phenytoin has been researched along with carbamazepine in 1765 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 802 (45.44) | 18.7374 |
| 1990's | 437 (24.76) | 18.2507 |
| 2000's | 252 (14.28) | 29.6817 |
| 2010's | 217 (12.29) | 24.3611 |
| 2020's | 57 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Brahce, L; Gregor, VE; Lobbestael, SJ; Mayhugh, DR; Nugiel, D; Pavia, MR; Schwarz, RD; Taylor, CP; Vartanian, MG | 1 |
| Chang, H; Edafiogho, IO; Hinko, CN; Moore, JA; Mulzac, D; Nicholson, JM; Scott, KR | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Lobbestael, SJ; Pavia, MR; Taylor, CP | 1 |
| Brouillette, WJ; Brown, GB; DeLorey, TM; Grunewald, GL; Shirali, SS | 1 |
| Hino, K; Karasawa, T; Masuda, Y; Nagai, Y; Oka, M; Uno, H | 1 |
| Chapleo, CB; Myers, PL; Smith, AC; Tulloch, IF; Turner, S; Walter, DS | 1 |
| Chapleo, CB; Myers, M; Myers, PL; Saville, JF; Smith, AC; Stillings, MR; Tulloch, IF; Walter, DS; Welbourn, AP | 1 |
| Stillings, MR; Walter, DS; Welbourn, AP | 1 |
| Biziere, K; Brochard, J; Brodin, R; Chambon, JP; Hallot, A; Merlier, J | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Egawa, M; Fukami, H; Kikumoto, R; Ninomiya, K; Tobe, A | 1 |
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Bastide, P; Coudert, P; Couquelet, J; Gardette, D; Moreau, S; Rubat, C; Tronche, P; Vallee-Goyet, D | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Dimmock, JR; Hetherington, M; Lechler, T; Pugazhenthi, U; Puthucode, RN; Quail, JW; Smith, JM; Stables, JP | 1 |
| Almond, HR; Carmosin, RJ; Carson, JR; Pitis, PM; Stables, JP; Swinyard, EA; Vaught, JL; White, HS; Wolf, HH | 1 |
| Engel, J; Günther, R; Höfgen, N; Hofmann, HJ; Lankau, HJ; Liebscher, J; Menzer, M; Müller, B; Rolfs, A; Rostock, A; Unverferth, K | 1 |
| Bonsignori, A; Colombo, M; Dostert, P; Fariello, RG; Heidempergher, F; McArthur, RA; Pevarello, P; Pinciroli, V; Post, C; Salvati, P; Varasi, M | 1 |
| Cacciaguerra, S; Delarge, J; Depovere, P; Isa, M; Masereel, B; Poupaert, JH; Spampinato, S; Stables, JP; Ucar, H; Van derpoorten, K | 1 |
| Brouillette, WJ; Brown, GB; Brown, ML; Van Dyke, CC; Zha, CC | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Anger, T; Madge, DJ; Mulla, M; Riddall, D | 1 |
| Faller, B; Wohnsland, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Carter, RB; Gharagozloo, P; Hogenkamp, DJ; Ilyin, VI; Nguyen, P; Robledo, S; Woodward, RM; Yang, J; Yao, J | 1 |
| Chai, KY; Kwak, KC; Piao, HR; Quan, ZS; Xie, ZF | 1 |
| Pavana, RK; Raghavendran, JV; Sriram, D; Stables, J; Sudhan, K; Thirumurugan, R; Yogeeswari, P | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baltes, S; Fedrowitz, M; Gastens, AM; Kaever, V; Löscher, W; Potschka, H | 1 |
| Alam, M; Arshad, MF; Bhat, MA; Khan, SA; Pandeya, SN; Rana, A; Siddiqui, N; Stables, J | 1 |
| Cheikh, KE; Dogné, JM; Masereel, B; Montero, JL; Scozzafava, A; Supuran, CT; Thiry, A; Vullo, D; Winum, JY | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Jatav, V; Kashaw, S; Mishra, P; Stables, JP | 2 |
| Kavya, R; Nageswari, Y; Ragavendran, JV; Sreevatsan, N; Sriram, D; Stables, J; Vanitha, K; Yogeeswari, P | 1 |
| Gupta, A; Jatav, V; Kashaw, SK; Mishra, P; Stables, JP | 1 |
| Bhat, MA; Ehtaishamul Haque, S; Khan, SA; Rana, A; Siddiqui, N | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Guan, LP; Piao, HR; Piao, ZT; Quan, ZS; Zhao, LM | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Dogné, JM; Frankart, A; Masereel, B; Rolin, S; Scozzafava, A; Supuran, CT; Thiry, A; Vullo, D; Wouters, J | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Antkiewicz-Michaluk, L; Marona, H; Pekala, E; Szneler, E; Walczak, M | 1 |
| Gupta, A; Kashaw, SK; Kashaw, V; Mishra, P; Pandeya, SN; Stables, JP | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Cook, JM; Edwankar, CR; Edwankar, RV; Furtmüller, R; Huang, S; Jain, HD; Majumder, S; Murphree, L; Ramerstorfer, J; Rivas, FM; Roth, BL; Sankar, S; Sieghart, W; Stables, JP; Zhou, H | 1 |
| Brenneman, D; Cuyckens, F; Finley, MF; Herb, M; Huang, Y; Iannucci, R; Klein, B; Leclercq, L; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Jain, NK; Kashaw, SK; Kashaw, V; Mishra, P; Stables, JP | 1 |
| Amnerkar, ND; Bhusari, KP | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ahsan, W; Siddiqui, N | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Alkskas, IA; Azam, F; El-Gnidi, BA | 1 |
| Deng, XQ; Li, FN; Quan, ZS; Sun, ZG; Wei, CX | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Deshmukh, R; Kharya, MD; Mishra, P; Rajak, H; Sharma, AK; Veerasamy, R | 1 |
| Chawla, G; Kaushik, D; Khan, SA | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Sen, S; Sinha, N | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Deng, XQ; Quan, LN; Quan, ZS; Song, MX; Wei, CX | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Atamanyuk, D; Kamiński, K; Obniska, J; Wiklik, B | 1 |
| Marona, H; Pękala, E; Szneler, E; Walczak, M; Waszkielewicz, AM | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Babu, M; Pitchumani, K; Ramesh, P | 1 |
| Guo, H; He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Alagöz, MA; Calış, U; Dalkara, S; Karakurt, A; Sayoğlu, B | 1 |
| Amir, M; Hassan, MZ; Khan, SA | 1 |
| Kharya, MD; Raghuvanshi, K; Rajak, H; Sah, AK; Sharma, PC; Singh Pawar, R; Singh Thakur, B; Singh, A; Veerasamy, R | 1 |
| Bahare, RS; Khan, SA; Malik, S | 1 |
| Brenneman, DE; Finley, MF; Herb, M; Klein, BD; Liu, Y; Lubin, ML; Malatynska, E; Maryanoff, BE; McComsey, DF; Milewski, ME; Parker, MH; Qin, N; Reitz, AB; Smith-Swintosky, VL; White, HS; Wilcox, KS | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Kiyoshi, T; Miura, Y; Tanaka, T; Tanitame, A; Yajima, N | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Çalış, Ü; Dalkara, S; Karakurt, A; Kaynak, FB; Sari, S; Uslu, H | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chaudhary, S; Gupta, MK; Kaur, R; Kumar, K; Rawal, RK | 1 |
| Jamal Gilani, S; Kala, C; Prakash Dixit, S; Sarim Imam, S; Zaheen Hassan, M | 1 |
| Behnam, MAM; Bock, J; Graf, D; Klein, CD; Kühl, N; Leuthold, MM | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Behnam, MAM; Klein, CD; Kühl, N; Leuthold, MM | 1 |
| Bohlen, N; Hertl, M | 1 |
| Eadie, MJ; Lander, CM; Tyrer, JH | 2 |
| Brandt, S | 1 |
| Kaspar, U | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Richens, A | 3 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Clifford, JM | 1 |
| Callaghan, N; Duggan, PF; Feely, M; O'Callaghan, M | 1 |
| Driessen, OM; Goedhart, DM; Meijer, JW | 1 |
| Buchthal, A | 1 |
| Dittrich, P; Müller, E; Wutke, K | 1 |
| Eickhoff, K; Heipertz, R; Poser, W | 1 |
| Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Egli, M | 1 |
| Dodrill, CB; Wilkus, RJ | 1 |
| Mohrbacher, RJ; Riendeau, CJ; Werner, M | 1 |
| Flachs, H; Gram, L; Parnas, J | 2 |
| Cameron, JD; Hedley, DW | 1 |
| Kutt, H | 3 |
| Steele, DE | 1 |
| Fichsel, H; Knöpfle, G | 2 |
| Livingston, S; Pauli, LL; Pruce, I | 3 |
| Chih, JC; Felsher, BF; Larson, AW; Wasserstrom, WR | 1 |
| Penin, H | 1 |
| Deisenhammer, E; Sommer, R | 2 |
| Eeg-Olofsson, O | 1 |
| Ganes, T; Johannessen, SI; Rootwelt, K | 1 |
| Christiansen, J; Dam, AM; Dam, M; Hansen, BS; Kosteljanetz, M; Lyon, BB; Pedersen, H | 2 |
| Karasawa, T; Masuda, Y; Shimizu, M; Shiraishi, Y; Utsui, Y; Yoshida, K | 2 |
| Katz, RJ; Schmaltz, K | 1 |
| Lidgren, L; Nilsson, BE; Wallöe, A | 1 |
| Aucamp, AK | 1 |
| Myllylä, VV | 1 |
| Green, JR; Sato, M; Troupin, AS; Wada, JA; Wake, A | 1 |
| Afifi, AK; Baraka, AS; Harik, SI; Kronful, Z; Mire-Salman, J; Tomeh, GF | 1 |
| Bleck, V; Lewin, E | 1 |
| Meldrum, BS | 1 |
| Palmer, GC | 1 |
| Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
| Bayer, DB; Stenger, TG | 1 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Plaa, GL | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Glazko, AJ | 1 |
| Müller-Oerlinghausen, B | 1 |
| Stores, G | 1 |
| Bardy, A; Elomaa, E; Lehtovaara, R; Neuvonen, PJ | 1 |
| Poser, S; Poser, W; Ritter, G | 1 |
| Sauer, W; Windorfer, A | 1 |
| Hammond, KB | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 1 |
| Trompetter-van Woerden, ML; van der Zwan, A | 1 |
| Permin, H; Sestoft, L | 1 |
| Bicknell, PG; Gray, K; Rees, JR; Taylor, PH | 1 |
| Dodrill, CB; Troupin, AS | 2 |
| Aucamp, AK; Joubert, PH; Potgieter, GM; Verster, F | 1 |
| Oettinger, L | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 2 |
| Hori, M; Ito, T; Shimizu, M; Yoshida, K | 3 |
| Helenius, T; Liewendahl, K; Majuri, H | 1 |
| Karbowski, K | 2 |
| Dodrill, CB; Troupin, AS; Wilkus, RJ | 1 |
| Conomy, JP | 1 |
| Helmsing, PJ; van der Woude, J; van Eupen, OM | 1 |
| Göbel, W; Löscher, W | 1 |
| Fleetwood, JA; Mulligan, FA; Smith, PA | 1 |
| Christensen, NJ | 1 |
| Levy, RH; Patel, IH | 1 |
| Bruni, J | 3 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Newmark, ME; Penry, JK | 1 |
| Addy, DP | 1 |
| Andersen, B; Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Reith, H; Schäfer, H | 1 |
| Rylance, G | 1 |
| Curless, RG | 1 |
| Trimble, M | 1 |
| Valerio, P; Vizioli, R | 1 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fretthold, DW; Kumar, S; Pesh-Imam, M; Sunshine, I; Terrentine, S; Willis, CE | 1 |
| Harvey, CD; Sherwin, AL; Van Der Kleijn, E | 1 |
| Dodrill, C; Feigl, P; Friel, P; Halpern, L; Ojemann, LM; Troupin, A; Wilkus, R | 1 |
| Wada, JA | 1 |
| Hosokawa, K; Kugoh, T | 2 |
| Livingston, S | 1 |
| Swanson, PD | 1 |
| Stünkel, S; Windorfer, A | 1 |
| Goodey, RJ; Melding, PS | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Dymling, JF; Lidgren, L; Wallöe, A | 1 |
| Buckland, R; Hellekson, C; Price, T | 1 |
| Burk, PG; Nathanson, G; Pollack, MA | 1 |
| Galbraith, AW; Reynolds, EH; Shorvon, SD | 1 |
| von Albert, HH | 1 |
| Bäckström, T; Jorpes, P | 1 |
| Franks, RD; Richter, AJ | 1 |
| Fröscher, W | 2 |
| Mehta, PS | 1 |
| Rylance, GW | 1 |
| Jreissaty, S; Paulson, GW; Paulson, RB | 1 |
| Barron, SA; Heffner, RR | 1 |
| Kurata, K | 1 |
| Leuschner, U; Quednow, B; Walther, H | 1 |
| Eadie, MJ; McKauge, L; Tyrer, JH | 1 |
| Wilkinson, HA | 1 |
| Barragry, JM; Makin, HL; Scott, DF; Trafford, DJ | 1 |
| Davis, L; Drachman, DB; Jackson, DL; Satya-Murti, S | 1 |
| Abraham, CV; Gresham, D | 1 |
| Varma, R | 2 |
| Dalessio, DJ | 4 |
| Brauer, D; Wolter, M | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H; Seidel, D | 1 |
| Kaneko, S | 2 |
| Mercado, RM; Michelis, MF; Sagransky, DM; Sordillo, P | 1 |
| Chadwick, D; Galbraith, AW; Reynolds, EH; Shorvon, SD | 1 |
| de Zeeuw, RA; Oei, TT; van der Kleijn, E; Westenberg, HG | 1 |
| Loeser, JD | 3 |
| Plenge, KL | 1 |
| Köhler, E; Leuschner, U; Meyer, FP; Quednow, B; Walther, H | 1 |
| Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP | 1 |
| Rosenmund, H; Wad, N | 1 |
| Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ | 1 |
| Crunelli, V; Quattrone, A; Samanin, R | 1 |
| Hewitt, TE; Kessler, G; Sievers, DL | 1 |
| Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H | 1 |
| Christiansen, J; Friis, ML | 1 |
| den Hartog Jager, WA; Hootsmans, WJ | 1 |
| Christiansen, J; Friis, ML; Hvidberg, EF | 1 |
| Inoue, H; Mifune, J; Ohkawa, S; Sugiura, M; Takayanagi, K; Ueda, K | 1 |
| Alpert, JN | 1 |
| Perucca, E; Richens, A | 3 |
| Müller-Oerlinghausen, B; Riedel, E | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Kühl, V; Lund, M; Olsen, PZ; Simonsen, N; Wendelboe, J | 3 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Atzpodien, W; Bierbach, H; Denk, R; Haferkamp, G; Kremer, GJ; Schnellbacher, E | 1 |
| Atzpodien, W; Kremer, GJ | 1 |
| Gamstorp, I; Lilienberg, G; Norell, E | 1 |
| Freeman, JM; Singer, HS | 1 |
| Carruthers, R; Kutt, H; Louis, S; Peterson, H; Solomon, G; Wasterlain, C | 1 |
| Christiansen, J; Dam, M; Jensen, A | 1 |
| Corcoran, ME; Osawa, T; Sato, M; Troupin, AS; Wada, JA; Wake, A | 1 |
| Consroe, P; Eisenstein, D; Martin, P | 1 |
| Irani, PF; Purohit, AV; Wadia, NH | 1 |
| Pulsinelli, WA; Rottenberg, DA | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H | 1 |
| McElhatton, PR; Sullivan, FM | 1 |
| Johannessen, SI; Munthe-Kaas, AW; Strandjord, RE | 1 |
| Callaghan, N; Duggan, F; Feely, M; O'Callaghan, M; Seldrup, J | 1 |
| Brachet-Liermain, A; Centraud, B; Loiseau, P | 1 |
| Lewin, E | 1 |
| Guilleminault, C; Pedley, TA | 1 |
| Abraham, CV | 1 |
| Adams, RF; Vandemark, FL | 1 |
| Fellenberg, AJ; Pollard, AC | 1 |
| Dommasch, D; Glötzner, FL; Samland, O | 1 |
| Bertilsson, L; Eichelbaum, M; Lund, L; Palmér, L; Sjöqvist, F | 1 |
| Karmen, A; Lehrer, M | 1 |
| Benna, P; Covacich, A; Durelli, L; Fantini, M; Furlan, PM; Gerna, M; Gilli, M; Monaco, F; Morselli, PL; Mutani, R; Riccio, A; Troni, W | 1 |
| Kitazawa, S; Komuro, T | 1 |
| Cramers, CA; Hulsman, JA; Meijers, CA; van Kuik, LG; Vermeer, EA | 1 |
| Kitamura, M; Nishina, T; Okoshi, K | 1 |
| Hempel, E; Klinger, W | 1 |
| Herha, J; Obe, G | 1 |
| Abraham, CV; Joslin, HD | 2 |
| Reynolds, EH; Trimble, MR | 2 |
| Chadwick, D; Marsden, CD; Reynolds, EH | 1 |
| Rane, A; Wilson, JT | 1 |
| Murasaki, M | 1 |
| Danielson, MG; Fowler, GW; Julien, RM | 1 |
| Green, JR; Halpern, LM; Troupin, AS | 1 |
| Brock, JT; Cereghino, JJ; Penry, JK; Smith, LD; Van Meter, JC; White, BG | 2 |
| Johnson, J | 1 |
| Friel, P; Troupin, AS | 1 |
| Petruch, F; Schüppel, RV | 1 |
| Eadie, MJ | 3 |
| Johnson, GF; Least, CJ; Solomon, HM | 1 |
| Anlezark, G; Balzamo, E; Horton, RW; Meldrum, BS; Trimble, M | 1 |
| Meijer, JW; Meinardi, H; Van Der Kleijn, E; Van Rees, H | 1 |
| Dam, M; Kiørboe, E | 1 |
| Forbes, IJ; Sorrell, TC | 1 |
| Pisciotta, AV | 1 |
| Rodin, EA | 1 |
| Ojemann, LM; Troupin, AS | 1 |
| Gottschall, S; Gülzow, HU; Hein, J | 1 |
| Hill, JG; Soldin, SJ | 1 |
| Manford, M | 1 |
| Watanabe, M; Yagi, K | 1 |
| Chamadol, W; Thanaphaisal, C; Thangdamronggul, S | 1 |
| Bigarella, MM; Bittencourt, PR; Dóro, MP; Ferreira, ZS; Gorz, AM; Mader, MJ; Marcourakis, TM | 1 |
| Creger, RJ; Ghosh, C; Hewlett, JS; Lazarus, HM | 1 |
| Denning, DW; Graybill, JR; Hanson, LH; Pappagianis, D; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM | 1 |
| Eadie, MJ; Herkes, GK | 3 |
| Brodie, MJ; McKee, PJ; Percy-Robb, I | 1 |
| Richardson, SB; Twente, S | 1 |
| Aikiä, M; Halonen, T; Kälviäinen, R; Riekkinen, PJ; Sivenius, J | 1 |
| Chadwick, DW; Foy, PM; Johnson, AL; Rajgopalan, N; Shaw, MD | 1 |
| Patsalos, PN; Zakrzewska, JM | 1 |
| Morgenstern, E; Voigt, JP | 1 |
| Czuczwar, SJ; Kleinrok, Z; Roliński, Z; Wlaź, P | 1 |
| Leppik, IE | 4 |
| Huang, JD; Lai, ML; Lin, TS | 2 |
| Codd, EE; Shank, RP | 1 |
| Okamoto, M | 1 |
| Theodore, WH | 2 |
| Churchyard, A; Grainger, K; Khangure, M | 1 |
| Husag, L; Reber, M | 1 |
| Joshi, MV; Karande, SC; Kshirsagar, NA; Shah, PU | 1 |
| Baruzzi, A; Di Sarro, R; Gallassi, R; Lugaresi, E; Marra, M; Morreale, A | 1 |
| Bigler, S; Hänseler, E; Wad, N | 1 |
| Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W | 1 |
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| Cheymol, G; Lebot, M; Poirier, JM | 1 |
| Doré, C; Hudson, S; Wann, K; Wardley-Smith, B | 1 |
| Bittencourt, PR; Diekmann, HW; Fernandes, AG; Gracia, CM; Jung, W; Martins, R | 1 |
| Rainey, JE; Schaumann, BA; Taylor, K; Tittle, TV | 1 |
| Aspinall, P; Goldstein, LH; Lishman, WA; Patel, V | 1 |
| Friel, PN; McCormick, K; Yerby, MS | 1 |
| Lindhout, D; Meijer, JW; Meinardi, H; Nau, H | 1 |
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| Baba, A; Hori, T; Kawai, N; Koizumi, J; Moroji, T; Shiraishi, H; Suzuki, T; Tada, K | 1 |
| Schaumann, BA; Tittle, TV | 2 |
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| Fujita, M; Goto, S; Kida, M; Kubotsu, K; Matsuura, S; Sakurabayashi, I; Takano, S; Tuchiya, H | 1 |
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| Browne, TR; Burdette, D; Feldman, RG; Mikati, MA; Otis, J | 1 |
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| Catterall, WA; Macdonald, RL; McLean, MJ; Rock, DM; Taylor, CP | 1 |
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| Burns, EA; Gennis, MA; Hill, JV; Miller, MA; Spielberg, SP; Vemuri, R | 1 |
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| Burlina, A; Mould, GP; Müller, C; Stamp, RJ | 1 |
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| Berg, I; Butler, R; Forsythe, I; McGuire, R | 1 |
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| Heller, AJ; Johnson, AL; Marshall, WJ; Reynolds, EH; Ring, HA | 1 |
| Alonso, C; Camiña, MF; Gómez, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Cannon, PA; Drake, ME; Padamadan, H; Pakalnis, A; Weate, SM | 1 |
| Alonso, C; Camiña, MF; Castro-Gago, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H | 1 |
| Krumholz, A; Stern, BJ; Stern, EG | 1 |
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| Bates, SR; Hug, G; Landrigan, EA; McGraw, CA | 1 |
| Bertram, E; Cereghino, JJ; Dreifuss, FE; Drury, I; Graves, NM; Jacobs, MP; Leppik, IE; Pledger, GW; Santilli, N; Tsay, JY | 1 |
| Dupuis, RE; Miranda-Massari, J | 1 |
| Giardina, M; Pacifici, R; Paris, L; Pichini, S; Sideri, G; Zuccaro, P | 1 |
| Annesley, TM; Sackellares, JC; Schramm, W; Siegel, GJ; Smith, RH | 1 |
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| Beaudry, P; Chouinard, G; Sultan, S | 1 |
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| Holmes, GL | 1 |
| Mikati, M | 1 |
| Smith, DB | 1 |
| Foy, PM; Shaw, MD | 1 |
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| Bergfeldt, L; Kennebäck, G | 1 |
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| Browne, TR; Perchalski, RJ; Pylilo, RJ; Szabo, GK | 1 |
| Fukushima, Y; Hirano, T; Kaneko, S; Kondo, T; Otani, K | 1 |
| Altshuler, LL; Devinsky, O; Post, RM; Theodore, W | 1 |
| Cramer, JA; Hochholzer, JM; Mattson, RH; Scheyer, RD; Toftness, BR | 1 |
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| Modica, PA; Spitznagel, EL; Tempelhoff, R | 1 |
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| Chen, SS; Shen, MR | 1 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Acheampong, A; Anderson, GD; Baillie, TA; Friel, PN; Guyot, M; Levy, RH; Loiseau, P; Rettenmeier, AW; Tor, J; Wilensky, AJ | 1 |
| Peng, SM; Wu, JZ | 1 |
| Back, DJ; Chadwick, DJ; Crawford, P; Martin, C; Orme, M; Tjia, J | 1 |
| Heikkinen, ER; Pyhtinen, J; Rönty, HS; Tolonen, U | 1 |
| Shaw, MD | 1 |
| Fogel, BS; McNamara, ME | 1 |
| Foley, H | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
| Fromm, GH | 4 |
| Dawson, CM; Rainbow, SJ; Tickner, TR | 1 |
| Dimanico, U; Gianelli, M; Monaco, F; Mutani, R | 1 |
| Perrett, JE; Richens, A; Tsanaclis, LM; Williams, J; Wilson, JF | 1 |
| Paulsen, JS; Richardson, ED; Roberts, RJ; Varney, NR | 1 |
| Fromm, GH; Graff-Radford, SB; Sweet, WH; Terrence, CF | 1 |
| Cosgrove, M; Pople, S; Wallace, SJ | 1 |
| Kahn, D; Schneier, HA | 1 |
| Browne, TR; Dodson, WE; Dreifuss, FE; Engel, J; Leppik, IE; Mattson, RH; Nuwer, MR; Penry, J; Treiman, DM; Wilder, BJ | 1 |
| Ben-Dor, D; Grunwald, MH; Halevy, S; Livni, E | 1 |
| Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G | 1 |
| Elyas, AA; Patsalos, PN; Zakrzewska, JM | 1 |
| Bun, H; Cano, JP; Durand, A; Monjanel-Mouterde, S; Noel, F | 1 |
| Geiger, SA; Peuten, M | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R; Villagrán, R | 1 |
| Trimble, MR | 2 |
| Blennow, G; Heijbel, J; Sandstedt, P; Tonnby, B | 1 |
| Ruser, I | 1 |
| Brodie, MJ; Butler, E; Gillham, RA; Larkin, JG; Wiedmann, KD; Williams, N | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ichikou, N; Ieiri, I; Yamada, H | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ieiri, I; Yamada, H | 1 |
| Goldberg, VD; Hjelm, M; Ratnaraj, N | 2 |
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| Gallagher, BB; Huh, K; King, DW; Loring, DW; Meador, KJ | 1 |
| Goldbach, M; Phillips, MJ; Roberts, EA; Spielberg, SP | 1 |
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| Bardy, AH; Gaily, EK; Granström, ML; Hiilesmaa, VK | 1 |
| Friel, PN; Koerner, M; Leavitt, AM; McCormick, K; Sells, CJ; Van Allen, M; Yerby, JA; Yerby, MS | 1 |
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| Amin, I; Cooper, IS; Garnett, S; Nahmias, C; Springman, M; Upton, AR | 1 |
| Baraban, JM; Worley, PF | 1 |
| Burnham, WM; Mace, JA | 1 |
| Garcia de la Serrana, H; Mota, C; Puche, E; Saucedo, R | 1 |
| Schmidt, D | 7 |
| Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
| de la Peña, CA; Del Río, R; Fernandez, MP; Paz, JM; Rodriguez-Segade, S; Rozas, I; Tutor, JC | 1 |
| Büchsel, R; Kohl, D; Kreiten, K; Matern, S; Wietholtz, H; Zysset, T | 1 |
| Beastall, GH; Brodie, MJ; Larkin, JG; Macphee, GJ | 1 |
| Hasegawa, T; Johno, I; Kitazawa, S; Ohshima, T | 1 |
| Moore, FM; Simpson, D | 1 |
| Morrow, JI; Routledge, PA | 1 |
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| Garcia de la Serrana, H; Garcia Morillas, M; Mota, C; Puche, E | 1 |
| Cennamo, M; Piccione, E; Ticconi, C | 1 |
| Ebeid, MR; Feldman, S; Parker, P; Parks, B | 1 |
| Lajtha, A; Post, RM; Reith, ME; Weiss, SR; Zimányi, I | 1 |
| Logan, SD; McDermott, EE | 1 |
| Kater, SB; Mattson, MP | 1 |
| Franceschetti, S; Hamon, B; Heinemann, U; Konnerth, A; Yaari, Y | 1 |
| Catterall, WA; Gonoi, T; Willow, M | 1 |
| Kitteringham, NR; Park, BK; Riley, RJ | 1 |
| Eadie, MJ; Herkes, GK; McKinnon, GE | 1 |
| Privitera, MD | 1 |
| Martinez, C; Montini, C; Oliva, J; Ramirez, H | 1 |
| Dodson, WE | 2 |
| Pellock, JM | 1 |
| Cramer, JA; Mattson, RH; McCutchen, CB | 1 |
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| Knott, C; Reynolds, F | 2 |
| Bromfield, EB; Dambrosia, J; Devinsky, O; Nice, FJ; Theodore, WH | 1 |
| Ahuja, GK; Bag, S; Behari, M; Karmarkar, MG | 1 |
| Brown, WA; Fruzzetti, AE; Keitner, GI; Miller, IW; Norman, WH | 1 |
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| Chen, LS; Maltby, DA; McNamara, JO; Millington, DS | 1 |
| Albright, PS; Burnham, WM; Milgram, NW; Racine, RJ | 1 |
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| Morselli, PL | 1 |
| Iri, H; Kano, S; Kikuchi, H; Matsumoto, K; Takahashi, H; Umino, M | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Fortman, CS; Witte, DL | 1 |
| Macdonald, RL; McLean, MJ | 3 |
| Ashy, AR; el-Sayed, YM; Islam, SI | 1 |
| Higashi, A; Inotsume, N; Kinoshita, E; Matsuoka, T; Nakano, M | 1 |
| Eluma, FO; Hayes, TG; Sucheston, ME | 1 |
| Aldenhövel, HG | 2 |
| Cramarossa, L; D'Angelo, D; Galassi, A; Puletti, M | 1 |
| Herzog, AG; Levesque, LA; Seibel, MM | 1 |
| Ramsay, RE | 2 |
| Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
| Hartshorn, EA; Hartshorn, JC | 1 |
| Halonen, P; Lang, HA; Nyrke, T | 1 |
| Igarashi, T; Sakuraba, H; Suzuki, Y | 1 |
| DeLorenzo, RJ | 1 |
| Gilligan, BS; Harrison, PM; Horne, MK; Ioannides-Demos, LL; McLean, AJ; McNeil, JJ; Tong, N; Wodak, J | 1 |
| Graves, NM; Holmes, GB; Leppik, IE | 1 |
| Kishita, C | 1 |
| Canevini, MP; Canger, R; Cornaggia, CM; Giuccioli, D; Pruneri, C | 1 |
| Duncan, J | 1 |
| Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ | 1 |
| Buchanan, N | 1 |
| Brown, SW; McGowan, ME; Reynolds, EH | 1 |
| Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM | 1 |
| Callaghan, N; Casey, C; Goggin, T | 1 |
| Baker, M; Bissessar, A; Callaghan, N; Crowley, M; Goggin, T; Gough, H | 2 |
| Baciewicz, AM | 1 |
| Vaĭntrub, MIa | 1 |
| Lee, EK; Walters, JR; Waszczak, BL | 1 |
| Dam, M; Pedersen, B | 1 |
| Mondadori, C; Schmutz, M | 1 |
| Freed, WJ; Schwarz, SS | 1 |
| Ala-Houhala, M; Koivikko, M; Koivula, T; Korpela, R; Koskinen, M; Koskinen, T | 1 |
| Shinnar, S | 1 |
| Browning, RA; Faingold, CL | 1 |
| Bittencourt, PR; Gorz, AM; Silvado, CE | 1 |
| Bertollini, R; Källen, B; Mastroiacovo, P; Robert, E | 1 |
| Trimble, R | 1 |
| Ballinger, BR; Fenton, GW; Sheppard, LC | 1 |
| Dreifuss, FE; Langer, DH | 1 |
| Rangel, R; Wilder, BJ | 1 |
| Callaghan, N; Garrett, A; Goggin, T | 1 |
| Degen, HE; Degen, R; Kuhlmann, HP | 1 |
| de Voogd-van der Straaten, I; Neef, C | 1 |
| Borsey, DQ; Browning, MC; Connacher, AA; Davidson, DL; Jung, RT | 1 |
| Berger, S; Falk, J; Keating, A; Kelton, JG; Klein, M; McIlroy, WJ; Messner, H; Schweiger, FJ | 1 |
| Alexianu, M; Dan, A; Vasilescu, C | 1 |
| Baillie, TA; Boberg, M; Rettenmeier, AW; Rettie, AE | 1 |
| Campanella, G; Capone, D; De Marino, V; Del Rio, A; Pisanti, N | 1 |
| Krall, RL; Resor, SJ | 1 |
| Berlit, P; Krause, KH; Schellenberg, B; Schmidt-Gayk, H | 1 |
| Duncan, JS; Shorvon, SD; Trimble, MR | 1 |
| Lindhout, D; Reuss, A; Sachs, ES; Stewart, PA; van Swaay, E; Wladimiroff, JW | 1 |
| Bourgeois, BF | 3 |
| Hess, CW | 1 |
| Collins, JF; Cramer, JA; Mattson, RH | 1 |
| Campos Junior, Sda S; Damasceno, BP; de Melo-Souza, SE; Martins, LF | 1 |
| Bury, RW; Fullinfaw, RO; Kilpatrick, CJ; Moulds, RF | 1 |
| Shear, NH; Spielberg, SP | 1 |
| Chauhan, J; Dakshinamurti, K | 1 |
| Todman, DH | 1 |
| Reininghaus, R; Schmidt, D; Winkel, R | 1 |
| Debreczeni, LA; Herjavecz, I; Szeitz, A | 1 |
| Crawford, TO; Mitchell, WG | 1 |
| Bowman, T; Cloyd, J; Crosby, C; Dreifuss, FE; Graves, N; Jacobs, M; Leppik, IE; Porter, R; Santilli, N; Stackman, J | 1 |
| Dittmar, G; Lincke, HO | 1 |
| Collins, JF; Craft, B; Cramer, JA; Mattson, RH; Novelly, RA; Smith, DB | 1 |
| Borromei, A; Caramelli, R; Cipriani, G; Giancola, LC; Guerra, L; Lozito, A | 1 |
| Olsson, R; Zettergren, L | 1 |
| Maselli, RA; Rosenberg, RS; Spire, JP | 1 |
| Browne, TR; Evans, BA; Evans, JE; Greenblatt, DJ; Mikati, MA; Szabo, GK | 1 |
| Baruzzi, A; Gallassi, R; Lorusso, S; Lugaresi, E; Morreale, A; Procaccianti, G | 1 |
| Riad, LE; Sawchuk, RJ | 1 |
| Addae, JI; Stone, TW | 1 |
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| Brundage, RC; Cloyd, JC; Graves, NM; Leppik, IE; Welty, TE | 1 |
| Bittencourt, PR; Leite, PJ; Markourakis, T; Tsanaclis, LM | 1 |
| Guerreiro, CA; Guerreiro, MM; Silveira, DC | 1 |
| Schmidt, D; Utech, K | 1 |
| el-Sayed, YM; Islam, SI; Mira, SA | 1 |
| Spina, E; Tomson, T; Wedlund, JE | 1 |
| Haidukewych, D; Zielinski, JJ | 1 |
| Dodson, WE; Ferrendelli, JA; Hatlelid, JM; Morris, JC | 1 |
| Asberg, A; Haffner, F | 1 |
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| Berg, JD; Buckley, BM | 1 |
| Bartoszek, M; Brenner, AM; Szefler, SJ | 1 |
| Bhatia, MS; Kaur, N; Singhal, PK | 1 |
| Aman, MG; Field, CJ; Foote, SE; Paxton, JW | 1 |
| McGlone, R; Pritty, P | 1 |
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| Buchanan, RA; Friel, PN; Levy, RH; McLean, JR; Ojemann, LM; Shastri, RA; Wilensky, AJ | 1 |
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| Coulombe, RA; Hincks, JR; Margaretten, NC; Warren, RP | 1 |
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| Goldstein, JA | 1 |
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| Lowy, MT; Meltzer, HY | 1 |
| Gilligan, BS; Harrison, PM; Heinzow, U; Horne, M; Ioannides-Demos, LL; McLean, AJ; Tong, N; Wodak, J | 1 |
| Koskinen, T; Kuoppala, T; Tuimala, R | 1 |
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| Caron, G; Sheehan, M | 1 |
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| Arias, MJ | 1 |
| Kuhnz, W; Löscher, W; Nau, H | 1 |
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| Depaulis, A; Marescaux, C; Micheletti, G; Reis, J; Rumbach, L; Vergnes, M; Warter, JM | 1 |
| Levy, RH; Yerby, MS | 1 |
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| Dailey, JW; Jobe, PC | 1 |
| Browne, TR; Collins, JF; Cramer, JA; Delgado-Escueta, AV; Mattson, RH; McCutchen, CB; McNamara, JO; Smith, DB; Treiman, DM; Williamson, PD | 1 |
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| Ishizaki, T; Kushida, K | 1 |
| Burke, JT; Thénot, JP | 1 |
| Greene, SH; Lisk, DR | 1 |
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| Callaghan, N; Crowley, M; Goggin, T; Kenny, RA; O'Neill, B | 1 |
| Burgess, RJ; Drake, ME; Paulson, GW | 1 |
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| Haidukewych, D; John, G; Rodin, EA; Zielinski, JJ | 1 |
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| Brodie, MJ | 2 |
| Kaste, M; Muuronen, A; Nikkilä, EA; Tolppanen, EM | 1 |
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| May, T; Rambeck, B | 1 |
| Abbott, LC; Bennett, GD; Finnell, RH; Taylor, SM | 1 |
| Beran, RG; Lewis, JH; Nolte, JL; Westwood, AP | 1 |
| Duncan, JS; Sander, JW | 1 |
| Richter, K; Schmidt, D | 1 |
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| Hirayama, Y; Koide, Y; Moroka, K; Oka, S; Suzuki, H | 1 |
| Delafuente, JC | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Jones, MW; Levine, M; Sheppard, I | 1 |
| Cridland, JS | 1 |
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| Bertilsson, L; Ekbom, K; Sjöqvist, F; Tomson, T | 1 |
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| Haidukewych, D; Leheta, BJ; Zielinski, JJ | 1 |
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| Giacinto, J; Holmstrom, VL; Pritchard, PB; Roitzsch, JC | 1 |
| Pitterle, ME; Sorkness, CA; Wiederholt, JB | 1 |
| Durelli, L; Glorioso, N; Gusmaroli, G; Monaco, F; Mutani, R; Sechi, GP | 1 |
| Sie, O; Zwarts, MJ | 1 |
| Helenius, T; Liewendahl, K; Majuri, H; Tikanoja, S | 1 |
| Feldt-Rasmussen, U; Hansen, JM; Hegedüs, L; Kampmann, JP; Lühdorf, K; Perrild, H | 1 |
| Luoma, PV; Pelkonen, RO; Pirttiaho, HI; Sotaniemi, EA | 1 |
| DiMarzio, JM; Fisher, SJ; George, H; Horton, CM; Kurtz, SR | 1 |
| Feijoo, M; Goñi, M; Jimenez, M | 1 |
| Gormsen, H; Lund, A | 1 |
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| Davidson, S; Falconer, MA | 1 |
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| Hauswirth, O; Singh, BN | 1 |
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| Abbott, J; Bendtsen, L; Braschinsky, M; Cruccu, G; Di Stefano, G; Donnet, A; Eide, PK; Jensen, TS; Leal, PRL; Maarbjerg, S; May, A; Nurmikko, T; Obermann, M; Zakrzewska, JM | 1 |
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| Behdani, M; Ghezelayagh, Z; Ghorbanian, MT; Habibi-Anbouhi, M; Hajizadeh-Saffar, E; Kardoost, M; Pooshang Bagheri, K | 1 |
| A S, R; Baishya, J; Jose, M; Keni, RR; Sankara Sarma, P; Thomas, SV | 1 |
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| Asai, S; Imai, K; Kagawa, Y; Nishida, T; Shiratani, Y; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Ahn, KM; Chung, SJ; Oh, JH; Park, HW; Shim, JS | 1 |
| Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Carr, DF; Maggs, JL; Marson, AG; Meng, X; Park, BK; Pertinez, H; Pirmohamed, M; Yip, VLM | 1 |
| Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME | 1 |
| Cai, C; Chen, Y; Hu, X; Li, H; Ma, L; Xia, F; You, C | 1 |
| Banach, M; Borowicz-Reutt, KK | 1 |
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| Amagai, M; Fukasawa, T; Takahashi, H; Takahashi, K; Tanemura, N; Urushihara, H | 1 |
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| Douxfils, J; Hainaut, P; Hardy, M; Larock, AS; Lessire, S; Mullier, F; Sennesael, AL; Spinewine, A | 1 |
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| Chen, WW; Chien, MY; Chiou, MH; Chu, CY; Huang, PW | 1 |
| Barnhart, H; Björnsson, E; Bonkovsky, HL; Chalasani, N; Fontana, RJ; Gu, J; Hoofnagle, JH; Jacobsen, E; Kleiner, DE; Stine, JG | 1 |
| Adams, J; Carlson, JM; Dhillon, R; Holmes, LB; Janulewicz, PA; Macklin, EA; Phillips, C; Schomer, DL; Tosches, WA | 1 |
| Chen, C; Chen, X; Chi, L; Guo, X; Guo, Z; He, J; Liang, J; Wei, L; Ye, X; Zheng, Y; Zhou, W | 1 |
| Haen, E; Lipecki, Y | 1 |
| Chen, PY; Chen, TJ; Chiu, HY; Hsieh, SH; Lin, CJ; Luh, HT; Wang, BC; Wu, CR | 1 |
| Franco, V; Zaccara, G | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Agrawal, M; Dhurandhar, Y; Panda, SP | 1 |
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| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| LoPinto-Khoury, C | 1 |
| Banach, M; Borowicz-Reutt, K | 2 |
| Arima, R; Funakoshi, M; Ichikawa, N; Inoue, K; Maeda, R; Masuda, A; Obayashi, T; Sakaguchi, Y; Tsuchiya, Y | 1 |
| Chen, L; Duan, Y; He, Y; Kang, L; Li, M; Li, T; Wen, Z | 1 |
| Cates, AL; Greene, SC; Weiss, S; Wyatt, K | 1 |
| Bernat, P; Kołodziejczyk, P; Tutka, P; Zagaja, M; Łuszczki, JJ | 1 |
| Huang, Q; Liang, H; Lou, J; Tang, M; Xiang, D; Yin, T; Zhou, B | 1 |
| Bettinotti, M; Boldt, ABW; de Paola, L; Glehn, CQCV; Silvado, CES; Spina Tensini, T | 1 |
| Du, Y; Gong, J; Lin, J; Wang, X; Xia, N; Xu, H; Xu, Q; Zheng, R; Zhu, Z | 1 |
| Bojar, H; Chmielewski, J; Florek-Łuszczki, M; Jankiewicz, K; Skalicka-Woźniak, K; Łuszczki, JJ | 1 |
220 review(s) available for phenytoin and carbamazepine
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke | 2001 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recent synthetic and medicinal perspectives of dihydropyrimidinones: A review.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antinematodal Agents; Antineoplastic Agents; Antioxidants; Antiviral Agents; Heterocyclic Compounds; Humans; Pyrimidinones | 2017 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
[Diphenylhydantoin. Metabolism, pharmacokinetics, interactions and side effects].
Topics: Anti-Anxiety Agents; Benzodiazepines; Bone and Bones; Bone Marrow; Carbamazepine; Cerebellar Diseases; Cerebral Cortex; Digitalis Glycosides; Drug Antagonism; Drug Synergism; Epilepsy; Half-Life; Hirsutism; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kidney Failure, Chronic; Liver Diseases; Malabsorption Syndromes; Mutation; Phenytoin; Solubility | 1976 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
Drug disposition and effect in sub-human primates used in pharmacology.
Topics: Aldosterone; Amantadine; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Cholesterol; Cromolyn Sodium; Cyclophosphamide; Dogs; Estradiol; Haplorhini; Humans; Hydrocortisone; Hypnotics and Sedatives; Macaca fascicularis; Macaca mulatta; Papio; Pharmaceutical Preparations; Phenytoin; Primates; Progestins; Protein Binding; Saimiri; Testosterone; Uric Acid | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Trigeminal neuralgia: an overview.
Topics: Age Factors; Aged; Anesthetics, Local; Carbamazepine; Diagnosis, Differential; Electrocoagulation; Female; Humans; Male; Methods; Middle Aged; Multiple Sclerosis; Peripheral Nervous System Diseases; Phenytoin; Tooth Diseases; Trigeminal Nerve; Trigeminal Neuralgia | 1979 |
Acute toxicity of antiepileptic drugs.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Thiazines | 1975 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
Glossopharyngeal neuralgia with syncope.
Topics: Adult; Aged; Bradycardia; Carbamazepine; Female; Glossopharyngeal Nerve; Humans; Male; Middle Aged; Neuralgia; Phenytoin; Syncope | 1977 |
Pediatric psychopharmacology. A review with special reference to deanol.
Topics: Adolescent; Adult; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; Chlorpromazine; Deanol; Epilepsy; Ethanolamines; Heart Rate; Humans; Learning; Methylphenidate; Pemoline; Phenytoin; Rats; Syndrome; Thioridazine | 1977 |
[The psycho-motor epilepsy (author's transl)].
Topics: Adolescent; Adult; Brain Injuries; Carbamazepine; Child; Diagnosis, Differential; Diseases in Twins; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Limbic System; Phenytoin; Primidone; Prognosis; Syncope | 1978 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
The effect of anti-convulsant drugs on cognitive abilities.
Topics: Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Psychological Tests | 1979 |
[Physiopathology of trigeminal neuralgia].
Topics: Carbamazepine; Humans; Phenytoin; Trigeminal Ganglion; Trigeminal Nerve; Trigeminal Neuralgia | 1979 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
Drugs used in the management of trigeminal neuralgia.
Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia; Valproic Acid | 1992 |
Metabolism of antiepileptic medication: newborn to elderly.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Half-Life; Humans; Infant, Newborn; Male; Middle Aged; Phenytoin; Valproic Acid | 1992 |
Rational use of antiepileptic drug levels.
Topics: Carbamazepine; Half-Life; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1992 |
[The current treatment of trigeminal neuralgia. Experience in 162 thermorhizotomies].
Topics: Aged; Baclofen; Carbamazepine; Diagnosis, Differential; Electrocoagulation; Facial Neuralgia; Humans; Phenytoin; Tic Disorders; Trigeminal Ganglion; Trigeminal Neuralgia | 1992 |
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monitoring; Epilepsy; Ethosuximide; Humans; Leukopenia; Phenytoin; Thrombocytopenia; Valproic Acid | 1991 |
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.
Topics: Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Humans; Mephenytoin; Mephobarbital; Oxcarbazepine; Phenytoin; Primidone; Valproic Acid | 1991 |
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Epilepsy; Humans; Pentobarbital; Phenobarbital; Phenytoin; Postoperative Complications; Seizures; Substance Withdrawal Syndrome | 1991 |
Neurobehavioral effects of phenytoin, carbamazepine, and valproic acid: implications for use in traumatic brain injury.
Topics: Barbiturates; Brain Injuries; Carbamazepine; Cognition; Contraindications; Humans; Phenytoin; Valproic Acid | 1991 |
The newer antiepileptic drugs: carbamazepine and valproic acid.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Humans; Infant; Infant, Newborn; Phenytoin; Valproic Acid | 1991 |
Cognitive effects of antiepileptic drugs.
Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Cognition; Drug Tolerance; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Aspects of antiepileptic drug therapy in children].
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Combinations; Humans; Phenytoin; Valproic Acid | 1990 |
Clinical pharmacology of drugs used to treat head and face pain.
Topics: Baclofen; Carbamazepine; Facial Pain; Humans; Migraine Disorders; Phenytoin; Trigeminal Neuralgia | 1990 |
Generic substitutions for antiepileptic drugs.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Costs and Cost Analysis; Humans; Informed Consent; Liability, Legal; Pharmacopoeias as Topic; Phenytoin; Therapeutic Equivalency; United States; United States Food and Drug Administration | 1990 |
Antiepileptic drugs, cognitive function, and behavior in children: evidence from recent studies.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin; Psychological Tests; Research Design; Valproic Acid | 1990 |
Adverse effects of antiepileptic drugs in children. The relevance of drug interaction.
Topics: Anticonvulsants; Carbamazepine; Child; Drug Interactions; Humans; Phenytoin; Valproic Acid | 1989 |
Poisoning by anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; Female; Fetus; Haloperidol; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione; Valproic Acid | 1989 |
Medical treatment and pharmacology of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Half-Life; Humans; Phenytoin | 1989 |
Efficacy and adverse effects of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy | 1989 |
The pharmacology of trigeminal neuralgia.
Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia; Trigeminal Nuclei | 1989 |
Adverse neuropsychiatric effects of anticonvulsant drugs.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biogenic Amines; Carbamazepine; Cerebellar Ataxia; Dystonia; Ethosuximide; Folic Acid Deficiency; Hormones; Humans; Mental Disorders; Nervous System Diseases; Peripheral Nervous System Diseases; Phenytoin; Rats; Tremor; Valproic Acid | 1985 |
Anticonvulsant drugs: mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Biomechanical Phenomena; Carbamazepine; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Phenytoin; Primidone; Succinimides; Synapses; Synaptic Transmission; Valproic Acid | 1986 |
[Drugs and the thyroid gland].
Topics: Adrenergic beta-Antagonists; Amiodarone; Carbamazepine; Danazol; Drug-Related Side Effects and Adverse Reactions; Furosemide; Humans; Lithium; Phenylacetates; Phenytoin; Thyroid Gland | 1987 |
Use of phenytoin and carbamazepine in treatment of epilepsy.
Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognition Disorders; Drug Eruptions; Drug Interactions; Epilepsy; Gingival Hyperplasia; Half-Life; Humans; Inappropriate ADH Syndrome; Phenytoin; Tremor | 1986 |
A molecular approach to the calcium signal in brain: relationship to synaptic modulation and seizure discharge.
Topics: Animals; Anticonvulsants; Benzodiazepines; Binding, Competitive; Brain; Calcium; Calmodulin; Carbamazepine; Diazepam; Humans; Phenytoin; Phosphorylation; Protein Kinases; Receptors, Drug; Receptors, GABA-A; Seizures; Stimulation, Chemical; Synapses; Synaptic Membranes; Synaptic Transmission; Synaptic Vesicles | 1986 |
Medical treatment of the major neuralgias.
Topics: Baclofen; Carbamazepine; Chlorphenesin; Combined Modality Therapy; Facial Neuralgia; Glossopharyngeal Nerve; Humans; Phenytoin; Trigeminal Neuralgia | 1988 |
Therapeutic drug monitoring in childhood.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid | 1986 |
Status epilepticus.
Topics: Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Infant, Newborn; Lidocaine; Paraldehyde; Phenytoin; Status Epilepticus; Terminology as Topic; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Mechanisms of anticonvulsant drug action. I. Drugs primarily used for generalized tonic-clonic and partial epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Kinetics; Phenobarbital; Phenytoin | 1987 |
Hepatic considerations in the use of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Liver; Phenytoin; Risk Factors; Time Factors; Valproic Acid | 1987 |
Carbamazepine efficacy in adults with partial and generalized tonic-clonic seizures.
Topics: Adult; Carbamazepine; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Phenytoin | 1987 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
[Therapy of brain-related minor seizures].
Topics: Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy, Absence; Humans; Phenytoin; Seizures; Valproic Acid | 1988 |
Intraparenchymal cerebral cysticercosis in children: diagnosis and treatment.
Topics: Acute Disease; Adolescent; Adult; Animals; Black People; Brain Diseases; Calcinosis; Carbamazepine; Child; Child, Preschool; Cysticercosis; Diagnosis, Differential; Female; Follow-Up Studies; Hispanic or Latino; Humans; Infant; Phenytoin; Praziquantel; Prognosis; Recurrence; Retrospective Studies; Seizures; Tomography, X-Ray Computed | 1988 |
[Therapy in alcoholic delirium].
Topics: Alcohol Withdrawal Delirium; Carbamazepine; Chlormethiazole; Diazepam; Haloperidol; Humans; Phenytoin; Psychoses, Alcoholic | 1987 |
Anticonvulsant drugs and cognitive function: a review of the literature.
Topics: Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin | 1987 |
[Neurotraumatology and post-traumatic epilepsy. Prevention, treatment and long-term follow-up. Barbexaclone + phenobarbital (maliasin) versus diphenylhydantoin, phenobarbital, primidone, carbamazepine].
Topics: Adolescent; Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Current concepts. Seizure disorders and pregnancy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Epilepsy; Female; Fetal Blood; Hemorrhage; Humans; Infant, Newborn; Monitoring, Physiologic; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione | 1985 |
Isoniazid interactions.
Topics: Animals; Antacids; Anticoagulants; Biological Availability; Carbamazepine; Drug Interactions; Food; Humans; Intestinal Absorption; Isoniazid; Phenytoin | 1985 |
[Trigeminal neuralgia. Treatment].
Topics: Baclofen; Carbamazepine; Glycerol; Humans; Nerve Block; Nerve Compression Syndromes; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1985 |
Effects of different classes of antiepileptic drugs on brain-stem pathways.
Topics: Animals; Anticonvulsants; Baclofen; Brain Stem; Carbamazepine; Disease Models, Animal; Electroshock; Ethosuximide; Phenytoin; Reticular Formation; Valproic Acid | 1985 |
Determination of antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Chromatography, Liquid; Clonazepam; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Humans; Mephenytoin; Monitoring, Physiologic; Phenytoin; Primidone; Succinimides; Valproic Acid | 1985 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Plasma levels of anticonvulsants.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Barbiturates; Blood Proteins; Carbamazepine; Child; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Liver; Phenytoin; Protein Binding; Spectrophotometry; Thiazines; Trimethadione | 1973 |
Comparative mechanisms of action of antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil | 1974 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione | 1974 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Treatment of trigeminal neuralgia.
Topics: Anorexia Nervosa; Blood Cell Count; Carbamazepine; Female; Humans; Male; Middle Aged; Nausea; Phenytoin; Trigeminal Neuralgia; Vertigo; Vomiting | 1972 |
Epilepsy.
Topics: Animals; Brain; Carbamazepine; Diet Therapy; Epilepsy; Humans; Phenobarbital; Phenytoin | 1972 |
Epilepsy in the adolescent.
Topics: Acetazolamide; Adolescent; Age Factors; Alcoholic Intoxication; Amphetamine; Anticonvulsants; Attitude to Health; Carbamazepine; Cerebral Cortex; Contraceptives, Oral; Drug Interactions; Electroencephalography; Epilepsy; Female; Humans; Lysergic Acid Diethylamide; Male; Phenobarbital; Phenytoin; Psychology; Puberty; Substance-Related Disorders | 1974 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
Psychopharmacological aspects of antiepileptic treatment.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenytoin; Psychological Tests; Psychometrics; Psychotropic Drugs; Research Design; Sampling Studies; Thiazines; Valproic Acid | 1980 |
[Advance and clinic of antiepileptic drugs (author's transl)].
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Epilepsy; Humans; Ion Channels; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1981 |
Lithium and drug interactions.
Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Carbamazepine; Diuretics; Drug Interactions; Humans; Iodides; Lithium; Methyldopa; Neuromuscular Blocking Agents; Phenytoin; Tetracyclines | 1982 |
The effects of drugs on the distribution and metabolism of thyroid hormones.
Topics: Animals; Antithyroid Agents; Carbamazepine; Carcinogens; Female; Heparin; Hormones; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Propranolol; Salicylates; Thyroid Hormones; Thyroxine-Binding Proteins | 1981 |
[Anticonvulsants and their side effects. II. Side effects].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Primidone; Succinimides; Valproic Acid | 1980 |
Reassessment of the concept of a therapeutic range of anticonvulsant plasma levels.
Topics: Anticonvulsants; Binding Sites; Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Genetic Variation; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Time Factors | 1983 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
Mental effects of antiepileptic medication: a review.
Topics: Adolescent; Adult; Anticonvulsants; Attention; Barbiturates; Brain Chemistry; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Mental Processes; Phenytoin; Psychomotor Performance; Psychoses, Substance-Induced; Serotonin; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Clinical pharmacokinetics of sodium valproate, carbamazepine and phenytoin. Level-dose ration and interactions.
Topics: Carbamazepine; Drug Interactions; Epilepsy; Humans; Intestinal Absorption; Kinetics; Phenytoin; Valproic Acid | 1984 |
Pharmacokinetic interactions of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Drug Interactions; Humans; In Vitro Techniques; Intestinal Absorption; Kidney; Kinetics; Phenytoin; Protein Binding; Rats; Succinimides; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Anticonvulsant drugs in alcohol withdrawal: use of phenytoin, primidone, carbamazepine, valproic acid, and the sedative anticonvulsants.
Topics: Alcoholism; Anticonvulsants; Carbamazepine; Humans; Hypnotics and Sedatives; Phenytoin; Primidone; Status Epilepticus; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[The post-traumatic epilepsy (author's transl)].
Topics: Brain Concussion; Brain Injuries; Brain Neoplasms; Carbamazepine; Diagnostic Errors; Electroencephalography; Ependymoma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin; Primidone; Skull | 1981 |
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Phenobarbital; Phenytoin; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Protein Binding; Status Epilepticus; Valproic Acid | 1982 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
[Enzyme induction in the liver changes drug activity].
Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors | 1980 |
[An overview of trigeminal neuralgia].
Topics: Adult; Age Factors; Aged; Carbamazepine; Electrocoagulation; Humans; Middle Aged; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1980 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline | 1981 |
[Side effects of phenytoin and carbamazepine on cognitive functioning].
Topics: Anticonvulsants; Carbamazepine; Cognition; Humans; Mental Processes; Phenytoin | 1994 |
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 1995 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
Phenytoin and carbamazepine: differential effects on cognitive function.
Topics: Carbamazepine; Clinical Trials as Topic; Cognition; Drug Therapy, Combination; Epilepsy; Humans; Neuropsychological Tests; Phenytoin; Risk Factors | 1995 |
The consulting psychiatrist and the polydipsia-hyponatremia syndrome in schizophrenia.
Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Carbamazepine; Cognition Disorders; Demeclocycline; Drinking Behavior; Electroconvulsive Therapy; Humans; Hyponatremia; Lithium; Mood Disorders; Naloxone; Phenytoin; Polyuria; Propranolol; Psychiatry; Psychotherapy; Schizophrenia; Sodium Chloride; Syndrome; Water Intoxication; Workforce | 1994 |
The medical and surgical management of trigeminal neuralgia.
Topics: Baclofen; Carbamazepine; Combined Modality Therapy; Facial Nerve; Humans; Phenytoin; Postoperative Complications; Risk Assessment; Trigeminal Neuralgia | 1995 |
Standard approach to antiepileptic drug treatment in the United Kingdom.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Prognosis; United Kingdom; Valproic Acid | 1994 |
Pharmacologic intervention and treatment of childhood seizure disorders: relative efficacy and safety of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; Mice; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid | 1994 |
[Drug-induced pseudolymphoma with predominantly cutaneous manifestation].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Female; France; Humans; Lymphoma; Male; Middle Aged; Phenytoin; Product Surveillance, Postmarketing; Skin Neoplasms | 1993 |
Treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1993 |
Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenytoin; Thiazines; Triazines; Vigabatrin | 1995 |
Drug interaction profile of topiramate.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Male; Phenytoin; Topiramate; Treatment Outcome; Valproic Acid | 1996 |
Antiepileptic drug mechanisms of action.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Calcium Channels; Carbamazepine; Central Nervous System; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Phenytoin; Rats; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Sodium Channels; Triazines; Trimethadione; Valproic Acid; Vigabatrin | 1995 |
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Nervous System Diseases; Oxcarbazepine; Phenobarbital; Phenytoin; Sleep Stages; Vigabatrin | 1995 |
Cytochrome P450 isozymes and antiepileptic drug interactions.
Topics: Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Mixed Function Oxygenases; Oxidoreductases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenytoin | 1995 |
Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin | 1996 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
Antiepileptic drugs--current use.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1996 |
[The diagnosis and treatment of partial epilepsy in childhood and adolescence].
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Frontal Lobe; Epilepsy, Temporal Lobe; Humans; Infant; Phenytoin; Sleep, REM; Valproic Acid | 1996 |
[Antiepileptic drugs: mechanism of action].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenytoin; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Triazines; Vigabatrin | 1996 |
Established antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Phenytoin; Succinimides; Valproic Acid | 1996 |
Pharmacologic and dietary therapies in epilepsy: conventional treatments and recent advances.
Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketone Bodies; Lamotrigine; Phenylcarbamates; Phenytoin; Propylene Glycols; Triazines; Valproic Acid; Vigabatrin | 1997 |
Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation.
Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Epilepsy; Felbamate; Humans; In Vitro Techniques; Isoenzymes; Neuroprotective Agents; Phenylcarbamates; Phenytoin; Propylene Glycols; Valproic Acid | 1997 |
Anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Syndrome | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Features and management of poisoning with modern drugs used to treat epilepsy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Incidence; Male; Phenobarbital; Phenytoin; Primidone; Syndrome | 1998 |
Mechanisms of idiosyncratic hypersensitivity reactions to antiepileptic drugs.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme System; Drug Hypersensitivity; Epilepsy; Genotype; Humans; Liver; Models, Immunological; Phenytoin; Polymorphism, Genetic | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
Trigeminal neuralgia.
Topics: Anticonvulsants; Baclofen; Carbamazepine; Diagnosis, Differential; Humans; Incidence; Muscle Relaxants, Central; Phenytoin; Trigeminal Neuralgia | 1997 |
[Neurotoxicity of anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone; Valproic Acid | 1999 |
Ticlopidine and clopidogrel.
Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bone Marrow Diseases; Carbamazepine; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug Interactions; Hemorrhage; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Phenytoin; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Safety; Stents; Theophylline; Thrombolytic Therapy; Ticlopidine | 1999 |
[Ion-channel related muscular diseases].
Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Carbamazepine; Humans; Hypokalemic Periodic Paralysis; Ion Channels; Mexiletine; Mutation; Myotonia; Paralysis, Hyperkalemic Periodic; Phenytoin; Potassium Chloride | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Oxcarbazepine.
Topics: Adult; Animals; Anticonvulsants; Biological Availability; Biotransformation; Carbamazepine; Controlled Clinical Trials as Topic; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Epilepsy; Humans; Oxcarbazepine; Phenytoin; Treatment Outcome | 1999 |
Is generic prescribing acceptable in epilepsy?
Topics: Anticonvulsants; Area Under Curve; Biological Availability; Carbamazepine; Chemistry, Pharmaceutical; Drugs, Generic; Epilepsy; Humans; Phenytoin; Therapeutic Equivalency; Valproic Acid | 2000 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
Trigeminal neuralgia--an update.
Topics: Acupuncture Analgesia; Anticonvulsants; Baclofen; Carbamazepine; Facial Pain; GABA Agonists; Homeopathy; Humans; Neurosurgical Procedures; Phenytoin; Trigeminal Neuralgia | 2000 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid | 2001 |
Treatment of epilepsy in 3 specialized populations.
Topics: Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Female; Humans; Outcome Assessment, Health Care; Phenytoin; Polypharmacy; Pregnancy; Teratogens; Valproic Acid | 2001 |
Trigeminal neuralgia: current concepts and management.
Topics: Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Humans; Phenytoin; Pimozide; Radiosurgery; Trigeminal Ganglion; Trigeminal Neuralgia | 2001 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Inactivation, Metabolic; Lamotrigine; Neuralgia; Phenytoin; Substance Withdrawal Syndrome; Triazines; Valproic Acid | 1998 |
Carbamazepine versus phenytoin monotherapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Randomized Controlled Trials as Topic | 2002 |
Practice parameter: antiepileptic drug prophylaxis in severe traumatic brain injury: report of the Quality Standards Subcommittee of the American Academy of Neurology.
Topics: Acute Disease; Adult; Animals; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Post-Traumatic; Humans; Models, Animal; Phenytoin; Prospective Studies; Risk; Risk Assessment; Time Factors; Treatment Outcome | 2003 |
New antiepileptic drug therapies.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 2002 |
Neuropathic cranial pain.
Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Fructose; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Lamotrigine; Nervous System Diseases; Phenytoin; Topiramate; Triazines | 2003 |
Phenytoin and carbamazepine cross reactivity: report of a case and review of literature.
Topics: Anticonvulsants; Carbamazepine; Child; Drug Eruptions; Drug Interactions; Humans; Male; Oral Ulcer; Oxcarbazepine; Phenytoin; Seizures | 2003 |
[Clinical guidelines for treatment of epilepsy in children].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Cosyntropin; Electroencephalography; Epilepsy; Frontal Lobe; Humans; Isoxazoles; Life Style; Magnetic Resonance Imaging; Phenytoin; Practice Guidelines as Topic; Temporal Lobe; Valproic Acid; Zonisamide | 2004 |
Trigeminal neuralgia and glossopharyngeal neuralgia.
Topics: Analgesics, Non-Narcotic; Anticonvulsants; Baclofen; Carbamazepine; GABA Agonists; Glossopharyngeal Nerve Diseases; Humans; Phenytoin; Trigeminal Neuralgia | 2004 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2004 |
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats; Risk Factors; Valproic Acid | 2005 |
Management issues of neuropathic trigeminal pain from a medical perspective.
Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2004 |
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.
Topics: Animals; Biological Transport; Carbamazepine; Embryonic Development; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Placenta; Pregnancy; Rabbits; Rats; Salicylic Acid; Species Specificity; Teratogens; Toxicity Tests; Tretinoin; Valproic Acid; Yolk Sac | 2004 |
Oxcarbazepine versus phenytoin monotherapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Oxcarbazepine; Phenytoin; Randomized Controlled Trials as Topic; Remission Induction | 2006 |
[Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].
Topics: Androgens; Anticonvulsants; Bromocriptine; Carbamazepine; Cognition; Enzyme Induction; Epilepsy; Gonadal Steroid Hormones; Humans; Lamotrigine; Liver; Male; Oxcarbazepine; Phenytoin; Sexual Dysfunctions, Psychological; Testosterone; Triazines; Valproic Acid | 2006 |
[Anticonvulsants treatment of psychiatric disorder in elderly patients].
Topics: Aged; Anticonvulsants; Anxiety Disorders; Bipolar Disorder; Carbamazepine; Epilepsy; Humans; Mental Disorders; Mood Disorders; Phenytoin; Psychotic Disorders; Valproic Acid | 2006 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
Pharmacokinetics of antiepileptic drugs in elderly nursing home residents.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Nursing Homes; Phenobarbital; Phenytoin; Valproic Acid | 2007 |
[Anticonvulsants in the treatment of bipolar disorder].
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2007 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
Antiepileptic drugs as human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2008 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Antiepileptic drugs and thyroid function.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenytoin; Thyroid Gland; Thyroid Hormones; Valproic Acid | 2008 |
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; Chemical and Drug Induced Liver Injury; Cyclohexanecarboxylic Acids; Diagnostic Errors; Drug Eruptions; Drug Therapy, Combination; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Gabapentin; gamma-Aminobutyric Acid; Ganglioneuroma; Humans; Lymphatic Diseases; Parahippocampal Gyrus; Phenytoin; Radiosurgery | 2009 |
New antiepileptic drugs: molecular targets.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Carbamazepine; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Monitoring; Electroshock; Epilepsy; Ethosuximide; gamma-Aminobutyric Acid; Humans; Molecular Structure; Neurotransmitter Transport Proteins; Phenytoin; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Synaptic Transmission; Treatment Outcome; Valproic Acid | 2009 |
[Antiepileptic drugs in North America].
Topics: Anticonvulsants; Carbamazepine; Drug Approval; Fructose; Humans; Japan; Lamotrigine; Levetiracetam; Lorazepam; North America; Phenytoin; Piracetam; Topiramate; Triazines | 2010 |
Question 2 Should phenytoin and carbamazepine be avoided in Asian populations with the HLA-B*1502 positive genetic variant?
Topics: Anticonvulsants; Asian People; Carbamazepine; Child; Contraindications; Drug Eruptions; Epilepsy; Evidence-Based Medicine; HLA-B Antigens; HLA-B15 Antigen; Humans; Phenytoin | 2011 |
Epilepsy (generalised).
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remission Induction; Valproic Acid | 2010 |
Side effects of phenobarbital in epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Cohort Studies; Cross-Over Studies; Data Collection; Data Interpretation, Statistical; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic; Research; Research Design; Treatment Outcome; Valproic Acid | 2011 |
The effects of antiepileptic drugs on oral health.
Topics: Alveolar Bone Loss; Anticonvulsants; Carbamazepine; Epilepsy; Gingival Hyperplasia; Humans; Oral Health; Phenobarbital; Phenytoin | 2011 |
Epilepsy (generalised).
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epilepsy, Generalized; Humans; Incidence; Phenytoin; Remission Induction; Valproic Acid | 2012 |
Efficacy and safety of innovator versus generic drugs in patients with epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drugs, Generic; Endpoint Determination; Epilepsy; Hospitalization; Humans; Length of Stay; Meta-Analysis as Topic; Phenytoin; Randomized Controlled Trials as Topic; Treatment Outcome; Valproic Acid | 2012 |
Impact of particular antiepileptic drugs on the survival of patients with glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Carbamazepine; Cohort Studies; Female; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Phenytoin; Survival Rate; Treatment Outcome; Valproic Acid; Young Adult | 2013 |
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Induction Chemotherapy; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Recurrence; Seizures; Time Factors; Valproic Acid | 2013 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2013 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
Oxcarbazepine versus phenytoin monotherapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Induction Chemotherapy; Oxcarbazepine; Phenytoin; Randomized Controlled Trials as Topic | 2013 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
Antiepileptic drugs: Energy-consuming processes governing drug disposition.
Topics: Anticonvulsants; Biological Transport; Carbamazepine; Cardiac Output; Energy Metabolism; Humans; Intestinal Absorption; Kidney; Liver; Membrane Transport Modulators; Phenytoin; Valproic Acid | 2014 |
Clobazam monotherapy for partial-onset or generalized-onset seizures.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Clobazam; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures | 2014 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2015 |
[ZONISAMIDE: FIRST CHOICE AMONG THE FIRST-LINE ANTIEPILEPTIC DRUGS IN FOCAL EPILEPSY].
Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Approval; Drug Prescriptions; Electroencephalography; Encephalitis; Epilepsies, Partial; Humans; Hungary; Isoxazoles; Levetiracetam; Magnetic Resonance Imaging; Medication Adherence; Obesity; Phenytoin; Piracetam; Risk Assessment; Risk Factors; Seizures; Stroke; Weight Loss; Young Adult; Zonisamide | 2015 |
Pharmacological treatments for preventing epilepsy following traumatic head injury.
Topics: Adult; Anticonvulsants; Carbamazepine; Cause of Death; Child; Craniocerebral Trauma; Epilepsy; Humans; Levetiracetam; Magnesium Sulfate; Neuroprotective Agents; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Valproic Acid | 2015 |
Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Humans; Induction Chemotherapy; Phenytoin; Randomized Controlled Trials as Topic; Withholding Treatment | 2015 |
Antiepileptic drugs for seizure control in people with neurocysticercosis.
Topics: Adolescent; Adult; Anticonvulsants; Brain Diseases; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Middle Aged; Neurocysticercosis; Phenytoin; Randomized Controlled Trials as Topic; Seizures | 2015 |
Antiepileptic Drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Seizures; Triazines | 2016 |
Pain management strategies for neuropathic pain in Fabry disease--a systematic review.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fabry Disease; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuralgia; Phenytoin | 2016 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Humans; Induction Chemotherapy; Phenytoin; Randomized Controlled Trials as Topic; Time Factors; Withholding Treatment | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Essential Oils as an Alternative to Pyrethroids' Resistance against Anopheles Species Complex Giles (Diptera: Culicidae).
Topics: Animals; Anopheles; Caco-2 Cells; Carbamazepine; Diptera; Hep G2 Cells; Humans; Lamotrigine; Levetiracetam; Oils, Volatile; Phenytoin; Piracetam; Pyrethrins; Triazines; Valproic Acid | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Genetic variation in
Topics: Anticonvulsants; Apolipoproteins; Asian People; Carbamazepine; Case-Control Studies; Complement Factor H; Drug Eruptions; Epilepsy; Genetic Variation; Genome-Wide Association Study; HLA-A Antigens; Humans; Linkage Disequilibrium; Mutation, Missense; Pharmacogenomic Variants; Phenytoin; Retrospective Studies; White People | 2018 |
Seizures and Choice of Antiepileptic Drugs Following Subarachnoid Hemorrhage: A Review.
Topics: Anticonvulsants; Carbamazepine; Humans; Incidence; Levetiracetam; Phenytoin; Seizures; Subarachnoid Hemorrhage | 2017 |
Role of cytochrome P450-mediated metabolism and involvement of reactive metabolite formations on antiepileptic drug-induced liver injuries.
Topics: Animals; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Glutathione; Humans; Models, Animal; Phenytoin | 2018 |
Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug and Narcotic Control; Drug-Related Side Effects and Adverse Reactions; Humans; Lamotrigine; Levetiracetam; Nitriles; Phenytoin; Pyridones; Seizures; Topiramate; Treatment Outcome | 2018 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2018 |
Clobazam monotherapy for focal or generalized seizures.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Clobazam; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenytoin; Randomized Controlled Trials as Topic; Seizures | 2018 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review.
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Phenytoin; Randomized Controlled Trials as Topic; Remission Induction; Seizures; Treatment Failure; Treatment Outcome | 2019 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2020 |
Anticonvulsant hypersensitivity syndrome: clinic case and literature review.
Topics: Adult; Anticonvulsants; Argentina; Carbamazepine; Drug Hypersensitivity Syndrome; Female; Humans; Phenytoin | 2020 |
Duration and choices of prophylactic anticonvulsants in subarachnoid hemorrhage: a systematic review and meta-analysis.
Topics: Anticonvulsants; Bayes Theorem; Carbamazepine; Humans; Phenytoin; Subarachnoid Hemorrhage | 2021 |
Population Pharmacokinetics of Levetiracetam: A Systematic Review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Female; Humans; Infant, Newborn; Levetiracetam; Phenytoin; Piracetam; Pregnancy | 2021 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Efficacy and Safety of Phenobarbitone as First-Line Treatment for Neonatal Seizure: A Systematic Review and Meta-Analysis.
Topics: Anticonvulsants; Carbamazepine; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Seizures | 2021 |
A review of pharmacokinetic drug interactions between antimicrobial and antiseizure medications in children.
Topics: Anti-Bacterial Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Drug Interactions; Humans; Pharmaceutical Preparations; Phenytoin; Valproic Acid; Voriconazole | 2021 |
Comparative efficacy of prophylactic anticonvulsant drugs following traumatic brain injury: A systematic review and network meta-analysis of randomized controlled trials.
Topics: Anticonvulsants; Brain Injuries, Traumatic; Carbamazepine; Child; Humans; Levetiracetam; Network Meta-Analysis; Phenytoin; Piracetam; Randomized Controlled Trials as Topic; Seizures | 2022 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches.
Topics: Anticonvulsants; Carbamazepine; Dementia; Epilepsy; Felbamate; Gabapentin; Humans; Inflammasomes; Lamotrigine; Mitophagy; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxcarbazepine; Parkinson Disease; Phenytoin; Seizures; Topiramate; Triazines; Ubiquitin-Protein Ligases; Valproic Acid | 2022 |
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
152 trial(s) available for phenytoin and carbamazepine
| Article | Year |
|---|---|
Carbamazepine vs phenytoin. A controlled clinical trial in focal motor and generalized epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 1979 |
[Carbamazepine (Tegretol) or phenytoin in the treatment of focal motor epilepsy or generalized epilepsy? A controlled clinical trial].
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenytoin | 1979 |
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Female; Humans; Hydrocephalus; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Spasms, Infantile; Valerates; Valproic Acid | 1977 |
Psychotropic effects of carbamazepine in epilepsy: a double-blind comparison with phenytoin.
Topics: Adult; Attention; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Emotions; Epilepsy; Female; Humans; Male; Mental Processes; MMPI; Phenytoin | 1977 |
Carbamazepine and the electroencephalogram of epileptics: a double blind study in comparison to phenytoin.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Electroencephalography; Epilepsy; Humans; Hyperventilation; Phenytoin | 1978 |
Sodium valproate, serum level and clinical effect in epilepsy: a controlled study.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dimethadione; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Carbamazepine--a double-blind comparison with phenytoin.
Topics: Adult; Ataxia; Carbamazepine; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Partial; Hematocrit; Humans; Leukocyte Count; Phenytoin | 1977 |
One drug for epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies | 1978 |
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone | 1979 |
A comparative controlled study between carbamazepine and diphenylhydantoin in psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Patient Dropouts; Phenytoin | 1976 |
Carbamazepine in difficult to control epileptic out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Leukocyte Count; Middle Aged; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Placebos | 1975 |
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Middle Aged; Phenobarbital; Phenytoin | 1975 |
[Carbamazepine versus phenytoin in psychomotor epilepsy. A double-blind study of antiepileptic effect and side-effects].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenytoin | 1975 |
Carbamazepine (Tegretol) as an anticonvulsant. A controlled double-blind comparison with diphenylhydantoin (Dilantin).
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Epilepsy; Half-Life; Humans; Phenytoin; Pilot Projects | 1975 |
A double blind study of carbamazepine and diphenylhydantoin in temporal lobe epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Epilepsy, Temporal Lobe; Humans; Middle Aged; Phenytoin | 1975 |
The efficacy of carbamazepine combinations in epilepsy.
Topics: Adult; Biological Availability; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1975 |
Fluctuation of serum phenytoin concentrations during autologous bone marrow transplant for primary central nervous system tumors.
Topics: Adult; Anticonvulsants; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carbamazepine; Female; Glioblastoma; Humans; Lymphoma; Male; Melanoma; Middle Aged; Phenytoin; Transplantation, Autologous | 1992 |
Cognitive effects of oxcarbazepine and phenytoin monotherapy in newly diagnosed epilepsy: one year follow-up.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Cognition; Double-Blind Method; Epilepsy; Female; Humans; Male; Memory; Oxcarbazepine; Phenytoin; Psychomotor Performance | 1992 |
Do prophylactic anticonvulsant drugs alter the pattern of seizures after craniotomy?
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Brain Diseases; Carbamazepine; Craniotomy; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Postoperative Complications; Premedication; Prospective Studies | 1992 |
Effect of single- and multiple-dose carbamazepine on the pharmacokinetics of diphenylhydantoin.
Topics: Adult; Carbamazepine; Drug Administration Schedule; Humans; Male; Phenytoin | 1992 |
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1992 |
Neuroleptics in painful thiamine deficiency neuropathy.
Topics: Aged; Carbamazepine; Electromyography; Humans; Male; Middle Aged; Neural Conduction; Pain; Peripheral Nervous System Diseases; Phenytoin; Thiamine Deficiency | 1991 |
Cognitive impairment in new cases of epilepsy randomly assigned to carbamazepine, phenytoin and sodium valproate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition; Epilepsy; Humans; Intelligence Tests; Phenytoin; Random Allocation; Valproic Acid | 1991 |
Comparative cognitive effects of carbamazepine and phenytoin in healthy adults.
Topics: Adult; Carbamazepine; Cognition; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin | 1991 |
Felbamate for partial seizures: results of a controlled clinical trial.
Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols | 1991 |
Post-operative epilepsy and the efficacy of anticonvulsant therapy.
Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsies, Partial; Follow-Up Studies; Glioma; Humans; Intracranial Aneurysm; Intracranial Arteriovenous Malformations; Meningeal Neoplasms; Meningioma; Phenytoin; Postoperative Complications; Prospective Studies; Retrospective Studies; Risk Factors; Subarachnoid Hemorrhage | 1990 |
Discontinuation of antiepileptic drugs in children who have outgrown epilepsy: effects on cognitive function.
Topics: Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Epilepsy; Ethosuximide; Humans; Memory, Short-Term; Phenytoin; Psychomotor Performance; Reaction Time; Valproic Acid | 1990 |
[Clinical and experimental control of optimal therapy in epilepsy].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Neurocognitive Disorders; Neuropsychological Tests; Phenytoin; Primidone; Substance-Related Disorders; Valproic Acid | 1990 |
Comparative cognitive effects of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Random Allocation; Statistics as Topic | 1990 |
Compliant populations: variability in serum concentrations.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Felbamate; Female; gamma-Aminobutyric Acid; Humans; Male; Patient Compliance; Phenylcarbamates; Phenytoin; Propylene Glycols; Random Allocation | 1988 |
Serum levels of sodium valproate, phenytoin and carbamazepine and seizure control in epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1986 |
Withdrawal of anticonvulsant drugs in patients free of seizures for two years. A prospective study.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Phenytoin; Prognosis; Prospective Studies; Random Allocation; Recurrence; Substance Withdrawal Syndrome; Time Factors; Valproic Acid | 1988 |
Valproic acid in Isaacs-Mertens syndrome.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Electromyography; Humans; Middle Aged; Muscles; Neuromuscular Diseases; Phenytoin; Sural Nerve; Syndrome; Valproic Acid | 1987 |
Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Substance Withdrawal Syndrome; Valproic Acid | 1988 |
Aspects of compliance: taking drugs and keeping clinic appointments.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Outpatient Clinics, Hospital; Patient Compliance; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1988 |
A controlled study of progabide in partial seizures: methodology and results.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Seizures | 1987 |
Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1987 |
Effect of progabide on serum phenytoin and carbamazepine concentrations.
Topics: Adult; Carbamazepine; Convulsants; Double-Blind Method; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Male; Phenytoin; Random Allocation; Seizures | 1987 |
Progabide for refractory partial epilepsy: a controlled add-on trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Random Allocation | 1986 |
Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Asthma; Biological Availability; Carbamazepine; Child; Half-Life; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Research Design | 1987 |
The interaction of denzimol (a new anticonvulsant) with carbamazepine and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Epilepsies, Partial; Humans; Imidazoles; Phenytoin | 1985 |
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Leukocyte Count; Lupus Vulgaris; Lymphoma; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced | 1985 |
[Efficient serum concentrations after single doses of antiepileptic drugs: concept of loading-dose].
Topics: Absorption; Administration, Oral; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Kinetics; Male; Phenytoin; Valproic Acid | 1985 |
A prospective study between carbamazepine, phenytoin and sodium valproate as monotherapy in previously untreated and recently diagnosed patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Evoked Potentials; Female; Humans; Kinetics; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1985 |
Carbamazepine for epilepsy. A controlled prospective evaluation.
Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Leukopenia; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Prospective Studies; Psychiatric Status Rating Scales | 1974 |
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.
Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials as Topic; Computers; Drug Evaluation; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Telemetry | 1974 |
Painful tonic seizure in multiple sclerosis.
Topics: Adult; Animals; Brain Stem; Carbamazepine; Cerebellum; Cerebral Cortex; Clinical Trials as Topic; Demyelinating Diseases; Evaluation Studies as Topic; Female; Humans; Japan; Male; Middle Aged; Multiple Sclerosis; Optic Lobe, Nonmammalian; Pain; Phenytoin; Seizures; Spinal Cord | 1974 |
[Short report on the effect of the anticonvulsant Ro 5-4023 (clonazepam) in different forms of epilepsy].
Topics: Adolescent; Anticonvulsants; Barbiturates; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Chlorobenzenes; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Hormones; Humans; Infant; Male; Nitrazepam; Nitro Compounds; Oxyphenbutazone; Phenytoin; Succinimides; Valerates | 1973 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Fatigue; Female; Humans; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1973 |
Interaction between doxycycline and some antiepileptic drugs.
Topics: Adult; Aged; Carbamazepine; Clinical Trials as Topic; Doxycycline; Drug Interactions; Drug Therapy, Combination; Female; Half-Life; Humans; Male; Middle Aged; Phenytoin | 1974 |
A long-term low-dosage study of carbamazepine in trigeminal neuralgia.
Topics: Carbamazepine; Clinical Trials as Topic; Dibenzazepines; Drug Synergism; Humans; Middle Aged; Phenytoin; Placebos; Trigeminal Neuralgia | 1969 |
Clinical trials of tegretol in trigeminal neuralgia.
Topics: Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dibenzazepines; Drug Synergism; Facial Neuralgia; Female; Humans; Male; Mephenesin; Middle Aged; Phenytoin; Placebos; Trigeminal Neuralgia | 1969 |
Painful tonic seizure in multiple sclerosis treatment with diphenylhydantoin and carbamazepine.
Topics: Adult; Carbamazepine; Dibenzazepines; Electrocardiography; Electroencephalography; Female; Humans; Middle Aged; Multiple Sclerosis; Pain; Phenytoin; Placebos; Reflex; Spasm | 1968 |
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1983 |
Efficacy of baclofen in trigeminal neuralgia and some other painful conditions. A clinical trial.
Topics: Adult; Amputation Stumps; Baclofen; Carbamazepine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neuralgia; Phenytoin; Radiculopathy; Substance P; Tabes Dorsalis; Trigeminal Neuralgia | 1984 |
Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; History, 20th Century; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1983 |
Carbamazepine versus diphenylhydantoin in the treatment of myotonia.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Myotonic Dystrophy; Phenytoin | 1983 |
Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up.
Topics: Adult; Aged; Baclofen; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Time Factors; Trigeminal Neuralgia | 1984 |
A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults.
Topics: Adolescent; Adult; Aged; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenytoin; Seizures | 1983 |
Cinromide in epilepsy: a pilot study.
Topics: Adult; Carbamazepine; Cinnamates; Clinical Trials as Topic; Epilepsies, Partial; Female; Humans; Male; Phenytoin; Pilot Projects | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Controlled and comparative trials of valproate performed in Europe and Asia.
Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; Phenobarbital; Phenytoin; Seizures, Febrile; Valproic Acid | 1984 |
A randomised trial of strategies to improve patient compliance with anticonvulsant therapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Counseling; Drug Packaging; Epilepsy; Female; Humans; Male; Patient Compliance; Phenytoin; Random Allocation; Valproic Acid | 1984 |
Selective response to the anticonvulsant carbamazepine in manic-depressive illness: a case study.
Topics: Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Lithium; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Role of combination of valproic acid with diphenylhydantoin and carbamazepine in the management of intractable seizures.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Influence of dextropropoxyphene on steady state serum levels and protein binding of three anti-epileptic drugs in man.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Dextropropoxyphene; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 1980 |
Kinetics of phenobarbital in normal subjects and epileptic patients.
Topics: Administration, Oral; Adult; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Phenobarbital; Phenytoin | 1982 |
Water intoxication produced by carbamazepine and its reversal by phenytoin [proceedings].
Topics: Carbamazepine; Humans; Phenytoin; Water Intoxication | 1980 |
Comparing the cognitive effects of phenytoin and carbamazepine in long-term monotherapy: a two-year follow-up.
Topics: Adult; Affect; Carbamazepine; Cognition; Epilepsy; Female; Follow-Up Studies; Humans; Male; Neuropsychological Tests; Phenytoin; Psychiatric Status Rating Scales; Treatment Outcome | 1995 |
Anticonvulsant drugs for management of pain: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diabetic Neuropathies; Humans; Pain; Phenytoin; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 1995 |
Thyroid status of patients receiving long-term anticonvulsant therapy assessed by peripheral parameters: a placebo-controlled thyroxine therapy trial.
Topics: Adult; Age Distribution; Anticonvulsants; Carbamazepine; Comorbidity; Cross-Over Studies; Double-Blind Method; Epilepsy; Female; Humans; Hypothyroidism; Male; Phenytoin; Placebos; Sex Distribution; Thyroid Function Tests; Thyroid Hormones; Thyroxine | 1995 |
[Effects of phenytoin and cabamazepine on sex hormones in male patients with epilepsy: a controlled study].
Topics: Adolescent; Adult; Carbamazepine; Case-Control Studies; Epilepsy; Estradiol; Humans; Male; Phenytoin; Testosterone | 1994 |
Cognitive side-effects of phenytoin compared with carbamazepine in patients with localization-related epilepsy.
Topics: Adolescent; Adult; Attention; Carbamazepine; Cognition Disorders; Epilepsy; Female; Humans; Male; Memory; Middle Aged; Phenytoin; Prospective Studies; Reaction Time | 1994 |
Withdrawal of antiepileptic medication in children. Correlation of cognitive function and plasma concentration--the multicentre 'Holmfrid' study.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cognition; Humans; Phenytoin; Substance Withdrawal Syndrome; Valproic Acid | 1994 |
Renal tubular dysfunction following treatment with anti-epileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Ethosuximide; Humans; Infant; Kidney Function Tests; Kidney Tubules; Phenytoin; Valproic Acid | 1994 |
Flunarizine for treatment of partial seizures: results of a concentration-controlled trial.
Topics: Adolescent; Adult; Aged; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Flunarizine; Half-Life; Humans; Male; Middle Aged; Phenytoin; Treatment Outcome | 1994 |
[Clinical analysis of 72 epileptic patients treated with alkaline extract of Euphorbia fisheriana].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Drugs, Chinese Herbal; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Single-Blind Method | 1994 |
Determination of pharmacokinetic drug interactions with carbamazepine and phenytoin using stable isotope labeling and simple high-performance liquid chromatography/ultraviolet detection technique.
Topics: Administration, Oral; Analysis of Variance; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Drug Interactions; Humans; Isotope Labeling; Metabolic Clearance Rate; Phenytoin; Spectrophotometry, Ultraviolet | 1994 |
Neurobehavioral effects of phenytoin and carbamazepine in patients recovering from brain trauma: a comparative study.
Topics: Adult; Attention; Brain Injuries; Carbamazepine; Cognition; Double-Blind Method; Emotions; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Phenytoin; Placebos; Psychomotor Performance; Seizures | 1994 |
Dosage adjustments in response to monitored plasma concentrations: can unblinded staff adhere to objective criteria?
Topics: Attitude of Health Personnel; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Humans; Monitoring, Physiologic; Multicenter Studies as Topic; Observer Variation; Phenylcarbamates; Phenytoin; Placebos; Propylene Glycols; Randomized Controlled Trials as Topic; Retrospective Studies | 1994 |
A double-blind, placebo-controlled interaction study between oxcarbazepine and carbamazepine, sodium valproate and phenytoin in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin; Valproic Acid | 1994 |
Pure sensory seizures.
Topics: Carbamazepine; Cerebral Infarction; Electroencephalography; Epilepsies, Partial; Female; Functional Laterality; Humans; Hypesthesia; Magnetic Resonance Imaging; Middle Aged; Phenytoin; Single-Blind Method | 1993 |
Effects of phenytoin and carbamazepine on cognitive functions in newly diagnosed epileptic patients.
Topics: Adult; Carbamazepine; Cognition Disorders; Epilepsy; Female; Follow-Up Studies; Humans; Learning; Male; Memory Disorders; Phenytoin; Sex Factors; Task Performance and Analysis; Treatment Outcome | 1994 |
Carbamazepine and phenytoin in epilepsies refractory to barbiturates: efficacy, toxicity and mental function.
Topics: Adolescent; Adult; Affect; Carbamazepine; Child; Cognition; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies | 1993 |
Developmental and therapeutic pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Epilepsy; Female; Half-Life; Humans; Infant; Isoxazoles; Male; Phenytoin; Prospective Studies; Valproic Acid; Zonisamide | 1993 |
Withdrawal of antiepileptic medication in children--effects on cognitive function: The Multicenter Holmfrid Study.
Topics: Adolescent; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Female; Follow-Up Studies; Humans; Male; Memory Disorders; Neuropsychological Tests; Phenytoin; Valproic Acid | 1993 |
Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin or sodium valproate: a random trial.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Male; Mental Disorders; Mothers; Phenytoin; Psychological Tests; Valproic Acid | 1993 |
Effect of felbamate on carbamazepine and its major metabolites.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols | 1993 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbitone and phenytoin in healthy volunteers.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Quinine | 1993 |
Effect of plasma anticonvulsant level on pipecuronium-induced neuromuscular blockade: preliminary results.
Topics: Adult; Anesthesia; Anticonvulsants; Carbamazepine; Drug Interactions; Electrocardiography; Humans; Nerve Block; Neuromuscular Blocking Agents; Phenytoin; Pipecuronium; Sufentanil | 1995 |
A comparison of the OPUS and TDx analysers for antiepileptic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Female; Fluorescence Polarization Immunoassay; Humans; Immunoassay; Male; Phenobarbital; Phenytoin; Regression Analysis; Reproducibility of Results; Valproic Acid | 1995 |
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1996 |
Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychological Tests; Sleep Stages; Valproic Acid; Wakefulness | 1996 |
Systematic testing of medical intractability for carbamazepine, phenytoin, and phenobarbital or primidone in monotherapy for patients considered for epilepsy surgery.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Epilepsy; Follow-Up Studies; Humans; Infant; Middle Aged; Patient Selection; Phenobarbital; Phenytoin; Primidone; Quality of Life; Treatment Failure; Treatment Outcome | 1996 |
The effects of antiepileptic drugs on cognition in normal volunteers.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Cross-Over Studies; Double-Blind Method; Humans; Isoxazoles; Phenytoin; Valproic Acid; Wechsler Scales; Zonisamide | 1996 |
Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Male; Middle Aged; Phenobarbital; Phenytoin | 1996 |
Brainstem auditory evoked potentials in epileptics on different anti-epileptic drugs.
Topics: Acoustic Stimulation; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Evoked Potentials, Auditory, Brain Stem; Female; Functional Laterality; Humans; Phenobarbital; Phenytoin | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications.
Topics: Adult; Carbamazepine; Cohort Studies; Craniofacial Abnormalities; Epilepsy; Female; Fingers; Humans; Microcephaly; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies | 1997 |
Effects of pregnancy on various pathways of human antiepileptic drug metabolism.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications | 1997 |
A limited sampling method for the estimation of flunarizine area under the curve (AUC) and maximum plasma concentration (Cmax).
Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Drug Therapy, Combination; Flunarizine; Humans; Linear Models; Models, Biological; Models, Statistical; Phenytoin | 1997 |
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in adults with previously untreated epilepsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin | 1997 |
A double-blind controlled clinical trial of oxcarbazepine versus phenytoin in children and adolescents with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Double-Blind Method; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Male; Oxcarbazepine; Phenytoin | 1997 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Cognitive effects of anticonvulsant monotherapy in elderly patients: a placebo-controlled study.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cognition Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Valproic Acid | 1998 |
Antiepileptic drug treatment following temporal lobectomy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Cerebral Decortication; Clobazam; Combined Modality Therapy; Epilepsy, Temporal Lobe; Female; Follow-Up Studies; Humans; Male; Phenytoin; Prospective Studies | 1998 |
Clobazam has equivalent efficacy to carbamazepine and phenytoin as monotherapy for childhood epilepsy. Canadian Study Group for Childhood Epilepsy.
Topics: Adolescent; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clobazam; Cluster Analysis; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Female; Humans; Infant; Male; Patient Compliance; Phenytoin; Survival Analysis; Treatment Outcome | 1998 |
An active-control trial of lamotrigine monotherapy for partial seizures.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsies, Partial; Exanthema; Female; Humans; Hydrogen Peroxide; Lamotrigine; Male; Middle Aged; Phenytoin; Triazines; Valproic Acid | 1998 |
Antiepileptic drug therapy and sexual function in men with epilepsy.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Androgen-Binding Protein; Androstenedione; Anticonvulsants; Carbamazepine; Dehydroepiandrosterone; Drug Therapy, Combination; Educational Status; Epilepsy; Humans; Male; Marital Status; Middle Aged; Phenytoin; Sex Hormone-Binding Globulin; Sexual Behavior; Surveys and Questionnaires; Testosterone | 1999 |
Anti-epileptic drug intake adherence. The value of the blood drug level measurement and the clinical approach.
Topics: Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Drug Monitoring; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1998 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
Lack of pharmacokinetic drug interactions between tiagabine and carbamazepine or phenytoin.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dizziness; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; GABA Agonists; Headache; Humans; Male; Middle Aged; Nipecotic Acids; Phenytoin; Seizures; Sleep Stages; Tiagabine; Tremor | 1998 |
Spotlight on the continual applicability of routine plasma monitoring antiepileptic drugs in the treatment of epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Valproic Acid | 1999 |
The effect of anticonvulsant therapy on two doses of rocuronium-induced neuromuscular blockade.
Topics: Adult; Androstanols; Anesthesia, General; Anesthetics, General; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgical Procedures; Phenytoin; Rocuronium | 1999 |
Safety and tolerability of gabapentin as adjunctive therapy in a large, multicenter study.
Topics: Acetates; Adolescent; Adult; Ambulatory Care; Amines; Anticonvulsants; Asthenia; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1999 |
Gabapentin as adjunctive therapy for partial seizures.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dizziness; Drug Administration Schedule; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Patient Dropouts; Phenytoin; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin.
Topics: Anticonvulsants; Body Weight; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Nipecotic Acids; Phenytoin; Tiagabine; Weight Gain | 2000 |
Topiramate in refractory epilepsy: a prospective observational study.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Prospective Studies; Topiramate; Treatment Outcome; Triazines | 2000 |
Influence of vitamin D administration on bone ultrasound measurements in patients on anticonvulsant therapy.
Topics: 25-Hydroxyvitamin D 2; Adult; Aged; Anticonvulsants; Bone and Bones; Calcifediol; Carbamazepine; Epilepsy; Female; Fingers; Humans; Male; Middle Aged; Osteomalacia; Parathyroid Hormone; Phenytoin; Ultrasonography; Valproic Acid; Vitamin D | 2000 |
Tiagabine versus phenytoin and carbamazepine as add-on therapies: effects on abilities, adjustment, and mood.
Topics: Adaptation, Psychological; Adult; Affect; Anticonvulsants; Carbamazepine; Cognition; Double-Blind Method; Epilepsy, Complex Partial; Female; Humans; Male; Middle Aged; Nipecotic Acids; Phenytoin; Statistics, Nonparametric; Tiagabine | 2000 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin | 2000 |
The short-term impact of adjunctive tiagabine on health-related quality of life.
Topics: Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsy, Complex Partial; Female; Health Status; Health Status Indicators; Humans; Male; Neuropsychological Tests; Nipecotic Acids; Phenytoin; Quality of Life; Surveys and Questionnaires; Tiagabine; Treatment Outcome | 2001 |
Catatonia: an open prospective series with carbamazepine.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Carbamazepine; Catatonia; Female; Humans; Lorazepam; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Prospective Studies; Psychiatric Status Rating Scales | 2001 |
Add-on phenytoin fails to prevent early seizures after surgery for supratentorial brain tumors: a randomized controlled study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Neoplasms; Craniotomy; Female; Humans; Incidence; Intraoperative Care; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Care; Risk Factors; Seizures | 2002 |
Remacemide hydrochloride as an add-on therapy in epilepsy: a randomized, placebo-controlled trial of three dose levels (300, 600 and 800 mg/day) in a B.I.D. regimen.
Topics: Acetamides; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Phenytoin | 2002 |
Remacemide hydrochloride as an add-on therapy in epilepsy: a randomized, placebo-controlled trial of three dose levels (300, 600 and 1200 mg/day) in a Q.I.D. regimen.
Topics: Acetamides; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Phenytoin; Statistics, Nonparametric | 2002 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis.
Topics: Adult; Albendazole; Anthelmintics; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Female; Humans; Isomerism; Male; Neurocysticercosis; Phenobarbital; Phenytoin | 2002 |
Seizure reduction and quality of life improvements in people with epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Attitude to Health; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Follow-Up Studies; Health Status; Humans; Male; Middle Aged; Personality Inventory; Phenytoin; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Vigabatrin | 2002 |
Time course of lamotrigine de-induction: impact of step-wise withdrawal of carbamazepine or phenytoin.
Topics: Adolescent; Adult; Aged; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenytoin; Retrospective Studies; Substance Withdrawal Syndrome; Triazines | 2002 |
Acute symptomatic seizures due to single CT lesions: how long to treat with antiepileptic drugs?
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Brain Diseases; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Phenytoin; Seizures; Tomography, X-Ray Computed | 2002 |
Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report.
Topics: Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Glioma; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Multidrug Resistance-Associated Protein 2; Phenytoin; Probability; Prognosis; Survival Rate; Treatment Outcome | 2002 |
Apparent increase in type I 5'-deiodinase activity induced by antiepileptic medication in mentally retarded subjects.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Hormones; Humans; Intellectual Disability; Iodide Peroxidase; Male; Phenytoin; Seizures; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine, Reverse | 2002 |
Microdialysis sampling of carbamazepine, phenytoin and phenobarbital in subcutaneous extracellular fluid and subdural cerebrospinal fluid in humans: an in vitro and in vivo study of adsorption to the sampling device.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Extracellular Space; Female; Humans; Male; Microdialysis; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 2002 |
Quality of life improvement with conversion to lamotrigine monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Satisfaction; Phenytoin; Quality of Life; Sick Role; Substance Withdrawal Syndrome; Triazines | 2004 |
Increased depressant effect of phenytoin sodium as compared to carbamazepine on cortical excitability: a transcranial magnetic evaluation.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Magnetoencephalography; Male; Phenytoin | 2004 |
Effects of oxcarbazepine and phenytoin on the EEG and cognition in healthy volunteers.
Topics: Adolescent; Adult; Affect; Anticonvulsants; Carbamazepine; Cognition; Double-Blind Method; Electroencephalography; Humans; Middle Aged; Neuropsychological Tests; Oxcarbazepine; Phenytoin; Psychomotor Performance; Reaction Time; Regression Analysis | 2004 |
A comparison of anticonvulsants in the treatment of impulsive aggression.
Topics: Adult; Aggression; Anticonvulsants; Carbamazepine; Double-Blind Method; Female; Humans; Impulsive Behavior; Intelligence Tests; Male; Phenytoin; Psychiatric Status Rating Scales; Valproic Acid | 2005 |
Differential effects of antiepileptic drugs on sexual function and hormones in men with epilepsy.
Topics: Adolescent; Adult; Age Factors; Aging; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Down-Regulation; Epilepsy; Estradiol; Gonadal Steroid Hormones; Humans; Lamotrigine; Luteinizing Hormone; Male; Middle Aged; Phenytoin; Sex Hormone-Binding Globulin; Sexual Dysfunction, Physiological; Testosterone; Triazines | 2005 |
Evaluation of antiepileptic drugs in pregnancy in a Jordanian army hospital.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Clinical Protocols; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Hospitals, Military; Humans; Incidence; Jordan; Phenytoin; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Care; Risk Factors; Treatment Outcome | 2005 |
In utero antiepileptic drug exposure: fetal death and malformations.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Cognition; Female; Fetal Death; Humans; Lamotrigine; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Triazines; Uterus; Valproic Acid | 2006 |
Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Algorithms; Analysis of Variance; Antineoplastic Agents, Hormonal; Carbamazepine; Creatinine; Dexamethasone; Female; Humans; Injections, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Phenytoin; Retrospective Studies; Serum Albumin; Tissue Distribution; Valproic Acid | 2006 |
Chronotherapeutic dose schedule of phenytoin and carbamazepine in epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chronotherapy; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 2006 |
Albendazole therapy for single small enhancing CT lesions (SSECTL) in the brain in epilepsy.
Topics: Adolescent; Adult; Albendazole; Anthelmintics; Carbamazepine; Cerebral Cortex; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Middle Aged; Neurocysticercosis; Phenytoin; Prospective Studies; Recurrence; Seizures; Tomography, X-Ray Computed | 2008 |
Population pharmacokinetics of carbamazepine in elderly patients.
Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Phenytoin; Prospective Studies; Tissue Distribution | 2012 |
Interaction profile of Zizyphus jujuba with phenytoin, phenobarbitone, and carbamazepine in maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Fruit; Glutathione; Lipid Peroxidation; Male; Maze Learning; Phenobarbital; Phenytoin; Phytotherapy; Rats; Rats, Wistar; Seizures; Ziziphus | 2012 |
Usefulness of salivary drug monitoring for detecting efflux transporter overexpression.
Topics: Adult; Anticonvulsants; Area Under Curve; Biological Availability; Carbamazepine; Drug Monitoring; Female; Humans; Male; Metabolic Clearance Rate; Phenytoin; Saliva; Sex Characteristics | 2013 |
Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Drug Interactions; Enzyme Induction; Female; Glioma; Glucuronates; Humans; Irinotecan; Male; Middle Aged; Phenobarbital; Phenytoin | 2015 |
AntiEpileptic drug Monitoring in PREgnancy (EMPiRE): a double-blind randomised trial on effectiveness and acceptability of monitoring strategies.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Monitoring; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Quality of Life; Seizures; United Kingdom | 2018 |
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Topics: Adolescent; Adult; Anticonvulsants; C-Reactive Protein; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Nitriles; Phenobarbital; Phenytoin; Pyridones; Time Factors; Young Adult | 2018 |
1395 other study(ies) available for phenytoin and carbamazepine
| Article | Year |
|---|---|
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
Topics: Administration, Oral; Animals; Anticonvulsants; Benzhydryl Compounds; Blood-Brain Barrier; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Mice; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Proline; Rats; Structure-Activity Relationship | 1992 |
Synthesis and anticonvulsant activity of enaminones.
Topics: Amines; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electric Stimulation; Kindling, Neurologic; Male; Mice; Rats; Seizures; Structure-Activity Relationship | 1992 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
6-Alkyl-N,N-disubstituted-2-pyridinamines as anticonvulsant agents.
Topics: Aminopyridines; Animals; Ataxia; Blepharoptosis; Chemical Phenomena; Chemistry; Electroshock; Kindling, Neurologic; Male; Mice; Molecular Structure; Motor Activity; Rats; Seizures; Structure-Activity Relationship | 1989 |
Anticonvulsant activities of phenyl-substituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel.
Topics: Animals; Anticonvulsants; Binding Sites; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Cerebral Cortex; Drug Evaluation, Preclinical; Mice; Neurons; Oxazoles; Sodium Channels; Structure-Activity Relationship; Synaptosomes | 1988 |
A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Body Temperature Regulation; Brain; Electroshock; Exploratory Behavior; Homovanillic Acid; Hypothermia; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Seizures; Structure-Activity Relationship | 1988 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 3. Guanidines.
Topics: Animals; Chemical Phenomena; Chemistry; Electroshock; Guanidines; Mice; Pentylenetetrazole; Rats; Seizures; Thiadiazoles | 1987 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 1. Hydrazines.
Topics: Animals; Anticonvulsants; Hydrazines; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 2. Aminoalkyl derivatives.
Topics: Animals; Anticonvulsants; Mice; Rats; Structure-Activity Relationship; Thiadiazoles | 1986 |
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Motor Skills; Papio; Pentylenetetrazole; Photic Stimulation; Pyridazines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1986 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Substituted (omega-aminoalkoxy) stilbene derivatives as a new class of anticonvulsants.
Topics: Animals; Anticonvulsants; Biological Assay; Drug Evaluation, Preclinical; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Stilbenes; Structure-Activity Relationship | 1984 |
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
Synthesis and anticonvulsant properties of new benzylpyridazine derivatives.
Topics: Animals; Anticonvulsants; Lamotrigine; Male; Mice; Molecular Conformation; Pyridazines; Structure-Activity Relationship; Triazines | 1994 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
(Aryloxy)aryl semicarbazones and related compounds: a novel class of anticonvulsant agents possessing high activity in the maximal electroshock screen.
Topics: Animals; Anticonvulsants; Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Hydrogen Bonding; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 1996 |
Aroyl(aminoacyl)pyrroles, a new class of anticonvulsant agents.
Topics: Anesthesia; Animals; Anticonvulsants; Bicuculline; Calcium; Cerebellum; Electroshock; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Piperidines; Potassium; Pyrroles; Rats; Seizures; Structure-Activity Relationship; Veratridine | 1997 |
Synthesis, anticonvulsant activity, and structure-activity relationships of sodium channel blocking 3-aminopyrroles.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Indicators and Reagents; Male; Mice; Models, Molecular; Molecular Structure; Motor Activity; Neurotoxins; Pentylenetetrazole; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Sodium Channel Blockers; Structure-Activity Relationship | 1998 |
Synthesis and anticonvulsant activity of a new class of 2-[(arylalky)amino]alkanamide derivatives.
Topics: Alanine; Animals; Anticonvulsants; Benzylamines; Bicuculline; Drug Design; Electroshock; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Structure; Motor Activity; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine | 1998 |
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
Topics: Animals; Anticonvulsants; Electric Stimulation; Injections, Intraperitoneal; Male; Mice; Oxazoles; Rats; Seizures; Thiazoles | 1998 |
Comparative molecular field analysis of hydantoin binding to the neuronal voltage-dependent sodium channel.
Topics: Amides; Animals; Anticonvulsants; Cerebral Cortex; Hydantoins; Ion Channel Gating; Least-Squares Analysis; Ligands; Models, Molecular; Molecular Conformation; Neurons; Rats; Sodium Channels; Structure-Activity Relationship; Synaptosomes | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
Topics: Analgesics; Animals; Cell Line; Humans; Male; Pain; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Structure-Activity Relationship | 2004 |
Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Mice; Neurotoxicity Syndromes; Quinolines; Seizures; Structure-Activity Relationship | 2005 |
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver Injury; Drug Design; Female; gamma-Aminobutyric Acid; Male; Mice; Models, Molecular; Motor Activity; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.
Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Carbamazepine; Cell Line; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression; Humans; Levetiracetam; Mice; Phenytoin; Piracetam; Transfection | 2007 |
Synthesis and anticonvulsant activity of sulfonamide derivatives-hydrophobic domain.
Topics: Animals; Anticonvulsants; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides | 2007 |
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.
Topics: Acetazolamide; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Sulfonamides | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.
Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Drug Design; Electroshock; Mice; Pentylenetetrazole; Quinazolinones; Rats; Thiadiazoles | 2008 |
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Semicarbazones; Structure-Activity Relationship; Touch | 2007 |
Synthesis and anticonvulsant activity of some novel 3-aryl amino/amino-4-aryl-5-imino-Delta2-1,2,4-thiadiazoline.
Topics: Animals; Anticonvulsants; Electroshock; Immobility Response, Tonic; Injections, Intraperitoneal; Male; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Structure-Activity Relationship; Thiazolidines | 2008 |
N-{[(6-substituted-1,3-benzothiazole-2-yl)amino]carbonothioyl}-2/4-substituted benzamides: synthesis and pharmacological evaluation.
Topics: Animals; Anticonvulsants; Benzamides; Benzothiazoles; Central Nervous System Depressants; Chemical and Drug Induced Liver Injury; Liver Function Tests; Male; Mice; Rats; Rats, Wistar; Seizures; Structure-Activity Relationship; Sulfides | 2008 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Synthesis of novel 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Benzoxazines; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred C57BL; Spectrophotometry, Infrared | 2008 |
CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.
Topics: Animals; Anticonvulsants; Central Nervous System Depressants; Drug Design; Male; Mice; Motor Activity; Quinazolinones; Rats | 2008 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Central Nervous System; Computer Simulation; Electroshock; Humans; Isoenzymes; Male; Mice; Mice, Inbred Strains; Models, Animal; Models, Chemical; Molecular Structure; Recombinant Proteins; Reproducibility of Results; Seizures; Stereoisomerism; Structure-Activity Relationship | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Anticonvulsant activity of some xanthone derivatives.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Xanthones | 2008 |
Synthesis and anticonvulsant activity of some substituted 1,2,4-thiadiazoles.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Mice; Rats; Spectrophotometry, Infrared; Thiadiazoles | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models.
Topics: Animals; Anticonvulsants; Benzodiazepines; Convulsants; Hippocampus; Kindling, Neurologic; Ligands; Mice; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Structure-Activity Relationship | 2009 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: advancement of N-((benzo[b]thien-3-yl)methyl)sulfamide (JNJ-26990990) into human clinical studies.
Topics: Amides; Animals; Anticonvulsants; Carbonic Anhydrase II; Cell Line; Clinical Trials as Topic; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Rats; Sulfonamides; Thiophenes | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Depressants; Male; Mice; Molecular Structure; Pentylenetetrazole; Quinazolinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Structure-Activity Relationship; Urea | 2009 |
Synthesis, anticonvulsant activity and 3D-QSAR study of some prop-2-eneamido and 1-acetyl-pyrazolin derivatives of aminobenzothiazole.
Topics: Alanine Transaminase; Alkenes; Animals; Anticonvulsants; Aspartate Aminotransferases; Behavior, Animal; Benzothiazoles; Female; Liver; Male; Mice; Models, Molecular; Molecular Conformation; Pyrazoles; Quantitative Structure-Activity Relationship; Rats; Software | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.
Topics: Animals; Anticonvulsants; Drug Design; Electroconvulsive Therapy; Lethal Dose 50; Mice; Triazoles | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Combating oxidative stress in epilepsy: design, synthesis, quantum chemical studies and anticonvulsant evaluation of 1-(substituted benzylidene/ethylidene)-4-(naphthalen-1-yl)semicarbazides.
Topics: Animals; Anticonvulsants; Antioxidants; Benzylidene Compounds; Drug Design; Electrons; Epilepsy; Male; Mice; Oxidative Stress; Quantum Theory; Semicarbazides | 2010 |
Design and synthesis of 10-alkoxy-5, 6-dihydro-triazolo[4,3-d]benzo[f][1,4]oxazepine derivatives with anticonvulsant activity.
Topics: Animals; Anticonvulsants; Central Nervous System; Drug Design; Mice; Oxazepines; Oxygen; Seizures; Spectrum Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles: one more step towards establishing four binding site pharmacophoric model hypothesis for anticonvulsant activity.
Topics: Animals; Anticonvulsants; Binding Sites; Models, Molecular; Oxadiazoles; Rats; Semicarbazones | 2010 |
Design & synthesis of 2-(substituted aryloxy)-5-(substituted benzylidene)-3-phenyl-2,5-dihydro-1H-[1,2,4] triazin-6-one as potential anticonvulsant agents.
Topics: Animals; Anticonvulsants; Behavior, Animal; Drug Design; Electroshock; Male; Mice; Nervous System; Pentylenetetrazole; Seizures; Triazines | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
Synthesis and anticonvulsant activity of 7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones and their derivatives.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Electroshock; Isoniazid; Mice; Pentylenetetrazole; Pyrimidinones; Seizures; Semicarbazides; Structure-Activity Relationship; Triazoles | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogs.
Topics: Acetamides; Animals; Anticonvulsants; Boron Compounds; Cyclohexanes; Dose-Response Relationship, Drug; Electric Stimulation; Magnetic Resonance Spectroscopy; Male; Mice; Phthalimides; Rats; Spectrometry, Mass, Electrospray Ionization | 2011 |
Synthesis and anticonvulsant activity of trans- and cis-2-(2,6-dimethylphenoxy)-N-(2- or 4-hydroxycyclohexyl)acetamides and their amine analogs.
Topics: Acetamides; Amines; Animals; Anticonvulsants; Mice; Rats; Seizures | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Design and synthesis of 3,5-diarylpiperidin-2,6-diones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Electroshock; Mice; Molecular Structure; Movement Disorders; Piperidines; Seizures; Stereoisomerism | 2012 |
Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Biological Assay; Electroshock; Heptanes; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Quinolines; Seizures; Spiro Compounds; Structure-Activity Relationship; Toxicity Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Synthesis of some novel 1-(2-naphthyl)-2-(imidazol-1-yl)ethanone oxime ester derivatives and evaluation of their anticonvulsant activity.
Topics: Animals; Anticonvulsants; Electroshock; Esters; Imidazoles; Isomerism; Mice; Motor Activity; Naphazoline; Neuropsychological Tests; Oximes; Seizures; Structure-Activity Relationship | 2012 |
Design, synthesis and evaluation of N-(substituted benzothiazol-2-yl)amides as anticonvulsant and neuroprotective.
Topics: Acrylamide; Amides; Animals; Anticonvulsants; Benzothiazoles; Brain; Dose-Response Relationship, Drug; Drug Design; Female; Male; Mice; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Swimming | 2012 |
Novel limonene and citral based 2,5-disubstituted-1,3,4-oxadiazoles: a natural product coupled approach to semicarbazones for antiepileptic activity.
Topics: Acyclic Monoterpenes; Animals; Anticonvulsants; Binding Sites; Cyclohexenes; Disease Models, Animal; gamma-Aminobutyric Acid; Limonene; Monoterpenes; Oxadiazoles; Protein Binding; Rats; Seizures; Semicarbazones; Structure-Activity Relationship; Terpenes | 2013 |
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: a hybrid pharmacophore approach.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Seizures; Thiazoles; Thioamides | 2013 |
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).
Topics: Absorption; Amides; Animals; Anticonvulsants; Dioxanes; Dogs; Drug Evaluation, Preclinical; Drug Resistance; Epilepsy; Female; Humans; Male; Mice; Rats; Sulfonamides | 2013 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Discovery of benzothiazine derivatives as novel, orally-active anti-epileptic drug candidates with broad anticonvulsant effect.
Topics: Administration, Oral; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Electroshock; Epilepsy; Injections, Subcutaneous; Kindling, Neurologic; Mice; Molecular Structure; Pentylenetetrazole; Rats; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
New (arylalkyl)azole derivatives showing anticonvulsant effects could have VGSC and/or GABA
Topics: Animals; Anticonvulsants; Azoles; Calcium Channels; Drug Design; Male; Mice; Molecular Docking Simulation; Porosity; Protein Binding; Protein Conformation; Receptors, GABA-A; Seizures | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Novel benzothiazole hydrazine carboxamide hybrid scaffolds as potential in vitro GABA AT enzyme inhibitors: Synthesis, molecular docking and antiepileptic evaluation.
Topics: Anticonvulsants; Hydrazines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2019 |
A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays.
Topics: Animals; Chlorocebus aethiops; Dengue Virus; Dose-Response Relationship, Drug; Genes, Reporter; HeLa Cells; Humans; Protease Inhibitors; Vero Cells; Virus Replication; West Nile virus | 2020 |
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture.
Topics: Animals; Benzamides; Cell Survival; Dengue Virus; Drug Stability; Genes, Reporter; HeLa Cells; Humans; Microsomes, Liver; Protease Inhibitors; Rats; Small Molecule Libraries; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2021 |
[Adverse effects of anti-epileptic drugs].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mephenytoin; Nitrazepam; Phenytoin; Primidone; Succinimides; Thiazines; Trimethadione; Valproic Acid | 1975 |
Interactions between anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
Resistant transitory epilepsy in children.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Child, Preschool; Encephalomyelitis, Acute Disseminated; Epilepsy; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Phenytoin; Smallpox Vaccine; Thiazines | 1976 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Measurement of anti-epileptic drugs in plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Phenobarbital; Phenytoin; Primidone; Quality Control; Thiazines | 1977 |
The extraction of antiepileptic drugs. Model study on partition coefficients.
Topics: Anticonvulsants; Carbamazepine; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Solvents; Spectrum Analysis | 1978 |
[The coincidence of visceral lupus erythematosus and epilepsy].
Topics: Adolescent; Carbamazepine; Epilepsy, Tonic-Clonic; Humans; Lupus Erythematosus, Systemic; Male; Phenytoin; Prednisolone; Primidone; Thiazines | 1978 |
Anticonvulsant therapy and serum gamma-glutamyl-transferase.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Kinetics; Male; Middle Aged; Phenytoin; Primidone; Sex Factors; Time Factors | 1978 |
Excretion of antiepileptic drugs in sweat.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Phenobarbital; Phenytoin; Sweat; Temperature | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Neuropsychological correlates of anticonvulsants and epileptiform discharges in adult epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Phenytoin; Psychological Tests; Thiazines | 1978 |
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital | 1979 |
Letter: Bioavailability of drugs after intramuscular injection.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Biotransformation; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Injections, Intramuscular; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
Tic doloureux.
Topics: Carbamazepine; Chlorpromazine; Humans; Male; Phenytoin; Trigeminal Neuralgia | 1975 |
Effects of anticonvulsant drugs on thyroid hormones in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Primidone; Protein Binding; Thyroid Function Tests; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1978 |
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digitoxin; Drug Interactions; Female; Humans; Male; Oxacillin; Phenobarbital; Phenytoin; Pregnancy; Vitamin D | 1979 |
Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.
Topics: Acute Disease; Adult; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy, Post-Traumatic; Humans; Male; Phenytoin; Porphyrias | 1978 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Carbamazepine in childhood seizures.
Topics: Barbiturates; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Seizures | 1978 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
Relationships between plasma concentrations of diphenylhydantoin, phenobarbital, carbamazepine, and 3-sulfamoylmethyl-1,2-benzisoxazole (AD-810), a new anticonvulsant agent, and their anticonvulsant or neurotoxic effects in experimental animals.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dogs; Dose-Response Relationship, Drug; Haplorhini; Isoxazoles; Male; Mice; Motor Skills; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Rats; Seizures; Species Specificity | 1979 |
Facilitation of opiate- and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine.
Topics: Animals; Carbamazepine; Drug Synergism; Endorphins; Enkephalins; Habituation, Psychophysiologic; Male; Mice; Morphine; Motor Activity; Narcotics; Phenytoin; Time Factors | 1979 |
Bone mineral content in epileptics.
Topics: Aged; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Minerals; Muscle Contraction; Muscle Tonus; Osteomalacia; Phenobarbital; Phenytoin | 1979 |
Effect of convulsions and anticonvulsive drugs on cerebrospinal fluid cyclic AMP in rabbits.
Topics: Animals; Aspartate Aminotransferases; Carbamazepine; Cyclic AMP; Depression, Chemical; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures | 1976 |
Prophylactic effects of phenytoin, phenobarbital, and carbamazepine examined in kindling cat preparations.
Topics: Animals; Carbamazepine; Cats; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsy; Male; Phenobarbital; Phenytoin; Seizures; Synaptic Transmission | 1976 |
Autonomous peripheral nerve activity causing generalized muscle stiffness and fasciculations: report of a case with physiological, pharmacological, and morphological observations.
Topics: Adolescent; Anesthesia, General; Anesthesia, Spinal; Arm; Carbamazepine; Curare; Electromyography; Humans; Leg; Male; Muscles; Nerve Block; Neural Conduction; Neuromuscular Diseases; Peripheral Nerves; Peripheral Nervous System Diseases; Phenytoin; Ulnar Nerve | 1976 |
Cyclic AMP accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital, and phenytoin.
Topics: Adenosine; Animals; Brain Chemistry; Carbamazepine; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Ouabain; Phenobarbital; Phenytoin; Rats | 1977 |
Photosensitive epilepsy in Papio papio as a model for drug studies.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Haplorhini; Papio; Phenytoin; Photic Stimulation; Seizures; Serotonin; Synaptic Transmission | 1978 |
Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Clonazepam; Cyclic AMP; Diazepam; Dopamine; Male; Norepinephrine; Phenobarbital; Phenytoin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 1979 |
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures | 1979 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
Antiepileptic drugs: biotransformation, metabolism, and serum half-life.
Topics: Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Biotransformation; Carbamazepine; Half-Life; Humans; Hydantoins; Oxazoles; Phenylurea Compounds; Phenytoin; Primidone; Succinimides; Sulfonamides | 1975 |
[Effects of combination of anti-epileptic drugs].
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents | 1975 |
Antipyretic analgesics in patients on antiepileptic drug therapy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Drug Interactions; Epilepsy; Female; Humans; Male; Phenytoin; Protein Binding | 1979 |
[Drug therapy of epilepsy].
Topics: Age Factors; Anticonvulsants; Barbiturates; Benzodiazepines; Bromides; Carbamazepine; Chlormethiazole; Contraceptives, Oral; Diabetes Mellitus; Enzyme Induction; Epilepsy; Female; Humans; Kidney Failure, Chronic; Lactation; Microsomes, Liver; Phenytoin; Postpartum Period; Pregnancy; Valproic Acid | 1977 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Deposits of plasma proteins in the skin during treatment with carbamazepine and diphenylhydantoin.
Topics: Adult; Aged; Blood Proteins; Carbamazepine; Epilepsy; Female; Fluorescent Antibody Technique; Humans; Immunoglobulins; Male; Middle Aged; Phenytoin; Skin | 1977 |
Epilepsy and IgA deficiency--the effect of sodium valproate.
Topics: Adult; Agammaglobulinemia; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Male; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid | 1977 |
Thyroid function tests in patients on long-term treatment with various anticonvulsant drugs.
Topics: Adolescent; Adult; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1978 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Humans; Microchemistry; Nordazepam; Phenobarbital; Phenytoin | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Enzyme multiplied immunoassay of phenytoin and carbamazepine using the Centrifichem analyser.
Topics: Autoanalysis; Carbamazepine; Chromatography, Gas; Immunoenzyme Techniques; Phenytoin | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Study of the EMIT method for determination of anti-epileptic drugs in serum using an LKB 2086 reaction rate analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1978 |
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex | 1979 |
Valproic acid binding to human serum albumin and determination of free fraction in the presence of anticonvulsants and free fatty acids.
Topics: Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Humans; Linoleic Acids; Oleic Acids; Palmitic Acids; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Stearic Acids; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
The drug of choice for major seizures?
Topics: Carbamazepine; Decision Making; Humans; Phenytoin; Seizures; Valproic Acid | 1979 |
The therapeutic underpriviledged.
Topics: Carbamazepine; Child; Dosage Forms; Drug Administration Schedule; Humans; Phenytoin; Valproic Acid | 1979 |
Anticonvulsant therapy in childhood. Recent advances.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
High pressure liquid chromatography for simultaneous analysis of anticonvulsants: comparison with EMIT system.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1979 |
Distribution of anticonvulsant drugs in gray and white matter of human brain.
Topics: Anticonvulsants; Brain; Carbamazepine; Epilepsies, Partial; Humans; Mesencephalon; Nervous System; Phenobarbital; Phenytoin; Spinal Cord | 1977 |
Effect of anticonvulsants on cortical focal seizure in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid | 1977 |
[Changes in the thyroid hormone system with combined anticonvulsion treatment of epileptic children and adolescents (author's transl)].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Cholesterol; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Humans; Iodine; Liver; Phenytoin; Primidone; Protein Binding; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins | 1977 |
Mental dullness associated with left frontal continuous focal discharge.
Topics: Adult; Carbamazepine; Cognition Disorders; Electroencephalography; Epilepsy, Post-Traumatic; Frontal Lobe; Humans; Male; Phenobarbital; Phenytoin; Syndrome | 1977 |
Medical treatment of epilepsy: part I.
Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Female; Humans; Infant; Phenobarbital; Phenytoin; Recurrence | 1978 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Seizures; Seizures, Febrile | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; Liver; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1979 |
The treatment of tinnitus with oral anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Carbamazepine; Female; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Time Factors; Tinnitus | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Primidone | 1979 |
Organic personality disturbance: a case of apparent atypical cyclic affective disorder.
Topics: Adult; Bipolar Disorder; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Personality Disorders; Phenytoin; Religion and Psychology | 1979 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome | 1979 |
One drug for epilepsy [proceedings].
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin | 1979 |
[Conservative therapy of trigeminal neuralgia].
Topics: Carbamazepine; Drug Therapy, Combination; Humans; Phenytoin; Trigeminal Neuralgia | 1979 |
Serum phenytoin, phenobarbital, carbamazepine, albumin; and plasma estradiol, progesterone concentrations during the menstrual cycle in women with epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Menstruation; Phenobarbital; Phenytoin; Progesterone; Serum Albumin | 1979 |
Schizophrenia-like psychosis associated with anticonvulsant toxicity.
Topics: Adult; Anticonvulsants; Athetosis; Carbamazepine; Chorea; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Psychoses, Substance-Induced; Schizophrenia | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
Drugs for epilepsy.
Topics: Carbamazepine; Epilepsy; Humans; Phenytoin | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Pharmacokinetic and pharmacodynamic tolerance of a new anticonvulsant agent (3-sulfamoylmethyl-1,2-benzisoxazole) compared to phenobarbital, diphenylhydantoin and carbamazepine in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Hexobarbital; Isoxazoles; Kinetics; Male; Oxazoles; Phenobarbital; Phenytoin; Proadifen; Rats; Sleep; Time Factors | 1979 |
Phenytoin and carbamazepine in production of cleft palates in mice. Comparison of teratogenic effects.
Topics: Animals; Carbamazepine; Cleft Palate; Dose-Response Relationship, Drug; Female; Mice; Phenytoin; Pregnancy | 1979 |
Continuous muscle fiber activity: a case with unusual clinical features.
Topics: Aged; Carbamazepine; Female; Humans; Motor Activity; Muscular Diseases; Phenytoin; Tubocurarine | 1979 |
[Studies on the serum levels of the antiepileptic drugs-with particular reference to diphenylhydantoin, phenobarbital and carbamazepine-(author's transl)].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin | 1979 |
[Studies on the separation and photometric determination of antiepileptics (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Mephobarbital; Methods; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1979 |
The epoxide of carbamazepine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Biotransformation; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Methods; Middle Aged; Phenytoin | 1979 |
Flashing pain syndrome.
Topics: Animals; Carbamazepine; Pain; Phenytoin; Primidone; Rats; Syndrome | 1977 |
Effect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Sex Factors; Sex Hormone-Binding Globulin; Testosterone | 1978 |
Isaacs syndrome with laryngeal involvement: an unusual presentation of myokymia.
Topics: Action Potentials; Adolescent; Adult; Carbamazepine; Dyspnea; Electromyography; Female; Hoarseness; Humans; Laryngeal Muscles; Neuromuscular Blocking Agents; Neuromuscular Diseases; Phenytoin; Ulnar Nerve | 1979 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
Medical treatment of trigeminal neuralgia.
Topics: Carbamazepine; Chlorphenesin; Humans; Phenytoin; Trigeminal Neuralgia | 1977 |
[Neuromyotonia syndrome (author's transl)].
Topics: Aged; Biopsy; Carbamazepine; Electromyography; Female; Humans; Microscopy, Electron; Muscles; Neuromuscular Diseases; Phenytoin; Syndrome | 1977 |
[Selected clinical aspects of routine monitoring of anticonvulsant concentrations in serum (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Chromatography, Gas; Drug Therapy, Combination; Ethosuximide; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin | 1977 |
[A study on anticonvulsant level in body fluid. Ist report: serum level and drug interaction (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Factors influencing plasma carbamazepine concentrations.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Male; Mephobarbital; Middle Aged; Phenobarbital; Phenytoin | 1977 |
Carbamazepine-induced syndrome of inappropriate antidiuretic hormone secretion. Reversal by concomitant phenytoin therapy.
Topics: Aged; Carbamazepine; Diuresis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hyponatremia; Phenytoin; Syndrome; Trigeminal Neuralgia; Vasopressins | 1978 |
Kinetics of carbamazepine and carbamazepine-epoxide, determined by use of plasma and saliva.
Topics: Adolescent; Adult; Carbamazepine; Drug Interactions; Epoxy Compounds; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Saliva | 1978 |
What to do about tic douloureux.
Topics: Carbamazepine; Humans; Methods; Nerve Block; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1978 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
[Optimizing the therapeutic process in long-term antiepileptic therapy through the determination of drug levels in patients].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy; Epilepsy; Ethosuximide; Germany, East; Humans; Methods; Phenobarbital; Phenytoin | 1978 |
Anticonvulsants and thyroid function.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1978 |
[A study on anticonvulsant level in body fluids. 2nd report: Dialyzed serum (free form), CSF and saliva level (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Simultaneous gas chromatographic determination of diphenylhydantoin, carbamazepin (Tegretol), phenobarbital and primidone in presence of Kemadrin (procyclidine) and Prolixin (fluphenazine) in plasma of psychiatric patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Fluphenazine; Humans; Mental Disorders; Methods; Phenobarbital; Phenytoin; Primidone; Procyclidine; Pyrrolidines | 1978 |
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone | 1978 |
Seizure susceptibility and anticonvulsant activity of carbamazepine, diphenylhydantoin and phenobarbital in rats with selective depletions of brain monoamines.
Topics: Animals; Anticonvulsants; Biogenic Amines; Brain; Carbamazepine; Electroshock; Female; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Seizures | 1978 |
Improved gas-chromatographic analysis for anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1978 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Salicylates | 1978 |
Carbamazepine, carbamazepine-10,11-epoxide and phenytoin concentrations in brain tissue of epileptic children.
Topics: Brain; Carbamazepine; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; Psychosurgery; Temporal Lobe | 1978 |
[Isaacs' disease (continuous muscle fiber activity)].
Topics: Adult; Basal Metabolism; Carbamazepine; Electromyography; Humans; Male; Muscular Diseases; Neural Conduction; Peroneal Nerve; Phenytoin; Syndrome; Ulnar Nerve | 1978 |
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients.
Topics: Adolescent; Brain; Carbamazepine; Child; Epilepsy; Epoxy Compounds; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1978 |
Three cases of sinoatrial block induced by anticonvulsants.
Topics: Aged; Anticonvulsants; Carbamazepine; Electrocardiography; Female; Heart Block; Humans; Male; Phenytoin; Sinoatrial Block | 1978 |
Downbeat nystagmus due to anticonvulsant toxicity.
Topics: Adult; Anticonvulsants; Carbamazepine; Eye Movements; Female; Humans; Nystagmus, Pathologic; Phenytoin; Primidone | 1978 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
[Angiokeratoma corporis diffusum (Fabry's disease). Biochemical diagnosis in plasma].
Topics: Adult; Carbamazepine; Electrocardiography; Fabry Disease; Galactosidases; Glycolipids; Heterozygote; Humans; Male; Phenytoin | 1975 |
[Fabry's diffuse angiokeratoma corporis].
Topics: Age Factors; Carbamazepine; Fabry Disease; Galactosidases; Glycolipids; Heterozygote; Humans; Kidney Failure, Chronic; Kidney Transplantation; Phenytoin; Sex Factors; Sphingolipids | 1975 |
Systematic determination of the serum phenytoin level as an aid in the management of children with epilepsy.
Topics: Acetazolamide; Adolescent; Carbamazepine; Child; Child, Preschool; Contraceptives, Oral; Drug Interactions; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Male; Phenytoin | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Acute anticonvulsant effects of diphenylhydantoin, phenobarbital, and carbamazepine: a combined electroclinical and serum level study in amygdaloid kindled cats and baboons.
Topics: Amygdala; Animals; Carbamazepine; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Haplorhini; Light; Male; Papio; Phenobarbital; Phenytoin; Seizures; Time Factors | 1976 |
Anticonvulsant drug antagonism of delta9tetrahydrocannabinol-induced seizures in rabbits.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinol; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Dronabinol; Ethosuximide; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures; Time Factors | 1977 |
The syndrome of continuous muscle fiber activity. Evidence to suggest proximal neurogenic causation.
Topics: Adolescent; Carbamazepine; Child, Preschool; Electromyography; Female; Humans; Injections, Intravenous; Male; Muscle Contraction; Muscular Diseases; Phenytoin; Posture; Syndrome | 1977 |
Painful tic convulsif.
Topics: Aged; Carbamazepine; Cerebrovascular Disorders; Female; Humans; Phenytoin; Syndrome; Tic Disorders; Trigeminal Neuralgia | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
The management of tic douloureux.
Topics: Acupuncture Therapy; Carbamazepine; Chlorphenesin; Denervation; Humans; Mephenesin; Nerve Block; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1977 |
The effect of anticonvulsant drugs which induce liver microsomal enzymes on derived and ingested phenobarbitone levels.
Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hypoxanthines; In Vitro Techniques; Inosine; Neuroblastoma; Ouabain; Phenobarbital; Phenytoin; Rats; Veratridine | 1977 |
Episodic nocturnal wanderings responsive to anticonvulsant drug therapy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Electroencephalography; Humans; Male; Phenytoin; Sleep Stages; Somnambulism; Syndrome; Wakefulness | 1977 |
Comparison of six procedures for the simultaneous determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
A rapid spectrophotometric procedure for the simultaneous micro determination of carbamazepine and 5, 5-diphenyl-hydantoin in blood.
Topics: Acridines; Carbamazepine; Humans; Indicators and Reagents; Microchemistry; Phenytoin; Spectrophotometry, Ultraviolet; Time Factors | 1976 |
[Brain stem seizures with circumscrbed elementary symptoms].
Topics: Adult; Amitriptyline; Ataxia; Brain Neoplasms; Brain Stem; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Muscles; Phenytoin | 1976 |
Plasma levels of carbamazepine and carbamazepine-10,11-epoxide during treatment of epilepsy.
Topics: Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Epoxy Compounds; Humans; Phenytoin | 1976 |
Chemical ionization mass spectrometry for rapid assay of drugs in serum.
Topics: Anticonvulsants; Barbiturates; Caffeine; Carbamazepine; Electrochemistry; Mass Spectrometry; Nicotine; Phenytoin; Primidone; Temperature; Time Factors | 1976 |
Further observations on carbamazepine plasma levels in epileptic patients. Relationships with therapeutic and side effects.
Topics: Adult; Age Factors; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1976 |
High-speed liquid chromatographic determination of antiepileptic drugs in human plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin | 1976 |
Quantitative determination of underivatized anti-convulsant drugs by high resolution gas chromatography with support-coated open tubular columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Improved method for measurement of serum levels of phenobarbital, carbamazepine, primidone and diphenylhydantoin by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Drug stimulated biotransformation of hormonal steroid contraceptives: clinical implications.
Topics: Ampicillin; Biotransformation; Carbamazepine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Enzyme Induction; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Uterine Hemorrhage | 1976 |
Chromosomal damage in epileptics on monotherapy with carbamazepine and diphenylhydantoin.
Topics: Adolescent; Adult; Carbamazepine; Chromosome Aberrations; Chromosomes; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Translocation, Genetic | 1976 |
Simultaneous gas chromatographic analysis for the four commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ion Exchange Resins; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Anticonvulsant drugs and mental symptoms: a review.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Schizophrenia | 1976 |
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Drug-Induced; Extremities; Facial Muscles; Female; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Syndrome; Tranquilizing Agents; Tremor | 1976 |
Clinical pharmacokinetics in infants and children.
Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline | 1976 |
[Automatism (author's transl)].
Topics: Automatism; Brain; Carbamazepine; Electroencephalography; Humans; Pentylenetetrazole; Phenytoin; Sclerosis | 1976 |
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione | 1975 |
Letter: Epanutin and isoniazid interaction.
Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin | 1975 |
Anticonvulsant level in saliva, serum, and cerebrospinal fluid.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
[Effects of anticonvulsive treatment on drug elimination in man. Induction of liver hydroxylating enzyme system by diphenylhydantoin and carbamazepine].
Topics: Adult; Antipyrine; Bilirubin; Carbamazepine; Creatinine; Epilepsy; Female; Half-Life; Humans; Hydroxylation; Liver; Male; Middle Aged; Phenytoin; Time Factors; Trigeminal Neuralgia | 1975 |
The management of facial pain.
Topics: Bruxism; Carbamazepine; Diagnosis, Differential; Ergotamine; Face; Female; Herpes Zoster; Humans; Male; Middle Aged; Neuralgia; Pain; Phenytoin; Temporomandibular Joint Dysfunction Syndrome; Trigeminal Neuralgia; Vascular Headaches | 1975 |
Therapeutic monitoring of anticonvulsant drugs: gas-chromatographic simultaneous determination of primidone, phenylethylmalonamide, carbamazepine, and diphenylhydantoin.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Malonates; Microchemistry; Phenylethylmalonamide; Phenytoin; Primidone | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile | 1975 |
Absorption and distribution of antiepileptic drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Capsules; Carbamazepine; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Maternal-Fetal Exchange; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Pregnancy; Suppositories; Tablets, Enteric-Coated; Time Factors | 1975 |
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Trimethadione | 1975 |
Depression of immune competence by phenytoin and carbamazepine. Studies in vivo and in vitro.
Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Antibody Formation; Carbamazepine; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Female; Humans; Hypersensitivity, Delayed; Immunoglobulin A; Immunosuppression Therapy; Lectins; Leukocyte Count; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Biosynthesis; RNA; Salmonella typhi; Sex Factors; Tetanus Toxoid | 1975 |
Hematologic toxicity of carbamazepine.
Topics: Adult; Aged; Anemia, Aplastic; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 1975 |
Psychosocial management of patients with complex partial seizures.
Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; Epilepsy, Temporal Lobe; Female; Fluphenazine; Humans; Male; Mental Disorders; Middle Aged; Neurocognitive Disorders; Patient Acceptance of Health Care; Phenobarbital; Phenytoin; Schizophrenia; Social Environment; Social Problems; Socioeconomic Factors; Syndrome | 1975 |
Paradoxical intoxication--a complication of anticonvulsant administration.
Topics: Carbamazepine; Drug Therapy, Combination; Humans; Hydantoins; Mephenytoin; Phenytoin; Seizures | 1975 |
[Poisoning with carbamazepine and diphenylhydantoin in childhood].
Topics: Adolescent; Carbamazepine; Eye Manifestations; Female; Humans; Neurologic Manifestations; Phenytoin | 1975 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
Simultaneous gas-chromatographic analysis for phenobarbital, diphenylhydantoin, carbamazepine, and primidone in serum.
Topics: Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Treatment of epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 1992 |
Microneurovascular decompression: early experiences in Srinagarind Hospital.
Topics: Carbamazepine; Diazepam; Facial Paralysis; Female; Humans; Male; Microsurgery; Middle Aged; Phenytoin; Trigeminal Neuralgia | 1992 |
Cognitive functions, epileptic syndromes and antiepileptic drugs.
Topics: Adolescent; Adult; Carbamazepine; Child; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1992 |
Interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations.
Topics: Adult; Aged; Antifungal Agents; Azoles; Carbamazepine; Coccidioides; Cryptococcus neoformans; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Male; Middle Aged; Mycoses; Phenytoin; Rifampin | 1992 |
Salivary concentrations of antiepileptic drugs, oestradiol and progesterone throughout pregnancy in epileptic women.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Osmolar Concentration; Phenytoin; Pregnancy; Pregnancy Complications; Progesterone; Saliva | 1992 |
What to do when the first anticonvulsant does not work.
Topics: Aminocaproates; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Phenytoin; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1992 |
Therapeutic drug monitoring improves seizure control and reduces anticonvulsant side-effects in patients with refractory epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Monitoring; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Follow-Up Studies; Humans; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Anticonvulsants inhibit rat neuronal somatostatin release.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hypothalamus; In Vitro Techniques; Kinetics; Male; Neurons; Ouabain; Phenytoin; Radioimmunoassay; Rats; Rats, Inbred Strains; Somatostatin | 1992 |
Comparative effects of carbamazepine, phenytoin, diazepam and clonazepam on inhibitory avoidance learning in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Clonazepam; Diazepam; Male; Mice; Phenytoin; Reaction Time | 1992 |
Anticonvulsant activity of carbamazepine and diphenylhydantoin against maximal electroshock in mice chronically treated with aminophylline.
Topics: Aminophylline; Animals; Anticonvulsants; Carbamazepine; Electroshock; Male; Mice; Phenytoin; Seizures; Theophylline | 1992 |
1,3-Di(2-[5-3H]tolyl)guanidine labels more than one site in rat forebrain.
Topics: Animals; Binding Sites; Binding, Competitive; Carbamazepine; Guanidines; Haloperidol; Male; Pentazocine; Phenytoin; Piperidines; Prosencephalon; Rats; Rats, Wistar; Receptors, sigma; Stereoisomerism | 1992 |
[Preparation of phenyl treated packing materials for high-performance liquid chromatography: evaluation by retention behaviour of carbamazepine and diphenylhydantoin].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Phenytoin; Silanes | 1992 |
Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases.
Topics: Adolescent; Adult; Angiography; Brain Neoplasms; Carbamazepine; Cerebral Hemorrhage; Child; Epilepsy; Female; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 1992 |
"An analysis of epileptic patients nonresponsive to drugs".
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Treatment Failure | 1992 |
Cognitive effects of antiepileptic drug discontinuation.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 1992 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonazepam; Disease Susceptibility; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1992 |
Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid | 1992 |
Effects of four common anticonvulsants on the high pressure nervous syndrome in the rat.
Topics: Animals; Carbamazepine; Diazepam; Drug Evaluation, Preclinical; High Pressure Neurological Syndrome; Male; Phenobarbital; Phenytoin; Premedication; Rats; Rats, Inbred Strains | 1992 |
Phenytoin and carbamazepine decreased oral bioavailability of praziquantel.
Topics: Adult; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Praziquantel | 1992 |
Segregation of the growth slowing effects of valproic acid from phenytoin and carbamazepine on lymphoid tumor cells.
Topics: Carbamazepine; Cell Division; Culture Techniques; Humans; Kinetics; Leukemia; Lymphoma; Phenytoin; Regression Analysis; Valproic Acid | 1992 |
The effect of anticonvulsants on cognitive functioning following a probable encephalitic illness.
Topics: Carbamazepine; Drug Therapy, Combination; Electroencephalography; Encephalitis; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Male; Mental Recall; Middle Aged; Neurocognitive Disorders; Neuropsychological Tests; Phenytoin; Sulpiride | 1992 |
Antiepileptic drug disposition during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1992 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
Clinical utility of unbound antiepileptic drug blood levels in the management of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Valproic Acid | 1992 |
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Female; Hair; Humans; Long-Term Care; Magnesium; Male; Middle Aged; Phenobarbital; Phenytoin; Schizophrenia; Valproic Acid; Zinc | 1992 |
A micro-enzyme-multiplied immunoassay technique plate assay for antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Female; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; NAD; Phenytoin; Valproic Acid | 1992 |
Course of pregnancy and fetal outcome following maternal exposure to carbamazepine and phenytoin: a prospective study.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Carbamazepine; Epilepsy; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies | 1992 |
Automated homogeneous liposome immunoassay systems for anticonvulsant drugs.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Fluorescence Polarization Immunoassay; Glucosephosphate Dehydrogenase; Humans; Immunoassay; Immunoenzyme Techniques; Liposomes; Phenobarbital; Phenytoin; Quality Control; Spectrophotometry | 1992 |
Toxic effects of antiepileptic drugs on immunoglobulin gene expression.
Topics: Animals; Carbamazepine; Gene Expression; Genes, Immunoglobulin; Mice; Phenytoin; RNA, Messenger; Tumor Cells, Cultured | 1992 |
Anticonvulsant-induced chronic pancreatitis. A case report.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Cytochrome P-450 Enzyme System; Epilepsy; Free Radicals; Humans; Male; Pancreatitis; Phenytoin; Valproic Acid | 1992 |
A nineteen-year-old man with altered mental status.
Topics: Acetazolamide; Adult; Carbamazepine; Diagnosis, Differential; Drug Interactions; Electroencephalography; Epilepsy, Absence; Epilepsy, Complex Partial; Humans; Hyperventilation; Male; Phenytoin | 1992 |
Muscle cramp as a feature of neuromuscular disease. Five neuromuscular disorders, accompanied by frequent muscle cramps.
Topics: Adult; Algorithms; Carbamazepine; Fasciculation; Female; Humans; Male; Middle Aged; Motor Neuron Disease; Muscle Cramp; Neuromuscular Diseases; Phenytoin | 1992 |
Antiepileptic drug-induced lymphoproliferative disorder associated with acquired C1 esterase inhibitor deficiency and angioedema.
Topics: Aged; Angioedema; Carbamazepine; Complement C1 Inactivator Proteins; Female; Humans; Leukemia, B-Cell; Lymphoproliferative Disorders; Phenytoin | 1992 |
Metabolism of carbamazepine: evidence of autoinduction in Chinese.
Topics: Adult; Asian People; Carbamazepine; Half-Life; Humans; Male; Phenytoin; Taiwan | 1991 |
Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats.
Topics: Animals; Carbamazepine; Drug Resistance; Electrodes; Epilepsy; Female; Kindling, Neurologic; Phenytoin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Action of diazepam on the voltage-dependent Na+ current. Comparison with the effects of phenytoin, carbamazepine, lidocaine and flumazenil.
Topics: Action Potentials; Animals; Carbamazepine; Cell Line; Cells, Cultured; Diazepam; Embryo, Mammalian; Flumazenil; Kinetics; Lidocaine; Mice; Neuroblastoma; Neurons; Phenytoin; Sodium Channels; Spinal Cord | 1991 |
Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro.
Topics: Action Potentials; Animals; Anticonvulsants; Batrachotoxins; Carbamazepine; Cells, Cultured; Electrophysiology; Epilepsy; Kinetics; Mice; Neurons; Phenylurea Compounds; Phenytoin; Radioligand Assay; Sodium Channels; Spinal Cord; Synaptosomes; Thiazoles | 1991 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Carbamazepine and phenytoin inhibit somatostatin release from dispersed cerebral cells in culture.
Topics: Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Colforsin; Phenytoin; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Purinergic; Sodium Channels; Somatostatin | 1991 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
Acute effects of anticonvulsants on brain-stem auditory evoked potentials in rats.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain Stem; Carbamazepine; Evoked Potentials, Auditory; Male; Phenytoin; Rats; Rats, Inbred Strains; Reaction Time | 1990 |
Vagal stimulation for control of complex partial seizures in medically refractory epileptic patients.
Topics: Adult; Carbamazepine; Cybernetics; Electric Stimulation Therapy; Electrocardiography; Electrocardiography, Ambulatory; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Equipment Design; Evoked Potentials; Female; Gastric Acid; Humans; Male; Middle Aged; Phenytoin; Prostheses and Implants; Vagus Nerve | 1991 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male; Parkinson Disease; Phenobarbital; Phenytoin; Postural Balance; Reaction Time; Time Factors; Vagus Nerve; Valproic Acid | 1991 |
The investigation of antiepileptic action of qingyangshen (QYS)--effect of QYS on the concentrations of neuropeptides in rat brain.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Drugs, Chinese Herbal; Male; Neuropeptides; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Somatostatin; Substance P | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Female; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Pregnancy; Spinal Cord | 1990 |
Familial occurrence of hypersensitivity to phenytoin.
Topics: Adult; Animals; Carbamazepine; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; Mice; Phenobarbital; Phenytoin | 1991 |
Carbamazepine-hypersensitivity: assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cell Death; Drug Hypersensitivity; Female; Humans; Male; Microsomes, Liver; Middle Aged; Oxcarbazepine; Phenytoin | 1991 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
Clinical evaluation of five therapeutic drugs using dry film multilayer technology on the OPUS immunoassay system.
Topics: Carbamazepine; Evaluation Studies as Topic; Humans; Immunoassay; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Reference Standards; Sensitivity and Specificity; Theophylline; Valproic Acid | 1991 |
[Evaluation of the effectiveness of monotherapy in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Evaluation; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Mycosis fungoides-like lesions associated with phenytoin and carbamazepine therapy.
Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Diagnosis, Differential; Drug Eruptions; Epilepsy; Female; Humans; Male; Mycosis Fungoides; Phenytoin; Skin Neoplasms; T-Lymphocytes | 1991 |
Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome.
Topics: Adult; Carbamazepine; Cross Reactions; Drug Eruptions; Facial Dermatoses; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Pruritus; Scalp Dermatoses; Skin Diseases, Vesiculobullous; Syndrome; Urticaria | 1991 |
Neuromyotonia in hereditary motor neuropathy.
Topics: Adolescent; Anti-Arrhythmia Agents; Carbamazepine; Child; Electromyography; Female; Humans; Lidocaine; Male; Muscles; Myotonia Congenita; Myotonic Dystrophy; Neural Conduction; Neuromuscular Diseases; Pedigree; Peripheral Nerves; Peripheral Nervous System Diseases; Phenytoin; Tocainide | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Isoantigens; Liver; Liver Diseases; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1991 |
Comparison of gabapentin with other antiepileptic and GABAergic drugs.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Carbamazepine; Cats; Cyclohexanecarboxylic Acids; Electric Stimulation; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Injections, Intravenous; Maxillary Nerve; Phenytoin; Reaction Time; Trigeminal Nuclei | 1991 |
Plasma uric acid in patients receiving anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Prospective Studies; Uric Acid; Valproic Acid | 1991 |
Short-term effects of administration of anticonvulsant drugs on free carnitine and acylcarnitine in mouse serum and tissues.
Topics: Animals; Anticonvulsants; Carbamazepine; Carnitine; Heart; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Phenobarbital; Phenytoin; Prohibitins; Valproic Acid | 1991 |
Sleep spindles in epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenytoin; Sleep | 1991 |
Alteration of renal carnitine metabolism by anticonvulsant treatment.
Topics: Ammonia; Animals; Anticonvulsants; Carbamazepine; Carnitine; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Labor, Obstetric; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Valproic Acid | 1991 |
Clinical implications of seizures in neurosarcoidosis.
Topics: Adolescent; Adult; Brain Diseases; Carbamazepine; Female; Humans; Male; Middle Aged; Nervous System Diseases; Phenytoin; Prednisone; Sarcoidosis; Seizures | 1991 |
Captopril as adjunctive treatment in catamenial epilepsy.
Topics: Adult; Captopril; Carbamazepine; Drug Administration Schedule; Epilepsy, Tonic-Clonic; Female; Humans; Menstrual Cycle; Phenytoin | 1991 |
Effect of serum separator tubes on free and total phenytoin and carbamazepine serum concentrations.
Topics: Blood Component Removal; Blood Specimen Collection; Carbamazepine; Cell Separation; Centrifugation; Gels; Humans; Phenytoin | 1991 |
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children.
Topics: Analysis of Variance; Carbamazepine; Carnitine; Child; Drug Combinations; Fatty Acids; Fatty Acids, Volatile; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1991 |
Epileptic patients refractory to drug therapy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin G; Immunoglobulins; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Measurement of phenytoin and carbamazepine in an ultrafiltrate of saliva.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Phenytoin; Saliva; Specimen Handling | 1991 |
Synthesis of mixed-functional-phase silica supports for liquid chromatography and their applications to assays of drugs in serum.
Topics: Carbamazepine; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Silicon Dioxide | 1990 |
Effects of anticonvulsants and gamma-aminobutyric acid (GABA)-mimetic drugs on immunoreactive somatostatin and GABA contents in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, Gel; Drug Interactions; Ethanolamines; gamma-Aminobutyric Acid; Male; Muscimol; Phenytoin; Rats; Rats, Inbred Strains; Somatostatin; Valproic Acid | 1990 |
Antiepileptic drugs in the treatment of neuroleptic-induced supersensitivity psychosis.
Topics: Adult; Antipsychotic Agents; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Psychoses, Substance-Induced; Schizophrenia | 1990 |
Neuropsychological effects of carbamazepine and phenytoin: a reanalysis.
Topics: Carbamazepine; Humans; Neuropsychological Tests; Phenytoin; Psychotropic Drugs; Wechsler Scales | 1991 |
Methsuximide for intractable childhood seizures.
Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Phenytoin; Succinimides | 1991 |
An ultrafiltrate of saliva collected in situ as a biological sample for diagnostic evaluation.
Topics: Carbamazepine; Humans; Phenobarbital; Phenytoin; Saliva; Specimen Handling; Ultrafiltration | 1991 |
Seizures: introduction and commentary.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper.
Topics: Carbamazepine; Craniotomy; Epilepsy; Humans; Phenytoin; Postoperative Complications; Retrospective Studies; Risk Factors; Time Factors | 1991 |
Interactions between calcium channel blockers and the anticonvulsants carbamazepine and phenytoin.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Carbamazepine; Diltiazem; Drug Interactions; Female; Humans; Male; Middle Aged; Nifedipine; Phenytoin; Retrospective Studies; Seizures; Verapamil | 1991 |
Encephalomyelopathy as an idiosyncratic reaction to carbamazepine: a case report.
Topics: Aged; Carbamazepine; Encephalomyelitis; Female; Humans; Phenytoin; Trigeminal Neuralgia | 1991 |
[Bradyarrhythmias induced by antiepileptics increase frequency of epileptic seizures].
Topics: Aged; Bradycardia; Carbamazepine; Epilepsy; Humans; Male; Phenytoin | 1991 |
Intraindividual variability of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Adult; Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Male; Phenobarbital; Phenytoin; Saliva | 1991 |
Comparison of enzyme immunoassay and fluorescence polarization immunoassay as techniques for measuring anticonvulsant drugs on the same analytical instrument.
Topics: Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1991 |
Simultaneous separation and determination (in serum) of phenytoin and carbamazepine and their deuterated analogues by high-performance liquid chromatography--ultraviolet detection for tracer studies.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Humans; Phenytoin; Ultraviolet Rays | 1990 |
The effects of phenytoin and carbamazepine on serum concentrations of mono-unsaturated metabolites of valproic acid.
Topics: Adult; Aged; Biotransformation; Carbamazepine; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1990 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Functional Laterality; Humans; Male; Phenytoin; Seizures; Sex Factors; Valproic Acid | 1990 |
In vivo determination of valproate binding constants during sole and multi-drug therapy.
Topics: Binding, Competitive; Carbamazepine; Drug Therapy, Combination; Food; Humans; Phenytoin; Seizures; Valproic Acid | 1990 |
[Clinical use of pharmacologic monitoring at a hospital community].
Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Utilization; Humans; Phenobarbital; Phenytoin; Product Surveillance, Postmarketing; Spain; Theophylline; Valproic Acid | 1990 |
Anticonvulsant therapy increases fentanyl requirements during anaesthesia for craniotomy.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Anticonvulsants; Carbamazepine; Craniotomy; Drug Interactions; Epilepsy; Fentanyl; Humans; Middle Aged; Phenytoin; Primidone; Valproic Acid | 1990 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
The inhibitory effect of anticonvulsants on human sperm motility: measured with a trans-membrane migration method.
Topics: Adult; Anticonvulsants; Carbamazepine; Cell Membrane; Depression, Chemical; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sperm Motility; Valproic Acid | 1990 |
Possible roles for frequent salivary antiepileptic drug monitoring in the management of epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Menstruation; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Saliva | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Effects of polytherapy with phenytoin, carbamazepine, and stiripentol on formation of 4-ene-valproate, a hepatotoxic metabolite of valproic acid.
Topics: Adult; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Drug Interactions; Enzyme Activation; Fatty Acids, Monounsaturated; Female; Humans; Liver; Male; Phenytoin; Valproic Acid | 1990 |
[High-dose monotherapy in intractable epilepsy].
Topics: Adolescent; Adult; Carbamazepine; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 1990 |
The interaction of phenytoin and carbamazepine with combined oral contraceptive steroids.
Topics: Adolescent; Adult; Carbamazepine; Contraceptive Agents, Female; Contraceptives, Oral, Combined; Drug Interactions; Ethinyl Estradiol; Female; Humans; Levonorgestrel; Norgestrel; Phenytoin | 1990 |
Development of posttraumatic epilepsy.
Topics: Adolescent; Adult; Aged; Alcoholism; Atrophy; Brain Injuries; Carbamazepine; Cerebral Cortex; Cerebral Hemorrhage; Epilepsy, Post-Traumatic; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Postoperative Complications; Prospective Studies; Risk Factors | 1990 |
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Neurologic Examination; Panic Disorder; Phenobarbital; Phenytoin | 1990 |
Treatment of epilepsy in people with multiple handicap.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Disabled Persons; Epilepsy; Humans; Phenytoin; Valproic Acid | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
Direct serum injection high-performance liquid chromatographic method for the simultaneous determination of phenobarbital, carbamazepine and phenytoin.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
A simple and disposable visual measuring device to assay antiepileptic drugs from whole blood samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
Comparison of human, bovine, and newborn calf serum in the preparation of external quality assurance samples for therapeutic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Immunoenzyme Techniques; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Quality Control; Radioimmunoassay; Theophylline | 1990 |
Dichotic listening and complex partial seizures.
Topics: Adult; Aged; Carbamazepine; Cerebral Cortex; Dichotic Listening Tests; Dominance, Cerebral; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Speech Perception | 1990 |
Pre-trigeminal neuralgia.
Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Diagnosis, Differential; Female; Humans; Jaw; Joint Diseases; Male; Middle Aged; Pain; Phenytoin; Trigeminal Neuralgia | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Selective response to carbamazepine in a case of organic mood disorder.
Topics: Aged; Carbamazepine; Depressive Disorder; Female; Humans; Neurocognitive Disorders; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Acne keloidalis-like lesions on the scalp associated with antiepileptic drugs.
Topics: Acne Keloid; Adult; Carbamazepine; Epilepsy; Humans; Male; Phenytoin; Scalp Dermatoses | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
Dose dependent enzyme induction by oxcarbazepine?
Topics: Aged; Anticonvulsants; Antipyrine; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Liver; Male; Middle Aged; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia | 1990 |
Effects of age and antiepileptic drugs on plasma levels and kinetics of clobazam and N-desmethylclobazam.
Topics: Adolescent; Adult; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clobazam; Drug Therapy, Combination; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1990 |
[Treatment of neuralgiform maxillofacial pain with hydantoin (Phenhydan)].
Topics: Adult; Aged; Carbamazepine; Drug Combinations; Facial Neuralgia; Female; Humans; Hydantoins; Male; Middle Aged; Phenytoin | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Cognitive function in adult epileptic patients established on anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Female; Humans; Intelligence; Male; Middle Aged; Osmolar Concentration; Phenytoin; Psychomotor Performance; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--carbamazepine.
Topics: Aging; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid.
Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Sex Factors; Valproic Acid | 1990 |
Temperature effects on the estimation of free levels of phenytoin carbamazepine and phenobarbitone.
Topics: Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Protein Binding; Temperature | 1990 |
Evaluation of the Ames Seralyzer for the determination of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Saliva | 1990 |
Protein binding of antiepileptic drugs during pregnancy, labor, and puerperium.
Topics: Adult; Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Female; Fetal Blood; Humans; Labor, Obstetric; Orosomucoid; Phenytoin; Postpartum Period; Pregnancy; Protein Binding; Seizures; Serum Albumin | 1990 |
Simultaneous assay of felbamate plus carbamazepine, phenytoin, and their metabolites by liquid chromatography with mobile phase optimization.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenylcarbamates; Phenytoin; Propylene Glycols | 1990 |
Bradycardia and syncope as manifestations of partial epilepsy.
Topics: Adult; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Pacemaker, Artificial; Phenytoin; Syncope | 1990 |
Phenobarbital hepatotoxicity in an 8-month-old infant.
Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; Male; Methylprednisolone; Phenobarbital; Phenytoin | 1990 |
Effects of anticonvulsants on hippocampus-generating seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; Hippocampus; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Seizures | 1990 |
Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Period | 1990 |
Serum protein binding of antiepileptic drugs in Sri Lankans.
Topics: Adolescent; Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Sri Lanka | 1990 |
Head circumference in children of epileptic mothers: contributions of drug exposure and genetic background.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy; Female; Humans; Intelligence Tests; Male; Microcephaly; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects | 1990 |
Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Epilepsy; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1990 |
Anticonvulsant drug mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Clonazepam; Electroshock; gamma-Aminobutyric Acid; Humans; Ion Channels; Membrane Potentials; Mice; Neurons; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Evoked metabolic responses in the limbic-striate system produced by stimulation of anterior thalamic nucleus in man.
Topics: Adult; Brain; Carbamazepine; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Female; Glucose; Humans; Hydrocortisone; Limbic System; Male; Phenytoin; Radionuclide Imaging; Thalamic Nuclei; Valproic Acid | 1987 |
Site of anticonvulsant action on sodium channels: autoradiographic and electrophysiological studies in rat brain.
Topics: Aconitine; Animals; Autoradiography; Batrachotoxins; Brain; Carbamazepine; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Ion Channels; Male; Neurons; Phenytoin; Rats; Receptors, Cholinergic; Sodium; Sodium Channels; Tritium; Veratridine | 1987 |
The effect of repeated seizures on anticonvulsant drug response in the kindling model.
Topics: Animals; Brain; Carbamazepine; Kindling, Neurologic; Male; Membrane Potentials; Phenobarbital; Phenytoin; Rats; Seizures | 1987 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Humans; Phenytoin; Valproic Acid | 1989 |
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid.
Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Carnitine deficiency associated with anticonvulsant therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1989 |
Effect of phenytoin, carbamazepine, and valproic acid on caffeine metabolism.
Topics: Adolescent; Adult; Aged; Antipyrine; Caffeine; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy; Female; Half-Life; Humans; Hydrocortisone; Male; Middle Aged; Phenytoin; Valproic Acid | 1989 |
Thyroid hormone concentrations in epileptic patients.
Topics: Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Humans; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1989 |
Variations in protein binding of drugs in plasma and serum.
Topics: Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Fluoroimmunoassay; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Protein Binding; Theophylline; Valproic Acid | 1989 |
Cost-effective assays for use in monitoring carbamazepine, phenobarbital, and phenytoin in serum.
Topics: Carbamazepine; Chromatography, Gas; Cost-Benefit Analysis; Fluoroimmunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reference Standards | 1989 |
Effects of anticonvulsants on plasma levels and entero-hepatic circulation of valproic acid and on hepatic drug metabolizing enzyme activities in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Enterohepatic Circulation; Liver; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Inbred Strains; Valproic Acid | 1989 |
Probable pseudocholinesterase induction by valproic acid, carbamazepine and phenytoin leading to increased serum aspirin-esterase activity in epileptics.
Topics: Adolescent; Adult; Analysis of Variance; Carbamazepine; Carboxylic Ester Hydrolases; Cholinesterases; Enzyme Induction; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1989 |
An atypical hypersensitivity reaction.
Topics: Adolescent; Carbamazepine; Drug Eruptions; Glomerulonephritis; Humans; Liver; Liver Function Tests; Male; Phenytoin; Seizures | 1989 |
Evidence for a common site of action of lidocaine and carbamazepine in voltage-dependent sodium channels.
Topics: Animals; Batrachotoxins; Carbamazepine; Female; Hippocampus; In Vitro Techniques; Lidocaine; Male; Phenytoin; Rats; Rats, Inbred Strains; Sodium Channels | 1989 |
Inhibition of agonist-stimulated inositol lipid metabolism by the anticonvulsant carbamazepine in rat hippocampus.
Topics: Animals; Carbachol; Carbamazepine; Hippocampus; Histamine; In Vitro Techniques; Inositol; Lipid Metabolism; Male; Phenytoin; Rats; Rats, Inbred Strains; Sodium Channels; Tetrodotoxin; Veratrine | 1989 |
Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture.
Topics: Animals; Anticonvulsants; Carbamazepine; Cell Survival; Cells, Cultured; Dendrites; Diazepam; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Phenytoin; Rats | 1989 |
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1985 |
Voltage clamp analysis of the inhibitory actions of diphenylhydantoin and carbamazepine on voltage-sensitive sodium channels in neuroblastoma cells.
Topics: Animals; Carbamazepine; Cells, Cultured; Electric Stimulation; Ion Channels; Mice; Neuroblastoma; Phenytoin; Sodium | 1985 |
Structural requirements for bioactivation of anticonvulsants to cytotoxic metabolites in vitro.
Topics: Animals; Anticonvulsants; Biotransformation; Carbamazepine; Cell Survival; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Leukocytes; Male; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenytoin; Urea | 1989 |
Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Saliva; Spectrophotometry, Ultraviolet | 1989 |
Dosing accuracy of antiepileptic drug regimens as determined by serum concentrations in outpatient epilepsy clinic patients.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Outpatients; Phenobarbital; Phenytoin | 1989 |
[Pharmacotherapy of trigeminal neuralgia].
Topics: Amphetamines; Baclofen; Carbamazepine; Female; Humans; Imipramine; Male; Phenytoin; Trigeminal Neuralgia | 1989 |
Daily salivary anticonvulsant monitoring in patients with intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Saliva | 1989 |
A micromethod for the estimation of free levels of anticonvulsant drugs in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Microchemistry; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Ultrafiltration | 1989 |
Barbiturate-related connective tissue disorders.
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Connective Tissue Diseases; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1989 |
Phenytoin-carbamazepine cross-sensitivity.
Topics: Adult; Blood Cell Count; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Female; Humans; Liver Function Tests; Phenytoin | 1989 |
Saliva monitoring of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1989 |
Phenytoin withdrawal and seizure frequency.
Topics: Adult; Carbamazepine; Diazepam; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenytoin; Substance Withdrawal Syndrome | 1989 |
Pregnancy and epilepsy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Estrogens; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Progesterone; Prospective Studies | 1989 |
The effect of anticonvulsants on the dexamethasone suppression test.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Dexamethasone; Epilepsy; Humans; Hydrocortisone; Phenobarbital; Phenytoin | 1989 |
Effect of aminophylline upon the protective activity of common antiepileptic drugs and their plasma levels in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Male; Mice; Phenobarbital; Phenytoin; Seizures | 1989 |
Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Injections; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1989 |
Effects of phenytoin, carbamazepine, and clonazepam on cortex- and amygdala-evoked potentials in partially kindled rats.
Topics: Amygdala; Animals; Carbamazepine; Cerebral Cortex; Clonazepam; Electric Stimulation; Evoked Potentials; Kindling, Neurologic; Male; Phenytoin; Rats; Synapses | 1989 |
Trigeminal neuralgia.
Topics: Adult; Anesthesia, General; Baclofen; Carbamazepine; Chlorphenesin; Female; Hematologic Tests; Humans; Phenytoin; Physical Examination; Preanesthetic Medication; Trigeminal Neuralgia | 1989 |
[Mechanism of action of antiepileptic drugs].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; gamma-Aminobutyric Acid; Ion Exchange; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Synaptic Transmission; Valproic Acid | 1987 |
Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites.
Topics: Acetonitriles; Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Perchlorates; Phenobarbital; Phenytoin; Quality Control; Regression Analysis; Statistics as Topic; Trichloroacetic Acid; Valproic Acid | 1988 |
Differential effects of anticonvulsants on developing neurons in vitro.
Topics: Animals; Anticonvulsants; Binding, Competitive; Carbamazepine; Cells, Cultured; Chick Embryo; Immunohistochemistry; Neurons; Phenobarbital; Phenytoin; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Valproic Acid | 1988 |
Antiepileptic drugs and cerebral glucose metabolism.
Topics: Anticonvulsants; Brain; Carbamazepine; gamma-Aminobutyric Acid; Glucose; Humans; Phenobarbital; Phenytoin; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
Serum 5'-nucleotidase in patients receiving anti-epileptic drugs.
Topics: 5'-Nucleotidase; Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Nucleotidases; Phenobarbital; Phenytoin; Sex Factors | 1985 |
Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Central Nervous System; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Mice; Neurons; Phenytoin; Sodium; Spinal Cord | 1986 |
Comparison of fluorescence polarization immunoassay and high performance liquid chromatography for the quantitative determination of phenytoin, phenobarbitone and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Phenobarbital; Phenytoin; Quality Control | 1986 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
Relationship between ossification and body weight of the CD-1 mouse fetus exposed in utero to anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Female; Fetus; Mice; Osteogenesis; Phenytoin; Pregnancy; Teratogens; Valproic Acid | 1986 |
The influence of long-term anticonvulsant therapy with diphenylhydantoin and carbamazepine on serum gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver Function Tests; Male; Middle Aged; Phenytoin | 1988 |
[Altered gamma-glutamyltransferase, aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase serum activities in long-term anticonvulsive therapy--comparison of diphenylhydantoin and carbamazepine].
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Male; Phenytoin; Sex Factors | 1988 |
The effect of phenytoin and carbamazepine on serum dehydroepiandrosterone sulfate in men and women who have partial seizures with temporal lobe involvement.
Topics: Adolescent; Adult; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenytoin | 1986 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
Quantitative vibration perception thresholds in patients under prolonged antiepileptic treatment.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Female; Humans; Hypesthesia; Male; Middle Aged; Peripheral Nervous System Diseases; Phenytoin; Sensory Thresholds; Vibration | 1985 |
Activation of platelet function in Fabry's disease.
Topics: Adolescent; Adult; alpha-Galactosidase; Carbamazepine; Child; Fabry Disease; Female; Heterozygote; Humans; Leukocytes; Male; Middle Aged; Phenytoin; Platelet Aggregation; Platelet Count | 1986 |
Impact of a pharmacokinetics consultation service on clinical outcomes in an ambulatory-care epilepsy clinic.
Topics: Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Outpatient Clinics, Hospital; Pharmacology, Clinical; Pharmacy Service, Hospital; Phenytoin; Referral and Consultation; Victoria | 1988 |
[The correlation between concentrations of anticonvulsive drugs in the brain and various parameters of maximal electroshock seizures in mice].
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1986 |
Carbamazepine, phenytoin and sodium valproate monotherapy.
Topics: Carbamazepine; Epilepsy; Humans; Phenytoin; Valproic Acid | 1986 |
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin | 1986 |
Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electric Stimulation; Ethosuximide; gamma-Aminobutyric Acid; Magnesium; Mice; Neurons; Phenytoin; Seizures; Sodium; Spinal Cord; Valproic Acid | 1986 |
The influence of seizure type and medication on psychiatric symptoms in epileptic patients.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Irritable Mood; Male; Phenytoin; Sleep Wake Disorders; Social Class | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Epilepsy; Humans; Phenytoin; Status Epilepticus; Valproic Acid | 1986 |
A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in out-patients with epilepsy.
Topics: Adult; Calcium; Carbamazepine; Diet; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Ultraviolet Rays; Valproic Acid; Vitamin D | 1986 |
[Various matters concerning the improvement of therapeutic tactics in epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mental Disorders; Middle Aged; Phenytoin; Psychotropic Drugs; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Memory disturbances in epileptic patients.
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Memory Disorders; Phenytoin; Valproic Acid | 1986 |
Synergistic effects of oxiracetam and piracetam in combination with antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Drug Synergism; Drug Therapy, Combination; Epilepsy; Male; Phenobarbital; Phenytoin; Piracetam; Pyrrolidines; Pyrrolidinones; Rats; Valproic Acid | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Oxadiazoles; Phenobarbital; Phenytoin; Quisqualic Acid; Seizures; Valproic Acid | 1986 |
Long-term anticonvulsant therapy and vitamin D metabolism in ambulatory pubertal children.
Topics: Adolescent; Anticonvulsants; Calcifediol; Calcitriol; Calcium; Carbamazepine; Child; Drug Therapy, Combination; Female; Humans; Male; Phenytoin; Rickets; Seasons; Valproic Acid | 1986 |
Barbiturate-refractory epilepsy: safe schedule for therapeutic substitution.
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Carbamazepine; Drug Tolerance; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Valproic Acid | 1986 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Growth Retardation; France; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Italy; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Sweden; Valproic Acid | 1987 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; Humans; Memory Disorders; Phenobarbital; Phenytoin; Temporal Lobe; Valproic Acid | 1987 |
Anticonvulsant medication in a mental handicap hospital: 1972-1982.
Topics: Anticonvulsants; Carbamazepine; Female; Hospitals, Psychiatric; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
[Rolandi epilepsy--a frequent seizure disorder in childhood. Symptomatology, electroencephalography, etiology, therapy, prognosis].
Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Evoked Potentials; Female; Humans; Learning Disabilities; Male; Neurocognitive Disorders; Phenytoin; Prognosis; Recurrence; Sleep Stages | 1988 |
An interaction between cytostatic and anticonvulsant drugs.
Topics: Adenocarcinoma, Papillary; Adult; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carbamazepine; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Interactions; Epilepsy; Female; Humans; Ovarian Neoplasms; Phenytoin; Valproic Acid | 1988 |
The effective evaluation of thyroid status in patients on phenytoin, carbamazepine or sodium valproate attending an epilepsy clinic.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Valproic Acid | 1987 |
Anticonvulsant-induced marrow suppression and immune thrombocytopenia.
Topics: Antigen-Antibody Complex; Blood Platelets; Bone Marrow; Carbamazepine; Cells, Cultured; Female; Granulocytes; Humans; Immunoglobulin G; Middle Aged; Phenytoin; Thrombocytopenia | 1988 |
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid | 1988 |
A comparative study of the relative effects of anticonvulsant drugs and dietary folate on the red cell folate status of patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diet; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenytoin; Valproic Acid | 1987 |
[Pharmacokinetic results of some antiepileptics].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1988 |
Antiepileptic drugs reduce serum uric acid.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Male; Phenytoin; Sex Factors; Uric Acid; Valproic Acid | 1987 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Prospective Studies; Ultrasonography; Valproic Acid | 1988 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Variability of phenytoin, carbamazepine and valproate concentrations in a clinic population.
Topics: Carbamazepine; Epilepsy; Female; Humans; Male; Minnesota; Outpatient Clinics, Hospital; Patient Compliance; Phenytoin; Valproic Acid | 1988 |
[Clinical treatment of resistant epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenytoin; Prognosis; Valproic Acid | 1988 |
Changes in clearance of sodium valproate with changes in dose.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1987 |
Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Drug Evaluation, Preclinical; Drug Hypersensitivity; Female; Humans; Inactivation, Metabolic; Infant; Lymphocytes; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Risk | 1988 |
Role of human serum biotinidase as biotin-binding protein.
Topics: Amidohydrolases; Binding Sites; Biotin; Biotinidase; Bromosuccinimide; Carbamazepine; Carrier Proteins; Centrifugation, Density Gradient; Chloromercuribenzoates; Chromatography, Gel; Globulins; Humans; Hydrogen-Ion Concentration; p-Chloromercuribenzoic Acid; Phenobarbital; Phenytoin; Serum Albumin | 1988 |
A paroxysmal ocular motility disorder in multiple sclerosis.
Topics: Adult; Carbamazepine; Diagnosis, Differential; Eye Movements; Female; Humans; Multiple Sclerosis; Ophthalmoplegia; Phenytoin; Pyramidal Tracts; Spinal Cord Diseases | 1988 |
Relevance of poor compliance for seizure control.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Middle Aged; Patient Compliance; Phenytoin; Primidone; Recurrence; Sleep Deprivation | 1988 |
Effects of drugs on aminophylline elimination in rats.
Topics: Aminophylline; Animals; Behavior, Animal; Carbamazepine; Cimetidine; Drug Combinations; Drug Interactions; Erythromycin; Female; Half-Life; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Phenytoin and carbamazepine.
Topics: Carbamazepine; Humans; Phenytoin | 1988 |
Anticonvulsant-induced liver damage.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Clonazepam; Humans; Liver; Liver Diseases; Male; Phenytoin | 1988 |
Episodic nocturnal wanderings in non-epileptic young patients.
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Female; Humans; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Somnambulism | 1988 |
Carbamazepine increases phenytoin serum concentration and reduces phenytoin clearance.
Topics: Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Male; Middle Aged; Phenytoin; Time Factors | 1988 |
Carbamazepine and phenytoin. Comparison of cognitive effects in epileptic patients during monotherapy and withdrawal.
Topics: Carbamazepine; Cognition; Epilepsy; Humans; Intelligence Tests; Neuropsychological Tests; Phenytoin | 1988 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
Effects of anticonvulsants on responses to excitatory amino acids applied topically to rat cerebral cortex.
Topics: Administration, Topical; Amino Acids; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Chlormethiazole; Diazepam; Evoked Potentials, Somatosensory; Injections, Intraperitoneal; Male; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1988 |
Audiogenic seizures in Wistar rats before and after repeated auditory stimuli: clinical, pharmacological, and electroencephalographic studies.
Topics: Acoustic Stimulation; Animals; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Female; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1988 |
[Loading-doses of carbamazepine and diphenylhydantoin: use in high-risk patients].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Humans; Middle Aged; Phenytoin; Risk | 1987 |
[Cursive and gelastic manifestations of epilepsies].
Topics: Adolescent; Adult; Carbamazepine; Child; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Female; Humans; Laughter; Male; Phenytoin; Running; Stereotyped Behavior; Tomography, X-Ray Computed | 1987 |
Simultaneous measurement of phenobarbital, carbamazepine, phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy.
Topics: Aged; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Dual effects of carbamazepine-phenytoin interaction.
Topics: Adolescent; Adult; Carbamazepine; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Phenytoin | 1987 |
Phenytoin and carbamazepine, alone and in combination: anticonvulsant and neurotoxic effects.
Topics: Animals; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Mice; Phenytoin | 1987 |
Analysis of serum concentration of phenobarbital, phenytoin, carbamazepine and carbamazepine 10,11-epoxide by solvent-recycled liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Management of trigeminal neuralgia.
Topics: Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia | 1987 |
Your CE topic this month (No. 20). Antiepileptic pharmacotherapy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Nursing, Practical; Phenytoin | 1986 |
Rapid measurement of anticonvulsant drug concentrations in the out-patient clinic, using HPLC with direct injection of plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin | 1987 |
Kindling of audiogenic seizures in the rat.
Topics: Acoustic Stimulation; Animals; Carbamazepine; Electroencephalography; Ethosuximide; Female; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1987 |
Psychosis associated with anticonvulsant toxicity.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Intellectual Disability; Male; Phenytoin; Psychoses, Substance-Induced | 1987 |
Prevalence of toxic anticonvulsant drug concentrations in mentally retarded persons with epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Intellectual Disability; Kinetics; Male; Phenytoin; Saliva; Sex Factors | 1986 |
Measuring anti-convulsant levels in the accident and emergency department.
Topics: Adult; Carbamazepine; Emergencies; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Prospective Studies | 1986 |
Pre-column switching techniques for the determination of drugs and metabolites in body fluids in research and routine analysis.
Topics: Animals; Blood Specimen Collection; Body Fluids; Carbamazepine; Cattle; Centrifugation; Chromatography, Ion Exchange; Humans; Pharmaceutical Preparations; Phenytoin; Serum Albumin, Bovine; Ultrafiltration | 1986 |
Decision-making in refractory epilepsy: an analysis based on computer simulation.
Topics: Carbamazepine; Computers; Epilepsy; Humans; Models, Theoretical; Patient Compliance; Phenytoin | 1986 |
Comparative pharmacokinetics of zonisamide (CI-912) in epileptic patients on carbamazepine or phenytoin monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Carbamazepine; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Humans; Isoxazoles; Kinetics; Male; Oxazoles; Phenytoin; Zonisamide | 1986 |
[Phenomenon of "paradoxical poisoning" during antiepileptic therapy].
Topics: Adult; Anticonvulsants; Barbiturates; Carbamazepine; Child; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1986 |
[Drug interactions with phenytoin and carbamazepine].
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin | 1986 |
Effect of influenza vaccine on serum anticonvulsant concentrations.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Influenza Vaccines; Influenza, Human; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Vaccination | 1986 |
Phenytoin vs carbamazepine in seizure disorder.
Topics: Carbamazepine; Epilepsy; Humans; Phenytoin | 1986 |
Effects of phenytoin and carbamazepine on human natural killer cell activity and genotoxicity in vitro.
Topics: Antibody-Dependent Cell Cytotoxicity; Carbamazepine; DNA, Single-Stranded; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Killer Cells, Natural; Monocytes; Phenytoin | 1987 |
Two episodes of erythema multiforme affecting one individual: sequential causation by phenytoin and carbamazepine.
Topics: Adult; Carbamazepine; Erythema Multiforme; Female; Humans; Phenytoin | 1986 |
Carbamazepine treatment for stuttering.
Topics: Adult; Carbamazepine; Female; Humans; Male; Phenytoin; Stuttering | 1987 |
[Anticonvulsants in the therapy of glioblastomas].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Drug Therapy, Combination; Female; Glioma; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis | 1986 |
Dexamethasone bioavailability: implications for DST research.
Topics: Biological Availability; Carbamazepine; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans; Phenobarbital; Phenytoin; Psychotic Disorders | 1987 |
Availability of drug assay results and dosage advice improves antiepileptic care in a specialist neurology outpatient clinic.
Topics: Adolescent; Adult; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Outpatient Clinics, Hospital; Pharmacy Service, Hospital; Phenytoin | 1985 |
The effects of long-term anticonvulsant drug therapy on vitamin D metabolites and mineral homeostasis in pregnant epileptic women and their newborns.
Topics: Adolescent; Adult; Anticonvulsants; Calcifediol; Calcitriol; Carbamazepine; Dihydroxycholecalciferols; Epilepsy; Female; Humans; Infant, Newborn; Minerals; Phenytoin; Pregnancy; Pregnancy Complications | 1985 |
Effect of chronic anticonvulsant monotherapy on lymphocyte subpopulations in adult epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Complement System Proteins; Epilepsy; Female; Humans; Immunoglobulins; Leukocyte Count; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; T-Lymphocytes | 1985 |
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays.
Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline | 1985 |
Surgical treatment of trigeminal neuralgia.
Topics: Carbamazepine; Cranial Fossa, Posterior; Electrosurgery; Humans; Middle Aged; Phenytoin; Stereotaxic Techniques; Trigeminal Nerve; Trigeminal Neuralgia | 1985 |
Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Electroshock; Female; Kinetics; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Time Factors; Valproic Acid | 1985 |
[Side effects of anticonvulsants on the peripheral nervous system and vestibulo-ocular functions].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Eye Movements; Female; Humans; Neural Conduction; Peripheral Nerves; Phenytoin; Primidone; Reflex, Stretch; Sensation; Vestibular Nuclei | 1985 |
Postictal pulmonary edema in children.
Topics: Carbamazepine; Child; Epilepsies, Partial; Furosemide; Humans; Intubation, Intratracheal; Male; Oxygen; Patient Compliance; Phenobarbital; Phenytoin; Positive-Pressure Respiration; Pulmonary Edema; Respiration, Artificial | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Drug compliance and seizure control in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Patient Compliance; Phenytoin; Valproic Acid | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Interictal EEG prediction of response to antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis; Sleep Deprivation; Valproic Acid | 1985 |
Evaluation of the effects of antiepileptic drugs on sleep-wakefulness patterns following 1 night total sleep deprivation in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenytoin; Sleep; Sleep Deprivation; Valproic Acid | 1985 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cognition; Humans; Infant; Memory Disorders; Phenobarbital; Phenytoin; Psychological Tests; Valproic Acid | 1985 |
Chronic valproic acid therapy and incidence of increases in venous plasma ammonia.
Topics: Adolescent; Adult; Aged; Ammonia; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
The optimum use of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Mortality from ischaemic heart disease among patients using anticonvulsive drugs: a case-control study.
Topics: Aged; Anticonvulsants; Barbiturates; Carbamazepine; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Epilepsy; Female; Finland; Humans; Male; Middle Aged; Phenytoin | 1985 |
[Antiepileptic monotherapy and combination therapy of simple focal seizures].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Evoked Potentials; Female; Humans; Male; Middle Aged; Phenytoin | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Recurrence; Risk; Succinimides; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
Serum concentrations of valproic acid: influence of dose and comedication.
Topics: Adolescent; Adult; Body Weight; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Use of total and free anticonvulsant serum levels in clinical practice.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Seizure disorders and pregnancy.
Topics: Carbamazepine; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications; Seizures | 1986 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1986 |
The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1986 |
[Bioavailabilities of three different phenytoin powders sold in Japan].
Topics: Adolescent; Biological Availability; Carbamazepine; Child; Child, Preschool; Humans; Japan; Phenytoin; Powders; Primidone | 1985 |
Drug-induced erythema multiforme: a possible immunologic pathogenesis.
Topics: Adult; Carbamazepine; Erythema Multiforme; Female; Humans; Lymphocyte Activation; Phenytoin; Seizures | 1985 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Differential effect of cimetidine on serum concentrations of carbamazepine and phenytoin.
Topics: Adolescent; Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 1985 |
Interpreting drug levels.
Topics: Carbamazepine; Digoxin; Phenobarbital; Phenytoin; Theophylline | 1985 |
[Transient monoclonal gammapathy in an angiolymphoblastic lymphadenopathy].
Topics: Aged; Carbamazepine; Humans; Hypergammaglobulinemia; Immunoblastic Lymphadenopathy; Immunoglobulin A; Male; Phenytoin | 1985 |
[Clinical pharmacology of carbamazepine--a comparison with phenytoin].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Female; Humans; Male; Phenytoin; Pregnancy | 1985 |
[A case of drug-induced lupus].
Topics: Adult; Anticonvulsants; Carbamazepine; Ethosuximide; Female; Humans; Lupus Erythematosus, Systemic; Phenytoin | 1985 |
Carbamazepine-phenytoin interaction: elevation of plasma phenytoin concentrations due to carbamazepine comedication.
Topics: Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Phenytoin | 1985 |
Epilepsy in a community--management and social impact.
Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Carbamazepine; Craniocerebral Trauma; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Seizures; Socioeconomic Factors; Stress, Physiological | 1985 |
Effect of antiepileptic drugs on short-latency somatosensory evoked potentials.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Reaction Time | 1985 |
Gas chromatographic determination of m- and p-hydroxyphenytoin in the urine of epileptic patients.
Topics: Adult; Aged; Carbamazepine; Chromatography, Gas; Epilepsy; Female; Humans; Hydrolysis; Male; Phenytoin; Urea | 1985 |
Epileptic amnesic attacks: benefit from antiepileptic drugs.
Topics: Aged; Amnesia; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin | 1985 |
Use of serum drug concentrations in outpatient clinics.
Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin | 1985 |
Cardiac side effects of phenytoin and carbamazepine. A dose-related phenomenon?
Topics: Adult; Carbamazepine; Female; Heart Block; Humans; Male; Middle Aged; Phenytoin; Tachycardia | 1985 |
A case report of phenytoin encephalopathy. Correlation between serum levels, seizure increase and E.E.G. spike and wave activity.
Topics: Brain Diseases; Carbamazepine; Child, Preschool; Convulsants; Drug Interactions; Electroencephalography; Humans; Male; Phenytoin; Seizures | 1985 |
Free thyroxin and free triiodothyronine as measured by equilibrium dialysis and analog radioimmunoassay in serum of patients taking phenytoin and carbamazepine.
Topics: Adolescent; Adult; Carbamazepine; Dialysis; Female; Humans; Male; Middle Aged; Phenytoin; Radioimmunoassay; Thyrotropin; Thyroxine; Triiodothyronine | 1985 |
Increased frequency of goitre in epileptic patients on long-term phenytoin or carbamazepine treatment.
Topics: Adolescent; Adult; Aged; Carbamazepine; Epilepsy; Female; Goiter; Humans; Male; Middle Aged; Phenytoin; Thyroid Gland | 1985 |
Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes.
Topics: Adult; Carbamazepine; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Liver; Male; Microsomes, Liver; Middle Aged; Organ Size; Phenobarbital; Phenytoin; Risk | 1985 |
Comparative evaluation of the Optimate and TDX analyzers using NCCLS guidelines.
Topics: Autoanalysis; Carbamazepine; Humans; Phenytoin; Primidone; Specimen Handling; Theophylline; Tobramycin | 1985 |
Parkinsonism induced by phenytoin.
Topics: Aged; Carbamazepine; Gait; Humans; Male; Parkinson Disease, Secondary; Phenytoin | 1985 |
The role of antiepileptics in sudden death in epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Death, Sudden; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1985 |
Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine.
Topics: Adult; Antipyrine; Biotransformation; Carbamazepine; Drug Interactions; Half-Life; Humans; Kinetics; Male; Phenytoin; Saliva | 1985 |
Comparative safety of carbamazepine & phenytoin in the treatment of epilepsy.
Topics: Carbamazepine; Cells, Cultured; Epilepsy; Humans; Lymphocytes; Phenytoin; Sister Chromatid Exchange | 1985 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Letter: Tests for drug allergy.
Topics: Adult; Carbamazepine; Drug Hypersensitivity; Epilepsy, Temporal Lobe; Humans; Lymphocyte Activation; Male; Phenytoin; Skin Tests | 1974 |
Letter: Treatment of hiccup.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Drug Therapy, Combination; Female; Hiccup; Humans; Male; Phenobarbital; Phenytoin | 1974 |
The effect of certain drugs on the plasma protein binding of phenytoin.
Topics: Anticonvulsants; Aspirin; Binding Sites; Blood Proteins; Carbamazepine; Dialysis; Diazepam; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Temperature; Thiazines; Ultrafiltration | 1973 |
Interference in the Zimmerman test for steroids.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Carbamazepine; Evaluation Studies as Topic; Humans; Methods; Nitrazepam; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Thiazines | 1974 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Thiazines | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Radiography; Recurrence; Skull; Time Factors | 1974 |
Exfoliative dermatitis due ot carbamazepine (tegretol).
Topics: Carbamazepine; Cephaloridine; Dermatitis, Exfoliative; Dibenzazepines; Female; Humans; Middle Aged; Phenytoin; Prednisone | 1968 |
Paroxysmal kinesignenic choreoathetosis. Report of a case relieved by carbamazepine.
Topics: Adolescent; Athetosis; Carbamazepine; Diazepam; Dibenzazepines; Diphenhydramine; Female; Humans; Huntington Disease; Lactose; Phenobarbital; Phenytoin | 1969 |
[Therapy in traumatic epilepsy].
Topics: Adult; Barbiturates; Bromides; Carbamazepine; Coma; Disabled Persons; Drug Resistance; Epilepsy, Post-Traumatic; Female; Follow-Up Studies; Humans; Male; Phenytoin; Primidone | 1971 |
Radiologic bone changes and hypocalcemia with anticonvulsant therapy in epilepsy.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Back Pain; Calcium; Carbamazepine; Diarrhea; Epilepsy; Female; Femur; Fractures, Bone; Humans; Hypocalcemia; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Radiography | 1972 |
Carbamazepine as an anticonvulsant: a pilot study.
Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Epilepsy; Eye Movements; Humans; Movement Disorders; Nausea; Phenytoin; Time Factors; Unconsciousness; Vomiting | 1974 |
The effect of tegretol on some elementary neuronal mechanisms.
Topics: Animals; Carbamazepine; Cats; Dibenzazepines; Epilepsy; Phenytoin; Synapses; Synaptic Transmission; Trigeminal Neuralgia | 1969 |
The role of inhibitory pathways in petit mal epilepsy.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Cats; Cerebral Cortex; Electric Stimulation; Epilepsy, Absence; Ethosuximide; Maxillary Nerve; Neural Inhibition; Phenytoin; Synaptic Transmission; Trigeminal Nerve; Trimethadione | 1972 |
Tic douloureux: etiology, refined treatment.
Topics: Carbamazepine; Electrocoagulation; Herpesviridae Infections; Humans; Methods; Phenytoin; Spinal Nerve Roots; Trigeminal Neuralgia | 1973 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; Cholecalciferol; Epilepsy, Tonic-Clonic; Humans; Ilium; Iron; Long-Term Care; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets | 1973 |
[Medicinal treatment planning in primary trigeminal neuralgia].
Topics: Carbamazepine; Depression, Chemical; Female; Humans; Male; Phenytoin; Synaptic Transmission; Time Factors; Trigeminal Neuralgia | 1973 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
"Dilatin" overdosage.
Topics: Anticonvulsants; Ataxia; Brain Neoplasms; Carbamazepine; Diagnosis, Differential; Dibenzazepines; Epilepsy; Humans; Nystagmus, Pathologic; Phenytoin; Thiazines | 1968 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
Diphenylhydantoin.
Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Epilepsy; Gingival Hyperplasia; Heart Arrest; Humans; Migraine Disorders; Neurotic Disorders; Nystagmus, Pathologic; Phenytoin; Polyarteritis Nodosa; Respiratory Insufficiency; Skin Diseases; Speech Disorders; Stevens-Johnson Syndrome; Trigeminal Neuralgia; Ventricular Fibrillation | 1971 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Phenobarbital; Phenytoin; Thiazines | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
Simultaneous determination of some antiepileptic drugs by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Colorimetry; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1974 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
Preliminary observations on the clinical pharmacology of carbamazepine ('Tegretol').
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Drug Interactions; Half-Life; Humans; Intestinal Absorption; Phenytoin | 1974 |
Letter: Digital hypoplasia and anticonvulsants during pregnancy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Diazepam; Female; Fingers; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Toes | 1974 |
A clinical trial with clonazepam (Ro 5-4023).
Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Fatigue; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitro Compounds; Phenytoin; Primidone; Time Factors; Vertigo | 1973 |
The diagnosis and management of paroxysmal trigeminal neuralgia in association with a temporomandibular joint dysfunction.
Topics: Arthritis, Rheumatoid; Autonomic Nerve Block; Carbamazepine; Dermatitis; Female; Humans; Indomethacin; Meprobamate; Middle Aged; Phenytoin; Physical Therapy Modalities; Temporomandibular Joint Dysfunction Syndrome; Trigeminal Neuralgia | 1974 |
The action of some anticonvulsant drugs on cobalt-induced epilepsy and on the bemegride threshold in alert cats.
Topics: Animals; Anticonvulsants; Bemegride; Carbamazepine; Cats; Cobalt; Diazepam; Electroencephalography; Epilepsies, Partial; Epilepsy; Phenobarbital; Phenytoin | 1972 |
Tic douloureux in Rochester, Minnesota, 1945-1969.
Topics: Adult; Age Factors; Aged; Analgesics; Carbamazepine; Ethanol; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Minnesota; Multiple Sclerosis; Neoplasms; Phenytoin; Sex Factors; Trigeminal Neuralgia; Vitamin B 12 | 1972 |
The effect of an iminostilbene derivative (G32883) on peripheral nerves.
Topics: Action Potentials; Animals; Carbamazepine; Electric Stimulation; Neural Conduction; Phenytoin; Rats; Sciatic Nerve; Tibial Nerve; Trigeminal Neuralgia | 1973 |
Neuralgia.
Topics: Anesthesia, Conduction; Carbamazepine; Cranial Nerves; Ergotamine; Herpes Zoster; Humans; Methysergide; Neuralgia; Occipital Lobe; Phenytoin; Postoperative Complications; Thoracic Surgery; Thorax; Trigeminal Neuralgia | 1973 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Osteomalacia due to phenytoin sodium. A case report with review of literature.
Topics: Adult; Bone and Bones; Calcium; Carbamazepine; Clavicle; Deficiency Diseases; Female; Folic Acid; Humans; Osteomalacia; Pelvis; Phenytoin; Radiography; Seizures; Spine; Vitamin D; Vitamin D Deficiency | 1973 |
Abdominal epilepsy.
Topics: Abdomen; Carbamazepine; Colic; Diagnosis, Differential; Electroencephalography; Epilepsy; Humans; Male; Middle Aged; Phenytoin; Unconsciousness | 1973 |
Neuropharmacology of SQ 10,996, a compound with several therapeutic indications.
Topics: Amides; Animals; Anticonvulsants; Antidepressive Agents; Anxiety; Behavior, Animal; Carbamazepine; Cats; Decerebrate State; Dibenzoxazepines; Electric Stimulation; Electroshock; Evoked Potentials; Female; Humans; Limbic System; Mice; Pentylenetetrazole; Phenytoin; Rats; Seizures; Trigeminal Nerve | 1973 |
Preliminary observations of serum carbamazepine concentration in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
Inherited tic douloureux.
Topics: Adult; Alcohols; Carbamazepine; Female; Humans; Male; Middle Aged; Pedigree; Phenytoin; Trigeminal Neuralgia | 1973 |
The influence of diphenylhydantoin and carbamazepine on the circadian rhythm of free urinary corticoids and on the suppressibility of the basal and the "impulsive" activity by dexamethasone.
Topics: Adrenal Cortex Hormones; Adult; Binding, Competitive; Carbamazepine; Circadian Rhythm; Depression, Chemical; Dexamethasone; Feedback; Female; Humans; Male; Phenytoin; Protein Binding; Time Factors | 1973 |
[Development inhibition in brain-damaged children due to anticonvulsants].
Topics: Anticonvulsants; Carbamazepine; Child; Child Development; Electroencephalography; Humans; Intellectual Disability; Intelligence Tests; Phenytoin; Primidone | 1973 |
[Pseudomyotonia (Isaacs' syndrome)].
Topics: Adolescent; Autonomic Nerve Block; Carbamazepine; Electromyography; Humans; Male; Muscle Tonus; Muscular Diseases; Phenytoin; Procaine; Syndrome; Tic Disorders | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Depression, Chemical; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Pain; Phenobarbital; Phenytoin; Trigeminal Neuralgia | 1973 |
Effect of anticonvulsive drugs on folate absorption and the cerebrospinal folate pump.
Topics: Adolescent; Adult; Aged; Carbamazepine; Depression, Chemical; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Male; Methods; Middle Aged; Phenytoin; Trigeminal Neuralgia | 1973 |
[Letter: Teratogenic hazards in antiepileptic therapy].
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1974 |
Interaction between doxycycline and barbiturates.
Topics: Adult; Aged; Amobarbital; Barbiturates; Carbamazepine; Doxycycline; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Male; Middle Aged; Pentobarbital; Phenobarbital; Phenytoin | 1974 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocytes; Nitrofurantoin; Phenytoin; Prednisone; Stevens-Johnson Syndrome; Sulfonamides; Thymidine; Trimethoprim; Tritium; Urticaria | 1974 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; Facial Muscles; Facial Nerve; Glioma; Humans; Lidocaine; Male; Muscle Contraction; Muscular Diseases; Myoclonus; Nerve Block; Phenytoin; Volition | 1974 |
Postsympathectomy neuralgia. Amelioration with diphenylhydantoin and carbamazepine.
Topics: Adult; Aged; Carbamazepine; Drug Therapy, Combination; Female; Ganglia, Autonomic; Humans; Intermittent Claudication; Male; Middle Aged; Neuralgia; Phenytoin; Postoperative Complications; Prospective Studies; Sympathectomy; Time Factors | 1974 |
Primary reading epilepsy.
Topics: Adolescent; Adult; Brain Stem; Carbamazepine; Drug Synergism; Electric Stimulation; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Humans; Jaw; Male; Oculomotor Muscles; Phenytoin; Reading; Tic Disorders | 1969 |
Carbamazepine in the treatment of tabetic lightning pains.
Topics: Adult; Aged; Carbamazepine; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Syphilis Serodiagnosis; Tabes Dorsalis; Treponema Immobilization Test | 1972 |
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
Topics: Benzyl Compounds; Carbamazepine; Chloroform; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Phthalic Acids; Primidone; Solubility; Spectrophotometry; Ultraviolet Rays | 1972 |
Antiepileptic drug concentrations in plasma. Clinical evaluation of 321 estimations in 237 unselected patients.
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Epilepsy; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Rapid routine determination of some anti-epileptic drugs in serum by gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin | 1972 |
GLC determination of carbamazepine in plasma.
Topics: Benzocycloheptenes; Carbamates; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
Epilepsy in multiple sclerosis.
Topics: Adolescent; Adult; Barbiturates; Basal Ganglia; Carbamazepine; Cerebral Cortex; Demyelinating Diseases; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Multiple Sclerosis; Phenytoin; Primidone | 1972 |
[Dialysis of drugs and poisons. 2].
Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine | 1972 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Forearm; Heel; Humans; Iodine Radioisotopes; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone | 1971 |
The syndrome of postherpetic neuralgia: complication and an approach to therapy.
Topics: Aged; Arm; Carbamazepine; Female; Herpes Zoster; Humans; Neuralgia; Paralysis; Phenytoin | 1969 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
[A case of pseudomyotonia cured by carbamazepine].
Topics: Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Electromyography; Female; Humans; Middle Aged; Motor Neurons; Muscle Contraction; Myotonia; Phenytoin | 1969 |
Some properties of a coma producing material obtained from mammalian brain.
Topics: Amylases; Animals; Blood Pressure; Brain Chemistry; Carbamazepine; Cats; Cerebral Cortex; Chromatography, Paper; Colon; Coma; Duodenum; Electroencephalography; Female; Guinea Pigs; Ileum; Mucoproteins; Muscle, Smooth; Nerve Tissue Proteins; Neuromuscular Junction; Phenytoin; Rabbits; Rats; Seizures; Uterus | 1970 |
Sphenopalatine gangionectomy for cluster headache.
Topics: Adult; Analgesics; Caffeine; Carbamazepine; Cortisone; Diazepam; Ergotamine; Female; Ganglia, Autonomic; Headache; Humans; Isoproterenol; Male; Methods; Methysergide; Middle Aged; Neuralgia; Palate; Phenytoin; Progesterone; Prognosis; Sphenoid Bone | 1970 |
[Anti-epileptic drugs in the treatment of essential trigeminal neuralgia].
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Dibenzazepines; Humans; Phenytoin; Trigeminal Neuralgia | 1970 |
[Determination of plasma concentrations of antiepileptics. Methodologic and clinical viewpoints].
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Dibenzazepines; Humans; Phenytoin; Spectrophotometry | 1971 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1971 |
[Correlation between the prescribed dose of anti-epileptic agents and the blood levels measured].
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1971 |
[The anti-epileptic and psychotropic properties of carbamazepine (Tegretol)].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dibenzazepines; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin | 1967 |
[Trigeminal neuralgia. Medical and surgical management in 50 cases].
Topics: Adult; Aged; Carbamazepine; Female; Humans; Male; Methods; Middle Aged; Occipital Bone; Phenytoin; Postoperative Complications; Temporal Bone; Trigeminal Neuralgia | 1968 |
Carbamazepine (Tegretol).
Topics: Agranulocytosis; Anemia, Aplastic; Blood Platelet Disorders; Carbamazepine; Dibenzazepines; Hematologic Diseases; Humans; Phenytoin; Thrombocytopenia; Trigeminal Neuralgia | 1968 |
Medical treatment of trigeminal neuralgia. With a note on the results of alcohol injection.
Topics: Carbamazepine; Ethanol; Humans; Mephenesin; Phenytoin; Sclerosing Solutions; Trigeminal Neuralgia | 1968 |
Pseudo-myotonia and myokymia.
Topics: Carbamazepine; Contracture; Electromyography; Humans; Male; Myotonia; Phenytoin | 1969 |
[Acute hepatic cell damage by simultaneous administration of isonicotinic acid hydrazide and antiepileptic agents in humans, (diphenylhydantoin or carbamazepin)].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Dibenzazepines; Drug Synergism; Female; Humans; Isoniazid; Male; Middle Aged; Phenytoin | 1969 |
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin | 1984 |
Anticonvulsant drug therapy in human pregnancy: effects on serum concentrations of vitamin D metabolites in maternal and cord blood.
Topics: 24,25-Dihydroxyvitamin D 3; Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Calcifediol; Calcitriol; Calcium; Carbamazepine; Cholecalciferol; Dihydroxycholecalciferols; Epilepsy; Female; Fetal Blood; Homeostasis; Humans; Phenytoin; Phosphates; Pregnancy; Pregnancy Complications; Vitamin D | 1984 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
[Effect of barbexaclone treatment on thyroid function in epileptic children and juveniles (author's transl)].
Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Propylamines; Succinimides; Thyroid Hormones | 1980 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Mechanisms of action of antiepileptic drugs.
Topics: Acetazolamide; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Chemical Phenomena; Chemistry; Humans; Paraldehyde; Phenytoin; Primidone; Seizures; Succinimides; Trimethadione; Valproic Acid | 1982 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
[Treatment of typical trigeminus neuralgias. Overview of the current state of drug and surgical therapy].
Topics: Adult; Antipsychotic Agents; Baclofen; Carbamazepine; Chlorphenesin; Electrocoagulation; Female; Humans; Male; Middle Aged; Muscle Hypotonia; Paresthesia; Phenytoin; Trigeminal Neuralgia | 1984 |
Hepatotoxicity of sodium valproate.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chemical and Drug Induced Liver Injury; Child; Fibrinogen; gamma-Glutamyltransferase; Humans; Middle Aged; Phenytoin; Prospective Studies; Retrospective Studies; Valproic Acid | 1983 |
A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Plasma concentrations of valproate during maintenance therapy in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Therapeutic aspects of kinesiogenic paroxysmal choreoathetosis and familial paroxysmal choreoathetosis of the Mount and Reback type.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Athetosis; Carbamazepine; Child; Chorea; Female; Haloperidol; Humans; Male; Middle Aged; Motor Activity; Pedigree; Phenytoin; Primidone; Valproic Acid | 1983 |
Plasma arginine vasopressin concentrations in epileptics under monotherapy.
Topics: Adult; Anticonvulsants; Arginine Vasopressin; Carbamazepine; Epilepsy; Humans; Phenytoin; Primidone; Valproic Acid | 1983 |
Serum anticonvulsant concentrations and the risk of drug induced skin eruptions.
Topics: Carbamazepine; Craniotomy; Drug Eruptions; Epilepsy; Humans; Phenytoin; Postoperative Complications | 1984 |
Role of inhibitory mechanisms in trigeminal neuralgia.
Topics: Animals; Baclofen; Carbamazepine; Cats; Electric Stimulation; Maxillary Nerve; Neural Inhibition; Phenobarbital; Phenytoin; Synaptic Transmission; Trigeminal Neuralgia; Trigeminal Nuclei | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1982 |
Inhibition of binding of [3H]batrachotoxinin A 20-alpha-benzoate to sodium channels by the anticonvulsant drugs diphenylhydantoin and carbamazepine.
Topics: Animals; Batrachotoxins; Carbamazepine; In Vitro Techniques; Ion Channels; Kinetics; Male; Neurotoxins; Phenytoin; Rats; Rats, Inbred Strains; Saxitoxin; Sodium; Synaptosomes | 1982 |
[Side-effects of phenytoin and carbamazepine on electrophysiologic functions of the peripheral and central nervous system].
Topics: Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsy; Evoked Potentials; Humans; Peripheral Nerves; Phenytoin; Synaptic Transmission | 1983 |
Inhibition of voltage-sensitive sodium channels in neuroblastoma cells and synaptosomes by the anticonvulsant drugs diphenylhydantoin and carbamazepine.
Topics: Animals; Batrachotoxins; Brain; Carbamazepine; Electric Conductivity; Ion Channels; Membrane Potentials; Neuroblastoma; Phenytoin; Rats; Sodium; Synaptosomes | 1984 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Semi-automated continuous-flow enzyme immunoassay for antiepileptic drugs in serum.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reagent Kits, Diagnostic | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Usefulness of enzyme multiplied immunoassay technique (EMIT) in the study of intoxications caused by anticonvulsive drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1983 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Performance of a new automated substrate-labeled fluorescence immunoassay system evaluated by comparative therapeutic monitoring of five drugs.
Topics: Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Stability; Fluorescent Antibody Technique; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Spectrometry, Fluorescence; Theophylline | 1984 |
Generalized tonic-clonic seizures in patients with complex-partial seizures: natural history and prognostic relevance.
Topics: Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Humans; Phenytoin; Primidone; Prognosis | 1983 |
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants.
Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1983 |
A survey of non-barbiturate anticonvulsant drug overdose reported to the Poisons Information Service (UK).
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Phenytoin; Poison Control Centers; United Kingdom; Valproic Acid | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Antiepileptic drugs and teratogenesis. How should patients, doctors and health authorities be counselled?
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Oxazoles; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Risk; Trimethadione; Valproic Acid | 1983 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1983 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
Antiepileptic drug therapy. Fine tuning the dosage regimen.
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Interactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
Serum and plasma for total and free anticonvulsant drug analyses: effects on EMIT assays and ultrafiltration devices.
Topics: Anticonvulsants; Carbamazepine; Humans; Immunoenzyme Techniques; Phenytoin; Plasma; Ultrafiltration; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epilepsies, Myoclonic; Ethosuximide; Female; Humans; Male; Phenytoin; Valproic Acid | 1984 |
Cluster headache with trigeminal neuralgia. An uncommon association that may be more than coincidental.
Topics: Adrenal Cortex Hormones; Adult; Baclofen; Carbamazepine; Chlorphenesin; Cluster Headache; Drug Therapy, Combination; Ergotamine; Ergotamines; Female; Humans; Lithium; Lithium Carbonate; Male; Methysergide; Middle Aged; Phenytoin; Trigeminal Neuralgia; Vascular Headaches | 1984 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Free level monitoring of antiepileptic drugs. Clinical usefulness and case studies.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Female; Humans; Male; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
Hepatic toxicity of antiepileptic drugs: a review.
Topics: Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Energy Metabolism; Epilepsy; Humans; Phenytoin; Valproic Acid | 1983 |
Pituitary responsiveness to gonadotrophin-releasing and thyrotrophin-releasing hormones in epileptic patients receiving carbamazepine or phenytoin.
Topics: Adult; Carbamazepine; Epilepsy; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Male; Phenytoin; Prolactin; Thyrotropin-Releasing Hormone | 1984 |
Effect of anticonvulsant drugs on thalamo-cortical and hippocampo-cortical self-sustained after-discharges in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Electric Stimulation; Electroencephalography; Epilepsy; Ethosuximide; Hippocampus; Kindling, Neurologic; Male; Phenytoin; Rats; Rats, Inbred Strains; Thalamus; Valproic Acid | 1984 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Summing up of the success so far gained through choice of drugs or combinations of drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Psychotropic Drugs; Valproic Acid | 1984 |
[The incidence of postoperative epilepsy and prophylactic anticonvulsants in patients with intracranial aneurysm].
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Valproic Acid | 1984 |
Nonsedative regimens in the treatment of epilepsy.
Topics: Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenytoin; Seizures; Valproic Acid | 1983 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Teratogenic effects of dosage levels and time of administration of carbamazepine, sodium valproate, and diphenylhydantoin on craniofacial development in the CD-1 mouse fetus.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Face; Female; Gestational Age; Maternal-Fetal Exchange; Mice; Phenytoin; Pregnancy; Skull; Teratogens; Valproic Acid | 1984 |
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Tryptophan | 1984 |
Anticonvulsant effects on the memory performance of epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Intelligence; Memory; Memory Disorders; Middle Aged; Phenytoin; Valproic Acid | 1984 |
Anticonvulsants, folic acid and memory dysfunction in epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Erythrocytes; Folic Acid; Humans; Memory Disorders; Middle Aged; Phenytoin; Valproic Acid | 1984 |
[Mono- or polytherapy of epilepsy?].
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Long-Term Care; Phenytoin | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Epilepsy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Infant; Medical History Taking; Narcolepsy; Phenobarbital; Phenytoin; Physical Examination; Sleep Wake Disorders | 1984 |
The effect of computer generated comments on the distribution of anticonvulsant concentrations.
Topics: Anticonvulsants; Carbamazepine; Chemistry, Clinical; Computers; Humans; Phenobarbital; Phenytoin | 1984 |
A comparison of plasma and saliva levels of carbamazepine and phenytoin as monotherapy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Humans; Middle Aged; Phenytoin; Saliva | 1984 |
Trigeminal neuralgia. Current concepts regarding etiology and pathogenesis.
Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia | 1984 |
Carbamazepine decreases catecholamine turnover in the rat brain.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbamazepine; Catecholamines; Dopamine; Dopamine beta-Hydroxylase; Female; Methoxyhydroxyphenylglycol; Methyltyrosines; Myocardium; Norepinephrine; Phenobarbital; Phenytoin; Probenecid; Rats; Rats, Inbred Strains | 1984 |
[Simultaneous determination of 4 anticonvulsant drugs by high pressure liquid chromatography (HPLC)].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Biotin; Carbamazepine; Carboxy-Lyases; Carboxylic Acids; Epilepsy; Female; Humans; Male; Methylmalonyl-CoA Decarboxylase; Phenobarbital; Phenytoin; Primidone | 1984 |
Statistical analysis of performance of a liquid chromatographic assay of anticonvulsants involving solvent-demixing extraction and reciprocal internal standardization.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1984 |
Systematic comparison of three basic methods of sample pretreatment for high-performance liquid chromatographic analysis of antiepileptic drugs using gas chromatography as a reference method.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Costs and Cost Analysis; Humans; Kinetics; Phenytoin; Reference Values | 1984 |
[Monitoring of antiepileptic therapy. A basis for the clinical use of plasma levels in the treatment of epilepsy].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Ethosuximide; Humans; Phenytoin; Primidone | 1984 |
Interactions of the anticonvulsants diphenylhydantoin and carbamazepine with adenosine on cerebral cortical neurons.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Male; Neurons; Phenytoin; Rats; Rats, Inbred Strains | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Primidone; Prognosis | 1984 |
Differential effect of antiepileptic and non-antiepileptic drugs on the reticular formation.
Topics: Action Potentials; Animals; Anticonvulsants; Baclofen; Carbamazepine; Cats; Dose-Response Relationship, Drug; Epilepsy; Humans; Neurons; Phenytoin; Reticular Formation | 1984 |
Single dose pharmacokinetic study of clobazam in normal volunteers and epileptic patients.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Enzyme Induction; Epilepsy; Female; Humans; Kinetics; Male; Phenytoin | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
High-dose monotherapy in treatment of intractable seizures.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Middle Aged; Phenytoin; Seizures | 1984 |
Phenytoin potentiates methamphetamine-induced behavior in mice.
Topics: Animals; Apomorphine; Behavior, Animal; Brain; Carbamazepine; Drug Synergism; Humans; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Phenytoin; Stereotyped Behavior; Tremor | 1984 |
Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine: individual variation in relation to seizure frequency and type.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1984 |
Trigeminal neuralgia: approaches to nursing care.
Topics: Carbamazepine; Female; Humans; Male; Methods; Middle Aged; Patient Care Planning; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1983 |
The influence of carbamazepine and phenytoin on memory and other aspects of cognitive function in new referrals with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Cognition Disorders; Decision Making; Epilepsy; Fixation, Ocular; Humans; Learning Disabilities; Memory Disorders; Memory, Short-Term; Middle Aged; Phenytoin; Psychomotor Disorders | 1984 |
Effects of phenobarbital, diphenylhydantoin and carbamazepine on thyroid function in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Phenobarbital; Phenytoin; Thyroid Gland | 1984 |
External quality assessment of serum drug determinations in the Nordic countries.
Topics: Anticonvulsants; Carbamazepine; Data Collection; Humans; Phenobarbital; Phenytoin; Quality Control; Reference Standards | 1984 |
The in vitro effect of phenytoin and carbamazepine on subpopulations of human blood mononuclear cells.
Topics: Carbamazepine; Dose-Response Relationship, Drug; Humans; Monocytes; Phagocytosis; Phenytoin; Rosette Formation; T-Lymphocytes | 1983 |
Effect of phenytoin and carbamazepine on subpopulations of mononuclear blood cells as defined by membrane antigens.
Topics: Antibodies, Monoclonal; Antigens, Surface; Carbamazepine; Humans; Monocytes; Phenytoin; T-Lymphocytes | 1984 |
Comparative binding studies of anticonvulsant drugs to bovine serum albumin.
Topics: Animals; Anticonvulsants; Carbamazepine; Cattle; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Phenytoin; Protein Binding; Serum Albumin; Serum Albumin, Bovine | 1983 |
Evaluation of the Abbott TDx for the stat measurement of phenobarbital, phenytoin, carbamazepine, and theophylline.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization; Humans; Immunoassay; Microcomputers; Phenobarbital; Phenytoin; Theophylline | 1983 |
Paroxysmal limb hemiataxia with crossed facial paresthesias in multiple sclerosis.
Topics: Adult; Ataxia; Carbamazepine; Face; Humans; Male; Multiple Sclerosis; Paresthesia; Phenytoin; Thrombocytopenia | 1983 |
A quantitative determination of anticonvulsant-induced bone demineralization by an improved X-ray densitometry technique.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anticonvulsants; Bone and Bones; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microcomputers; Middle Aged; Minerals; Osteomalacia; Phenobarbital; Phenytoin; Time Factors | 1983 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Metabolism of thyroid hormones in isolated rat hepatocytes: studies on the influences of carbamazepine and phenytoin.
Topics: Animals; Carbamazepine; Cells, Cultured; Liver; Male; Phenytoin; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1983 |
Comparative study on the teratogenicity of some antiepileptics in the rat.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Carbamazepine; Ethosuximide; Female; Phenytoin; Pregnancy; Rats | 1983 |
The effectiveness of prophylactic anticonvulsants following neurosurgery.
Topics: Anticonvulsants; Carbamazepine; Humans; Neurosurgery; Phenytoin; Postoperative Complications; Prospective Studies; Seizures | 1983 |
A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults.
Topics: Adult; Aged; Anticonvulsants; Behavior; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Random Allocation; Seizures | 1983 |
Antiepileptic agents--primidone, phenobarbital, phenytoin, and carbamazepine by reversed-phase liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1984 |
Effect of use of gel-barrier sampling tubes on determination of some antiepileptic drugs in serum.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Centrifugation; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Time Factors | 1984 |
Should alcohol withdrawal seizures be treated with anti-epileptic drugs?
Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Carbamazepine; Chlormethiazole; Female; Humans; Male; Middle Aged; Oxazepam; Pentobarbital; Phenytoin; Psychoses, Alcoholic; Seizures; Substance Withdrawal Syndrome | 1984 |
Baclofen in the treatment of neuralgia.
Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia | 1984 |
Prospective neurometric studies during the beginning of carbamazepine and phenytoin therapy.
Topics: Action Potentials; Adolescent; Adult; Carbamazepine; Cerebral Cortex; Electroencephalography; Electromyography; Epilepsy; Female; Humans; Male; Median Nerve; Muscles; Neural Conduction; Peroneal Nerve; Phenytoin; Prospective Studies; Sural Nerve; Time Factors | 1984 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Organic convergence spasm.
Topics: Adolescent; Alpha Rhythm; Brain; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Eye Movements; Female; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Spasm; Theta Rhythm | 1980 |
The treatment of "shooting" pain.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Valproic Acid | 1980 |
[Differential treatment of epilepsy patients].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin | 1980 |
Pharmacokinetics of anticonvulsant drugs.
Topics: Anticonvulsants; Binding, Competitive; Brain; Carbamazepine; Drug Interactions; Drug Tolerance; Epilepsy; Folic Acid; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Tissue Distribution; Valproic Acid | 1980 |
Adult-onset stuttering treated with anticonvulsants.
Topics: Adult; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Epilepsy, Post-Traumatic; Female; Humans; Phenobarbital; Phenytoin; Stuttering | 1981 |
Teratogenic effects of anticonvulsants.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Cleft Palate; Eyelid Diseases; Female; Humans; Mice; Palate; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1981 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Anticonvulsant-induced status epilepticus in Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Chlormethiazole; Clonazepam; Diazepam; Drug Combinations; Electroencephalography; Epilepsy, Absence; Female; Humans; Phenytoin; Primidone; Status Epilepticus | 1981 |
Effect of anticonvulsant drugs on inhibitory and excitatory pathways.
Topics: Animals; Carbamazepine; Cats; Electric Stimulation; Ethosuximide; Maxillary Nerve; Neural Pathways; Phenytoin; Time Factors; Valproic Acid | 1981 |
Pharmacologic advances in seizure control.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Humans; Kinetics; Phenytoin; Seizures; Status Epilepticus; Valproic Acid | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Quantitative evaluation of anticonvulsant effects on penicillin-induced spike foci in cats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electroencephalography; Ethosuximide; Penicillins; Phenytoin; Seizures; Valproic Acid | 1981 |
Specific modalities of therapy for inappropriate antidiuretic hormone secretion.
Topics: Aged; Carbamazepine; Demeclocycline; Female; Glucocorticoids; Humans; Inappropriate ADH Syndrome; Lung Diseases; Lung Neoplasms; Male; Phenytoin; Vasopressins | 1981 |
Recent advances in the treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1980 |
Daily fluctuations of dipropylacetate (DPA) serum level in epileptic patients.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Primidone; Time Factors; Valproic Acid | 1980 |
Anticonvulsant drugs used in the treatment of lancinating pain. A comparison.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Female; Humans; Male; Middle Aged; Pain; Phenytoin; Valproic Acid | 1981 |
Drugs in the treatment of tinnitus.
Topics: Amobarbital; Antidepressive Agents, Tricyclic; Carbamazepine; Ethanol; Humans; Lidocaine; Phenytoin; Primidone; Tinnitus; Valproic Acid | 1981 |
Plasma levels and pharmacokinetics of antipileptic drugs in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Biological Availability; Biotransformation; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Humans; Kinetics; Metabolic Clearance Rate; Phenytoin; Valproic Acid | 1981 |
Some behavioral effects of antiepileptic drugs during acute and prolonged treatment in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Motor Skills; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1981 |
The effects of anticonvulsants on memory function in epileptic patients: preliminary findings.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Memory; Memory, Short-Term; Mental Recall; Phenytoin; Valproic Acid | 1981 |
The effect of anticonvulsant drugs on the development of male rats and their fertility.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Fertility; Genitalia, Male; Male; Phenytoin; Rats; Rats, Inbred Strains; Sperm Count; Sperm Motility; Valproic Acid | 1982 |
Early prognosis of epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Prognosis; Prospective Studies; Recurrence | 1982 |
Effects of anti-epileptic drug treatment with carbamazepine or phenytoin on the oral state of children and adolescents.
Topics: Adolescent; Adult; Carbamazepine; Child; Dental Plaque; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Oral Health; Phenytoin; Saliva | 1982 |
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine | 1982 |
Therapeutic concentration of antiepileptic drugs and the severity of epileptogenesis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Isoxazoles; Phenytoin; Valproic Acid; Zonisamide | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Anticonvulsant activation of pain-suppressive systems.
Topics: Aldehyde Oxidoreductases; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Male; Neural Inhibition; Nociceptors; Periaqueductal Gray; Phenytoin; Rats; Rats, Inbred Strains; Succinate-Semialdehyde Dehydrogenase; Valproic Acid | 1982 |
Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex.
Topics: Amygdala; Animals; Benzodiazepinones; Carbamazepine; Cerebral Cortex; Clonazepam; Differential Threshold; Dose-Response Relationship, Drug; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1983 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
Early reports on drug interactions.
Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine | 1983 |
Anticonvulsant-induced aplastic anemia: increased susceptibility to toxic drug metabolites in vitro.
Topics: Anemia, Aplastic; Carbamazepine; Female; Humans; Lymphocytes; Male; Microsomes; Middle Aged; Mutation; Phenytoin | 1983 |
[Monitoring therapy by analysis of the drug concentration of saliva].
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1983 |
A rapid procedure for the simultaneous estimation of the anticonvulsant drugs, ethosuximide, phenobarbitone, phenytoin, and carbamazepine in serum using high-pressure liquid chromatography.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1983 |
A spectrophotometric method for simultaneous estimation of phenytoin and carbamazepine.
Topics: Carbamazepine; Humans; Oxidation-Reduction; Phenytoin; Spectrophotometry, Ultraviolet | 1983 |
Effects of carbamazepine and diphenylhydantoin on metrazol seizures during ontogenesis in rats.
Topics: Aging; Animals; Carbamazepine; Male; Pentylenetetrazole; Phenytoin; Rats; Rats, Inbred Strains; Seizures | 1983 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
Motor and sensory conduction velocities and electromyographic findings in man before and after carbamazepine treatment.
Topics: Carbamazepine; Electromyography; Epilepsy; Humans; Neural Conduction; Peripheral Nerves; Phenytoin | 1983 |
A dominantly inherited syndrome with continuous motor neuron discharges.
Topics: Adult; Aged; Carbamazepine; Child; Female; Humans; Male; Middle Aged; Motor Neurons; Neuromuscular Diseases; Pedigree; Phenytoin; Syndrome | 1983 |
Effects of phenytoin, carbamazepine, and clonazepam on cortex- and amygdala-evoked potentials.
Topics: Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Clonazepam; Evoked Potentials; Humans; Kindling, Neurologic; Phenytoin | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Hypercupraemia induced by antiepileptic drugs.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Copper; Electroencephalography; Humans; Male; Phenytoin; Zinc | 1983 |
Trigeminal neuralgia treated by radiofrequency coagulation.
Topics: Adult; Aged; Carbamazepine; Electrocoagulation; Female; Humans; Male; Middle Aged; Outcome and Process Assessment, Health Care; Phenytoin; Radio Waves; Recurrence; Time Factors; Trigeminal Neuralgia | 1983 |
Benign chronic orofacial pain. Clinical criteria and therapeutic approaches.
Topics: Biofeedback, Psychology; Carbamazepine; Chronic Disease; Humans; Nerve Block; Orthodontic Appliances, Removable; Patient Education as Topic; Phenytoin; Temporomandibular Joint Dysfunction Syndrome; Trigeminal Nerve; Trigeminal Neuralgia | 1983 |
Alcohol, other drugs and the fetus.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fetal Alcohol Spectrum Disorders; Fetus; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy | 1982 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
[Clinical significance of blood level-determinations of antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Phenytoin; Time Factors | 1980 |
A study of the action of anticonvulsant drugs on an experimental model of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Electric Stimulation; Epilepsy; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1980 |
Current treatment of tic douloureux.
Topics: Carbamazepine; Denervation; Humans; Microsurgery; Phenytoin; Sex Factors; Trigeminal Nerve; Trigeminal Neuralgia | 1980 |
Anticonvulsant drugs, cognitive function and memory.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsy; Humans; Male; Memory Disorders; Mental Recall; Phenytoin | 1980 |
The medical treatment of tinnitus.
Topics: Adult; Carbamazepine; Diethylcarbamazine; Female; Humans; Lidocaine; Myoclonus; Phenytoin; Primidone; Tinnitus | 1981 |
Carbamazepine. Pharmacology and clinical uses.
Topics: Adult; Alcohol Withdrawal Delirium; Arrhythmias, Cardiac; Behavior; Carbamazepine; Child; Diabetes Insipidus; Drug Interactions; Epilepsy; Female; Humans; Infant, Newborn; Kinetics; Male; Nervous System Diseases; Phenytoin; Pregnancy; Seizures | 1981 |
Therapeutic drug monitoring: a survey of sub- and supra-therapeutic serum drug levels in a large teaching hospital.
Topics: Carbamazepine; Digoxin; Drug Administration Schedule; Hospitals, Teaching; Humans; Pharmaceutical Preparations; Phenytoin; Theophylline | 1982 |
Some immunological reactions during chronic treatment with antiepileptic drugs.
Topics: Adult; Antibody Formation; B-Lymphocytes; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; HLA Antigens; Humans; Immunity, Cellular; Male; Phenobarbital; Phenytoin; T-Lymphocytes | 1981 |
Decreased serum 24,25-dihydroxyvitamin D concentration during long-term anticonvulsant therapy in adult epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Calcifediol; Calcitriol; Carbamazepine; Ergocalciferols; Humans; Middle Aged; Phenobarbital; Phenytoin | 1982 |
Serum vitamin D metabolites in epileptic patients treated with 2 different anti-convulsants.
Topics: 24,25-Dihydroxyvitamin D 3; Adult; Aged; Alkaline Phosphatase; Calcifediol; Calcitriol; Calcium; Carbamazepine; Dihydroxycholecalciferols; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenytoin | 1982 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
[A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Temperature | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Enzyme immunoassay of phenobarbital, phenytoin, primidone, carbamazepine and theophylline with the Abbott VP Bichromatic Analyzer.
Topics: Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1981 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
Stability of antiepileptic drug level in serum. Reliability of enzyme immunoassay method.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Time Factors | 1980 |
Evaluation of the provision of rapid drug plasma assays in an outpatient anticonvulsant clinic.
Topics: Ambulatory Care; Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Phenytoin | 1981 |
Anticonvulsant drugs determined by EMIT in spiked brain samples: a correlation with HPLC values.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
Serum elevation of high density lipoprotein (HDL) cholesterol in epileptic patients taking carbamazepine or phenytoin.
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Epilepsy; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenytoin | 1982 |
Analysis for carbamazepine and phenytoin in serum with a high-speed liquid chromatography system (Perkin-Elmer)
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenytoin; Reference Values | 1982 |
Do phenytoin and carbamazepine depress excitation and/or facilitate inhibition?
Topics: Animals; Carbamazepine; Cats; Depression, Chemical; Electrophysiology; Neural Inhibition; Neurons; Phenytoin | 1982 |
Anticonvulsant action of phenobarbital, diazepam, carbamazepine, and diphenylhydantoin in the electroshock test in mice after lesion of hippocampal pyramidal cells with intracerebroventricular kainic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Electroshock; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Seizures | 1982 |
Electrophysiological effects of diphenylhydantoin and carbamazepine on the peripheral and central nervous system.
Topics: Animals; Carbamazepine; Central Nervous System; Electroencephalography; Electromyography; Electrophysiology; Humans; Peripheral Nerves; Phenytoin; Rabbits | 1982 |
Differences between the concentrations of antiepileptic drugs in normal and pathological human brain.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1982 |
A newly devised reliable method for evaluating analgesic potencies of drugs on trigeminal pain.
Topics: Analgesics; Animals; Bradykinin; Carbamazepine; Dental Pulp; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Male; Morphine; Phenytoin; Rats; Rats, Inbred Strains; Time Factors; Trigeminal Neuralgia | 1982 |
Antiepileptic drugs and alpha 1-acid glycoprotein.
Topics: Adult; Carbamazepine; Humans; Orosomucoid; Phenytoin | 1982 |
Trigeminal neuralgia. A practical approach to treatment.
Topics: Baclofen; Carbamazepine; Chlorphenesin; Humans; Microsurgery; Phenytoin; Trigeminal Neuralgia | 1982 |
HLA antigens in epileptic patients with drug-induced immunodeficiency.
Topics: Adult; Anticonvulsants; Carbamazepine; Dysgammaglobulinemia; Epilepsy; Female; HLA Antigens; Humans; IgA Deficiency; Immunoglobulin M; Male; Phenytoin | 1982 |
Nonlinear kinetics of phenytoin in children.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epidermolysis Bullosa; Epilepsy; Female; Half-Life; Humans; Infant; Kinetics; Male; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin | 1982 |
Reversal by phenytoin of carbamazepine-induced water intoxication: a pharmacokinetic interaction.
Topics: Adult; Carbamazepine; Drug Antagonism; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Water; Water Intoxication | 1980 |
[Measurements of nerve conduction velocity during decreasing toxic diphenylhydantoin levels and the beginning of carbamazepine medication. A clinical neurophysiological documentation (author's transl)].
Topics: Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Motor Neurons; Neural Conduction; Phenytoin; Skin Temperature | 1981 |
Glossopharyngeal (vagoglossopharyngeal) neuralgia: a study of 217 cases.
Topics: Adolescent; Adult; Carbamazepine; Cocaine; Cranial Nerve Diseases; Geniculate Ganglion; Glossopharyngeal Nerve; Humans; Middle Aged; Movement; Neuralgia; Pain; Phenytoin; Trigeminal Neuralgia | 1981 |
Quantitative assessment of smooth-pursuit eye movements in healthy and epileptic subjects.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electrooculography; Epilepsy; Eye Movements; Humans; Intelligence; Phenobarbital; Phenytoin; Reflex, Abnormal | 1980 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Management of trigeminal neuralgia (tic douloureux).
Topics: Carbamazepine; Drug Therapy, Combination; Humans; Microsurgery; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1981 |
[Influence of anti-epileptic drugs on blood lipid parameters: preliminary data].
Topics: Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Humans; Lipids; Phenobarbital; Phenytoin; Triglycerides | 1981 |
Ictal effects of anticonvulsant medication withdrawal in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1981 |
Rapid microanalysis of anticonvulsants by high-performance thin-layer chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values | 1981 |
Comparison of anticonvulsant potencies of cyheptamide, carbamazepine, and phenytoin.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dibenzocycloheptenes; Electroshock; Male; Mice; Molecular Conformation; Phenytoin; Structure-Activity Relationship | 1981 |
Salivary anticonvulsant levels in children with epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Infant; Phenytoin; Saliva | 1981 |
Saliva carbamazepine and phenytoin level monitoring.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; Humans; Phenytoin; Saliva | 1981 |
[Pharmacological influences on the brain level and transport of GABA. I) Effect of various antipileptic drugs on brain levels of GABA].
Topics: Animals; Biological Transport; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Mice; Phenobarbital; Phenytoin | 1981 |
Effect of anticonvulsant and antidepressant drugs on iodothyronines in serum.
Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Mianserin; Phenobarbital; Phenytoin; Primidone; Thyroid Hormones | 1980 |
Carbamazepine, phenytoin and phenobarbital do not influence brain catecholamine uptake, in vivo, in male rats.
Topics: Animals; Brain; Carbamazepine; Catecholamines; Hydroxydopamines; Male; Nomifensine; Norepinephrine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
The effect of some anti-epilepsy drugs on enhancement of the monoamine-mediated behavioural responses following the administration of electroconvulsive shocks to rats.
Topics: Animals; Anticonvulsants; Apomorphine; Behavior, Animal; Carbamazepine; Clonidine; Diazepam; Dopamine; Electroshock; Lithium; Male; Norepinephrine; Phenytoin; Rats; Rats, Inbred Strains; Serotonin | 1981 |
Systematic method of development in liquid chromatography applied to the determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Solubility; Temperature | 1981 |
Treatment of tic douloureux: current concepts.
Topics: Aged; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1981 |
Spectrophotometric determination of phenytoin in the presence of other anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1981 |
[Monotherapy or polytherapy in epilepsy?].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Infant; Phenytoin | 1981 |
[Diagnosis of osteopathy caused by antiepileptic drugs].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Hand; Humans; Lumbar Vertebrae; Male; Middle Aged; Osteomalacia; Osteoporosis; Pelvis; Phenobarbital; Phenytoin; Radiography | 1981 |
Paroxysmal choreoathetosis: report of five cases and review of the literature.
Topics: Adolescent; Athetosis; Calcium; Carbamazepine; Ceruloplasmin; Child; Chorea; Humans; Male; Neurologic Examination; Phenytoin | 1980 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Interaction of lithium and phenytoin.
Topics: Carbamazepine; Drug Interactions; Humans; Lithium; Male; Middle Aged; Phenytoin; Polyuria | 1980 |
Plasma high-density lipoprotein cholesterol in epileptics treated with various anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides | 1980 |
Antiepileptic drug distribution in cerebral cortex, ammon's horn, and amygdala in man.
Topics: Adolescent; Adult; Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1980 |
Tonic seizures in a patient with multiple sclerosis.
Topics: Carbamazepine; Clonazepam; Female; Humans; Middle Aged; Multiple Sclerosis; Phenytoin; Seizures | 1980 |
Carbamazepine-induced leukocytosis.
Topics: Adult; Carbamazepine; Female; Humans; Leukocytosis; Neutrophils; Phenobarbital; Phenytoin; Seizures | 1980 |
Liquid-chromatographic method for simultaneous determination of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in plasma and urine.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Urine | 1980 |
Improved gas--liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin, carbamazepine and primidone in biological fluids.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Hypothyroidism induced by anti-epileptic therapy.
Topics: Aged; Carbamazepine; Female; Humans; Hypothyroidism; Middle Aged; Phenytoin | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
[A study of effects on antiepileptic drugs upon the hippocampal afterdischarge (author's transl)].
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electric Stimulation; Female; Hippocampus; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1980 |
Anticonvulsant activities and brain concentrations of cyheptamide and carbamazepine.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Chemical Phenomena; Chemistry; Dibenzocycloheptenes; Electroshock; Phenytoin; Structure-Activity Relationship | 1980 |
[Radiofrequency-thermocoagulation in the treatment of trigeminal neuralgia: analysis of 100 cases].
Topics: Adult; Aged; Carbamazepine; Cornea; Electrocoagulation; Female; Humans; Male; Middle Aged; Paresthesia; Phenytoin; Postoperative Complications; Radiography; Sensory Receptor Cells; Skull; Trigeminal Nerve; Trigeminal Neuralgia | 1980 |
Monitoring 2-ethyl-2-phenylmalonamide in serum by gas-liquid chromatography: application to retrospective study in epilepsy patients dosed with primidone.
Topics: Adult; Carbamazepine; Chromatography, Gas; Drug Interactions; Epilepsy; Humans; Malonates; Middle Aged; Phenylethylmalonamide; Phenytoin; Primidone | 1980 |
[Problems of therapeutic service in carbamazepine therapy].
Topics: Adult; Biotransformation; Body Weight; Carbamazepine; Child; Drug Interactions; Humans; Phenytoin | 1980 |
Arrhythmogenic epilepsy: an hypothesis.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Carbamazepine; Digoxin; Electroencephalography; Electrophysiology; Epilepsy; Humans; Male; Phenytoin; Tachycardia, Paroxysmal | 1980 |
[Effect of antiepileptic agents in myoclonus of spinal origin].
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Myoclonus; Phenytoin; Rats; Spinal Cord Diseases; Tetanus Antitoxin | 1980 |
Rapid quantitative determination of underivatized carbamazepine, phenytoin, phenobarbital and p-hydroxyphenobarbital in biological fluids by packed column gas chromatography.
Topics: Adult; Carbamazepine; Chromatography, Gas; Epilepsy; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
[Biotransformation of some antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Tic douloureux.
Topics: Carbamazepine; Chlorphenesin; Clonazepam; Female; Humans; Male; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1981 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Effects of long-term antiepileptic therapy on the catabolism of testosterone.
Topics: Adolescent; Adult; Androsterone; Anticonvulsants; Carbamazepine; Etiocholanolone; Humans; Male; Middle Aged; Phenytoin; Testosterone | 1995 |
Prediction of free levels of phenytoin and carbamazepine in patients comedicated with valproic acid.
Topics: Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Humans; Phenytoin; Valproic Acid | 1995 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Diseases; Male; Phenobarbital; Phenytoin; Prognosis; Syndrome | 1995 |
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy.
Topics: Carbamazepine; Case-Control Studies; Child; Cognition; Developmental Disabilities; Female; Humans; Intelligence Tests; Male; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Prospective Studies | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects | 1994 |
Neurodevelopment after in utero exposure to phenytoin and carbamazepine.
Topics: Carbamazepine; Child; Developmental Disabilities; Female; Humans; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects | 1994 |
Comparative anticonvulsant activity and neurotoxicity of 4-amino-N-(2,6-dimethylphenyl)phthalimide and prototype antiepileptic drugs in mice and rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Nervous System; Pentylenetetrazole; Phenytoin; Phthalimides; Rats; Rats, Sprague-Dawley; Seizures; Strychnine | 1995 |
Automated analysis of free and total concentrations of three antiepileptic drugs in plasma with on-line dialysis and high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dialysis; Epilepsy; Humans; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1995 |
Red cell folate levels in pregnant epileptic women.
Topics: Adult; Carbamazepine; Epilepsy; Erythrocytes; Female; Folic Acid; Follow-Up Studies; Humans; Phenytoin; Pregnancy | 1995 |
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Clone Cells; Cytokines; Drug Hypersensitivity; HLA-DR Antigens; Humans; Interleukin-5; Lymphocyte Activation; Lymphocytes; Phenytoin; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; Sulfonamides | 1995 |
Modulation of the gamma-aminobutyric acid type A receptor by the antiepileptic drugs carbamazepine and phenytoin.
Topics: Animals; Carbamazepine; Cell Line; Cerebral Cortex; Humans; Neurons; Phenytoin; Rats; Receptors, GABA-A | 1995 |
Carbamazepine, phenytoin, sex hormones, and sexual function in men with epilepsy.
Topics: Adolescent; Adult; Carbamazepine; Epilepsy; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Sex Hormone-Binding Globulin; Sexual Behavior; Testosterone | 1995 |
Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level/dose ratios in epileptic children.
Topics: Biotransformation; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Male; Oxidoreductases; Phenobarbital; Phenytoin | 1995 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Metabolism of carbamazepine and co-administered anticonvulsants during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenytoin; Pregnancy; Pregnancy Complications | 1995 |
Acute respiratory failure mediated by reactive drug metabolites.
Topics: Carbamazepine; Cell Death; Child; Erythema; Humans; Leukocytes, Mononuclear; Male; Phenytoin; Respiratory Distress Syndrome | 1995 |
The anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Bronchial Diseases; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Facial Dermatoses; Female; Humans; Male; Middle Aged; Pharyngitis; Phenytoin; Primidone; Stevens-Johnson Syndrome; Urticaria | 1993 |
Is there a pathophysiological and therapeutic link between panic disorder and epilepsy?
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Panic Disorder; Phenobarbital; Phenytoin | 1995 |
Aspirin and anticonvulsant interaction.
Topics: Animals; Aspirin; Carbamazepine; Disease Models, Animal; Drug Synergism; Electroshock; Female; Male; Phenobarbital; Phenytoin; Rats; Seizures | 1995 |
Humoral and cellular immune parameters in untreated and phenytoin-or carbamazepine-treated epileptic patients.
Topics: Adolescent; Adult; Aged; Antibody Formation; B-Lymphocytes; Carbamazepine; Complement C3; Complement C4; Epilepsy; Female; Humans; Immunity, Cellular; Immunoglobulins; Male; Middle Aged; Phenytoin; T-Lymphocyte Subsets | 1994 |
Drugs for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Phenytoin; Valproic Acid | 1995 |
[Disorders of color perception and increase glare sensitivity in phenytoin and carbamazepine therapy. Ocular side effects of anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Color Perception Tests; Color Vision Defects; Contrast Sensitivity; Epilepsy; Female; Humans; Male; Night Blindness; Phenytoin | 1995 |
Epileptic seizures in subjects previously affected by disorders of arousal.
Topics: Adolescent; Adult; Arousal; Carbamazepine; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenytoin; Sleep Wake Disorders | 1995 |
[Sensitive physiologic perceptual tests for ocular side effects of drugs exemplified by various anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Color Perception; Contrast Sensitivity; Dark Adaptation; Epilepsy; Female; Flicker Fusion; Humans; Male; Phenytoin; Psychophysics; Retina; Sensory Thresholds; Valproic Acid; Visual Perception | 1995 |
Anticonvulsants suppress c-Fos protein expression in spinal cord neurons following noxious thermal stimulation.
Topics: Animals; Anticonvulsants; Carbamazepine; Hot Temperature; Male; Neurons; Phenytoin; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Spinal Cord; Valproic Acid | 1995 |
Treatment of "benign" partial epilepsies of childhood, including atypical forms.
Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Carbamazepine; Child; Child, Preschool; Clobazam; Electroencephalography; Epilepsies, Partial; Humans; Phenytoin; Primidone; Sleep, REM; Thiazines; Treatment Outcome | 1995 |
[Changes in drug therapy and in seizure frequency in an institution for epilepsy patients between 1971 and 1986].
Topics: Aged; Aged, 80 and over; Anticonvulsants; Barbiturates; Carbamazepine; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Succinimides; Valproic Acid | 1994 |
The stability of anticonvulsant drugs in whole blood.
Topics: Anticonvulsants; Carbamazepine; Drug Stability; Drug Storage; Humans; Phenobarbital; Phenytoin; Temperature; Valproic Acid | 1994 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Life Style; Male; Middle Aged; Phenytoin; Prognosis; Sleep Deprivation; Stress, Physiological; Time Factors; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 1995 |
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid | 1994 |
Comparison of phenytoin and carbamazepine serum concentrations measured by high-performance liquid chromatography, the standard TDx assay, the enzyme multiplied immunoassay technique, and a new patient-side immunoassay cartridge system.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Enzyme Multiplied Immunoassay Technique; Humans; Immunoassay; Phenytoin; Reagent Kits, Diagnostic; Regression Analysis | 1994 |
A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report.
Topics: Adult; Carbamazepine; Cerebral Infarction; Dose-Response Relationship, Drug; Epilepsies, Partial; Female; Follow-Up Studies; Gingival Hyperplasia; Humans; Middle Aged; Oral Hygiene; Phenytoin | 1994 |
Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Carbamazepine; Drug Synergism; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
A comparative study of serum F protein and other liver function tests as an index of hepatocellular damage in epileptic patients.
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aspartate Aminotransferases; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Female; gamma-Glutamyltransferase; Humans; Isoantigens; Liver Function Tests; Male; Middle Aged; Phenytoin; Valproic Acid | 1994 |
Influence of carbamazepine and phenytoin on spontaneous activity of cerebellar neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebellar Cortex; Electrophysiology; Male; Microelectrodes; Neurons; Phenytoin; Rats; Rats, Wistar | 1994 |
Antiepileptics in the elderly. Pharmacoepidemiology and pharmacokinetics.
Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Health Surveys; Homes for the Aged; Humans; Minnesota; Nursing Homes; Phenytoin; United States; Valproic Acid | 1994 |
Enhanced differential diagnosis of anticonvulsant hypersensitivity reactions by an integrated Bayesian and biochemical approach.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Carbamazepine; Cell Death; Child; Diagnosis, Differential; Drug Eruptions; Female; Humans; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; Predictive Value of Tests; Sensitivity and Specificity | 1994 |
Changes of thyroid hormone levels in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Phenytoin; Thyrotropin; Thyroxine; Triiodothyronine; Valproic Acid | 1994 |
Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs.
Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dihydrotestosterone; Epilepsies, Partial; Epilepsy, Generalized; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Phenobarbital; Phenytoin; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Thyrotropin-Releasing Hormone | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Continuous muscle fibre activity (Isaacs' syndrome) in infancy: a report of two cases.
Topics: Baclofen; Carbamazepine; Electromyography; Female; Humans; Infant, Newborn; Male; Muscles; Muscular Diseases; Phenytoin; Syndrome; Treatment Failure | 1994 |
Alternatives to least squares linear regression analysis for computation of standard curves for quantitation by high performance liquid chromatography: applications to clinical pharmacology.
Topics: Analysis of Variance; Carbamazepine; Chromatography, High Pressure Liquid; Deuterium; Humans; Least-Squares Analysis; Pharmacology, Clinical; Phenytoin; Reference Values; Regression Analysis | 1994 |
Bone mineral density measured by dual-energy x-ray absorptiometry and novel markers of bone formation and resorption in patients on antiepileptic drugs.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Bone Density; Bone Development; Bone Resorption; Calcium; Carbamazepine; Collagen; Collagen Type I; Epilepsy; Female; Femur; Humans; Hydroxycholecalciferols; Lumbar Vertebrae; Male; Middle Aged; Osteocalcin; Parathyroid Hormone; Peptide Fragments; Peptides; Phenytoin; Procollagen | 1994 |
Synthesis of polymer-coated mixed-functional packing materials for direct analysis of drug-containing serum and plasma by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Polymers; Silicon Dioxide | 1994 |
Effects of the conventional anticonvulsants, phenytoin, carbamazepine, and valproic acid, on sodium-potassium-adenosine triphosphatase in acute ischemic brain.
Topics: Animals; Carbamazepine; Cerebral Cortex; Cerebral Infarction; Dose-Response Relationship, Drug; Male; Phenytoin; Premedication; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Valproic Acid | 1994 |
Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents.
Topics: Animals; Anticonvulsants; Brain Ischemia; Carbamazepine; Cerebral Arteries; Electrophysiology; Electroshock; Imidazoles; Lamotrigine; Male; Mice; Phenytoin; Piperazines; Rats; Rats, Inbred F344; Seizures; Sodium Channels; Thiazoles; Triazines | 1994 |
Simple and accurate high-performance liquid chromatographic method for the measurement of three antiepileptics in therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1993 |
Determination of drugs by direct injection of plasma into a biocompatible extraction column based on a protein-entrapped hydrophobic phase.
Topics: Biocompatible Materials; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenytoin; Propranolol; Reproducibility of Results | 1994 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet | 1994 |
Carbamazepine offers no psychotropic advantage over phenytoin in adult epileptic subjects.
Topics: Adult; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Personality Inventory; Phenytoin | 1993 |
Pregnancy, epilepsy, management and outcome: a 10-year perspective.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Birth Weight; Carbamazepine; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant, Newborn; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Risk Factors; Valproic Acid | 1993 |
Interaction between valproate and branched-chain amino acid metabolism.
Topics: Adult; Amino Acids, Branched-Chain; Carbamazepine; Drug Therapy, Combination; Female; Humans; Isoleucine; Male; Oxidation-Reduction; Phenytoin; Urine; Valproic Acid | 1994 |
Anticonvulsant hypersensitivity.
Topics: Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Neutropenia; Phenytoin; Skin Diseases | 1994 |
Seizure exacerbation and status epilepticus related to carbamazepine-10,11-epoxide.
Topics: Adult; Age of Onset; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Seizures; Status Epilepticus | 1994 |
[Repetitive serum determinations of anticonvulsants in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Time Factors; Treatment Refusal | 1993 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted | 1993 |
Prolonged duration of succinylcholine in patients receiving anticonvulsants: evidence for mild up-regulation of acetylcholine receptors?
Topics: Acetylcholine; Adult; Anesthesia, Intravenous; Carbamazepine; Drug Interactions; Female; Humans; Male; Muscle Contraction; Neuromuscular Junction; Phenytoin; Potassium; Reaction Time; Receptors, Cholinergic; Succinylcholine; Time Factors; Ulnar Nerve; Up-Regulation | 1993 |
Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy.
Topics: Amino Acids; Aminocaproates; Amygdala; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Epilepsies, Partial; Female; Kindling, Neurologic; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1993 |
Differential action of phenytoin and carbamazepine on cortical interhemispheric responses in young but not in adult rats.
Topics: Aging; Analysis of Variance; Animals; Carbamazepine; Electric Stimulation; Epilepsy, Tonic-Clonic; Male; Pentylenetetrazole; Phenytoin; Rats; Rats, Wistar; Somatosensory Cortex | 1993 |
[Rasmussen syndrome].
Topics: Acyclovir; Carbamazepine; Child, Preschool; Electroencephalography; Encephalitis; Epilepsies, Partial; Humans; Hungary; Intellectual Disability; Magnetic Resonance Imaging; Male; Phenytoin; Syndrome; Tomography, X-Ray Computed | 1993 |
Polysomnographical study in the patients of frontal lobe epilepsy with ictal automatism.
Topics: Automatism; Basal Ganglia; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy, Frontal Lobe; Epilepsy, Tonic-Clonic; Evoked Potentials; Frontal Lobe; Humans; Male; Phenytoin; Polysomnography; Sleep Stages | 1993 |
[The effects of phenytoin and carbamazepine on the cognitive function of epileptic patients].
Topics: Attention; Carbamazepine; Cognition; Epilepsy, Generalized; Humans; Memory; Phenytoin | 1993 |
Trigeminal neuralgia (tic douloureux).
Topics: Baclofen; Carbamazepine; Diagnosis, Differential; Humans; Phenytoin; Trigeminal Neuralgia | 1993 |
Unmasking the significant enzyme-inducing effects of phenytoin on serum carbamazepine concentrations during phenytoin withdrawal.
Topics: Adult; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Humans; Male; Middle Aged; Phenytoin | 1993 |
Pharmacological protection of CNS white matter during anoxia: actions of phenytoin, carbamazepine and diazepam.
Topics: Action Potentials; Animals; Axons; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Female; Hypoxia; Optic Nerve; Optic Nerve Diseases; Phenytoin; Rats | 1993 |
Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Saliva; Spectrophotometry, Ultraviolet | 1993 |
Lamotrigine, phenytoin and carbamazepine interactions on the sodium current present in N4TG1 mouse neuroblastoma cells.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Lamotrigine; Mice; Neuroblastoma; Phenytoin; Sodium Channels; Triazines; Tumor Cells, Cultured | 1993 |
Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Erythrocytes; In Vitro Techniques; Isoxazoles; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1993 |
Anticonvulsant withdrawal.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition; Humans; Phenytoin | 1993 |
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
Topics: Adult; Animals; Anticonvulsants; Autoantibodies; Autoantigens; Carbamazepine; Cell Line; Cross Reactions; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Hypersensitivity; Endoplasmic Reticulum; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Inactivation, Metabolic; Isoenzymes; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats | 1993 |
[Diagnosis and therapy of trigeminal neuralgia].
Topics: Carbamazepine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nerve Block; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia | 1993 |
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures | 1993 |
Five years of anticonvulsant monitoring on site at the epilepsy clinic.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Prospective Studies; Scotland; Time Factors; Valproic Acid | 1993 |
An audit of therapeutic drug monitoring of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Monitoring; Epilepsy; Humans; Medical Audit; Northern Ireland; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Low serum concentration of all-trans and 13-cis retinoic acids in patients treated with phenytoin, carbamazepine and valproate. Possible relation to teratogenicity.
Topics: Adult; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Isotretinoin; Male; Middle Aged; Phenytoin; Teratogens; Tretinoin; Valproic Acid | 1995 |
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases | 1995 |
A model for estimating individualized valproate clearance values in children.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Metabolic Clearance Rate; Models, Theoretical; Pharmacokinetics; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Analysis of anticonvulsant and neurotoxic responses to combination therapy with carbamazepine, felbamate and phenytoin by response-surface modeling.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Felbamate; Male; Mice; Phenylcarbamates; Phenytoin; Postural Balance; Propylene Glycols; Regression Analysis | 1995 |
Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Female; Flicker Fusion; Half-Life; Humans; Male; Midazolam; Middle Aged; Phenytoin; Sleep | 1996 |
Pharmacology of cortical epileptic afterdischarges in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Valproic Acid | 1996 |
Normal serum free thyroid hormone concentrations in patients treated with phenytoin or carbamazepine. A paradox resolved.
Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Carrier Proteins; Humans; Phenytoin; Seizures; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1996 |
Effect of valproate on cerebral metabolism and blood flow: an 18F-2-deoxyglucose and 15O water positron emission tomography study.
Topics: Adult; Brain; Carbamazepine; Cerebrovascular Circulation; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Oxygen Radioisotopes; Phenobarbital; Phenytoin; Tomography, Emission-Computed; Valproic Acid; Water | 1996 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
[Study of the influence of anticonvulsant treatment on thyroid function].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Enzyme-Linked Immunosorbent Assay; Epilepsy; Female; Humans; Hypothyroidism; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Thyroid Gland; Thyroid Hormones; Thyrotropin; Valproic Acid | 1995 |
Influence of D-cycloserine on the anticonvulsant activity of phenytoin and carbamazepine against electroconvulsions in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Carbamazepine; Cycloserine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Humans; Male; Memory; Mice; Motor Activity; Phenytoin; Seizures | 1996 |
Porphyria cutanea tarda in a patient on chronic ambulatory peritoneal dialysis.
Topics: Adult; Anticonvulsants; Carbamazepine; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Phenytoin; Phlebotomy; Porphyria Cutanea Tarda; Porphyrins; Seizures | 1996 |
Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs.
Topics: Acetone; Acetonitriles; Anticonvulsants; Biocompatible Materials; Carbamazepine; Cyanoacrylates; Diffusion; Drug Compounding; Drug Delivery Systems; Ethanol; Ethosuximide; Freeze Fracturing; Membranes, Artificial; Microscopy, Electron; Phenytoin; Poloxalene; Scattering, Radiation; Surface-Active Agents; Tissue Adhesives; Triglycerides | 1996 |
Protection against veratridine toxicity in rat cortical cultures: relationship to sodium channel blockade.
Topics: Animals; Carbamazepine; Cell Death; Cells, Cultured; Cerebral Cortex; Lidocaine; Neuroprotective Agents; Patch-Clamp Techniques; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Veratridine; Vinca Alkaloids | 1995 |
Clearance of phenytoin and valproic acid is affected by a small body weight reduction in an epileptic obese patient: a case study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Half-Life; Humans; Metabolic Clearance Rate; Obesity; Phenobarbital; Phenytoin; Valproic Acid; Weight Loss | 1996 |
Infant monkey hyperexcitability after prenatal exposure to antiepileptic compounds.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamazepine; Dioxolanes; Disease Models, Animal; Female; Humans; Hyperkinesis; Macaca fascicularis; Male; Maternal-Fetal Exchange; Memory; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects | 1996 |
Selective liver enzyme induction by carbamazepine and phenytoin in Chinese epileptics.
Topics: Acetaminophen; Adult; Anticonvulsants; Carbamazepine; China; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Glucuronates; Humans; Hydrocortisone; Liver; Male; Phenytoin | 1996 |
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide | 1996 |
Intracerebroventricular pertussis toxin enhances sensitivity to chemical convulsants and decreases the protective efficacy of carbamazepine in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Drug Synergism; GTP-Binding Proteins; Injections, Intraventricular; Male; Mice; Pertussis Toxin; Phenytoin; Seizures; Sensitivity and Specificity; Virulence Factors, Bordetella | 1996 |
Salivary protein composition in epileptic patients on different medications.
Topics: Adult; Aged; Albumins; Amylases; Anticonvulsants; Carbamazepine; Cystatin C; Cystatins; Cysteine Proteinase Inhibitors; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Immunoglobulin A, Secretory; Male; Middle Aged; Phenytoin; Polypharmacy; Saliva; Salivary Cystatins; Salivary Proteins and Peptides; Secretory Rate; Valproic Acid | 1996 |
Choroid plexus compression of glossopharyngeal nerve in patients with glossopharyngeal neuralgia.
Topics: Aged; Carbamazepine; Choroid Plexus; Female; Follow-Up Studies; Glossopharyngeal Nerve; Humans; Male; Medulla Oblongata; Middle Aged; Nerve Compression Syndromes; Neuralgia; Phenytoin; Retreatment | 1996 |
Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: phenytoin, carbamazepine, and phenobarbital.
Topics: Animals; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred ICR; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Thalamus | 1996 |
Quantitative analysis of mixtures of metal-carbonyl complexes by Fourier-transform infrared spectroscopy: application to the simultaneous double immunoassay of antiepileptic drugs by the nonisotopic carbonyl metalloimmunoassay method.
Topics: Animals; Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Haptens; Humans; Immunoassay; Molecular Structure; Organometallic Compounds; Phenobarbital; Phenytoin; Spectroscopy, Fourier Transform Infrared | 1996 |
Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 9; Diagnostic Errors; Electroencephalography; Epilepsy, Generalized; Ethosuximide; Female; Hodgkin Disease; Humans; Intellectual Disability; Lupus Erythematosus, Systemic; Magnetic Resonance Imaging; Myoclonus; Phenytoin; Pseudolymphoma; Trisomy; Valproic Acid | 1996 |
Elevated plasma alpha 1-acid glycoprotein levels: lack of connection to resistance to vecuronium blockade induced by anticonvulsant therapy.
Topics: Adult; Alprazolam; Anticonvulsants; Atropine; Biomarkers; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hydroxyzine; Hypnotics and Sedatives; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgery; Orosomucoid; Phenobarbital; Phenytoin; Vecuronium Bromide | 1997 |
Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Asthma; Avoidance Learning; Benzamides; Bronchodilator Agents; Carbamazepine; Drug Interactions; Electroshock; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Phenytoin; Psychomotor Performance; Tetrazoles; Valproic Acid | 1996 |
Population pharmacokinetics of felbamate in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Felbamate; Humans; Infant; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Seizures; Valproic Acid | 1997 |
Simultaneous determination of phenytoin and carbamazepine in human hair by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Hair; Humans; Phenytoin | 1997 |
Fixed drug eruption to three anticonvulsant drugs: an unusual case of polysensitivity.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Humans; Male; Phenytoin; Valproic Acid | 1997 |
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid | 1997 |
Differential block of two types of sodium channels by anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Ganglia, Spinal; Neurons; Phenytoin; Rats; Sodium Channels; Tetrodotoxin | 1996 |
Color vision tests for early detection of antiepileptic drug toxicity.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Color Perception; Epilepsy; Humans; Osmolar Concentration; Phenytoin; Valproic Acid; Vision Disorders; Vision Tests | 1997 |
Phenytoin and carbamazepine: differential inhibition of sodium currents in small cells from adult rat dorsal root ganglia.
Topics: Animals; Anticonvulsants; Carbamazepine; Cells, Cultured; Ganglia, Spinal; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Rats; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin | 1997 |
Topiramate for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Fructose; Humans; Phenytoin; Topiramate; Valproic Acid | 1997 |
Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications.
Topics: Animals; Anticonvulsants; Carbamazepine; Hippocampus; Kinetics; Membrane Potentials; Neurons; Phenytoin; Rats; Rats, Inbred Strains; Sodium; Sodium Channel Blockers; Sodium Channels | 1997 |
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid | 1997 |
Optimized high-performance liquid chromatographic method for determination of lamotrigine in serum with concomitant determination of phenytoin, carbamazepine, and carbamazepine epoxide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenytoin; Triazines | 1997 |
Bone status after long-term anticonvulsant therapy in epileptic patients: evaluation using quantitative ultrasound of calcaneus and phalanges.
Topics: Adult; Anticonvulsants; Calcaneus; Carbamazepine; Case-Control Studies; Drug Therapy, Combination; Epilepsy; Female; Fingers; Humans; Osteomalacia; Phenytoin; Time Factors; Ultrasonography | 1997 |
[Serum digitoxin in concomitant use of antiepileptics in routine therapy].
Topics: Anticonvulsants; Antidepressive Agents; Carbamazepine; Digitoxin; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Lithium Compounds; Male; Phenobarbital; Phenytoin | 1997 |
A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes.
Topics: Acetaminophen; Animals; Anticonvulsants; Biological Assay; Carbamazepine; Cell Count; Cell Survival; Female; Fluorescence; Humans; In Vitro Techniques; Lymphocytes; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits | 1997 |
AWD 140-190: a new anticonvulsant with a very good margin of safety.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Male; Mice; Morpholines; Phenytoin; Proline; Rats; Rats, Sprague-Dawley; Valproic Acid | 1997 |
Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity; Female; Hospitalization; Humans; Male; Medical Records; Middle Aged; Phenytoin; Risk; Skin Diseases; Valproic Acid | 1997 |
[Pharmacokinetic variations in anticonvulsants in Mexican epileptic women during different stages of the postpartum period].
Topics: Animals; Anticonvulsants; Carbamazepine; Cricetinae; Epilepsy; Female; Humans; Milk, Human; Phenytoin; Postpartum Period; Pregnancy; Pregnancy Complications | 1997 |
Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbamazepine; Cohort Studies; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Procarbazine; Retrospective Studies; Valproic Acid | 1997 |
Extrashot-ODS, a syringe-type minicolumn sample injector for a reversed-phase high-performance liquid chromatographic column. Application to antiepileptics in human sera.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1997 |
Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Isoxazoles; Phenobarbital; Phenytoin; Zonisamide | 1997 |
Vigabatrin versus carbamazepine and phenytoin in kainic acid-treated pubescent rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Enzyme Inhibitors; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Kainic Acid; Male; Phenytoin; Rats; Rats, Wistar; Vigabatrin | 1997 |
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids | 1997 |
Anticonvulsant cross-sensitivity.
Topics: Anticonvulsants; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin | 1997 |
Management of refractory neurocardiogenic syncope.
Topics: Adult; Carbamazepine; Humans; Male; Middle Aged; Phenytoin; Recurrence; Syncope, Vasovagal | 1998 |
If a first antiepileptic drug fails to control a child's epilepsy, what are the chances of success with the next drug?
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Drug Administration Schedule; Epilepsy; Follow-Up Studies; Humans; Nova Scotia; Phenobarbital; Phenytoin; Prognosis; Remission Induction; Treatment Failure | 1997 |
Weak blockade of AMPA receptor-mediated depolarisations in the rat cortical wedge by phenytoin but not lamotrigine or carbamazepine.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Lamotrigine; Male; Phenytoin; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Triazines | 1997 |
BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Kindling, Neurologic; Male; Neuroprotective Agents; Phenytoin; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures | 1997 |
[Neurocysticercosis in children: clinical and radiological analysis and prognostic factors in 54 patients].
Topics: Adolescent; Albendazole; Anthelmintics; Anticonvulsants; Brain; Brain Diseases; Carbamazepine; Child; Child, Preschool; Cysticercosis; Epilepsy, Tonic-Clonic; Female; Humans; Male; Phenytoin; Prognosis; Tomography, X-Ray Computed | 1997 |
[Optimisation of epilepsy monotherapy (clinico-pharmacological study)].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy; Follow-Up Studies; Half-Life; Humans; Phenobarbital; Phenytoin; Treatment Outcome | 1997 |
Disturbances in biotin metabolism in children undergoing long-term anticonvulsant therapy.
Topics: Anticonvulsants; Biotin; Carbamazepine; Child; Female; Humans; Male; Phenobarbital; Phenytoin; Valerates | 1998 |
Anticonvulsant drugs fail to modulate chemotherapy-induced cytotoxicity and growth inhibition of human malignant glioma cells.
Topics: Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cell Division; Cell Survival; Glioma; Humans; Osmolar Concentration; Phenytoin; Tumor Cells, Cultured; Valproic Acid | 1998 |
Treatment of the epileptic patient in the dental office.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Liability, Legal; Male; Medical History Taking; Middle Aged; Patient Care Planning; Phenobarbital; Phenytoin; Valproic Acid | 1998 |
Heart rate variability in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Female; Heart Rate; Humans; Male; Middle Aged; Phenytoin; Reference Values; Valproic Acid | 1998 |
Simultaneous determination of phenytoin, carbamazepine, and 10,11-carbamazepine epoxide in human plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenytoin; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1998 |
Rapid switchover to carbamazepine using pharmacokinetic parameters.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsies, Partial; Female; Humans; Male; Phenytoin; Pilot Projects; Primidone; Therapeutic Equivalency | 1998 |
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Acids; Dentate Gyrus; Epilepsy, Temporal Lobe; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Pyramidal Cells | 1998 |
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Female; Fetus; Heart; Humans; Hypoxia; Mice; Mice, Inbred C57BL; Phenobarbital; Phenytoin; Pregnancy; Rats; Trimethadione | 1998 |
The influence of L-NG-nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Drug Antagonism; Electroshock; Enzyme Inhibitors; Female; Memory; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1998 |
Medication and low serum thyroxine values in nursing home residents.
Topics: Aged; Aged, 80 and over; Carbamazepine; Euthyroid Sick Syndromes; Female; Frail Elderly; Homes for the Aged; Humans; Male; Nursing Homes; Phenytoin; Prednisone; Salicylates; Serum Albumin; Thyroid Function Tests; Thyrotropin; Thyroxine | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
Postmortem changes in blood concentrations of phenytoin and carbamazepine: an experimental study.
Topics: Animals; Anticonvulsants; Carbamazepine; Death, Sudden; Epilepsy; Humans; Phenytoin; Postmortem Changes; Rabbits; Sensitivity and Specificity; Treatment Refusal | 1998 |
Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine.
Topics: 5'-Nucleotidase; Animals; Anticonvulsants; Carbamazepine; Cells, Cultured; Cerebellum; Inositol; Lithium; Neuroprotective Agents; Phenytoin; Phosphatidylinositol 3-Kinases; Potassium; Rats; Rats, Sprague-Dawley | 1998 |
Frontal versus transcorneal stimulation to induce maximal electroshock seizures or kindling in mice and rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cornea; Differential Threshold; Electroshock; Female; Frontal Lobe; Kindling, Neurologic; Male; Mice; Phenytoin; Rats; Rats, Inbred Strains; Rats, Wistar; Seizures | 1998 |
Changes in arrhythmia profile and heart rate variability during abrupt withdrawal of antiepileptic drugs. Implications for sudden death.
Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Arrhythmias, Cardiac; Autonomic Nervous System; Carbamazepine; Death, Sudden, Cardiac; Epilepsy; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Substance Withdrawal Syndrome | 1997 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Autoantigens; Binding Sites; Carbamazepine; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA Primers; Epitope Mapping; Epitopes; HLA Antigens; Humans; Hypersensitivity; Intramolecular Oxidoreductases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenytoin; Rats; Thromboxane-A Synthase | 1998 |
Effects of lamotrigine and conventional antiepileptic drugs on amygdala- and hippocampal-kindled seizures in rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Triazines | 1998 |
Peripheral benzodiazepine receptor expression on leukocytes and neutrophil function during anticonvulsant monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Leukocytes; Lymphocytes; Male; Middle Aged; Neutrophils; Phenytoin; Receptors, GABA-A; Valproic Acid | 1998 |
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid | 1998 |
A common anticonvulsant binding site for phenytoin, carbamazepine, and lamotrigine in neuronal Na+ channels.
Topics: Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Carbamazepine; Kinetics; Lamotrigine; Neurons; Phenytoin; Rats; Rats, Long-Evans; Sodium Channel Blockers; Sodium Channels; Triazines | 1998 |
Antiepileptic drug use in nursing home residents: effect of age, gender, and comedication on patterns of use.
Topics: Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Utilization; Epilepsy; Female; Humans; Male; Medical Records Systems, Computerized; Nursing Homes; Phenytoin; Polypharmacy; Prevalence; Seizures; Sex Factors | 1998 |
Phenytoin, phenobarbital, and midazolam fail to stop status epilepticus-like activity induced by low magnesium in rat entorhinal slices, but can prevent its development.
Topics: Animals; Anticonvulsants; Carbamazepine; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Entorhinal Cortex; Magnesium; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Status Epilepticus | 1998 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dopamine; Dopamine Uptake Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium; Male; Norepinephrine; p-Chloroamphetamine; Phenytoin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Syndrome; Synaptosomes; Tetrodotoxin; Triazines; Valproic Acid; Zonisamide | 1998 |
Paroxysmal kinesigenic choreoathetosis in Singapore and its relationship to epilepsy.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Athetosis; Carbamazepine; Child; Chorea; Comorbidity; Diagnosis, Differential; Electroencephalography; Epilepsy; Family Characteristics; Female; Humans; Male; Phenytoin; Retrospective Studies; Seizures; Sex Distribution; White People | 1998 |
Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifibrinolytic Agents; Blood Coagulation; Carbamazepine; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrhage; Male; Mice; Mice, Inbred ICR; Partial Thromboplastin Time; Phenytoin; Piperidines; Prothrombin Time; Rifampin; Sulfonamides; Thromboembolism; Thromboplastin; Vitamin K 1; Warfarin | 1998 |
Carbamazepine-10,11-epoxide in therapeutic drug monitoring.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Humans; Lamotrigine; Phenytoin; Sodium Channels; Triazines; Valproic Acid | 1998 |
Clinical manifestations of 20 Taiwanese patients with paroxysmal kinesigenic dyskinesia.
Topics: Adolescent; Carbamazepine; Child; Cohort Studies; Female; Humans; Male; Movement Disorders; Pedigree; Phenytoin; Prognosis; Retrospective Studies; Taiwan; Treatment Outcome | 1998 |
[Serum lipids. lipoproteins, and apolipoproteins in adult epileptics treated with carbamazepine, valproic acid, or phenytoin].
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Apolipoproteins; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Enzyme Activation; Epilepsy; Female; Humans; Hyperlipidemias; Lipids; Lipoproteins; Male; Middle Aged; Phenytoin; Sex Characteristics; Triglycerides; Valproic Acid | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glioma; Humans; Magnetic Resonance Imaging; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Phenytoin; Temporal Lobe; Tomography, Emission-Computed, Single-Photon; Valproic Acid; Vigabatrin | 1998 |
Comparison between premortem and postmortem serum concentrations of phenobarbital, phenytoin, carbamazepine and its 10,11-epoxide metabolite in institutionalized patients with epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postmortem Changes; Time Factors | 1999 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Anticonvulsant and neurotoxic effects of intracerebroventricular injection of phenytoin, phenobarbital and carbamazepine in an amygdala-kindling model of epilepsy in the rat.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Injections, Intraventricular; Kindling, Neurologic; Male; Nervous System; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Time Factors | 1999 |
Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha).
Topics: 4-Aminopyridine; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Neuroprotective Agents; Phenytoin; Potassium Channel Blockers; Scorpion Venoms; Seizures | 1999 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Assessment of colour vision in epileptic patients exposed to single-drug therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Color Perception; Color Vision Defects; Diplopia; Epilepsy, Complex Partial; Female; Humans; Male; Middle Aged; Phenytoin; Severity of Illness Index; Single-Blind Method; Valproic Acid | 1999 |
Successful treatment with gabapentin in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Hypersensitivity; Drug Interactions; Epilepsy, Complex Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenytoin; Valproic Acid | 1999 |
Effect of heating human sera at a temperature necessary to deactivate human immunodeficiency virus on measurement of free phenytoin, free valproic acid, and free carbamazepine concentrations.
Topics: Anticonvulsants; Blood; Carbamazepine; Hemofiltration; HIV; Hot Temperature; Humans; Phenytoin; Valproic Acid; Virus Activation | 1999 |
Free drug measurements. When and why? An overview.
Topics: Biological Availability; Carbamazepine; Digoxin; Pharmaceutical Preparations; Pharmacokinetics; Phenytoin; Protein Binding; Temperature; Valproic Acid | 1999 |
Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus.
Topics: Animals; Anticonvulsants; Benzamides; Benzopyrans; Carbamazepine; Cells, Cultured; Embryo, Mammalian; Hippocampus; Lamotrigine; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenytoin; Rats; Sodium Channel Blockers; Sodium Channels; Triazines | 1999 |
Malformations in offspring of women with epilepsy: a prospective study.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Comorbidity; Congenital Abnormalities; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Gestational Age; Humans; Incidence; Infant, Newborn; Italy; Male; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications; Prospective Studies; Risk Factors; Valproic Acid | 1999 |
Problem of managing patients with epilepsy in developing countries.
Topics: Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Developing Countries; Drug Costs; Economics, Pharmaceutical; Epilepsy; Humans; India; Phenytoin; Research Design; Treatment Outcome; United States | 1999 |
Clinical experience with new antiepileptic drugs: antiepileptic drugs in Europe.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cross-Cultural Comparison; Drug Approval; Drug Monitoring; Drug Prescriptions; Epilepsy; Europe; History, 20th Century; Humans; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures.
Topics: Acetates; Alanine; Amines; Amygdala; Animals; Anticonvulsants; Behavior, Animal; Benzylamines; Carbamazepine; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Complex Partial; Gabapentin; gamma-Aminobutyric Acid; Kindling, Neurologic; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Triazines | 1999 |
Late radiation toxicity after whole brain radiotherapy: the influence of antiepileptic drugs.
Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Analysis of Variance; Anticonvulsants; Atrophy; Barbiturates; Brain; Brain Neoplasms; Carbamazepine; Cranial Irradiation; Dose Fractionation, Radiation; Female; Follow-Up Studies; Forecasting; Humans; Linear Models; Lymphoma; Male; Middle Aged; Multivariate Analysis; Neurologic Examination; Neuroprotective Agents; Phenytoin; Retrospective Studies; Tomography, X-Ray Computed | 1999 |
Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Infusions, Intravenous; Lomustine; Male; Middle Aged; Mixed Function Oxygenases; Phenytoin; Procarbazine; Vincristine | 1999 |
Anticonvulsant-induced toxic epidermal necrolysis: monitoring the immunologic response.
Topics: Adult; Antibody Formation; Anticonvulsants; Blood Cells; Carbamazepine; CD3 Complex; Cytokines; E-Selectin; Endothelium; Female; Humans; Male; Middle Aged; Phenytoin; Receptors, Lymphocyte Homing; Skin; Stevens-Johnson Syndrome | 2000 |
Possible analgesic effect of vigabatrin in animal experimental chronic neuropathic pain.
Topics: Analgesics; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Neuralgia; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1999 |
Blockade of neuronal sodium channels by the antiepileptic drugs phenytoin, carbamazepine and sodium valproate.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Membrane Potentials; Neurons; Oocytes; Patch-Clamp Techniques; Phenytoin; Sodium Channel Blockers; Sodium Channels; Valproic Acid; Xenopus laevis | 1999 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Onset and duration of action of rocuronium in children receiving chronic anticonvulsant therapy.
Topics: Analysis of Variance; Androstanols; Anesthesia Recovery Period; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Drug Interactions; Electric Stimulation; Electromyography; Epilepsy; Evoked Potentials, Motor; Humans; Injections, Intravenous; Muscle Contraction; Muscle, Skeletal; Neuromuscular Blockade; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Phenytoin; Rocuronium; Synaptic Transmission; Thumb; Time Factors | 2000 |
Long-term anticonvulsant therapy leads to low bone mineral density--evidence for direct drug effects of phenytoin and carbamazepine on human osteoblast-like cells.
Topics: Absorptiometry, Photon; Adult; Amino Acids; Anticonvulsants; Bone Density; Bone Resorption; Carbamazepine; Cell Division; Female; Humans; Male; Middle Aged; Osteoblasts; Osteocalcin; Osteoporosis; Phenytoin | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Changes in bone turnover and deoxypyridinoline levels in epileptic patients.
Topics: Adult; Alkaline Phosphatase; Amino Acids; Anticonvulsants; Bone and Bones; Calcium; Carbamazepine; Case-Control Studies; Epilepsy; Female; Humans; Male; Osteocalcin; Phenobarbital; Phenytoin; Sex Factors; Vitamin D | 2000 |
[Drug resistant epilepsy in Senegal: therapeutic, clinical and socioeconomic factors].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Senegal; Socioeconomic Factors; Valproic Acid | 1999 |
Plasma total glutathione concentrations in epileptic patients taking anticonvulsants.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cysteine; Epilepsy; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Phenytoin | 2000 |
A clinical study of 57 children with fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Fetal Diseases; Humans; Infant; Male; Phenotype; Phenytoin; Pregnancy; Syndrome; Valproic Acid | 2000 |
Refractory idiopathic absence status epilepticus: A probable paradoxical effect of phenytoin and carbamazepine.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Female; Humans; Male; Middle Aged; Phenytoin; Status Epilepticus; Treatment Outcome | 2000 |
Phenytoin poisoning after using Chinese proprietary medicines.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Combinations; Drug Contamination; Drugs, Chinese Herbal; Female; Humans; Phenytoin; Valproic Acid | 2000 |
Do carbamazepine and phenytoin aggravate juvenile myoclonic epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Child; Female; Humans; Male; Myoclonic Epilepsy, Juvenile; Phenytoin; Retrospective Studies | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Female; Hospital Units; Humans; Length of Stay; Male; Middle Aged; Monitoring, Physiologic; Phenytoin; Substance Withdrawal Syndrome; Valproic Acid; Videotape Recording | 2001 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnormalities; Epilepsy; Face; Female; Fetal Growth Retardation; Fingers; Humans; Infant, Newborn; Logistic Models; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2001 |
The concentration of three anti-seizure medications in hair: the effects of hair color, controlling for dose and age.
Topics: Age Factors; Anticonvulsants; Carbamazepine; Hair; Hair Color; Humans; Phenytoin; Valproic Acid | 2001 |
Do antiepileptics phenytoin, carbamazepine, and loreclezole show GABA(A) receptor subtype selectivity in rat brain sections?
Topics: Animals; Anticonvulsants; Autoradiography; Brain; Bridged Bicyclo Compounds, Heterocyclic; Carbamazepine; In Vitro Techniques; Male; Phenytoin; Protein Isoforms; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles | 2001 |
Protease inhibitors and anticonvulsants.
Topics: Anti-HIV Agents; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Isoenzymes; Phenobarbital; Phenytoin | 1997 |
The effects of carbamazepine on an appetitive-to-aversive transfer task: comparison to untreated and phenytoin.
Topics: Animals; Anticonvulsants; Appetitive Behavior; Avoidance Learning; Carbamazepine; Female; Phenytoin; Rats; Rats, Sprague-Dawley; Transfer, Psychology | 2001 |
Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cohort Studies; Death, Sudden; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Registries; Regression Analysis; Risk; Risk Factors; Sweden; Valproic Acid | 2001 |
Rapacuronium administration to patients receiving phenytoin or carbamazepine.
Topics: Adult; Anticonvulsants; Brain Injuries; Brain Neoplasms; Carbamazepine; Craniotomy; Drug Interactions; Humans; Intracranial Hypertension; Male; Monitoring, Intraoperative; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Phenytoin; Synaptic Transmission; Time Factors; Vecuronium Bromide | 2001 |
Induction of hypersensitivity to a previously tolerated antiepileptic drug by a second antiepileptic drug.
Topics: Adult; Anticonvulsants; Carbamazepine; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Humans; Male; Pharmacogenetics; Phenytoin | 2001 |
Course of chronic focal epilepsy resistant to anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Cluster Analysis; Disease Progression; Documentation; Drug Administration Schedule; Drug Resistance; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Male; Periodicity; Phenobarbital; Phenytoin | 2001 |
Drug interactions with selective serotonin reuptake inhibitors, especially with other psychotropics.
Topics: Anticoagulants; Anticonvulsants; Antidepressive Agents, Second-Generation; Carbamazepine; Contraindications; Drug Interactions; Fluoxetine; Humans; Monoamine Oxidase Inhibitors; Phenytoin; Selective Serotonin Reuptake Inhibitors | 2001 |
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.
Topics: Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Cell Line; Cholagogues and Choleretics; Cholesterol; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Humans; Hydroxycholesterols; Insecta; Kinetics; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Recombinant Proteins; Ursodeoxycholic Acid | 2001 |
Pharmacokinetics and pharmacodynamics of vecuronium in children receiving phenytoin or carbamazepine for chronic anticonvulsant therapy.
Topics: Adolescent; Anesthesia, General; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Resistance; Electromyography; Female; Half-Life; Humans; Male; Neuromuscular Junction; Neuromuscular Nondepolarizing Agents; Orosomucoid; Phenytoin; Vecuronium Bromide | 2001 |
[Analogs of generic preparations for the treatment of epilepsy: is their use safe?].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drugs, Generic; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenytoin; Therapeutic Equivalency; Valproic Acid | 2001 |
Timely antemortem and postmortem concentrations in a fatal carbamazepine overdose.
Topics: Absorption; Adult; Amobarbital; Anticonvulsants; Carbamazepine; Drug Overdose; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Phenytoin; Status Epilepticus | 2001 |
Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; GABA Antagonists; Hippocampus; Male; Neurons; Phenytoin; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley | 2002 |
[Refractory arterial hypertension and the use of anticonvulsant drugs. Case report].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hypertension; Male; Phenytoin | 2001 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Seizures, Febrile; Time Factors; Valproic Acid | 2002 |
Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes.
Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Lamotrigine; Male; Phenethylamines; Phenytoin; Rats; Rats, Wistar; Sodium; Sodium Channels; Synaptosomes; Tetrodotoxin; Triazines; Veratridine | 2002 |
Significant reduction of sertraline plasma levels by carbamazepine and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Phenytoin; Selective Serotonin Reuptake Inhibitors; Sertraline | 2002 |
Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder.
Topics: Administration, Oral; Animals; Anticonvulsants; Bipolar Disorder; Brain; Carbamazepine; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Fructose; Hyperkinesis; Motor Activity; Neurons; Phenytoin; Quinpirole; Rats; Receptors, Dopamine; Topiramate; Valproic Acid | 2002 |
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Eye Abnormalities; Female; Fetal Diseases; Humans; Infant; Male; Phenytoin; Prevalence; Refractive Errors; Retrospective Studies; Strabismus; Syndrome; Valproic Acid; Visual Acuity | 2002 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum.
Topics: Anticonvulsants; Automation; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization; Humans; Phenobarbital; Phenytoin; Reproducibility of Results; Valproic Acid | 2002 |
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Hypersensitivity; Eosinophilia; Humans; Male; Phenobarbital; Phenytoin | 2002 |
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitoring; Humans; Immunoassay; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Uremia; Valproic Acid | 2002 |
Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Epilepsy; Female; Follow-Up Studies; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors | 2002 |
In vitro removal of therapeutic drugs with a novel adsorbent system.
Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; Hemoperfusion; Humans; Models, Biological; Phenobarbital; Phenytoin; Sorption Detoxification; Theophylline; Uremia; Valproic Acid | 2002 |
Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ion Channel Gating; Lamotrigine; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sodium Channels; Triazines; Valproic Acid | 2002 |
Chondrodysplasia punctata (CDP) with features of the tibia-metacarpal type and maternal phenytoin treatment during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Chondrodysplasia Punctata; Craniofacial Abnormalities; Epilepsy; Female; Fetal Growth Retardation; Humans; Male; Maternal-Fetal Exchange; Metacarpus; Phenytoin; Pregnancy; Pregnancy Complications; Radiography; Tibia; Ultrasonography | 2002 |
Therapeutic drug monitoring of anticonvulsant drugs by micellar HPLC with direct injection of serum samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Micelles; Phenobarbital; Phenytoin | 2002 |
Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Bicuculline; Carbamazepine; Ceftizoxime; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, GABA; Seizures; Sodium Channel Blockers | 2002 |
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chlorophyll; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Mephenytoin; Microsomes; Mixed Function Oxygenases; Oxcarbazepine; Phenytoin; Recombinant Proteins | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Paroxysmal dyskinesia in phenytoin toxicity.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Chorea; Female; Humans; Phenytoin; Seizures | 2002 |
Therapeutic monitoring of digoxin and antiepileptic drugs in Egypt and Saudi Arabia.
Topics: Anticonvulsants; Carbamazepine; Cardiotonic Agents; Developing Countries; Digoxin; Drug Monitoring; Egypt; Humans; Phenytoin; Retrospective Studies; Saudi Arabia; Valproic Acid | 2003 |
Evaluation of therapeutic drug monitoring of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Hospitals, Teaching; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 2003 |
Valproate overdose: a comparative cohort study of self poisonings.
Topics: Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Cohort Studies; Critical Care; Drug Overdose; Drug Prescriptions; Female; Humans; Male; New South Wales; Phenytoin; Prospective Studies; Valproic Acid | 2003 |
Expression of the POU domain transcription factor, Oct-6, is attenuated in the adult mouse telencephalon, but increased by neurotoxic damage.
Topics: Age Factors; Animals; Anticonvulsants; Blotting, Western; Carbamazepine; Chelating Agents; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Immunohistochemistry; In Situ Hybridization; Male; Octamer Transcription Factor-6; Phenytoin; Rats; Reverse Transcriptase Polymerase Chain Reaction; Telencephalon; Transcription Factors | 2003 |
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Female; Gambia; Humans; Infant; Learning Disabilities; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Psychomotor Disorders; Seizures; Treatment Outcome | 2003 |
Potent analgesic effects of anticonvulsants on peripheral thermal nociception in rats.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Calcium Channel Blockers; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Female; Gabapentin; gamma-Aminobutyric Acid; Hindlimb; Hyperalgesia; Neurons, Afferent; Pain Measurement; Peripheral Nervous System Diseases; Phenytoin; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers | 2003 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.
Topics: 4-Aminopyridine; Animals; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; Injections; Male; Phenytoin; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 2003 |
Validated high performance liquid chromatographic method for simultaneous determination of phenytoin, phenobarbital and carbamazepine in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Spotlight on oxcarbazepine in epilepsy.
Topics: Adolescent; Anticonvulsants; Area Under Curve; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Cytochromes; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Epilepsy; Female; Humans; Male; Oxcarbazepine; Phenytoin | 2004 |
Appropriateness of serum level determinations of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Monitoring; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 2003 |
L-histidine is a beneficial adjuvant for antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Histidine; Mice; Phenytoin; Seizures | 2004 |
Cost of epilepsy in patients attending a secondary-level hospital in India.
Topics: Anticonvulsants; Carbamazepine; Efficiency, Organizational; Epilepsy; Hospital Costs; Hospitalization; Humans; India; Phenobarbital; Phenytoin; Valproic Acid | 2004 |
The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides; Valproic Acid | 2004 |
Modulation of antiepileptic effect of phenytoin and carbamazepine by melatonin in mice.
Topics: Animals; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy; Forecasting; Injections, Intraperitoneal; Male; Melatonin; Mice; Phenytoin | 2004 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
Frontal lobe seizures and uveitis associated with acute human parvovirus B19 infection.
Topics: Acute Disease; Anti-Inflammatory Agents; Anticonvulsants; Brain; Carbamazepine; Child, Preschool; Electroencephalography; Erythema Infectiosum; Female; Frontal Lobe; Humans; Lamotrigine; Magnetic Resonance Imaging; Ophthalmic Solutions; Parvovirus B19, Human; Phenytoin; Polymerase Chain Reaction; Prednisone; Seizures; Triazines; Uveitis; Video Recording | 2004 |
Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs.
Topics: 3-O-Methylglucose; Amitriptyline; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Carbamazepine; Cell Line, Tumor; Humans; Immunohistochemistry; Monoamine Oxidase Inhibitors; Monosaccharide Transport Proteins; Neuroglia; Neurons; Phenytoin; Selegiline | 2004 |
Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Estradiol; Humans; Lamotrigine; Luteinizing Hormone; Male; Middle Aged; Phenytoin; Sex Hormone-Binding Globulin; Sexual Behavior; Surveys and Questionnaires; Testosterone; Triazines | 2004 |
[Nonconvulsion epileptic encepholopathies and their treatment].
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Severity of Illness Index; Tomography, X-Ray Computed | 2004 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pyridoxal Phosphate; Sensitivity and Specificity; Transaminases; Valproic Acid | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
Simple and rapid micellar electrokinetic capillary chromatographic method for simultaneous determination of four antiepileptics in human serum.
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Ethosuximide; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Phenytoin; Primidone; Quality Control; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2004 |
The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey.
Topics: Aged; Anticonvulsants; Carbamazepine; Child, Preschool; Clinical Competence; Epilepsy; Family Practice; Female; Humans; Lamotrigine; Male; Phenytoin; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil.
Topics: Adult; Anticonvulsants; Brazil; Carbamazepine; Epilepsy; Health Services Accessibility; Health Services Needs and Demand; Humans; Phenobarbital; Phenytoin; Prevalence; Valproic Acid | 2004 |
Longer term outcome of children born to mothers with epilepsy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Multivariate Analysis; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Valproic Acid | 2004 |
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid | 2004 |
Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Isoenzymes; Male; Phenobarbital; Phenytoin | 2004 |
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Influence of high fat diet (butter) on pharmacokinetics of phenytoin and carbamazepine.
Topics: Absorption; Animals; Anticonvulsants; Area Under Curve; Biological Availability; Butter; Carbamazepine; Cross-Over Studies; Food-Drug Interactions; Male; Phenytoin; Rabbits | 2004 |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facies; Female; Fingers; Follow-Up Studies; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Toes | 2005 |
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Central Nervous System Agents; Colloids; Drug Overdose; Female; Follow-Up Studies; Gastric Emptying; Gastrointestinal Motility; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Stomach; Technetium Compounds; Tin Compounds | 2004 |
Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Bone and Bones; Bone Remodeling; Carbamazepine; Epilepsy; Female; Humans; Minerals; Phenytoin; Premenopause; Valproic Acid | 2005 |
Cisatracurium-induced neuromuscular blockade is affected by chronic phenytoin or carbamazepine treatment in neurosurgical patients.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anticonvulsants; Atracurium; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Electric Stimulation; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Monitoring, Intraoperative; Nerve Block; Neuromuscular Nondepolarizing Agents; Neurosurgical Procedures; Phenytoin; Synaptic Transmission | 2005 |
Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis.
Topics: Aged; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Heart Failure; Humans; Myocarditis; Phenytoin | 2005 |
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study.
Topics: Adult; Allopurinol; Analgesics, Non-Narcotic; Anticonvulsants; Antimetabolites; Carbamazepine; Case-Control Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Phenytoin; Risk Assessment; Stevens-Johnson Syndrome; Taiwan | 2005 |
Lamotrigine, carbamazepine and phenytoin differentially alter extracellular levels of 5-hydroxytryptamine, dopamine and amino acids.
Topics: Amino Acids; Animals; Anticonvulsants; Carbamazepine; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Hippocampus; Lamotrigine; Male; Phenytoin; Rats; Rats, Wistar; Serotonin; Time Factors; Triazines | 2005 |
Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin.
Topics: Adolescent; Adult; Aged; Alleles; Amino Acid Sequence; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Base Sequence; Brain; Carbamazepine; Child; Child, Preschool; Cohort Studies; Cytochrome P-450 CYP2C9; Epilepsy; Exons; Female; Genetic Markers; Genotype; Humans; Infant; Introns; Male; Middle Aged; Molecular Sequence Data; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Phenytoin; Polymorphism, Genetic; Sodium Channels | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Gene variants affect response to antiepileptic drugs.
Topics: Alternative Splicing; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Drug Resistance; Epilepsy; Exons; Genetic Variation; Humans; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Phenytoin; Polymorphism, Genetic; Sodium Channels | 2005 |
Gene variants explain patient differences in antiepileptic drug responses.
Topics: Anticonvulsants; Carbamazepine; Humans; Pharmacogenetics; Phenytoin | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Triazines | 2005 |
Influence of aminoglutethimide and spironolactone on the efficacy of carbamazepine and diphenylhydantoin against amygdala-kindled seizures in rats.
Topics: Aminoglutethimide; Amygdala; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Therapy, Combination; Female; Hydrocortisone; Kindling, Neurologic; Male; Motor Activity; Phenytoin; Rats; Rats, Wistar; Rotarod Performance Test; Seizures; Spironolactone | 2005 |
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells.
Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carbamazepine; Cattle; Cell Separation; Cells, Cultured; Cerebral Cortex; Clozapine; Endothelial Cells; Hydrocortisone; Paroxetine; Phenytoin; Rats; Retina; Selective Serotonin Reuptake Inhibitors | 2005 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Middle Aged; Phenytoin; Treatment Outcome | 2005 |
Cross Hypersensitivity Syndrome between Phenytoin and Carbamazepine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Drug Hypersensitivity; Female; Humans; Infant; Male; Middle Aged; Phenytoin; Retrospective Studies | 2005 |
An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.
Topics: Amphetamine; Anesthetics, Dissociative; Animals; Antimanic Agents; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Ketamine; Lithium; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenytoin; Reflex, Startle; Valproic Acid | 2005 |
Influence of LY 300164 alone or in combination with carbamazepine or diphenylhydantoin on the body temperature in mice.
Topics: Animals; Anticonvulsants; Benzodiazepines; Body Temperature; Carbamazepine; Female; Mice; Phenytoin; Receptors, AMPA | 2004 |
Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Pregabalin; Triazines; Valproic Acid | 2005 |
1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Electroshock; Male; Mice; Neurotoxicity Syndromes; Phenytoin; Tetrahydroisoquinolines; Valproic Acid | 2006 |
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Topiramate; Valproic Acid | 2005 |
Mathematical representation of analyte's capacity factor in binary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2005 |
2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Glutamate Carboxypeptidase II; Male; Mice; Organophosphorus Compounds; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2006 |
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Pyridoxal Phosphate; Reference Values; Valproic Acid; Vitamin B 12 | 2006 |
Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Fluoresceins; Fluorescent Dyes; Humans; Hypersensitivity, Delayed; Lymphocyte Activation; Male; Middle Aged; Phenytoin; Succinimides; T-Lymphocytes; Tetanus Toxoid | 2006 |
Transient occipitotemporal subcortical diffusion-weighted magnetic resonance imaging abnormalities associated with status epilepticus. Case report.
Topics: Adult; Carbamazepine; Diazepam; Diffusion Magnetic Resonance Imaging; Drug Administration Schedule; Electroencephalography; Humans; Injections, Intramuscular; Male; Occipital Lobe; Phenytoin; Severity of Illness Index; Status Epilepticus; Temporal Lobe; Time Factors; Valproic Acid | 2006 |
Correlation of retention factor of analytes in quaternary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Carbamazepine; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2006 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazepam; Epilepsy; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2006 |
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones | 2006 |
Drug hypersensitivity to previously tolerated phenytoin by carbamazepine-induced DRESS syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Phenytoin; Skin; Syndrome | 2006 |
Phenytoin-induced DRESS with cross-reactivity to carbamazepine in a 10-year-old Indian child.
Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Child; Drug Eruptions; Eosinophilia; Epilepsy; Glucocorticoids; Humans; Male; Phenytoin; Prednisolone; Treatment Outcome | 2006 |
Response to Zhou et al. Osteomalacia is a frequent complication resulting from long-term therapy with drugs such as phenytoin, carbamazepine, and phenobarbital.
Topics: Anticonvulsants; Carbamazepine; Constitutive Androstane Receptor; Gene Expression; Humans; Osteomalacia; Phenobarbital; Phenytoin; Pregnane X Receptor; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Steroid Hydroxylases; Transcription Factors; Vitamin D3 24-Hydroxylase | 2006 |
Antiepileptic TDM pattern at a tertiary care hospital in India.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; India; Pharmacology, Clinical; Pharmacy Service, Hospital; Phenobarbital; Phenytoin; Retrospective Studies | 2006 |
Phenytoin and carbamazepine delay the initial depression of the population spike upon exposure to in vitro ischemia and promote its post-ischemic functional recovery in rat hippocampal slices.
Topics: Animals; Anticonvulsants; Brain Ischemia; Carbamazepine; Electrophysiology; Glucose; Hippocampus; Hypoxia-Ischemia, Brain; In Vitro Techniques; Membrane Potentials; Neuroprotective Agents; Phenytoin; Rats; Rats, Wistar; Receptors, Presynaptic | 2006 |
Differential effects of antiepileptic drugs on neuroactive steroids in men with epilepsy.
Topics: Adolescent; Adult; Androgens; Androstanes; Anticonvulsants; Biological Availability; Carbamazepine; Dehydroepiandrosterone; Enzyme Induction; Epilepsies, Partial; Estradiol; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Sexual Dysfunctions, Psychological; Steroids; Testosterone; Triazines | 2006 |
Epilepsy, parkinsonism, and neuroleptic malignant syndrome in a child.
Topics: Anticonvulsants; Antiparkinson Agents; Aspartic Acid; Basal Ganglia; Benzothiazoles; Carbamazepine; Child; Electroencephalography; Epilepsy; Epilepsy, Complex Partial; Female; Humans; Magnetic Resonance Spectroscopy; Neuroleptic Malignant Syndrome; Parkinsonian Disorders; Phenytoin; Pramipexole; Time | 2006 |
Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Auditory Pathways; Auditory Perception; Auditory Threshold; Brain Stem; Carbamazepine; Electrophysiology; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Male; Neural Conduction; Phenytoin; Reaction Time; Valproic Acid; Vinca Alkaloids | 2007 |
Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Benzodiazepines; Carbamazepine; Cross Reactions; Cyclohexanecarboxylic Acids; Doxepin; Drug Hypersensitivity; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Molecular Structure; Phenytoin; Skin Tests; Syndrome; Valproic Acid | 2006 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Superior oblique myokymia: efficacy of medical treatment.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Diplopia; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Optical Illusions; Phenytoin; Propranolol; Retrospective Studies; Treatment Outcome; Trochlear Nerve Diseases; Valproic Acid | 2007 |
Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Iran; Male; Middle Aged; Phenobarbital; Phenytoin | 2007 |
Drug treatment during pregnancy and isolated orofacial clefts in hungary.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Antagonists; Amoxicillin; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Case-Control Studies; Cleft Lip; Cleft Palate; Dopamine Antagonists; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hungary; Oxprenolol; Oxytetracycline; Phenytoin; Population Surveillance; Pregnancy; Pregnancy Trimesters; Prospective Studies; Retrospective Studies; Risk Factors; Thiethylperazine | 2007 |
Intestinal expression of cytochrome P450 enzymes and ABC transporters and carbamazepine and phenytoin disposition.
Topics: Adult; Aged; Anticonvulsants; ATP-Binding Cassette Transporters; Carbamazepine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Duodenum; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Polymorphism, Genetic | 2007 |
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro.
Topics: Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Count; Dose-Response Relationship, Drug; Drug Resistance; Electrophysiology; Entorhinal Cortex; Epilepsy, Temporal Lobe; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Male; Nerve Net; Phenylenediamines; Phenytoin; Rats; Rats, Sprague-Dawley | 2007 |
Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ecto-nucleotidases.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebral Cortex; Epilepsy; Hippocampus; Male; Muscarinic Agonists; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Synaptosomes; Valproic Acid | 2007 |
Effects of phenytoin and carbamazepine on calcium transport in Caco-2 cells.
Topics: Amines; Anticonvulsants; Biological Transport, Active; Bone Diseases; Caco-2 Cells; Calcium; Carbamazepine; Cell Membrane Permeability; Cyclohexanecarboxylic Acids; Epithelial Cells; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenytoin; Topiramate; Vitamin D | 2007 |
Factors affecting antiepileptic drug pharmacokinetics in community-dwelling elderly.
Topics: Absorption; Adult; Aged; Aged, 80 and over; Aging; Anticonvulsants; Biological Availability; Carbamazepine; Female; Half-Life; Humans; Male; Middle Aged; Phenytoin | 2007 |
Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy.
Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Carbamazepine; Drug Resistance, Multiple; Epilepsy; Fluorescent Antibody Technique; Genetic Predisposition to Disease; Genetic Variation; Genotype; GTPase-Activating Proteins; Haplotypes; Humans; Immunohistochemistry; Multidrug Resistance-Associated Proteins; Pharmacogenetics; Phenotype; Phenytoin; Polymorphism, Single Nucleotide | 2007 |
Diminished response of CA1 neurons to antiepileptic drugs in chronic epilepsy.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Chronic Disease; Dentate Gyrus; Disease Models, Animal; Drug Resistance; Epilepsy; Hippocampus; Humans; Neurons; Patch-Clamp Techniques; Phenytoin; Pilocarpine; Pyramidal Cells; Rats; Sodium Channels; Synaptic Transmission | 2007 |
An ImmunoChip prototype for simultaneous detection of antiepileptic drugs using an enhanced one-step homogeneous immunoassay.
Topics: Anticonvulsants; Carbamazepine; Humans; Immunoassay; Phenytoin; Reagent Kits, Diagnostic; Sensitivity and Specificity; Valproic Acid | 2007 |
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electromyography; Electroshock; Ethosuximide; Fructose; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors; Topiramate | 2007 |
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Drug Synergism; Electroshock; Fluoxetine; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2007 |
Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Furans; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Valproic Acid | 2007 |
Rash from antiepileptic drugs: influence by gender, age, and learning disability.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Comorbidity; Drug Eruptions; Epilepsy; Female; Humans; Hygiene; Incidence; Lamotrigine; Learning Disabilities; Male; Phenytoin; Retrospective Studies; Risk Factors; Sex Factors; Triazines | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Female; Genetic Predisposition to Disease; HLA-B Antigens; HLA-B15 Antigen; Hong Kong; Humans; Lamotrigine; Male; Middle Aged; Pharmacogenetics; Phenytoin; Polymorphism, Genetic; Stevens-Johnson Syndrome; Triazines | 2007 |
Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Acetamides; Algorithms; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Epilepsy; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Motor Skills; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Cholecalciferol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Injections, Intraperitoneal; Male; Mental Recall; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Vitamins | 2007 |
Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electroshock; Fluorescent Antibody Technique; Male; Memory; Mianserin; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Exacerbation of experimental autoimmune encephalomyelitis after withdrawal of phenytoin and carbamazepine.
Topics: Animals; Anticonvulsants; Antigens, CD; Axons; Carbamazepine; Cell Count; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Gene Expression Regulation; Glycoproteins; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; NAV1.6 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Peptide Fragments; Phenytoin; Pyramidal Tracts; Severity of Illness Index; Sodium Channels; Substance Withdrawal Syndrome | 2007 |
Screening for the effects of antiepileptic drugs on short term plasticity using a time efficient bioassay.
Topics: Animals; Anticonvulsants; Biological Assay; Carbamazepine; Electrophysiology; Equipment Design; Hippocampus; Male; Models, Statistical; Neuronal Plasticity; Phenytoin; Poisson Distribution; Rats; Time Factors; Valproic Acid | 2007 |
Pharmacokinetics of midazolam and metabolites in a patient with refractory status epilepticus treated with extraordinary doses of midazolam.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Half-Life; Humans; Metabolic Clearance Rate; Midazolam; Middle Aged; Phenytoin; Status Epilepticus | 2008 |
Temporal pattern of oxcarbazepine and phenytoin withdrawal seizures during epilepsy monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Electroencephalography; Epilepsy; Female; Humans; Male; Monitoring, Physiologic; Oxcarbazepine; Phenytoin; Poisson Distribution; Retrospective Studies; Seizures; Substance Withdrawal Syndrome | 2008 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
Aromatic antiepileptic drugs and mitochondrial toxicity: effects on mitochondria isolated from rat liver.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Calcium; Calcium Signaling; Carbamazepine; Dose-Response Relationship, Drug; Male; Membrane Potential, Mitochondrial; Microsomes, Liver; Mitochondria, Liver; Mitochondrial Swelling; Oxygen Consumption; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 2008 |
Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain.
Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Gene Expression; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley | 2008 |
Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium, Dietary; Carbamazepine; Collagen Type I; Epilepsy; Female; Femur; Humans; Lamotrigine; Life Style; Lumbar Vertebrae; Minerals; Parathyroid Hormone; Peptides; Phenytoin; Surveys and Questionnaires; Triazines; Valproic Acid; Vitamin D | 2008 |
Peroxidase-mediated bioactivation of hydroxylated metabolites of carbamazepine and phenytoin.
Topics: Animals; Anticonvulsants; Biotransformation; Carbamazepine; Cell Line; Chromatography, High Pressure Liquid; Dimerization; Horseradish Peroxidase; Hydroxylation; Magnetic Resonance Spectroscopy; Mice; Oxidative Stress; Peroxidase; Phenytoin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Sensitivity and Specificity | 2008 |
Association between SCN1A polymorphism and carbamazepine-resistant epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Genotype; Humans; Male; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Phenytoin; Polymorphism, Genetic; Sodium Channels; Treatment Outcome | 2008 |
Generalized tonic-clonic seizures after acute oxcarbazepine withdrawal.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenytoin; Seizures; Substance Withdrawal Syndrome | 2008 |
Changes in gene expression induced by carbamazepine and phenytoin: testing the danger hypothesis.
Topics: Animals; Anticonvulsants; Antigen-Presenting Cells; Biomarkers; Carbamazepine; Female; Free Radicals; Gene Expression Profiling; Gene Expression Regulation; Immune System Diseases; Mice; Oligonucleotide Array Sequence Analysis; Phenytoin; RNA, Messenger; Signal Transduction | 2008 |
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Genetic Predisposition to Disease; HLA-B Antigens; Humans; Male; Middle Aged; Pharmacogenetics; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; Thailand; Young Adult | 2008 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Characterization of phenytoin, carbamazepine, vinpocetine and clorgyline simultaneous effects on sodium channels and catecholamine metabolism in rat striatal nerve endings.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Aspartic Acid; Carbamazepine; Catecholamines; Clorgyline; Corpus Striatum; Dopamine; Glutamine; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Nerve Endings; Phenytoin; Rats; Rats, Wistar; Sodium Channel Agonists; Sodium Channels; Vinca Alkaloids | 2009 |
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.
Topics: Albumins; Animals; Carbamazepine; Cattle; Drug-Related Side Effects and Adverse Reactions; Hemodialysis Solutions; Humans; In Vitro Techniques; Models, Biological; Phenytoin; Poisoning; Protein Binding; Renal Dialysis; Valproic Acid | 2009 |
Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cardiolipins; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Sulfhydryl Compounds; Toxicity Tests | 2008 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Psychotic Disorders; Retrospective Studies; Sex Distribution; Suicide, Attempted; Triazines; Valproic Acid; Young Adult | 2009 |
FDA: Epilepsy drugs may carry skin risks for Asians.
Topics: Anticonvulsants; Asian People; Carbamazepine; HLA-B Antigens; Humans; Phenytoin; Risk; Skin Diseases; United States; United States Food and Drug Administration | 2008 |
Topiramate and zonisamide prevent paradoxical intoxication induced by carbamazepine and phenytoin.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Extracellular Fluid; Fructose; Hippocampus; Isoxazoles; Male; Movement; Neurotransmitter Agents; Phenytoin; Rats; Rats, Sprague-Dawley; Topiramate; Zonisamide | 2009 |
Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child, Preschool; Cognition; Developmental Disabilities; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Intelligence; Intelligence Tests; Lamotrigine; Neuropsychological Tests; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Regression Analysis; Triazines; Valproic Acid | 2009 |
Neuroprotective effects of diazepam, carbamazepine, phenytoin and ketamine after pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Carbamazepine; Dentate Gyrus; Diazepam; Drug Administration Schedule; Glial Fibrillary Acidic Protein; Hippocampus; Ketamine; Male; Maze Learning; Neuroprotective Agents; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus | 2009 |
N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Male; Memory; Mice; Models, Animal; Motor Activity; Muscle Strength; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2009 |
The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel.
Topics: Animals; Anticonvulsants; Binding Sites; Carbamazepine; Female; Ion Channel Gating; Lamotrigine; Models, Biological; Phenytoin; Point Mutation; Protein Structure, Tertiary; Rats; Sodium Channel Blockers; Sodium Channels; Triazines; Xenopus laevis | 2009 |
The use of antiepileptic drugs in pediatric brain tumor patients.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Child; Drug Interactions; Follow-Up Studies; Glioma; Humans; Levetiracetam; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Seizures; Supratentorial Neoplasms; Treatment Outcome | 2009 |
Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.
Topics: Adenosine; Algorithms; Animals; Anti-Inflammatory Agents; Anticonvulsants; Barbiturates; Carbamazepine; Central Nervous System Depressants; Convulsants; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Ethanol; Infusions, Intravenous; Lactones; Male; Mice; Pentylenetetrazole; Phenytoin; Plant Extracts; Seizures; Sulfones; Withania | 2009 |
Effect of pharmacist participation in the health care team on therapeutic drug monitoring utilization for antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Drug Monitoring; Epilepsy; Female; Humans; Male; Middle Aged; Patient Care Team; Pharmacists; Phenytoin; Valproic Acid | 2009 |
Valproic acid: long-term effects on children exposed in utero.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Female; Fructose; Humans; Intelligence; Lamotrigine; Language Development Disorders; Phenytoin; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Psychomotor Disorders; Topiramate; Triazines; Valproic Acid | 2009 |
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Drug Eruptions; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Patient Acceptance of Health Care; Phenytoin; Survival Analysis; Treatment Failure; Triazines; Valproic Acid; Young Adult | 2010 |
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Child; Drug-Related Side Effects and Adverse Reactions; Female; Genetic Association Studies; HLA Antigens; HLA-B Antigens; HLA-B15 Antigen; Humans; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacogenetics; Phenytoin; Risk Factors; Stevens-Johnson Syndrome; Taiwan; Triazines; Young Adult | 2010 |
In vitro effects of antiepileptic drugs on acetylcholinesterase and ectonucleotidase activities in zebrafish (Danio rerio) brain.
Topics: 5'-Nucleotidase; Acetylcholinesterase; Amines; Animals; Anticonvulsants; Brain; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapentin; gamma-Aminobutyric Acid; Phenytoin; Zebrafish | 2010 |
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy.
Topics: Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Resistance; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Treatment Outcome; Triazines | 2010 |
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Epilepsy; Female; Genotype; Humans; Male; Pharmacogenetics; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2010 |
Drug refractoriness of epileptiform activity in organotypic hippocampal slice cultures depends on the mode of provocation.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Electric Stimulation; Electrophysiology; Hippocampus; Neurons; Organ Culture Techniques; Phenytoin; Rats; Rats, Wistar | 2010 |
Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.
Topics: Adolescent; Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Case-Control Studies; Cytochrome P-450 CYP2C19; Epilepsy; Female; Gene Expression Profiling; Gene Frequency; Genotype; Humans; India; Male; Phenytoin; Polymorphism, Genetic; Young Adult | 2010 |
Effect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport.
Topics: Anticonvulsants; Carbamazepine; Folate Receptor 1; Humans; Phenytoin; Reactive Oxygen Species; RNA, Small Interfering; Tetrahydrofolates; Valproic Acid | 2010 |
A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes.
Topics: Biological Assay; Carbamazepine; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Cryopreservation; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Pharmaceutical Preparations; Phenytoin; Reverse Transcriptase Polymerase Chain Reaction; Rifampin | 2010 |
Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial; Female; Fructose; Humans; Kaplan-Meier Estimate; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2010 |
Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Muscle Strength; Muscle, Skeletal; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2010 |
Age and comedications influence levetiracetam pharmacokinetics in children.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Metabolic Clearance Rate; Oxcarbazepine; Phenytoin; Piracetam; Retrospective Studies; Triazines; Valproic Acid | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Synthesis and anticonvulsant activity of 7-alkoxy-triazolo-[3, 4-b]benzo[d]thiazoles.
Topics: Animals; Anticonvulsants; Benzothiazoles; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Mice; Motor Activity; Phenytoin; Seizures; Structure-Activity Relationship; Triazoles | 2010 |
Occurrence and removal of pharmaceuticals and hormones through drinking water treatment.
Topics: Atenolol; Carbamazepine; Hormones; Hydrochlorothiazide; Ozone; Pharmaceutical Preparations; Phenytoin; Sotalol; Water Pollutants, Chemical; Water Purification; Water Supply | 2011 |
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Cannabinoid Receptor Agonists; Carbamazepine; Drug Synergism; Electroshock; Male; Memory, Long-Term; Mice; Morpholines; Muscle Strength; Naphthalenes; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2011 |
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Exanthema; Female; Fever; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Risk Factors; Syndrome; Triazines; Young Adult | 2011 |
One-way multiplexed immunoassay strategy for simultaneous determination of multi-analytes by microchip electrophoresis.
Topics: Antibodies, Immobilized; Carbamazepine; Electrophoresis, Microchip; Glass; Humans; Immunoassay; Phenobarbital; Phenytoin; Sodium Dodecyl Sulfate; Theophylline | 2011 |
Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Encephalitis; Female; Humans; Intracellular Signaling Peptides and Proteins; Lamotrigine; Levetiracetam; Middle Aged; Phenytoin; Piracetam; Proteins; Seizures; Triazines | 2011 |
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.
Topics: Adolescent; Adult; Aged; Amines; Animals; Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Neocortex; Nipecotic Acids; Oximes; Phenytoin; Piracetam; Potassium; Pregabalin; Rats; Rats, Wistar; Synaptosomes; Tetanus Toxin; Tetrodotoxin; Triazines; Valproic Acid; Veratridine; Young Adult | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Curcumin; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Male; Maze Learning; Phenobarbital; Phenytoin; Random Allocation; Rats; Rats, Wistar; Valproic Acid | 2011 |
Normal vitamin D and low free estradiol levels in women on enzyme-inducing antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Bone Density; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Lamotrigine; Phenytoin; Triazines; Vitamin D | 2011 |
Trigeminal neuralgia: a retrospective study of 188 Thai cases.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Carbamazepine; Chronic Disease; Cryosurgery; Drug Therapy, Combination; Female; Humans; Incidence; Male; Mandibular Nerve; Mastication; Maxillary Nerve; Middle Aged; Muscle Relaxants, Central; Phenytoin; Retrospective Studies; Sex Factors; Speech; Thailand; Tooth; Tooth Extraction; Trigeminal Neuralgia; Young Adult | 2012 |
Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Calcium; Carbamazepine; Drug Interactions; Epilepsy; Fructose; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; In Vitro Techniques; Lamotrigine; Male; Nerve Endings; Oxcarbazepine; Phenytoin; Potassium Channel Blockers; Rats; Rats, Wistar; Sodium; Sodium Channel Blockers; Tetrodotoxin; Topiramate; Triazines; Tritium; Vinca Alkaloids | 2011 |
Procalcitonin, a high acute phase reactant in antiepileptic hypersentivity syndrome in pediatric age.
Topics: Adolescent; Anticonvulsants; Calcitonin; Calcitonin Gene-Related Peptide; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Epilepsy, Frontal Lobe; Epstein-Barr Virus Infections; Female; Humans; Male; Pentobarbital; Phenytoin; Protein Precursors; Transaminases | 2012 |
HLA-B*1502 screening and toxic effects of carbamazepine.
Topics: Anticonvulsants; Asian People; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; HLA-B Antigens; HLA-B15 Antigen; Humans; Phenytoin; Stevens-Johnson Syndrome | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
The interactions of atorvastatin and fluvastatin with carbamazepine, phenytoin and valproate in the mouse maximal electroshock seizure model.
Topics: Animals; Anticonvulsants; Atorvastatin; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Indoles; Male; Memory; Mice; Motor Activity; Phenytoin; Pyrroles; Seizures; Valproic Acid | 2012 |
Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Atherosclerosis; Blood Glucose; Carbamazepine; Carotid Artery, Common; Cross-Sectional Studies; Epilepsy; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Risk Factors; Time Factors; Uric Acid; Valproic Acid; Young Adult | 2012 |
Severe cutaneous adverse reactions to antiepileptic drugs in Asians.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Exanthema; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Middle Aged; Phenytoin; Retrospective Studies; Risk Factors; Severity of Illness Index; Stevens-Johnson Syndrome; Taiwan; Triazines | 2011 |
Conversion from enzyme-inducing antiepileptic drugs to topiramate: effects on lipids and C-reactive protein.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; C-Reactive Protein; Carbamazepine; Epilepsy; Female; Fructose; Humans; Lipids; Lipoproteins, LDL; Male; Middle Aged; Phenytoin; Topiramate | 2012 |
Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.
Topics: Adult; Aged; Aged, 80 and over; Amines; Amitriptyline; Analgesics; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Pain Measurement; Phenytoin; Retrospective Studies; Sri Lanka; Treatment Outcome; Trigeminal Neuralgia; Valproic Acid | 2012 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet | 2012 |
Drug-induced pemphigus after six years of treatment with phenytoin and carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Middle Aged; Multiple Sclerosis; Pemphigus; Phenytoin; Seizures | 2012 |
Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions.
Topics: Biomarkers, Pharmacological; Carbamazepine; Drug Hypersensitivity; Genome-Wide Association Study; HLA-A Antigens; Humans; Lamotrigine; Phenytoin; Polymorphism, Single Nucleotide; Triazines | 2012 |
Thyroid hormones may contribute to vascular risk factors and atherosclerosis.
Topics: Anticonvulsants; Atherosclerosis; Carbamazepine; Carotid Artery, Common; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 2012 |
Variability of carbamazepine and valproate concentrations in elderly nursing home residents.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Data Interpretation, Statistical; Databases, Factual; Female; Humans; Male; Nursing Homes; Patients; Phenytoin; Seizures; Valproic Acid | 2012 |
Assessing adherence-based quality measures in epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Follow-Up Studies; Hospitalization; Humans; Levetiracetam; Male; Medication Adherence; Mental Disorders; Middle Aged; Odds Ratio; Phenytoin; Piracetam; Quality Indicators, Health Care; Retrospective Studies; Treatment Outcome; Young Adult | 2012 |
Seizure management at Auckland City Hospital Emergency Department between July and December 2009: time for a change?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Disease Management; Emergency Medical Services; Emergency Service, Hospital; Epilepsy; Female; Hospitals, Urban; Humans; Male; Middle Aged; New Zealand; Patient Care Team; Phenytoin; Retrospective Studies; Seasons; Seizures; Status Epilepticus; Tertiary Care Centers; Valproic Acid; Young Adult | 2012 |
The effect of combination therapy on the plasma concentrations of traditional antiepileptics: a retrospective study.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Risk Assessment; Risk Factors; Sex Factors; Valproic Acid; Young Adult | 2012 |
A rat model for LGI1-related epilepsies.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Reflex; Ethosuximide; Heterozygote; Homozygote; Humans; Intercellular Signaling Peptides and Proteins; Levetiracetam; Molecular Sequence Data; Mutation, Missense; Neurons; Phenytoin; Piracetam; Proteins; Rats, Mutant Strains | 2012 |
Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn).
Topics: Acetaldehyde; Animals; Carbamazepine; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Embryonic Stem Cells; Gene Expression Profiling; Gene Expression Regulation; In Vitro Techniques; Mice; Neural Stem Cells; Neurites; Penicillin G; Phenytoin; Silanes; Toxicity Tests; Triazoles | 2012 |
B-vitamin deficiency in patients treated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Vitamin B Deficiency | 2012 |
Pharmacokinetic simulation of fatal carbamazepine intoxication in 23-month old child following phenytoin discontinuation.
Topics: Anticonvulsants; Autopsy; Biotransformation; Carbamazepine; Computer Simulation; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Overdose; Drug Therapy, Combination; Fatal Outcome; Forensic Toxicology; Humans; Infant; Male; Models, Biological; Monte Carlo Method; Phenytoin; Poisoning; Seizures | 2013 |
Seizure recurrence and remission after switching antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cross-Over Studies; Humans; Male; Phenytoin; Recurrence; Remission Induction; Seizures; Young Adult | 2013 |
Cost-effectiveness of HLA-B*1502 genotyping in adult patients with newly diagnosed epilepsy in Singapore.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Cost-Benefit Analysis; Decision Making; Decision Trees; Epilepsy; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; HLA-B15 Antigen; Humans; Male; Middle Aged; Phenytoin; Singapore; Stevens-Johnson Syndrome | 2012 |
A novel microextraction by packed sorbent-gas chromatography procedure for the simultaneous analysis of antiepileptic drugs in human plasma and urine.
Topics: Alprazolam; Anticonvulsants; Carbamazepine; Epilepsy; Gas Chromatography-Mass Spectrometry; Humans; Oxcarbazepine; Phenytoin; Solid Phase Microextraction | 2012 |
Asymmetric dimethylarginine may contribute to vascular risk factors in patients receiving antiepileptic drug treatment.
Topics: Anticonvulsants; Atherosclerosis; Carbamazepine; Carotid Artery, Common; Epilepsy; Female; Humans; Male; Phenytoin; Valproic Acid | 2012 |
Comparative stroke risk of antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Propensity Score; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stroke; Valproic Acid; Young Adult | 2013 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Deconstructing the neural and ionic involvement of seizure-like events in the striatal network.
Topics: Action Potentials; Animals; Anticonvulsants; Benzofurans; Cannabinoid Receptor Antagonists; Carbamazepine; Corpus Striatum; Nerve Net; Neurons; Phenytoin; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Seizures | 2013 |
The antimanic-like effect of phenytoin and carbamazepine on methylphenidate-induced hyperlocomotion: role of voltage-gated sodium channels.
Topics: Animals; Antimanic Agents; Bipolar Disorder; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methylphenidate; Mice; Motor Activity; Phenytoin; Veratrine; Voltage-Gated Sodium Channels | 2013 |
Multidrug resistance-associated protein 1 decreases the concentrations of antiepileptic drugs in cortical extracellular fluid in amygdale kindling rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Epilepsy; Extracellular Fluid; Hippocampus; Kindling, Neurologic; Male; Microdialysis; Multidrug Resistance-Associated Proteins; Phenytoin; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Up-Regulation | 2013 |
First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Lamotrigine; Limit of Detection; Linear Models; Phenobarbital; Phenytoin; Reproducibility of Results; Triazines | 2013 |
Phenobarbital-induced severe cutaneous adverse drug reactions are associated with CYP2C19*2 in Thai children.
Topics: Adolescent; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Child; Child, Preschool; Cytochrome P-450 CYP2C19; DNA Mutational Analysis; Drug Hypersensitivity; Female; Genotype; HLA-B15 Antigen; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Polymorphism, Genetic; Skin; Thailand | 2013 |
Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin.
Topics: Action Potentials; Animals; Anticonvulsants; Carbamazepine; Computer Simulation; Dentate Gyrus; Markov Chains; Models, Biological; Nerve Net; Neurons; Phenytoin; Sodium Channels; Time Factors | 2013 |
HLA typing in Brazilian boys with aromatic antiepileptic drug-induced DRESS.
Topics: Alleles; Anticonvulsants; Brazil; Carbamazepine; Child; Drug Eruptions; Eosinophilia; Epilepsy; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Histocompatibility Testing; Humans; Male; Phenytoin | 2013 |
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensiti
Topics: Administration, Oral; Amoxicillin; Animals; Biomarkers; Carbamazepine; Drug Hypersensitivity; Flow Cytometry; Germinal Center; Hyperplasia; Immunoglobulin E; Lymphoid Tissue; Phenytoin; Rats; Rats, Inbred BN; Sulfamethoxazole | 2013 |
The quantitative effect of serum albumin, serum urea, and valproic acid on unbound phenytoin concentrations in children.
Topics: Adolescent; Anticonvulsants; Bilirubin; Carbamazepine; Child; Child, Preschool; Databases, Factual; Female; Humans; Infant; Infant, Newborn; Male; Netherlands; Nonlinear Dynamics; Phenytoin; Protein Binding; Retrospective Studies; Serum Albumin; Urea; Valproic Acid | 2014 |
Evaluating appropriateness of digoxin, carbamazepine, valproic acid, and phenytoin usage by therapeutic drug monitoring.
Topics: Animals; Carbamazepine; Digoxin; Humans; Monitoring, Physiologic; Phenytoin; Valproic Acid | 2013 |
Inhibitory effect of hydroxypropyl methylcellulose acetate succinate on drug recrystallization from a supersaturated solution assessed using nuclear magnetic resonance measurements.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Crystallization; Magnetic Resonance Spectroscopy; Methylcellulose; Molecular Structure; Phenytoin | 2013 |
Noninvasive screening for preclinical atherosclerosis in children on phenytoin or carbamazepine monotherapy: a cross sectional study.
Topics: Anticonvulsants; Atherosclerosis; Carbamazepine; Carotid Arteries; Carotid Intima-Media Thickness; Child; Cross-Sectional Studies; Endothelium, Vascular; Epilepsy; Female; Humans; Male; Phenytoin | 2013 |
Anti-epileptic drugs inhibit viability of synoviocytes in vitro.
Topics: Animals; Anticonvulsants; Arthritis, Rheumatoid; Carbamazepine; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Phenobarbital; Phenytoin; Rabbits; Synovial Membrane; Valproic Acid | 2013 |
Influence of organic surface coatings on the sorption of anticonvulsants on mineral surfaces.
Topics: Adsorption; Anticonvulsants; Carbamazepine; Environmental Pollutants; Ferric Compounds; Hydrogen-Ion Concentration; Metals; Phenytoin; Static Electricity; Surface Properties; Surface-Active Agents | 2013 |
Effect of CYP3A5 genotypes on the pharmacokinetics of carbamazepine when used as monotherapy or co-administered with phenytoin, phenobarbital or valproic acid in Thai patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2013 |
Interactions of levetiracetam with carbamazepine, phenytoin, topiramate and vigabatrin in the mouse 6Hz psychomotor seizure model - a type II isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Disease Models, Animal; Drug Combinations; Drug Interactions; Fructose; Hand Strength; Levetiracetam; Male; Mice; Phenytoin; Piracetam; Psychomotor Performance; Seizures; Topiramate; Vigabatrin | 2014 |
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Hospitals, Teaching; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigine.
Topics: Anticonvulsants; Brain; Carbamazepine; HEK293 Cells; Humans; Lamotrigine; Phenytoin; Protein Subunits; Sodium Channels; Triazines; Voltage-Gated Sodium Channel Blockers | 2014 |
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coculture Techniques; Connexin 43; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Gap Junctions; Inflammation; Microglia; Neuroglia; Phenytoin; Rats; Rats, Wistar; Transforming Growth Factor beta1; Valproic Acid | 2014 |
P-glycoprotein alters blood-brain barrier penetration of antiepileptic drugs in rats with medically intractable epilepsy.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Disease Models, Animal; Drug Resistance; Epilepsy; Male; Phenytoin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution; Up-Regulation; Verapamil | 2013 |
Lacosamide serum concentrations in adult patients with epilepsy: the influence of gender, age, dose, and concomitant antiepileptic drugs.
Topics: Acetamides; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 2014 |
Chlorination of N-methylacetamide and amide-containing pharmaceuticals. Quantum-chemical study of the reaction mechanism.
Topics: Acetamides; Acetaminophen; Amides; Carbamazepine; Chemistry, Pharmaceutical; Chlorine; Computer Simulation; Halogenation; Models, Chemical; Molecular Structure; Phenytoin; Quantum Theory; Solvents; Water | 2014 |
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Female; Forensic Toxicology; Humans; Hydrocortisone; Liver Cirrhosis; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Young Adult | 2014 |
Photochemical degradation of atenolol, carbamazepine, meprobamate, phenytoin and primidone in wastewater effluents.
Topics: Atenolol; Carbamazepine; Hydroxyl Radical; Meprobamate; Oxidants; Phenytoin; Photolysis; Primidone; Singlet Oxygen; Sunlight; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2015 |
Reboxetine and its influence on the action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Male; Memory, Long-Term; Mice; Morpholines; Motor Activity; Phenobarbital; Phenytoin; Reboxetine; Valproic Acid | 2014 |
Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Electroshock; Famotidine; Histamine H2 Antagonists; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 2014 |
Epilepsy in patients with gliomas: incidence and control of seizures.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Female; Glioma; Humans; Incidence; Japan; Levetiracetam; Male; Middle Aged; Neoplasm Grading; Phenytoin; Piracetam; Retrospective Studies; Seizures | 2015 |
Effects of preoperatively administered carbamazepine and phenytoin on rocuronium-induced neuromuscular block under sevoflurane anesthesia: a retrospective clinical study.
Topics: Adult; Aged; Androstanols; Anesthesia; Anesthesia Recovery Period; Anticonvulsants; Carbamazepine; Female; Humans; Male; Methyl Ethers; Middle Aged; Neuromuscular Blockade; Neuromuscular Nondepolarizing Agents; Phenytoin; Preoperative Care; Regression Analysis; Retrospective Studies; Rocuronium; Sevoflurane | 2014 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Clinical validation and implications of dried blood spot sampling of carbamazepine, valproic acid and phenytoin in patients with epilepsy.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Dried Blood Spot Testing; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenytoin; Treatment Outcome; Valproic Acid; Young Adult | 2014 |
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines | 2014 |
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Central Nervous System Depressants; Child, Preschool; Cytochrome P-450 CYP2E1; Disease Models, Animal; Endothelial Cells; Ethanol; Female; Humans; Infant; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neurons; Phenobarbital; Phenytoin; Status Epilepticus | 2014 |
Simple SPE-HPLC determination of some common drugs and herbicides of environmental concern by pulsed amperometry.
Topics: Atrazine; Benzothiadiazines; Carbamazepine; Carbon; Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Herbicides; Phenytoin; Rivers; Solid Phase Extraction; Water Pollutants, Chemical | 2015 |
HLA-B∗ 1502 is associated with carbamazepine induced Stevens-Johnson syndrome in North Indian population.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Female; Gene Expression; HLA-B15 Antigen; Humans; India; Male; Middle Aged; Phenytoin; Seizures; Stevens-Johnson Syndrome | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Effects of phenytoin and valproic acid on cognitive functions of Thai epileptic patients: a pilot study.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenytoin; Pilot Projects; Thailand; Treatment Outcome; Valproic Acid | 2014 |
Phenytoin induced toxic epidermal necrolysis.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Phenytoin; Seizures; Stevens-Johnson Syndrome | 2014 |
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzhydryl Compounds; Brain; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Hand Strength; Male; Mice; Modafinil; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Sulfones; Valproic Acid | 2015 |
Antiepileptic prophylaxis following severe traumatic brain injury within a military cohort.
Topics: Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Case-Control Studies; Chemoprevention; Cohort Studies; Humans; Levetiracetam; Military Personnel; Phenytoin; Piracetam; Retrospective Studies; Seizures; Trauma Severity Indices; Valproic Acid | 2016 |
New benzo[d]thiazol-2-yl-aminoacetamides as potential anticonvulsants: synthesis, activity and prediction of molecular properties.
Topics: Acetamides; Animals; Anticonvulsants; Benzothiazoles; Carbamazepine; Computer Simulation; Disease Models, Animal; Drug Design; Electroshock; Mice; Models, Biological; Molecular Structure; Pentylenetetrazole; Phenytoin; Seizures; Structure-Activity Relationship | 2015 |
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2015 |
Status epilepticus induction has prolonged effects on the efficacy of antiepileptic drugs in the 6-Hz seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Levetiracetam; Male; Mice; Phenytoin; Pilocarpine; Piracetam; Seizures; Status Epilepticus; Treatment Outcome | 2015 |
Efficacy of phenytoin, valproic acid, carbamazepine and new antiepileptic drugs on control of late-onset post-stroke epilepsy in Taiwan.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cohort Studies; Female; Humans; Male; Middle Aged; National Health Programs; Outcome Assessment, Health Care; Phenytoin; Seizures; Stroke; Taiwan; Valproic Acid | 2015 |
[DRESS syndrome: Report of nine cases].
Topics: Adolescent; Adult; Aged; Carbamazepine; Dexamethasone; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Female; Humans; Male; Phenytoin; Prednisone; Retrospective Studies; Young Adult | 2015 |
Effect of carbamazepine or phenytoin therapy on blood level of intravenously administered midazolam: a prospective cohort study.
Topics: Administration, Intravenous; Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Midazolam; Phenytoin; Prospective Studies; Young Adult | 2016 |
Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in monotherapy and bitherapy.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Carbamazepine; Child; China; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsy; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Phenobarbital; Phenytoin; Polymorphism, Single Nucleotide; Valproic Acid; Young Adult | 2015 |
Concentration of antiepileptic drugs in persons with epilepsy: a comparative study in serum and saliva.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Saliva; Young Adult | 2016 |
Mexiletine and its Interactions with Classical Antiepileptic Drugs: An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mexiletine; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Tissue Distribution; Valproic Acid | 2016 |
Propafenone enhances the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Propafenone; Valproic Acid | 2016 |
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult | 2016 |
The effects of cimetidine chronic treatment on conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Cimetidine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2016 |
Anti-epileptic drugs and bone loss: Phenytoin reduces pro-collagen I and alters the electrophoretic mobility of osteonectin in cultured bone cells.
Topics: Animals; Anticonvulsants; Blotting, Western; Bone and Bones; Carbamazepine; Cell Line; Collagen Type I; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Fructose; Gene Expression Profiling; Lamotrigine; Levetiracetam; Microscopy, Confocal; Osteoblasts; Osteonectin; Phenytoin; Piracetam; Procollagen; Real-Time Polymerase Chain Reaction; Topiramate; Triazines; Valproic Acid | 2016 |
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model.
Topics: Administration, Oral; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Gastrointestinal Tract; Hepatocytes; Humans; Liver; Models, Biological; Phenobarbital; Phenytoin; Rifampin; RNA, Messenger | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein.
Topics: Anticonvulsants; Biomarkers; C-Reactive Protein; Carbamazepine; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Lipids; Male; Middle Aged; Phenytoin; Piracetam; Time Factors; Topiramate; Treatment Outcome; Triazines; Zonisamide | 2016 |
Medication prescribing and patient-reported outcome measures in people with epilepsy in Bhutan.
Topics: Adult; Aged; Anticonvulsants; Bhutan; Carbamazepine; Drug Prescriptions; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Patient Reported Outcome Measures; Phenytoin; Quality of Life; Surveys and Questionnaires; Valproic Acid | 2016 |
Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.
Topics: Animals; Animals, Newborn; Brain; Carbamazepine; Cell Movement; Enzyme Induction; Female; Gene Expression Regulation, Developmental; Genes, Developmental; Glucuronosyltransferase; Humans; Mice, Inbred C57BL; Mice, Transgenic; Milk, Human; Neurodevelopmental Disorders; Phenytoin; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; RNA, Messenger; Rotarod Performance Test; Thyroxine | 2016 |
The antiepileptic medications carbamazepine and phenytoin inhibit native sodium currents in murine osteoblasts.
Topics: Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Gene Expression Regulation; Membrane Potentials; Mice; Mice, Inbred C57BL; Osteoblasts; Patch-Clamp Techniques; Phenytoin; RNA, Messenger; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2016 |
Comparative persistence of antiepileptic drugs in patients with epilepsy: A STROBE-compliant retrospective cohort study.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Hospitalization; Humans; Lamotrigine; Male; Medication Adherence; Middle Aged; Oxcarbazepine; Phenytoin; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Topiramate; Triazines; Valproic Acid; Young Adult | 2016 |
Hyperhomocysteinaemia in children receiving phenytoin and carbamazepine monotherapy: a cross-sectional observational study.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Long-Term Care; Male; Phenytoin; Vitamin B Complex | 2017 |
Efficacy of sodium channel blockers in SCN2A early infantile epileptic encephalopathy.
Topics: Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Male; NAV1.2 Voltage-Gated Sodium Channel; Phenytoin; Sodium Channel Blockers; Spasms, Infantile; Treatment Outcome | 2017 |
Population Pharmacokinetics of Topiramate in Japanese Pediatric and Adult Patients With Epilepsy Using Routinely Monitored Data.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Child; Child, Preschool; Drug Monitoring; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Monitoring, Physiologic; Phenytoin; Seizures; Topiramate; Young Adult | 2017 |
Association between antiepileptic drug dose and long-term response in patients with refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistant Epilepsy; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lamotrigine; Longitudinal Studies; Male; Middle Aged; Phenytoin; Retrospective Studies; Time Factors; Treatment Outcome; Triazines; Valproic Acid | 2017 |
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines | 2017 |
Lamotrigine Drug Interactions in Combination Therapy and the Influence of Therapeutic Drug Monitoring on Clinical Outcomes of Adult Patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Phenytoin; Piracetam; Seizures; Topiramate; Triazines; Valproic Acid | 2017 |
Homocysteine Metabolism and Hematological Parameters in Early Stage of Phenytoin Treated Epileptic Children.
Topics: Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phenytoin; Vitamin B 12 | 2017 |
The association of HLA B*15:02 allele and Stevens-Johnson syndrome/toxic epidermal necrolysis induced by aromatic anticonvulsant drugs in a South Indian population.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Female; HLA-B15 Antigen; Humans; Hydrocarbons, Aromatic; India; Male; Middle Aged; Phenytoin; Stevens-Johnson Syndrome; Young Adult | 2018 |
The effects of felbamate on appetitive and aversive instrumental learning in adult rats.
Topics: Animals; Anticonvulsants; Appetitive Behavior; Avoidance Learning; Carbamazepine; Cognition; Conditioning, Operant; Felbamate; Female; Phenylcarbamates; Phenytoin; Propylene Glycols; Rats; Rats, Sprague-Dawley; Valproic Acid | 2018 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Biomarkers; Carbamazepine; Cytochrome P-450 CYP3A Inducers; Drug Monitoring; Enzyme Induction; Female; Humans; Hydroxycholesterols; Levetiracetam; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Young Adult | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study.
Topics: Adult; Aged; Allopurinol; Anticonvulsants; Carbamazepine; Case-Control Studies; Drug Combinations; Epilepsy; Female; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Phenytoin; Stevens-Johnson Syndrome; Taiwan | 2018 |
Evaluation of a lymphocyte transformation test and cytokine detection assay to identify phenytoin and carbamazepine provoked DRESS or SJS/TEN in epilepsy patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Cytokines; Drug Hypersensitivity Syndrome; Epilepsy; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Phenytoin; Stevens-Johnson Syndrome | 2018 |
Frequency of drug combinations between enzyme-inducing first-generation antiepileptic drugs and inducible drugs in patients with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Italy; Male; Middle Aged; Phenobarbital; Phenytoin | 2018 |
Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Dronedarone; Drug Interactions; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
HLA-B*5701 and HLA-B*5801 in an Indian patient with anti-epileptics induced cutaneous adverse drug reactions.
Topics: Acute Generalized Exanthematous Pustulosis; Alleles; Anticonvulsants; Carbamazepine; Epilepsy; Genetic Predisposition to Disease; HLA-B Antigens; Humans; India; Male; Middle Aged; Phenytoin | 2019 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memory; Memory Disorders; Mothers; Phenytoin; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Prospective Studies; Valproic Acid | 2019 |
Lidocaine and carbamazepine inhibit while phenytoin and lamotrigine paradoxically enhance the insect neuromuscular transmission.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Carbamazepine; Diptera; Lamotrigine; Lidocaine; Phenytoin; Synaptic Transmission; Voltage-Gated Sodium Channel Blockers | 2019 |
New derivative of 1,2,4-triazole-3-thione (TP427) potentiates the anticonvulsant action of valproate, but not that of carbamazepine, phenytoin or phenobarbital in the mouse tonic-clonic seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
European Academy of Neurology guideline on trigeminal neuralgia.
Topics: Analgesics; Carbamazepine; Decompression, Surgical; Europe; Gabapentin; Humans; Neurology; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia | 2019 |
Clinical profiles associated with serum perampanel concentrations in children with refractory epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dizziness; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Absence; Female; Humans; Infant; Male; Nitriles; Phenobarbital; Phenytoin; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Silymarin as a flavonoid-type P-glycoprotein inhibitor with impact on the pharmacokinetics of carbamazepine, oxcarbazepine and phenytoin in rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Drug Interactions; Male; Oxcarbazepine; Phenytoin; Rats; Rats, Wistar; Silymarin; Tissue Distribution; Verapamil | 2021 |
Management and attitudes toward patients with epilepsy in general practice: How far have we come in three decades?
Topics: Adult; Anticonvulsants; Attitude of Health Personnel; Australia; Carbamazepine; Clinical Competence; Electroencephalography; Epilepsy; Female; Follow-Up Studies; General Practitioners; Humans; Lamotrigine; Levetiracetam; Magnetic Resonance Imaging; Male; Middle Aged; Neurology; Phenytoin; Referral and Consultation; Surveys and Questionnaires; Valproic Acid | 2019 |
Estimation of apparent clearance of valproic acid in adult Saudi patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Phenytoin; Retrospective Studies; Saudi Arabia; Topiramate; Valproic Acid; Young Adult | 2019 |
Elevated serum alkaline phosphatase in epilepsy: effect of age and treatment.
Topics: Adolescent; Adult; Age Factors; Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Epilepsy; Female; Humans; India; Male; Phenytoin; Seizures; Valproic Acid; Young Adult | 2020 |
Genotoxicity assessment of antiepileptic drugs (AEDs) in human embryonic stem cells.
Topics: Anticonvulsants; Carbamazepine; DNA Damage; Epilepsy; Female; Human Embryonic Stem Cells; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy | 2019 |
Anti-epileptic drug and folic acid usage during pregnancy, seizure and malformation outcomes: Changes over two decades in the Kerala Registry of Epilepsy and Pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Folic Acid; Humans; India; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Pregnancy; Pregnancy Complications; Registries; Seizures; Topiramate; Valproic Acid | 2020 |
Patterns of antiepileptic drug use among elderly patients with epilepsy: 2004-2015.
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Epilepsy; Female; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; Seizures; Zonisamide | 2020 |
Influence of dose and antiepileptic comedication on brivaracetam serum concentrations in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Pyrrolidinones; Retrospective Studies; Young Adult | 2020 |
Effects of antiepileptic drugs on electroencephalography (EEG): Insights and applicability.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2020 |
A model-based analysis of phenytoin and carbamazepine toxicity treatment using binding-competition during hemodialysis.
Topics: Aspirin; Binding, Competitive; Carbamazepine; Humans; Ibuprofen; Models, Chemical; Phenytoin; Protein Binding; Renal Dialysis | 2020 |
COVID-19 & antiepileptic drugs: Should we pay attention?
Topics: Anticonvulsants; Antiviral Agents; Atazanavir Sulfate; Betacoronavirus; Carbamazepine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Combinations; Drug Interactions; Humans; Lopinavir; Pandemics; Phenytoin; Pneumonia, Viral; Ritonavir; SARS-CoV-2; Seizures | 2020 |
A Rapid LC-MS-MS Method for the Quantitation of Antiepileptic Drugs in Urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Drug Monitoring; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenytoin; Tandem Mass Spectrometry; Topiramate | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid | 2020 |
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers | 2020 |
Pharmacokinetics, tolerability, and clinical effectiveness of perampanel in Japanese patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Japan; Male; Phenobarbital; Phenytoin; Seizures; Treatment Outcome | 2020 |
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity Syndrome; Female; Humans; Incidence; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenytoin; Republic of Korea; Severity of Illness Index; Stevens-Johnson Syndrome; Topiramate; Young Adult; Zonisamide | 2021 |
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid | 2021 |
Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Epoxide Hydrolases; Humans; Phenytoin | 2021 |
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide | 2021 |
Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy; Female; Male; Memory, Long-Term; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2021 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; Female; Humans; Incidence; Japan; Lamotrigine; Levetiracetam; Logistic Models; Male; Middle Aged; Odds Ratio; Phenytoin; Risk Factors; Stevens-Johnson Syndrome | 2021 |
Effects of antiepileptic drugs' administration during pregnancy on the nerve cell proliferation and axonal outgrowth of human neuroblastoma SH-SY5Y nerve cells.
Topics: Anticonvulsants; Carbamazepine; Cell Line, Tumor; Cell Proliferation; Child; Epilepsy; Female; Humans; Lamotrigine; NAV1.1 Voltage-Gated Sodium Channel; Neuroblastoma; Neuronal Outgrowth; Neurons; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2021 |
Post-stroke epilepsy and antiepileptic drug use in men and women.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Medication Adherence; Middle Aged; Phenytoin; Stroke; Sweden; Valproic Acid | 2021 |
The Impact of Strong Inducers on Direct Oral Anticoagulant Levels.
Topics: Administration, Oral; Aged; Anticoagulants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Monitoring; Female; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies; Rifampin | 2021 |
Chronic limbic epilepsy models for therapy discovery: Protocols to improve efficiency.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsy; Levetiracetam; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Rats; Seizures | 2021 |
Post-Traumatic Epilepsy in Zebrafish Is Drug-Resistant and Impairs Cognitive Function.
Topics: Animals; Anticonvulsants; Carbamazepine; Cognitive Dysfunction; Disease Models, Animal; Drug Resistant Epilepsy; Epilepsy, Post-Traumatic; Female; Male; Phenytoin; Valproic Acid; Zebrafish | 2021 |
The effect of antiepileptic drugs on re-myelinization of axons: Phenytoin, levetiracetam, carbamazepine, and valproic acid, used following traumatic brain injury.
Topics: Animals; Anticonvulsants; Axons; Brain Injuries, Traumatic; Carbamazepine; Levetiracetam; Phenytoin; Rats; Rats, Long-Evans; Remyelination; Treatment Outcome; Valproic Acid | 2021 |
Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results.
Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Cicatrix; Humans; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; Taiwan | 2022 |
Clinical characteristics of antiepileptic-induced liver injury in patients from the DILIN prospective study.
Topics: Adult; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Dyphylline; Gabapentin; Humans; Lamotrigine; Middle Aged; Phenytoin; Prospective Studies; Seizures; United States | 2022 |
Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy | 2022 |
Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization.
Topics: Allopurinol; Carbamazepine; Humans; Pharmacovigilance; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; World Health Organization | 2022 |
Simultaneous Quantification of 11 Antiseizure Medications and Metabolites in Serum for Therapeutic Drug Monitoring Using High-Performance Liquid Chromatography with Ultraviolet Detection: A Short Communication.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenytoin | 2022 |
Pharmacokinetic Interactions Between Antiseizure and Psychiatric Medications.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Phenytoin | 2023 |
A Phenytoin-Induced Ataxia Mimicking a Stroke.
Topics: Ataxia; Carbamazepine; Female; Humans; Middle Aged; Phenytoin; Stroke; Valproic Acid | 2022 |
Long-Term Effects of Antiseizure Medications.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenytoin; Seizures | 2022 |
Trimetazidine, an Anti-Ischemic Drug, Reduces the Antielectroshock Effects of Certain First-Generation Antiepileptic Drugs.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Trimetazidine; Valproic Acid | 2022 |
Ranolazine Interacts Antagonistically with Some Classical Antiepileptic Drugs-An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Ranolazine; Seizures | 2022 |
Development of a useful single-reference HPLC method for therapeutic drug monitoring of phenytoin and carbamazepine in human plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenytoin | 2023 |
A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications.
Topics: Anticonvulsants; Butyrate Response Factor 1; Carbamazepine; Humans; Peptide Elongation Factors; Phenytoin; Pilot Projects; Poly(A)-Binding Protein I; Protein Serine-Threonine Kinases; Research Design; Transcription Factors; Valproic Acid | 2023 |
Anticonvulsant fatalities reported to the American Association of Poison Control Centers 2000 - 2019.
Topics: Aged; Anticonvulsants; Benzodiazepines; Carbamazepine; Humans; Phenytoin; Poison Control Centers; Retrospective Studies; Suicide; United States; Valproic Acid | 2023 |
Interaction of Varenicline with Classic Antiseizure Medications in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Varenicline | 2023 |
A Survey of Therapeutic Drug Monitoring Status in China.
Topics: Benzodiazepines; Carbamazepine; China; Drug Monitoring; Humans; Phenytoin; Surveys and Questionnaires | 2023 |
HLA alleles and antiseizure medication-induced cutaneous reactions in Brazil: A case-control study.
Topics: Alleles; Brazil; Carbamazepine; Case-Control Studies; HLA-A Antigens; HLA-B Antigens; Humans; Oxcarbazepine; Phenobarbital; Phenytoin | 2023 |
External validation of the AntiEpileptic Drug Monitoring in PREgnancy (EMPiRE) model for predicting seizures in pregnant women with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenytoin; Pregnancy; Pregnant Women; Prospective Studies | 2023 |
Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic-clonic seizure model: an isobolographic transformation.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures | 2023 |