Compounds > phenytoin

phenytoin and clomipramine

phenytoin has been researched along with clomipramine in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (22.22)	18.7374
1990's	1 (5.56)	18.2507
2000's	4 (22.22)	29.6817
2010's	8 (44.44)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Grahame-Smith, DG; Green, AR	2
Herzog, DB	1
Perman, E	1
Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S	1

Reviews

3 review(s) available for phenytoin and clomipramine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine. Nature, 1976, Apr-08, Volume: 260, Issue:5551 Topics: Animals; Brain; Clomipramine; Depression; Dopamine; Humans; Hydroxyindoleacetic Acid; Lithium; Models, Biological; Monoamine Oxidase Inhibitors; Motor Activity; Phenytoin; Rats; Serotonin; Synapses; Thyrotropin-Releasing Hormone; Tryptophan	1976
Pharmacotherapy of anorexia nervosa and bulimia. Pediatric annals, 1984, Volume: 13, Issue:12 Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs	1984

Trials

1 trial(s) available for phenytoin and clomipramine

Article	Year
Pharmacotherapy of anorexia nervosa and bulimia. Pediatric annals, 1984, Volume: 13, Issue:12 Topics: Amitriptyline; Anorexia Nervosa; Antidepressive Agents, Tricyclic; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Cyproheptadine; Double-Blind Method; Feeding and Eating Disorders; Feeding Behavior; Humans; Hyperphagia; Monoamine Oxidase Inhibitors; Phenytoin; Psychotropic Drugs	1984

Other Studies

15 other study(ies) available for phenytoin and clomipramine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
The effect of diphenylhydantoin on brain 5-hydroxytryptamine metabolism and function. Neuropharmacology, 1975, Volume: 14, Issue:2 Topics: Animals; Brain; Brain Chemistry; Clomipramine; Dihydroxyphenylalanine; Drug Synergism; Male; Monoamine Oxidase Inhibitors; Motor Activity; Phenytoin; Rats; Serotonin; Tranylcypromine; Tryptamines; Tryptophan	1975
[More and more tooth injuries are being reported to the Läkemedelsförsökring (Drug Reaction Reporting System)]. Lakartidningen, 1999, Apr-07, Volume: 96, Issue:14 Topics: Adverse Drug Reaction Reporting Systems; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Diazepam; Female; Humans; Male; Middle Aged; Phenytoin; Sweden; Tooth Injuries	1999
Interaction of injectable neurotropic drugs with the red cell membrane. Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:7 Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid	2014