phenytoin has been researched along with diphenhydramine in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (53.85) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 12 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Sen, S; Sinha, N | 1 |
| Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Adaros, HL; Barboza, JJ; Fuenzalida, E; Furst, J; Oviedo, AM; Porras, C | 1 |
| Gralla, EJ; Hayden, DW; Mattsson, JL; Sabo, JP; Yochmowitz, MG | 1 |
| Borkenstein, M; Haidvogl, M | 1 |
| Banna, NR; Kurkjian, R | 1 |
| Cowdell, RH; Higgins, G; Sanderson, JH | 1 |
| Granatek, AP; Mihotic, MM; Prasad, VK | 1 |
| Araki, S; Kato, M | 1 |
| Hagihara, B; Ichikawa, Y; Yamano, T | 1 |
| Arnold, K; Gerber, N | 1 |
| Black, JA | 1 |
| Epstein, JH; Sams, WM | 1 |
| Hata, T; Kita, T; Murakami, T | 1 |
| Hutchins, DA; Rogers, KJ | 1 |
| Kato, M | 1 |
| Hinz, JE; Pisciotta, AV; Ziebert, AP | 1 |
| Lee, CC | 1 |
| Chiriboga, CA; Moss, W; Ojukwu, C | 1 |
| McDonnell, KP; Winn, RE | 1 |
| ROSEN, JA | 1 |
| BURNS, JJ | 1 |
| DUBOIS, KP; HIETBRINK, BE; YAM, KM | 1 |
| BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R | 1 |
| Hu, C; Hu, X; Qu, J; Yang, M; Yuan, F | 1 |
| Tiwari, N; Verma, R | 1 |
| Digby, G; Jalini, S; Taylor, S | 1 |
2 review(s) available for phenytoin and diphenhydramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine | 1964 |
37 other study(ies) available for phenytoin and diphenhydramine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Recovery from rabies in man.
Topics: Adrenocorticotropic Hormone; Antibodies, Viral; Betamethasone; Biperiden; Diazepam; Diphenhydramine; Female; Follow-Up Studies; Humans; Immunization, Secondary; Infusions, Parenteral; Middle Aged; Phenytoin; Rabies; Rabies Vaccines; Remission, Spontaneous; Thiamine; Vitamin B 12 | 1976 |
The effect of selected drugs on first-stage radioemesis in beagle dogs.
Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhydramine; Dogs; Drug Combinations; Perphenazine; Phenytoin; Radiation Injuries, Experimental; Scopolamine; Vomiting; X-Rays | 1979 |
Treatment of ingestion of diphenhydramine.
Topics: Diphenhydramine; Fever; Gastric Lavage; Humans; Infant; Male; Phenytoin; Physostigmine; Respiration, Artificial | 1978 |
A novel tremorigen antagonized by D-amphetamine.
Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam; Diphenhydramine; Ganglionic Stimulants; Histidine; Male; Mice; Oximes; Phenoxybenzamine; Phenytoin; Propranolol; Scopolamine; Thiophenes; Tremor; Trimethadione | 1975 |
Fatal poisoning with methaqualone and diphenhydramine.
Topics: Diphenhydramine; Female; Humans; Injections, Intramuscular; Methaqualone; Middle Aged; Paraldehyde; Phenytoin; Seizures; Spectrophotometry; Tranquilizing Agents | 1966 |
Physical compatibility and chemical stability of cephapirin sodium in combination with non-antibiotic drugs in large-volume parenteral solutions. II.
Topics: Acetamides; Aminophylline; Ascorbic Acid; Barbiturates; Bicarbonates; Calcium Chloride; Cephalosporins; Chemical Phenomena; Chemistry; Diphenhydramine; Drug Combinations; Drug Incompatibility; Drug Stability; Epinephrine; Ergonovine; Heparin; Hydrocortisone; Hydrogen-Ion Concentration; Metaraminol; Nitrofurantoin; Norepinephrine; Phenytoin; Pyridines; Solutions; Succinylcholine; Sulfadiazine; Sulfides; Sulfisoxazole; Thiopental; Vitamins; Warfarin | 1974 |
Paroxysmal kinesignenic choreoathetosis. Report of a case relieved by carbamazepine.
Topics: Adolescent; Athetosis; Carbamazepine; Diazepam; Dibenzazepines; Diphenhydramine; Female; Humans; Huntington Disease; Lactose; Phenobarbital; Phenytoin | 1969 |
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry | 1967 |
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine | 1968 |
Hepatitis with encephalitis: dystonic reactions from various drugs.
Topics: Amides; Anisoles; Benzoates; Child; Diphenhydramine; Encephalitis; Ethylamines; Hepatitis; Hepatitis A; Humans; Male; Myotonia; Phenytoin | 1973 |
The experimental production of drug phototoxicity in guinea pigs. I. Using sunlight.
Topics: Animals; Chlorothiazide; Chlorpromazine; Demeclocycline; Diphenhydramine; Guinea Pigs; Phenytoin; Photosensitivity Disorders; Plastics; Skin; Sunlight; Tetracycline | 1967 |
[Introduction of mass psychology of animals to pharmacology. 2. New screening method of drugs acting on the central nervous system].
Topics: Aminobutyrates; Amphetamine; Animals; Anticonvulsants; Behavior, Animal; Carbamates; Chlordiazepoxide; Chlorpromazine; Diphenhydramine; Imidazoles; Imipramine; Male; Mice; Phenobarbital; Phenytoin; Reserpine; Tranquilizing Agents | 1969 |
Physiological and drug-induced changes in the glycogen content of mouse brain.
Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circadian Rhythm; Diphenhydramine; Glucose; Glycogen; Hyperglycemia; Insulin; Male; Mice; Motor Activity; Nialamide; Phenytoin; Propranolol; Seizures; Temperature | 1970 |
[Case of tonic seizure].
Topics: Adult; Arm; Benzazepines; Diphenhydramine; Electroencephalography; Epilepsy; Humans; Injections, Intravenous; Leg; Male; Phenobarbital; Phenytoin; Seizures | 1970 |
Effect of chlorpromazine on DNA synthesis in a cell free system.
Topics: Aminopyrine; Animals; Aspirin; Chlorpromazine; Diphenhydramine; DNA; In Vitro Techniques; Liver; Liver Regeneration; Phenytoin; Rats; Subcellular Fractions; Thioridazine; Thymidine | 1965 |
Comparative pharmacologic responses to antihistamines in newborn and young rats.
Topics: Animals; Animals, Newborn; Brain; Chlorpheniramine; Diphenhydramine; Injections, Subcutaneous; Liver; Phenytoin; Rats | 1966 |
Phenytoin-induced movement disorder. Unilateral presentation in a child and response to diphenhydramine.
Topics: Child, Preschool; Diphenhydramine; Dyskinesia, Drug-Induced; Dystonia; Facial Muscles; Female; Hemiplegia; Humans; Mouth Diseases; Phenytoin; Status Epilepticus | 1994 |
Fatality secondary to massive overdose of dimenhydrinate.
Topics: Adult; Arrhythmias, Cardiac; Cardiopulmonary Resuscitation; Charcoal; Colon; Dimenhydrinate; Diphenhydramine; Dopamine; Drug Overdose; Female; Humans; Infarction; Lidocaine; Lorazepam; Nonprescription Drugs; Phenytoin; Status Epilepticus; Suicide | 1993 |
PAROXYSMAL CHOREOATHETOSIS. ASSOCIATED WITH PERINATAL HYPOXIC ENCEPHALOPATHY.
Topics: Adolescent; Asphyxia Neonatorum; Athetosis; Atropa belladonna; Birth Injuries; Brain; Brain Damage, Chronic; Child; Chorea; Diphenhydramine; Electroencephalography; Humans; Hypoxia-Ischemia, Brain; Infant, Newborn; Phenytoin; Radiography | 1964 |
PHARMACOLOGICAL AND TOXICOLOGICAL COMPOUNDS AS PROTECTIVE OR THERAPEUTIC AGENTS AGAINST RADIATION INJURY IN EXPERIMENTAL ANIMALS. 3. STUDIES ON THE TOXICITY AND MECHANISM OF ACTION OF MERCAPTOETHYLAMINE (MEA). QUART PROGR REP NO. 53.
Topics: Animals; Animals, Laboratory; Cysteamine; Cysteine; Diphenhydramine; Glutathione; Guinea Pigs; Mercaptoethylamines; Pentobarbital; Pharmacology; Phenytoin; Radiation Effects; Radiation Injuries; Radiation-Protective Agents; Rats; Research; Reserpine; Toxicology; Tripelennamine | 1964 |
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine | 1965 |
Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H(2)O(2).
Topics: Antipyrine; Biodegradation, Environmental; Diphenhydramine; Hydrogen Peroxide; Ibuprofen; Kinetics; Oxidation-Reduction; Pesticide Residues; Phenytoin; Photochemistry; Photolysis; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical | 2009 |
Phenytoin intoxication induced by Mandrax (methaqualone).
Topics: Anticonvulsants; Cerebellar Diseases; Diphenhydramine; Drug Combinations; Epilepsy; Humans; Male; Methaqualone; Phenytoin; Vestibulocochlear Nerve Diseases; Young Adult | 2012 |
Medication-induced acute dystonic reaction: the challenge of diagnosing movement disorders in the intensive care unit.
Topics: Antipsychotic Agents; Benzodiazepines; Brain; Diphenhydramine; Dyskinesia, Drug-Induced; Haloperidol; Humans; Intensive Care Units; Male; Middle Aged; Phenytoin; Status Epilepticus; Stroke; Tomography, X-Ray Computed | 2015 |