phenytoin and amiloride

phenytoin has been researched along with amiloride in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's1 (6.67)18.2507
2000's5 (33.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blackard, WG; Kikuchi, M; Rabinovitch, A; Renold, AE1
De Sousa, RC1
Akaike, N; Takahashi, K; Wakamori, M1
de Sousa, RC; Grosso, A1
Ilani, A; Lichtstein, D; Yachin, S1
Nencini, P; Pasquarelli, V1
Hescheler, J; Lingle, CJ; Nakashima, YM; Pereverzev, A; Schneider, T; Todorovic, SM1

Reviews

1 review(s) available for phenytoin and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

14 other study(ies) available for phenytoin and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
An effect of hyposmolarity on insulin release in vitro.
    The American journal of physiology, 1975, Volume: 228, Issue:3

    Topics: Amiloride; Amylases; Animals; Atropine; Calcium; Choline; Colchicine; Diazoxide; Epinephrine; Glucagon; Glucose; Hypotonic Solutions; Imidazoles; In Vitro Techniques; Insulin; Insulin Secretion; Male; Osmolar Concentration; Ouabain; Pancreas; Phentolamine; Phenytoin; Propranolol; Rats; Sorbitol; Tolbutamide; Trypsin Inhibitors; Vinblastine

1975
[Sodium and water transport mechanisms in amphibian epithelial cells and isolated renal tubules].
    Journal de physiologie, 1975, Volume: 71, Issue:1

    Topics: Aldosterone; Amiloride; Amphibians; Amphotericin B; Animals; Biological Transport; Catecholamines; Epithelial Cells; Epithelium; Kidney Tubules; Metals, Rare Earth; Microtubules; Models, Biological; Nucleotides, Cyclic; Osmolar Concentration; Ouabain; Oxygen Consumption; Phenytoin; Pituitary Hormones; Sodium; Thermodynamics; Vasopressins; Water

1975
Hippocampal CA1 pyramidal cells of rats have four voltage-dependent calcium conductances.
    Neuroscience letters, 1989, Sep-25, Volume: 104, Issue:1-2

    Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Electric Conductivity; Gadolinium; Hippocampus; Kinetics; Lanthanum; Neurons; Nicardipine; Octanols; Phenytoin; Pyramidal Tracts; Rats; Tetrodotoxin

1989
Effects of diphenylhydantoin on transport processed in frog skin (Rana ridibunda).
    Experientia, 1973, Sep-15, Volume: 29, Issue:9

    Topics: Amiloride; Amphotericin B; Animals; Anura; Biological Transport; Membrane Potentials; Oxytocin; Phenytoin; Ranidae; Skin; Sodium

1973
Comparison between bretylium and diphenylhydantoin interaction with mucosal sodium-channels.
    Biochimica et biophysica acta, 1984, Nov-07, Volume: 777, Issue:2

    Topics: Amiloride; Animals; Bretylium Compounds; Bretylium Tosylate; Drug Interactions; Electric Conductivity; Hydrogen-Ion Concentration; Ion Channels; Membrane Potentials; Mucous Membrane; Oxytocin; Phenytoin; Rana ridibunda; Skin; Sodium

1984
Influences of tetrodotoxin, amiloride, phenytoin, aconitine, tetraethylammonium on ACTH-an isoproterenol-mediated lipolysis in isolated rat adipocytes.
    Pharmacological research communications, 1982, Volume: 14, Issue:3

    Topics: Aconitine; Adipose Tissue; Adrenocorticotropic Hormone; Amiloride; Animals; Electrolytes; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenytoin; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Tetrodotoxin

1982
Properties of Ba2+ currents arising from human alpha1E and alpha1Ebeta3 constructs expressed in HEK293 cells: physiology, pharmacology, and comparison to native T-type Ba2+ currents.
    Neuropharmacology, 1998, Volume: 37, Issue:8

    Topics: Amiloride; Barium; Calcium Channels; Cell Line; Ganglia, Spinal; Humans; Ion Channels; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phenytoin

1998