phenytoin has been researched along with ascorbic acid in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (64.86) | 18.7374 |
| 1990's | 1 (2.70) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 9 (24.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bharathi, K; Prasad, KV; Prasanthi, G | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Pálosi, E; Szeberényi, S; Szporny, L | 1 |
| Colombetti, LG | 1 |
| Chadwick, D; Fairhurst, E; Reynolds, EH; Ridge, BD | 1 |
| Albertucci, M; Bailey, RT; Bonavina, L; DeMeester, TR; McChesney, L; Schwizer, W | 1 |
| Dubick, MA; Keen, CL | 1 |
| Granatek, AP; Mihotic, MM; Prasad, VK | 1 |
| Bonollo, L | 1 |
| Erdmann, E; Schoner, W | 1 |
| Dill, RE | 1 |
| Oldendorf, WH | 1 |
| Enwonwu, CO; Morgan, AF; Stambaugh, RV | 1 |
| Brown, D; Neill, LT; Overall, JE; Williams, JD | 1 |
| Hrbek, J; Komenda, S; Macáková, J; Siroká, A | 1 |
| Flessa, HC; Sigell, LT | 1 |
| Stedman, DB; Welsch, F | 1 |
| Alberts, DS; Dorr, RT; Peng, YM | 1 |
| Ba, TT; Carrel, R; Chapman, MK | 1 |
| Charpentier, C; Dagbovie, K; Johnstone, RA; Larregue, M; Lemonnier, A | 1 |
| Begg, E; O'Shea, K; Wade, D; Williams, K | 1 |
| Al-Janabi, NY; Al-Tai, SA; Al-Ubaidy, SS | 1 |
| Gratzl, O; Landolt, H; Langemann, H; Probst, A | 1 |
| CRITZ, JB; WITHROW, TJ | 1 |
| BORGLIN, K; HARDAL, B; RAYNER, S | 1 |
| Buffaloe, WJ; Dunham, RM; Rose, JH | 1 |
| Abdulla, MM; El Desoky, ES | 1 |
| WEINLAND, WL | 1 |
| Abela, D; Howe, AM; Oakes, DA; Webster, WS | 1 |
| Akpan, HD; Akpanabiatu, MI; Ekaidem, IS; Uboh, FE; Usoh, IF | 1 |
| Gholami, M; Motealleh, B; Rezaeian, I; Salehpour, A; Zahedi, P; Zarandi, MA | 1 |
1 review(s) available for phenytoin and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for phenytoin and ascorbic acid
| Article | Year |
|---|---|
Drug treatment of anxiety and depression in detoxified alcoholic patients.
Topics: Alcoholism; Amitriptyline; Analysis of Variance; Anxiety; Ascorbic Acid; Chlordiazepoxide; Depression; Dose-Response Relationship, Drug; Educational Status; Humans; Intelligence Tests; Mesoridazine; Phenytoin; Psychological Tests; Substance Withdrawal Syndrome; Vitamin B Complex | 1973 |
On the acute effect of drugs on artificial conditioned verbal associations.
Topics: Adolescent; Adult; Amitriptyline; Analysis of Variance; Ascorbic Acid; Association; Chlordiazepoxide; Conditioning, Psychological; Diazepam; Female; Humans; Male; Meprobamate; Nortriptyline; Phenytoin; Placebos; Pyridoxine; Riboflavin; Statistics as Topic; Thiamine; Verbal Behavior | 1970 |
34 other study(ies) available for phenytoin and ascorbic acid
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction.
Topics: Absorption; Analgesics; Animals; Anticonvulsants; Antioxidants; Chemistry Techniques, Synthetic; Drug Design; Male; Mice; Pyridines; Rats | 2013 |
Effects of 3-trifluoromethyl-alpha-ethylbenzhydrol (RGH-3332), a new enzyme inducer, on the microsomal drug metabolism. Part I.
Topics: Animals; Ascorbic Acid; Benzhydryl Compounds; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine; Female; Hydroquinones; Hypnotics and Sedatives; Microsomes, Liver; Muscle Relaxants, Central; Pentylenetetrazole; Pharmaceutical Preparations; Phenytoin; Rats | 1978 |
The use of radiopharmaceuticals in the visualization of the endocrine gland.
Topics: Adrenal Gland Diseases; Animals; Ascorbic Acid; Carbon Radioisotopes; Cholesterol; Dichlorodiphenyldichloroethane; Estradiol; Humans; Iodine Radioisotopes; Pancreatic Diseases; Parathyroid Diseases; Phenytoin; Radionuclide Imaging; Selenomethionine; Technetium; Thyroid Diseases | 1977 |
Ascorbic acid concentrations in human plasma and cerebrospinal fluid [proceedings].
Topics: Ascorbic Acid; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1976 |
Drug-induced esophageal strictures.
Topics: Adolescent; Adult; Aged; Ascorbic Acid; Aspirin; Esophageal Stenosis; Female; Humans; Male; Manometry; Middle Aged; Phenytoin; Potassium Chloride; Prospective Studies; Quinidine; Radiography; Tetracycline | 1987 |
Alterations in tissue trace element and ascorbic acid metabolism in phenytoin-fed rats and mice.
Topics: Administration, Oral; Animals; Ascorbic Acid; Body Weight; Kidney; Liver; Male; Mice; Mixed Function Oxygenases; Organ Size; Phenytoin; Rats; Rats, Inbred Strains; Species Specificity; Spectrophotometry, Atomic; Trace Elements | 1985 |
Physical compatibility and chemical stability of cephapirin sodium in combination with non-antibiotic drugs in large-volume parenteral solutions. II.
Topics: Acetamides; Aminophylline; Ascorbic Acid; Barbiturates; Bicarbonates; Calcium Chloride; Cephalosporins; Chemical Phenomena; Chemistry; Diphenhydramine; Drug Combinations; Drug Incompatibility; Drug Stability; Epinephrine; Ergonovine; Heparin; Hydrocortisone; Hydrogen-Ion Concentration; Metaraminol; Nitrofurantoin; Norepinephrine; Phenytoin; Pyridines; Solutions; Succinylcholine; Sulfadiazine; Sulfides; Sulfisoxazole; Thiopental; Vitamins; Warfarin | 1974 |
[Influence of ascorbic acid and nicotinamide onthe body weight of rats treated with diphenylhydantoin].
Topics: Animals; Ascorbic Acid; Body Weight; Niacinamide; Phenytoin; Rats | 1969 |
Ouabain-receptor interactions in (Na+ plus K+)-ATPase preparations. IV. The molecular structure of different cardioactive steroids and other substances and their affinity to the glycoside receptor.
Topics: Adenosine Triphosphatases; Animals; Ascorbic Acid; Binding Sites; Brain; Cardiac Glycosides; Cattle; Chemical Phenomena; Chemistry; Digoxin; Drug Interactions; Kinetics; Molecular Conformation; Ouabain; Phenytoin; Potassium; Prednisolone; Prednisone; Receptors, Drug; Sodium; Stimulation, Chemical; Structure-Activity Relationship; Tritium | 1974 |
Discrepancy of adrenal responses in diphenylhydantoin-treated rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Ascorbic Acid; Corticosterone; Phenytoin; Rats; Stress, Physiological | 1966 |
Brain uptake of metabolites and drugs following carotid arterial injections.
Topics: Acetates; Amino Acids; Animals; Antipyrine; Ascorbic Acid; Aspirin; Barbiturates; Blood-Brain Barrier; Brain; Caffeine; Chloroquine; Cyanides; Ethanol; Imipramine; Lactates; Mescaline; Morphine; Neurotransmitter Agents; Nicotine; Penicillin G; Pharmaceutical Preparations; Phenytoin; Procaine; Pyruvates; Rats | 1971 |
Ascorbic acid deficiency associated with dilantin hyperplasia.
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenytoin | 1973 |
Drug interactions with anticoagulants.
Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Anticoagulants; Ascorbic Acid; Barbiturates; Blood Coagulation; Blood Coagulation Tests; Cardiac Glycosides; Chlordiazepoxide; Chlorothiazide; Contraceptives, Oral; Diazepam; Dogs; Drug Antagonism; Epinephrine; Ethchlorvynol; Glucagon; Haloperidol; Humans; Methylphenidate; Phenethylamines; Phenylbutazone; Phenytoin; Quinolines; Salicylates; Steroids; Substance-Related Disorders; Tetanus Toxoid; Tolbutamide; Xanthines | 1970 |
Inhibition of metabolic cooperation between Chinese hamster V79 cells by structurally diverse teratogens.
Topics: Animals; Ascorbic Acid; Cell Communication; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Ethylene Glycols; Lung; Mutation; Phenytoin; Saccharin; Teratogens; Tetradecanoylphorbol Acetate; Warfarin | 1984 |
Bleomycin compatibility with selected intravenous medications.
Topics: Aminophylline; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Ascorbic Acid; Bleomycin; Diazepam; Drug Incompatibility; Heparin; Infusions, Parenteral; Phenytoin; Terbutaline | 1982 |
Gingival aberrations in Dilantin-treated guinea pigs.
Topics: Animals; Ascorbic Acid; Female; Gingiva; Gingival Hyperplasia; Guinea Pigs; Phenytoin | 1983 |
Prolidase deficiency with iminodipeptiduria: biochemical investigations and first results of attempted therapy.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Dipeptidases; Dipeptides; Erythrocytes; Female; Humans; Hydroxyproline; Manganese; Phenytoin; Proline | 1981 |
Effects of phenytoin, phenobarbital, and ascorbic acid on misonidazole elimination.
Topics: Adult; Ascorbic Acid; Drug Interactions; Female; Humans; Kinetics; Male; Misonidazole; Nitroimidazoles; Phenobarbital; Phenytoin; Protein Binding | 1983 |
Effect of phenytoin on mitotic activity of gingival tissue and cultured fibroblasts.
Topics: Animals; Ascorbic Acid; Autoradiography; Cells, Cultured; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Mitosis; Phenytoin; Rats | 1981 |
Levels of water-soluble antioxidants in astrocytoma and in adjacent tumor-free tissue.
Topics: Adult; Aged; Antioxidants; Artifacts; Ascorbic Acid; Astrocytoma; Biopsy; Brain Chemistry; Brain Edema; Brain Neoplasms; Combined Modality Therapy; Cysteine; Dexamethasone; DNA, Neoplasm; Female; Free Radicals; Glioblastoma; Glutathione; Humans; Male; Middle Aged; Necrosis; Neoplasm Proteins; Oxidation-Reduction; Oxidative Stress; Phenytoin; Solubility; Stereotaxic Techniques; Tomography, X-Ray Computed; Uric Acid; Water | 1994 |
ADRENOCORTICAL BLOCKADE AND THE TRANSAMINASE RESPONSE TO EXERCISE.
Topics: Adrenal Glands; Adrenalectomy; Ascorbic Acid; Aspartate Aminotransferases; Metabolism; Muscles; Myocardium; Pharmacology; Phenytoin; Physical Exertion; Rats; Research; Swimming; Transaminases | 1965 |
[TREATMENT WITH DYPHENYL HYDANTOINATE IN CORRELATION TO STATE OF GINGIVA AND BLOOD-LEVEL OF ASCORBIC ACID].
Topics: Ascorbic Acid; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Toxicology | 1965 |
A study of the effect of vitamin C and of an antihistaminic drug on gingival hyperplasia occurring in patients receiving diphenylhydantoin sodium.
Topics: Anti-Allergic Agents; Ascorbic Acid; Gingiva; Gingival Hyperplasia; Histamine H1 Antagonists; Phenytoin; Sodium; Vitamins | 1961 |
Studying long-term effect of phenytoin either alone or combined with ascorbic acid on the anesthetic effect of urethane in rats.
Topics: Administration, Oral; Anesthetics, Intravenous; Animals; Anticonvulsants; Ascorbic Acid; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Injections, Intraperitoneal; Intubation, Gastrointestinal; Male; Phenytoin; Postural Balance; Rats; Time Factors; Urethane | 2004 |
[Diphenylhydantoin and vitamin C metabolism].
Topics: Ascorbic Acid; Carbohydrate Metabolism; Humans; Hydantoins; Metabolism; Phenytoin; Vitamins | 1950 |
Maternal antioxidant supplementation does not reduce the incidence of phenytoin-induced cleft lip and related malformations in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Antioxidants; Ascorbic Acid; Body Weight; Cleft Lip; Coenzymes; Diet; Eating; Female; Male; Maxilla; Phenytoin; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Ubiquinone; Vitamin E | 2005 |
Urate synthesis and oxidative stress in phenytoin hepatotoxicity: the role of antioxidant vitamins.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Folic Acid; Liver; Oxidative Stress; Phenytoin; Rats, Wistar; Superoxides; Uric Acid; Vitamin E; Xanthine Oxidase | 2014 |
Drug release, cell adhesion and wound healing evaluations of electrospun carboxymethyl chitosan/polyethylene oxide nanofibres containing phenytoin sodium and vitamin C.
Topics: Animals; Ascorbic Acid; Cell Adhesion; Chitosan; Drug Liberation; Male; Nanofibers; Phenytoin; Polyethylene Glycols; Rats; Rats, Wistar; Wound Healing | 2015 |