phenytoin and baclofen

phenytoin has been researched along with baclofen in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199022 (47.83)18.7374
1990's13 (28.26)18.2507
2000's7 (15.22)29.6817
2010's3 (6.52)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Baker, JK; Wall, GM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Bissada, NK; Finkbeiner, AE; Welch, LT1
Amabeoku, GJ; Chikuni, O2
Patsalos, PN; Zakrzewska, JM1
Husag, L; Reber, M1
Fredow, G; Löscher, W1
Fromm, GH3
Martinez, C; Montini, C; Oliva, J; Ramirez, H1
Aurellano-Hoh, ZR1
Dalessio, DJ2
Chweh, AY; Swinyard, EA; Wolf, HH1
Arias, MJ1
Kaeser, HE1
Leopold, HC; Möbius, E; Paulus, WM1
Leo, A; Marano, E; Steardo, L1
Czuczwar, SJ; Kleinrok, Z; Kozicka, M1
Chattha, AS; Fromm, GH; Glass, JD; Terrence, CF1
Chattha, AS; Fromm, GH; Terrence, CF2
Cohen, JS; Diamond, S; Freitag, FG1
Fromm, GH; Maroon, JC; Terrence, CF1
Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, WA1
Hershey, LA1
Maxwell, S; Sidebottom, A1
Haas, KZ; Moshé, SL; Sperber, EF; Velísek, L; Velísková, J1
Dolphin, AC; Kobrinsky, EM; Pearson, HA1
Dubowitz, V; Heckmatt, JZ; Ransley, YF; Rodillo, E; Thomas, NH1
Mauskop, A1
George, B; Kulkarni, SK1
Zakrzewska, JM1
Gobetti, JP; Türp, JC1
Das, B; Saha, SP1
Rozen, TD1
Watson, CP1
Keppel Hesselink, JM; Kopsky, DJ1

Reviews

17 review(s) available for phenytoin and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Uropharmacology: X. Central nervous system stimulants and depressants.
    Urology, 1979, Volume: 13, Issue:4

    Topics: Amphetamines; Anesthetics; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Benzodiazepines; Central Nervous System Agents; Chloral Hydrate; Humans; Imipramine; Levodopa; Meperidine; Meprobamate; Morphine; Nortriptyline; Paraldehyde; Phenothiazines; Phenytoin; Picrotoxin; Reserpine; Strychnine; Urinary Tract

1979
Drugs used in the management of trigeminal neuralgia.
    Oral surgery, oral medicine, and oral pathology, 1992, Volume: 74, Issue:4

    Topics: Anticonvulsants; Baclofen; Carbamazepine; Clonazepam; Humans; Oxcarbazepine; Phenytoin; Trigeminal Neuralgia; Valproic Acid

1992
[The current treatment of trigeminal neuralgia. Experience in 162 thermorhizotomies].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Dec-22, Volume: 81, Issue:52

    Topics: Aged; Baclofen; Carbamazepine; Diagnosis, Differential; Electrocoagulation; Facial Neuralgia; Humans; Phenytoin; Tic Disorders; Trigeminal Ganglion; Trigeminal Neuralgia

1992
Clinical pharmacology of drugs used to treat head and face pain.
    Neurologic clinics, 1990, Volume: 8, Issue:1

    Topics: Baclofen; Carbamazepine; Facial Pain; Humans; Migraine Disorders; Phenytoin; Trigeminal Neuralgia

1990
The pharmacology of trigeminal neuralgia.
    Clinical neuropharmacology, 1989, Volume: 12, Issue:3

    Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia; Trigeminal Nuclei

1989
Medical treatment of the major neuralgias.
    Seminars in neurology, 1988, Volume: 8, Issue:4

    Topics: Baclofen; Carbamazepine; Chlorphenesin; Combined Modality Therapy; Facial Neuralgia; Glossopharyngeal Nerve; Humans; Phenytoin; Trigeminal Neuralgia

1988
[Trigeminal neuralgia. Treatment].
    Revista clinica espanola, 1985, Volume: 176, Issue:8

    Topics: Baclofen; Carbamazepine; Glycerol; Humans; Nerve Block; Nerve Compression Syndromes; Phenytoin; Trigeminal Nerve; Trigeminal Neuralgia

1985
Effects of different classes of antiepileptic drugs on brain-stem pathways.
    Federation proceedings, 1985, Volume: 44, Issue:8

    Topics: Animals; Anticonvulsants; Baclofen; Brain Stem; Carbamazepine; Disease Models, Animal; Electroshock; Ethosuximide; Phenytoin; Reticular Formation; Valproic Acid

1985
Drug-induced myasthenic syndromes.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 100

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseases; Baclofen; Carnitine; Collagen Diseases; Diazepam; Female; Humans; Male; Middle Aged; Muscular Diseases; Myasthenia Gravis; Neuromuscular Junction; Penicillamine; Phenytoin; Streptomycin; Synaptic Transmission; Syndrome

1984
The medical and surgical management of trigeminal neuralgia.
    Journal of clinical pharmacy and therapeutics, 1995, Volume: 20, Issue:1

    Topics: Baclofen; Carbamazepine; Combined Modality Therapy; Facial Nerve; Humans; Phenytoin; Postoperative Complications; Risk Assessment; Trigeminal Neuralgia

1995
The development of epilepsy in the paediatric brain.
    Seizure, 1994, Volume: 3, Issue:4

    Topics: Age Factors; Animals; Baclofen; Child; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Humans; Infant, Newborn; Kainic Acid; Kindling, Neurologic; Phenytoin; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate

1994
Trigeminal neuralgia.
    Primary dental care : journal of the Faculty of General Dental Practitioners (UK), 1997, Volume: 4, Issue:1

    Topics: Anticonvulsants; Baclofen; Carbamazepine; Diagnosis, Differential; Humans; Incidence; Muscle Relaxants, Central; Phenytoin; Trigeminal Neuralgia

1997
Trigeminal neuralgia--an update.
    Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2000, Volume: 21, Issue:4

    Topics: Acupuncture Analgesia; Anticonvulsants; Baclofen; Carbamazepine; Facial Pain; GABA Agonists; Homeopathy; Humans; Neurosurgical Procedures; Phenytoin; Trigeminal Neuralgia

2000
Trigeminal neuralgia: current concepts and management.
    Journal of the Indian Medical Association, 2001, Volume: 99, Issue:12

    Topics: Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Humans; Phenytoin; Pimozide; Radiosurgery; Trigeminal Ganglion; Trigeminal Neuralgia

2001
Trigeminal neuralgia and glossopharyngeal neuralgia.
    Neurologic clinics, 2004, Volume: 22, Issue:1

    Topics: Analgesics, Non-Narcotic; Anticonvulsants; Baclofen; Carbamazepine; GABA Agonists; Glossopharyngeal Nerve Diseases; Humans; Phenytoin; Trigeminal Neuralgia

2004
Management issues of neuropathic trigeminal pain from a medical perspective.
    Journal of orofacial pain, 2004,Fall, Volume: 18, Issue:4

    Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia

2004

Trials

2 trial(s) available for phenytoin and baclofen

ArticleYear
Efficacy of baclofen in trigeminal neuralgia and some other painful conditions. A clinical trial.
    European neurology, 1984, Volume: 23, Issue:1

    Topics: Adult; Amputation Stumps; Baclofen; Carbamazepine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Neuralgia; Phenytoin; Radiculopathy; Substance P; Tabes Dorsalis; Trigeminal Neuralgia

1984
Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up.
    Annals of neurology, 1984, Volume: 15, Issue:3

    Topics: Adult; Aged; Baclofen; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenytoin; Time Factors; Trigeminal Neuralgia

1984

Other Studies

27 other study(ies) available for phenytoin and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship

1989
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of some GABAergic agents on quinine-induced seizures in mice.
    Experientia, 1992, Jul-15, Volume: 48, Issue:7

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Phenytoin; Quinine; Receptors, GABA-A; Seizures

1992
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
    European journal of pharmacology, 1991, Jan-10, Volume: 192, Issue:2

    Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid

1991
[Pharmacotherapy of trigeminal neuralgia].
    Odontologia chilena, 1989, Volume: 37, Issue:2

    Topics: Amphetamines; Baclofen; Carbamazepine; Female; Humans; Imipramine; Male; Phenytoin; Trigeminal Neuralgia

1989
Trigeminal neuralgia.
    Middle East journal of anaesthesiology, 1989, Volume: 10, Issue:1

    Topics: Adult; Anesthesia, General; Baclofen; Carbamazepine; Chlorphenesin; Female; Hematologic Tests; Humans; Phenytoin; Physical Examination; Preanesthetic Medication; Trigeminal Neuralgia

1989
Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Phenytoin; Postural Balance; Seizures

1986
[Treatment of typical trigeminus neuralgias. Overview of the current state of drug and surgical therapy].
    Fortschritte der Medizin, 1984, Oct-11, Volume: 102, Issue:38

    Topics: Adult; Antipsychotic Agents; Baclofen; Carbamazepine; Chlorphenesin; Electrocoagulation; Female; Humans; Male; Middle Aged; Muscle Hypotonia; Paresthesia; Phenytoin; Trigeminal Neuralgia

1984
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures

1980
Role of inhibitory mechanisms in trigeminal neuralgia.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Animals; Baclofen; Carbamazepine; Cats; Electric Stimulation; Maxillary Nerve; Neural Inhibition; Phenobarbital; Phenytoin; Synaptic Transmission; Trigeminal Neuralgia; Trigeminal Nuclei

1981
Cluster headache with trigeminal neuralgia. An uncommon association that may be more than coincidental.
    Postgraduate medicine, 1984, Feb-01, Volume: 75, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Baclofen; Carbamazepine; Chlorphenesin; Cluster Headache; Drug Therapy, Combination; Ergotamine; Ergotamines; Female; Humans; Lithium; Lithium Carbonate; Male; Methysergide; Middle Aged; Phenytoin; Trigeminal Neuralgia; Vascular Headaches

1984
Trigeminal neuralgia. Current concepts regarding etiology and pathogenesis.
    Archives of neurology, 1984, Volume: 41, Issue:11

    Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia

1984
Differential effect of antiepileptic and non-antiepileptic drugs on the reticular formation.
    Life sciences, 1984, Dec-24, Volume: 35, Issue:26

    Topics: Action Potentials; Animals; Anticonvulsants; Baclofen; Carbamazepine; Cats; Dose-Response Relationship, Drug; Epilepsy; Humans; Neurons; Phenytoin; Reticular Formation

1984
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
    Neuropharmacology, 1984, Volume: 23, Issue:2A

    Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate

1984
Baclofen in the treatment of neuralgia.
    Annals of internal medicine, 1984, Volume: 100, Issue:6

    Topics: Baclofen; Carbamazepine; Humans; Phenytoin; Trigeminal Neuralgia

1984
Trigeminal neuralgia. A practical approach to treatment.
    Drugs, 1982, Volume: 24, Issue:3

    Topics: Baclofen; Carbamazepine; Chlorphenesin; Humans; Microsurgery; Phenytoin; Trigeminal Neuralgia

1982
Low- and high-voltage-activated calcium channel currents and their modulation in the dorsal root ganglion cell line ND7-23.
    Neuroscience, 1994, Volume: 58, Issue:3

    Topics: Ammonium Chloride; Animals; Baclofen; Bradykinin; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cell Line; Dihydropyridines; Electrophysiology; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Neurotransmitter Agents; Nicotinic Acids; omega-Conotoxin GVIA; Oxadiazoles; Peptides; Phenytoin; Rats; Tumor Cells, Cultured

1994
Continuous muscle fibre activity (Isaacs' syndrome) in infancy: a report of two cases.
    Neuromuscular disorders : NMD, 1994, Volume: 4, Issue:2

    Topics: Baclofen; Carbamazepine; Electromyography; Female; Humans; Infant, Newborn; Male; Muscles; Muscular Diseases; Phenytoin; Syndrome; Treatment Failure

1994
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine

1993
Trigeminal neuralgia (tic douloureux).
    Journal of pain and symptom management, 1993, Volume: 8, Issue:3

    Topics: Baclofen; Carbamazepine; Diagnosis, Differential; Humans; Phenytoin; Trigeminal Neuralgia

1993
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid

1996
Phenytoin in topical formulations augments pain reduction of other topically applied analgesics in the treatment of trigeminal neuralgia.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Administration, Cutaneous; Aged; Analgesics; Baclofen; Drug Synergism; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Nociceptors; Pain Management; Phenytoin; Skin Cream; Time Factors; Touch; Trigeminal Neuralgia

2017