phenytoin has been researched along with carbamazepine epoxide in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (36.67) | 18.7374 |
| 1990's | 14 (46.67) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huber, VJ; Kwee, IL; Nakada, T; Tsujita, M | 1 |
| Eadie, MJ; McKauge, L; Tyrer, JH | 1 |
| Rosenmund, H; Wad, N | 1 |
| Lindhout, D; Meijer, JW; Meinardi, H; Nau, H | 1 |
| Briggle, TV; Guterman, A; McManus, DQ; Perchalski, R; Ramsay, RE; Vazquez, D; Wong, P; Yost, RA | 1 |
| Dimanico, U; Gianelli, M; Monaco, F; Mutani, R | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R; Villagrán, R | 1 |
| Graves, NM; Miller, SA; Remmel, RP | 1 |
| Eadie, MJ; Herkes, GK; McKinnon, GE | 1 |
| Macdonald, RL; McLean, MJ | 1 |
| Riad, LE; Sawchuk, RJ | 1 |
| Asberg, A; Haffner, F | 1 |
| Berg, JD; Buckley, BM | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Neels, HM; Scharpé, SL; Totté, JA; Verkerk, RM; Vlietinck, AJ | 1 |
| Meijer, JW; Rambeck, B; Riedmann, M | 1 |
| Brown, RD; Rane, A; van Boxtel, CJ; Wilson, JT | 1 |
| Delgado, MR; Liu, H | 1 |
| Jones, SR; Ramachandran, S; Underhill, S | 1 |
| Ahmann, PA; Cascino, GD; Ruggles, KH; So, EL; Weatherford, KW | 1 |
| Graves, NM; Leppik, IE; Remmel, RP; Wagner, ML | 1 |
| Gidal, BE; Lensmeyer, GL; Wiebe, DA | 1 |
| Bhatti, MM; Hanson, GD; Schultz, L | 1 |
| Dutton, J; Higgins, G; Hughes, A; Roberts, NB | 1 |
| Donnelly, A; Potter, JM | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R | 1 |
| Jiao, Z; Shi, XJ; Zhao, ZG; Zhong, MK | 1 |
| Bertucci, C; Chaves, AR; Dreossi, SA; Malfará, WR; Queiroz, ME; Queiroz, RH; Valério, DA | 1 |
| Galceran, MT; Huerta-Fontela, M; Ventura, F | 1 |
| Fan, Y; Ma, K; Qu, L; Wang, W; Yin, Z | 1 |
1 trial(s) available for phenytoin and carbamazepine epoxide
| Article | Year |
|---|---|
Effect of felbamate on carbamazepine and its major metabolites.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols | 1993 |
29 other study(ies) available for phenytoin and carbamazepine epoxide
| Article | Year |
|---|---|
Inhibition of aquaporin 4 by antiepileptic drugs.
Topics: Animals; Anticonvulsants; Aquaporin 4; Computer Simulation; Drug Evaluation, Preclinical; Humans; Oocytes; Protein Binding; Thermodynamics; Xenopus | 2009 |
The epoxide of carbamazepine.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Biotransformation; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Methods; Middle Aged; Phenytoin | 1979 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
A simple and disposable visual measuring device to assay antiepileptic drugs from whole blood samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Simultaneous assay of felbamate plus carbamazepine, phenytoin, and their metabolites by liquid chromatography with mobile phase optimization.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenylcarbamates; Phenytoin; Propylene Glycols | 1990 |
Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Saliva; Spectrophotometry, Ultraviolet | 1989 |
Carbamazepine and 10,11-epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture.
Topics: Action Potentials; Animals; Carbamazepine; Cells, Cultured; Central Nervous System; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; Membrane Potentials; Mice; Neurons; Phenytoin; Sodium; Spinal Cord | 1986 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
Analysis of serum concentration of phenobarbital, phenytoin, carbamazepine and carbamazepine 10,11-epoxide by solvent-recycled liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Rapid measurement of anticonvulsant drug concentrations in the out-patient clinic, using HPLC with direct injection of plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin | 1987 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level/dose ratios in epileptic children.
Topics: Biotransformation; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Male; Oxidoreductases; Phenobarbital; Phenytoin | 1995 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Seizure exacerbation and status epilepticus related to carbamazepine-10,11-epoxide.
Topics: Adult; Age of Onset; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Seizures; Status Epilepticus | 1994 |
Optimized high-performance liquid chromatographic method for determination of lamotrigine in serum with concomitant determination of phenytoin, carbamazepine, and carbamazepine epoxide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenytoin; Triazines | 1997 |
Simultaneous determination of phenytoin, carbamazepine, and 10,11-carbamazepine epoxide in human plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenytoin; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1998 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Carbamazepine-10,11-epoxide in therapeutic drug monitoring.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Humans; Lamotrigine; Phenytoin; Sodium Channels; Triazines; Valproic Acid | 1998 |
Comparison between premortem and postmortem serum concentrations of phenobarbital, phenytoin, carbamazepine and its 10,11-epoxide metabolite in institutionalized patients with epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postmortem Changes; Time Factors | 1999 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Sensitivity and Specificity | 2008 |
Occurrence and removal of pharmaceuticals and hormones through drinking water treatment.
Topics: Atenolol; Carbamazepine; Hormones; Hydrochlorothiazide; Ozone; Pharmaceutical Preparations; Phenytoin; Sotalol; Water Pollutants, Chemical; Water Purification; Water Supply | 2011 |
Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |