phenytoin and dicumarol

phenytoin has been researched along with dicumarol in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199030 (88.24)18.7374
1990's0 (0.00)18.2507
2000's2 (5.88)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Aoyama, R; Jones, JP; Rao, S; Rettie, A; Schrag, M; Trager, WF1
Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Birkett, DJ; Graham, GG; Pond, SM; Wade, DN1
Kutt, H2
Hansen, M; Kristensen, M; Siersbaek-Nielsen, K; Skovsted, L1
Swanson, PD1
Grille, W; Johnsen, K; Kolenda, KD1
Livingston, S; Pauli, LL; Pruce, I1
Damanhouri, Z; Gumbleton, M; Nicholls, PJ; Shaw, MA1
Glogner, P1
Bixler, TJ; Del Rio, AE; Rudman, D1
Dayton, PG; Perel, JM1
Passananti, GT; Vessell, ES1
Bixler, TJ; Hollins, B; Mosteller, RC; Rudman, D1
La Du, BN1
Jatlow, P1
Vesell, ES3
Kutt, H; Penry, JK1
Christensen, LK; Hansen, JM; Kristensen, M; Skovsted, L1
Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M1
Hansen, JM; Hansen, OE; Kristensen, M; Lund, V1
Estabrook, RW; Greim, H; Remmer, H; Schenkman, J1
Marver, HS; Schmid, R1
Lucas, BG1
Christensen, LK; Skovsted, L1
Evans, DA1
BURNS, JJ1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1

Reviews

10 review(s) available for phenytoin and dicumarol

ArticleYear
[Conditions for the occurrence of drug interactions during biotransformation].
    Medizinische Klinik, 1979, Jan-19, Volume: 74, Issue:3

    Topics: Biotransformation; Dicumarol; Digitoxin; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Ethanol; Glucuronosyltransferase; Half-Life; Humans; Oxygenases; Pentobarbital; Phenytoin; Salicylates

1979
Physiological and physicochemical bases of drug interactions in man.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, Thin Layer; Deuterium; Dextrans; Dicumarol; Dogs; Drug Antagonism; Drug Synergism; Humans; Kinetics; Male; Metabolism; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Receptors, Drug; Salicylates; Stereoisomerism; Sulfinpyrazone; Sulfoxides; Thiopental

1971
Biochemical and genetic factors regulating dilantin metabolism in man.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines

1971
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays

1971
Pharmacogenetics: defective enzymes in relation to reactions to drugs.
    Annual review of medicine, 1972, Volume: 23

    Topics: Acetylation; Cholinesterases; Coumarins; Dicumarol; Dose-Response Relationship, Drug; Female; Genetic Code; Genetic Diseases, Inborn; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Male; Metabolism, Inborn Errors; Pharmacogenetics; Phenacetin; Phenobarbital; Phenytoin; Succinylcholine

1972
Advances in pharmacogenetics.
    Progress in medical genetics, 1973, Volume: 9

    Topics: Alcohol Oxidoreductases; Catalase; Cholinesterases; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Drug Resistance; Drug-Related Side Effects and Adverse Reactions; Environment; Female; Genetic Diseases, Inborn; Glaucoma; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Infant, Newborn; Intraocular Pressure; Isoniazid; Malignant Hyperthermia; Mutation; Pharmaceutical Preparations; Pharmacogenetics; Phenylthiourea; Phenytoin; Pregnancy; Protein Binding; Racial Groups; Warfarin

1973
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
Recent progress in pharmacogenetics.
    Advances in pharmacology, 1969, Volume: 7

    Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin

1969
Recent progress in pharmacogenetics.
    Advances in pharmacology and chemotherapy, 1969, Volume: 7

    Topics: Adult; Antipyrine; Cyanides; Dicumarol; Erythrocytes; Ethnicity; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Male; Middle Aged; Mutation; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Racial Groups; Taste; Twins

1969
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Trials

1 trial(s) available for phenytoin and dicumarol

ArticleYear
The effect of different oral anticoagulants on diphenylhydantoin (DPH) and tolbutamide metabolism.
    Acta medica Scandinavica, 1976, Volume: 199, Issue:6

    Topics: Coumarins; Dicumarol; Half-Life; Humans; Phenindione; Phenprocoumon; Phenytoin; Tolbutamide; Warfarin

1976

Other Studies

23 other study(ies) available for phenytoin and dicumarol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
A refined 3-dimensional QSAR of cytochrome P450 2C9: computational predictions of drug interactions.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Ligands; Models, Biological; Models, Molecular; Protein Binding; Reproducibility of Results; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Sulfaphenazole; Sulfonamides; Warfarin

2000
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Effects of tricyclic antidepressants on drug metabolism.
    Clinical pharmacology and therapeutics, 1975, Volume: 18, Issue:2

    Topics: Adult; Amitriptyline; Dicumarol; Half-Life; Humans; Kinetics; Male; Nortriptyline; Pharmaceutical Preparations; Phenytoin; Time Factors; Tolbutamide; Warfarin

1975
Interactions of antiepileptic drugs.
    Epilepsia, 1975, Volume: 16, Issue:2

    Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines

1975
Effects of beta-bungarotoxin, diphenylhydantoin and metabolic inhibitors on calcium uptake and on monovalent cations and high-energy phosphate contents of brain slices.
    Journal of neurochemistry, 1977, Volume: 29, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antimycin A; Bungarotoxins; Calcium; Cerebral Cortex; Dicumarol; Guinea Pigs; In Vitro Techniques; Phenytoin; Phosphates; Phosphocreatine; Potassium; Rotenone; Ruthenium Red

1977
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digitoxin; Drug Interactions; Female; Humans; Male; Oxacillin; Phenobarbital; Phenytoin; Pregnancy; Vitamin D

1979
In-vivo effects of itraconazole on hepatic mixed-function oxidase.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:2

    Topics: Animals; Anticonvulsants; Cytochrome P-450 Enzyme System; Dicumarol; Female; Itraconazole; Ketoconazole; Liver; Male; Mice; Mixed Function Oxygenases; Paralysis; Phenytoin; Rats; Tolbutamide

1988
[Unfavorable and problematic drug combinations. IV].
    Der Internist, 1970, Volume: 11, Issue:11

    Topics: Amphetamine; Ataxia; Bone Marrow; Cerebral Hemorrhage; Depression, Chemical; Dicumarol; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Ephedrine; Humans; Hypertension; Hypotension; Isoniazid; Mercaptopurine; Methamphetamine; Microsomes, Liver; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Phenytoin; Reserpine; Stimulation, Chemical; Thiazines; Thiopental; Tyramine

1970
Effect of free fatty acids on binding of drugs by bovine serum albumin, by human serum albumin and by rabbit serum.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:2

    Topics: Animals; Binding Sites; Blood; Caprylates; Dialysis; Dicumarol; Fatty Acids, Nonesterified; Humans; Phenylbutazone; Phenytoin; Protein Binding; Rabbits; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfadiazine; Sulfobromophthalein; Thiopental

1971
Transport of drugs, hormones and fatty acids in lipemic serum.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:3

    Topics: Adult; Aldosterone; Animals; Biological Transport; Caprylates; Centrifugation; Chickens; Cholesterol; Dicumarol; Digitoxin; Digoxin; Estradiol; Fatty Acids; Hormones; Humans; Hydrocortisone; Hyperlipidemias; Male; Pentobarbital; Pharmaceutical Preparations; Phenytoin; Protein Binding; Rabbits; Salicylates; Testosterone

1972
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
    American journal of clinical pathology, 1973, Volume: 59, Issue:2

    Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin

1973
Dicoumarol-induced diphenylhydantoin intoxication.
    Lancet (London, England), 1966, Jul-30, Volume: 2, Issue:7457

    Topics: Blood; Carbon Isotopes; Chromatography, Thin Layer; Dicumarol; Drug Synergism; Humans; Phenobarbital; Phenytoin

1966
Dose-dependence of drug plasma level decline in dogs.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K

1967
Sources of error in the determination of phenytoin (Dilantin) by Svensmark & Kristensen's method.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:4

    Topics: Dicumarol; Epilepsy; Ethosuximide; Humans; Methods; Phenylbutazone; Phenytoin; Spectrophotometry

1967
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2

    Topics: Aniline Compounds; Animals; Antipyrine; Benzopyrenes; Cytochromes; Dicumarol; Electron Transport; Enzyme Induction; Hexobarbital; Kinetics; Liver; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Prothrombin Time

1968
Biotransformation in the liver: implications for human disease.
    Gastroenterology, 1968, Volume: 55, Issue:2

    Topics: Animals; Biotransformation; Cytochromes; Dicumarol; Griseofulvin; Heme; Humans; Liver; Microsomes; Pharmaceutical Preparations; Phenytoin; Porphyrias; Rats

1968
"Dilantin" overdosage.
    The Medical journal of Australia, 1968, Oct-12, Volume: 2, Issue:15

    Topics: Aminosalicylic Acids; Anticonvulsants; Calcium; Dicumarol; Disulfiram; Drug Synergism; Drug Tolerance; Humans; Isoniazid; Lactose; Phenylbutazone; Phenytoin; Sulfaphenazole; Sulfates; Thiazines

1968
Inhibition of drug metabolism by chloramphenicol.
    Lancet (London, England), 1969, Dec-27, Volume: 2, Issue:7635

    Topics: Aged; Biotransformation; Carbon Isotopes; Chloramphenicol; Chromatography, Thin Layer; Dicumarol; Humans; Hypoglycemia; Male; Parkinson Disease; Phenytoin; Tolbutamide

1969
The hydroxylation of drugs- a pharmacogenetic problem?
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:2

    Topics: Antipyrine; Dicumarol; Endoplasmic Reticulum; Liver; Mixed Function Oxygenases; Nortriptyline; Pharmacogenetics; Phenylbutazone; Phenytoin

1970
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine

1965