phenytoin and alprenolol

phenytoin has been researched along with alprenolol in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's0 (0.00)18.2507
2000's7 (36.84)29.6817
2010's6 (31.58)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Gozalbes, R; Pineda-Lucena, A1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Lovell, RR1
Aberg, A; Ulvenstam, G; Vedin, A; Wilhelmsson, C1
Heeg, E; Reuter, N1
Ruutu, T1

Other Studies

19 other study(ies) available for phenytoin and alprenolol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Arrhythmia prophylaxis: Long-term suppressive medication.
    Circulation, 1975, Volume: 52, Issue:6 Suppl

    Topics: Acute Disease; Aged; Alprenolol; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Coronary Disease; Death, Sudden; Female; Humans; Male; Middle Aged; Myocardial Infarction; Phenytoin; Procainamide; Ventricular Fibrillation

1975
[Indications for long term treatment of ventricular arrhythmias].
    Lakartidningen, 1974, Dec-11, Volume: 71, Issue:50

    Topics: Alprenolol; Arrhythmias, Cardiac; Death, Sudden; Digitalis Glycosides; Electrocardiography; Humans; Long-Term Care; Phenytoin; Practolol; Procainamide; Quinidine

1974
[Action of antiarrhythmic and -receptor blocking drugs on functional refractory period and contractility of electrically stimulated guinea-pig atria].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Atrial Function; Drug Interactions; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Phenytoin; Procainamide; Propranolol; Quinidine; Reserpine; Sparteine; Sympatholytics; Time Factors; Verapamil

1971
Effect of antiarrhythmic and diuretic agents on phagocytosis and bacterial killing by human neutrophilic leukocytes.
    Annales medicinae experimentalis et biologiae Fenniae, 1972, Volume: 50, Issue:1

    Topics: 1-Propanol; Alprenolol; Amino Alcohols; Anti-Arrhythmia Agents; Blood Bactericidal Activity; Cell Membrane Permeability; Culture Media; Diuretics; Humans; Hydrogen-Ion Concentration; Lidocaine; Neutrophils; Ouabain; Phagocytosis; Phenytoin; Staphylococcus; Stimulation, Chemical; Time Factors

1972