phenytoin has been researched along with glycine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (52.63) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geurts, M; Lambert, DM; Poupaert, JH; Scriba, GK | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Costa, E; Guidotti, A; Mao, CC; Suria, A | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Hansen, S; Kennedy, J; Perry, TL; Thompson, GB; Wada, JA | 1 |
| Anlezark, G; Balzamo, E; Horton, RW; Meldrum, BS; Trimble, M | 1 |
| Peterson, SL | 1 |
| Iversen, LL; Minchin, MC | 1 |
| De Hesse, C; Houck, JC; Jacob, R | 1 |
| Donelli, MG; Garattini, S; Rosso, R | 1 |
| Bruun, A; Ehinger, B | 1 |
| Arimura, GK; Blasquez, J; Halloran, M; Lutcher, CL; Yunis, AA | 1 |
| Lajtha, A; Toth, E | 1 |
| McLean, MJ; Wamil, AW | 1 |
| Kim, HS; Lee, DC | 1 |
| Lambert, DM; Scriba, GK | 1 |
| Kim, HS; Lee, DC; Oh, KH; Park, JH | 1 |
1 review(s) available for phenytoin and glycine
| Article | Year |
|---|---|
New concepts on the mechanism of action of benzodiazepines.
Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra | 1975 |
18 other study(ies) available for phenytoin and glycine
| Article | Year |
|---|---|
N-(benzyloxycarbonyl)glycine esters and amides as new anticonvulsants.
Topics: 3-Mercaptopropionic Acid; Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Esters; Glycine; Male; Mice; Mice, Inbred Strains; Neurotoxins; Pentylenetetrazole; Radioligand Assay; Rats; Rats, Wistar; Receptors, Glycine; Seizures; Spinal Cord; Strychnine | 1998 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Amino acids in human epileptogenic foci.
Topics: Adolescent; Adult; Amino Acids; Animals; Aspartic Acid; Cerebral Cortex; Child; Cystathionine; Epilepsies, Partial; gamma-Aminobutyric Acid; Glutamates; Glycine; Humans; Phenytoin; Rats; Taurine | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile | 1975 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Release of (3H)gamma-aminobutyric acid from glial cells in rat dorsal root ganglia.
Topics: Acetates; Alanine; Aminobutyrates; Animals; Calcium; Carbon Radioisotopes; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glycine; Hydroxylamines; Kinetics; L-Lactate Dehydrogenase; Lanthanum; Leucine; Magnesium; Neuroglia; Osmolar Concentration; Phenytoin; Potassium; Rats; Time Factors; Tritium | 1974 |
The effect of ageing upon collagen metabolism.
Topics: Aging; Animals; Body Weight; Burns; Citrates; Collagen; Cycloheximide; Desoxycorticosterone; Glycine; Hydrocortisone; Hydroxyproline; Liver Glycogen; Male; Microbial Collagenase; Peptide Hydrolases; Phenytoin; Prednisolone; Proline; Puromycin; Rats; Skin; Sodium Chloride; Tissue Extracts | 1967 |
On the neurotoxic effects induced by alkylating agents.
Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan | 1966 |
Uptake of the putative neurotransmitter, glycine, into the rabbit retina.
Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Desipramine; Diazepam; Dinitrophenols; Glutamates; Glutethimide; Glycine; Haloperidol; Lysine; Meprobamate; Neurons; Neurotransmitter Agents; Ouabain; Phenytoin; Rabbits; Retina; Synaptic Transmission; Temperature | 1972 |
Biochemical lesion in Dilantin-induced erythroid aplasia.
Topics: Adolescent; Autoradiography; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Carbon Isotopes; DNA; Erythrocytes; Fluorescent Antibody Technique; Folic Acid; Formates; Glycine; Humans; In Vitro Techniques; Injections, Intravenous; Iron Isotopes; Male; Nucleosides; Phenytoin; Riboflavin; RNA; Tritium; Vitamin B 12 | 1967 |
Glycine potentiates the action of some anticonvulsant drugs in some seizure models.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Glycine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1984 |
Phenytoin blocks N-methyl-D-aspartate responses of mouse central neurons.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Glycine; In Vitro Techniques; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Potassium; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Tetrodotoxin | 1993 |
Optimization of a heterogeneous reaction system for the production of optically active D-amino acids using thermostable D-hydantoinase.
Topics: Amidohydrolases; Chromatography, High Pressure Liquid; Enzyme Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Phenytoin; Spectrophotometry, Infrared; Temperature | 1998 |
Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin.
Topics: Animals; Anticonvulsants; Glycine; Phenytoin; Prodrugs; Rats | 1999 |
Modeling and kinetic analysis of the reaction system using whole cells with separately and co-expressed D-hydantoinase and N-carbamoylase.
Topics: Agrobacterium tumefaciens; Amidohydrolases; Catalysis; Computer Simulation; Geobacillus stearothermophilus; Glycine; Hydrogen-Ion Concentration; Models, Biological; Models, Chemical; Phenytoin; Sensitivity and Specificity; Stereoisomerism | 2002 |