phenytoin and debrisoquin

phenytoin has been researched along with debrisoquin in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (72.73)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (18.18)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Alván, G; Garle, M; Lind, M; Maguire, JH; McClanahan, JS; Nilson, SO; Sjöqvist, F; Steiner, E; Tomson, T	1
Bounameaux, Y	1
Eichelbaum, M	2
Roots, I	1
Fecycz, TD; Kadar, D; Kalow, W	1
Breimer, DD; Buruma, OJ; de Wolff, FA; Ferrari, MD; Vermeij, P	1
Idle, JR; Sloan, TP; Smith, RL	1
Hashimoto, Y; Hasunuma, M; Okabe, H	1

Reviews

1 review(s) available for phenytoin and debrisoquin

Article	Year
[Genetic polymorphism of oxidative drug metabolism. Therapeutic and toxicologic implications]. Der Internist, 1983, Volume: 24, Issue:3 Topics: Adrenergic beta-Antagonists; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Mephenytoin; Oxidation-Reduction; Perhexiline; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenotype; Phenytoin; Polymorphism, Genetic; Receptors, Drug; Sparteine	1983

Article

Year

[Genetic polymorphism of oxidative drug metabolism. Therapeutic and toxicologic implications].

Der Internist, 1983, Volume: 24, Issue:3

Topics: Adrenergic beta-Antagonists; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Mephenytoin; Oxidation-Reduction; Perhexiline; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenotype; Phenytoin; Polymorphism, Genetic; Receptors, Drug; Sparteine

1983

Other Studies

10 other study(ies) available for phenytoin and debrisoquin

Article	Year
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
The debrisoquin hydroxylation phenotype does not predict the metabolism of phenytoin. Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:3 Topics: Adult; Debrisoquin; Female; Humans; Hydroxylation; Isoquinolines; Kinetics; Male; Middle Aged; Phenotype; Phenytoin; Stereoisomerism	1987
[Studies on the effect of various substances on platelet function with several methods]. Die Medizinische Welt, 1973, Feb-02, Volume: 24, Issue:5 Topics: Amphetamine; Anti-Anxiety Agents; Blood Platelets; Caffeine; Chlorpromazine; Debrisoquin; Dibenzazepines; Flurazepam; Guanethidine; Humans; Oxazoles; Papaverine; Phenytoin; Platelet Aggregation; Pyridines; Theophylline	1973
Polymorphic drug oxidation in humans. Federation proceedings, 1984, May-15, Volume: 43, Issue:8 Topics: Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Debrisoquin; Humans; Mephenytoin; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenytoin; Polymorphism, Genetic; Sparteine; Tolbutamide	1984
[Genetic causes for the variability of effects and side effects of drugs]. Der Internist, 1982, Volume: 23, Issue:11 Topics: Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxylation; Kinetics; Male; Metabolism, Inborn Errors; Pharmaceutical Preparations; Pharmacogenetics; Phenytoin; Polymorphism, Genetic; Pregnancy; Twins	1982
The fate of orally administered [4-14C]phenytoin in two healthy male volunteers. Canadian journal of physiology and pharmacology, 1983, Volume: 61, Issue:4 Topics: Administration, Oral; Adult; Carbon Radioisotopes; Chromatography, Thin Layer; Debrisoquin; Humans; Male; Middle Aged; Phenytoin	1983
Impairment of phenytoin parahydroxylation as a cause of severe intoxication. Therapeutic drug monitoring, 1983, Volume: 5, Issue:2 Topics: Aged; Antipyrine; Debrisoquin; Humans; Hydroxylation; Kinetics; Male; Phenytoin	1983
Influence of DH/DL alleles regulating debrisoquine oxidation on phenytoin hydroxylation. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:4 Topics: Adult; Alleles; Debrisoquin; Female; Humans; Hydroxylation; Isoquinolines; Kinetics; Male; Oxidation-Reduction; Phenotype; Phenytoin	1981
The hepatic and intestinal metabolic activities of P450 in rats with surgery- and drug-induced renal dysfunction. Pharmaceutical research, 2003, Volume: 20, Issue:10 Topics: Animals; Cisplatin; Cytochrome P-450 Enzyme System; Debrisoquin; Glycerol; Hydroxylation; Hydroxytestosterones; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Nephrectomy; Phenytoin; Rats; Rats, Wistar; Renal Insufficiency	2003