phenytoin has been researched along with d-alpha tocopherol in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (44.44) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Clark, DR; Jenkins, WL | 1 |
| Mizoi, K; Yoshimoto, T | 1 |
| Bressieux, JM; Crampon, P; Fusade, T; Larrègue, M; Matard, B; Salhi, A | 1 |
| Arioni, C; Cipriani, C; Cozzani, E; Gnone, M | 1 |
| Amagasa, M; Mizoi, K; Ogawa, A; Yoshimoto, T | 1 |
| Imaizumi, S; Kinouchi, H; Suzuki, J; Yoshimoto, T | 1 |
| Abiko, H; Mizoi, K; Oba, M; Suzuki, J; Yoshimoto, T | 2 |
| Katayama, T; Kato, N; Kusuhara, T; Ohara, K; Ohchi, H | 1 |
| Amagasa, M; Mizoi, K; Suzuki, J; Yoshimoto, T | 1 |
| Boxall, LB; Haber, RM; Hanna, W; Ramsay, CA | 1 |
| Brotz, M; French, JH; Lubell, H; Moore, CL; Sherard, ES | 1 |
| Higashi, A; Ikeda, T; Matsuda, I; Matsukura, M | 1 |
| Kero, M | 1 |
| Eubanks, LE; Galen, W; McBurney, EI; Reed, R | 1 |
| Arita, K; Ikawa, F; Kitaoka, T; Kiya, K; Kurisu, K; Uozumi, T; Yuki, K | 1 |
| Ariyama, J; Furuno, H; Hirai, K; Koyama, J; Shimada, H; Simamura, E | 1 |
| Abela, D; Howe, AM; Oakes, DA; Webster, WS | 1 |
| Dubovický, M; Mach, M; Navarová, J; Ujházy, E | 1 |
| Dubovický, M; Kovacovský, P; Mach, M; Navarová, J; Ujházy, E | 1 |
| Augustijns, P; Froyen, L; Humbeeck, JV; Martens, JA; Van den Mooter, G; Van Eerdenbrugh, B; Vermant, J | 1 |
| Adedara, IA; Adeyemo, OA; Bakare, OS; Egun, C; Farombi, EO; Owoeye, O | 1 |
| Akpan, HD; Akpanabiatu, MI; Ekaidem, IS; Uboh, FE; Usoh, IF | 1 |
| Al-Khalek, HAA; Khalifa, AE; Masoud, SI; Nagib, MM; Rahmo, RM; Sabri, NA; Tadros, MG | 1 |
| Khalifa, AE; Masoud, SI; Nagib, MM; Rahmo, RM; Sabri, NA; Tadros, MG | 1 |
5 review(s) available for phenytoin and d-alpha tocopherol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
A review of drugs affecting the heart.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Calcium; Catecholamines; Cats; Digitalis Glycosides; Diuretics; Dog Diseases; Dogs; Glucagon; Heart; Heart Failure; Lidocaine; Liver; Myocardial Contraction; Phenytoin; Potassium; Propranolol; Prostaglandins; Quinidine; Vitamin E; Xanthines; Xylazine | 1977 |
[Epidermolysis bullosa and collagenoses].
Topics: Epidermolysis Bullosa; Humans; Microbial Collagenase; Phenytoin; Prognosis; Vitamin E | 1989 |
Hereditary epidermolysis bullosa.
Topics: Adult; Animals; Child; Child, Preschool; Chloroquine; Dogs; Epidermolysis Bullosa; Female; Humans; Infant; Infant, Newborn; Male; Phenytoin; Pregnancy; Prenatal Diagnosis; Retinoids; Sheep; Skin; Syndrome; Vitamin E | 1985 |
Linear scleroderma in children.
Topics: Administration, Topical; Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betamethasone; Child; Dermatologic Agents; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Penicillins; Phenytoin; Scleroderma, Localized; Ticlopidine; Vitamin E | 1996 |
22 other study(ies) available for phenytoin and d-alpha tocopherol
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Intraoperative monitoring of the somatosensory evoked potentials and cerebral blood flow during aneurysm surgery--safety evaluation for temporary vascular occlusion.
Topics: Brain Ischemia; Cerebrovascular Circulation; Drug Combinations; Evoked Potentials, Somatosensory; Humans; Intracranial Aneurysm; Intraoperative Complications; Mannitol; Monitoring, Intraoperative; Phenytoin; Vitamin E | 1991 |
[Epidermolysis bullosa herpetiformis of Dowling-Meara].
Topics: Child; Cicatrix; Epidermolysis Bullosa Simplex; Humans; Keratinocytes; Keratoderma, Palmoplantar; Male; Nail Diseases; Phenytoin; Vitamin E | 1990 |
Actions of brain-protecting substances against both oxygen and glucose deprivation in the guinea pig hippocampal neurons studied in vitro.
Topics: Action Potentials; Animals; Brain Ischemia; Electric Stimulation; Glucose; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Oxygen Consumption; Phenytoin; Vitamin E | 1989 |
[Superior protective activity of phenytoin against hypoxia in pharmacological screening test].
Topics: Animals; Atmosphere Exposure Chambers; Cerebral Infarction; Drug Evaluation, Preclinical; Hypoxia; Male; Mice; Pentobarbital; Phenytoin; Suloctidil; Vitamin E | 1986 |
[Protective effect of phenytoin and its enhanced action by combined administration of mannitol and vitamin E in cerebral ischemia].
Topics: Animals; Brain Edema; Brain Ischemia; Dogs; Drug Synergism; Electroencephalography; Injections, Intravenous; Mannitol; Phenytoin; Vitamin E | 1986 |
Protective effect of phenytoin and its enhanced action by combined administration with mannitol and vitamin E in cerebral ischaemia.
Topics: Animals; Brain Edema; Brain Ischemia; Dogs; Drug Therapy, Combination; Electroencephalography; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Mannitol; Phenytoin; Vitamin E | 1987 |
Effects of dietary xenobiotics on the metabolism of copper, alpha-tocopherol and cholesterol in rats.
Topics: Animals; Body Weight; Butylated Hydroxyanisole; Caffeine; Ceruloplasmin; Chlorobutanol; Cholesterol; Copper; DDT; Diet; Flavones; Flavonoids; Kidney; Liver; Male; Pharmaceutical Preparations; Phenytoin; Polychlorinated Biphenyls; Rats; Rats, Inbred Strains; Vitamin E | 1987 |
[Protective effect of various agents against ischemic neuronal damage in guinea pig hippocampal neurons studied in vitro].
Topics: Animals; Brain Ischemia; Dexamethasone; Guinea Pigs; Hippocampus; In Vitro Techniques; Mannitol; Microelectrodes; Neurons; Phenytoin; Vitamin E | 1988 |
Trichopoliodystrophy. I. Report of a case and biochemical studies.
Topics: Amino Acids; Brain Chemistry; Brain Diseases; Cerebellum; Cerebral Cortex; Cerebrosides; Cholesterol; Electroencephalography; Glycogen; Growth Disorders; Hair; Humans; Infant; Male; Nerve Degeneration; Pedigree; Phenobarbital; Phenytoin; Phospholipids; Plasmalogens; Seizures; Ubiquinone; Vitamin E | 1972 |
Serum zinc and vitamin E concentrations in handicapped children treated with anticonvulsants.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Disabled Persons; Humans; Phenobarbital; Phenytoin; Vitamin E; Zinc | 1982 |
Epidermolysis bullosa in Finland. Clinical features, morphology and relation to collagen metabolism.
Topics: Adolescent; Adult; Child; Child, Preschool; Collagen; Epidermolysis Bullosa; Female; Fibroblasts; Fibronectins; Finland; Genes, Dominant; Genes, Recessive; Humans; Hydroxychloroquine; Infant; Laminin; Male; Microbial Collagenase; Middle Aged; Pedigree; Phenytoin; Proteoglycans; Vitamin E | 1984 |
[Multivariate analysis of intentional temporary vessel occlusion in aneurysmal surgery].
Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Cerebral Arteries; Constriction; Female; Humans; Intracranial Aneurysm; Male; Mannitol; Middle Aged; Multivariate Analysis; Phenytoin; Postoperative Complications; Retrospective Studies; Risk Factors; Time Factors; Tocopherols; Vascular Surgical Procedures; Vitamin E | 1998 |
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E | 2002 |
Maternal antioxidant supplementation does not reduce the incidence of phenytoin-induced cleft lip and related malformations in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Antioxidants; Ascorbic Acid; Body Weight; Cleft Lip; Coenzymes; Diet; Eating; Female; Male; Maxilla; Phenytoin; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Ubiquinone; Vitamin E | 2005 |
Phenytoin induced oxidative stress in pre- and postnatal rat development - effect of vitamin E on selective biochemical variables.
Topics: Acetylglucosaminidase; Animals; Animals, Newborn; Anticonvulsants; Antioxidants; Female; Fetus; Oxidative Stress; Phenytoin; Pregnancy; Rats; Rats, Wistar; Vitamin E | 2005 |
Vitamin E supplementation in phenytoin induced developmental toxicity in rats: postnatal study.
Topics: Animals; Animals, Newborn; Dietary Supplements; Female; Fetal Hypoxia; Fetal Viability; Growth and Development; Male; Phenytoin; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Protective Agents; Rats; Rats, Wistar; Reflex; Vitamin E | 2006 |
Solubility increases associated with crystalline drug nanoparticles: methodologies and significance.
Topics: Acetamides; Acetophenones; Chemistry, Pharmaceutical; Crystallization; Drug Stability; Excipients; Itraconazole; Light; Micelles; Nanoparticles; Naproxen; Nephelometry and Turbidimetry; Particle Size; Phenytoin; Polyethylene Glycols; Scattering, Radiation; Solubility; Suspensions; Vitamin E | 2010 |
Kolaviron and vitamin E ameliorate hematotoxicity and oxidative stress in brains of prepubertal rats treated with an anticonvulsant phenytoin.
Topics: Animals; Anticonvulsants; Antioxidants; Blood Cells; Brain; Flavonoids; Male; Oxidative Stress; Phenytoin; Rats; Rats, Wistar; Vitamin E | 2014 |
Urate synthesis and oxidative stress in phenytoin hepatotoxicity: the role of antioxidant vitamins.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Folic Acid; Liver; Oxidative Stress; Phenytoin; Rats, Wistar; Superoxides; Uric Acid; Vitamin E; Xanthine Oxidase | 2014 |
Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Antioxidants; Brain; Inflammation; Male; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Pentylenetetrazole; Phenytoin; Rats, Wistar; Seizures; Signal Transduction; Sirtuin 1; Ubiquinone | 2018 |
Ameliorative Effects of α-Tocopherol and/or Coenzyme Q10 on Phenytoin-Induced Cognitive Impairment in Rats: Role of VEGF and BDNF-TrkB-CREB Pathway.
Topics: alpha-Tocopherol; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Drug Therapy, Combination; Male; Phenytoin; Rats; Rats, Wistar; Receptor, trkB; Signal Transduction; Treatment Outcome; Ubiquinone; Vascular Endothelial Growth Factor A | 2019 |