phenytoin has been researched along with flunarizine in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 8 (50.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Akaike, N; Kameda, H; Kataoka, M; Takahashi, K; Ueno, S | 1 |
| De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
| Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
| Marrannes, R; Reid, KH; Wauquier, A | 1 |
| Abe, K; Kogure, K | 1 |
| Bebin, M; Bleck, TP | 1 |
| Drake, ME; Mikati, M; Olson, L; Pellock, JM; Pledger, GW; Sackellares, JC; Sahlroot, JT; Treiman, DM; Tsay, JY; Wright, FS | 1 |
| Pleuvry, BJ; Rodger, C | 1 |
| Ishide, N | 1 |
| Mahmood, I; Sahlroot, JT | 1 |
| David, J; Joseph, S; Joseph, T | 1 |
3 review(s) available for phenytoin and flunarizine
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
New anticonvulsant drugs. Focus on flunarizine, fosphenytoin, midazolam and stiripentol.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Child, Preschool; Cross-Over Studies; Dioxolanes; Double-Blind Method; Epilepsy; Flunarizine; Humans; Midazolam; Middle Aged; Phenytoin; Pilot Projects; Prodrugs | 1994 |
Intracellular calcium modulators for cardiac muscle in pathological conditions.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Benzothiazoles; Caffeine; Calcium; Calcium Channel Blockers; Dantrolene; Flunarizine; Homeostasis; Humans; Magnesium; Models, Cardiovascular; Muscle Relaxants, Central; Myocardial Contraction; Myocardium; Phenytoin; Piperidines; Ryanodine; Sarcoplasmic Reticulum; Thiazepines; Thiazoles | 1996 |
3 trial(s) available for phenytoin and flunarizine
| Article | Year |
|---|---|
New anticonvulsant drugs. Focus on flunarizine, fosphenytoin, midazolam and stiripentol.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Child, Preschool; Cross-Over Studies; Dioxolanes; Double-Blind Method; Epilepsy; Flunarizine; Humans; Midazolam; Middle Aged; Phenytoin; Pilot Projects; Prodrugs | 1994 |
Flunarizine for treatment of partial seizures: results of a concentration-controlled trial.
Topics: Adolescent; Adult; Aged; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Flunarizine; Half-Life; Humans; Male; Middle Aged; Phenytoin; Treatment Outcome | 1994 |
A limited sampling method for the estimation of flunarizine area under the curve (AUC) and maximum plasma concentration (Cmax).
Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Drug Therapy, Combination; Flunarizine; Humans; Linear Models; Models, Biological; Models, Statistical; Phenytoin | 1997 |
11 other study(ies) available for phenytoin and flunarizine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Effects of phenytoin and flunarizine on the rise in extracellular potassium induced by repetitive stimulation of rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Cortical Spreading Depression; Electric Stimulation; Extracellular Space; Flunarizine; Male; Phenytoin; Potassium; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Prevention of an increase in susceptibility to calcium in a neuroblastoma cell line.
Topics: Calcium; Cell Membrane Permeability; Cell Survival; Chlorpromazine; Cold Temperature; Flunarizine; Humans; Neuroblastoma; Pentobarbital; Phenytoin; Tumor Cells, Cultured | 1987 |
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures | 1993 |
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid | 1998 |