phenytoin has been researched along with aminopyrine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (64.52) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caron, G; Ermondi, G | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Akamatsu, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bender, AD; Richey, DP | 1 |
| Bell, GD; Cartwright, S; Chaplain, S; Henry, DA; Kitchingman, G; Langman, MJ; Sharpe, G | 1 |
| Humphries, TJ | 1 |
| Fermus, R; Figurski, R; Hański, W | 1 |
| Greengard, P; Quinn, GP; Reid, MB | 1 |
| Cockrill, BL; Platt, DS | 1 |
| Röttger, HJ; Windorfer, A | 1 |
| Gajewska, M | 1 |
| Bacci, MC; Bianchi, C; Bonardi, G; Coppi, G; Molino, C; Tomasi, L; Vidi, A | 1 |
| Bianchi, C; Bonardi, G | 1 |
| Trautmann, A | 1 |
| Remmer, H | 1 |
| Asahi, K; Iizuka, H; Okabe, Y; Yanagida, T | 1 |
| Becker, BA; Eling, TE; Fouts, JR; Harbison, RD | 1 |
| Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K | 1 |
| Hinz, JE; Pisciotta, AV; Ziebert, AP | 1 |
| Horiuchi, M; Ibii, N; Yamamoto, K | 1 |
| D'Arcy, PF | 1 |
| Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D | 1 |
| Adatia, MR; Rao, GS; Siew, C; Wortel, JP | 1 |
| Boucher, BA; Hanes, SD | 1 |
| ZAKHARIIA, EA; ZAPADNIUK, VI | 1 |
4 review(s) available for phenytoin and aminopyrine
| Article | Year |
|---|---|
Pharmacokinetic consequences of aging.
Topics: Adult; Aged; Aging; Aminopyrine; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Blood Proteins; Digoxin; Disease; Female; Humans; Intestinal Absorption; Kidney; Kinetics; Male; Middle Aged; Pharmaceutical Preparations; Phenytoin; Protein Binding; Rats | 1977 |
Clinical implications of drug interactions with the cytochrome P-450 enzyme system associated with omeprazole.
Topics: Aminopyrine; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Humans; Omeprazole; Phenytoin; Propranolol; Theophylline; Warfarin | 1991 |
Vaccine-drug interactions.
Topics: Aminopyrine; BCG Vaccine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Influenza Vaccines; Pertussis Vaccine; Phenytoin; Risk; Theophylline; Vaccination; Vaccines | 1984 |
Pharmacokinetic alterations after severe head injury. Clinical relevance.
Topics: Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Blood-Brain Barrier; Craniocerebral Trauma; Drug Interactions; Humans; Hypnotics and Sedatives; Lorazepam; Pentobarbital; Phenytoin; Thiopental | 1998 |
27 other study(ies) available for phenytoin and aminopyrine
| Article | Year |
|---|---|
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
The [14C]-aminopyrine breath test. A comparison of different forms of analysis.
Topics: Aminopyrine; Breath Tests; Carbon Dioxide; Epilepsy; Glucaric Acid; Glutethimide; Humans; Liver Diseases; Phenytoin; Time Factors | 1979 |
Granulomatous lung disease in children by aspiration of medications.
Topics: Administration, Oral; Aminopyrine; Child; Cholestyramine Resin; Female; Foreign-Body Reaction; Granuloma; Humans; Hydroxybenzoates; Infant; Infant, Newborn; Lung; Male; Nitrofurans; Phenobarbital; Phenytoin; Pneumonia, Aspiration | 1987 |
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine | 1966 |
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics | 1969 |
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography].
Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature | 1974 |
Complexometric determination of various diazole derivatives with cupric picrate.
Topics: Aminopyrine; Antipyrine; Azoles; Copper; Histamine; Hydrogen-Ion Concentration; Imidazoles; Indicators and Reagents; Methods; Metronidazole; Phenylbutazone; Phenytoin; Picrates; Structure-Activity Relationship; Tolazoline | 1972 |
Experimental models for the in vivo evaluation of enzyme induction properties of drugs.
Topics: Acetanilides; Amides; Aminopyrine; Amphetamine; Aniline Compounds; Animals; Central Nervous System; Codeine; Cyclohexanecarboxylic Acids; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Hexobarbital; Male; Meperidine; Mice; Oxotremorine; Pentobarbital; Phenacetin; Phenytoin; Rabbits; Rats; Strychnine; Tolbutamide; Tremorine; Zoxazolamine | 1973 |
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. General pharmacological properties.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Blood Glucose; Cardiovascular System; Codeine; Diuresis; Edema; Enzyme Induction; Female; Male; Mice; Nervous System; Pepsinogens; Phenylbutazone; Phenytoin; Pyrazoles; Rats; Terpenes; Uric Acid | 1972 |
[Dialysis of drugs and poisons. 2].
Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine | 1972 |
[Changes of drug effects caused by their metabolism in the liver].
Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental | 1971 |
[Influence of food deprivation on efficacy and toxicity of drugs in mice].
Topics: Acetates; Aminopyrine; Analgesics; Animals; Anticonvulsants; Blood Glucose; Blood Proteins; Body Weight; Carrageenan; Cholesterol; Citrates; Female; Male; Methylcellulose; Mice; Oxyphenbutazone; Pectins; Pentobarbital; Pentylenetetrazole; Pharmacology; Phenytoin; Starvation; Time Factors; Toxicology | 1969 |
Diphenylhydantoin effect on neonatal and adult rat hepatic drug metabolism.
Topics: Age Factors; Aminopyrine; Aniline Compounds; Animals; Animals, Newborn; Benzoates; Benzopyrenes; Benzphetamine; Body Weight; Cytochromes; Hexobarbital; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Microsomes, Liver; Mixed Function Oxygenases; Nitrophenols; Organ Size; Phenytoin; Proteins; Rats | 1970 |
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried | 1970 |
Effect of chlorpromazine on DNA synthesis in a cell free system.
Topics: Aminopyrine; Animals; Aspirin; Chlorpromazine; Diphenhydramine; DNA; In Vitro Techniques; Liver; Liver Regeneration; Phenytoin; Rats; Subcellular Fractions; Thioridazine; Thymidine | 1965 |
[Pharmacology of a 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), a new sleep-inducer (III). Behavioral study on interactions of 450191-S and other drugs in mice].
Topics: Aminopyrine; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzodiazepines; Central Nervous System; Central Nervous System Agents; Haloperidol; Hypnotics and Sedatives; Imipramine; Male; Mice; Pentylenetetrazole; Phenytoin; Reserpine; Triazoles | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
Gingiva as a site for xenobiotic metabolism in rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Gingiva; Male; Pharmaceutical Preparations; Phenytoin; Rats; Rats, Inbred Strains; Tripelennamine | 1984 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology | 1964 |