phenytoin has been researched along with benzocaine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM | 1 |
| Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
| Rubino, JT; Yalkowsky, SH | 2 |
| Green, SL; McClure, DE; Torreilles, SL | 1 |
| Chao, R; Corry, B; Martin, LJ | 1 |
| Corry, B; Martin, LJ | 1 |
| Allen, TW; Boiteux, C; French, C; French, RJ; Vorobyov, I; Yarov-Yarovoy, V | 1 |
14 other study(ies) available for phenytoin and benzocaine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Molecular characteristics for solid-state limited solubility.
Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility | 2008 |
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship | 2009 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Cosolvency and cosolvent polarity.
Topics: Benzocaine; Chemical Phenomena; Chemistry; Diazepam; Hydrogen Bonding; Mathematics; Phenytoin; Solubility; Surface Tension; Water | 1987 |
Cosolvency and deviations from log-linear solubilization.
Topics: Benzocaine; Chemical Phenomena; Chemistry; Diazepam; Mathematics; Phenytoin; Solubility; Solvents; Water | 1987 |
Evaluation and refinement of euthanasia methods for Xenopus laevis.
Topics: Aminobenzoates; Animals; Benzocaine; Euthanasia, Animal; Pentobarbital; Phenytoin; Time Factors; Unconsciousness; Xenopus laevis | 2009 |
Molecular dynamics simulation of the partitioning of benzocaine and phenytoin into a lipid bilayer.
Topics: Anesthetics, Local; Benzocaine; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phenytoin; Phosphatidylcholines; Thermodynamics | 2014 |
Locating the route of entry and binding sites of benzocaine and phenytoin in a bacterial voltage gated sodium channel.
Topics: Bacterial Proteins; Benzocaine; Binding Sites; Computational Biology; Hydrophobic and Hydrophilic Interactions; Models, Biological; Molecular Dynamics Simulation; Phenytoin; Thermodynamics; Voltage-Gated Sodium Channels | 2014 |
Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel.
Topics: Amino Acid Sequence; Anesthetics, Local; Anticonvulsants; Arcobacter; Benzocaine; Binding Sites; Computer Simulation; Membranes, Artificial; Models, Molecular; Molecular Sequence Data; Phenytoin; Protein Structure, Secondary; Protein Subunits; Sequence Alignment; Thermodynamics; Voltage-Gated Sodium Channels | 2014 |