phenytoin has been researched along with allopurinol in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (23.68) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 7 (18.42) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 3 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Christensen, LK; Hansen, JM | 1 |
| Bircher, J; Brandes, A; Compagnone, D; Hille, H; Münch, B; Ullrich, D | 1 |
| Allen, SG; Heng, MC | 1 |
| Ito, Y; Iwaki, M; Ogiso, T; Tsunekawa, K | 1 |
| Hachet, E | 1 |
| Billings, RE; Milton, SG | 1 |
| Kumar, KL; Reuler, JB | 1 |
| Passananti, GT; Vessell, ES | 1 |
| Avgar, DM; Ishay, JS; Noy-Man, Y; Ribak, JP; Shirin, ME | 1 |
| Bukowskyj, M; Munt, PW; Nakatsu, K | 1 |
| Chiba, K; Ishizaki, T; Yokochi, A; Yokochi, K | 1 |
| Chang, NC; Chen, YH; Dai, YS; Lin, MS; Pwu, RF | 1 |
| Hanken, I; Sander, CA; Schimmer, M | 1 |
| Chen, YC; Chiu, HC; Chu, CY | 1 |
| Chanprapaph, K; Rattanakaemakorn, P; Vachiramon, V; Wongkitisophon, P | 1 |
| Choonhakarn, C; Kongbunkiat, K; Limpawattana, P | 1 |
| Akpan, HD; Akpanabiatu, MI; Ekaidem, IS; Uboh, FE; Usoh, IF | 1 |
| Cheng, CY; Cheng, FJ; Chuang, PC; Huang, YS; Pan, HY; Syu, FK | 1 |
| Chen, WW; Chien, MY; Chiou, MH; Chu, CY; Huang, PW | 1 |
| Chen, C; Chen, X; Chi, L; Guo, X; Guo, Z; He, J; Liang, J; Wei, L; Ye, X; Zheng, Y; Zhou, W | 1 |
| Abdullah, NH; Kristummoonthy, P; Lee, CS; Tee, CT | 1 |
4 review(s) available for phenytoin and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide | 1977 |
Utility of clinical chemical determinations of drug concentrations in biological fluids.
Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays | 1971 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline | 1984 |
34 other study(ies) available for phenytoin and allopurinol
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations.
Topics: Adolescent; Adult; Age Factors; Allopurinol; Caffeine; Child; Cimetidine; Drug Interactions; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosis; Male; Phenytoin; Smoking; Theophylline | 1992 |
Efficacy of cyclophosphamide in toxic epidermal necrolysis. Clinical and pathophysiologic aspects.
Topics: Adult; Aged; Allopurinol; Ampicillin; Basement Membrane; Cell Membrane; Chlorpropamide; Cyclophosphamide; Drug Therapy, Combination; Epidermis; Humans; Immunohistochemistry; Infusions, Intravenous; Keratinocytes; Male; Microscopy, Electron; Middle Aged; Phenytoin; Stevens-Johnson Syndrome; T-Lymphocyte Subsets | 1991 |
Drug interaction between phenytoin and allopurinol.
Topics: Administration, Oral; Allopurinol; Animals; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Kidney; Liver; Male; Phenytoin; Rats; Rats, Inbred Strains; Regional Blood Flow | 1990 |
[Cataracts].
Topics: Adrenal Cortex Hormones; Allopurinol; Amiodarone; Animals; Antimalarials; Antineoplastic Agents; Antipsychotic Agents; Cataract; Cholinesterase Inhibitors; Contraceptives, Oral, Hormonal; Deferoxamine; Humans; Mercury; Phenothiazines; Phenytoin; Prednisone | 1985 |
Conversion of phenytoin to reactive metabolites in rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Radioisotopes; Hydroxylation; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenytoin; Rats; Rats, Inbred Strains; Superoxides; Xanthine Oxidase | 1986 |
Drug fever.
Topics: Allopurinol; Anti-Bacterial Agents; Body Temperature Regulation; Drug Hypersensitivity; Fever; Humans; Interleukin-1; Isoniazid; Methyldopa; Phenytoin; Procainamide; Quinidine | 1986 |
Hornets (Hymenoptera, Vespinae) living at simulated high altitude: the combined effects of low pressure, hypoxia, light, hyperkinesis and drugs on behavior and survival.
Topics: Allopurinol; Altitude; Animals; Atmospheric Pressure; Behavior, Animal; Female; Fertility; Humans; Hymenoptera; Hyperkinesis; Hypoxia; Light; Male; Mortality; Phenytoin; Wasps; Xanthines | 1982 |
Phenytoin--allopurinol interaction: Michaelis--Menten kinetic parameters of phenytoin with and without allopurinol in a child with Lesch--Nyhan syndrome.
Topics: Adolescent; Allopurinol; Body Weight; Child; Child, Preschool; Drug Interactions; Humans; Kinetics; Lesch-Nyhan Syndrome; Male; Phenytoin | 1982 |
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study.
Topics: Adult; Allopurinol; Analgesics, Non-Narcotic; Anticonvulsants; Antimetabolites; Carbamazepine; Case-Control Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Phenytoin; Risk Assessment; Stevens-Johnson Syndrome; Taiwan | 2005 |
Basic measures and systemic medical treatment of patients with toxic epidermal necrolysis.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anticonvulsants; Bacterial Infections; Ciprofloxacin; Drug Combinations; Female; Folic Acid; Gout Suppressants; Humans; Hydroxocobalamin; Lidocaine; Male; Middle Aged; Phenytoin; Prednisone; Pyridoxine; Stevens-Johnson Syndrome; Superinfection; Survival Rate; Trimethoprim, Sulfamethoxazole Drug Combination | 2010 |
Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Infective Agents; Anticonvulsants; Child; Dapsone; Drug Eruptions; Eosinophilia; Female; Gout Suppressants; Humans; Male; Middle Aged; Pancytopenia; Phenytoin; Prognosis; Retrospective Studies; Risk Factors; Taiwan; Young Adult | 2010 |
Six-year retrospective review of drug reaction with eosinophilia and systemic symptoms.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-HIV Agents; Anti-Inflammatory Agents; Anticonvulsants; Dexamethasone; Drug Eruptions; Edema; Enzyme Inhibitors; Eosinophilia; Face; Female; Fever; Humans; Liver; Male; Middle Aged; Nevirapine; Phenytoin; Prednisolone; Pruritus; Recurrence; Retrospective Studies; Thailand; Time Factors; Withholding Treatment; Young Adult | 2012 |
Clinical profiles of Stevens-Johnson syndrome among Thai patients.
Topics: Adolescent; Adult; Age Factors; Aged; Allopurinol; Female; Hepatitis; Humans; Male; Middle Aged; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; Sulfonamides; Thailand; Young Adult | 2014 |
Urate synthesis and oxidative stress in phenytoin hepatotoxicity: the role of antioxidant vitamins.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Folic Acid; Liver; Oxidative Stress; Phenytoin; Rats, Wistar; Superoxides; Uric Acid; Vitamin E; Xanthine Oxidase | 2014 |
Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study.
Topics: Adult; Aged; Allopurinol; Anticonvulsants; Carbamazepine; Case-Control Studies; Drug Combinations; Epilepsy; Female; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Phenytoin; Stevens-Johnson Syndrome; Taiwan | 2018 |
Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results.
Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Cicatrix; Humans; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; Taiwan | 2022 |
Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization.
Topics: Allopurinol; Carbamazepine; Humans; Pharmacovigilance; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; World Health Organization | 2022 |
Severe cutaneous adverse reactions: A 5-year retrospective study at Hospital Melaka, Malaysia, from December 2014 to February 2020.
Topics: Acute Generalized Exanthematous Pustulosis; Adult; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Cicatrix; Dermatitis, Exfoliative; Eosinophilia; Female; Hospitals; Humans; Malaysia; Male; Middle Aged; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome | 2022 |