phenytoin has been researched along with clofibrate in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (42.31) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 4 (15.38) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chung, EK; Deglin, JM; Deglin, SM | 1 |
| Azarnoff, DL; Gugler, R | 1 |
| Gibaldi, M | 1 |
| Azarnoff, DL; Cohlmia, JB; Gugler, R; Huffman, DH; Shoeman, DW | 1 |
| Bershteĭn, LM; Bobrov, IuF; Dil'man, VM; Kovaleva, IG; Tsyrlina, EV | 1 |
| McQueen, EG | 1 |
| Dalton, C; Hope, HR; Hope, WC; Sheppard, H | 1 |
| Eipe, J | 1 |
| Cain, GD; Rahman, F | 1 |
| Rahn, KH | 1 |
| Abrams, WB; Reich, S; Solomon, HM; Spirt, N | 1 |
| Hirata, M; Nishibe, Y | 1 |
| Mock, DM; Mock, NI; Wang, KS | 1 |
| Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM | 1 |
| Hwang, JW; Hwang, SY; Jeon, KS; Jung, JW; Kang, JS; Kang, KS; Kim, YS; Lee, GJ; Lee, WS; Lee, YS; Li, P; Oh, MJ; Park, JE; Park, JS; Song, BS; Um, CH; Yeo, CD; Youn, JP | 1 |
6 review(s) available for phenytoin and clofibrate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug-induced cardiovascular diseases.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Antipsychotic Agents; Cardiovascular Diseases; Clofibrate; Contraceptives, Oral; Cyclophosphamide; Digitalis Glycosides; Doxorubicin; Estrogens; Humans; Hypoglycemic Agents; Lithium; Methysergide; Narcotic Antagonists; Narcotics; Phenothiazines; Phenytoin; Procainamide; Propranolol; Quinidine; Sympathomimetics | 1977 |
Drug protein binding and the nephrotic syndrome.
Topics: Antipyrine; Blood Proteins; Clofibrate; Diazepam; Half-Life; Humans; Kinetics; Nephrotic Syndrome; Pharmaceutical Preparations; Phenytoin; Prednisone; Protein Binding; Serum Albumin | 1976 |
Drugs affecting therapy with anticoagulants.
Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K | 1972 |
Current concepts in therapy: drug-induced malabsorption--a review.
Topics: Aminosalicylic Acids; Calcium Carbonate; Cholestyramine Resin; Clofibrate; Colchicine; Contraceptives, Oral; Diuretics; Ethanol; Humans; Intestinal Absorption; Malabsorption Syndromes; Mannitol; Methotrexate; Phenytoin | 1973 |
[Pharmacotherapy in chronic kidney failure].
Topics: Anti-Bacterial Agents; Antihypertensive Agents; Cardiac Glycosides; Clofibrate; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Humans; Kidney Failure, Chronic; Phenytoin; Protein Binding; Sulfonamides; Triamterene | 1974 |
20 other study(ies) available for phenytoin and clofibrate
| Article | Year |
|---|---|
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Drug distribution in renal failure.
Topics: Antipyrine; Clofibrate; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Kidney Failure, Chronic; Metabolic Clearance Rate; Nephrotic Syndrome; Pharmaceutical Preparations; Phenytoin; Protein Binding; Serum Albumin | 1977 |
Pharmacokinetics of drugs in patients with the nephrotic syndrome.
Topics: Adult; Antipyrine; Blood Proteins; Body Weight; Clofibrate; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Phenytoin; Protein Binding | 1975 |
[Correction of endocrine-metabolic disorders in oncologic patients. The effect of biguanides (phenformin and adebita), miskleron and diphenin].
Topics: Adrenal Cortex Hormones; Aged; Biguanides; Blood Glucose; Body Weight; Breast Neoplasms; Buformin; Cholesterol; Clofibrate; Colonic Neoplasms; Endocrine System Diseases; Fatty Acids; Female; Growth Hormone; Humans; Insulin; Lipoproteins; Lung Neoplasms; Middle Aged; Neoplasms; Phenformin; Phenytoin; Phospholipids; Triglycerides; Uric Acid; Uterine Neoplasms | 1975 |
Drug displacement from protein-binding and redistributional interactions.
Topics: Animals; Blood Proteins; Carboxylic Acids; Clofibrate; DDT; Dieldrin; Guanidines; Hexachlorocyclohexane; Humans; Kinetics; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Protein Binding; Rats; Sheep; Ultrafiltration; Warfarin | 1974 |
Relationship of serum triglyceride lowering to changes in hepatic composition induced by different classes of drugs.
Topics: Animals; Cholesterol; Clofibrate; Dactinomycin; DNA; Dose-Response Relationship, Drug; Glycolates; Hepatomegaly; Hypolipidemic Agents; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Nafenopin; Oxidoreductases, N-Demethylating; Phenobarbital; Phenyl Ethers; Phenytoin; Phospholipids; Piperazines; Piperidines; Propionates; Proteins; Rats; RNA; Spectrophotometry, Ultraviolet; Triglycerides | 1974 |
Interactions between digitoxin and other drugs in vitro and in vivo.
Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin | 1971 |
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases | 1995 |
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids | 1997 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Gene expression analysis of peroxisome proliferators- and phenytoin-induced hepatotoxicity using cDNA microarray.
Topics: Animals; Anticonvulsants; Chemical and Drug Induced Liver Injury; Clofibrate; Dose-Response Relationship, Drug; Gemfibrozil; Gene Expression Profiling; Gene Expression Regulation; Liver; Male; Oligonucleotide Array Sequence Analysis; Peroxisomes; Phenytoin; Rats; Rats, Sprague-Dawley | 2004 |