phenytoin has been researched along with cocaine in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (21.43) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 7 (25.00) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM | 1 |
| Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Josephson, I; Sperelakis, N | 1 |
| Conway, EE; Mezey, AP; Powers, K | 1 |
| Kazama, K | 1 |
| Morita, M; Nagata, M; Sugimoto, J | 1 |
| Copeland, ES; Yang, GC | 1 |
| Miller, RH; Rushton, JG; Stevens, JC | 1 |
| Daras, M; Koppel, BS; Samkoff, L | 1 |
| Ganapathy, V; Leibach, FH; Mahesh, VB; Ramamoorthy, JD; Ramamoorthy, S | 1 |
| Hoffman, RS; Katz, AA; Silverman, RA | 1 |
| Crosby, RD; Eller, C; Graves, NL; Pearson, VL; Winegarden, T | 1 |
| Bliss, RL; Goldman, AI; Hatsukami, DK; Pentel, PR; Sofuoglu, M | 1 |
| Liebelt, EL; McElroy, EA; Shannon, M | 1 |
| Wiegand, T | 1 |
| Chernoff, N; Rogers, JM | 1 |
| Hantson, P; Wittebole, X | 1 |
| Degirmenci, E; Erdur, B; Ergin, A; Kortunay, S; Seyit, M; Yuksel, A | 1 |
| Roldan, CJ | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
| Chamberlain, JM; Coralic, Z; Kapur, J; Olson, KR; Overbeek, D; Silbergleit, R | 1 |
2 review(s) available for phenytoin and cocaine
| Article | Year |
|---|---|
Hypoxia and the Edema Syndrome: elucidation of a mechanism of teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Blister; Chick Embryo; Cocaine; Edema; Epinephrine; Hematoma; Hemorrhage; Hydroxyurea; Hypoxia; Phenytoin; Potassium Channel Blockers; Syndrome | 2010 |
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure.
Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Heavy Metal Poisoning; Humans; Lamotrigine; Liver Failure; Liver, Artificial; Metals, Heavy; Mushroom Poisoning; Phenytoin; Poisoning; Sorption Detoxification; Triazines | 2011 |
3 trial(s) available for phenytoin and cocaine
| Article | Year |
|---|---|
Phenytoin in the treatment of cocaine abuse: a double-blind study.
Topics: Adult; Anticonvulsants; Cocaine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Patient Compliance; Phenytoin; Substance-Related Disorders | 1996 |
Effects of phenytoin on cocaine self-administration in humans.
Topics: Adult; Analysis of Variance; Anticonvulsants; Cocaine-Related Disorders; Crack Cocaine; Female; Humans; Male; Middle Aged; Patient Dropouts; Phenytoin; Self Administration; Surveys and Questionnaires | 1999 |
Treatment of Toxin-Related Status Epilepticus With Levetiracetam, Fosphenytoin, or Valproate in Patients Enrolled in the Established Status Epilepticus Treatment Trial.
Topics: Adult; Alcoholism; Analgesics, Opioid; Anticonvulsants; Benzodiazepines; Child; Cocaine; Female; Humans; Levetiracetam; Male; Phenytoin; Prospective Studies; Seizures; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid | 2022 |
23 other study(ies) available for phenytoin and cocaine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Molecular characteristics for solid-state limited solubility.
Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility | 2008 |
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Local anesthetic blockade of Ca2+ -mediated action potentials in cardiac muscle.
Topics: Action Potentials; Anesthetics, Local; Animals; Calcium; Cells, Cultured; Chick Embryo; Cocaine; Heart; In Vitro Techniques; Lidocaine; Phenytoin; Procaine; Tetrodotoxin | 1976 |
Status epilepticus following the oral ingestion of cocaine in an infant.
Topics: Cocaine; Diagnosis, Differential; Diazepam; Electroencephalography; Emergencies; Humans; Infant; Male; Phenobarbital; Phenytoin; Status Epilepticus | 1990 |
[Effects of various pharmacological agents on neocortical seizure activities in the rabbit].
Topics: Aminobutyrates; Animals; Cerebral Cortex; Cocaine; Electric Stimulation; Electroencephalography; Evoked Potentials; Lidocaine; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rabbits; Strychnine | 1972 |
Comparative studies on the pharmacological actions of anti-arrhythmics in isolated guinea-pig atria.
Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Benzyl Compounds; Cocaine; Electric Stimulation; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Lidocaine; Male; Methyl Ethers; Phenytoin; Piperazines; Procainamide; Propranolol; Quinidine | 1973 |
Spin immunoassay.
Topics: Blood Proteins; Cocaine; Dronabinol; Electron Spin Resonance Spectroscopy; Humans; Immunoassay; Morphine; Narcotics; Pharmaceutical Preparations; Phenytoin; Progesterone; Saliva; Spin Labels | 1981 |
Glossopharyngeal (vagoglossopharyngeal) neuralgia: a study of 217 cases.
Topics: Adolescent; Adult; Carbamazepine; Cocaine; Cranial Nerve Diseases; Geniculate Ganglion; Glossopharyngeal Nerve; Humans; Middle Aged; Movement; Neuralgia; Pain; Phenytoin; Trigeminal Neuralgia | 1981 |
Phenytoin neurotoxicity from illicit use.
Topics: Adult; Crack Cocaine; Drug Interactions; Humans; Male; Neurotoxins; Phenytoin | 1995 |
Cocaine-sensitive sigma-receptor and its interaction with steroid hormones in the human placental syncytiotrophoblast and in choriocarcinoma cells.
Topics: Choriocarcinoma; Cocaine; Female; Giant Cells; Gonadal Steroid Hormones; Haloperidol; Humans; Ligands; Neuropeptide Y; Phenytoin; Placenta; Pregnancy; Receptors, sigma; Trophoblasts; Tumor Cells, Cultured; Uterine Neoplasms | 1995 |
Phenytoin toxicity from smoking crack cocaine adulterated with phenytoin.
Topics: Adult; Ataxia; Charcoal; Crack Cocaine; Drug Contamination; Gastric Lavage; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenytoin; Poisoning; Sleep Stages; Substance-Related Disorders | 1993 |
Toxic seizures in children: case scenarios and treatment strategies.
Topics: Adolescent; Camphor; Child, Preschool; Cocaine; Drug Interactions; Emergencies; Female; GABA Antagonists; Ginkgo biloba; Hexachlorocyclohexane; Humans; Infant; Insecticides; Isoniazid; Male; Phenytoin; Pyridines; Seeds; Seizures; Suicide, Attempted; Tachycardia | 2003 |
Phenytoin is not successful in preventing cocaine-induced seizures: a response to the article, "Cocaine body packing in pregnancy".
Topics: Anticonvulsants; Cocaine; Crime; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Seizures | 2007 |
Effects of pretreatment with etomidate, ketamine, phenytoin, and phenytoin/midazolam on acute, lethal cocaine toxicity.
Topics: Animals; Cocaine; Disease Models, Animal; Etomidate; Ketamine; Mice; Midazolam; Phenytoin; Random Allocation; Rats; Seizures; Treatment Outcome | 2012 |
Phenytoin toxicity from cocaine adulteration.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Drug Contamination; Drug Interactions; Emergency Service, Hospital; Humans; Male; Phenytoin; Prevalence; United States | 2014 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |