phenytoin and aspirin

phenytoin has been researched along with aspirin in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199056 (62.92)18.7374
1990's7 (7.87)18.2507
2000's13 (14.61)29.6817
2010's11 (12.36)24.3611
2020's2 (2.25)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Kavya, R; Nageswari, Y; Ragavendran, JV; Sreevatsan, N; Sriram, D; Stables, J; Vanitha, K; Yogeeswari, P1
Andricopulo, AD; Moda, TL; Montanari, CA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Asai, S; Kubodera, T; Nadai, T; Tatematsu, A; Yoshizumi, H1
Layzer, RB; Porter, RJ2
Shepard, TH1
Finn, A; Olanow, CW; Prussak, C1
Elfving, SM; Elonen, E; Neuvonen, PJ1
Wilson, JT1
Fritz, H1
Hall, RA; Liebling, LI; Nicholson, G1
Mützell, S1
Watson, AD1
McCombs, J1
Ali, S; Molinari, LM; Wells, PG; Wong, ST; Zubovits, JT1
Garcia de la Serrana, H; Mota, C; Puche, E; Saucedo, R1
Greco, GS; Nagai, MK; Wells, PG1
Fujii, T; Kawase, F; Sato, T; Tamura, A1
Goldman, AS; Gupta, C1
Chand, RP; Chuah, SP; Gururaj, AK1
Albertucci, M; Bailey, RT; Bonavina, L; DeMeester, TR; McChesney, L; Schwizer, W1
Baranetsky, NG; Chertow, BS; Leonard, RF; Sivitz, WI; Webb, MD1
Caraccio, TR; D'Agostino, R; Greensher, J; Mofenson, HC; Rossi, A1
Bochner, F; Eadie, MJ; Hooper, WD; Sutherland, JM; Tyrer, JH1
Friis, T; Hansen, MJ; Kolendorf, K; Siersbaek-Nielsen, K1
Oldendorf, WH1
Ente, G; Pochedly, C1
Fishbein, L; Flamm, WG1
Desnick, RJ; Hunninghake, DB; Krivit, W; Lockman, LA1
Pisciotta, AV1
Bick, M; Fishbein, L1
Wilson, J1
Nuss, GW; Risley, EA; Van Arman, CG1
Andreasen, F1
Naess, K1
Kramer, RL; Richens, A1
Trautmann, A1
Bhalla, TN; Bhargava, KP; Kohli, RP; Sinha, JN1
Lunde, KM1
Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K1
Meloff, K1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ1
Hynes, HE; Recker, RR1
Guillory, JK; Hwang, SC; Lach, JL1
Banfi, S; Consonni, P; Diena, A; Pifferi, G1
Hinz, JE; Pisciotta, AV; Ziebert, AP1
Greene, W1
Jacobs, AH1
Holtzman, JL1
Furst, DE1
Börner, W; Hoffmann, R; Moll, E; Reiners, C1
Inoue, F; Walsh, RJ1
D'Arcy, PF1
Finn, AL; Olanow, CW; Prussak, C1
Evens, RP; Fraser, DG; Ludden, TM; Sutherland, EW1
Paxton, JW1
Knott, PJ; Leonard, RF; Melnick, DE; Rankin, GO; Robinson, DS1
Ahmed, K; Bloch, R; Dickinson, CJ; Ingram, D; Sweeney, G1
Patil, PA; Wali, RS1
Eubanks, LE; Galen, W; McBurney, EI; Reed, R1
Malata, A; Masanjika, R; Sungani, FC1
Fitzgerald, DJ; Quinn, MJ1
MURPHY, BE; PATTEE, CJ1
STICKLER, GB1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R1
Fukuyama, H; Hashikawa, K; Matsui, M; Sano, K; Shibasaki, H; Tomimoto, H1
Matsumoto, Y1
Defelice, T; Franks, AG; Loyd, A; Lu, P; Patel, R1
George, R; Irodi, A; Sathishkumar, D; Thomas, M1
He, L; Lee, J; Mendell-Harary, J; Tao, B; Walker, J; Wickremasingha, P; Wight, D1
Fuertinger, DH; Hoffman, RS; Kotanko, P; Maheshwari, V; Tao, X; Thijssen, S1

Reviews

11 review(s) available for phenytoin and aspirin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Special problems for drugs used in children.
    Southern medical journal, 1976, Volume: 69, Issue:6

    Topics: Aspirin; Child; Diazepam; Drug Therapy; Female; Humans; Infant; Pediatrics; Phenytoin; Primidone

1976
Bioavailability and bioinequivalence of drug formulations in small animals.
    Journal of veterinary pharmacology and therapeutics, 1992, Volume: 15, Issue:2

    Topics: Animals; Aspirin; Biological Availability; Cats; Chloramphenicol; Digoxin; Dogs; Fenbendazole; Mitotane; Oxytetracycline; Penicillins; Phenytoin; Theophylline; Therapeutic Equivalency; Thyroxine

1992
Treatment of preeclampsia and eclampsia.
    Clinical pharmacy, 1992, Volume: 11, Issue:3

    Topics: Antihypertensive Agents; Aspirin; Diazepam; Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclampsia; Pregnancy; Risk Factors

1992
Adverse hematologic effects of drugs.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:4

    Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Aspirin; Blood Platelet Disorders; Drug-Related Side Effects and Adverse Reactions; Female; Glucosephosphate Dehydrogenase Deficiency; Hematologic Diseases; Hematopoiesis; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Serum Sickness; Splenomegaly; Thrombocytopenia; Tranquilizing Agents

1972
Potential environmental chemical hazards. I. Drugs.
    The Science of the total environment, 1972, Volume: 1, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Analgesics; Animals; Aspirin; Carcinogens; Drug-Related Side Effects and Adverse Reactions; Hexachlorophene; Humans; Hydrazines; Isoniazid; Phenacetin; Phenylbutazone; Phenytoin; Procarbazine; Salicylates

1972
Idiosyncratic hematologic reactions to drugs.
    Postgraduate medicine, 1974, Volume: 55, Issue:5

    Topics: Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Macrocytic; Aspirin; Bone Marrow; Bone Marrow Cells; Bone Marrow Examination; Cell Differentiation; Cell Division; Cephalothin; Chloramphenicol; Coombs Test; Drug Hypersensitivity; Erythrocytes; Humans; Methyldopa; Penicillins; Phenytoin; Purpura, Thrombocytopenic; Quinidine

1974
Drug interactions involving cimetidine--mechanisms, documentation, implications.
    Quarterly reviews on drug metabolism and drug interactions, 1984, Volume: 5, Issue:1

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antacids; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifungal Agents; Aspirin; Benzodiazepines; Cimetidine; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Iron; Lidocaine; Pancreas; Phenytoin; Prednisolone; Theophylline; Vitamin B 12

1984
Linear scleroderma in children.
    International journal of dermatology, 1996, Volume: 35, Issue:5

    Topics: Administration, Topical; Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Betamethasone; Child; Dermatologic Agents; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Penicillins; Phenytoin; Scleroderma, Localized; Ticlopidine; Vitamin E

1996
Pre-eclampsia/eclampsia: a literature review.
    The Central African journal of medicine, 1998, Volume: 44, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Eclampsia; Female; Humans; Magnesium Sulfate; Malawi; Phenytoin; Practice Guidelines as Topic; Pregnancy

1998
Ticlopidine and clopidogrel.
    Circulation, 1999, Oct-12, Volume: 100, Issue:15

    Topics: Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angina, Unstable; Aspirin; Bone Marrow Diseases; Carbamazepine; Cardiovascular Diseases; Clopidogrel; Combined Modality Therapy; Coronary Disease; Drug Interactions; Hemorrhage; Humans; Myocardial Infarction; Peripheral Vascular Diseases; Phenytoin; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Receptors, Purinergic P2; Safety; Stents; Theophylline; Thrombolytic Therapy; Ticlopidine

1999

Trials

3 trial(s) available for phenytoin and aspirin

ArticleYear
Reduction of absorption of digoxin, phenytoin and aspirin by activated charcoal in man.
    European journal of clinical pharmacology, 1978, May-31, Volume: 13, Issue:3

    Topics: Adult; Aspirin; Charcoal; Depression, Chemical; Digoxin; Female; Humans; Intestinal Absorption; Male; Phenytoin; Salicylates

1978
Relief of pain of Fabry's disease by diphenylhydantoin.
    Neurology, 1973, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Aspirin; Ceramides; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Galactosidases; Glycolipids; Humans; Lipid Metabolism, Inborn Errors; Male; Pain; Phenytoin; Vitamins

1973
Displacement of phenytoin from plasma binding sites by salicylate.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2

    Topics: Adult; Aspirin; Binding Sites; Drug Interactions; Humans; Male; Phenytoin; Protein Binding; Salicylates; Time Factors

1980

Other Studies

75 other study(ies) available for phenytoin and aspirin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Discovery of 4-aminobutyric acid derivatives possessing anticonvulsant and antinociceptive activities: a hybrid pharmacophore approach.
    Journal of medicinal chemistry, 2007, May-17, Volume: 50, Issue:10

    Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; gamma-Aminobutyric Acid; Hyperalgesia; Mice; Pain; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nervous System Diseases; Rats; Semicarbazones; Structure-Activity Relationship; Touch

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Mass spectrometry of medicines. Quantitative determination by direct probe inlet system mass chromatography.
    Biomedical mass spectrometry, 1978, Volume: 5, Issue:3

    Topics: Aspirin; Barbital; Barbiturates; Caffeine; Mass Spectrometry; Pharmaceutical Preparations; Phenacetin; Phenobarbital; Phenytoin

1978
Plasma albumin concentration and diphenylhydantoin binding in man.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Aged; Aspirin; Blood Protein Electrophoresis; Blood-Brain Barrier; Chromatography, Gas; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Radioligand Assay; Serum Albumin; Ultrafiltration; Uremia

1975
Teratogenicity of therapeutic agents.
    Current problems in pediatrics, 1979, Volume: 10, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Induced; Anesthetics; Animals; Anticoagulants; Antineoplastic Agents; Aspirin; Congenital Abnormalities; Drug Evaluation; Drug Evaluation, Preclinical; Female; Hormones; Humans; Male; Methylmercury Compounds; Phenytoin; Pregnancy; Teratogens; Tetracycline; Thalidomide; Tranquilizing Agents; Trimethadione

1979
The effect of salicylate on phenytoin pharmacokinetics.
    Transactions of the American Neurological Association, 1979, Volume: 104

    Topics: Aspirin; Drug Interactions; Epilepsy; Humans; Phenytoin

1979
The effect of cortisone on the teratogenic action of acetylsalicylic acid and diphenylhydantoin in the mouse.
    Experientia, 1976, Jun-15, Volume: 32, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cleft Palate; Cortisone; Drug Administration Schedule; Drug Synergism; Female; Fetal Death; Mandible; Mice; Phenytoin; Pregnancy

1976
Thyroid dysfunction in female psychiatric patients.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Adult; Age Factors; Aged; Aspirin; Female; Humans; Hypothyroidism; Lithium; Mental Disorders; Middle Aged; Phenytoin; Thyroid Gland; Thyroxine

1976
Computed tomography of the brain, hepatotoxic drugs and high alcohol consumption in male alcoholic patients and a random sample from the general male population.
    Upsala journal of medical sciences, 1992, Volume: 97, Issue:2

    Topics: Adult; Aged; Alcoholism; Analgesics; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Antipyrine; Aspirin; Barbiturates; Benzodiazepines; Brain Damage, Chronic; Cerebral Cortex; Cerebral Ventricles; Cerebral Ventriculography; Chi-Square Distribution; Chlormethiazole; Dextropropoxyphene; Drug Combinations; Drug Interactions; Humans; Ibuprofen; Liver; Liver Function Tests; Male; Middle Aged; Observer Variation; Pancreatic Function Tests; Phenothiazines; Phenytoin; Risk Factors; Sulfamethizole; Sulfamethoxypyridazine; Tomography, X-Ray Computed

1992
Modulation of phenytoin teratogenicity and embryonic covalent binding by acetylsalicylic acid, caffeic acid, and alpha-phenyl-N-t-butylnitrone: implications for bioactivation by prostaglandin synthetase.
    Toxicology and applied pharmacology, 1989, Volume: 97, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Biotransformation; Caffeic Acids; Cinnamates; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; Fetal Resorption; Free Radicals; Mice; Nitrogen Oxides; Phenytoin; Pregnancy; Prostaglandin-Endoperoxide Synthases

1989
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid.
    International journal of clinical pharmacology research, 1989, Volume: 9, Issue:1

    Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid

1989
Inhibition of trimethadione and dimethadione teratogenicity by the cyclooxygenase inhibitor acetylsalicylic acid: a unifying hypothesis for the teratologic effects of hydantoin anticonvulsants and structurally related compounds.
    Toxicology and applied pharmacology, 1989, Mar-01, Volume: 97, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cleft Palate; Dealkylation; Dimethadione; Dose-Response Relationship, Drug; Female; Mice; Oxazoles; Phenytoin; Pregnancy; Trimethadione

1989
Binding of chlorpromazine, phenytoin and aspirin to the erythrocytes and lipoproteins in whole human blood.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:9

    Topics: Aspirin; Chlorpromazine; Erythrocytes; Humans; Lipoproteins; Phenytoin; Protein Binding; Solubility; Ultracentrifugation

1987
The arachidonic acid cascade is involved in the masculinizing action of testosterone on embryonic external genitalia in mice.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:12

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cortisone; Cyproterone; Estradiol; Female; Genitalia, Female; Genitalia, Male; Indomethacin; Male; Mice; Morphogenesis; Phenytoin; Testosterone

1986
Cerebral infarction in juvenile rheumatoid arthritis.
    Clinical neurology and neurosurgery, 1988, Volume: 90, Issue:3

    Topics: Arthritis, Juvenile; Aspirin; Cerebral Infarction; Female; Humans; Infant; Phenytoin; Radiography; Seizures

1988
Drug-induced esophageal strictures.
    Annals of surgery, 1987, Volume: 206, Issue:2

    Topics: Adolescent; Adult; Aged; Ascorbic Acid; Aspirin; Esophageal Stenosis; Female; Humans; Male; Manometry; Middle Aged; Phenytoin; Potassium Chloride; Prospective Studies; Quinidine; Radiography; Tetracycline

1987
Combined phenytoin and salicylate effects on thyroid function tests.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:1

    Topics: Aspirin; Blood Proteins; Carrier Proteins; Drug Interactions; Female; Humans; In Vitro Techniques; Male; Phenytoin; Thyroid Function Tests; Thyroid Hormones

1986
Gastrointestinal dialysis with activated charcoal and cathartic in the treatment of adolescent intoxications.
    Clinical pediatrics, 1985, Volume: 24, Issue:12

    Topics: Adolescent; Adsorption; Adult; Aspirin; Cathartics; Charcoal; Female; Gastric Lavage; Half-Life; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Poisoning

1985
The effect of certain drugs on the plasma protein binding of phenytoin.
    Australian and New Zealand journal of medicine, 1973, Volume: 3, Issue:4

    Topics: Anticonvulsants; Aspirin; Binding Sites; Blood Proteins; Carbamazepine; Dialysis; Diazepam; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Temperature; Thiazines; Ultrafiltration

1973
Evaluation of thyroid status with "effective thyroxine ratio" (E.T.R.).
    Acta endocrinologica, 1974, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Depression, Chemical; Estrogens; Evaluation Studies as Topic; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Male; Menopause; Middle Aged; Phenylbutazone; Phenytoin; Pregnancy; Stimulation, Chemical; Sulfadiazine; Sulfathiazoles; Thyroid Function Tests; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1974
Brain uptake of metabolites and drugs following carotid arterial injections.
    Transactions of the American Neurological Association, 1971, Volume: 96

    Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats

1971
Plasma albumin concentration and binding of diphenylhydantoin in man.
    Transactions of the American Neurological Association, 1974, Volume: 99

    Topics: Adolescent; Adult; Aged; Aspirin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Penicillin G; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin

1974
Effect of certain drugs and environmental agents on microsomal enzyme systems.
    The Science of the total environment, 1972, Volume: 1, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Anisoles; Aspirin; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Intestine, Small; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Morphinans; Nitro Compounds; Oxidoreductases, N-Demethylating; Phenacetin; Phenanthrenes; Phenobarbital; Phenytoin; Rats; Transferases; Trifluoperazine

1972
The management of febrile convulsions.
    Tropical doctor, 1973, Volume: 3, Issue:2

    Topics: Administration, Oral; Aspirin; Child, Preschool; Diazepam; Fever; Humans; Infant; Injections, Intramuscular; Phenobarbital; Phenytoin; Seizures

1973
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:2

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors

1973
Protein binding of drugs in plasma from patients with acute renal failure.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:6

    Topics: Acute Kidney Injury; Aged; Aspirin; Blood Proteins; Female; Humans; In Vitro Techniques; Male; Middle Aged; Phenylbutazone; Phenytoin; Protein Binding; Salicylates; Serum Albumin; Sulfadiazine; Thiopental

1973
[Vitamins and medicines. New and complicated relations].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Mar-30, Volume: 92, Issue:9

    Topics: Arthritis, Rheumatoid; Aspirin; Drug Combinations; Drug Interactions; Epilepsy; Humans; Phenytoin; Primidone; Vitamins

1972
Two dimensional immunoelectrophoresis of human serum proteins for the investigation of protein drugs.
    British journal of pharmacology, 1972, Volume: 45, Issue:1

    Topics: Aspirin; Blood Proteins; Carbon Isotopes; Humans; Immunoelectrophoresis; Iodine Isotopes; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Thyroxine

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine

1972
Aconitine-induced writhing: a method for assessment of analgesic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Aconitum; Analgesics; Animals; Aspirin; Behavior, Animal; Chlorpromazine; Imipramine; Mephenesin; Methaqualone; Methods; Mice; Morphine; Phenoxybenzamine; Phenylbutazone; Phenytoin; Sodium Salicylate

1969
Plasma protein binding of diphenylhydantoin in man.
    Acta pharmacologica et toxicologica, 1971, Volume: 29 Suppl 3

    Topics: Adult; Aspirin; Bilirubin; Blood Proteins; Carbon Isotopes; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Hyperbilirubinemia; Infant, Newborn; Male; Phenylbutazone; Phenytoin; Protein Binding; Sulfisoxazole; Uremia

1971
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried

1970
Seizures and fever.
    Postgraduate medicine, 1971, Volume: 50, Issue:1

    Topics: Acetaminophen; Acidosis, Respiratory; Age Factors; Alkalosis, Respiratory; Aspirin; Brain Diseases; Child, Preschool; Electroencephalography; Fever; Gastrointestinal Diseases; Humans; Hyponatremia; Infant; Phenobarbital; Phenytoin; Prognosis; Respiratory Tract Infections; Seizures; Syncope

1971
Dialysis of drugs against activated charcoal.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3

    Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors

1971
Pure red blood cell aplasia associated with chlorpropamide therapy. Patient summary and review of the literature.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: Adolescent; Adult; Aminosalicylic Acids; Anemia, Aplastic; Aspirin; Barbiturates; Child; Child, Preschool; Chloramphenicol; Chlorpropamide; Colchicine; Female; Glutethimide; Heparin; Humans; Infant; Isoniazid; Male; Middle Aged; Phenytoin; Riboflavin

1969
Interactions between pharmaceutical compounds by thermal methods.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3

    Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K

1969
2,3-benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Analgesia; Animals; Aspirin; Ataxia; Barbiturates; Central Nervous System; Chlordiazepoxide; Chlorpromazine; Exploratory Behavior; Male; Meprobamate; Mice; Morphine; Motor Activity; Muscles; Oxazines; Phenytoin; Pyridones; Rats; Reflex; Seizures

1969
Effect of chlorpromazine on DNA synthesis in a cell free system.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:2

    Topics: Aminopyrine; Animals; Aspirin; Chlorpromazine; Diphenhydramine; DNA; In Vitro Techniques; Liver; Liver Regeneration; Phenytoin; Rats; Subcellular Fractions; Thioridazine; Thymidine

1965
What's new in pediatric dermatology.
    Acta dermato-venereologica. Supplementum, 1981, Volume: 95

    Topics: Anti-Bacterial Agents; Aspirin; Epidermolysis Bullosa; Hexachlorocyclohexane; Humans; Impetigo; Infant; Mucocutaneous Lymph Node Syndrome; Nevus; Phenytoin; Scabies; Skin Diseases; Skin Neoplasms

1981
Definition and implications of dose-dependent kinetics in clinical medicine.
    Drug metabolism reviews, 1983, Volume: 14, Issue:6

    Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Ethanol; Humans; Kinetics; Lidocaine; Pharmaceutical Preparations; Phenytoin; Valproic Acid

1983
Use of ibuprofen in unusual circumstances.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersensitivity; Drug Interactions; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Kidney; Kinetics; Lithium; Liver; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Phenytoin; Platelet Aggregation; Prostaglandins E; Warfarin

1984
[Direct and indirect parameters of free thyroxine. I. Method, quality control and in vitro experiments on storage of samples and effect of drugs].
    Nuklearmedizin. Nuclear medicine, 1983, Volume: 22, Issue:6

    Topics: Aspirin; Blood Preservation; Drug Interactions; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Radioimmunoassay; Thyroxine

1983
Folate supplements and phenytoin-salicylate interaction.
    Neurology, 1983, Volume: 33, Issue:1

    Topics: Adult; Aspirin; Drug Interactions; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenytoin; Seizures

1983
Early reports on drug interactions.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2

    Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine

1983
The effects of salicylate on the pharmacokinetics of phenytoin.
    Neurology, 1981, Volume: 31, Issue:3

    Topics: Aspirin; Female; Humans; Kidney; Kinetics; Male; Phenytoin; Protein Binding; Saliva

1981
Effects of aspirin on salivary and serum phenytoin kinetics in healthy subjects.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:2

    Topics: Adult; Aspirin; Drug Interactions; Female; Humans; Male; Phenytoin; Protein Binding; Saliva; Time Factors

1980
Phenytoin-salicylate interaction.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:1

    Topics: Adult; Aspirin; Blood Proteins; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Phenytoin; Protein Binding; Saliva

1981
'MacDope': a simulation of drug disposition in the human body: applications in clinical pharmacokinetics.
    British journal of clinical pharmacology, 1980, Volume: 10, Issue:6

    Topics: Aspirin; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Liver; Male; Models, Biological; Pharmaceutical Preparations; Phenytoin; Protein Binding

1980
Aspirin and anticonvulsant interaction.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:1

    Topics: Animals; Aspirin; Carbamazepine; Disease Models, Animal; Drug Synergism; Electroshock; Female; Male; Phenobarbital; Phenytoin; Rats; Seizures

1995
DETERMINATION OF THYROXINE UTILIZING THE PROPERTY OF PROTEIN-BINDING.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Aspirin; Bilirubin; Blood Chemical Analysis; Blood Proteins; Cholesterol; Glucose; Heparin; Hyperthyroidism; Hypothyroidism; Iodides; Iodine; Iodine Isotopes; Mercury; Oxalates; Phenytoin; Potassium; Research; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine

1964
DRUG DOSAGE. A REVIEW OF A PROBLEM IN PEDIATRICS.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Aspirin; Child; Digitoxin; Digoxin; Dosage Forms; Drug Therapy; Humans; Infant; Pediatrics; Phenobarbital; Phenytoin; Sulfadiazine; Thyroid Hormones

1964
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine

1965
Paroxysmal dysarthria and ataxia after midbrain infarction.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Aged; Anticoagulants; Aspirin; Cerebellum; Diplopia; Dysarthria; Gait Ataxia; Humans; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Neural Pathways; Parietal Lobe; Phenytoin; Recurrence; Sensation Disorders; Thalamus; Tomography, Emission-Computed, Single-Photon

2004
[A pharmacokinetic analysis in a patient with acute drug poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2005, Volume: 18, Issue:4

    Topics: Acute Disease; Aspirin; Benzodiazepines; Humans; Pharmacokinetics; Phenytoin; Poisoning

2005
Livedo racemosa, secondary to drug-induced systemic lupus erythematosus.
    Dermatology online journal, 2010, Nov-15, Volume: 16, Issue:11

    Topics: Adult; Aspirin; Autoantibodies; Histones; Humans; Livedo Reticularis; Lupus Erythematosus, Systemic; Male; Phenytoin; Skin Diseases, Vascular; Smoking

2010
PHACES syndrome with moyamoya vasculopathy - a case report.
    Dermatology online journal, 2013, Aug-15, Volume: 19, Issue:8

    Topics: Anticonvulsants; Aortic Coarctation; Aspirin; Brain Ischemia; Child, Preschool; Eye Abnormalities; Female; Humans; Moyamoya Disease; Neurocutaneous Syndromes; Phenytoin; Platelet Aggregation Inhibitors; Seizures

2013
Lack of effect of colesevelam HCl on the single-dose pharmacokinetics of aspirin, atenolol, enalapril, phenytoin, rosiglitazone, and sitagliptin.
    Diabetes research and clinical practice, 2014, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Allylamine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticonvulsants; Antihypertensive Agents; Area Under Curve; Aspirin; Atenolol; Colesevelam Hydrochloride; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Phenytoin; Pyrazines; Rosiglitazone; Sitagliptin Phosphate; Thiazolidinediones; Tissue Distribution; Triazoles; Young Adult

2014
A model-based analysis of phenytoin and carbamazepine toxicity treatment using binding-competition during hemodialysis.
    Scientific reports, 2020, 07-09, Volume: 10, Issue:1

    Topics: Aspirin; Binding, Competitive; Carbamazepine; Humans; Ibuprofen; Models, Chemical; Phenytoin; Protein Binding; Renal Dialysis

2020