phenytoin and colchicine

phenytoin has been researched along with colchicine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's1 (3.70)18.2507
2000's5 (18.52)29.6817
2010's8 (29.63)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Al-Ach, NN; Al-Tel, TH; Alshihabi, AM; Anbar, HS; El-Awady, R; El-Gamal, MI; El-Gamal, R; Kalla, RR; Munther, MA; Sbenati, RM; Shahin, AI; Shehata, MK; Tarazi, H; Tokatly, RT; Wahba, MM; Zaraei, SO1
Lilly, MP; Mahany, TM; Raines, A; Spinola, SM1
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE1
Lee, SS; MacKinney, AA; Vyas, R1
Knobeloch, L; MacKinney, AA; Norback, D1
Friedman, GD1
Baba, A; Ishii, K; Iwata, H; Matsuda, T; Terashita, Z1
Cain, GD; Rahman, F1
Caratzali, A; Roman, IC1
Hynes, HE; Recker, RR1
Connolly, SM1
MacKinney, AA; Mueller, C; Vyas, R1
Pollack, SV1
Hurt, GM; Pento, JT; Rajah, T1
Biçer, S; Ctak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N1
Matsumoto, H; Ugawa, Y1

Reviews

3 review(s) available for phenytoin and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Current concepts in therapy: drug-induced malabsorption--a review.
    Southern medical journal, 1973, Volume: 66, Issue:6

    Topics: Aminosalicylic Acids; Calcium Carbonate; Cholestyramine Resin; Clofibrate; Colchicine; Contraceptives, Oral; Diuretics; Ethanol; Humans; Intestinal Absorption; Malabsorption Syndromes; Mannitol; Methotrexate; Phenytoin

1973
Scleroderma: therapeutic options.
    Cutis, 1984, Volume: 34, Issue:3

    Topics: Alprostadil; Captopril; Colchicine; Griseofulvin; Humans; Immunosuppressive Agents; Nifedipine; Penicillamine; Phenytoin; Physical Therapy Modalities; Plasmapheresis; Prostaglandins E; Scleroderma, Systemic; Vasodilator Agents

1984

Other Studies

24 other study(ies) available for phenytoin and colchicine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Hydroxyquinolines; Molecular Structure; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Quinolines; Sorafenib; Structure-Activity Relationship

2022
The effects of phenytoin and lidocaine on a proprioceptor of the cockroach, Blaberus discoidalis: a simple method for discriminating between inhibitors of sensory transduction and axonal conduction.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:2

    Topics: Action Potentials; Animals; Axons; Cockroaches; Colchicine; Lidocaine; Mechanoreceptors; Neural Conduction; Phenytoin; Sensation; Time Factors

1979
An effect of hyposmolarity on insulin release in vitro.
    The American journal of physiology, 1975, Volume: 228, Issue:3

    Topics: Amiloride; Amylases; Animals; Atropine; Calcium; Choline; Colchicine; Diazoxide; Epinephrine; Glucagon; Glucose; Hypotonic Solutions; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Male; Osmolar Concentration; Ouabain; Pancreas; Phentolamine; Phenytoin; Propranolol; Rats; Sorbitol; Tolbutamide; Trypsin Inhibitors; Vinblastine

1975
The effect of parahydroxylation of diphenylhydantoin on metaphase accumulation.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 149, Issue:2

    Topics: Cells, Cultured; Colchicine; DNA Replication; Humans; Lymphocytes; Mitosis; Mitotic Index; Phenols; Phenytoin; Protein Biosynthesis; Vincristine

1975
The effect of diphenylhydantoin and cortisol on the cell cycle.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 188, Issue:2

    Topics: Cell Cycle; Cells, Cultured; Colchicine; DNA; Flow Cytometry; Humans; Hydrocortisone; Interphase; Lymphocytes; Mitosis; Phenytoin; Phytohemagglutinins

1988
Multiple myeloma: relation to propoxyphene and other drugs, radiation and occupation.
    International journal of epidemiology, 1986, Volume: 15, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Colchicine; Dextropropoxyphene; Follow-Up Studies; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasms, Radiation-Induced; Occupations; Phenytoin

1986
Role of thiamine metabolism in the central nervous system. II. Effects of various agents on thiamine triphosphatase activity in rat brain.
    Japanese journal of pharmacology, 1974, Volume: 24, Issue:6

    Topics: Acetylcholine; Animals; Brain; Chlorpromazine; Colchicine; Fasting; In Vitro Techniques; Insulin; Liver; Male; Methamphetamine; Microsomes; Norepinephrine; Phenytoin; Phosphoric Acids; Phosphoric Monoester Hydrolases; Rats; Reserpine; Thiamine; Thiamine Deficiency; Tyramine

1974
[Action of diphenylhydantoin on chromosomes].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Jan-25, Volume: 272, Issue:4

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosomes; Colchicine; Culture Techniques; Embryo, Mammalian; Female; Fertility; Fetal Diseases; Infertility, Female; Lymphocytes; Mice; Mitosis; Phenytoin; Pregnancy; Rats

1971
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Adolescent; Adult; Aminosalicylic Acids; Anemia, Aplastic; Aspirin; Barbiturates; Child; Child, Preschool; Chloramphenicol; Chlorpropamide; Colchicine; Female; Glutethimide; Heparin; Humans; Infant; Isoniazid; Male; Middle Aged; Phenytoin; Riboflavin

1969
1-Acetyl-3-acetoxy-5'5-diphenylhydantoin has colchicine-like activity.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:2

    Topics: Animals; Binding, Competitive; Chromatography, Gel; Colchicine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lymphocytes; Metaphase; Microscopy, Electron; Microtubules; Mitotic Index; Phenytoin; Swine; Tubulin

1984
Wound healing: a review. IV. Systemic medications affecting wound healing.
    The Journal of dermatologic surgery and oncology, 1982, Volume: 8, Issue:8

    Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents; Cicatrix; Colchicine; Humans; Keloid; Medical History Taking; Mice; Penicillamine; Phenytoin; Rats; Skin Diseases; Sulfates; Vitamins; Wound Healing; Zinc; Zinc Sulfate

1982
Evaluation of calcium-mediated calcitonin secretion from the isolated perfused porcine thyroid using secretory inhibitors.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1995, Volume: 27, Issue:2

    Topics: Animals; Calcitonin; Calcium; Colchicine; Lidocaine; Phenytoin; Secretory Rate; Swine; Thyroid Gland

1995
Acute colchicine intoxication in a child: a case report.
    Pediatric emergency care, 2007, Volume: 23, Issue:5

    Topics: Acute Disease; Alopecia; Ataxia; Blood Transfusion; Case Management; Child, Preschool; Colchicine; Combined Modality Therapy; Disseminated Intravascular Coagulation; Dobutamine; Female; Fluid Therapy; Furosemide; Gastroenteritis; Humans; Hyponatremia; Hypotension; Multiple Organ Failure; Pancytopenia; Phenytoin; Poisoning; Seizures

2007
[Drug induced peripheral neuropathy].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-HIV Agents; Antibodies, Monoclonal; Anticonvulsants; Antineoplastic Agents; Antiprotozoal Agents; Antirheumatic Agents; Antitubercular Agents; Colchicine; Gout Suppressants; Humans; Immunosuppressive Agents; Infliximab; Interferon-alpha; Metronidazole; Peripheral Nervous System Diseases; Phenytoin; Tacrolimus

2012