phenytoin has been researched along with ethosuximide in 354 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 245 (69.21) | 18.7374 |
| 1990's | 34 (9.60) | 18.2507 |
| 2000's | 29 (8.19) | 29.6817 |
| 2010's | 44 (12.43) | 24.3611 |
| 2020's | 2 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Johnson, DN; Kilpatrick, BF; Kinnier, WB; Lo, YS; Moses, LM; Sutherland, DB; Taylor, CR; Tomczuk, BE | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Iqbal, MT; Kwon, CH; Wurpel, JN | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Kadaba, PK | 1 |
| Conley, JD; Kohn, H | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Flaherty, PT; Greenwood, TD; Manheim, AL; Wolfe, JF | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Bharathwajan, N; Patel, SK; Ragavendran, JV; Reddy, IV; Sriram, D; Stables, J; Yogeeswari, P | 1 |
| Alam, M; Arshad, MF; Bhat, MA; Khan, SA; Pandeya, SN; Rana, A; Siddiqui, N; Stables, J | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Jatav, V; Kashaw, S; Mishra, P; Stables, JP | 2 |
| Kavya, R; Nageswari, Y; Ragavendran, JV; Sreevatsan, N; Sriram, D; Stables, J; Vanitha, K; Yogeeswari, P | 1 |
| Ragavendran, JV; Ranganadh, V; Sahitya, P; Sriram, D; Yogeeswari, P | 1 |
| Kamiński, K; Obniska, J | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Kotapati, S; Ragavendran, JV; Sriram, D; Stables, J; Yogeeswari, P | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Ahsan, W; Siddiqui, N | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ahsan, W; Alam, O; Gilani, SJ; Khan, SA; Mullick, P; Siddiqui, N; Verma, SP | 1 |
| Alkskas, IA; Azam, F; El-Gnidi, BA | 1 |
| He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Deshmukh, R; Kharya, MD; Mishra, P; Rajak, H; Sharma, AK; Veerasamy, R | 1 |
| Byrtus, H; Kamiński, K; Karolak-Wojciechowska, J; Obniska, J; Pawłowski, M; Szczesio, M | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Atamanyuk, D; Kamiński, K; Obniska, J; Wiklik, B | 1 |
| Chodkowski, A; Dawidowski, M; Herold, F; Kleps, J; Szulczyk, P; Wilczek, M | 1 |
| Kamiński, K; Obniska, J; Rzepka, S | 2 |
| Byrtus, H; Czopek, A; Kamiński, K; Obniska, J; Pawłowski, M | 1 |
| Prakash, CR; Raja, S | 1 |
| Guo, H; He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Alagarsamy, V; Prakash, CR; Saravanan, G | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Kharya, MD; Raghuvanshi, K; Rajak, H; Sah, AK; Sharma, PC; Singh Pawar, R; Singh Thakur, B; Singh, A; Veerasamy, R | 1 |
| Chlebek, I; Kamiński, K; Liana, P; Obniska, J; Pękala, E | 1 |
| Bahare, RS; Khan, SA; Malik, S | 1 |
| Chlebek, I; Kamiński, K; Obniska, J; Rzepka, S; Wiklik, B | 1 |
| Dawidowski, M; Kubica, K; Skolmowski, M; Turło, J; Wilczek, M | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Ahuja, P; Siddiqui, N | 1 |
| Ahuja, P; Khan, SA; Malik, S; Sahu, K | 1 |
| Chońska, J; Dawidowski, M; Mika, W; Turło, J | 1 |
| Hong, X; Hu, X; Li, J; Liu, P; Lou, J; Wang, T; Wang, Z; Xiao, Y | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Filipek, B; Kamiński, K; Obniska, J; Pękala, E; Powroźnik, B; Rapacz, A; Rybka, S; Żmudzki, P | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Góra, M; Kamiński, K; Obniska, J; Rapacz, A; Rybka, S; Sałat, K; Żmudzki, P | 1 |
| Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM | 1 |
| Jamal Gilani, S; Kala, C; Prakash Dixit, S; Sarim Imam, S; Zaheen Hassan, M | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Bohlen, N; Hertl, M | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Lascelles, PT; Patsalos, PN | 4 |
| Dreifuss, FE | 1 |
| Flachs, H; Gram, L; Parnas, J | 2 |
| Kutt, H | 3 |
| Schmidt, D | 3 |
| Snead, OC | 1 |
| Penin, H | 1 |
| Deisenhammer, E; Sommer, R | 2 |
| Aucamp, AK | 1 |
| Gandhi, IC; Jindal, MN; Patel, VK | 1 |
| Ferrendelli, JA; Kinscherf, DA | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Stores, G | 1 |
| Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 1 |
| Conomy, JP | 1 |
| Göbel, W; Löscher, W | 1 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Newmark, ME; Penry, JK | 1 |
| Reith, H; Schäfer, H | 1 |
| Livingston, S; Pauli, LL; Pruce, I | 1 |
| Trimble, M | 1 |
| Crawford, RD; Davis, HL; Johnson, DD | 1 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fierz, L; Karbowski, K; Robert, F | 1 |
| Brickley, JJ; Englander, RN; Hanna, GR; Johnson, RN | 1 |
| Swanson, PD | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Fröscher, W | 1 |
| Rylance, GW | 1 |
| Abraham, CV; Gresham, D | 1 |
| Varma, R | 1 |
| Brotchi, J; Dresse, A; Gerebtzoff, MA; Lepot, M; Scuvee-Moreau, J | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H; Seidel, D | 1 |
| Kutt, H; Louis, S; Newman, SM; Turner, IM | 1 |
| Plenge, KL | 1 |
| Köhler, E; Leuschner, U; Meyer, FP; Quednow, B; Walther, H | 1 |
| Brown, HW; Clark, BG; Dawson, GW | 1 |
| Müller-Oerlinghausen, B; Riedel, E | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Freeman, JM; Singer, HS | 1 |
| Gibberd, FB | 2 |
| Richens, A | 1 |
| Chan, HL; Teoh, PC | 1 |
| Bolin, RH; Bruya, MA | 1 |
| Consroe, P; Eisenstein, D; Martin, P | 1 |
| Hill, RE; Latham, AN | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H | 1 |
| Bius, DL; Boyles, LW; Dudley, KH; Kraus, BL | 1 |
| McElhatton, PR; Sullivan, FM | 1 |
| Brachet-Liermain, A; Centraud, B; Loiseau, P | 1 |
| Anderson, RC | 1 |
| Adams, RF; Vandemark, FL | 1 |
| Ferrendelli, JA; Sohn, RS | 1 |
| Latham, AN; Varlow, G | 1 |
| Cook, WL; Gerald, MC; Gupta, TK; Witiak, DT | 1 |
| Reynolds, EH; Trimble, MR | 2 |
| Rane, A; Wilson, JT | 1 |
| Fishman, L; Hanson, V; Singsen, BH | 1 |
| Danielson, MG; Fowler, GW; Julien, RM | 1 |
| Fine, RN; Malekzadeh, MH; Pennisi, AJ; Wassner, SJ | 1 |
| Johnson, J | 1 |
| Berk, PD; Blaschke, TF; Martin, JF; Plotz, PH; Scharschmidt, BF | 1 |
| Baars, I; Guelen, PJ; Kleijn, E; Vree, TB | 1 |
| Bishun, NP; Smith, NS; Williams, DC | 1 |
| Blaskovics, ME; Podosin, RL; Roe, TF | 1 |
| Gloor, P; Guberman, A; Sherwin, AL | 1 |
| Dam, M; Kiørboe, E | 1 |
| Buddington, R; Daly, DD; Penry, JK; Pippenger, CE; White, BG | 1 |
| Hill, JG; Soldin, SJ | 1 |
| Watanabe, M; Yagi, K | 1 |
| Edwards, JA; Skeen, GA; White, HS | 1 |
| Dean, PM; Edwardson, JM | 1 |
| Declerck, AC; Wauquier, A | 1 |
| Wyllie, E; Wyllie, R | 1 |
| Bartels, H; Hebestreit, H; Mingers, AM; Pannenbecker, J | 1 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L | 1 |
| Cosgrove, M; Pople, S; Wallace, SJ | 1 |
| Blennow, G; Heijbel, J; Sandstedt, P; Tonnby, B | 1 |
| Clark, R; Poling, A; Schlinger, H | 1 |
| Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
| Logan, RW; Paton, RD | 1 |
| Clark, R; Picker, M; Poling, A; Vande Polder, D | 1 |
| Macdonald, RL; McLean, MJ | 1 |
| Blakely, E; Picker, M; Poling, A; White, W | 1 |
| Lee, EK; Walters, JR; Waszczak, BL | 1 |
| Shinnar, S | 1 |
| Krall, RL; Resor, SJ | 1 |
| Bourgeois, BF | 1 |
| García Sagredo, JM | 1 |
| Depaulis, A; Kiesmann, M; Marescaux, C; Micheletti, G; Vergnes, M; Warter, JM | 2 |
| Bachmann, KA; Jauregui, L; Martin, M; Schwartz, J; Sullivan, TJ | 1 |
| Lackner, TE | 1 |
| Kaneda, H; Kaneto, H; Kawatani, S | 1 |
| Amit, R; Rottem, M; Yatziv, S | 1 |
| Piredda, SG; Swinyard, EA; Woodhead, JH | 1 |
| Fromm, GH | 1 |
| Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| Dailey, JW; Jobe, PC | 1 |
| Picker, M; Poling, A; White, W | 1 |
| Frey, HH; Löscher, W | 1 |
| Freeman, JM; Vining, EP | 1 |
| Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Biarese, V; Cargnino, M; Lerda, R; Lovisetto, P; Mairano, D; Marchi, L | 1 |
| Krip, G; Vazquez, AJ | 1 |
| Davidson, S; Falconer, MA | 1 |
| Kutt, H; Penry, JK | 1 |
| Bochentin, W; Koeppe, P; Kraft, D; Opitz, A; Schaefer, K; von Herrath, D | 1 |
| Eadie, MJ; Tyrer, JH | 1 |
| Forrest, TP; Gilroy, ML; Vohra, MM; Yung, DK | 1 |
| Bochner, F; Eadie, MJ; Hooper, WD; Sutherland, JM; Tyrer, JH | 1 |
| Kyogoku, Y; Yu, NT | 1 |
| Deitrich, RA; Erwin, VG | 1 |
| Parsonage, M | 1 |
| Hansen, JM; Hansen, OE; Kristensen, M; Lund, V | 1 |
| Cohn, R | 1 |
| Place, JF; Rud, C; Vedsö, S | 1 |
| Meyer, JG | 2 |
| Peterson, DI; Zweig, RW | 1 |
| Forman, PM | 1 |
| Böhl, I; Engel, E; Schulz, H | 1 |
| Millichap, JG | 2 |
| Fromm, GH; Kohli, CM | 1 |
| Eisen, AA; Sherwin, AL; Woods, JF | 1 |
| Hooshmand, H; Suter, CG | 1 |
| Freeman, JM; Lietman, PS | 1 |
| Banziger, R; Hane, D | 1 |
| Wilson, J | 1 |
| Gentilucci, C; Proto, A | 1 |
| Rowan, AJ; Scott, D | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Toothill, C | 1 |
| Leibovitz, U | 1 |
| Kutt, H; Louis, S | 1 |
| Beam, RE | 1 |
| Dow, RC; Forfar, JC; McQueen, JK | 1 |
| Garrettson, LK | 1 |
| Gregoriades, AD | 1 |
| Green, JB; Solow, EB | 1 |
| Panther, W | 1 |
| Frey, HH; Meyer, H | 1 |
| Cremers, HM; Verheesen, PE | 1 |
| Hill, RM; Horning, MG; McCulley, LB; Morgan, NF; Verniaud, WM | 1 |
| Perchalski, RJ; Wilder, BJ | 1 |
| Wilson, JT | 1 |
| Kurata, D; Wilkinson, GR | 1 |
| Carter, S; Gold, A | 1 |
| Ando, J; Kiehi, Y | 1 |
| Green, JB | 1 |
| Haining, RG; Labbé, RF; Lefebvre, EB | 1 |
| Borgstedt, AD; Bryson, MF; Forbes, GB; Young, LW | 1 |
| Harms, D | 1 |
| Kästner, I; Kermes, U; Rougerie, A | 1 |
| Hommes, OR; Houben, PF; Knaven, PJ | 1 |
| Andermann, F | 1 |
| DeVivo, DC; Palkes, H; Prensky, AL | 1 |
| Fletcher, BD; Lussier-Lazaroff, J | 1 |
| Gilbert, JC; Gray, P; Heaton, GM | 1 |
| Ferngren, H; Paalzow, L | 1 |
| Breuer, U; Lempp, R | 1 |
| Collins, AJ; Horlington, M | 1 |
| Frey, HH; Kampmann, E | 2 |
| Maheshwari, MC | 1 |
| Neuvonen, PJ; Tokola, RA | 1 |
| Mantegazza, P; Martini, A; Panerai, AE; Sacerdote, P | 1 |
| Karler, R; Turkanis, SA | 1 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Porter, SE; Smith, CH; Tieber, VL | 1 |
| Haven, GT; Kiser, EJ; Studts, D | 1 |
| Ou, CN; Rognerud, CL | 1 |
| Dichter, MA; Heller, AH; Sidman, RL | 1 |
| Rowan, AJ | 1 |
| Crema, A; Perucca, E | 1 |
| Bleck, TP | 1 |
| Asconapé, J; Penry, JK | 1 |
| Reynolds, EH | 1 |
| Callaghan, N; Keating, J; O'Dwyer, R | 1 |
| Albright, PS; Bruni, J | 1 |
| Frey, HH; Löscher, W; Reiche, R; Schultz, D | 1 |
| Ramsay, RE | 1 |
| Koryntová, H; Mares, P; Maresová, D; Pohl, M; Seidl, J; Velísek, L | 1 |
| Classen, W; Mondadori, C | 1 |
| Picker, M; Poling, A | 1 |
| Porter, RJ; Theodore, WH | 1 |
| De Paiva, VJ; Subirana, A; Subirana, M | 1 |
| Davies, SM | 1 |
| Gathman, G; Herrick, MK; Mallow, DW | 1 |
| Alric, R; Arce-Corrales, L; Blayac, JP; Puech, R | 1 |
| Friis, ML; Hvidberg, E | 1 |
| Chan, K; Lok, S; Teoh, R | 1 |
| Karkos, J | 1 |
| Aly, AE; El-Sayed, MG; Kadri, M; Moustafa, AM | 1 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Karlov, VA | 1 |
| Reynolds, EH; Shorvon, SD | 1 |
| Chattha, AS; Fromm, GH; Glass, JD; Martinez, AJ | 1 |
| Aminoff, MJ | 1 |
| Bustamante, L; Goldensohn, ES; Lueders, H; Pippenger, C | 1 |
| Scollo-Lavizzari, G | 1 |
| Clifford, DB; Dodson, WE; Ferrendelli, JA; Lothman, EW | 1 |
| Cohan, SL | 1 |
| Koch, KM; Levy, RH | 1 |
| Kabra, PM; Marton, LJ; Nelson, MA | 1 |
| Cooper, JD; Trevor, SC; Turnell, DC | 1 |
| Neels, HM; Scharpé, SL; Totté, JA; Verkerk, RM; Vlietinck, AJ | 1 |
| Fujimoto, S; Matsuda, I; Matsukura, M; Nishiyama, S | 1 |
| Browne, TR; Szabo, GK | 1 |
| Meijer, JW; Rambeck, B; Riedmann, M | 2 |
| Bannister, SJ; Dolan, JW; Snyder, LR; van der Wal, S | 1 |
| Dietzler, DN; Hoelting, CR; Leckie, MP; Smith, CH; Tieber, VL | 1 |
| Külpmann, WR; Oellerich, M | 1 |
| Berlit, P; Bonjour, JP; Krause, KH | 1 |
| Frieder, B; Karpiak, SE; Rapport, MM | 1 |
| Arranz Peña, MI | 1 |
| Maheshwari, MC; Padmini, R | 1 |
| Gross, AJ; Morton, WA; Saunders, S; Wannamaker, BB | 1 |
| Christofides, JA; Fry, DE | 1 |
| Soldin, SJ | 1 |
| Burnham, WM; King, GA; Livingston, KE | 1 |
| Hässler, A; Hermann, J; John, K; John, R | 1 |
| Sterman, MB | 1 |
| Cloyd, J; Garnett, WR; Holmes, GL; Meyer, MC; Schiffer, JR | 1 |
| Amano, T; Fujita, Y; Hanaya, R; Matsubayashi, H; Sasa, M; Serikawa, T; Ujihara, H; Uozumi, T | 1 |
| Korinthenberg, R; Wehrle, L; Zimmerhackl, LB | 1 |
| Hekster, YA; Keyser, A; Lammers, MW; Meinardi, H; Renier, WO; van Lier, H; Wijsman, DJ | 1 |
| Schmutz, A; Thormann, W | 1 |
| Baba, H; Ono, K; Sugai, S | 1 |
| Pleuvry, BJ; Rodger, C | 1 |
| Bachmann, KA; Jauregui, L | 1 |
| Hirohashi, M; Kitano, Y; Nomura, M; Takasuna, K; Usui, C | 1 |
| Cavallaro, G; Fresta, M; Giammona, G; Puglisi, G; Wehrli, E | 1 |
| Bartoli, A; Gatti, G; Giaccone, M; Latella, MA; Marchiselli, R; Perucca, E; Pisani, F | 1 |
| Cooper, RM; Krenz, NR | 1 |
| Perucca, E; Pisani, F; Spina, E | 1 |
| Diomedi, M; Gigli, GL; Masala, C; Placidi, F; Pomponi, MG; Scalise, A; Silvestri, G | 1 |
| Anderson, GD | 1 |
| David, J; Joseph, S; Joseph, T | 1 |
| Fukuhara, N; Ishida, C | 1 |
| Alkadhi, KA; Otoom, SA | 1 |
| Higashima, M; Ohno, K | 1 |
| Desiena, G; Lensu, S; Malmberg-Aiello, P; Tuomisto, L | 1 |
| Bílková, E; Haugvicová, R; Kubová, H; Mares, P | 1 |
| Rekling, JC | 1 |
| Jevtovic-Todorovic, V; Rastogi, AJ; Todorovic, SM | 1 |
| LIVINGSTON, S | 1 |
| HENSON, RA | 1 |
| BAIRD, HW | 1 |
| KIORBOE, E; OVERVAD, E; PALUDAN, J; TROLLE, E | 1 |
| CURRIER, RD | 1 |
| FREY, HH | 1 |
| CRAIG, WS; MACKINNON, JM | 1 |
| Papp, Z; Török, L | 1 |
| Blanco, CC; Carretero, AS; Casas, MN; Gutiérrez, AF | 1 |
| Aujard, Y; Livet, MO; Ponsot, G | 1 |
| Castro-Alamancos, MA; Rigas, P; Tawara-Hirata, Y | 1 |
| Gilbert, TH; Teskey, GC | 1 |
| Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Takechi, K | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| DeLorenzo, RJ; Deshpande, LS; Nagarkatti, N; Sombati, S | 1 |
| Mula, M | 1 |
| Baum, L; Kwan, P; Zhang, C; Zuo, Z | 1 |
| Delorenzo, RJ; Deshpande, LS; Ziobro, JM | 1 |
| Aoto, T; Baulac, S; Boillot, M; Fumoto, N; Ikeda, A; Ishida, S; Kuwamura, M; LeGuern, E; Mashimo, T; Ohno, Y; Serikawa, T; Takahashi, R; Takizawa, A; Ueda, M | 1 |
| Bialer, M | 1 |
| Abdar, M; Mandegary, A; Sharififar, F | 1 |
| Lu, XC; Marcsisin, SR; Melendez, V; Mountney, A; Potter, B; Shear, DA; Sousa, J; Tortella, FC | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
44 review(s) available for phenytoin and ethosuximide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
The effect of anti-convulsant drugs on cognitive abilities.
Topics: Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Psychological Tests | 1979 |
Pharmacological and biochemical studies in epileptic fowl.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Brain; Chickens; Disease Models, Animal; Ethosuximide; Female; Humans; Male; Mutation; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Valproic Acid | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Pharmacological regulation of astrocytic calcium channels: implications for the treatment of seizure disorders.
Topics: Animals; Anticonvulsants; Astrocytes; Calcium; Calcium Channels; Cells, Cultured; Drug Design; Epilepsy; Ethosuximide; Humans; Ion Channel Gating; Mice; Phenytoin; Potassium Chloride; Signal Transduction | 1992 |
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monitoring; Epilepsy; Ethosuximide; Humans; Leukopenia; Phenytoin; Thrombocytopenia; Valproic Acid | 1991 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carbamazepine; Cerebellar Ataxia; Dystonia; Ethosuximide; Folic Acid Deficiency; Hormones; Humans; Mental Disorders; Nervous System Diseases; Peripheral Nervous System Diseases; Phenytoin; Rats; Tremor; Valproic Acid | 1985 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
Effects of different classes of antiepileptic drugs on brain-stem pathways.
Topics: Animals; Anticonvulsants; Baclofen; Brain Stem; Carbamazepine; Disease Models, Animal; Electroshock; Ethosuximide; Phenytoin; Reticular Formation; Valproic Acid | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Plasma levels of anticonvulsants.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Barbiturates; Blood Proteins; Carbamazepine; Child; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Liver; Phenytoin; Protein Binding; Spectrophotometry; Thiazines; Trimethadione | 1973 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
A basic approach to the understanding of seizures and the mechanism of action and metabolism of anticonvulsants.
Topics: Acetylcholine; Aminobutyrates; Anticonvulsants; Calcium; Cell Membrane Permeability; Depression, Chemical; Diazepam; Epilepsy; Ethosuximide; Humans; Membrane Potentials; Mephobarbital; Neural Inhibition; Neurons; Phenobarbital; Phenytoin; Primidone; Seizures; Stimulation, Chemical; Synapses; Synaptic Transmission | 1973 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Pharmacology of anticonvulsants.
Topics: Animals; Anticonvulsants; Child; Drug Interactions; Electroencephalography; Ethosuximide; Half-Life; Humans; Liver; Mephobarbital; Phenobarbital; Phenytoin; Primidone | 1972 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
Pharmacodynamic and pharmacokinetic measurements of antiepileptic drugs.
Topics: Anticonvulsants; Chromatography, Gas; Dose-Response Relationship, Drug; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Convulsions in children.
Topics: Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Myoclonus; Phenytoin; Seizures | 1968 |
Psychopharmacological aspects of antiepileptic treatment.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenytoin; Psychological Tests; Psychometrics; Psychotropic Drugs; Research Design; Sampling Studies; Thiazines; Valproic Acid | 1980 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Mental effects of antiepileptic medication: a review.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Mental Processes; Phenytoin; Psychomotor Performance; Psychoses, Substance-Induced; Serotonin; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
[Neurotoxicity of anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid | 1999 |
New antiepileptic drugs: molecular targets.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid | 2009 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
6 trial(s) available for phenytoin and ethosuximide
| Article | Year |
|---|---|
Discontinuation of antiepileptic drugs in children who have outgrown epilepsy: effects on cognitive function.
Topics: Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Epilepsy; Ethosuximide; Humans; Memory, Short-Term; Phenytoin; Psychomotor Performance; Reaction Time; Valproic Acid | 1990 |
Relation of laboratory evaluation to clinical effectiveness of antiepileptic drugs.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzazepines; Clinical Trials as Topic; Drug Tolerance; Electroencephalography; Electroshock; Epilepsy; Ethosuximide; Humans; Pentylenetetrazole; Phenobarbital; Phenytoin; Primidone; Seizures; Trimethadione; Urea | 1969 |
Controlled and comparative trials with valproate: United States.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Middle Aged; Phenytoin; Spasms, Infantile; United States; Valproic Acid | 1984 |
Renal tubular dysfunction following treatment with anti-epileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Ethosuximide; Humans; Infant; Kidney Function Tests; Kidney Tubules; Phenytoin; Valproic Acid | 1994 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Male; Middle Aged; Phenobarbital; Phenytoin | 1996 |
305 other study(ies) available for phenytoin and ethosuximide
| Article | Year |
|---|---|
2-Phenyl-3H-imidazo[4,5-b]pyridine-3-acetamides as non-benzodiazepine anticonvulsants and anxiolytics.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Binding, Competitive; Cerebral Cortex; gamma-Aminobutyric Acid; Imidazoles; Mice; Mice, Inbred ICR; Molecular Structure; Pyridines; Rats; Receptors, GABA-A; Seizures | 1991 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
Synthesis and anticonvulsant activity of 2-iminohydantoins.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Hydantoins; Male; Mice; Structure-Activity Relationship | 1991 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
Triazolines. 14. 1,2,3-Triazolines and triazoles, a new class of anticonvulsants. Drug design and structure-activity relationships.
Topics: Animals; Anticonvulsants; Electroshock; Mice; Seizures; Structure-Activity Relationship; Triazoles | 1988 |
Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy.
Topics: Amino Acids; Animals; Anticonvulsants; Epilepsy; Magnetic Resonance Spectroscopy; Male; Mice; Seizures; Stereoisomerism; Structure-Activity Relationship | 1987 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
Synthesis and evaluation of N-(phenylacetyl)trifluoromethanesulfonamides as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Body Weight; Cytochrome P-450 Enzyme System; Epilepsy; Mesylates; Mice; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidoreductases, O-Demethylating; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Design and synthesis of anticonvulsants from a combined phthalimide-GABA-anilide and hydrazone pharmacophore.
Topics: Anilides; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hydrazones; Male; Mice; Phthalimides; Rotarod Performance Test; Seizures; Structure-Activity Relationship | 2007 |
Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain.
Topics: Animals; Anticonvulsants; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.
Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Drug Design; Electroshock; Mice; Pentylenetetrazole; Quinazolinones; Rats; Thiadiazoles | 2008 |
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Semicarbazones; Structure-Activity Relationship; Touch | 2007 |
Synthesis and anticonvulsant activity of 4-(2-(2,6-dimethylphenylamino)-2-oxoethylamino)-N-(substituted)butanamides: a pharmacophoric hybrid approach.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Chemistry, Pharmaceutical; Drug Design; Ethanol; gamma-Aminobutyric Acid; Mice; Models, Chemical; Molecular Structure; Motor Activity; Neurons; Seizures; Structure-Activity Relationship | 2007 |
CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.
Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Drug Design; Male; Mice; Motor Activity; Quinazolinones; Rats | 2008 |
Design, synthesis, and anticonvulsant activity of N-phenylamino derivatives of 3,3-dialkyl-pyrrolidine-2,5-diones and hexahydro-isoindole-1,3-diones.
Topics: Administration, Oral; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Electroshock; Injections, Intraperitoneal; Injections, Subcutaneous; Isoindoles; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pilocarpine; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship | 2008 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Newer GABA derivatives for the treatment of epilepsy including febrile seizures: a bioisosteric approach.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Epilepsy; Fever; gamma-Aminobutyric Acid; Mice; Molecular Structure; Rats; Rats, Wistar; Seizures, Febrile | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.
Topics: Animals; Anticonvulsants; Drug Design; Electroconvulsive Therapy; Lethal Dose 50; Mice; Triazoles | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Synthesis, anticonvulsant and toxicity screening of newer pyrimidine semicarbazone derivatives.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Drug Synergism; Epilepsy; Liver; Mice; Nervous System; Pyrimidines; Semicarbazones | 2010 |
Combating oxidative stress in epilepsy: design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides.
Topics: Animals; Anticonvulsants; Antioxidants; Benzylidene Compounds; Drug Design; Electrons; Epilepsy; Male; Mice; Oxidative Stress; Quantum Theory; Semicarbazides | 2010 |
Synthesis and anticonvulsant activity of new 6-methyl-1-substituted-4,6-diazaspiro[2.4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Electroshock; Epilepsy; Heptanes; Male; Mice; Pentylenetetrazole; Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles: one more step towards establishing four binding site pharmacophoric model hypothesis for anticonvulsant activity.
Topics: Animals; Anticonvulsants; Binding Sites; Models, Molecular; Oxadiazoles; Rats; Semicarbazones | 2010 |
Design, synthesis, and anticonvulsant activity of new N-Mannich bases derived from spirosuccinimides and spirohydantoins.
Topics: Animals; Anticonvulsants; Electroshock; Hydantoins; Male; Mannich Bases; Mice; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Sodium Channels; Spiro Compounds; Succinimides | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogs.
Topics: Acetamides; Animals; Anticonvulsants; Boron Compounds; Cyclohexanes; Dose-Response Relationship, Drug; Electric Stimulation; Magnetic Resonance Spectroscopy; Male; Mice; Phthalimides; Rats; Spectrometry, Mass, Electrospray Ionization | 2011 |
Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 1: perhydropyrrole[1,2-a]pyrazines.
Topics: Animals; Anticonvulsants; Diketopiperazines; Electroshock; Epilepsy; Humans; Male; Mice; Models, Molecular; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Sodium Channel Blockers; Sodium Channels | 2011 |
Synthesis and anticonvulsant activity of new 1-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]pyrrolidine-2,5-diones.
Topics: Administration, Oral; Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Electroshock; Ethosuximide; Injections, Intraperitoneal; Mice; Molecular Structure; Motor Activity; Pentylenetetrazole; Phenytoin; Piperazines; Rats; Seizures; Structure-Activity Relationship; Succinimides; Time Factors | 2011 |
Synthesis and anticonvulsant activity of new N-Mannich bases derived from 5-cyclopropyl-5-phenyl- and 5-cyclopropyl-5-(4-chlorophenyl)-imidazolidine-2,4-diones.
Topics: Animals; Anticonvulsants; Imidazolidines; Male; Mannich Bases; Mice; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2011 |
Design, synthesis and antiepileptic properties of novel 1-(substituted benzylidene)-3-(1-(morpholino/piperidino methyl)-2,3-dioxoindolin-5-yl)urea derivatives.
Topics: Animals; Anticonvulsants; Electroshock; Epilepsy; Humans; Isatin; Male; Mice; Morpholinos; Piperidines; Rats; Rats, Wistar; Structure-Activity Relationship; Urea | 2011 |
Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Biological Assay; Electroshock; Heptanes; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Quinolines; Seizures; Spiro Compounds; Structure-Activity Relationship; Toxicity Tests | 2012 |
Design, synthesis and anticonvulsant activities of novel 1-(substituted/unsubstituted benzylidene)-4-(4-(6,8-dibromo-2-(methyl/phenyl)-4-oxoquinazolin-3(4H)-yl)phenyl) semicarbazide derivatives.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Neurotoxicity Syndromes; Quinazolinones; Rats; Seizures; Semicarbazides; Structure-Activity Relationship | 2012 |
Synthesis and anticonvulsant activity of new N-Mannich bases derived from 3-(2-fluorophenyl)- and 3-(2-bromophenyl)-pyrrolidine-2,5-diones. Part II.
Topics: Administration, Oral; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mannich Bases; Mice; Mice, Inbred Strains; Molecular Structure; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Succinimides | 2012 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity.
Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Binding Sites; Cyclohexenes; Disease Models, Animal; gamma-Aminobutyric Acid; Limonene; Monoterpenes; Oxadiazoles; Protein Binding; Rats; Seizures; Semicarbazones; Structure-Activity Relationship; Terpenes | 2013 |
Synthesis and biological properties of new N-Mannich bases derived from 3-methyl-3-phenyl- and 3,3-dimethyl-succinimides. Part V.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Male; Mannich Bases; Mice; Mutagenesis; Rats; Safety; Sodium Channels; Succinimides; Vibrio | 2013 |
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: a hybrid pharmacophore approach.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Seizures; Thiazoles; Thioamides | 2013 |
Design, synthesis and anticonvulsant properties of new N-Mannich bases derived from 3-phenylpyrrolidine-2,5-diones.
Topics: Administration, Oral; Animals; Anticonvulsants; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Drug Design; Electroshock; Humans; Male; Mannich Bases; Mice; Microsomes, Liver; Motor Activity; Pentylenetetrazole; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2013 |
Structure-activity relationships of the aromatic site in novel anticonvulsant pyrrolo[1,2-a]pyrazine derivatives.
Topics: Animals; Anticonvulsants; Male; Mice; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Status Epilepticus; Structure-Activity Relationship | 2013 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Anticonvulsant evaluation of clubbed indole-1,2,4-triazine derivatives: a synthetic approach.
Topics: Animals; Anticonvulsants; Brain; Chemistry Techniques, Synthetic; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Sodium Channels; Triazines | 2014 |
Design and synthesis of new of 3-(benzo[d]isoxazol-3-yl)-1-substituted pyrrolidine-2, 5-dione derivatives as anticonvulsants.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Electroshock; Isoxazoles; Mice; Molecular Structure; Motor Activity; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Succinimides | 2014 |
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2014 |
Design, synthesis and pharmacological evaluation of novel N-(2-(1, 1-dimethyl-5, 7-dioxo-4, 6-diazaspiro[2.4]heptan-6-yl)ethyl) sulfonamide derivatives as potential anticonvulsant agents.
Topics: Animals; Anticonvulsants; Cycloheptanes; Drug Design; Electroshock; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Molecular Structure; Seizures; Spiro Compounds | 2015 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Design, synthesis and biological activity of new amides derived from 3-methyl-3-phenyl-2,5-dioxo-pyrrolidin-1-yl-acetic acid.
Topics: Acetates; Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Pyrrolidines; Seizures | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids.
Topics: Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrrolidines; Seizures | 2016 |
Design, synthesis and anticonvulsant-analgesic activity of new
Topics: | 2017 |
Novel benzothiazole hydrazine carboxamide hybrid scaffolds as potential in vitro GABA AT enzyme inhibitors: Synthesis, molecular docking and antiepileptic evaluation.
Topics: Anticonvulsants; Hydrazines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2019 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Effect of sodium valproate on plasma protein binding of diphenylhydantoin.
Topics: Animals; Blood Proteins; Brain; Drug Interactions; Ethosuximide; In Vitro Techniques; Injections, Intraperitoneal; Male; Phenytoin; Protein Binding; Rats; Thiazines; Valerates; Valproic Acid | 1977 |
Use of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
The effect of phenytoin and ethosuximide on primidone metabolism in patients with epilepsy.
Topics: Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Gamma hydroxybutyrate in the monkey. II. Effect of chronic oral anticonvulsant drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosuximide; Haplorhini; Hydroxybutyrates; Levodopa; Macaca mulatta; Phenobarbital; Phenytoin | 1978 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Mechaism of neuromuscular blockade with some antiepileptic drugs.
Topics: Abdominal Muscles; Anesthetics, Local; Animals; Anticonvulsants; Cats; Diaphragm; Ethosuximide; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscles; Neuromuscular Blocking Agents; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Phenobarbital; Phenytoin; Rabbits; Rats; Trimethadione | 1976 |
Cyclic nucleotides in epileptic brain: effects of pentylenetetrazol on regional cyclic AMP and cyclic GMP levels in vivo.
Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclic GMP; Ethosuximide; Female; Hippocampus; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Seizures; Thalamus | 1977 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
[Atypical petit mal status. Case contribution on diagnostic difficulties].
Topics: Adult; Cerebral Ventricle Neoplasms; Diagnostic Errors; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Male; Phenytoin; Tomography, X-Ray Computed; Valproic Acid | 1977 |
Effects of antiepileptic drugs on thalamocortical excitability.
Topics: Animals; Bicuculline; Cats; Computers; Diazepam; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Motor Cortex; Phenytoin; Thalamus; Time Factors | 1977 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Seizures; Seizures, Febrile | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
Action of phenytoin, ethosuximide and of the carbidopa-L-dopa association in semi-chronic cobalt-induced epilepsy in the rat.
Topics: Animals; Carbidopa; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Ethosuximide; Hydrazines; Levodopa; Male; Phenytoin; Rats; Seizures | 1977 |
[Selected clinical aspects of routine monitoring of anticonvulsant concentrations in serum (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Chromatography, Gas; Drug Therapy, Combination; Ethosuximide; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin | 1977 |
Pharmacological prophylaxis against the development of kindled amygdaloid seizures.
Topics: Acetazolamide; Amygdala; Animals; Cats; Dexamethasone; Electric Stimulation; Ethosuximide; Phenobarbital; Phenytoin; Seizures | 1977 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
[Optimizing the therapeutic process in long-term antiepileptic therapy through the determination of drug levels in patients].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy; Epilepsy; Ethosuximide; Germany, East; Humans; Methods; Phenobarbital; Phenytoin | 1978 |
Serum phenytoin after Ethosuximide.
Topics: Child; Drug Therapy, Combination; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin | 1978 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Diseases of the central nervous system: Epilepsy.
Topics: Age Factors; Diazepam; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Meningitis; Phenobarbital; Phenytoin | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Lupus-scleroderma syndrome induced by ethosuximide.
Topics: Adolescent; Anemia; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic; Phenobarbital; Phenytoin; Prednisolone; Scleroderma, Systemic | 1975 |
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone | 1976 |
Anticonvulsant drug antagonism of delta9tetrahydrocannabinol-induced seizures in rabbits.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinol; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Dronabinol; Ethosuximide; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures; Time Factors | 1977 |
Simultaneous determination of anticonvulsant drugs by gas-liquid chromatography.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
Gas chromatographic on-column methylation technique for the simulataneous determination of antiepileptic drugs in blood.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Methylation; Phenobarbital; Phenytoin; Primidone | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadione; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione | 1976 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Anticonvulsant drug mechanisms. Phenytoin, phenobarbital, and ethosuximide and calcium flux in isolated presynaptic endings.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Ethosuximide; Female; In Vitro Techniques; Phenobarbital; Phenytoin; Procaine; Rabbits; Synaptosomes; Time Factors | 1976 |
Simultaneous quantitative gas-chromatographic analysis of ethosuximide, phenobarbitone, primidone and diphenylhydantoin.
Topics: Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Para-substituted N-acetyl-L(S)- and -D(R)-alpha-amino-N-phenylglutarimides. A structure-activity study of substituent effects on steroselective anticonvulsant activity.
Topics: Animals; Anticonvulsants; Ethosuximide; Male; Mice; Phenytoin; Piperidines; Piperidones; Seizures; Stereoisomerism; Structure-Activity Relationship; Trimethadione | 1976 |
Anticonvulsant drugs and mental symptoms: a review.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Schizophrenia | 1976 |
Clinical pharmacokinetics in infants and children.
Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline | 1976 |
Antinuclear antibodies and lupus-like syndromes in children receiving anticonvulsants.
Topics: Adolescent; Adult; Antibodies, Antinuclear; Anticonvulsants; Child; Child, Preschool; Ethosuximide; Female; Humans; Infant; Lupus Erythematosus, Systemic; Male; Mephenytoin; Phenobarbital; Phenytoin; Seizures; Succinimides; Trimethadione | 1976 |
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione | 1975 |
The adverse effect of anticonvulsant therapy on renal allograft survival. A preliminary report.
Topics: Adolescent; Anticonvulsants; Cadaver; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Kidney Transplantation; Phenobarbital; Phenytoin; Postoperative Complications; Transplantation, Homologous | 1976 |
Letter: Epanutin and isoniazid interaction.
Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin | 1975 |
Unconjugated hyperbilirubinemia. Physiologic evaluation and experimental approaches to therapy.
Topics: Adult; Albumins; Animals; Bilirubin; Crigler-Najjar Syndrome; Ethosuximide; Female; Gilbert Disease; Glutethimide; Hemolysis; Humans; Hyperbilirubinemia; Liver; Phenobarbital; Phenytoin; Phototherapy; Plasmapheresis; Rats; Seizures | 1975 |
Proceedings: Clinical pharmacokinetics of antiepileptic drugs. Quantitative variables of drug clearance used for the individual assessment of dosage regimens.
Topics: Anticonvulsants; Drug Interactions; Ethosuximide; Humans; Hydroxybutyrates; Phenobarbital; Phenytoin; Primidone | 1974 |
Chromosomes and anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cells, Cultured; Chromatids; Chromosome Aberrations; Chromosomes; Ethosuximide; Female; Humans; In Vitro Techniques; Phenytoin; Polyploidy; Pregnancy; Primidone | 1975 |
Drug interaction: diazoxide and diphenylhydantoin.
Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Combination; Ethosuximide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Injections, Intramuscular; Male; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Radioligand Assay; Seizures | 1975 |
Response of generalized penicillin epilepsy in the cat to ethosuximide and diphenylhydantoin.
Topics: Animals; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Penicillins; Phenytoin; Seizures | 1975 |
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Trimethadione | 1975 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
Interlaboratory variability in determination of plasma antiepileptic drug concentrations.
Topics: Anticonvulsants; Epilepsy; Ethosuximide; Humans; Laboratories; Phenobarbital; Phenytoin; Primidone; Quality Control; United States | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Inhibition of alloxan-induced hyperglycaemia by compounds of similar molecular structure.
Topics: Allantoin; Alloxan; Animals; Barbiturates; Blood Glucose; Caffeine; Ethosuximide; Hyperglycemia; Inositol; Male; Mice; Phenytoin; Structure-Activity Relationship; Theophylline; Uric Acid | 1992 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
[Pellagra in anticonvulsive therapy].
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Intellectual Disability; Pellagra; Phenytoin; Photosensitivity Disorders; Valproic Acid; Vitamins | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Substantia nigra regulates action of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Discriminative stimulus properties of phenytoin in the pigeon: determination via a cumulative dosing procedure.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Discrimination Learning; Dose-Response Relationship, Drug; Ethosuximide; Female; Phenytoin; Succinimides | 1990 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Salivary drug measurement: a cautionary tale.
Topics: Citrates; Citric Acid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenytoin; Saliva | 1986 |
Chronic effects of ethosuximide, phenytoin, clonazepam, and valproic acid on the delayed-matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Ethosuximide; Phenytoin; Psychomotor Performance; Time Factors; Valproic Acid | 1986 |
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid | 1986 |
Chronic effects of clonazepam, phenytoin, ethosuximide, and valproic acid on learning in pigeons as assayed by a repeated acquisition procedure.
Topics: Animals; Benzodiazepinones; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Drug Tolerance; Ethosuximide; Learning; Phenytoin; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Effect of anticonvulsants on human chromosomes. 2. In vitro studies.
Topics: Anticonvulsants; Chromosome Aberrations; Chromosomes, Human; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin | 1988 |
Audiogenic seizures in Wistar rats before and after repeated auditory stimuli: clinical, pharmacological, and electroencephalographic studies.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Female; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1988 |
Use of three probes to assess the influence of sex on hepatic drug metabolism.
Topics: Adult; Ethosuximide; Female; Humans; Kinetics; Liver; Male; Middle Aged; Phenytoin; Sex Factors; Theophylline | 1987 |
Your CE topic this month (No. 20). Antiepileptic pharmacotherapy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Nursing, Practical; Phenytoin | 1986 |
Kindling of audiogenic seizures in the rat.
Topics: Acoustic Stimulation; Animals; Carbamazepine; Electroencephalography; Ethosuximide; Female; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1987 |
Differentiation of alcohol and barbital physical dependence.
Topics: Animals; Barbital; Barbiturates; Diazepam; Ethanol; Ethosuximide; Male; Mice; Morphine; Naloxone; Pentylenetetrazole; Phenytoin; Substance Withdrawal Syndrome | 1986 |
Termination of absence status and suppression of inter-ictal bursts with phenytoin: case report.
Topics: Child; Electroencephalography; Ethosuximide; Female; Humans; Memory Disorders; Phenytoin; Status Epilepticus | 1986 |
Effect of stimulus intensity on the profile of anticonvulsant activity of phenytoin, ethosuximide and valproate.
Topics: Animals; Anticonvulsants; Bicuculline; Electroshock; Ethosuximide; Male; Mice; Pentylenetetrazole; Phenytoin; Picrotoxin; Seizures; Valproic Acid | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Effects of phenobarbital, clonazepam, valproic acid, ethosuximide, and phenytoin on the delayed matching-to-sample performance of pigeons.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Conditioning, Psychological; Dose-Response Relationship, Drug; Ethosuximide; Memory; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
[A case of drug-induced lupus].
Topics: Adult; Anticonvulsants; Carbamazepine; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic; Phenytoin | 1985 |
Effects of diphenylhydantoin and cholinergic agents on the neuronally isolated cerebral cortex.
Topics: Animals; Atropine; Cats; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Parasympathomimetics; Phenytoin; Physostigmine; Pilocarpine; Scopolamine; Seizures; Synaptic Transmission; Trimethadione | 1971 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
[Calcium metabolism during antiepileptic therapy].
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Antipsychotic Agents; Calcium; Calcium Isotopes; Creatinine; Diazepam; Drug Combinations; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenothiazines; Phenytoin; Piperazines; Primidone; Time Factors | 1973 |
Alkylation reactions of hydantoins and succinimides.
Topics: Alkylation; Animals; Anticonvulsants; Benzyl Compounds; Chemical Phenomena; Chemistry; Ethosuximide; Hydantoins; Magnetic Resonance Spectroscopy; Male; Mice; Nitro Compounds; Pentylenetetrazole; Phenytoin; Spectrophotometry, Infrared; Succinimides | 1973 |
The effect of certain drugs on the plasma protein binding of phenytoin.
Topics: Anticonvulsants; Aspirin; Binding Sites; Blood Proteins; Carbamazepine; Dialysis; Diazepam; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Temperature; Thiazines; Ultrafiltration | 1973 |
Specific H-bonding of glutarimides and hydantoins to derivatives of RNA bases in chloroform solution.
Topics: Bemegride; Chemical Phenomena; Chemistry; Chloroform; Cycloheximide; Ethosuximide; Glutethimide; Hydantoins; Pemoline; Phenobarbital; Phenytoin; Piperidines; Piperidones; Primidone; RNA; Spectrophotometry, Infrared; Thalidomide | 1973 |
Inhibition of bovine brain aldehyde reductase by anticonvulsant compounds in vitro.
Topics: Aldehyde Oxidoreductases; Amobarbital; Animals; Anticonvulsants; Barbiturates; Brain; Cattle; Ethosuximide; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isomerism; Kinetics; Mephobarbital; NADP; Pentobarbital; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Succinimides; Trimethadione | 1973 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Sources of error in the determination of phenytoin (Dilantin) by Svensmark & Kristensen's method.
Topics: Dicumarol; Epilepsy; Ethosuximide; Humans; Methods; Phenylbutazone; Phenytoin; Spectrophotometry | 1967 |
A neuropathological study of a case of petit mal epilepsy.
Topics: Adolescent; Basal Ganglia; Brain; Cerebellum; Cerebral Cortex; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Frontal Lobe; Hippocampus; Humans; Mesencephalon; Phenytoin; Thalamus | 1968 |
Determination of phenytoin in serum in the presence of barbiturates, sulthiame and ethosuximid by thin-layer chromatography.
Topics: Anticonvulsants; Barbiturates; Chromatography, Thin Layer; Ethosuximide; Indicators and Reagents; Methods; Phenytoin; Staining and Labeling; Thiazines | 1969 |
[Inheritance of spike-wave complexes and febrile seizures in three generations].
Topics: Adult; Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Fever; Genes, Dominant; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Time Factors | 1973 |
Absorption of anticonvulsants after jejunoileal bypass.
Topics: Adult; Anticonvulsants; Diazepam; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Obesity; Phenytoin; Postoperative Complications | 1974 |
Therapy of seizures in children.
Topics: Child; Diazepam; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Injections, Intramuscular; Injections, Intravenous; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Rectum; Seizures | 1974 |
[Outpatient therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Depression, Chemical; Drug Eruptions; Drug Hypersensitivity; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Leukopenia; Nausea; Outpatient Clinics, Hospital; Phenytoin; Pyrimidines; Pyrimidinones; Sleep; Vomiting | 1970 |
Drug treatment of convulsive disorders.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxazoles; Phenobarbital; Phenytoin; Primidone; Pyrrolidinones; Seizures; Trimethadione | 1972 |
The role of inhibitory pathways in petit mal epilepsy.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Cats; Cerebral Cortex; Electric Stimulation; Epilepsy, Absence; Ethosuximide; Maxillary Nerve; Neural Inhibition; Phenytoin; Synaptic Transmission; Trigeminal Nerve; Trimethadione | 1972 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Infant, Newborn; Male; Nitrazepam; Oxazoles; Phenytoin; Seizures; Succinimides; Trimethadione | 1970 |
Evaluation of a new convulsant for anticonvulsant screening.
Topics: Acetazolamide; Animals; Anticonvulsants; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Diazepam; Ethosuximide; Female; Male; Mice; Phenobarbital; Phenytoin; Pyrimidines; Thiazines; Trimethadione | 1967 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Psychoses, Substance-Induced; Thiazines | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
[Clinical experience with propericiazine or an adjuvant in the therapy of epileptic syndromes].
Topics: Adolescent; Adult; Drug Synergism; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Male; Middle Aged; Nitriles; Phenothiazines; Phenytoin; Piperidines; Tranquilizing Agents | 1968 |
Anticonvulsant drugs in idiopathic epilepsy.
Topics: Acetazolamide; Anticonvulsants; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Hydantoins; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome; Succinimides; Urea | 1970 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Phenobarbital; Phenytoin; Thiazines | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
The effects of some anticonvulsant drugs on cobalt-induced epilepsy.
Topics: Animals; Cobalt; Electroencephalography; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Frontal Lobe; Male; Phenobarbital; Phenytoin; Rats | 1973 |
A medical and social survey of 231 children with seizures.
Topics: Adolescent; Attitude to Health; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Employment; Encephalitis; Epilepsy; Epilepsy, Absence; Ethosuximide; Female; Greece; Humans; Infant; Intelligence; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures; Socioeconomic Factors | 1972 |
The simultaneous determination of multiple anticonvulsant drug levels by gas-liquid chromatography. Method and clinical application.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chromatography, Gas; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Methods; Methylphenidate; Phenobarbital; Phenytoin; Primidone | 1972 |
[Ambulatory extended care for the child with seizures].
Topics: Adolescent; Age Factors; Ambulatory Care; Child; Child, Preschool; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenytoin; Primidone; Skilled Nursing Facilities | 1973 |
Dependence of anticonvulsant drug action on central monoamines.
Topics: Animals; Anticonvulsants; Dopamine; Drug Interactions; Electroshock; Ethosuximide; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pentylenetetrazole; Phenobarbital; Phenytoin; Receptors, Drug; Seizures; Serotonin; Time Factors | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chromatography, Gas; Diazepam; Epilepsy; Ethosuximide; Female; Fetus; Growth Disorders; Humans; Hydantoins; Infant, Newborn; Mass Spectrometry; Mephobarbital; Meprobamate; Milk, Human; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Prochlorperazine; Prospective Studies; Substance Withdrawal Syndrome; Succinimides; Time Factors | 1974 |
Letter: GLC microdetermination of plasma anticonvulsant levels.
Topics: Anticonvulsants; Chromatography, Gas; Ethosuximide; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1974 |
Pharmacology for the pediatrician. Noncompliance contributing to apparent drug failure in status epilepticus.
Topics: Anticonvulsants; Benzodiazepinones; Child; Chlorobenzenes; Diazepam; Epilepsy; Ethosuximide; Female; Humans; Medical Records; Medication Errors; Nitro Compounds; Phenobarbital; Phenytoin; Primidone | 1974 |
Erythrocyte uptake and plasma binding of diphenylhydantoin.
Topics: Carbon Radioisotopes; Dialysis; Erythrocytes; Ethosuximide; Female; Hematocrit; Humans; Hydroxylation; Liver Cirrhosis; Male; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Protein Binding; Sulfamethoxypyridazine; Time Factors; Uremia | 1974 |
[Ethosuximide in treatment of petit mal epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Trimethadione | 1965 |
Self-induced seizures.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Eye Movements; Female; Humans; Light; Male; Middle Aged; Phenytoin; Seizures | 1966 |
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expression; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Skull; Time Factors | 1972 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; Infant; Mephobarbital; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Radiography; Rickets; Seizures; Time Factors; Trimethadione; Vitamin D | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
[Effect of phenytoin and ethosuximide on the convulsive action of 2,4-dimethylsulfolan].
Topics: Acoustic Stimulation; Animals; Cyclic S-Oxides; Electrodes, Implanted; Ethosuximide; Male; Motor Activity; Phenytoin; Photic Stimulation; Rats; Seizures; Thiophenes | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
Self-induced television epilepsy.
Topics: Adolescent; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Myoclonus; Phenytoin; Television; Trimethadione | 1971 |
Severe bradykinesia as a manifestation of toxicity to antiepileptic medications.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsy; Ethosuximide; Humans; Male; Mental Processes; Movement Disorders; Oxazoles; Phenytoin; Psychometrics; Pyrrolidinones; Speech | 1971 |
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; Hand; Humans; Knee; Male; Methylphenidate; Phenobarbital; Phenytoin; Primidone; Radiography; Rickets; Thioridazine; Time Factors | 1971 |
Anticonvulsant drugs and brain glucose.
Topics: Acetazolamide; Animals; Anticonvulsants; Blood Glucose; Brain Chemistry; Ethosuximide; Glucose; Guinea Pigs; In Vitro Techniques; Mathematics; Mice; Oligosaccharides; Phenobarbital; Phenytoin; Sodium; Xylose | 1971 |
Studies on electrically induced-seizures and their antagonism by anticonvulsants during neonatal development in the mouse.
Topics: Acetazolamide; Animals; Animals, Newborn; Anticonvulsants; Electric Stimulation; Ethosuximide; Mice; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1967 |
[The necessary dosis of antiepileptic drugs in epileptic children during their growth period].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Body Weight; Child; Child Development; Child, Preschool; Epilepsy; Ethosuximide; Female; Growth; Humans; Infant; Male; Oxyphenbutazone; Phenytoin; Primidone | 1968 |
A sequential screning test based on the running component of audiogenic seizures in mice, including reference compound PD50 values.
Topics: Acetazolamide; Animals; Anticonvulsants; Atropine; Chloral Hydrate; Chlordiazepoxide; Ethosuximide; Haloperidol; Hydroxybutyrates; Hypnotics and Sedatives; Meprobamate; Methods; Mice; Motor Activity; Orphenadrine; Phenobarbital; Phenytoin; Primidone; Sound | 1969 |
Interaction of amphetamine with anticonvulsant drugs. II. Effect of amphetamine on the absorption of anticonvulsant drugs.
Topics: Amphetamine; Animals; Anticonvulsants; Drug Antagonism; Drug Synergism; Electroconvulsive Therapy; Ethosuximide; Female; Male; Mice; Phenobarbital; Phenytoin | 1966 |
Diphenylhydantoin substrate induced difference spectra: inhibition by other anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Ethosuximide; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Spectrophotometry; Thiazines; Valproic Acid | 1980 |
Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Brain; Ethosuximide; gamma-Aminobutyric Acid; Glutamates; Male; Neurotransmitter Agents; Organ Specificity; Phenobarbital; Phenytoin; Rats; Taurine; Thiazines; Valproic Acid | 1981 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Metabolic interactions of phenytoin in the rat: effect of coadministration with the anticonvulsant drugs sodium valproate, sulthiame, ethosuximide or phenobarbital.
Topics: Animals; Anticonvulsants; Brain; Drug Interactions; Ethosuximide; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Thiazines; Valproic Acid | 1984 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Antiepileptic agents affect hypothalamic beta-endorphin concentrations.
Topics: Animals; Anticonvulsants; beta-Endorphin; Endorphins; Ethosuximide; Hypothalamus; Kinetics; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Substance P; Valproic Acid | 1984 |
Excitatory and depressant effects of delta 9-tetrahydrocannabinol and cannabidiol on cortical evoked responses in the conscious rat.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinoids; Cerebral Cortex; Convulsants; Dronabinol; Ethosuximide; Evoked Potentials; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Anticonvulsant sensitivity of absence seizures in the tottering mutant mouse.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Epilepsy, Absence; Ethosuximide; Genes, Recessive; Mice; Mice, Neurologic Mutants; Mutation; Phenobarbital; Phenytoin | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Male; Phenytoin; Valproic Acid | 1984 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Effect of anticonvulsant drugs on thalamo-cortical and hippocampo-cortical self-sustained after-discharges in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Electric Stimulation; Electroencephalography; Epilepsy; Ethosuximide; Hippocampus; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Thalamus; Valproic Acid | 1984 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Effects of anticonvulsants on learning: performance of pigeons under a repeated acquisition procedure when exposed to phenobarbital, clonazepam, valproic acid, ethosuximide and phenytoin.
Topics: Animals; Anticonvulsants; Clonazepam; Columbidae; Dose-Response Relationship, Drug; Ethosuximide; Learning; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Nonsedative regimens in the treatment of epilepsy.
Topics: Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenytoin; Seizures; Valproic Acid | 1983 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Epilepsy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Infant; Medical History Taking; Narcolepsy; Phenobarbital; Phenytoin; Physical Examination; Sleep Wake Disorders | 1984 |
Fetal exposure to anticonvulsant drugs. Detailed pathological study of a case.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Adult; Anticonvulsants; Brain; Cardiomegaly; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Microscopy, Electron; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Purkinje Cells | 1980 |
Statistical analysis of performance of a liquid chromatographic assay of anticonvulsants involving solvent-demixing extraction and reciprocal internal standardization.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1984 |
[Monitoring of antiepileptic therapy. A basis for the clinical use of plasma levels in the treatment of epilepsy].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
[Morphologic image of structures of the limbic system in rats after prolonged administration of antiepileptics].
Topics: Animals; Anticonvulsants; Ethosuximide; Female; Limbic System; Male; Phenytoin; Rats; Rats, Inbred Strains | 1983 |
Comparative study on the teratogenicity of some antiepileptics in the rat.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carbamazepine; Ethosuximide; Female; Phenytoin; Pregnancy; Rats | 1983 |
[Differential treatment of epilepsy patients].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin | 1980 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Effect of anticonvulsant drugs on inhibitory and excitatory pathways.
Topics: Animals; Carbamazepine; Cats; Electric Stimulation; Ethosuximide; Maxillary Nerve; Neural Pathways; Phenytoin; Time Factors; Valproic Acid | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Quantitative evaluation of anticonvulsant effects on penicillin-induced spike foci in cats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electroencephalography; Ethosuximide; Penicillins; Phenytoin; Seizures; Valproic Acid | 1981 |
Effect of anticonvulsant drugs on kainic acid-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Diazepam; Electroencephalography; Ethosuximide; Guinea Pigs; Hippocampus; Kainic Acid; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1982 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
A rapid procedure for the simultaneous estimation of the anticonvulsant drugs, ethosuximide, phenobarbitone, phenytoin, and carbamazepine in serum using high-pressure liquid chromatography.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Reports of two cases of autoimmune thyroiditis while receiving anticonvulsant therapy.
Topics: Adolescent; Autoantibodies; Autoimmune Diseases; Child; Ethosuximide; Female; Goiter; Humans; Phenobarbital; Phenytoin; Thyroiditis | 1983 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
[Reduction of biotin level as a possible factor in the mode of action of anticonvulsants (author's transl)].
Topics: Adult; Anticonvulsants; Biotin; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Female; Humans; Male; Phenytoin | 1982 |
Effect of antiepileptic drugs and an anticonvulsant on epileptiform activity induced by antibodies to ganglioside.
Topics: Action Potentials; Aminooxyacetic Acid; Animals; Anticonvulsants; Cobalt; Diazepam; Disease Models, Animal; Electroencephalography; Ethosuximide; Gangliosides; Immune Sera; Male; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Seizures | 1982 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
Systematic method of development in liquid chromatography applied to the determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Solubility; Temperature | 1981 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Flash-evoked afterdischarge in rat as a model of the absence seizure: dose-response studies with therapeutic drugs.
Topics: Acetazolamide; Animals; Dose-Response Relationship, Drug; Ethosuximide; Evoked Potentials; Male; Mephenytoin; Phenobarbital; Phenytoin; Photic Stimulation; Rats; Seizures; Trimethadione | 1980 |
[Panmyelopathy in combined epilepsy therapy using ethosuccimide, diphenylhydantoin, and phenobarbital in childhood].
Topics: Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Pancytopenia; Phenobarbital; Phenytoin | 1980 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Practical considerations in anticonvulsant therapy--Part 2.
Topics: Anticonvulsants; Benzodiazepines; Cost Control; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Patient Compliance; Patient Education as Topic; Pharmacists; Phenobarbital; Phenytoin; Primidone; Role; Valproic Acid | 1995 |
Effect of antiepileptic drugs on absence-like seizures in the tremor rat.
Topics: Animals; Anticonvulsants; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Ethosuximide; Female; Injections, Intraperitoneal; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Seizures; Time Factors; Trimethadione; Valproic Acid | 1995 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Factors affecting the determination of drugs and endogenous low molecular mass compounds in human serum by micellar electrokinetic capillary chromatography with direct sample injection.
Topics: Anticonvulsants; Blood Chemical Analysis; Buffers; Capillary Action; Chromatography; Ethosuximide; Humans; Kinetics; Micelles; Molecular Weight; Naproxen; Osmolar Concentration; Phenobarbital; Phenytoin; Primidone | 1994 |
A new chronic model of spontaneous nonconvulsive generalized seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Evoked Potentials; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Sodium Oxybate; Valproic Acid | 1993 |
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures | 1993 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs.
Topics: Acetone; Acetonitriles; Anticonvulsants; Biocompatible Materials; Carbamazepine; Cyanoacrylates; Diffusion; Drug Compounding; Drug Delivery Systems; Ethanol; Ethosuximide; Freeze Fracturing; Membranes, Artificial; Microscopy, Electron; Phenytoin; Poloxalene; Scattering, Radiation; Surface-Active Agents; Tissue Adhesives; Triglycerides | 1996 |
A combined cobalt and C-14 2-deoxyglucose approach to antiepileptic drug assessment.
Topics: Animals; Anticonvulsants; Antimetabolites; Autoradiography; Brain Chemistry; Cobalt; Deoxyglucose; Drug Implants; Epilepsy; Ethosuximide; Ketamine; Male; Phenytoin; Rats; Thalamus; Visual Cortex | 1996 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 9; Diagnostic Errors; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; Hodgkin Disease; Humans; Intellectual Disability; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Myoclonus; Phenytoin; Pseudolymphoma; Trisomy; Valproic Acid | 1996 |
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid | 1998 |
Epileptiform activity of veratridine model in rat brain slices: effects of antiepileptic drugs.
Topics: Action Potentials; Animals; Anticonvulsants; Convulsants; Ethosuximide; Hippocampus; Ion Channel Gating; Ion Transport; Phenytoin; Pyramidal Cells; Rats; Sodium; Sodium Channels; Valproic Acid; Veratridine | 2000 |
Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; GABA Antagonists; Hippocampus; Male; Neurons; Phenytoin; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley | 2002 |
Effect of some antiepileptic drugs on brain histaminergic systems in the rat.
Topics: Acetates; Amines; Animals; Anticonvulsants; Brain Chemistry; Cyclohexanecarboxylic Acids; Ethosuximide; Gabapentin; gamma-Aminobutyric Acid; Histamine; Methylhistamines; Phenytoin; Rats; Rats, Wistar | 2002 |
Effects of classical antiepileptics on thresholds for phenomena induced by cortical stimulation in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Electroencephalography; Electrophysiology; Epilepsies, Myoclonic; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers | 2003 |
ANTIEPILEPTIC DRUGS.
Topics: Acetazolamide; Amphetamine; Amphetamines; Anticonvulsants; Barbiturates; Bromides; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Meprobamate; Phenobarbital; Phenytoin; Primidone; Succinimides; Toxicology | 1963 |
ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1964 |
CONVULSIONS IN INFANCY AND CHILDHOOD.
Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Seizures; Spasms, Infantile; Temporal Lobe; Toxicology | 1963 |
ZARONTIN (ETHOSUXIMIDE) IN THE TREATMENT OF PETIT MAL AND RELATED DISORDERS.
Topics: Adolescent; Anticonvulsants; Biomedical Research; Child; Denmark; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Myoclonus; Oxyphenbutazone; Phenobarbital; Phenytoin; Pyrrolidinones; Seizures; Toxicology | 1964 |
HINTS ON SEIZURE MANAGEMENT.
Topics: Anticonvulsants; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Seizures; Toxicology | 1964 |
NOTE ON THE INTERACTIONS OF AMPHETAMINE WITH ANTICONVULSANT DRUGS.
Topics: Amphetamine; Amphetamines; Animals; Anticonvulsants; Electricity; Electroshock; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Mice; Pentylenetetrazole; Pharmacology; Phenobarbital; Phenytoin; Research; Seizures | 1964 |
CHILD CARE IN GENERAL PRACTICE. CONVULSIONS IN INFANCY AND CHILDHOOD. II.
Topics: Acetazolamide; Anticonvulsants; Bromides; Child; Child Care; Chloral Hydrate; Diagnosis; Drug Therapy; Electroencephalography; Epilepsy; Ethosuximide; Family Practice; General Practice; Hospitalization; Humans; Infant; Oxyphenbutazone; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Prognosis; Radiography; Seizures; Toxicology | 1965 |
TOLERANCE TO ANTICONVULSANT DRUGS.
Topics: Anticonvulsants; Drug Tolerance; Electroshock; Ethosuximide; Metabolism; Mice; Phenobarbital; Phenytoin; Research; Seizures; Sex; Toxicology | 1965 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
Simple and rapid micellar electrokinetic capillary chromatographic method for simultaneous determination of four antiepileptics in human serum.
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Ethosuximide; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Phenytoin; Primidone; Quality Control; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2004 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroencephalography; Epilepsies, Myoclonic; Ergocalciferols; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Radiography; Rare Diseases; Rickets; Valproic Acid | 1976 |
Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers.
Topics: Anesthetics, Local; Animals; Calcium Channel Blockers; Electrophysiology; Ethosuximide; Evoked Potentials; Excitatory Amino Acid Antagonists; In Vitro Techniques; Ion Channels; Magnesium; Mibefradil; Mice; Motor Cortex; Neocortex; Phenytoin; Potassium Channel Blockers; Potassium Channels; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Riluzole; Sodium Channel Blockers; Tetrodotoxin | 2007 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electromyography; Electroshock; Ethosuximide; Fructose; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors; Topiramate | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
The novel antiepileptic drug carisbamate (RWJ 333369) is effective in inhibiting spontaneous recurrent seizure discharges and blocking sustained repetitive firing in cultured hippocampal neurons.
Topics: Animals; Anticonvulsants; Carbamates; Cells, Cultured; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Ethosuximide; Hippocampus; Magnesium Deficiency; Neurons; Patch-Clamp Techniques; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2008 |
In vitro concentration dependent transport of phenytoin and phenobarbital, but not ethosuximide, by human P-glycoprotein.
Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Blood-Brain Barrier; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Rhodamine 123; Verapamil | 2010 |
An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges.
Topics: Action Potentials; Animals; Anticonvulsants; Cell Survival; Epilepsy; Ethosuximide; Glutamic Acid; Hippocampus; Nerve Net; Neurons; Neurotoxins; Organ Culture Techniques; Patch-Clamp Techniques; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Stroke | 2011 |
A rat model for LGI1-related epilepsies.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Reflex; Ethosuximide; Heterozygote; Homozygote; Humans; Intercellular Signaling Peptides and Proteins; Levetiracetam; Molecular Sequence Data; Mutation, Missense; Neurons; Phenytoin; Piracetam; Proteins; Rats, Mutant Strains | 2012 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Anticonvulsant effect of the essential oil and methanolic extracts of Zataria multiflora Boiss.
Topics: Animals; Anticonvulsants; Distillation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Ethosuximide; Injections, Intraperitoneal; Lamiaceae; Male; Methanol; Mice; Oils, Volatile; Pentylenetetrazole; Phenytoin; Phytotherapy; Plant Extracts; Plant Oils; Plants, Medicinal; Postural Balance; Rotarod Performance Test; Seizures; Sesame Oil; Solvents | 2013 |
Ethosuximide and phenytoin dose-dependently attenuate acute nonconvulsive seizures after traumatic brain injury in rats.
Topics: Animals; Anticonvulsants; Brain; Brain Injuries; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Head Injuries, Penetrating; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures | 2013 |