 5. Derivatives of 5-ethyl-5-phenylhydantoin and 5,5-diphenylhydantoin.
Topics: Animals; Anticonvulsants; Depression, Chemical; Electroshock; Hydantoins; Lethal Dose 50; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Reflex; Seizures; Sleep | 1975 |
The cardiovascular effects of dantrolene sodium in dogs.
Topics: Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Dantrolene; Dogs; Electrocardiography; Heart; Heart Rate; Hydantoins; Injections, Intravenous; Phenytoin; Sodium Chloride | 1975 |
Effects of 5,5-diphenylhydantoin and related carbamates and hydroxylamines on nucleic acid and protein synthesis of proliferating human lymphocytes.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Blood Proteins; Carbamates; DNA; Humans; Hydantoins; Hydroxyacetylaminofluorene; Hydroxylamines; In Vitro Techniques; Leucine; Lymphocytes; Phenytoin; Structure-Activity Relationship; Thymidine | 1975 |
Paradoxical intoxication--a complication of anticonvulsant administration.
Topics: Carbamazepine; Drug Therapy, Combination; Humans; Hydantoins; Mephenytoin; Phenytoin; Seizures | 1975 |
Comparative drug elimination in man-diphenylhydantoin and amobarbital.
Topics: Adult; Amobarbital; Biotransformation; Half-Life; Humans; Hydantoins; Kinetics; Male; Middle Aged; Phenytoin | 1975 |
Potential organ or tumor imaging agents XV: radioiodinated phenytoin derivatives.
Topics: Animals; Female; Hydantoins; Phenytoin; Rats; Time Factors | 1976 |
Chiral separation of barbiturates and hydantoins by reversed-phase high-performance liquid chromatography using a 25 or 50 mm short ODS cartridge column via beta-cyclodextrin inclusion complexes.
Topics: Barbiturates; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Humans; Hydantoins; Mephobarbital; Phenytoin; Stereoisomerism | 1992 |
Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Anticonvulsants; Body Weight; Dioxolanes; Epoxide Hydrolases; Female; Fetal Diseases; Fetus; Humans; Hydantoins; Mice; Mice, Inbred Strains; Microsomes; Phenytoin; Pregnancy; Syndrome | 1992 |
Drug-metal interactions: spectroscopic studies of copper hydantoin complexes.
Topics: Copper; Crystallization; Electron Spin Resonance Spectroscopy; Hydantoins; Mephenytoin; Molecular Structure; Phenytoin; Pyridines; Spectrophotometry, Infrared | 1991 |
Comparison of the behavioral teratogenic potential of phenytoin, mephenytoin, ethotoin, and hydantoin in rats.
Topics: Animals; Behavior, Animal; Ear, Inner; Female; Hydantoins; Male; Mephenytoin; Phenytoin; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1991 |
[Treatment of neuralgiform maxillofacial pain with hydantoin (Phenhydan)].
Topics: Adult; Aged; Carbamazepine; Drug Combinations; Facial Neuralgia; Female; Humans; Hydantoins; Male; Middle Aged; Phenytoin | 1990 |
Relationship between mephenytoin oxidation polymorphism and phenytoin, methylphenytoin and phenobarbitone hydroxylation assessed in a phenotyped panel of healthy subjects.
Topics: Adult; Female; Humans; Hydantoins; Hydroxylation; Male; Mephenytoin; Oxidation-Reduction; Phenobarbital; Phenotype; Phenytoin | 1990 |
Teratogenicity of phenylhydantoins in an in vitro system: molecular orbital-generated quantitative structure-toxicity relationships.
Topics: Animals; Cells, Cultured; Female; Hydantoins; Molecular Conformation; Phenytoin; Pregnancy; Rats; Structure-Activity Relationship; Teratogens | 1989 |
Effect of protein binding on the high-performance liquid chromatography of phenytoin and imirestat in human serum by direct injection onto internal surface reversed-phase columns.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Fluorenes; Humans; Hydantoins; Phenytoin; Protein Binding; Spectrophotometry, Ultraviolet | 1989 |
Characterization and inhibition of mephenytoin 4-hydroxylase activity in human liver microsomes.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; Hydantoins; Isoenzymes; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenytoin; Polymorphism, Genetic; Stereoisomerism; Warfarin | 1987 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
5,5-Diaryl-2-thiohydantoins and 5,5-diaryl-N3-substituted-2-thiohydantoins as potential hypolipidemic agents.
Topics: Animals; Dose-Response Relationship, Drug; Hydantoins; Hypolipidemic Agents; Male; Orotic Acid; Phenytoin; Rats; Rats, Inbred Strains; Thiohydantoins; Triglycerides | 1986 |
The protein binding of phenytoin, propranolol, diazepam, and AL01576 (an aldose reductase inhibitor) in human and rat diabetic serum.
Topics: Adult; Aldehyde Reductase; Animals; Blood Glucose; Blood Proteins; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diazepam; Fluorenes; Humans; Hydantoins; Male; Phenytoin; Propranolol; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Sugar Alcohol Dehydrogenases | 1988 |
N-demethylation of methyl and dimethyl derivatives of phenytoin and their anticonvulsant activities in mice.
Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Electroshock; gamma-Aminobutyric Acid; Hydantoins; Injections, Intraperitoneal; Male; Mephenytoin; Mice; Mice, Inbred Strains; Phenytoin; Radioligand Assay | 1988 |
Minor anomalies in offspring of epileptic mothers.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Child; Child, Preschool; Congenital Abnormalities; Epilepsy; Female; Humans; Hydantoins; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Syndrome | 1988 |
Elevated glucocorticoid receptor levels in lymphocytes of children with the fetal hydantoin syndrome (FHS).
Topics: Abnormalities, Drug-Induced; Child; Female; Fetal Diseases; Humans; Hydantoins; Lymphocytes; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Glucocorticoid; Syndrome | 1987 |
[Serum phenytoin level after long-term administration of 3 preparations of the drug to patients with arrhythmia].
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Hydantoins; Male; Middle Aged; Phenytoin | 1987 |
[Determination of the active substance of a rovral preparation in biosubstrates].
Topics: Aminoimidazole Carboxamide; Animals; Chromatography, Thin Layer; Fungicides, Industrial; Hydantoins; Imidazoles; Phenytoin; Rats | 1986 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Alkylation reactions of hydantoins and succinimides.
Topics: Alkylation; Animals; Anticonvulsants; Benzyl Compounds; Chemical Phenomena; Chemistry; Ethosuximide; Hydantoins; Magnetic Resonance Spectroscopy; Male; Mice; Nitro Compounds; Pentylenetetrazole; Phenytoin; Spectrophotometry, Infrared; Succinimides | 1973 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione | 1973 |
Characteristics of the hydrogen bonding interactions of substituted hydantoins with 9-ethyladenine.
Topics: Adenine; Chemical Phenomena; Chemistry; Dimethyl Sulfoxide; Ethane; Hydantoins; Magnetic Resonance Spectroscopy; Phenytoin; Spectrophotometry, Infrared; Structure-Activity Relationship | 1974 |
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvulsive Therapy; Electroencephalography; Epilepsy, Tonic-Clonic; Facial Muscles; Female; Gait; Humans; Hydantoins; Intellectual Disability; Neurocognitive Disorders; Nystagmus, Pathologic; Phenytoin; Primidone; Psychological Tests; Purkinje Cells; Schizophrenia; Staining and Labeling | 1968 |
Sodium-potassium-activated adenosine triphosphatase of brain microsomes: modification of sodium inhibition by diphenylhydantoins.
Topics: Adenosine Triphosphatases; Animals; Brain; Cats; Drug Synergism; Enzyme Activation; Enzyme Repression; Hydantoins; In Vitro Techniques; Magnesium; Microsomes; Phenols; Phenytoin; Potassium; Rats; Sodium | 1972 |
Effects of anticonvulsant drugs on nerve terminals.
Topics: Animals; Cats; Evoked Potentials; Hydantoins; Neuromuscular Junction; Phenytoin; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission; Time Factors | 1969 |
[Hydantoins and neurologic complications].
Topics: Adolescent; Brain Diseases; Cerebrospinal Fluid Proteins; Drug Hypersensitivity; Epilepsy; Humans; Hydantoins; Male; Mesencephalon; Oculomotor Nerve; Ophthalmoplegia; Peripheral Nervous System Diseases; Phenytoin; Reflex, Abnormal; Spinal Puncture; Trochlear Nerve; Vestibular Function Tests | 1973 |
Infrared studies of hydantoin and its derivatives.
Topics: Hydantoins; Infrared Rays; Phenytoin; Spectrophotometry | 1967 |
Increased susceptibility of mice to seizures after some anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Bemegride; Central Nervous System Stimulants; Drug Synergism; Electroshock; Ethionine; Female; Hydantoins; Male; Methods; Mice; Oxazines; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Rats; Seizures; Trimethadione | 1967 |
[Thin-layer chromatographic identification of some urea- and hydantoin-derivatives].
Topics: Anticonvulsants; Barbiturates; Bromides; Chromatography, Thin Layer; Hydantoins; Hypnotics and Sedatives; Meprobamate; Muscles; Phenytoin; Urea; Valerates | 1969 |
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature | 1970 |
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea | 1970 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
Effect of several anticonvulsant drugs and procainamide against ouabain-induced cardiac arrhythmias in rabbits.
Topics: Animals; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Hydantoins; Male; Ouabain; Phenytoin; Procainamide; Rabbits | 1972 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Phenobarbital; Phenytoin; Thiazines | 1971 |
Activating effect of diphenylthiohydantoin on spinal motoneurones.
Topics: Action Potentials; Animals; Cats; Decerebrate State; Dendrites; Electric Conductivity; Electric Stimulation; Hydantoins; In Vitro Techniques; Membranes; Microelectrodes; Motor Neurons; Phenytoin; Reflex, Monosynaptic; Spinal Nerves; Synapses; Thiohydantoins; Time Factors | 1974 |
The effects of diphenylthiohydantoin on the membrane potentials of rat sensory nerve fibre bundles.
Topics: Animals; Calcium; Electric Conductivity; Electric Stimulation; Electrodes; Hydantoins; In Vitro Techniques; Membrane Potentials; Neurons; Phenytoin; Potassium; Rats; Sodium; Solutions; Thiohydantoins | 1974 |
Comparative embryotoxicity of diphenyldantoin and some of its metabolites in mice.
Topics: Abnormalities, Drug-Induced; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Fetus; Gestational Age; Hydantoins; Mice; Phenytoin; Pregnancy | 1974 |
[Leukaemia following hydantoin treatment].
Topics: Aged; Female; Humans; Hydantoins; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenytoin; Seizures | 1973 |
[Malignant lymphoma or hydantoin lymphadenopathy? (author's transl)].
Topics: Diagnosis, Differential; Female; Hodgkin Disease; Humans; Hydantoins; Lymphatic Diseases; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Middle Aged; Phenytoin; Time Factors | 1973 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Identification of phenylthiohydantoins of amino acids by thin-layer chromatography.
Topics: Amino Acids; Chromatography, Thin Layer; Hydantoins; Indicators and Reagents; Phenytoin | 1973 |
Clinical implications of certain aspects of diphenylhydantoin metabolism.
Topics: Enzyme Induction; Humans; Hydantoins; Kidney; Liver; Liver Diseases; Male; Phenytoin; Protein Binding; Saliva; Serum Albumin | 1973 |
A comparison of the cardiovascular effects of diphenylthiohydantoin and diphenylhydantoin.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cats; Dose-Response Relationship, Drug; Electrocardiography; Heart; Heart Rate; Heart Ventricles; Hydantoins; Phenytoin | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)].
Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene | 1973 |
Correlation of acute diphenylhydantoin intoxication with plasma levels and metabolite excretion.
Topics: Age Factors; Child, Preschool; Chromatography, Gas; Humans; Hydantoins; Hydroxylation; Liver; Male; Phenytoin; Poisoning; Unconsciousness | 1973 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors | 1974 |
Detection of sub-nanomole amounts of phenylthiohydantoins of amino acids.
Topics: Amino Acids; Chromatography, Thin Layer; Hydantoins; Iodine; Microchemistry; Phenytoin; Thiohydantoins; Thiones; Ultraviolet Rays | 1974 |
Activation by diphenylthiohydantoin of inhibitory influences on spinal motor activity.
Topics: Animals; Cats; Decerebrate State; Electric Stimulation; Hydantoins; Motor Activity; Peripheral Nerves; Phenytoin; Reflex, Monosynaptic; Spine; Thiohydantoins | 1974 |
The in vitro inhibition of insulin secretion by diphenylhydantoin.
Topics: Animals; Anticonvulsants; Buffers; Glucose; Hydantoins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Methacholine Compounds; Ouabain; Pancreas; Pentobarbital; Phenytoin; Potassium; Rats; Tolbutamide | 1970 |
Oral bilateral symmetrical fibromas. Report of a case.
Topics: Adult; Ear Deformities, Acquired; Epilepsy, Tonic-Clonic; Fibroma; Humans; Hydantoins; Intellectual Disability; Male; Maxillary Neoplasms; Phenytoin; Prognathism | 1966 |
The development of Hodgkin's disease and lymphoma during anticonvulsant therapy.
Topics: Adult; Aged; Anticonvulsants; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Female; Hodgkin Disease; Humans; Hydantoins; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Phenytoin | 1966 |
Use of anticonvulsive drugs in the treatment of recurrent cardiac arrhythmias.
Topics: Adult; Aged; Atrial Fibrillation; Digitalis Glycosides; Electrocardiography; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Hydantoins; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal | 1966 |
Hydantoin-induced pseudo-pseudolymphoma.
Topics: Epilepsy, Tonic-Clonic; Hodgkin Disease; Humans; Hydantoins; Lymph Nodes; Lymphadenitis; Lymphatic Diseases; Male; Middle Aged; Phenobarbital; Phenytoin | 1968 |
Relationship between paroxysmal atrial tachycardia and paroxysmal cerebral discharges.
Topics: Anticonvulsants; Child, Preschool; Electrocardiography; Electroencephalography; Epilepsy; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Tachycardia; Tachycardia, Paroxysmal | 1972 |
Influence of certain anticonvulsants on the concentration of -aminobutyric acid in the cerebral hemispheres of mice.
Topics: Aminobutyrates; Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Drug Antagonism; Drug Interactions; Hydantoins; Isoniazid; Male; Mice; Phenobarbital; Phenytoin; Primidone; Stimulation, Chemical | 1972 |
Immunological abnormalities and hydantoins.
Topics: Adult; Agammaglobulinemia; Antigens; Epilepsy; Female; Humans; Hydantoins; Immunity, Cellular; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Male; Middle Aged; Nitrobenzenes; Phenytoin; Skin Tests | 1972 |
Determination of hydantoins in pharmaceutical preparations by gas chromatography.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gas; Hydantoins; Methods; Phenytoin; Tablets | 1969 |
[New drugs used in arrhythmia].
Topics: Arrhythmias, Cardiac; Cardiac Glycosides; Female; Humans; Hydantoins; Lidocaine; Male; Middle Aged; Myocarditis; Phenytoin; Propranolol; Tachycardia, Paroxysmal | 1969 |
Quantitative assay of 5,5-diphenylhydantoin (Dilantin) and 5-(p-hydroxyphenyl)-5-phenylhydantoin by gas-liquid chromatography.
Topics: Adult; Animals; Child; Chromatography, Gas; Colorimetry; Humans; Hydantoins; Methods; Phenytoin; Solvents | 1970 |
The relationship between some anticonvulsants and tumors of the blood forming organs.
Topics: Adult; Agranulocytosis; Anticonvulsants; Female; Genetics, Medical; Humans; Hydantoins; Leukocytes; Lymphatic Diseases; Lymphocytosis; Lymphoma; Male; Oxazoles; Phenytoin | 1970 |
A new metabolite of 5,5-diphenylhydantoin (Dilantin).
Topics: Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Thin Layer; Electroshock; Hot Temperature; Hydantoins; Hydrogen-Ion Concentration; Infrared Rays; Light; Mice; Models, Structural; Phenytoin; Rotation; Seizures; Spectrophotometry; Ultraviolet Rays | 1970 |
Phenytoin tolerance tests.
Topics: Administration, Oral; Adult; Arrhythmias, Cardiac; Chromatography, Thin Layer; Drug Tolerance; Epilepsy; Humans; Hydantoins; Injections, Intravenous; Intestinal Absorption; Phenytoin; Spectrophotometry | 1970 |
Pharmacologic interactions of albutoin with other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Drug Synergism; Electroshock; Hydantoins; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1970 |
Uptake and distribution of diphenylthiohydantion (DPTH).
Topics: Animals; Brain; Cats; Hydantoins; Injections, Intravenous; Kidney; Liver; Muscles; Myocardium; Phenytoin | 1970 |
The influence of folic acid on phenytoin (DPH) metabolism and the 24-hours fluctuation in urinary output of 5-(p-hydroxyphenyl)-5 phenyl-hydantoin (HPPH).
Topics: Adult; Female; Folic Acid; Humans; Hydantoins; Male; Phenytoin | 1970 |
Flash methylation and GLC of diphenylhydantoin and 5-(p-hydroxyphenyl)-5-phenylhydantoin.
Topics: Chromatography, Gas; Hydantoins; Methods; Methylation; Phenytoin | 1971 |
Methoxy derivatives of 5,5-diphenylhydantoin and 5-phenyl-5-benzylhydantoin.
Topics: Animals; Benzene Derivatives; Hydantoins; Methods; Phenytoin; Rats | 1968 |
Pseudolymphoma syndrome. A sensitivity to anticonvulsant drugs.
Topics: Biopsy; Blood Cell Count; Blood Chemical Analysis; Chlordiazepoxide; Drug Hypersensitivity; Female; Humans; Hydantoins; Hydrochlorothiazide; Lymphoma; Middle Aged; Phenobarbital; Phenytoin; Primidone; Seizures | 1968 |
Substitution in the hydantoin ring. VII. N-3-Propionic acid and its ethyl ester and N-3-(2-cyanoethyl) derivatives.
Topics: Alkylation; Animals; Drug Synergism; Electroshock; Hexobarbital; Hydantoins; Infrared Rays; Magnetic Resonance Spectroscopy; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Propionates; Spectrum Analysis; Ultraviolet Rays | 1968 |
[Pharmacologic properties of partially purified glutamic acid decarboxylase (L-glutamate-1-carboxylyase, E.C. 4.1.1.15) from calf cerebral cortex].
Topics: Animals; Antidepressive Agents; Barbiturates; Carboxy-Lyases; Cattle; Cerebral Cortex; Chemical Phenomena; Chemistry; Chlorpromazine; Codeine; Glutamates; Hydantoins; Imipramine; Lysergic Acid Diethylamide; Phenethylamines; Phenytoin; Primidone; Psilocybin; Pyrrolidines; Spectrophotometry | 1968 |
Thin-layer chromatography of anticonvulsant drugs.
Topics: Anticonvulsants; Chromatography, Thin Layer; Epilepsy; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Solvents; Time Factors | 1969 |
Gas chromatographic analysis for anticonvulsant drugs in biologic fluids.
Topics: Anticonvulsants; Chromatography, Gas; Equipment and Supplies; Humans; Hydantoins; Methods; Phenobarbital; Phenytoin; Primidone; Time Factors | 1969 |
[Myasthenic syndrome as a rare complication of hydantoin treatment].
Topics: Adult; Blood Sedimentation; Curare; Edrophonium; Electrocardiography; Electromyography; Epilepsy; Female; Humans; Hydantoins; Myasthenia Gravis; Phenytoin | 1965 |
The anticonvulsant activity of 3-ethoxycarbonyl-5,5-diphenylhydantoin (P-6127) in animals.
Topics: Animals; Cats; Electroencephalography; Hydantoins; Mice; Phenytoin; Rats; Seizures | 1965 |
Drug effects on the spontaneous electrical activity of the squid giant axon.
Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione | 1967 |
Fetal hydantoin syndrome and malignancy.
Topics: Brain Neoplasms; Female; Fetal Alcohol Spectrum Disorders; Humans; Hydantoins; Infant, Newborn; Neuroblastoma; Phenytoin; Pregnancy | 1984 |
[Synthesis of benzylidene derivatives of 3-o, 3-m and 3-p-chlorophenylhydantoin and the study of their anticonvulsant action].
Topics: Animals; Benzylidene Compounds; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Hydantoins; Male; Mice; Phenytoin; Seizures | 1984 |
[Relations to the use of antiepileptics by the pregnant woman to the development of congenital abnormalities in her child].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Epilepsy; Female; Humans; Hydantoins; Infant, Newborn; Phenytoin; Pregnancy; Pregnancy Complications; Risk | 1983 |
Synthesis of 3-dialkylaminopropyl-2-thiohydant derivatives as potential antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Electrocardiography; Female; Hydantoins; Lethal Dose 50; Male; Mice; Phenytoin; Thiohydantoins | 1983 |
Comparative actions of phenytoin and other anticonvulsant drugs on potassium- and veratridine-stimulated calcium uptake in synaptosomes.
Topics: Animals; Anticonvulsants; Brain; Calcium; Hydantoins; In Vitro Techniques; Manganese; Phenytoin; Potassium; Rats; Synaptosomes; Tetrodotoxin; Veratridine | 1982 |
The synthesis of some 11C-labelled antiepileptic drugs with potential utility as radiopharmaceuticals: hydantoins and barbiturates.
Topics: Anticonvulsants; Barbital; Barbiturates; Carbon Radioisotopes; Hydantoins; Isotope Labeling; Mephenytoin; Phenobarbital; Phenytoin | 1981 |
Effect of diphenylhydantoin, granatane-3-spiro-5'-hydantoin and leptazol on mouse brain glutamate dehydrogenase, urea and ammonia levels in brain.
Topics: Ammonia; Animals; Brain; Drug Interactions; Glutamate Dehydrogenase; Hydantoins; Mice; Mice, Inbred ICR; Pentylenetetrazole; Phenytoin; Urea | 1981 |
Fetal hydantoin syndrome, neuroblastoma, and hemorrhagic disease in a neonate.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Epilepsy; Female; Humans; Hydantoins; Infant, Newborn; Male; Maternal-Fetal Exchange; Neuroblastoma; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Syndrome; Vitamin K Deficiency Bleeding | 1980 |
Structural and electronic conditions for anticonvulsant activity of bicyclic hydantoin derivatives.
Topics: Anticonvulsants; Crystallography, X-Ray; Electroshock; Hydantoins; Pentylenetetrazole; Phenytoin; Stereoisomerism; Structure-Activity Relationship | 1995 |
Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat.
Topics: Alkylation; Animals; Barbital; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydantoins; Liver; Male; Organ Size; Oxazines; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344 | 1994 |
Changes in the metabolism of three model substrates catalysed by different P450 isozymes when administered as a cocktail to the carbon tetrachloride-intoxicated rat.
Topics: Animals; Biotransformation; Caffeine; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme System; Hydantoins; Injections, Intravenous; Isoenzymes; Lidocaine; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Theophylline | 1995 |
Induction of lymphoproliferative popliteal lymph node reaction by hydantoin derivatives: structure-activity relationships.
Topics: Animals; Extremities; Female; Hydantoins; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phenytoin | 1995 |
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured | 2001 |
Experimental production of gingival hyperplasia in ferrets given epanutin (sodium diphenyl hydantoinate).
Topics: Animals; Biphenyl Compounds; Disease; Ferrets; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Phenytoin; Sodium | 1952 |
Cross-sensitivity to diphenylhydantoin sodium and to phenobarbital.
Topics: Barbiturates; Drug Eruptions; Humans; Hydantoins; Phenobarbital; Phenytoin; Sodium | 1953 |
The combined anticonvulsant activity and toxicity of dilantin and N-methyl-5-phenylsuccinimide.
Topics: Anticonvulsants; Hydantoins; Phenytoin; Seizures | 1953 |
[Analysis of diphenylhydantoin in electroshock and metrazol shock].
Topics: Convulsive Therapy; Electroshock; Hydantoins; Pentylenetetrazole; Phenytoin; Shock | 1952 |
[Experiences with comital and comital-L].
Topics: Barbiturates; Drug Combinations; Epilepsy; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin | 1951 |
[The formation of diphenylhydantil].
Topics: Hydantoins; Phenytoin | 1952 |
[Considerations on certain cases of gingival hypertrophy due to sodium diphenylhydantoin].
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hypertrophy; Hydantoins; Hyperplasia; Hypertrophy; Phenytoin; Sodium | 1952 |
[Injurious effects of diphenylhydantoin in children].
Topics: Hydantoins; Phenytoin | 1953 |
Nuvarone (3-methyl-5, phenylhydantoin) in the treatment of epilepsy.
Topics: Epilepsy; Hydantoins; Phenytoin | 1953 |
Diphenylhydantoin, adrenal function and epilepsy.
Topics: Adrenal Cortex; Epilepsy; Hydantoins; Phenytoin | 1953 |
[Clinical experiences with diphenylhydantoins in the treatment of epilepsy, with special reference to lepitoin].
Topics: Epilepsy; Hydantoins; Phenytoin | 1953 |
Dilantin gingival hyperplasia; report of a case.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phenytoin | 1953 |
[Significance of the attack point of diphenylhydantoin, phenobarbital and the acylureas for our comprehension of the physiopathological mechanism of epilepsy].
Topics: Animals; Barbiturates; Behavior, Animal; Comprehension; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Social Behavior; Urea | 1953 |
ADRENAL glands and gingival hyperplasia due to phenytoin sodium.
Topics: Adrenal Glands; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin | 1953 |
[A case of toxic manifestations of diphenylhydantoin sodium].
Topics: Humans; Hydantoins; Phenytoin; Sodium | 1953 |
[Effect of iodine on organic compounds; diphenylhydantoin and diphenylthiohydantoin].
Topics: Hydantoins; Iodides; Iodine; Organic Chemicals; Phenytoin; Thiohydantoins | 1953 |
[Therapy of trigeminal neuralgia with diphenylhydantoin].
Topics: Humans; Hydantoins; Medicine; Phenytoin; Psychoneuroimmunology; Psychophysiologic Disorders; Psychosomatic Medicine; Trigeminal Neuralgia | 1954 |
[Further study on paradental changes caused by diphenylhydantoin sodium].
Topics: Disease; Epilepsy; Hydantoins; Hyperplasia; Hypertrophy; Periodontal Diseases; Periodontium; Phenytoin; Sodium | 1953 |
Electroencephalographic studies, induced seizures, and their modification by phenobarbital, dilantin, and phenurone, in the salamanders, Triturus viridescens and Ambystoma tigrinum.
Topics: Ambystoma; Animals; Anticonvulsants; Barbiturates; Benzeneacetamides; Electroencephalography; Humans; Hydantoins; Notophthalmus viridescens; Phenobarbital; Phenytoin; Seizures; Urea; Urodela | 1954 |
The effect of diphenylhydantoin sodium (dilantin), procaine hydrochloride, procaine amide hydrochloride, and quinidine hydrochloride upon ouabain-induced ventricular tachycardia in unanesthetized dogs.
Topics: Animals; Dogs; Hydantoins; Ouabain; Phenytoin; Procainamide; Procaine; Quinidine; Sodium; Tachycardia; Tachycardia, Ventricular | 1954 |
The effects of continued administration of 5:5-diphenythydantoin (dilantin) sodium on the adrenal glands in mice.
Topics: Adrenal Glands; Animals; Hydantoins; Ions; Mice; Pharmaceutical Preparations; Phenytoin; Sodium; Sodium, Dietary | 1954 |
A failure to produce enlargement of gingiva in rats by using dilantin sodium.
Topics: Animals; Gingiva; Hydantoins; Hypertrophy; Phenytoin; Rats; Sodium | 1954 |
Megaloblastic anaemia due to phenytoin sodium.
Topics: Anemia; Anemia, Megaloblastic; Epilepsy; Humans; Hydantoins; Phenytoin | 1954 |
Megaloblastic anaemia due to phenytoin sodium.
Topics: Anemia; Anemia, Megaloblastic; Epilepsy; Humans; Hydantoins; Phenytoin | 1954 |
[Diphenylhydantoin poisoning characterized with diffuse neurological signs and peculiar cerebrospinal fluid modifications].
Topics: Cardiovascular Agents; Central Nervous System Depressants; Cerebrospinal Fluid; Databases, Genetic; Humans; Hydantoins; Nervous System; Phenytoin; Physical Examination | 1954 |
[Skin and lymph node accidents during treatment with diphenylhydantoin and phenacetylurea].
Topics: Accidents; Anticonvulsants; Drug Eruptions; Humans; Hydantoins; Lymph Nodes; Phenytoin; Skin | 1954 |
[Effect of diphenylhydantoin on pituitary-adrenocortical system].
Topics: Adrenal Cortex; Hydantoins; Phenytoin; Pituitary Diseases; Pituitary Gland | 1954 |
Methaemoglobinaemia in the newborn probably due to phenytoin excreted in human milk.
Topics: Child; Humans; Hydantoins; Infant; Infant, Newborn; Methemoglobinemia; Milk, Human; Phenytoin | 1954 |
[Chlorpromazine potentiation of the anticonvulsant effect of diphenylhydantoin].
Topics: Anticonvulsants; Chlorpromazine; Hydantoins; Phenytoin | 1954 |
[Hyperplasia of gingiva caused by prolonged treatment with dilantin].
Topics: Disease; Gingiva; Gingival Diseases; Hydantoins; Hyperplasia; Phenytoin | 1954 |
[Adrenocortical function, diphenylhydantoin and epilepsy].
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Epilepsy; Humans; Hydantoins; Phenytoin | 1954 |
[On the diphenylhydantoin therapy of trigeminal neuralgia].
Topics: Humans; Hydantoins; Phenytoin; Trigeminal Neuralgia | 1955 |
Hypertrichosis occurring in association with dilantin therapy.
Topics: Child; Epilepsy; Hair; Hair Diseases; Humans; Hydantoins; Hypertrichosis; Infant; Phenytoin | 1955 |
Effect of diphenylhydantoin on electrolytes and radiosodium turnover in brain and other tissues of normal, hyponatremic and postictal rats.
Topics: Animals; Anions; Brain; Electrolytes; Hydantoins; Ions; Phenytoin; Rats; Sodium | 1955 |
Effects of sodium diphenylhydantoinate upon isolated small intestine of the rabbit.
Topics: Animals; Hydantoins; Intestine, Small; Intestines; Phenytoin; Rabbits | 1955 |
Diphenylhydantoin (dilantin) sodium used parenterally in control of convulsions; a five-year report.
Topics: Anions; Hydantoins; Ions; Phenytoin; Seizures; Sodium; Sodium, Dietary | 1956 |
[Diphenylhydantoin poisoning, with hearing disorder as a manifestation].
Topics: Cardiovascular Agents; Hearing; Hearing Disorders; Hearing Tests; Humans; Hydantoins; Phenytoin | 1955 |
Diphenylhydantoin sensitivity; report of fatal case with hepatitis and exfoliative dermatitis.
Topics: Dermatitis, Exfoliative; Hepatitis; Hydantoins; Phenytoin; Viral Vaccines | 1956 |
Speculations regarding the nature of gingival hyperplasia due to diphenylhydantoin-sodium.
Topics: Disease; Epilepsy; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phenytoin; Sodium | 1956 |
The formulation of an oral suspension of diphenylhydantoin.
Topics: Chemistry, Pharmaceutical; Humans; Hydantoins; Phenytoin; Suspensions | 1956 |
Fatal aplastic anemia after therapy with nuvarone (3-methyl-5-phenylhydantoin).
Topics: Anemia; Anemia, Aplastic; Humans; Hydantoins; Phenytoin | 1956 |
A method for the simultaneous determination of phenobarbital and diphenylhydantoin in blood.
Topics: Barbiturates; Blood; Humans; Hydantoins; Phenobarbital; Phenytoin | 1956 |
[Hirsutism and 5,5 diphenylhydantoin].
Topics: Hair; Hirsutism; Humans; Hydantoins; Phenytoin | 1955 |
Rare complication of phenytoin sodium treatment.
Topics: Hemiplegia; Humans; Hydantoins; Phenytoin | 1956 |
Studies on 5, 5'-diphenylhydantoin (dilantin) in animals and man.
Topics: Hydantoins; Phenytoin | 1956 |
Diphenylhydantoin and brain-levels and 5-hydroxytryptamine.
Topics: Biochemical Phenomena; Brain; Hydantoins; Phenytoin; Serotonin | 1956 |
Treatment of epilepsy with diphenylhydantoin sodium (dilantin sodium).
Topics: Epilepsy; Humans; Hydantoins; Phenytoin; Sodium | 1956 |
Postictal recovery in normal and diphenylhydantoin (dilantin)-treated mice.
Topics: Animals; Hydantoins; Mice; Phenytoin; Physiological Phenomena; Seizures | 1956 |
[Effect of diphenylhydantoin on the vestibulo-cerebellar system].
Topics: Cerebellum; Humans; Hydantoins; Nerve Tissue; Phenytoin; Vestibule, Labyrinth | 1956 |
Antihistaminic therapy for gingival hyperplasia due to dilantin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phenytoin | 1957 |
Megaloblastic anaemia in patients treated with diphenylhydantoin and primidone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenytoin; Primidone | 1957 |
[Acute diphenylhydantoin poisoning].
Topics: Cardiovascular Agents; Humans; Hydantoins; Phenytoin | 1957 |
Metabolism of 5 : 5-diphenylhydantoin in the rabbit.
Topics: Animals; Hydantoins; Phenytoin; Rabbits | 1957 |
Diphenylhydantoin in tic douloureux and atypical facial pain.
Topics: Disease; Face; Facial Pain; Humans; Hydantoins; Phenytoin; Trigeminal Neuralgia | 1957 |
Megaloblastic anaemia occurring during treatment of epilepsy with phenytoin sodium, primidone and phenobarbitone.
Topics: Anemia; Anemia, Megaloblastic; Anticonvulsants; Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone | 1957 |
Effects of diphenylhydantoin on synaptic transmission in cat spinal cord and stellate ganglion.
Topics: Animals; Cats; Hydantoins; Phenytoin; Spinal Cord; Stellate Ganglion; Synapses; Synaptic Transmission | 1957 |
Biochemical studies on acute inflammation. II. The effect of dilantin.
Topics: Disease; Gingivitis; Hydantoins; Inflammation; Palate; Phenytoin | 1957 |
Ineffectiveness of antihistamine therapy for gingival hyperplasia due to diphenylhydantoin sodium.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phenytoin; Sodium | 1957 |
Acute diphenylhydantoin intoxication: report of two cases.
Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Hydantoins; Phenytoin; Psychoses, Substance-Induced | 1957 |
The chromatographic separation and determination of diphenylhydantoin and phenobarbital.
Topics: Chromatography; Humans; Hydantoins; Phenobarbital; Phenytoin; Rare Diseases; Retinal Degeneration; Retinal Detachment | 1958 |
Use of parenteral diphenylhydantoin (dilantin) sodium in control of status epilepticus.
Topics: Epilepsy; Hydantoins; Ions; Phenytoin; Sodium; Sodium, Dietary; Status Epilepticus | 1958 |
Dilantin in the treatment of trigeminal neuralgia.
Topics: Humans; Hydantoins; Phenytoin; Trigeminal Neuralgia | 1958 |
Effect of diphenylhydantoin on peripheral nerve.
Topics: Humans; Hydantoins; Peripheral Nerves; Phenytoin | 1958 |
Cerebellar lesions after parenteral dilantin administration.
Topics: Cerebellum; Humans; Hydantoins; Pharmaceutical Preparations; Phenytoin | 1958 |
The use of diphenylhydantoin (dilantin) sodium in the treatment of ventricular tachycardia.
Topics: Hydantoins; Ions; Phenytoin; Sodium; Sodium, Dietary; Tachycardia; Tachycardia, Ventricular | 1958 |
[Effect of diphenylhydantoin on convulsion excitability of the cerebral cortex].
Topics: Cerebral Cortex; Humans; Hydantoins; Phenytoin; Psychomotor Agitation; Seizures | 1957 |
Acceleration of gingival wound healing in non-epileptic patients receiving diphenylhydantoin sodium (dilantin, epanutin).
Topics: Acceleration; Gingiva; Humans; Hydantoins; Phenytoin; Seizures; Sodium; Wound Healing | 1958 |
[Relation between chemical structure and local anesthetic action: tertiary alkylamine derivatives of diphenylhydantoin].
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Hydantoins; Phenytoin | 1958 |
Studies on the absorption, distribution, fate and excretion of 4-C14-labeled diphenylhydantoin.
Topics: Biological Transport; Body Fluids; Hydantoins; Phenytoin | 1958 |
Effect of dilantin sodium on tensile strength of healing wounds.
Topics: Humans; Hydantoins; Phenytoin; Sodium; Tensile Strength; Wound Healing; Wounds and Injuries | 1958 |
Diphenylhydantoin and phenobarbital in serum in patients with epilepsy.
Topics: Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin | 1958 |
Antihistamine therapy for gingival hyperplasia due to diphenylhydantoin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phenytoin | 1958 |
[Spectrophotometric analysis of mixtures of phenobarbitone & phenytoin].
Topics: Hydantoins; Phenobarbital; Phenytoin; Spectrophotometry | 1958 |
[Dilantin therapy of epilepsy in children].
Topics: Child; Epilepsy; Humans; Hydantoins; Infant; Phenytoin | 1957 |
[Pharmacological research on some tertiary amine derivatives of diphenylhydantoin].
Topics: Amines; Hydantoins; Phenytoin; Research | 1958 |
[Relation between chemical structure and local anesthetic activity; the hydrolysis products of 5, 5-bis(2-phenylethyl)-1-(2-diethylaminoethyl)-barbituric acid and of 3-(2-diethylaminoethyl)-5, 5-diphenylhydantoin].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Local; Anesthetics; Anesthetics, Local; Barbiturates; Hydantoins; Hydrolysis; Phenytoin | 1958 |
Anticonvulsant drug combinations: diphenylhydantoin combined with other antiepileptics.
Topics: Anticonvulsants; Drug Combinations; Humans; Hydantoins; Phenytoin | 1958 |
Antihistamines and diphenylhydantoin-induced gingival hyperplasia.
Topics: Anti-Allergic Agents; Gingiva; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antagonists; Hydantoins; Phenytoin | 1958 |
[Fifteen years of trial therapy of essential trigeminal neuralgia: the place of diphenylhydantoin and its derivatives].
Topics: Humans; Hydantoins; Phenytoin; Trigeminal Neuralgia | 1958 |
The anticonvulsant actions of methazolamide (a carbonic anhydrase inhibitor) and diphenylhydantoin.
Topics: Acetazolamide; Anticonvulsants; Carbonic Anhydrase Inhibitors; Hydantoins; Methazolamide; Phenytoin | 1958 |
[The influence of neurotropic substances (atropine, adiphenine, tetraethylammonium, diphenylhydantoin, ephedrine) on vitamin B1 metabolism in peptic ulcer].
Topics: Atropine; Diphenylacetic Acids; Ephedrine; Humans; Hydantoins; Parasympatholytics; Peptic Ulcer; Phenytoin; Tetraethylammonium; Thiamine | 1958 |
The response to diphenylhydantoin of the neurosecretory substance in the mouse.
Topics: Animals; Hydantoins; Mice; Nervous System; Nervous System Physiological Phenomena; Phenytoin | 1958 |
Intravenous phenytoin sodium in continuous convulsions in children.
Topics: Child; Humans; Hydantoins; Infant; Phenytoin; Seizures | 1958 |
Diphenylhydantoin (dilantin) after 20 years; a review with re-emphasis by treatment of 84 patients.
Topics: Hydantoins; Phenytoin | 1959 |
Phenytoin toxicity with associated meningeal reaction.
Topics: Cerebrospinal Fluid; Disease; Humans; Hydantoins; Meninges; Phenytoin | 1958 |
Effects of antihistaminic therapy on diphenylhydantoin sodium (dilantin) gingival hyperplasia.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phenytoin; Sodium | 1959 |
Anticonvulsant effect of dilantin sodium by intravenous administration in mice.
Topics: Administration, Intravenous; Animals; Anticonvulsants; Hydantoins; Mice; Phenytoin; Seizures; Sodium | 1959 |
Effects of diphenylhydantoin upon adrenal cortical function in man.
Topics: Adrenal Cortex; Humans; Hydantoins; Phenytoin; Seizures | 1959 |
Congestive heart failure caused by sensitivity to diphenylhydantoin (diiantin sodium).
Topics: Heart Failure; Humans; Hydantoins; Hypersensitivity; Immune System Diseases; Phenytoin; Sodium; Sodium, Dietary | 1959 |
Abducens nerve palsy in dilantin intoxication.
Topics: Abducens Nerve; Abducens Nerve Diseases; Cardiovascular Agents; Hydantoins; Paralysis; Phenytoin | 1959 |
[Localized ecchymotic purpura caused by thiouracil and diphenylhydantoin].
Topics: Hydantoins; Phenytoin; Purpura; Thiouracil | 1960 |
The toxic effects of diphenylhydantoin: a report of 23 cases.
Topics: Hydantoins; Phenytoin | 1961 |
Dilantin in the treatment of lightning pains.
Topics: Humans; Hydantoins; Lightning; Pain; Phenytoin; Tabes Dorsalis | 1961 |
The effect of sodium dilantin administration upon the chemistry of the skin.
Topics: Hydantoins; Phenytoin; Skin; Sodium | 1960 |
[Diphenylhydantoin exanthema in the form of an infectious mononucleosis].
Topics: Exanthema; Humans; Hydantoins; Infectious Mononucleosis; Phenytoin | 1960 |
Dilantin toxicity. A clinical and electroence-phalographic study.
Topics: Epilepsy; Hydantoins; Phenytoin | 1961 |
Syndrome simulatingqymphosarcoma induced by diphenylhydantoin sodium.
Topics: Disease; Humans; Hydantoins; Lymph Nodes; Lymphatic Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Phenytoin; Sodium | 1961 |
The effect of diphenylhydantoin (Dilantin) sodium on atrial flutter and fibrillation provoked by focal application of a conitine or delphinine.
Topics: Alkaloids; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Cardiac Conduction System Disease; Heart Conduction System; Humans; Hydantoins; Phenytoin; Sodium | 1960 |
Effect of dilantin sodium analogues on cell proliferation in tissue culture.
Topics: Cell Proliferation; Hydantoins; Inorganic Chemicals; Organic Chemicals; Phenytoin; Sodium; Tissue Culture Techniques | 1961 |
Leukopenia with diphenylhydantoin.
Topics: Humans; Hydantoins; Leukopenia; Phenytoin | 1961 |
Study of the effects of diphenylhydantoin sodium on the lungs.
Topics: Hydantoins; Lung; Phenytoin; Sodium | 1961 |
Studies on the metabolism of diphenylhydantoin (Dilantin).
Topics: Hydantoins; Phenytoin | 1961 |
The lack of pulmonary fibrosis in patients receiving diphenylhydantoin.
Topics: Hydantoins; Phenytoin; Pulmonary Fibrosis | 1960 |
Megaloblastic anemia due to dilantin therapy.
Topics: Anemia; Anemia, Megaloblastic; Hydantoins; Phenytoin | 1961 |
[Status of epilepsy in children: clinical experience with sodium diphenylhydantoin by parenteral route].
Topics: Child; Epilepsy; Hydantoins; Infant; Phenytoin; Sodium | 1961 |
The metabolic fate of diphenylhydantoin in the dog, rat and man.
Topics: Animals; Dogs; Hydantoins; Phenytoin; Rats | 1960 |
Acute dilantin poisoning.
Topics: Hydantoins; Phenytoin | 1961 |
Diphenylhydantoin sodium (Dilantin) intoxication in children.
Topics: Hydantoins; Phenytoin; Sodium | 1961 |
[Comparative effects of phenytoin and of a homologue on the adreno-pituitary system].
Topics: Adrenal Cortex; Hydantoins; Phenytoin; Pituitary Diseases; Pituitary Gland; Pituitary Gland, Anterior | 1959 |
[On the preparation and stability of phenytoin solutions for injection].
Topics: Hydantoins; Injections; Phenytoin; Solutions | 1960 |
[Favorable action of diphenylhydantoin on the resistance of the rat to drowning].
Topics: Animals; Biochemical Phenomena; Drowning; Hydantoins; Phenytoin; Rats | 1959 |
[On the hypothermal properties of diphenylhydantoin].
Topics: Body Temperature; Hydantoins; Phenytoin | 1959 |
[On the effect of diphenylhydantoin in painful conditions].
Topics: Hydantoins; Pain Management; Phenytoin; Somatoform Disorders | 1960 |
5, 5-Diphenylhydantoin (dilantin) blood levels after oral or intravenous dosage in man.
Topics: Humans; Hydantoins; Phenytoin | 1960 |
Granulocytopenia after treatment with phenytoin sodium.
Topics: Agranulocytosis; Humans; Hydantoins; Phenytoin | 1960 |
Aspects of the pharmacology of phenytoin (dilantin) and phenobarbital relevant to their dosage in the treatment of epilepsy.
Topics: Epilepsy; Humans; Hydantoins; Phenobarbital; Phenytoin | 1960 |
[Determination of the content of diphenylhydantoin in tablets].
Topics: Hydantoins; Phenytoin; Tablets | 1960 |
Differential effects of phenobarbital, pentobarbital and diphenylhydantoin on motor cortical and reticular thresholds in the rhesus monkey.
Topics: Animals; Cerebral Cortex; Humans; Hydantoins; Macaca mulatta; Mesencephalon; Pentobarbital; Phenobarbital; Phenytoin | 1961 |
Generalized lymphadenopathy and hepatosplenomegaly induced by diphenylhydantoin.
Topics: Disease; Hepatomegaly; Humans; Hydantoins; Lymph Nodes; Lymphatic Diseases; Phenytoin; Splenomegaly | 1961 |
Connective tissue. VI. Dermal lipid response to diphenylhydantoin.
Topics: Connective Tissue; Hydantoins; Lipids; Phenytoin; Skin | 1962 |
Failure of diphenylhydantoin in preventing barbiturate withdrawal convulsions in the dog.
Topics: Animals; Barbiturates; Dogs; Hydantoins; Phenytoin; Seizures; Substance Withdrawal Syndrome | 1962 |
[Use of parenteral dilantin sodium in control of neurosurgical convulsive seizure].
Topics: Epilepsy; Hydantoins; Neurosurgery; Neurosurgical Procedures; Phenytoin; Seizures; Sodium | 1962 |
Effect of dilantin sodium on various cell lines in tissue culture.
Topics: Cell Biology; Cell Line; Cytodiagnosis; Humans; Hydantoins; Immunologic Tests; Phenytoin; Research Design; Sodium | 1961 |
Agranulocytosis after diphenylhydantoin and chlorothiazide therapy. A case report and discussion of the evidence for the primary role of diphenylhydantoin.
Topics: Agranulocytosis; Chlorothiazide; Hydantoins; Phenytoin | 1961 |
The effect of dilantin sodium on connective tissue generation in polyvinyl sponge implants.
Topics: Connective Tissue; Hydantoins; Phenytoin; Polyvinyls; Prostheses and Implants; Sodium | 1962 |
Antagonism of pentobarbitone anaesthesia in hamsters by 5,5-diphenylhydantoin modified by salicylate.
Topics: Anesthesia; Anesthesiology; Hydantoins; Pentobarbital; Phenytoin; Salicylates | 1962 |
Determination of plasma and cerebrospinal fluid levels of dilantin in the human.
Topics: Humans; Hydantoins; Phenytoin; Plasma | 1960 |
[The effects of diphenylhydantoin on the central nervous system. Report of 2 cases].
Topics: Central Nervous System; Hydantoins; Phenytoin | 1962 |
Displacement of thyroxine from human thyroxine-binding globulin by analogues of hydantoin. Steric aspects of the thyroxinebinding site.
Topics: Anticonvulsants; Humans; Hydantoins; Imidazoles; Phenytoin; Serum Globulins; Thyroxine; Thyroxine-Binding Globulin | 1962 |
Dermal chemical response to analogues of dilantin.
Topics: Hydantoins; Phenytoin; Skin | 1963 |
Rapid diagnosis of drug-induced thrombocytopenic purpura. Report of three cases due to quinine, quinidine, and Dilantin.
Topics: Humans; Hydantoins; Phenytoin; Purpura; Purpura, Thrombocytopenic; Quinidine; Quinine; Thrombocytopenia | 1962 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology | 1963 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE USE OF ANTICONVULSANT DRUGS. REPORT OF A CASE AND REVIEW OF THE LITERATURE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Toxicology | 1963 |
A METHOD FOR EVALUATION OF PHYSIOLOGICAL AVAILABILITY OF DIPHENYL HYDANTOIN BY URINARY ANALYSIS.
Topics: Anticonvulsants; Biphenyl Compounds; Body Fluids; Hydantoins; Imidazoles; Phenytoin; Research; Urine | 1963 |
[INFLUENCE OF ANTIEPILEPTIC AGENTS ON THE K AND NA IONIC GRADIENTS OF NON-STIMULATED CEREBRAL CORTEX SLICES IN VITRO].
Topics: Anions; Anticonvulsants; Borates; Bromides; Cerebral Cortex; Guinea Pigs; Hydantoins; In Vitro Techniques; Ions; Metabolism; Pharmacology; Phenytoin; Potassium; Research; Sodium; Sodium, Dietary | 1963 |
[PSEUDOCOLLAGENOSIS OR MALIGNANT PSEUDOLYMPHOMA?INJURIOUS EFFECT OF A HYDANTOIN DERIVATIVE].
Topics: Adrenal Cortex Hormones; Biopsy; Diagnosis, Differential; Epilepsy; Erythema; Fever; Humans; Hydantoins; Lymphadenitis; Phenytoin; Pneumonia; Pseudolymphoma; Splenomegaly; Toxicology | 1964 |
[ACTION OF VARIOUS UREIDES ON K GRADIENTS OF MAMMALIAN CEREBRAL TISSUE ELECTRICALLY STIMULATED IN VITRO].
Topics: Anticonvulsants; Barbiturates; Brain; Electrophysiological Phenomena; Electrophysiology; Guinea Pigs; Hydantoins; Hypnotics and Sedatives; In Vitro Techniques; Metabolism; Pentobarbital; Pharmacology; Phenobarbital; Phenytoin; Potassium; Research; Urea | 1963 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
NOTE ON THE DETECTION OF HEXOESTROL, STILBOESTROL, DIENOESTROL AND THE P-HYDROXY METABOLITES OF PHENOBARBITONE AND PHENYTOIN IN URINE.
Topics: Chromatography; Dienestrol; Diethylstilbestrol; Estrogens; Hexestrol; Hydantoins; Phenobarbital; Phenytoin; Research; Urine | 1964 |
INVESTIGATIONS FOR PYRONIN BODIES AND FLUORESCENT ANTIBODIES IN 5:5 DIPHENYLHYDANTOIN GINGIVAL HYPERPLASIA.
Topics: Coloring Agents; Drug Therapy; Fluorescent Antibody Technique; gamma-Globulins; Gingival Hyperplasia; Humans; Hydantoins; Pathology; Periodontitis; Pharmacology; Phenytoin; Staining and Labeling; Xanthines | 1964 |
THE IN VITRO EFFECT OF 5,5'-DIPHENYLHYDANTOIN ON THE CATABOLISM OF CORTISOL BY RAT LIVER.
Topics: Hydantoins; Hydrocortisone; In Vitro Techniques; Liver; Metabolism; NAD; Pharmacology; Phenytoin; Rats; Research | 1964 |
[HYPERTROPHIC GINGIVITIS CAUSED BY HYDANTOIN].
Topics: Anticonvulsants; Drug Therapy; Gingival Hypertrophy; Gingivitis; Humans; Hydantoins; Hypertrophy; Phenytoin; Toxicology | 1964 |
[TREATMENT OF EPILEPSY WITH 3-ETHOXYCARBO-5,5-DIPHENYLHYDANTOIN (P-6127), A NEW ANTICONVULSANT].
Topics: Anticonvulsants; Ataxia; Blood Chemical Analysis; Drug Therapy; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Hyperplasia; Myoclonus; Nystagmus, Pathologic; Phenytoin; Seizures; Toxicology | 1964 |
A study of the anticonvulsant properties of phenobarbital and dilantin.
Topics: Anticonvulsants; Barbiturates; Hydantoins; Phenobarbital; Phenytoin | 1954 |
[Study of the activity and toxicity of antiepileptic drugs (phenobarbital, diphenylhydantoin, phenylethylacetylurea and 5-ethylhexahydro-5-phenylpyrimidine-4,6-dione)].
Topics: Anticonvulsants; Barbiturates; Hydantoins; Phenobarbital; Phenytoin; Urea | 1954 |
The effects of diphenylhydantoin sodium, glucose and beta-diethylaminoethyl diphenylpropylacetate hydrochloride on cyclopropane-epinephrine arrhythmias in the dog.
Topics: Animals; Arrhythmias, Cardiac; Cyclopropanes; Dogs; Epinephrine; Fatty Acids; Glucose; Hydantoins; Phenytoin; Sodium | 1955 |
Studies on anticonvulsant drug combinations: phenobarbital and diphenylhydantoin.
Topics: Anticonvulsants; Barbiturates; Drug Combinations; Hydantoins; Phenobarbital; Phenytoin | 1955 |
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases; Nephritis; Phenobarbital; Phenytoin; Poisoning; Primidone | 1955 |
Effects of diphenylhydantoin (dilantin) on adrenal cortical function; a study in nonepileptic human subjects.
Topics: Adrenal Cortex; Humans; Hydantoins; Phenytoin; Seizures | 1955 |
Megaloblastic anaemia due to phenytoin sodium.
Topics: Anemia; Anemia, Megaloblastic; Epilepsy; Hydantoins; Phenytoin; Tracheophyta | 1955 |
Observations of the depressant effects of parenterally administered dilantin on the cardiovascular system and cerebral cortex.
Topics: Cardiovascular System; Cerebral Cortex; Hydantoins; Phenytoin | 1959 |
Antihistamines in treatment of gingival hyperplasia caused by diphenylhydantoin.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antagonists; Hydantoins; Phenytoin | 1959 |
Effect of lidocaine and procaine on the electroshock seizure threshold, with a comparison of the effects of phenytoin and phenobarbital.
Topics: Convulsive Therapy; Electroconvulsive Therapy; Electroshock; Humans; Hydantoins; Lidocaine; Phenobarbital; Phenytoin; Procaine; Seizures | 1960 |
[The effects of acetazolamide and diphenylhydantoin on brain sodium and amino acid metabolism].
Topics: Acetazolamide; Amino Acids; Brain; Hydantoins; Phenytoin; Sodium | 1959 |
Effect of dilantin sodium on growth of human fibroblast-like cell cultures.
Topics: Cell Culture Techniques; Fibroblasts; Hydantoins; Phenytoin; Physiological Phenomena; Sodium; Tissue Culture Techniques | 1960 |
[Derivatives of 5,5-bis-(p-methoxyphenyl)hydantoin and of 5,5-diphenylthiohydantoin with elevated myolitic and local anesthetic activity].
Topics: Anesthesia, Local; Anesthetics; Anesthetics, Local; Hydantoins; Phenytoin; Thiohydantoins | 1960 |
The resorption of sodium dilantin-produced dermal collagen.
Topics: Administration, Cutaneous; Collagen; Humans; Hydantoins; Phenytoin; Skin; Sodium | 1962 |
[Infrequent manifestation of sensitivity to phenylhydantoin].
Topics: Automatism; Hallucinations; Humans; Hydantoins; Phenytoin | 1961 |
Effect of diphenylhydantoin on pituitary-adrenal interrelations.
Topics: Adrenal Cortex; Hydantoins; Phenytoin; Pituitary Diseases; Pituitary Gland; Pituitary Gland, Anterior | 1962 |
[Diphenylhydantoin for trigeminal neuralgia].
Topics: Humans; Hydantoins; Phenytoin; Trigeminal Neuralgia | 1961 |
Studies on the thyroxine-diphenylhydantoin interaction: effect of 5,5'-diphenylhydantoin on the displacement of L-thyroxine from thyroxine-binding globulin (TBG).
Topics: Humans; Hydantoins; Phenytoin; Serum Globulins; Thyroid Hormones; Thyroxine; Thyroxine-Binding Globulin | 1962 |
Anticonvulsant effect of nialamide and diphenylhydantoin.
Topics: Anticonvulsants; Hydantoins; Nialamide; Phenytoin; Psychopharmacology; Seizures | 1961 |
Diphenylhydantoin sensitivity. A case with exfoliative dermatitis and atypical lymphocytes in the peripheral blood.
Topics: Child; Dermatitis, Exfoliative; Drug Eruptions; Humans; Hydantoins; Infant; Leukocytes; Lymphocytes; Phenytoin | 1962 |
A comparison of the anticonvulsant actions of some phenylhydantoins and their corresponding phenylacetylureas.
Topics: Anticonvulsants; Benzeneacetamides; Hydantoins; Phenytoin; Urea | 1950 |
[Results of recent study on the combination of barbituric acid derivatives, prominal and luminal with sodium diphenylhydantoinate, and its effect in clinical use].
Topics: Barbital; Barbiturates; Hydantoins; Mephobarbital; Phenytoin | 1950 |
Effects of diphenylhydantoin sodium (dilantin sodium) and phenobarbital sodium upon ectopic ventricular tachycardia in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Barbital; Heart; Hydantoins; Myocardial Infarction; Phenobarbital; Phenytoin; Sodium; Tachycardia; Tachycardia, Ventricular; Ventricular Premature Complexes | 1950 |
Effect of dilantin and mesantoin on the giant axon of the squid.
Topics: Animals; Axons; Decapodiformes; Hydantoins; Mephenytoin; Phenytoin; Shellfish | 1951 |
What comes after dilantin?
Topics: Epilepsy; Humans; Hydantoins; Phenytoin; Psychotherapy | 1950 |
Comparative results in seizure control using phenobarbital, dilantin, and mesantoin.
Topics: Barbital; Epilepsy; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Seizures | 1950 |
[Gingival hyperplasia due to sodium diphenylhydantoinate].
Topics: Gingival Hyperplasia; Gingivitis; Humans; Hydantoins; Phenytoin | 1951 |
Effect of sodium kemithal, trimethadione, and sodium diphenylhydantoinate on skeletal muscle.
Topics: Barbital; Hydantoins; Ions; Muscle, Skeletal; Muscles; Phenytoin; Sodium; Sodium, Dietary; Trimethadione | 1951 |
Suicidal dilantin (sodium diphenylhydantoin) poisoning; a case report.
Topics: Aged; Humans; Hydantoins; Phenytoin; Sodium; Suicidal Ideation | 1951 |
The mode of action of sodium diphenylhydantoinate (dilantin) in epilepsy.
Topics: Epilepsy; Hydantoins; Phenytoin | 1951 |
Drug-modified electric shock therapy; clinical response to partial seizures facilitated by the anticonvulsant drugs, diphenylhydantoin and mephenesin, alone and in combination.
Topics: Anticonvulsants; Convulsive Therapy; Electroconvulsive Therapy; Humans; Hydantoins; Mephenesin; Phenytoin; Seizures | 1951 |
Effect of diphenyl hydantoin (Dilantin) on ether and pentobarbital (Nembutal) narcosis.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Biphenyl Compounds; Ether; Humans; Hydantoins; Pentobarbital; Phenytoin; Stupor | 1951 |
A comparative study of the anticonvulsant effect of the N-substituted 5,5-diallylbarbiturates and 5,5-diphenylhydantoins.
Topics: Anticonvulsants; Barbiturates; Humans; Hydantoins; Phenytoin; Pilocarpine; Seizures | 1951 |
[Acute phenobarbital and diphenylhydantoin poisoning].
Topics: Barbiturates; Cardiovascular Agents; Humans; Hydantoins; Phenobarbital; Phenytoin | 1952 |
Active-site characteristics of CYP2C19 and CYP2C9 probed with hydantoin and barbiturate inhibitors.
Topics: Aryl Hydrocarbon Hydroxylases; Barbiturates; Binding Sites; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Design; Enzyme Activation; Hydantoins; Mephenytoin; Mixed Function Oxygenases; Models, Chemical; Models, Molecular; Phenobarbital; Phenytoin; Protein Binding | 2004 |
Gingival hyperplasia resulting from diphenylhydantoin sodium; a review of the literature.
Topics: Gingiva; Gingival Hyperplasia; Hydantoins; Phenytoin; Sodium | 1950 |
Fatal granulocytopenia following hydantoins, mesantoin and dilantin; report of a case.
Topics: Agranulocytosis; Hydantoins; Mephenytoin; Phenytoin | 1950 |
A fixed skin eruption due to phenytoin sodium.
Topics: Exanthema; Humans; Hydantoins; Pharmaceutical Preparations; Phenytoin | 1950 |
Prevention of migraine attacks by dilantin sodium.
Topics: Animals; Behavior, Animal; Biomedical Research; Humans; Hydantoins; Migraine Disorders; Phenytoin; Social Behavior; Sodium | 1950 |
Accidental acute dilantin poisoning; report of a case with complete recovery in a nonepileptic child.
Topics: Cardiovascular Agents; Hydantoins; Phenytoin; Seizures | 1950 |
Dilantin sensitivity; report of a case of hepatitis with jaundice, pyrexia and exfoliative dermatitis.
Topics: Dermatitis, Exfoliative; Fever; Hepatitis; Humans; Hydantoins; Jaundice; Phenytoin; Viral Vaccines | 1950 |
Erythema bullosum malignans following dilantin therapy.
Topics: Erythema; Hydantoins; Phenytoin; Skin Diseases, Vesiculobullous | 1950 |
Toxic hepatic necrosis associated with taking dilantin, tridione and phenobarbital; report of a case.
Topics: Aged; Barbital; Hepatitis; Humans; Hydantoins; Liver; Liver Diseases; Phenobarbital; Phenytoin; Trimethadione | 1950 |
The use of 3,-methyl,5,phenylhydantoin (AC 114) in the treatment of epilepsy (a preliminary report).
Topics: Epilepsy; Hydantoins; Phenytoin | 1950 |
[Combined diphenylhydantoin and prominal therapy of cerebral spasms].
Topics: Anticonvulsants; Barbital; Hydantoins; Mephobarbital; Phenytoin; Spasm | 1950 |
Severe leukopenia due to diphenylhydantoin sodium; case report.
Topics: Hematopoietic System; Hydantoins; Leukocyte Disorders; Leukocytes; Leukopenia; Phenytoin; Sodium | 1950 |
[Diphenylhydantoin and vitamin C metabolism].
Topics: Ascorbic Acid; Carbohydrate Metabolism; Humans; Hydantoins; Metabolism; Phenytoin; Vitamins | 1950 |
A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cell Line, Transformed; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Evaluation; Electric Stimulation; Humans; Hydantoins; Ion Channel Gating; Male; Membrane Potentials; Mice; Models, Molecular; Patch-Clamp Techniques; Phenytoin; Seizures; Sodium Channels; Transfection | 2007 |
Pharmacokinetics of phenytoin and its metabolite, 4'-HPPH, after intravenous and oral administration of phenytoin to diabetic rats induced by alloxan or streptozotocin.
Topics: Administration, Oral; Alloxan; Animals; Anticonvulsants; Area Under Curve; Blood Proteins; Diabetes Mellitus, Experimental; Half-Life; Hydantoins; Injections, Intravenous; Liver; Phenytoin; Protein Binding; Rats; Rats, Sprague-Dawley; Streptozocin | 2008 |
Dilantin intoxication.
Topics: Cardiovascular Agents; Humans; Hydantoins; Phenytoin | 1949 |
The combined action of phenobarbitone and epanutin.
Topics: Anticonvulsants; Barbital; Barbiturates; Humans; Hydantoins; Phenobarbital; Phenytoin | 1947 |
Studies on the anticonvulsant properties of diphenylhydantoin.
Topics: Anticonvulsants; Hydantoins; Phenytoin; Seizures | 1946 |
Effects of continued administration of phenobarbital and diphenylhydantoin.
Topics: Barbital; Humans; Hydantoins; Phenobarbital; Phenytoin | 1946 |
Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin.
Topics: Animals; Hydantoins; Models, Molecular; Phenytoin; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Structure-Activity Relationship | 2011 |
Mechanochemical preparation of hydantoins from amino esters: application to the synthesis of the antiepileptic drug phenytoin.
Topics: Anticonvulsants; Cyclization; Esters; Hydantoins; Molecular Structure; Phenytoin; Solvents | 2014 |
A new method for simultaneous quantification of fosphenytoin, phenytoin and its primary metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin in whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Acetonitriles; Animals; Biomarkers; Chromatography, High Pressure Liquid; Hydantoins; Liquid-Liquid Extraction; Male; Methanol; Phenytoin; Rats; Rats, Wistar; Tandem Mass Spectrometry | 2018 |
Direct N
Topics: Anticonvulsants; Azides; Butanols; Hydantoins; Methylation; Phenytoin; Potassium | 2021 |