phenytoin and glutethimide

phenytoin has been researched along with glutethimide in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199030 (78.95)18.7374
1990's1 (2.63)18.2507
2000's2 (5.26)29.6817
2010's4 (10.53)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Einhorn, R; Franki, N; Hays, RM; Levine, SD1
Lawrence, RC; Lovering, EG; Watson, JR1
Mohrbacher, RJ; Riendeau, CJ; Werner, M1
Buhl, SN; Kowalski, P; Vanderlinde, RE1
Trebbin, WM1
Bell, GD; Cartwright, S; Chaplain, S; Henry, DA; Kitchingman, G; Langman, MJ; Sharpe, G1
Berk, PD; Blaschke, TF; Martin, JF; Plotz, PH; Scharschmidt, BF1
Lucas, RE; Montgomery, WS1
Kyogoku, Y; Yu, NT1
Gogerty, JH; Iorio, LC; Ryan, EA1
Cadden, JJ; Feigelson, EB1
Mandel, HG; Riis, M1
Bruun, A; Ehinger, B1
McBay, AJ1
Olson, MV; Smith, RP1
Cooper, RG; Greaves, MS; Owen, G1
Berk, PD; Blaschke, TF; Guyther, JR; Scharschmidt, BF; Vergalla, JM; Waggoner, JG1
Levy, SK; Schwartz, T1
Darcey, B; Evenson, MA; Jones, P1
Elliott, HW; Hine, CH; Nomof, N; Parker, KD; Wright, JA1
Mulé, SJ1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ1
Hynes, HE; Recker, RR1
Everitt, BJ; Hall, GH; Taylor, EM1
de Zeeuw, RA; Feitsma, MT1
Aeberli, P; Gogerty, J; Houlihan, WJ1
Perry, W; Stamp, TC1
Greim, H1
CHIESARA, E; KATO, R; VASSANELLI, P1
BURNS, JJ1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1
Szpot, P; Tusiewicz, K; Wachełko, O; Zawadzki, M1

Reviews

4 review(s) available for phenytoin and glutethimide

ArticleYear
Toxicological findings in fatal poisonings.
    Clinical chemistry, 1973, Volume: 19, Issue:4

    Topics: 1-Propanol; Alcoholic Intoxication; Amphetamine; Carbon Monoxide Poisoning; Chloral Hydrate; Chlordiazepoxide; Dextropropoxyphene; Diazepam; Ethchlorvynol; Glutethimide; Heroin; Humans; Meprobamate; Methadone; Methanol; Morphine; Orphenadrine; Paraldehyde; Pentazocine; Phenothiazines; Phenytoin; Poisoning; Quinine; Salicylates; Toxicology; Tranquilizing Agents

1973
Drug-induced methemoglobinemia.
    Seminars in hematology, 1973, Volume: 10, Issue:3

    Topics: Analgesics; Anesthetics, Local; Animals; Anti-Infective Agents; Anticoagulants; Cats; Dogs; Exchange Transfusion, Whole Blood; Glutethimide; Guinea Pigs; Hemoglobinopathies; Hemoglobins; Humans; Hydroxylamines; Hyperbaric Oxygenation; Methemoglobinemia; Methylene Blue; Mice; Oxidation-Reduction; Phenytoin; Vasodilator Agents

1973
[Enzyme induction in the liver changes drug activity].
    Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20

    Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors

1980
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Other Studies

34 other study(ies) available for phenytoin and glutethimide

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Vasopressin-stimulated movement of drugs and uric acid across the toad urinary bladder.
    Kidney international, 1976, Volume: 9, Issue:1

    Topics: Adenine; Animals; Anti-Bacterial Agents; Anura; Butanols; Cell Membrane Permeability; Cyclic AMP; Cyclohexanones; Female; Fluorouracil; Glutethimide; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Phloretin; Stimulation, Chemical; Uric Acid; Urinary Bladder; Vasopressins

1976
Simple GLC analysis of anticonvulsant drugs in commercial dosage forms.
    Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:7

    Topics: Anticonvulsants; Chromatography, Gas; Glutethimide; Hydantoins; Mephenytoin; Phenytoin; Primidone; Succinimides

1978
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
    Clinical chemistry, 1979, Volume: 25, Issue:12

    Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital

1979
Quantitative toxicology: interlaboratory and intermethod evaluation in New York State.
    Clinical chemistry, 1978, Volume: 24, Issue:3

    Topics: Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Humans; Immunoenzyme Techniques; New York; Phenytoin; Procainamide; Quality Control; Spectrophotometry, Ultraviolet; Theophylline

1978
Hemodialysis and pregnancy.
    JAMA, 1979, Apr-27, Volume: 241, Issue:17

    Topics: Acute Kidney Injury; Adolescent; Adult; Chloral Hydrate; Female; Glutethimide; Humans; Infant, Newborn; Kidney Failure, Chronic; Peritoneal Dialysis; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Renal Dialysis

1979
The [14C]-aminopyrine breath test. A comparison of different forms of analysis.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:6

    Topics: Aminopyrine; Breath Tests; Carbon Dioxide; Epilepsy; Glucaric Acid; Glutethimide; Humans; Liver Diseases; Phenytoin; Time Factors

1979
Unconjugated hyperbilirubinemia. Physiologic evaluation and experimental approaches to therapy.
    Annals of internal medicine, 1975, Volume: 82, Issue:4

    Topics: Adult; Albumins; Animals; Bilirubin; Crigler-Najjar Syndrome; Ethosuximide; Female; Gilbert Disease; Glutethimide; Hemolysis; Humans; Hyperbilirubinemia; Liver; Phenobarbital; Phenytoin; Phototherapy; Plasmapheresis; Rats; Seizures

1975
Glutethimide withdrawal syndrome--the ethics of supply and demand.
    Australian and New Zealand journal of medicine, 1992, Volume: 22, Issue:6

    Topics: Aged; Glutethimide; Humans; Male; Phenytoin; Seizures; Substance Withdrawal Syndrome

1992
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
    Biochimica et biophysica acta, 1973, Nov-26, Volume: 331, Issue:1

    Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide

1973
Anticonvulsant testing with a new analeptic convulsant: N-sulfamoyl-hexahydro-azepine (Sah 41-178).
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 206, Issue:2

    Topics: Acetamides; Animals; Anticonvulsants; Azepines; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Glutethimide; Haloperidol; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Strychnine; Sulfonamides; Trimethadione

1973
Changing patterns of drug abuse in New York City.
    The American journal of drug and alcohol abuse, 1974, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Amphetamines; Antipsychotic Agents; Barbiturates; Codeine; Dextropropoxyphene; Female; Glutethimide; Heroin Dependence; Humans; Male; Methadone; Morphine; New York City; Phenothiazines; Phenytoin; Quinine; Substance-Related Disorders

1974
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea

1970
Uptake of the putative neurotransmitter, glycine, into the rabbit retina.
    Investigative ophthalmology, 1972, Volume: 11, Issue:4

    Topics: Alanine; Aminobutyrates; Animals; Aspartic Acid; Desipramine; Diazepam; Dinitrophenols; Glutamates; Glutethimide; Glycine; Haloperidol; Lysine; Meprobamate; Neurons; Neurotransmitter Agents; Ouabain; Phenytoin; Rabbits; Retina; Synaptic Transmission; Temperature

1972
Gas-liquid chromatographic isolation, identification, and quantitation of some barbiturates, glutethimide, and diphenylhydantoin in whole blood.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Barbiturates; Chromatography, Gas; Glutethimide; Humans; Methods; Phenytoin; Spectrophotometry

1972
Crigler-Najjar syndrome: an unusual course with development of neurologic damage at age eighteen.
    Pediatric research, 1974, Volume: 8, Issue:5

    Topics: Adolescent; Alkaline Phosphatase; Bilirubin; Brain Damage, Chronic; Brain Diseases; Carbon Monoxide; Erythrocyte Aging; Female; Glucuronates; Glutethimide; Humans; Hyperbilirubinemia, Hereditary; Indocyanine Green; Kanamycin; Liver Function Tests; Phenobarbital; Phenytoin; Phototherapy; Plasmapheresis; Protein Binding; Radioisotopes; Renal Dialysis; Salicylamides; Sulfobromophthalein; Syndrome; Transaminases

1974
New mixed bed column for rapid gas-liquid chromatographic determination of sedatives and Dilantin in serum.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Jul-15, Volume: 54, Issue:1

    Topics: Amobarbital; Barbiturates; Chromatography, Gas; Evaluation Studies as Topic; Glutethimide; Humans; Methods; Pentobarbital; Phenobarbital; Phenytoin; Secobarbital; Time Factors

1974
Simultaneous measurement of diphenylhydantoin and primidone in serum by gas-liquid chromatography.
    Clinical chemistry, 1970, Volume: 16, Issue:2

    Topics: Barbiturates; Blood Chemical Analysis; Chromatography, Gas; Glutethimide; Humans; Methods; Phenytoin; Primidone; Time Factors

1970
Blood and urine concentrations of subjects receiving barbiturates, meprobamate, glutethimide, or diphenylhydantoin.
    Clinical toxicology, 1970, Volume: 3, Issue:1

    Topics: Adult; Barbiturates; Depression, Chemical; Glutethimide; Humans; Male; Meprobamate; Motor Activity; Neurologic Manifestations; Phenytoin; Time Factors

1970
Routine identification of drugs of abuse in human urine. I. Application of fluorometry, thin-layer and gas-liquid chromatography.
    Journal of chromatography, 1971, Mar-03, Volume: 55, Issue:2

    Topics: Amphetamine; Analgesics; Barbiturates; Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Glutethimide; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Indicators and Reagents; Morphinans; Morphine; Phenothiazines; Phenytoin; Psychopharmacology; Quinine; Substance-Related Disorders; Tranquilizing Agents

1971
Dialysis of drugs against activated charcoal.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3

    Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors

1971
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Adolescent; Adult; Aminosalicylic Acids; Anemia, Aplastic; Aspirin; Barbiturates; Child; Child, Preschool; Chloramphenicol; Chlorpropamide; Colchicine; Female; Glutethimide; Heparin; Humans; Infant; Isoniazid; Male; Middle Aged; Phenytoin; Riboflavin

1969
The sedative and anticonvulsant activity of some substituted pyrrolidones and piperidones.
    British journal of pharmacology and chemotherapy, 1965, Volume: 25, Issue:3

    Topics: Animals; Behavior, Animal; Cats; Chlorpromazine; Dogs; Female; Glutethimide; Guinea Pigs; Male; Meprobamate; Mice; Phenobarbital; Phenytoin; Piperidines; Pyrrolidinones; Rabbits; Rats

1965
Separation and identification of some barbiturates, bromoureides, phenytoin and glutethimide by means of two-dimensional thin-layer chromatography.
    Pharmaceutisch weekblad, 1966, Oct-28, Volume: 101, Issue:43

    Topics: Barbiturates; Chromatography, Thin Layer; Glutethimide; Hypnotics and Sedatives; Phenytoin

1966
Neuropharmacological investigation of N-benzylsulfamides.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:4

    Topics: Amides; Animals; Anticonvulsants; Behavior, Animal; Cats; Central Nervous System; Chemistry, Organic; Drug Antagonism; Electric Stimulation; Electrophysiology; Electroshock; Glutethimide; Hypnotics and Sedatives; Imides; Locomotion; Mice; Organic Chemistry Phenomena; Phenytoin; Seizures; Strychnine

1967
Urinary D-glucaric acid excretion during rifampicin/isoniazid and anticonvulsant enzyme induction.
    Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Enzyme Induction; Female; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Glutethimide; Humans; Isoniazid; Liver; Male; Middle Aged; Phenytoin; Rifampin; Sugar Acids

1984
Increased activity of microsomal strychnine-metabolizing enzyme induced by phenobarbital and other drugs.
    Biochemical pharmacology, 1962, Volume: 11

    Topics: Glutethimide; Meprobamate; Nikethamide; Phenobarbital; Phenytoin; Primidone; Strychnine; Thiopental; Urethane

1962
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine

1965
New approach for barbiturates, phenytoin, methyprylon and glutethimide determination and fragmentation (UHPLC-MS/MS).
    Journal of pharmaceutical and biomedical analysis, 2023, May-10, Volume: 228

    Topics: Barbiturates; Chromatography, High Pressure Liquid; Glutethimide; Phenytoin; Tandem Mass Spectrometry

2023