phenytoin and beta-naphthoflavone

phenytoin has been researched along with beta-naphthoflavone in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Baidya, ATK; Das, B; Kumar, R; Mathew, AT; Yadav, AK	1
Kitteringham, NR; Park, BK; Riley, RJ; Roberts, P	1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM	1

Reviews

1 review(s) available for phenytoin and beta-naphthoflavone

Article	Year
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery. Bioorganic & medicinal chemistry, 2022, 02-15, Volume: 56 Topics: Drug Discovery; Hydrogen Bonding; Molecular Structure; Prodrugs; Solubility	2022

Other Studies

2 other study(ies) available for phenytoin and beta-naphthoflavone

Article	Year
Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes. Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12 Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin	1990
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3 Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics	1999

Article

Year

Formation of cytotoxic metabolites from phenytoin, imipramine, desipramine, amitriptyline and mianserin by mouse and human hepatic microsomes.

Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

Topics: 7-Alkoxycoumarin O-Dealkylase; Amitriptyline; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Desipramine; Dibenzoxazepines; Enzyme Induction; Humans; Imipramine; Injections, Intraperitoneal; Male; Mianserin; Mice; Mice, Inbred CBA; Microsomes, Liver; Phenobarbital; Phenytoin

1990

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.

Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics

1999